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PathWhiz ID Pathway Meta Data

PW122551

Pw122551 View Pathway
signaling

1.      Barrier 1564688413

Homo sapiens
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Guest: Anonymous

Created On: August 01, 2019 at 13:40

Last Updated: August 01, 2019 at 13:40

PW122539

Pw122539 View Pathway
signaling

1.      Barrier 1562761104

Homo sapiens
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Guest: Anonymous

Created On: July 10, 2019 at 06:18

Last Updated: July 10, 2019 at 06:18

PW064700

Pw064700 View Pathway
signaling

1.      Barrier

Homo sapiens
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Guest: Anonymous

Created On: March 16, 2018 at 21:18

Last Updated: March 16, 2018 at 21:18

PW146354

Pw146354 View Pathway
drug action

1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) Drug Metabolism Action Pathway

Homo sapiens
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Ray Kruger

Created On: October 07, 2023 at 18:00

Last Updated: October 07, 2023 at 18:00

PW126354

Pw126354 View Pathway
metabolic

1-Methylhistidine synthesis via METTL9-catalyzed methylation

Homo sapiens
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Selena

Created On: October 13, 2021 at 21:24

Last Updated: October 13, 2021 at 21:24

PW126201

Pw126201 View Pathway
metabolic

1-Methylhistidine Metabolism

Homo sapiens
Methylhistidine is a modified amino acid that is produced in myocytes during the methylation of actin and myosin. It is also formed from the methylation of L-histidine, which takes the methyl group from S-adenosylmethionine and forms S-adenosylhomocysteine as a byproduct. After its formation in the myocytes, methylhistidine enters the blood stream and travels to the kidneys, where it is excreted in the urine. Methylhistidine is present in the blood and urine in higher concentrations after skeletal muscle protein breakdown, which can occur due to disease or injury. Because of this, it can be used to judge how much muscle breakdown is occurring. Methylhistidine levels are also affected by diet, and may differ between vegetarian diets and those containing meats.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Selena

Created On: August 23, 2021 at 15:10

Last Updated: August 23, 2021 at 15:10

PW495634

Pw495634 View Pathway
metabolic

1,6-Anhydro-N-acetylmuramic Acid Recycling

Escherichia coli (strain K12)
Most bacteria, including Escherichia coli, are composed of murein which protects and stabilizes the cell wall. Over half of the murein is broken down by Escherichia coli and recycled for the next generation. The main muropeptide is GlcNAc-anhydro-N-acetylmuramic acid (anhMurNAc)-l-Ala-γ-d-Glu-meso-Dap-d-Ala which enters the cytoplasm by AmpG protein. The peptide is then released from the muropeptide. 1,6-Anhydro-N-acetylmuramic acid (anhMurNAc) is recycled by its conversion to N-acetylglucosamine-phosphate (GlcNAc-P). The sugar is phosphorylated by anhydro-N-acetylmuramic acid kinase (AnmK) to produce MurNAc-P. Etherase cleaves MurNAc-P to produce N-acetyl-D-glucosamine 6-phosphate. The product can undergo further degradation or be recycled into peptidoglycan monomers. The pathway's final product is a peptidoglycan biosynthesis precursor, UDP-N-acetyl-α-D-muramate. The enzyme muropeptide ligase (mpl), attaches the recovered Ala-Glu-DAP tripeptide to the precursor UDP-N-acetyl-α-D-muramate to return to the peptide to the peptidoglycan biosynthetic pathway to synthesize the cell wall.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 03, 2025 at 12:56

