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PW401839

Pw401839 View Pathway
metabolic

Tyrosine Biosynthesis

Veillonella atypica ACS-049-V-Sch6
Tyrosine is one of the amino acid used in protein synthesis. The tyrosine biosynthesis pathways is connected with the chorismate biosynthesis pathway. Chorismate biosynthesis produce the chorismate, which can further be converted to prephenate by T-protein. Combined with cofactor, NAD, prephenate has been further converted to 4-Hydroxyphenylpyruvic acid by T-protein with generated NADH and carbon dioxide. Tyrosine aminotransferase catalyzes 4-Hydroxyphenylpyruvic acid to tyrosine, and also converts glutamic acid to oxoglutaric acid. Tyrosine will be further catalyzed into various molecules such as 2-iminoacetate, p-Cresol, 5'Deoxyadenosine and L-Methionine; or it will be exported from cell via the lysine exporter.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 19, 2024 at 07:38

Last Updated: December 19, 2024 at 07:38

PW401593

Pw401593 View Pathway
metabolic

Tyrosine Biosynthesis

Providencia stuartii ATCC 25827
Tyrosine is one of the amino acid used in protein synthesis. The tyrosine biosynthesis pathways is connected with the chorismate biosynthesis pathway. Chorismate biosynthesis produce the chorismate, which can further be converted to prephenate by T-protein. Combined with cofactor, NAD, prephenate has been further converted to 4-Hydroxyphenylpyruvic acid by T-protein with generated NADH and carbon dioxide. Tyrosine aminotransferase catalyzes 4-Hydroxyphenylpyruvic acid to tyrosine, and also converts glutamic acid to oxoglutaric acid. Tyrosine will be further catalyzed into various molecules such as 2-iminoacetate, p-Cresol, 5'Deoxyadenosine and L-Methionine; or it will be exported from cell via the lysine exporter.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 19, 2024 at 05:02

Last Updated: December 19, 2024 at 05:02

PW000806

Pw000806 View Pathway
metabolic

Tyrosine Biosynthesis

Escherichia coli
Tyrosine is one of the amino acid used in protein synthesis. The tyrosine biosynthesis pathways is connected with the chorismate biosynthesis pathway. Chorismate biosynthesis produce the chorismate, which can further be converted to prephenate by T-protein. Combined with cofactor, NAD, prephenate has been further converted to 4-Hydroxyphenylpyruvic acid by T-protein with generated NADH and carbon dioxide. Tyrosine aminotransferase catalyzes 4-Hydroxyphenylpyruvic acid to tyrosine, and also converts glutamic acid to oxoglutaric acid. Tyrosine will be further catalyzed into various molecules such as 2-iminoacetate, p-Cresol, 5'Deoxyadenosine and L-Methionine; or it will be exported from cell via the lysine exporter.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: miguel ramirez

Created On: March 15, 2015 at 16:37

Last Updated: March 15, 2015 at 16:37

PW409307

Pw409307 View Pathway
metabolic

Tyrosine Biosynthesis

Escherichia coli IHE3034
Tyrosine is one of the amino acid used in protein synthesis. The tyrosine biosynthesis pathways is connected with the chorismate biosynthesis pathway. Chorismate biosynthesis produce the chorismate, which can further be converted to prephenate by T-protein. Combined with cofactor, NAD, prephenate has been further converted to 4-Hydroxyphenylpyruvic acid by T-protein with generated NADH and carbon dioxide. Tyrosine aminotransferase catalyzes 4-Hydroxyphenylpyruvic acid to tyrosine, and also converts glutamic acid to oxoglutaric acid. Tyrosine will be further catalyzed into various molecules such as 2-iminoacetate, p-Cresol, 5'Deoxyadenosine and L-Methionine; or it will be exported from cell via the lysine exporter.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 23, 2024 at 11:36

Last Updated: December 23, 2024 at 11:36

PW408809

Pw408809 View Pathway
metabolic

Tyrosine Biosynthesis

Escherichia coli IAI1
Tyrosine is one of the amino acid used in protein synthesis. The tyrosine biosynthesis pathways is connected with the chorismate biosynthesis pathway. Chorismate biosynthesis produce the chorismate, which can further be converted to prephenate by T-protein. Combined with cofactor, NAD, prephenate has been further converted to 4-Hydroxyphenylpyruvic acid by T-protein with generated NADH and carbon dioxide. Tyrosine aminotransferase catalyzes 4-Hydroxyphenylpyruvic acid to tyrosine, and also converts glutamic acid to oxoglutaric acid. Tyrosine will be further catalyzed into various molecules such as 2-iminoacetate, p-Cresol, 5'Deoxyadenosine and L-Methionine; or it will be exported from cell via the lysine exporter.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 23, 2024 at 07:48

