Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/CAS 74465-19-3
type: UnificationXref
id: 74465-19-3
db: CAS

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Inositol 1,3,4,5,6-pentakisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16322
xref: Reference/CAS 20298-95-7
xref: Reference/KEGG Compound C01284
xref: Reference/ChemSpider 10333900
xref: Reference/HMDB HMDB0003529
chemical formula: C6H17O21P5
molecular weight: 579.895
structure: ChemicalStructure/PW C001912

Reaction1372
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000137 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002944 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: myo-Inositol
spontaneous: false
left: 1D-myo-Inositol 3-phosphate
left: Water
name: 1D-myo-Inositol 3-phosphate + Water → Phosphate + myo-Inositol
conversion direction: LEFT_TO_RIGHT

Compound/PW C001912 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5,6-pentakisphosphate
stoichiometric coefficient: 1.0

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001155 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
right: Inositol 1,3,4,5-tetraphosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.151
left: Inositol 1,4,5-trisphosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + Inositol 1,4,5-trisphosphate → Adenosine diphosphate + Inositol 1,3,4,5-tetraphosphate
conversion direction: LEFT_TO_RIGHT

Inositol hexakisphosphate kinase 1
type: Protein
cellular location: Cytosol
entity reference: Inositol hexakisphosphate kinase 1

3.1.3.66
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002678 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: 1D-Myo-inositol 1,3-bisphosphate
spontaneous: false
EC number: 3.1.3.66
left: Inositol 1,3,4-trisphosphate
left: Water
name: Inositol 1,3,4-trisphosphate + Water → 1D-Myo-inositol 1,3-bisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt O15327
type: UnificationXref
id: O15327
db: UniProt

Reference/UniProt P29218
type: UnificationXref
id: P29218
db: UniProt

2.7.1.158
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001908 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Myo-inositol hexakisphosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.158
left: Adenosine triphosphate
left: Inositol 1,3,4,5,6-pentakisphosphate
name: Adenosine triphosphate + Inositol 1,3,4,5,6-pentakisphosphate → Adenosine diphosphate + Myo-inositol hexakisphosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 391520
type: UnificationXref
id: 391520
db: ChemSpider

2.7.1.127
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001155 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5-tetraphosphate
spontaneous: false
EC number: 2.7.1.127
left: Adenosine triphosphate
left: Inositol 1,4,5-trisphosphate
name: Adenosine triphosphate + Inositol 1,4,5-trisphosphate → Adenosine diphosphate + Inositol 1,3,4,5-tetraphosphate
conversion direction: LEFT_TO_RIGHT

Reaction1137
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001980 Cytosol/Stoichiometry/1.0
right: Adenosine triphosphate
right: D-Myo-inositol 3,4,5,6-tetrakisphosphate
spontaneous: false
left: Adenosine diphosphate
left: Inositol 1,3,4,5,6-pentakisphosphate
name: Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate → Adenosine triphosphate + D-Myo-inositol 3,4,5,6-tetrakisphosphate
conversion direction: LEFT_TO_RIGHT

Reaction1376
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001012 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000137 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: myo-Inositol
spontaneous: false
left: D-Myo-inositol 4-phosphate
left: Water
name: D-Myo-inositol 4-phosphate + Water → Phosphate + myo-Inositol
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0001187
type: UnificationXref
id: HMDB0001187
db: HMDB

Reaction1377
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000137 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000139 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: myo-Inositol
spontaneous: false
left: Myo-inositol 1-phosphate
left: Water
name: Myo-inositol 1-phosphate + Water → Phosphate + myo-Inositol
conversion direction: LEFT_TO_RIGHT

Inositol 1,3,4,5-tetraphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 107758
xref: Reference/HMDB HMDB0001059
xref: Reference/KEGG Compound C01272
xref: Reference/ChemSpider 96919
xref: Reference/CAS 102850-29-3
xref: Reference/ChEBI CHEBI 16783
xref: Reference/BioCyc CPD-506
chemical formula: C6H16O18P4
molecular weight: 499.9287
structure: ChemicalStructure/PW C000834

Reference/PathWhiz PW000055
type: UnificationXref
id: PW000055
db: PathWhiz

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reaction1362
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001908 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Inositol 1,3,4,5,6-pentakisphosphate
spontaneous: false
left: Myo-inositol hexakisphosphate
left: Water
name: Myo-inositol hexakisphosphate + Water → Inositol 1,3,4,5,6-pentakisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Adenosine diphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Adenosine diphosphate

Reference/ChemSpider 17216102
type: UnificationXref
id: 17216102
db: ChemSpider

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000923 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5,6-pentakisphosphate
spontaneous: false
EC number: 2.7.1.151
left: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate
left: Adenosine triphosphate
name: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate + Adenosine triphosphate → Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5,6-pentakisphosphate
spontaneous: false
EC number: 2.7.1.151
left: Adenosine triphosphate
left: Inositol 1,3,4,5-tetraphosphate
name: Adenosine triphosphate + Inositol 1,3,4,5-tetraphosphate → Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate
conversion direction: LEFT_TO_RIGHT

1D-Myo-inositol 1,3,4,6-tetrakisphosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 17216082
xref: Reference/CAS 110298-84-5
xref: Reference/BioCyc CPD-505
xref: Reference/HMDB HMDB0001187
xref: Reference/KEGG Compound C04477
xref: Reference/ChEBI CHEBI 16155
chemical formula: C6H16O18P4
molecular weight: 499.9287
structure: ChemicalStructure/PW C000923

