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PathWhiz ID Pathway Meta Data

PW088387

Pw088387 View Pathway
metabolic

Alanine Metabolism

Drosophila melanogaster
Alanine (L-Alanine) is an α-amino acid that is used for protein biosynthesis. Approximately 8% of human proteins have alanine in their structures. The reductive lamination of pyruvate is effected by alanine transaminase. L-Alanine can be converted to pyruvic acid by alanine aminotransferase 1 reversibly coupled with interconversion of oxoglutaric acid and L-glutamic acid. L-Alanine can also be produced by alanine-glyoxylate transaminase with coupled interconversion of glyoxylate and glycine. L-Alanine will be coupled with alanyl tRNA by alanyl-tRNA synthetase to perform protein biosynthesis. Alanine can also be used to provide energy under fasting conditions. There are two pathways that can facilitate this: (1) alanine is converted to pyruvate to synthesize glucose via the gluconeogenesis pathway in liver tissue or (2) alanine converted into pyruvate moves into the TCA cycle to be oxidized in other tissues.

PW124221

Pw124221 View Pathway
protein

alanine metabolic

actinobacillus succinogenes 130Z

PW064420

Pw064420 View Pathway
signaling

Alanine 1510084330

Homo sapiens

PW002500

Pw002500 View Pathway
drug action

alanine 1457415993

Homo sapiens

PW002020

Pw002020 View Pathway
drug action

alanine 1443043053

Homo sapiens

PW002019

Pw002019 View Pathway
drug action

alanine 1443027279

Homo sapiens

PW001865

Pw001865 View Pathway
signaling

Alanine 1441179314

Homo sapiens

PW000979

Pw000979 View Pathway
drug action

alanine 1436993724

Homo sapiens

PW123590

Pw123590 View Pathway
signaling

alanine

Homo sapiens

PW000961

Pw000961 View Pathway
drug action

alanine

Homo sapiens