Phosphatidylcholine:ceramide cholinephosphotransferase 1
Adenosine diphosphate + Sphinganine 1-phosphate → Adenosine triphosphate + Sphinganine
Sphinganine 1-phosphate + Water → Phosphate + Sphinganine
NADPH + Sphinganine → 3-Dehydrosphinganine + NADP
L-Serine + Palmitoyl-CoA → 3-Dehydrosphinganine + Carbon dioxide
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
Adenosine triphosphate + Ceramide (d18:1/18:0) → Adenosine diphosphate + CerP(d18:1/18:0)
Phosphate + Sphingosine → Sphingosine 1-phosphate + Water
Ceramide (d18:1/18:0) + Water → Sphingosine
Adenosine triphosphate + Sphingosine → Adenosine diphosphate + Sphingosine 1-phosphate
Adenosine diphosphate + Sphingosine 1-phosphate → Adenosine triphosphate + Sphingosine
Sphingosine 1-phosphate → O-Phosphoethanolamine + Palmitaldehyde
3-O-Sulfogalactosylceramide (d18:1/18:0)
Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
N-Acetylneuraminyl-galactosylceramide (d18:1/18:0)
Adenosine triphosphate + Sphinganine → Adenosine diphosphate + Sphinganine 1-phosphate
Sphinganine 1-phosphate → O-Phosphoethanolamine + Palmitaldehyde
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
Lactosylceramide (d18:1/18:0) → Glucosylceramide (d18:1/18:0)
Galabiosylceramide (d18:1/18:0) + Phosphoadenosine phosphosulfate → Adenosine 3',5'-diphosphate + Galabiosylceramide sulfate (d18:1/18:0)
Ceramide (d18:1/18:0) + Uridine diphosphate glucose → Glucosylceramide (d18:1/18:0) + Uridine 5'-diphosphate
Glucosylceramide (d18:1/18:0) + Water → Ceramide (d18:1/18:0) + D-Glucose
Galactosylceramide (d18:1/18:0) → Ceramide (d18:1/18:0)
SM(d18:1/18:0) + Water → Ceramide (d18:1/18:0) + Phosphorylcholine
Ceramide (d18:1/18:0) → Galactosylceramide (d18:1/18:0)
CerP(d18:1/18:0) + Water → Ceramide (d18:1/18:0) + Phosphate
Lactosylceramide (d18:1/18:0) + Uridine 5'-diphosphate ← Glucosylceramide (d18:1/18:0) + Uridine diphosphate glucose
Galactosylceramide (d18:1/18:0) → N-Acetylneuraminyl-galactosylceramide (d18:1/18:0)
D-Galactose + Galactosylceramide (d18:1/18:0) ← Galabiosylceramide (d18:1/18:0)
Galactosylceramide (d18:1/18:0) + Phosphoadenosine phosphosulfate → 3-O-Sulfogalactosylceramide (d18:1/18:0) + Adenosine 3',5'-diphosphate
3-O-Sulfogalactosylceramide (d18:1/18:0) + Water → Galactosylceramide (d18:1/18:0) + Sulfate