Reference/ChemSpider 5743
type: UnificationXref
id: 5743
db: ChemSpider

Reference/BRENDA TISSUE ONTOLOGY BTO 0000759
type: UnificationXref
id: BTO:0000759
db: BRENDA TISSUE ONTOLOGY

Inositol monophosphatase 1
type: Protein
cellular location: Cytosol
entity reference: Inositol monophosphatase 1

Reference/PathWhiz PW000168
type: UnificationXref
id: PW000168
db: PathWhiz

Reference/UniProt Q92551
type: UnificationXref
id: Q92551
db: UniProt

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Compound/PW C000139 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Myo-inositol 1-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16595
type: UnificationXref
id: CHEBI:16595
db: ChEBI

Reference/BioCyc MYO-INOSITOL
type: UnificationXref
id: MYO-INOSITOL
db: BioCyc

Reference/ChemSpider 17216357
type: UnificationXref
id: 17216357
db: ChemSpider

5.5.1.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002944 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001083 Cytosol/Stoichiometry/1.0
right: 1D-myo-Inositol 3-phosphate
spontaneous: false
EC number: 5.5.1.4
left: Glucose 6-phosphate
name: Glucose 6-phosphate → 1D-myo-Inositol 3-phosphate
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C001083
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis842
type: Catalysis
controller: Type I inositol 3,4-bisphosphate 4-phosphatase
controlled: 3.1.3.66
control type: ACTIVATION

3.1.3.56
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000772 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001155 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: 1D-Myo-inositol 1,4-bisphosphate
spontaneous: false
EC number: 3.1.3.56
left: Inositol 1,4,5-trisphosphate
left: Water
name: Inositol 1,4,5-trisphosphate + Water → 1D-Myo-inositol 1,4-bisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PathWhiz PW000156
type: UnificationXref
id: PW000156
db: PathWhiz

Myo-inositol hexakisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003502
xref: Reference/ChEBI CHEBI 17401
xref: Reference/CAS 83-86-3
xref: Reference/BioCyc MI-HEXAKISPHOSPHATE
xref: Reference/KEGG Compound C01204
xref: Reference/PubChem-compound 890
xref: Reference/ChemSpider 866
chemical formula: C6H18O24P6
molecular weight: 659.8614
structure: ChemicalStructure/PW C001908

Reference/PathWhiz PW000159
type: UnificationXref
id: PW000159
db: PathWhiz

Reference/UniProt Q9H8X2
type: UnificationXref
id: Q9H8X2
db: UniProt

1D-myo-Inositol 3-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-myo-Inositol 3-phosphate

Compound/PW C001034 Nucleus/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 2.0

Compound/PW C001083 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000150
type: UnificationXref
id: PW000150
db: PathWhiz

3.1.3.56
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Inositol 1,3,4-trisphosphate
spontaneous: false
EC number: 3.1.3.56
left: Inositol 1,3,4,5-tetraphosphate
left: Water
name: Inositol 1,3,4,5-tetraphosphate + Water → Inositol 1,3,4-trisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C001912 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5,6-pentakisphosphate
stoichiometric coefficient: 1.0

Reaction1140
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000834 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001155 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Endoplasmic Reticulum/Stoichiometry/1.0
right: Inositol 1,4,5-trisphosphate
right: Phosphate
spontaneous: false
left: Water
left: Inositol 1,3,4,5-tetraphosphate
name: Inositol 1,3,4,5-tetraphosphate + Water → Inositol 1,4,5-trisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis838
type: Catalysis
controller: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
controlled: 3.1.3.56
control type: ACTIVATION

ReactionCatalysis839
type: Catalysis
controller: Inositol-tetrakisphosphate 1-kinase
controlled: Reaction1145
control type: ACTIVATION

ReactionCatalysis834
type: Catalysis
controller: Multiple inositol polyphosphate phosphatase 1
controlled: Reaction1140
control type: ACTIVATION

ReactionCatalysis832
type: Catalysis
controller: Inositol-pentakisphosphate 2-kinase
controlled: 2.7.1.158
control type: ACTIVATION

ReactionCatalysis833
type: Catalysis
controller: Inositol-trisphosphate 3-kinase A
controlled: 2.7.1.127
control type: ACTIVATION

3.1.3.66
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002679 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002944 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: 1D-myo-Inositol 3-phosphate
spontaneous: false
EC number: 3.1.3.66
left: 1D-Myo-inositol 3,4-bisphosphate
left: Water
name: 1D-Myo-inositol 3,4-bisphosphate + Water → 1D-myo-Inositol 3-phosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Reaction1145
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5-tetraphosphate
spontaneous: false
left: Inositol 1,3,4-trisphosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + Inositol 1,3,4-trisphosphate → Adenosine diphosphate + Inositol 1,3,4,5-tetraphosphate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis831
type: Catalysis
controller: Inositol-tetrakisphosphate 1-kinase
controlled: Reaction1137
control type: ACTIVATION

Compound/PW C000834 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5-tetraphosphate
stoichiometric coefficient: 1.0

Inositol 1,3,4,5,6-pentakisphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Inositol 1,3,4,5,6-pentakisphosphate

