
PathWhiz ID | Pathway | Meta Data |
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PW088387 |
Alanine MetabolismDrosophila melanogaster
Alanine (L-Alanine) is an α-amino acid that is used for protein biosynthesis. Approximately 8% of human proteins have alanine in their structures. The reductive lamination of pyruvate is effected by alanine transaminase. L-Alanine can be converted to pyruvic acid by alanine aminotransferase 1 reversibly coupled with interconversion of oxoglutaric acid and L-glutamic acid. L-Alanine can also be produced by alanine-glyoxylate transaminase with coupled interconversion of glyoxylate and glycine. L-Alanine will be coupled with alanyl tRNA by alanyl-tRNA synthetase to perform protein biosynthesis. Alanine can also be used to provide energy under fasting conditions. There are two pathways that can facilitate this: (1) alanine is converted to pyruvate to synthesize glucose via the gluconeogenesis pathway in liver tissue or (2) alanine converted into pyruvate moves into the TCA cycle to be oxidized in other tissues.
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Creator: Ana Marcu Created On: August 10, 2018 at 15:29 Last Updated: August 10, 2018 at 15:29 |
PW124221 |
protein
alanine metabolicactinobacillus succinogenes 130Z
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Creator: Miguel Angel Gamboa Created On: October 13, 2020 at 19:51 Last Updated: October 13, 2020 at 19:51 |
PW064420 |
signaling
Alanine 1510084330Homo sapiens
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Creator: Guest: Anonymous Created On: November 07, 2017 at 12:52 Last Updated: November 07, 2017 at 12:52 |
PW002500 |
drug action
alanine 1457415993Homo sapiens
|
Creator: Guest: Anonymous Created On: March 07, 2016 at 22:26 Last Updated: March 07, 2016 at 22:26 |
PW002020 |
drug action
alanine 1443043053Homo sapiens
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Creator: Guest: Anonymous Created On: September 23, 2015 at 15:17 Last Updated: September 23, 2015 at 15:17 |
PW002019 |
drug action
alanine 1443027279Homo sapiens
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Creator: Guest: Anonymous Created On: September 23, 2015 at 10:54 Last Updated: September 23, 2015 at 10:54 |
PW001865 |
signaling
Alanine 1441179314Homo sapiens
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Creator: Guest: Anonymous Created On: September 02, 2015 at 01:37 Last Updated: September 02, 2015 at 01:37 |
PW000979 |
drug action
alanine 1436993724Homo sapiens
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Creator: Guest: Anonymous Created On: July 15, 2015 at 14:55 Last Updated: July 15, 2015 at 14:55 |
PW123590 |
signaling
alanineHomo sapiens
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Creator: Guest: Anonymous Created On: September 09, 2019 at 01:54 Last Updated: September 09, 2019 at 01:54 |
PW000961 |
drug action
alanineHomo sapiens
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Creator: Guest: Anonymous Created On: July 01, 2015 at 02:46 Last Updated: July 01, 2015 at 02:46 |