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Matched Description: / acetolactate synthase resulting in the release of carbon dioxide and (S)-2-acetolactate. The latter … resulting in the release of a NADP and an (R) 2,3-dihydroxy-3-methylvalerate. The latter compound is … then dehydrated by a dihydroxy acid dehydratase resulting in the release of water and isovaleric … oxoglutaric acid and an L-valine. L-valine is then transported into the periplasmic space through a L-valine efflux transporter.

Matched Description: Pregabalin is an anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia … , and for the treatment of partial onset seizures in combination with other anticonvulsants. Pregabalin … properties include anxiolytic, anticonvulsant and analgesic effects. Although the structure of … amino acid glutamine and transported into synaptic vesicles by excitatory amino acid transporter and … neurotransmitter, thus, once it gets in the synapse it activates NMDA and AMPA receptors. Activation

Matched Description: administered via IV or oral inhalation and is used to treat conditions including mild or transient episodes … of heart block that do not require pacing, serious episodes of heart block and Adams-Stokes attacks … or pacemaker therapy is available, bronchospasm occurring during anesthesia, and as an adjunct to … in the treatment of hypovolemic and septic shock, low cardiac output states, congestive heart failure … , and cardiogenic shock. The actions of isoprenaline are mostly observed in heart muscle, where it

Matched Description: due to its prominent role in promoting airway smooth muscle contraction and contraction of the … gastrointestinal tract. Once activated, serotonin functions to mobilize intestinal contraction and … a conformational change that promotes its association with and activation of the heterotrimeric G … protein Gq. The extreme C-terminus of the G alpha subunit is the receptor recognition domain and … dictates receptor-Gα specificity. Receptor-Gα association promotes the release of GDP from Gα and binding

Matched Description: due to its prominent role in promoting airway smooth muscle contraction and contraction of the … gastrointestinal tract. Once activated, serotonin functions to mobilize intestinal contraction and … a conformational change that promotes its association with and activation of the heterotrimeric G … protein Gq. The extreme C-terminus of the G alpha subunit is the receptor recognition domain and … dictates receptor-Gα specificity. Receptor-Gα association promotes the release of GDP from Gα and binding

Matched Description: heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Also used in the … regulation of ions such as sodium, potassium, calcium, chloride and magnesium occur. In epithelial … interstitium-blood area and K+ into the epithelial cell; the Na+/Ca2+ exchanger, which pumps Na+ into … the cell and Ca2+ into the interstitium-blood; and the chloride transporter which transports chloride … epithelial cell and a Na+/Cl- cotransporter which transports Na+ and Cl- into the epithelial cell

Matched Description: due to its prominent role in promoting airway smooth muscle contraction and contraction of the … gastrointestinal tract. Once activated, serotonin functions to mobilize intestinal contraction and … a conformational change that promotes its association with and activation of the heterotrimeric G … protein Gq. The extreme C-terminus of the G alpha subunit is the receptor recognition domain and … dictates receptor-Gα specificity. Receptor-Gα association promotes the release of GDP from Gα and binding

Matched Description: of homeodomain factors tend to conglomerate and are responsible for anterior-posterior patterning … . There is much to be said as well regarding the development and growth of cardiac myocytes and … (namely: serum response factor (SRF), and GATA4) and a homeodomain factor known as Nkx2-5! The joint … development. The Hop gene is downstream of the Mkx2-5 factor we discussed earlier, and similar to it … exit the cycle at the correct stage and continue grow after normal developmental stage has finished

Matched Description: of homeodomain factors tend to conglomerate and are responsible for anterior-posterior patterning … . There is much to be said as well regarding the development and growth of cardiac myocytes and … (namely: serum response factor (SRF), and GATA4) and a homeodomain factor known as Nkx2-5! The joint … development. The Hop gene is downstream of the Mkx2-5 factor we discussed earlier, and similar to it … exit the cycle at the correct stage and continue grow after normal developmental stage has finished

Matched Description: Dextroamphetamine, known commonly as Adderall, is a drug related to amphetamine and is used mainly … for treating ADHD and narcolepsy. The drug was approved by the FDA in 2001 for treating ADHD, but … dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene. It has also … makes it harder for dopamine and norepinephrine to bind to the receptors. These receptors regulate … attention, movement, and impulsivity, so a deficiency in regulating those systems causes ADHD