Reference/ChEBI CHEBI 17268
type: UnificationXref
id: CHEBI:17268
db: ChEBI

Reference/ChemSpider 10239179
type: UnificationXref
id: 10239179
db: ChemSpider

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

ReactionCatalysis1081
type: Catalysis
controller: Multiple inositol polyphosphate phosphatase 1
controlled: Reaction1362
control type: ACTIVATION

ReactionCatalysis1083
type: Catalysis
controller: Inositol polyphosphate multikinase
controlled: 2.7.1.151
control type: ACTIVATION

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/KEGG Compound C01204
type: UnificationXref
id: C01204
db: KEGG Compound

ChemicalStructure/PW C000923
type: ChemicalStructure
structure format: SMILES

Multiple inositol polyphosphate phosphatase 1
type: Protein
cellular location: Endoplasmic Reticulum
entity reference: Multiple inositol polyphosphate phosphatase 1

1D-Myo-inositol 1,3,4,6-tetrakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate

Reference/CAS 7664-38-2
type: UnificationXref
id: 7664-38-2
db: CAS

ReactionCatalysis1084
type: Catalysis
controller: Inositol polyphosphate multikinase
controlled: 2.7.1.151
control type: ACTIVATION

Reference/BioCyc 1-L-MYO-INOSITOL-1-P
type: UnificationXref
id: 1-L-MYO-INOSITOL-1-P
db: BioCyc

ReactionCatalysis1087
type: Catalysis
controller: Inositol polyphosphate multikinase
controlled: 2.7.1.151
control type: ACTIVATION

ReactionCatalysis1086
type: Catalysis
controller: Inositol polyphosphate multikinase
controlled: 2.7.1.151
control type: ACTIVATION

Reference/BioCyc inositol 1,4,5-trisphosphate
type: UnificationXref
id: inositol_1,4,5-trisphosphate
db: BioCyc

ReactionCatalysis1089
type: Catalysis
controller: Inositol polyphosphate multikinase
controlled: 2.7.1.151
control type: ACTIVATION

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

ChemicalStructure/PW C001908
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

ReactionCatalysis1090
type: Catalysis
controller: Type II inositol 3,4-bisphosphate 4-phosphatase
controlled: 3.1.3.66
control type: ACTIVATION

ReactionCatalysis1092
type: Catalysis
controller: Inositol monophosphatase 1
controlled: Reaction1372
control type: ACTIVATION

1D-Myo-inositol 1,4,5,6-tetrakisphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate

ReactionCatalysis1091
type: Catalysis
controller: Inositol polyphosphate 1-phosphatase
controlled: 3.1.3.57
control type: ACTIVATION

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Compound/PW C001034 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Compound/PW C002147 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/ChemSpider 388561
type: UnificationXref
id: 388561
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChEBI CHEBI 16067
type: UnificationXref
id: CHEBI:16067
db: ChEBI

Reference/ChemSpider 388562
type: UnificationXref
id: 388562
db: ChemSpider

Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
type: ProteinReference
xref: Reference/UniProt Q15735
organism: Homo sapiens

Inositol polyphosphate 1-phosphatase
type: ProteinReference
xref: Reference/UniProt P49441
organism: Homo sapiens

Type I inositol 3,4-bisphosphate 4-phosphatase
type: Protein
cellular location: Cytosol
entity reference: Type I inositol 3,4-bisphosphate 4-phosphatase

ReactionCatalysis1096
type: Catalysis
controller: Inositol monophosphatase 1
controlled: Reaction1376
control type: ACTIVATION

ReactionCatalysis1097
type: Catalysis
controller: Inositol monophosphatase 1
controlled: Reaction1377
control type: ACTIVATION

SubPathwayInteraction221
type: Interaction
name: SubPathwayReaction
name: SubPathway221Reaction
participant: Glucose 6-phosphate

Compound/PW C000414 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 2.0

Reference/KEGG Compound C01220
type: UnificationXref
id: C01220
db: KEGG Compound

Reference/KEGG Compound C00137
type: UnificationXref
id: C00137
db: KEGG Compound

Reference/ChEBI CHEBI 16155
type: UnificationXref
id: CHEBI:16155
db: ChEBI

Compound/PW C000414 Nucleus/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 2.0

Reference/CAS 83-86-3
type: UnificationXref
id: 83-86-3
db: CAS

Reference/ChEBI CHEBI 18228
type: UnificationXref
id: CHEBI:18228
db: ChEBI

Compound/PW C002678 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,3-bisphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18225
type: UnificationXref
id: CHEBI:18225
db: ChEBI

Reference/BioCyc CPD-3841
type: UnificationXref
id: CPD-3841
db: BioCyc

Compound/PW C001155 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,4,5-trisphosphate
stoichiometric coefficient: 1.0

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 102850-29-3
type: UnificationXref
id: 102850-29-3
db: CAS

Reference/ChEBI CHEBI 26078
type: UnificationXref
id: CHEBI:26078
db: ChEBI

Compound/PW C002679 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 3,4-bisphosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0006229
type: UnificationXref
id: HMDB0006229
db: HMDB

Reference/PubChem-compound 440194
type: UnificationXref
id: 440194
db: PubChem-compound

