
PathWhiz ID | Pathway | Meta Data |
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PW146195 |
drug action
Tetracycline phosphate complex Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:38 Last Updated: October 07, 2023 at 17:38 |
PW176235 |
Tetracycline Predicted Metabolism PathwayHomo sapiens
Metabolites of Tetracycline are predicted with biotransformer.
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Creator: Omolola Created On: December 04, 2023 at 13:03 Last Updated: December 04, 2023 at 13:03 |
PW146352 |
drug action
Tetradecyl hydrogen sulfate (ester) Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 18:00 Last Updated: October 07, 2023 at 18:00 |
PW176538 |
Tetradecyl hydrogen sulfate (ester) Predicted Metabolism PathwayHomo sapiens
Metabolites of Tetradecyl hydrogen sulfate (ester) are predicted with biotransformer.
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Creator: Omolola Created On: December 13, 2023 at 14:50 Last Updated: December 13, 2023 at 14:50 |
PW146835 |
drug action
Tetraferric tricitrate decahydrate Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 19:09 Last Updated: October 07, 2023 at 19:09 |
PW146991 |
Tetrahydrocannabinol Drug Metabolism PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 10, 2023 at 13:36 Last Updated: October 10, 2023 at 13:36 |
PW002417 |
Tetrahydrofolate BiosynthesisSaccharomyces cerevisiae
The biosynthesis of tetrahydrofolate begins with guanosine triphosphate interacting with water through GTP-cyclohydrlase resulting in the release of a formic acid, a hydrogen ion and a dihydroneopterin triphosphate. The latter compound then reacts with water in a spontaneous reaction resulting in the release of pyrophosphate, hydrogen ion and dihydroneopterinphosphate. Dihydroneopterin phosphate then reacts spontaneously with water resulting in the release of phosphate and 7,8-dihydroneopterin. This compound reacts wuth a folic acid synthesis enzyme resulting in the release of glycoaldehyde and 6-hydroxymethyl-7,8-dihydropterin. The latter compound is then diphosphorylated through an ATP driven folic acid synthesis resulting in the release of AMP, a hydrogen ion and 6-hydroxymethyl-7,8-dihydropterin diphosphate. This compound reacts with p-Aminobenzoic acid that is release from chorismate, the reaction happens through a folic acid synthesis resulting in the pyrophosphate and 7,8-dihydropteric acid. The latter compound reacts with glutamic acid through an ATP driven folic acid synthesis 3 resulting in the release of hydrogen ion, a phosphate, ADP and a 7,8-dihydrofolate monoglutamate. The latter compound reacts with a hydrogen ion through a NADPH through a dihydrofolate reductase resulting in the release of NADP and tetrahydrofolate. This compound can also be a result of 5,10 methenyltetrahydrofolic acid reacting with water through a mitochondrials c1-tetrahydrofolate synthase which releases a 10-formyltetrahydrofolate. This compound in turn reacts with a 5-phosphoribosyl-N-formylglycinamide through a glycinamide ribotide transformylase resulting in the release of a tetrahydrofolate and a 5'phosphoribosyl-N-fromylglycinamide.
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Creator: miguel ramirez Created On: January 15, 2016 at 15:26 Last Updated: January 15, 2016 at 15:26 |
PW123538 |
Tetrahydromonapterin BiosynthesisPseudomonas aeruginosa
This pathway demonstrates the biosynthesis of tetrahydromonapterin in E.coli. However, it is still unclear about biological role of tetrahydromonapterin. GTP cyclohydrolase 1 generates formic acid and 7,8-dihydroneopterin 3'-triphosphate with cofactor GTP and water. 7,8-dihydroneopterin 3'-triphosphate is converted to dihydromonapterin-triphosphate by d-erythro-7,8-dihydroneopterin triphosphate epimerase (folX). Later, dihydromonapterin-triphosphate is hydroxylated to dihydromethysticin, and eventually form tetrahydromonapterin via dihydromonapterin reductase (folM) with cofactor NADPH.
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Creator: Ana Marcu Created On: August 12, 2019 at 22:28 Last Updated: August 12, 2019 at 22:28 |
PW002043 |
Tetrahydromonapterin BiosynthesisEscherichia coli
This pathway demonstrates the biosynthesis of tetrahydromonapterin in E.coli. However, it is still unclear about biological role of tetrahydromonapterin. GTP cyclohydrolase 1 generates formic acid and 7,8-dihydroneopterin 3'-triphosphate with cofactor GTP and water. 7,8-dihydroneopterin 3'-triphosphate is converted to dihydromonapterin-triphosphate by d-erythro-7,8-dihydroneopterin triphosphate epimerase (folX). Later, dihydromonapterin-triphosphate is hydroxylated to dihydromethysticin, and eventually form tetrahydromonapterin via dihydromonapterin reductase (folM) with cofactor NADPH.
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Creator: Ana Marcu Created On: October 07, 2015 at 15:48 Last Updated: October 07, 2015 at 15:48 |
PW132271 |
Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate Drug MetabolismHomo sapiens
Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate passes through the liver and is then excreted from the body mainly through the kidney.
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Creator: Ray Kruger Created On: September 21, 2023 at 20:31 Last Updated: September 21, 2023 at 20:31 |