Pathways

PathWhiz ID Pathway Meta Data

PW132100

Pw132100 View Pathway
physiological

Nicotinic Acetylcholine

Homo sapiens
Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral nervous system, muscle, and many other tissues of ma (more)

PW132105

Pw132105 View Pathway
physiological

Nicotinic Acetylcholine

Mus musculus
Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral nervous system, muscle, and many other tissues of ma (more)

PW132106

Pw132106 View Pathway
physiological

Nicotinic Acetylcholine

Rattus norvegicus
Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral nervous system, muscle, and many other tissues of ma (more)

PW132107

Pw132107 View Pathway
physiological

Nicotinic Acetylcholine

Bos taurus
Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral nervous system, muscle, and many other tissues of ma (more)

PW146998

Pw146998 View Pathway
metabolic

Nicotinic acid Drug Metabolism Pathway

Homo sapiens

PW124419

Pw124419 View Pathway
drug action

Nifedipine

Homo sapiens
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Since nifedipine's development, second and third genera (more)

PW000394

Pw000394 View Pathway
drug action

Nifedipine Action Pathway

Homo sapiens
Nifedipine (also known as Adalat or Procardia) is a dihydropyridine calcium channel blocker that may be used for treatment of hypertension and exertion-related angina in the absence of vasospasm. Nifedipine binds the major channel in muscle cells: L-type calcium channels. Binding of Nifedipin (more)

PW127889

Pw127889 View Pathway
drug action

Nifedipine Action Pathway (New)

Homo sapiens
Nifedipine is a dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. It can be found under the brand names Adalat, Afeditab CR, Nifediac, Nifedical, and Procardia. Nifedipine, or BAY a 1040, is a first generation dihydr (more)

PW145204

Pw145204 View Pathway
drug action

Nifedipine Drug Metabolism Action Pathway

Homo sapiens

PW124482

Pw124482 View Pathway
metabolic

Nifedipine Metabolic pathway

Homo sapiens
Nifedipine is predominantly metabolized by CYP3A4. Nifedipine is predominantly metabolized to 2,6-dimethyl-4-(2-nitrophenyl)-5-methoxycarbonyl-pyridine-3-carboxylic acid, and then further metabolized to 2-hydroxymethyl-pyridine carboxylic acid. Nifedipine is also minorly metabolized to dehydr (more)