Reference/ChemSpider 26333173
type: UnificationXref
id: 26333173
db: ChemSpider

Reference/CAS 110298-84-5
type: UnificationXref
id: 110298-84-5
db: CAS

Reference/KEGG Compound C01243
type: UnificationXref
id: C01243
db: KEGG Compound

Reference/KEGG Compound C03546
type: UnificationXref
id: C03546
db: KEGG Compound

Reference/PubChem-compound 443266
type: UnificationXref
id: 443266
db: PubChem-compound

Reference/ChEBI CHEBI 30164
type: UnificationXref
id: CHEBI:30164
db: ChEBI

Reference/KEGG Compound C01245
type: UnificationXref
id: C01245
db: KEGG Compound

Compound/PW C000414 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Inositol polyphosphate 1-phosphatase
type: Protein
cellular location: Cytosol
entity reference: Inositol polyphosphate 1-phosphatase

Reference/ChemSpider 16744067
type: UnificationXref
id: 16744067
db: ChemSpider

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/UniProt Q9UNW1
type: UnificationXref
id: Q9UNW1
db: UniProt

Reference/HMDB HMDB0003529
type: UnificationXref
id: HMDB0003529
db: HMDB

Reference/KEGG Compound C04520
type: UnificationXref
id: C04520
db: KEGG Compound

Inositol-3-phosphate synthase 1
type: Protein
cellular location: Cytosol
entity reference: Inositol-3-phosphate synthase 1

Reference/ChEBI CHEBI 18169
type: UnificationXref
id: CHEBI:18169
db: ChEBI

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001155
type: ChemicalStructure
structure format: SMILES

1D-Myo-inositol 3,4-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 3,4-bisphosphate

Reference/UniProt Q8NFU5
type: UnificationXref
id: Q8NFU5
db: UniProt

SubPathwayInteraction211
type: Interaction
name: SubPathway211Reaction
name: SubPathwayReaction
participant: Inositol 1,4,5-trisphosphate

SubPathwayInteraction217
type: Interaction
name: SubPathway217Reaction
name: SubPathwayReaction
participant: myo-Inositol

SubPathwayInteraction218
type: Interaction
name: SubPathwayReaction
name: SubPathway218Reaction
participant: Glucose 6-phosphate

Reference/CAS 46495-39-0
type: UnificationXref
id: 46495-39-0
db: CAS

SubPathwayInteraction219
type: Interaction
name: SubPathway219Reaction
name: SubPathwayReaction
participant: Glucose 6-phosphate

1D-myo-Inositol 3-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0006814
xref: Reference/CAS 2831-74-5
xref: Reference/ChemSpider 389182
xref: Reference/PubChem-compound 440194
xref: Reference/KEGG Compound C04006
xref: Reference/ChEBI CHEBI 18169
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C002944

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChEBI CHEBI 4170
type: UnificationXref
id: CHEBI:4170
db: ChEBI

Compound/PW C001420 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/UniProt P49441
type: UnificationXref
id: P49441
db: UniProt

Reference/HMDB HMDB0006814
type: UnificationXref
id: HMDB0006814
db: HMDB

Water
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Water

D-Myo-inositol 3,4,5,6-tetrakisphosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 108765
xref: Reference/PubChem-compound 121920
xref: Reference/ChEBI CHEBI 15844
xref: Reference/HMDB HMDB0003848
xref: Reference/KEGG Compound C04520
xref: Reference/CAS 112791-61-4
chemical formula: C6H16O18P4
molecular weight: 499.9287
structure: ChemicalStructure/PW C001980

Reference/KEGG Compound C01272
type: UnificationXref
id: C01272
db: KEGG Compound

Compound/PW C001104 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

1D-Myo-inositol 1,4-bisphosphate
type: SmallMoleculeReference
xref: Reference/CAS 74465-19-3
xref: Reference/BioCyc INOSITOL-1,4-BISPHOSPHATE
xref: Reference/ChemSpider 17216032
xref: Reference/KEGG Compound C01220
xref: Reference/HMDB HMDB0000968
xref: Reference/ChEBI CHEBI 17816
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C000772

Inositol 1,3,4-trisphosphate
type: SmallMoleculeReference
xref: Reference/CAS 98102-63-7
xref: Reference/BioCyc INOSITOL-1-3-4-TRIPHOSPHATE
xref: Reference/PubChem-compound 439455
xref: Reference/ChEBI CHEBI 18228
xref: Reference/KEGG Compound C01243
xref: Reference/ChemSpider 388561
xref: Reference/HMDB HMDB0001143
chemical formula: C6H15O15P3
molecular weight: 419.96237
structure: ChemicalStructure/PW C000892

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Phosphoric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphoric acid

BiologicalState10
type: BioSource
xref: Reference/TAXONOMY 9606
name: Homo sapiens, Liver
tissue: Liver

Reference/ChEBI CHEBI 18384
type: UnificationXref
id: CHEBI:18384
db: ChEBI

Inositol 1,4,5-trisphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Inositol 1,4,5-trisphosphate

Reference/PubChem-compound 892
type: UnificationXref
id: 892
db: PubChem-compound

Reference/PubChem-compound 890
type: UnificationXref
id: 890
db: PubChem-compound

1D-Myo-inositol 1,4,5,6-tetrakisphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate

