SMP0126185
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Betaxolol B1-Adrenergic Cardiac Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: passes through hepatic portal circulation, and enters the bloodstream and travels to act on … cardiomyocytes. In bronchial and vascular smooth muscle, betaxolol can compete with epinephrine for beta … cAMP synthesis, which in turn activates PKA production, which then activates SRC and nitric oxide … synthase, its inhibition causes the inhibition of cAMP, PKA, SRC and nitric oxide synthase signaling … reaction chain, the inhibition of SRC in essence causes the activation of Caspase 3 and Caspase 9. This
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SMP0126221
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Practolol Action Pathway (New)
Homo sapiens
Matched Description: through hepatic portal circulation, and enters the bloodstream and travels to act on cardiomyocytes. In … bronchial and vascular smooth muscle, practolol can compete with epinephrine for beta-2 adrenergic … synthesis, which in turn activates PKA production, which then activates SRC and nitric oxide synthase, its … inhibition causes the inhibition of cAMP, PKA, SRC and nitric oxide synthase signaling. Following … , the inhibition of SRC in essence causes the activation of Caspase 3 and Caspase 9. This Caspase
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SMP0122688
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Hydrochlorothiazide Diuretic Action Pathway
Homo sapiens
Matched Description: , severe resistant edema, nephrogenic diabetes insipidus, and to prevent kidney stone formation in … , potassium, calcium, chloride, and magnesium occurs. In epithelial cells of the DCT, the … basolateral membrane consists of the Na+/K+ ATPase, which pumps Na+ into the interstitium-blood area and K … + into the epithelial cell; the Na+/Ca2+ exchanger, which pumps Na+ into the cell and Ca2+ into the … interstitium-blood; and the chloride transporter which transports chloride into the interstitium-blood
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SMP0174896
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Carbinoxamine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune response, in
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SMP0174901
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Mequitazine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and
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SMP0174908
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Methapyrilene H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune response, in
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SMP0174913
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Chloropyramine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: action of histamine at the H1 receptor and are administered to attenuate inflammatory process in … order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1 … constrict dilated blood vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1 … -antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered … conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the
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SMP0174916
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Ebastine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and
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SMP0174921
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Methdilazine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … vessels, and in smooth muscles of lungs and intestines to relax those muscles.
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune response, in
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SMP0174928
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Quetiapine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
Homo sapiens
Matched Description: at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … vessels, and in smooth muscles of lungs and intestines to relax those muscles
H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and
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