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PW002488

Pw002488 View Pathway
metabolic

Vitamin B6

Saccharomyces cerevisiae
Vitamin B6 belongs to the vitamin B complex group and is water-soluble. The active form is Pyridoxal phosphate (PLP) which acts as a cofactor for various essential enzymes in reactions including: amino acid metabolism, transamination, deamination, and decarboxylation. Other forms of the vitamin include: pyridoxine (PN), pyridoxine 5’-phosphate (PNP), pyridoxal (PL), pyridoxamine (PM), pyridoxamine 5’-phosphate (PMP), and 4-pyridoxic acid (PA). Most animals are unable to synthesize the vitamin while most bacteria are able too. Some organisms also import the vitamin to supplement or augment biosynthesis. S. cerevisiae has transporter Tpn1p on the plasma membrane to import vitamin B6. It transports mostly PN, a precursor of PLP, but also PM and PL. Vitamin B6 is also an antioxidant to provide protection against reactive oxygen species. It has been shown that vitamin B6 synthesis is increased in response to cell stress.
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Creator: miguel ramirez

Created On: February 29, 2016 at 11:09

Last Updated: February 29, 2016 at 11:09

PW533838

Pw533838 View Pathway
metabolic

Vitamin B6 Metabolism

Xanthomonas campestris
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 20, 2025 at 03:26

Last Updated: February 20, 2025 at 03:26

PW536154

Pw536154 View Pathway
metabolic

Vitamin B6 Metabolism

Raoultella planticola ATCC 33531
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 21, 2025 at 00:30

Last Updated: February 21, 2025 at 00:30

PW534949

Pw534949 View Pathway
metabolic

Vitamin B6 Metabolism

Pseudomonas stutzeri A1501
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 20, 2025 at 10:59

Last Updated: February 20, 2025 at 10:59

PW536130

Pw536130 View Pathway
metabolic

Vitamin B6 Metabolism

Escherichia sp. 1_1_43
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 21, 2025 at 00:09

Last Updated: February 21, 2025 at 00:09

PW536471

Pw536471 View Pathway
metabolic

Vitamin B6 Metabolism

Vibrio fluvialis I21563
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 21, 2025 at 03:48

Last Updated: February 21, 2025 at 03:48

PW533302

Pw533302 View Pathway
metabolic

Vitamin B6 Metabolism

Escherichia coli O157:H7
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 19, 2025 at 23:32

Last Updated: February 19, 2025 at 23:32

PW686645

Pw686645 View Pathway
metabolic

Vitamin B6 Metabolism

Escherichia albertii KF1
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 20, 2025 at 23:44

Last Updated: February 20, 2025 at 23:44

PW000891

Pw000891 View Pathway
metabolic

Vitamin B6 Metabolism

Escherichia coli
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Ana Marcu

Created On: May 06, 2015 at 12:16

Last Updated: May 06, 2015 at 12:16

PW535516

Pw535516 View Pathway
metabolic

Vitamin B6 Metabolism

Parabacteroides johnsonii DSM 18315
Vitamin B6 metabolism in bacteria involves the biosynthesis and utilization of various forms of Vitamin B6, primarily pyridoxal 5'-phosphate (PLP), the active form of the vitamin. Bacteria can synthesize Vitamin B6 through two main pathways: the de novo DXP-independent pathway (pyridoxal phosphate biosynthesis I) and the DXP-dependent pathway. In the de novo pathway, key enzymes like Pdx1 and Pdx2 convert intermediates into pyridoxine 5'-phosphate (PNP), which is then oxidized to PLP by the enzyme pyridoxine phosphate oxidase (PdxH). PLP acts as a cofactor for various enzymes involved in amino acid metabolism, including transaminases, decarboxylases, and racemases.Bacteria rely on PLP for critical cellular processes, including amino acid metabolism, stress response, and protection against oxidative damage.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: February 20, 2025 at 17:00

Last Updated: February 20, 2025 at 17:00