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Matched Description: abnormality in the dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene … abnormality makes it harder for dopamine and norepinephrine to bind to the receptors. These receptors … regulate attention, movement, and impulsivity, so a deficiency in the regulation of those systems … causes ADHD. Dexmethylphenidate blocks the reuptake transporters of dopamine and norepinephrine … into the synapse when the neuron is stimulated and fires. Dexmethylphenidate binds to the sodium

Matched Description: Metoclopramide is a dopamine receptor antagonist and has been approved by the FDA to treat nausea … and vomiting in patients with gastroesophageal reflux disease or diabetic gastroparesis by increasing … gastric motility.. Metoclopramide works by antagonizing central and peripheral dopamine-two … antagonist at 5HT3 (type 3 serotonin receptors) and an agonist at 5HT4 receptors. Metoclopramide's agonism of … enhancing gastric emptying and promoting peristalsis. This effect can be beneficial in conditions

Matched Description: Verapamil, known as the brand names Calan, Isoptin, Tarka, and Verelan, is a non-dihydropyridine … calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. It is used for … the prophylaxis of repetitive paroxysmal supraventricular tachycardia,and atrial fibrillation or … release with a short duration of action. Verapamil acts on smooth muscles and cardiac muscles … activation threshold and slow inactivation profile. L-type calcium channels are the main current

Matched Description: Lidocaine is a local anesthetic used in a wide variety of superficial and invasive procedures. It … , Xylocaine, Xylocaine With Epinephrine, Xylocard, Xylonor, Zingo, and Ztlido. Ever since its … discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally … , resulting in effects like vasodilation, hypotension, and irregular heart rate, among others. As a … nervous system and cardiovascular system. After absorption, lidocaine may cause stimulation of the

Matched Description: Bezafibrate is a lipid-lowering fibrate used in the management of primary and secondary … PPARα-RXRα complex regulate gene transcription/translation of proteins and enzymes involved … lipolysis, fatty acid transport and biosynthesis, vLDL and HDL synthesis. Fatty acid biosynthesis is … apolipoprotein A1 (APOA1) and apolipoproteins A2 (APOA2), which forms part of HDL. HDL is considered good … cholesterol. VLDL and LDL are considered bad cholesterol. These levels are decreased due to downregulation

Matched Description: Oxybutynin is an antimuscarinic agent used to relax the bladder and prevent the urge to void. It … can be taken either orally or intravenously. The bioavailability and the elimination half-life are … both increased in the elderly. When taken orally, oxybutynin enters the intestine and is transported … metabolized by cytochrome P450 3A4 in both the intesine wall and the liver. In the endoplasmic reticulum of … phenylcyclohexylglycolic acid also by cytochrome P450 3A4. Both metabolites and the remaining original

Matched Description: ,octacis-undecaprenol and a Uridine 5'-monophosphate. The N-acetyl-α-D-glucosaminyl-diphospho-ditrans … ,octacis-undecaprenol then reacts with an UDP-ManNAcA from the Amino sugar and nucleotide sugar … resulting in a uridine 5' diphosphate, a hydrogen ion and a Undecaprenyl N-acetyl-glucosaminyl-N-acetyl … metabolize by interacting with a hydrogen ion and a thymidine 5-triphosphate by either reacting with a … pyrophosphate and a dTDP-D-glucose. The latter compound is then dehydrated through an dTDP-glucose 4,6

Matched Description: ,octacis-undecaprenol and a Uridine 5'-monophosphate. The N-acetyl-α-D-glucosaminyl-diphospho-ditrans … ,octacis-undecaprenol then reacts with an UDP-ManNAcA from the Amino sugar and nucleotide sugar … resulting in a uridine 5' diphosphate, a hydrogen ion and a Undecaprenyl N-acetyl-glucosaminyl-N-acetyl … metabolize by interacting with a hydrogen ion and a thymidine 5-triphosphate by either reacting with a … pyrophosphate and a dTDP-D-glucose. The latter compound is then dehydrated through an dTDP-glucose 4,6

Matched Description: ,octacis-undecaprenol and a Uridine 5'-monophosphate. The N-acetyl-α-D-glucosaminyl-diphospho-ditrans … ,octacis-undecaprenol then reacts with an UDP-ManNAcA from the Amino sugar and nucleotide sugar … resulting in a uridine 5' diphosphate, a hydrogen ion and a Undecaprenyl N-acetyl-glucosaminyl-N-acetyl … metabolize by interacting with a hydrogen ion and a thymidine 5-triphosphate by either reacting with a … pyrophosphate and a dTDP-D-glucose. The latter compound is then dehydrated through an dTDP-glucose 4,6

Matched Description: ,octacis-undecaprenol and a Uridine 5'-monophosphate. The N-acetyl-α-D-glucosaminyl-diphospho-ditrans … ,octacis-undecaprenol then reacts with an UDP-ManNAcA from the Amino sugar and nucleotide sugar … resulting in a uridine 5' diphosphate, a hydrogen ion and a Undecaprenyl N-acetyl-glucosaminyl-N-acetyl … metabolize by interacting with a hydrogen ion and a thymidine 5-triphosphate by either reacting with a … pyrophosphate and a dTDP-D-glucose. The latter compound is then dehydrated through an dTDP-glucose 4,6