Reference/HMDB HMDB0001498
type: UnificationXref
id: HMDB0001498
db: HMDB

ChemicalStructure/PW C001012
type: ChemicalStructure
structure format: SMILES

Compound/PW C002147 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C01284
type: UnificationXref
id: C01284
db: KEGG Compound

Reference/HMDB HMDB0004527
type: UnificationXref
id: HMDB0004527
db: HMDB

Compound/PW C000923 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Compound/PW C002944 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-myo-Inositol 3-phosphate
stoichiometric coefficient: 1.0

Inositol-trisphosphate 3-kinase A
type: Protein
cellular location: Cytosol
entity reference: Inositol-trisphosphate 3-kinase A

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/ChemSpider 979
type: UnificationXref
id: 979
db: ChemSpider

Compound/PW C001980 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Myo-inositol 3,4,5,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Phosphoric acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/ChEBI CHEBI 26078
xref: Reference/CAS 7664-38-2
xref: Reference/PubChem-compound 1004
xref: Reference/ChemSpider 979
xref: Reference/HMDB HMDB0002142
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001441

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0001143
type: UnificationXref
id: HMDB0001143
db: HMDB

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/KEGG Compound C00092
type: UnificationXref
id: C00092
db: KEGG Compound

Compound/PW C001104 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Compound/PW C000772 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,4-bisphosphate
stoichiometric coefficient: 1.0

Myo-inositol hexakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Myo-inositol hexakisphosphate

Inositol-tetrakisphosphate 1-kinase
type: ProteinReference
xref: Reference/UniProt Q13572
organism: Homo sapiens

Multiple inositol polyphosphate phosphatase 1
type: ProteinReference
xref: Reference/UniProt Q9UNW1
organism: Homo sapiens

Reference/UniProt Q9NPH2
type: UnificationXref
id: Q9NPH2
db: UniProt

Reference/CAS 56-73-5
type: UnificationXref
id: 56-73-5
db: CAS

1D-Myo-inositol 1,3-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 1,3-bisphosphate

Compound/PW C001441 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoric acid
stoichiometric coefficient: 1.0

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Nucleus
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005634

Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
type: Protein
cellular location: Cytosol
entity reference: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 866
type: UnificationXref
id: 866
db: ChemSpider

Adenosine triphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Adenosine triphosphate

ChemicalStructure/PW C002147
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001059
type: UnificationXref
id: HMDB0001059
db: HMDB

Inositol 1,4,5-trisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Inositol 1,4,5-trisphosphate
name: SubPathwayOutput

Reference/HMDB HMDB0002142
type: UnificationXref
id: HMDB0002142
db: HMDB

Compound/PW C002676 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5-Diphosphoinositol pentakisphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 17215924
type: UnificationXref
id: 17215924
db: ChemSpider

Reference/ChEBI CHEBI 15844
type: UnificationXref
id: CHEBI:15844
db: ChEBI

Reference/KEGG Compound C04477
type: UnificationXref
id: C04477
db: KEGG Compound

D-Myo-inositol 4-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Myo-inositol 4-phosphate

Pentose Phosphate Pathway
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway221
pathway component: SubPathwayInteraction221
xref: Reference/PathWhiz PW000055
xref: Reference/SMPDB SMP0000031
name: SubPathway

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Inositol polyphosphate multikinase
type: Protein
cellular location: Nucleus
entity reference: Inositol polyphosphate multikinase

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
type: Protein
cellular location: Cytosol
entity reference: Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

Inositol polyphosphate multikinase
type: ProteinReference
xref: Reference/UniProt Q8NFU5
organism: Homo sapiens

Diphosphoinositol polyphosphate phosphohydrolase 1
type: Protein
cellular location: Cytosol
entity reference: Diphosphoinositol polyphosphate phosphohydrolase 1

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/KEGG Compound C04006
type: UnificationXref
id: C04006
db: KEGG Compound

Reference/PubChem-compound 1004
type: UnificationXref
id: 1004
db: PubChem-compound

Multiple inositol polyphosphate phosphatase 1
type: Protein
cellular location: Cytosol
entity reference: Multiple inositol polyphosphate phosphatase 1

Galactose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway218
pathway component: SubPathwayInteraction218
xref: Reference/PathWhiz PW000159
xref: Reference/SMPDB SMP0000043
name: SubPathway

Compound/PW C002147 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Inositol 1,3,4-trisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Inositol 1,3,4-trisphosphate

Type II inositol 3,4-bisphosphate 4-phosphatase
type: Protein
cellular location: Cytosol
entity reference: Type II inositol 3,4-bisphosphate 4-phosphatase

D-Myo-inositol 4-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001313
xref: Reference/ChEBI CHEBI 18384
xref: Reference/CAS 46495-39-0
xref: Reference/ChemSpider 17216102
xref: Reference/KEGG Compound C03546
xref: Reference/BioCyc D-MYO-INOSITOL-4-PHOSPHATE
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001012

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Diphosphoinositol polyphosphate phosphohydrolase 1
type: ProteinReference
xref: Reference/UniProt O95989
organism: Homo sapiens

Reference/BioCyc INOSITOL-1-3-4-TRIPHOSPHATE
type: UnificationXref
id: INOSITOL-1-3-4-TRIPHOSPHATE
db: BioCyc

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/HMDB HMDB0001401
type: UnificationXref
id: HMDB0001401
db: HMDB

