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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 526139 results

SMP0127029

Pw128648 View Pathway
Metabolite

Gq Serotonergic Smooth Muscle Contraction

Mus musculus

  • Matched Description: due to its prominent role in promoting airway smooth muscle contraction and contraction of the … gastrointestinal tract. Once activated, serotonin functions to mobilize intestinal contraction and … a conformational change that promotes its association with and activation of the heterotrimeric G … protein Gq. The extreme C-terminus of the G alpha subunit is the receptor recognition domain and … dictates receptor-Gα specificity. Receptor-Gα association promotes the release of GDP from Gα and binding

  • Physiological

    SMP0126990

    Pw128608 View Pathway
    Metabolite

    Lisdexamfetamine Dopamine Reuptake Inhibitor Action Pathway

    Homo sapiens

  • Matched Description: Lisdexamfetamine, known commonly as Vyvanse, is a prodrug of amphetamine paired with lysine and … used mainly for treating ADHD and binge eating disorders. The drug was engineered to be abuse-resistant … ), the D4 receptor gene (DRD-4), and/or the D2 receptor gene. It has also been found to affect the alpha … -2A adrenergic receptor in the prefrontal cortex. This abnormality makes it harder for dopamine and … norepinephrine to bind to the receptors. These receptors regulate attention, movement, and

  • Drug Action

    SMP0119400

    Pw120623 View Pathway
    Metabolite

    Hop Pathway in Cardiac Development

    Rattus norvegicus

  • Matched Description: of homeodomain factors tend to conglomerate and are responsible for anterior-posterior patterning … . There is much to be said as well regarding the development and growth of cardiac myocytes and … (namely: serum response factor (SRF), and GATA4) and a homeodomain factor known as Nkx2-5! The joint … development. The Hop gene is downstream of the Mkx2-5 factor we discussed earlier, and similar to it … exit the cycle at the correct stage and continue grow after normal developmental stage has finished

  • Physiological

    SMP0126676

    Pw128280 View Pathway
    Metabolite

    Levetiracetam Action Pathway (New)

    Homo sapiens

  • Matched Description: , myoclonic, and generalized tonic-clonic seizures in patients with epilepsy. The exact mechanism … that is found on synaptic vesicles and is ubiquitous throughout the CNS - it appears to play a role … in vesicle exocytosis and in the modulation of synaptic transmission by increasing the available … receptors such a AMPA and NMDA glutamate receptors are reduced. These receptors allow the influx of … cations like sodium and calcium ions into the post-synaptic cell when activated. Cation influx would

  • Drug Action

    SMP0090879

    Pw091899 View Pathway
    Metabolite

    Hop Pathway in Cardiac Development

    Homo sapiens

  • Matched Description: of homeodomain factors tend to conglomerate and are responsible for anterior-posterior patterning … . There is much to be said as well regarding the development and growth of cardiac myocytes and … (namely: serum response factor (SRF), and GATA4) and a homeodomain factor known as Nkx2-5! The joint … development. The Hop gene is downstream of the Mkx2-5 factor we discussed earlier, and similar to it … exit the cycle at the correct stage and continue grow after normal developmental stage has finished

  • Physiological

    SMP0000631

    Pw000607 View Pathway
    Metabolite

    Prednisone Metabolism Pathway

    Homo sapiens

  • Matched Description: cytokine pathways type 1 and type 2. It is administered orally, through tablet, or solution … (concentrated or non-concentrated). Prednisone is a glucocorticoid, and as well as being used for immune system

  • Drug Metabolism

    SMP0000675

    Pw000652 View Pathway
    Metabolite

    Diphenoxylate Action Pathway

    Homo sapiens

  • Matched Description: diphenoxylate will eventually lead to reduced pain because of decreased nerve conduction and release of … neurotransmitter. Hyperpolarization of neuron is caused by inactivation of calcium channels and

  • Drug Action

    SMP0000406

    Pw000412 View Pathway
    Metabolite

    Morphine Action Pathway

    Homo sapiens

  • Matched Description: cyclase, reducing the level of intracellular cAMP. G(i) also activates potassium channels and … conduction and reduced neurotransmitter release, which blocks the perception of pain signals.

  • Drug Action

    SMP0000411

    Pw000417 View Pathway
    Metabolite

    Hydrocodone Action Pathway

    Homo sapiens

  • Matched Description: will eventually lead to reduced pain because of decreased nerve conduction and release of … neurotransmitter. Hyperpolarization of neuron is caused by inactivation of calcium channels and activation of potassium channels via facilitated by G-protein.

  • Drug Action

    SMP0000491

    Pw000467 View Pathway
    Metabolite

    Sepiapterin Reductase Deficiency

    Homo sapiens

  • Matched Description: gene. This gene is responsible for Sepiapterin production, and naturally, when the gene … case, some symptoms of Sepiapterin Deficiency are: motor and speech delay, axial hypotonia, dystonia

  • Disease