Last Updated: February 03, 2025 at 12:56

PW495684

Pw495684 View Pathway
metabolic

1,6-Anhydro-N-acetylmuramic Acid Recycling

Escherichia coli (strain 55989 / EAEC)
Most bacteria, including Escherichia coli, are composed of murein which protects and stabilizes the cell wall. Over half of the murein is broken down by Escherichia coli and recycled for the next generation. The main muropeptide is GlcNAc-anhydro-N-acetylmuramic acid (anhMurNAc)-l-Ala-γ-d-Glu-meso-Dap-d-Ala which enters the cytoplasm by AmpG protein. The peptide is then released from the muropeptide. 1,6-Anhydro-N-acetylmuramic acid (anhMurNAc) is recycled by its conversion to N-acetylglucosamine-phosphate (GlcNAc-P). The sugar is phosphorylated by anhydro-N-acetylmuramic acid kinase (AnmK) to produce MurNAc-P. Etherase cleaves MurNAc-P to produce N-acetyl-D-glucosamine 6-phosphate. The product can undergo further degradation or be recycled into peptidoglycan monomers. The pathway's final product is a peptidoglycan biosynthesis precursor, UDP-N-acetyl-α-D-muramate. The enzyme muropeptide ligase (mpl), attaches the recovered Ala-Glu-DAP tripeptide to the precursor UDP-N-acetyl-α-D-muramate to return to the peptide to the peptidoglycan biosynthetic pathway to synthesize the cell wall.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 03, 2025 at 13:32

Last Updated: February 03, 2025 at 13:32

PW499112

Pw499112 View Pathway
metabolic

1,6-Anhydro-N-acetylmuramic Acid Recycling

Bacteroides uniformis ATCC 8492
Most bacteria, including Escherichia coli, are composed of murein which protects and stabilizes the cell wall. Over half of the murein is broken down by Escherichia coli and recycled for the next generation. The main muropeptide is GlcNAc-anhydro-N-acetylmuramic acid (anhMurNAc)-l-Ala-γ-d-Glu-meso-Dap-d-Ala which enters the cytoplasm by AmpG protein. The peptide is then released from the muropeptide. 1,6-Anhydro-N-acetylmuramic acid (anhMurNAc) is recycled by its conversion to N-acetylglucosamine-phosphate (GlcNAc-P). The sugar is phosphorylated by anhydro-N-acetylmuramic acid kinase (AnmK) to produce MurNAc-P. Etherase cleaves MurNAc-P to produce N-acetyl-D-glucosamine 6-phosphate. The product can undergo further degradation or be recycled into peptidoglycan monomers. The pathway's final product is a peptidoglycan biosynthesis precursor, UDP-N-acetyl-α-D-muramate. The enzyme muropeptide ligase (mpl), attaches the recovered Ala-Glu-DAP tripeptide to the precursor UDP-N-acetyl-α-D-muramate to return to the peptide to the peptidoglycan biosynthetic pathway to synthesize the cell wall.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 04, 2025 at 17:27

Last Updated: February 04, 2025 at 17:27

PW501354

Pw501354 View Pathway
metabolic

1,6-Anhydro-N-acetylmuramic Acid Recycling

Morganella morganii subsp. morganii KT
Most bacteria, including Escherichia coli, are composed of murein which protects and stabilizes the cell wall. Over half of the murein is broken down by Escherichia coli and recycled for the next generation. The main muropeptide is GlcNAc-anhydro-N-acetylmuramic acid (anhMurNAc)-l-Ala-γ-d-Glu-meso-Dap-d-Ala which enters the cytoplasm by AmpG protein. The peptide is then released from the muropeptide. 1,6-Anhydro-N-acetylmuramic acid (anhMurNAc) is recycled by its conversion to N-acetylglucosamine-phosphate (GlcNAc-P). The sugar is phosphorylated by anhydro-N-acetylmuramic acid kinase (AnmK) to produce MurNAc-P. Etherase cleaves MurNAc-P to produce N-acetyl-D-glucosamine 6-phosphate. The product can undergo further degradation or be recycled into peptidoglycan monomers. The pathway's final product is a peptidoglycan biosynthesis precursor, UDP-N-acetyl-α-D-muramate. The enzyme muropeptide ligase (mpl), attaches the recovered Ala-Glu-DAP tripeptide to the precursor UDP-N-acetyl-α-D-muramate to return to the peptide to the peptidoglycan biosynthetic pathway to synthesize the cell wall.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 05, 2025 at 13:14

Last Updated: February 05, 2025 at 13:14