Reference/ChemSpider 108765
type: UnificationXref
id: 108765
db: ChemSpider

Compound/PW C001155 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,4,5-trisphosphate
stoichiometric coefficient: 1.0

5-Diphosphoinositol pentakisphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C11526
xref: Reference/HMDB HMDB0006229
xref: Reference/ChemSpider 17216357
xref: Reference/ChEBI CHEBI 30164
chemical formula: C6H19O27P7
molecular weight: 739.8277
structure: ChemicalStructure/PW C002676

Reference/CAS 85166-31-0
type: UnificationXref
id: 85166-31-0
db: CAS

Inositol 1,3,4,5-tetraphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Inositol 1,3,4,5-tetraphosphate

Starch and Sucrose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway219
pathway component: SubPathwayInteraction219
xref: Reference/SMPDB SMP0000058
xref: Reference/PathWhiz PW000150
name: SubPathway

Myo-inositol 1-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000213
xref: Reference/ChemSpider 17215924
xref: Reference/CAS 2831-74-5
xref: Reference/KEGG Compound C04006
xref: Reference/BioCyc 1-L-MYO-INOSITOL-1-P
xref: Reference/ChEBI CHEBI 18169
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000139

myo-Inositol
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000211
xref: Reference/ChEBI CHEBI 17268
xref: Reference/ChemSpider 10239179
xref: Reference/CAS 87-89-8
xref: Reference/BioCyc MYO-INOSITOL
xref: Reference/KEGG Compound C00137
xref: Reference/PubChem-compound 892
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000137

Bisdiphosphoinositol tetrakisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 52965
xref: Reference/BioCyc CPD-3841
xref: Reference/PubChem-compound 25245165
xref: Reference/HMDB HMDB0006230
xref: Reference/ChemSpider 26333173
chemical formula: C6H20O30P8
molecular weight: 819.794
structure: ChemicalStructure/PW C002677

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

1D-Myo-inositol 1,3-bisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18225
xref: Reference/CAS 103597-56-4
xref: Reference/KEGG Compound C04062
xref: Reference/HMDB HMDB0006234
xref: Reference/BioCyc 5-DIPHOSPHO-1D-MYO-INOSITOL-12346P
xref: Reference/ChemSpider 16744067
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C002678

1D-Myo-inositol 3,4-bisphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440211
xref: Reference/BioCyc PHOSPHATIDYLINOSITOL-345-TRIPHOSPHATE
xref: Reference/KEGG Compound C04063
xref: Reference/ChEBI CHEBI 28858
xref: Reference/HMDB HMDB0006235
xref: Reference/CAS 69256-53-7
xref: Reference/ChemSpider 389196
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C002679

ReactionCatalysis1117
type: Catalysis
controller: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
controlled: 3.1.3.56
control type: ACTIVATION

ReactionCatalysis1116
type: Catalysis
controller: Inositol-3-phosphate synthase 1
controlled: 5.5.1.4
control type: ACTIVATION

ReactionCatalysis1118
type: Catalysis
controller: Inositol polyphosphate 1-phosphatase
controlled: 3.1.3.57
control type: ACTIVATION

Reference/PubChem-compound 25245165
type: UnificationXref
id: 25245165
db: PubChem-compound

Reference/PubChem-compound 121920
type: UnificationXref
id: 121920
db: PubChem-compound

Reference/ChemSpider 10333900
type: UnificationXref
id: 10333900
db: ChemSpider

Reference/CAS 87-89-8
type: UnificationXref
id: 87-89-8
db: CAS

Type II inositol 3,4-bisphosphate 4-phosphatase
type: ProteinReference
xref: Reference/UniProt O15327
organism: Homo sapiens

Bisdiphosphoinositol tetrakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Bisdiphosphoinositol tetrakisphosphate

Compound/PW C001155 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,4,5-trisphosphate
stoichiometric coefficient: 1.0

myo-Inositol
type: SmallMolecule
cellular location: Cytosol
entity reference: myo-Inositol
name: SubPathwayInput

Reference/HMDB HMDB0000211
type: UnificationXref
id: HMDB0000211
db: HMDB

ChemicalStructure/PW C002676
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000213
type: UnificationXref
id: HMDB0000213
db: HMDB

ChemicalStructure/PW C002677
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/UniProt P23677
type: UnificationXref
id: P23677
db: UniProt

Compound/PW C002677 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Bisdiphosphoinositol tetrakisphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17816
type: UnificationXref
id: CHEBI:17816
db: ChEBI

Inositol-pentakisphosphate 2-kinase
type: Protein
cellular location: Cytosol
entity reference: Inositol-pentakisphosphate 2-kinase

Reference/SMPDB SMP0000043
type: UnificationXref
id: SMP0000043
db: SMPDB

Reference/CAS 2831-74-5
type: UnificationXref
id: 2831-74-5
db: CAS

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

ChemicalStructure/PW C000139
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0003848
type: UnificationXref
id: HMDB0003848
db: HMDB

ChemicalStructure/PW C000137
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002678
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc D-MYO-INOSITOL-4-PHOSPHATE
type: UnificationXref
id: D-MYO-INOSITOL-4-PHOSPHATE
db: BioCyc

