SMP0119384
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Hop Pathway in Cardiac Development
Bos taurus
Matched Description: of homeodomain factors tend to conglomerate and are responsible for anterior-posterior patterning … . There is much to be said as well regarding the development and growth of cardiac myocytes and … (namely: serum response factor (SRF), and GATA4) and a homeodomain factor known as Nkx2-5! The joint … development. The Hop gene is downstream of the Mkx2-5 factor we discussed earlier, and similar to it … exit the cycle at the correct stage and continue grow after normal developmental stage has finished
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SMP0119375
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Hop Pathway in Cardiac Development
Mus musculus
Matched Description: of homeodomain factors tend to conglomerate and are responsible for anterior-posterior patterning … . There is much to be said as well regarding the development and growth of cardiac myocytes and … (namely: serum response factor (SRF), and GATA4) and a homeodomain factor known as Nkx2-5! The joint … development. The Hop gene is downstream of the Mkx2-5 factor we discussed earlier, and similar to it … exit the cycle at the correct stage and continue grow after normal developmental stage has finished
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SMP0126994
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Dextroamphetamine Dopamine Reuptake Inhibitor Action Pathway
Homo sapiens
Matched Description: Dextroamphetamine, known commonly as Adderall, is a drug related to amphetamine and is used mainly … for treating ADHD and narcolepsy. The drug was approved by the FDA in 2001 for treating ADHD, but … dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene. It has also … makes it harder for dopamine and norepinephrine to bind to the receptors. These receptors regulate … attention, movement, and impulsivity, so a deficiency in regulating those systems causes ADHD
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SMP0127029
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Gq Serotonergic Smooth Muscle Contraction
Mus musculus
Matched Description: due to its prominent role in promoting airway smooth muscle contraction and contraction of the … gastrointestinal tract. Once activated, serotonin functions to mobilize intestinal contraction and … a conformational change that promotes its association with and activation of the heterotrimeric G … protein Gq. The extreme C-terminus of the G alpha subunit is the receptor recognition domain and … dictates receptor-Gα specificity. Receptor-Gα association promotes the release of GDP from Gα and binding
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SMP0126990
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Lisdexamfetamine Dopamine Reuptake Inhibitor Action Pathway
Homo sapiens
Matched Description: Lisdexamfetamine, known commonly as Vyvanse, is a prodrug of amphetamine paired with lysine and … used mainly for treating ADHD and binge eating disorders. The drug was engineered to be abuse-resistant … ), the D4 receptor gene (DRD-4), and/or the D2 receptor gene. It has also been found to affect the alpha … -2A adrenergic receptor in the prefrontal cortex. This abnormality makes it harder for dopamine and … norepinephrine to bind to the receptors. These receptors regulate attention, movement, and
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SMP0119400
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Hop Pathway in Cardiac Development
Rattus norvegicus
Matched Description: of homeodomain factors tend to conglomerate and are responsible for anterior-posterior patterning … . There is much to be said as well regarding the development and growth of cardiac myocytes and … (namely: serum response factor (SRF), and GATA4) and a homeodomain factor known as Nkx2-5! The joint … development. The Hop gene is downstream of the Mkx2-5 factor we discussed earlier, and similar to it … exit the cycle at the correct stage and continue grow after normal developmental stage has finished
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SMP0126676
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Levetiracetam Action Pathway (New)
Homo sapiens
Matched Description: , myoclonic, and generalized tonic-clonic seizures in patients with epilepsy.
The exact mechanism … that is found on synaptic vesicles and is ubiquitous throughout the CNS - it appears to play a role … in vesicle exocytosis and in the modulation of synaptic transmission by increasing the available … receptors such a AMPA and NMDA glutamate receptors are reduced. These receptors allow the influx of … cations like sodium and calcium ions into the post-synaptic cell when activated. Cation influx would
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SMP0090879
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Hop Pathway in Cardiac Development
Homo sapiens
Matched Description: of homeodomain factors tend to conglomerate and are responsible for anterior-posterior patterning … . There is much to be said as well regarding the development and growth of cardiac myocytes and … (namely: serum response factor (SRF), and GATA4) and a homeodomain factor known as Nkx2-5! The joint … development. The Hop gene is downstream of the Mkx2-5 factor we discussed earlier, and similar to it … exit the cycle at the correct stage and continue grow after normal developmental stage has finished
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SMP0000631
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Prednisone Metabolism Pathway
Homo sapiens
Matched Description: cytokine pathways type 1 and type 2. It is administered orally, through tablet, or solution … (concentrated or non-concentrated). Prednisone is a glucocorticoid, and as well as being used for immune system
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SMP0000675
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Diphenoxylate Action Pathway
Homo sapiens
Matched Description: diphenoxylate will eventually lead to reduced pain because of decreased nerve conduction and release of … neurotransmitter. Hyperpolarization of neuron is caused by inactivation of calcium channels and
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