Last Updated: December 23, 2024 at 07:48

PW408777

Pw408777 View Pathway
metabolic

Tyrosine Biosynthesis

Escherichia coli UMN026
Tyrosine is one of the amino acid used in protein synthesis. The tyrosine biosynthesis pathways is connected with the chorismate biosynthesis pathway. Chorismate biosynthesis produce the chorismate, which can further be converted to prephenate by T-protein. Combined with cofactor, NAD, prephenate has been further converted to 4-Hydroxyphenylpyruvic acid by T-protein with generated NADH and carbon dioxide. Tyrosine aminotransferase catalyzes 4-Hydroxyphenylpyruvic acid to tyrosine, and also converts glutamic acid to oxoglutaric acid. Tyrosine will be further catalyzed into various molecules such as 2-iminoacetate, p-Cresol, 5'Deoxyadenosine and L-Methionine; or it will be exported from cell via the lysine exporter.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 23, 2024 at 07:32

Last Updated: December 23, 2024 at 07:32

PW408847

Pw408847 View Pathway
metabolic

Tyrosine Biosynthesis

Escherichia coli O157:H7 str. TW14359
Tyrosine is one of the amino acid used in protein synthesis. The tyrosine biosynthesis pathways is connected with the chorismate biosynthesis pathway. Chorismate biosynthesis produce the chorismate, which can further be converted to prephenate by T-protein. Combined with cofactor, NAD, prephenate has been further converted to 4-Hydroxyphenylpyruvic acid by T-protein with generated NADH and carbon dioxide. Tyrosine aminotransferase catalyzes 4-Hydroxyphenylpyruvic acid to tyrosine, and also converts glutamic acid to oxoglutaric acid. Tyrosine will be further catalyzed into various molecules such as 2-iminoacetate, p-Cresol, 5'Deoxyadenosine and L-Methionine; or it will be exported from cell via the lysine exporter.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: December 23, 2024 at 08:06

Last Updated: December 23, 2024 at 08:06

PW144277

Pw144277 View Pathway
drug action

Tyrosine Drug Metabolism Action Pathway

Homo sapiens
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Ray Kruger

Created On: October 07, 2023 at 13:05

Last Updated: October 07, 2023 at 13:05

PW000473

Pw000473 View Pathway
disease

Tyrosine Hydroxylase Deficiency

Homo sapiens
Tyrosine Hydroxylase (TH) Deficiency is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of catecholamines pathways. The disorder is caused by defects in the Tyrosine hydroxylase (TH) gene which encodes for the enzyme tyrosine hydroxylase. This enzyme is part of the production of catecholamines such as dopamine, norepinephrine and epinephrine are all essential for normal nervous system function. Dopamine transmits signals to help the brain control physical movement and emotional behavior. Norepinephrine and epinephrine are involved in the autonomic nervous system. Mutations in the TH gene result in reduced activity of the tyrosine hydroxylase enzyme. As a result, the body produces less dopamine, norepinephrine and epinephrine. Symptoms of the disorder include abnormal movements, autonomic dysfunction, and other neurological problems. Treatments can include the administration of levodopa; however patient responses can vary greatly. The frequency of Tyrosine Hydroxylase Deficiency is unknown.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: WishartLab

Created On: August 29, 2013 at 10:38

Last Updated: August 29, 2013 at 10:38

PW127175

Pw127175 View Pathway
disease

Tyrosine Hydroxylase Deficiency

Homo sapiens
Tyrosine Hydroxylase (TH) Deficiency is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of catecholamines pathways. The disorder is caused by defects in the Tyrosine hydroxylase (TH) gene which encodes for the enzyme tyrosine hydroxylase. This enzyme is part of the production of catecholamines such as dopamine, norepinephrine and epinephrine are all essential for normal nervous system function. Dopamine transmits signals to help the brain control physical movement and emotional behavior. Norepinephrine and epinephrine are involved in the autonomic nervous system. Mutations in the TH gene result in reduced activity of the tyrosine hydroxylase enzyme. As a result, the body produces less dopamine, norepinephrine and epinephrine. Symptoms of the disorder include abnormal movements, autonomic dysfunction, and other neurological problems. Treatments can include the administration of levodopa; however patient responses can vary greatly. The frequency of Tyrosine Hydroxylase Deficiency is unknown.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Ray Kruger

Created On: November 02, 2022 at 10:26

Last Updated: November 02, 2022 at 10:26