ChemicalStructure/PW C002679
type: ChemicalStructure
structure format: SMILES

Liver
type: TissueVocabulary
xref: Reference/BRENDA TISSUE ONTOLOGY BTO 0000759

Reference/HMDB HMDB0001313
type: UnificationXref
id: HMDB0001313
db: HMDB

1D-Myo-inositol 1,4,5,6-tetrakisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0004527
xref: Reference/CAS 121010-58-0
xref: Reference/ChemSpider 391520
xref: Reference/PubChem-compound 443266
xref: Reference/KEGG Compound C11555
xref: Reference/ChEBI CHEBI 16067
chemical formula: C6H16O18P4
molecular weight: 499.9287
structure: ChemicalStructure/PW C002147

Reference/CAS 121010-58-0
type: UnificationXref
id: 121010-58-0
db: CAS

Reference/SMPDB SMP0000058
type: UnificationXref
id: SMP0000058
db: SMPDB

Reference/GENE ONTOLOGY GO 0005634
type: UnificationXref
id: GO:0005634
db: GENE ONTOLOGY

Compound/PW C001908 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Myo-inositol hexakisphosphate
stoichiometric coefficient: 1.0

Reference/BioCyc PHOSPHATIDYLINOSITOL-345-TRIPHOSPHATE
type: UnificationXref
id: PHOSPHATIDYLINOSITOL-345-TRIPHOSPHATE
db: BioCyc

Inositol monophosphatase 1
type: ProteinReference
xref: Reference/UniProt P29218
organism: Homo sapiens

Inositol-trisphosphate 3-kinase A
type: ProteinReference
xref: Reference/UniProt P23677
organism: Homo sapiens

Inositol-3-phosphate synthase 1
type: ProteinReference
xref: Reference/UniProt Q9NPH2
organism: Homo sapiens

ChemicalStructure/PW C001441
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0003502
type: UnificationXref
id: HMDB0003502
db: HMDB

Reference/PubChem-compound 5958
type: UnificationXref
id: 5958
db: PubChem-compound

Reference/KEGG Compound C04063
type: UnificationXref
id: C04063
db: KEGG Compound

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/KEGG Compound C04062
type: UnificationXref
id: C04062
db: KEGG Compound

Reference/CAS 98102-63-7
type: UnificationXref
id: 98102-63-7
db: CAS

Reference/ChemSpider 389196
type: UnificationXref
id: 389196
db: ChemSpider

Compound/PW C000834 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5-tetraphosphate
stoichiometric coefficient: 1.0

Type I inositol 3,4-bisphosphate 4-phosphatase
type: ProteinReference
xref: Reference/UniProt Q96PE3
organism: Homo sapiens

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Inositol 1,4,5-trisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001498
xref: Reference/PubChem-compound 439456
xref: Reference/CAS 85166-31-0
xref: Reference/BioCyc inositol 1,4,5-trisphosphate
xref: Reference/KEGG Compound C01245
xref: Reference/ChEBI CHEBI 16595
xref: Reference/ChemSpider 388562
chemical formula: C6H15O15P3
molecular weight: 419.96237
structure: ChemicalStructure/PW C001155

Inositol 1,4,5-trisphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Inositol 1,4,5-trisphosphate

Compound/PW C000834 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5-tetraphosphate
stoichiometric coefficient: 1.0

Reference/UniProt Q96PE3
type: UnificationXref
id: Q96PE3
db: UniProt

Endoplasmic Reticulum
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005783

Inositol 1,3,4,5-tetraphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Inositol 1,3,4,5-tetraphosphate

Endoplasmic Reticulum Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005789

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

D-Myo-inositol 3,4,5,6-tetrakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Myo-inositol 3,4,5,6-tetrakisphosphate

Reference/HMDB HMDB0006234
type: UnificationXref
id: HMDB0006234
db: HMDB

Reference/HMDB HMDB0006235
type: UnificationXref
id: HMDB0006235
db: HMDB

Reference/HMDB HMDB0006230
type: UnificationXref
id: HMDB0006230
db: HMDB

Reference/UniProt Q15735
type: UnificationXref
id: Q15735
db: UniProt

Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00092
xref: Reference/BioCyc GLC-6-P
xref: Reference/HMDB HMDB0001401
xref: Reference/PubChem-compound 5958
xref: Reference/ChemSpider 5743
xref: Reference/CAS 56-73-5
xref: Reference/ChEBI CHEBI 4170
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001083

Reference/UniProt Q6PFW1
type: UnificationXref
id: Q6PFW1
db: UniProt

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
type: ProteinReference
xref: Reference/UniProt Q6PFW1
organism: Homo sapiens

Reference/ChEBI CHEBI 16783
type: UnificationXref
id: CHEBI:16783
db: ChEBI

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Water
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Water

Reference/CAS 103597-56-4
type: UnificationXref
id: 103597-56-4
db: CAS

Reference/ChemSpider 389182
type: UnificationXref
id: 389182
db: ChemSpider

Myo-inositol 1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Myo-inositol 1-phosphate

Reference/ChemSpider 96919
type: UnificationXref
id: 96919
db: ChemSpider

Reaction1404
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002147 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001912 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Phosphate
right: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
spontaneous: false
left: Water
left: Inositol 1,3,4,5,6-pentakisphosphate
name: Inositol 1,3,4,5,6-pentakisphosphate + Water → 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Phosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Phosphate

5-Diphosphoinositol pentakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 5-Diphosphoinositol pentakisphosphate

