PathWhiz

PathWhiz ID	Pathway	Meta Data
PW122384 View Pathway	disease Cardiac Hypertophy Rattus norvegicus BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Selçuk Korkmaz Created On: March 13, 2019 at 13:32 Last Updated: March 13, 2019 at 13:32
PW126148 View Pathway	physiological Cardiac Cycle (Wiggers Diagram) Homo sapiens The Wiggers diagram is a tool used to teach cardiovascular physiology which typically includes pressure and volume changes during ventricular contractions (cardiac cycle). At the end of diastole (relaxation phase), the mitral valve closes and the left atrium contracts. When the left ventricular pressure exceeds aortic pressure, the aortic valve opens (systole), hits a peak and decreases as the volume in the left ventricle decreases. The aortic valve closes and slightly increases the pressure in the aorta (incisura). When the left ventricular pressure is below the left atrial pressure, the mitral valve opens and the left ventricle can begin filling with blood in order to repeat the process. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ashley Zubkowski Created On: June 30, 2021 at 17:35 Last Updated: June 30, 2021 at 17:35
PW122383 View Pathway	disease cardiac Mus musculus BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Selçuk Korkmaz Created On: March 13, 2019 at 13:29 Last Updated: March 13, 2019 at 13:29
PW146206 View Pathway	drug action Carboxymethylcellulose Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:40 Last Updated: October 07, 2023 at 17:40
PW175990 View Pathway	metabolic Carboxin Predicted Metabolism Pathway new Homo sapiens Metabolites of Carboxin are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: November 29, 2023 at 13:03 Last Updated: November 29, 2023 at 13:03
PW145567 View Pathway	drug action Carboxin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:05 Last Updated: October 07, 2023 at 16:05
PW144554 View Pathway	drug action Carboprost tromethamine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:53 Last Updated: October 07, 2023 at 13:53
PW132324 View Pathway	metabolic Carboprost tromethamine Drug Metabolism Homo sapiens Carboprost tromethamine is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Carboprost tromethamine passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 20:54 Last Updated: September 21, 2023 at 20:54
PW128625 View Pathway	drug action Carboprost tromethamine Action Pathway Homo sapiens Carboprost tromethamine is a medication primarily used in obstetrics and gynecology for two distinct purposes. First, it is employed as an abortifacient agent in the second trimester of pregnancy, typically between the 13th and 20th weeks of gestation. This is indicated when other methods of abortion have not been successful or in specific conditions such as premature rupture of membranes or the need for a repeat instillation of the drug for fetal expulsion. Second, it is used for the treatment of postpartum uterine hemorrhage due to atony when conventional methods of management have not proven effective. In both scenarios, carboprost tromethamine stimulates myometrial contractions within the uterus, similar to labor contractions, which help evacuate the products of conception in the case of abortion and provide hemostasis in postpartum hemorrhage. However, it can also lead to side effects such as vomiting, diarrhea, transient temperature increases, and, in some cases, bronchoconstriction. It's important to note that the use of carboprost tromethamine for abortion is a medical procedure carried out under specific circumstances and should only be administered by trained healthcare professionals in a clinical setting. Additionally, its use should be closely monitored to ensure both the effectiveness of the treatment and the well-being of the patient. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Dorsa Yahya Rayat Created On: September 06, 2023 at 20:41 Last Updated: September 06, 2023 at 20:41
PW145056 View Pathway	drug action Carboplatin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:00 Last Updated: October 07, 2023 at 15:00