3-Hydroxy-3-methylglutaryl-coenzyme A reductase
Promoter + Sterol regulatory element-binding protein 1 → Sterol regulatory element-binding protein 1 (Homo sapiens) + Promoter
Low-density lipoprotein receptor → Low-density lipoprotein receptor
Membrane-bound transcription factor site-1 protease
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
Membrane-bound transcription factor site-2 protease
Sterol regulatory element-binding protein 1
Sterol regulatory element-binding protein cleavage-activating protein
Coenzyme A + Mevalonic acid + 2 NADP ← 3-Hydroxy-3-methylglutaryl-CoA + 2 Hydrogen Ion + 2 NADPH
Acetoacetyl-CoA + Acetyl-CoA + Water → 3-Hydroxy-3-methylglutaryl-CoA + Coenzyme A + Hydrogen Ion
2 Acetyl-CoA ↔ Acetoacetyl-CoA + Coenzyme A
Solute carrier organic anion transporter family member 1B1
INSIG/SCAP/SREBF → Insulin-induced gene 1 protein + SCAP/SREBF
SCAP/SREBF → Sterol regulatory element-binding protein 1 + Sterol regulatory element-binding protein cleavage-activating protein
Sterol regulatory element-binding protein 1 (Homo sapiens)_Promoter
Low-density lipoprotein receptor (→) Transport: Homo sapiens, Cell, Nucleoplasm to Homo sapiens, Cell, Cell Membrane
Sterol regulatory element-binding protein 1 (→) Transport: Homo sapiens, Cell, Cytoplasm to Homo sapiens, Cell, Nucleoplasm
Atorvastatin (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytoplasm
SCAP/SREBF (→) Transport: Homo sapiens, Cell, Endoplasmic Reticulum Membrane to Homo sapiens, Cell, Golgi Apparatus Membrane
Atorvastatin inhibits 3-Hydroxy-3-methylglutaryl-coenzyme A reductase