Homo sapiens
type: BioSource
xref: Reference/TAXONOMY 9606

Inositol hexakisphosphate kinase 1
type: ProteinReference
xref: Reference/UniProt Q92551
organism: Homo sapiens

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Inositol-pentakisphosphate 2-kinase
type: ProteinReference
xref: Reference/UniProt Q9H8X2
organism: Homo sapiens

ChemicalStructure/PW C001912
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 439455
type: UnificationXref
id: 439455
db: PubChem-compound

Reference/PubChem-compound 439456
type: UnificationXref
id: 439456
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005789
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

Multiple inositol polyphosphate phosphatase 1
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Multiple inositol polyphosphate phosphatase 1

Reference/GENE ONTOLOGY GO 0005783
type: UnificationXref
id: GO:0005783
db: GENE ONTOLOGY

ReactionCatalysis1069
type: Catalysis
controller: Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
controlled: Reaction1353
control type: ACTIVATION

ReactionCatalysis1068
type: Catalysis
controller: Diphosphoinositol polyphosphate phosphohydrolase 1
controlled: Reaction1352
control type: ACTIVATION

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/PubChem-compound 107758
type: UnificationXref
id: 107758
db: PubChem-compound

Compound/PW C000137 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: myo-Inositol
stoichiometric coefficient: 1.0

ReactionCatalysis1072
type: Catalysis
controller: Diphosphoinositol polyphosphate phosphohydrolase 1
controlled: Reaction1356
control type: ACTIVATION

Reference/UniProt O95989
type: UnificationXref
id: O95989
db: UniProt

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

ChemicalStructure/PW C000834
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 17216082
type: UnificationXref
id: 17216082
db: ChemSpider

Reference/BioCyc GLC-6-P
type: UnificationXref
id: GLC-6-P
db: BioCyc

Phosphatidylinositol Phosphate Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway211
pathway order: SubPathwayInteractionSteps/SubPathway217
pathway component: SubPathwayInteraction211
pathway component: SubPathwayInteraction217
xref: Reference/PathWhiz PW000168
xref: Reference/SMPDB SMP0000463
name: SubPathway

Inositol Phosphate Metabolism
type: Pathway
pathway order: PathwaySubPathway/211
pathway order: PathwayEnzymeReaction/211590
pathway order: PathwayEnzymeReaction/1493
pathway order: PathwayEnzymeReaction/1492
pathway order: PathwayEnzymeReaction/1491
pathway order: PathwaySubPathway/218
pathway order: PathwayEnzymeReaction/1490
pathway order: PathwaySubPathway/219
pathway order: PathwayEnzymeReaction/1453
pathway order: PathwayEnzymeReaction/1452
pathway order: PathwaySubPathway/217
pathway order: PathwayEnzymeReaction/1451
pathway order: PathwayEnzymeReaction/1495
pathway order: PathwayEnzymeReaction/1450
pathway order: PathwayEnzymeReaction/1446
pathway order: PathwayEnzymeReaction/1423
pathway order: PathwayEnzymeReaction/1445
pathway order: PathwayEnzymeReaction/1489
pathway order: PathwayEnzymeReaction/1443
pathway order: PathwayEnzymeReaction/1449
pathway order: PathwayEnzymeReaction/1426
pathway order: PathwayEnzymeReaction/1448
pathway order: PathwayEnzymeReaction/1447
pathway order: PathwaySubPathway/221
pathway order: PathwayEnzymeReaction/1420
pathway order: PathwayEnzymeReaction/1440
pathway order: PathwayEnzymeReaction/1434
pathway order: PathwayEnzymeReaction/1499
pathway order: PathwayEnzymeReaction/1439
pathway order: PathwayEnzymeReaction/1416
pathway order: PathwayEnzymeReaction/1415
pathway order: PathwayEnzymeReaction/1436
pathway component: ReactionCatalysis1081
pathway component: ReactionCatalysis1083
pathway component: Reaction1372
pathway component: Pentose Phosphate Pathway
pathway component: 2.7.1.151
pathway component: 3.1.3.66
pathway component: ReactionCatalysis1084
pathway component: 2.7.1.158
pathway component: ReactionCatalysis1087
pathway component: ReactionCatalysis1086
pathway component: 2.7.1.127
pathway component: ReactionCatalysis1089
pathway component: Reaction1137
pathway component: Reaction1376
pathway component: Reaction1377
pathway component: ReactionCatalysis1123
pathway component: ReactionCatalysis1090
pathway component: ReactionCatalysis1092
pathway component: ReactionCatalysis1091
pathway component: Galactose Metabolism
pathway component: Reaction1362
pathway component: ReactionCatalysis1096
pathway component: Reaction1404
pathway component: ReactionCatalysis1097
pathway component: Reaction1352
pathway component: Reaction1353
pathway component: Reaction1356
pathway component: 2.7.4.21
pathway component: ReactionCatalysis1069
pathway component: 5.5.1.4
pathway component: Starch and Sucrose Metabolism
pathway component: ReactionCatalysis1068
pathway component: ReactionCatalysis842
pathway component: 3.1.3.56
pathway component: ReactionCatalysis1072
pathway component: Reaction349
pathway component: Phosphatidylinositol Phosphate Metabolism
pathway component: ReactionCatalysis1117
pathway component: ReactionCatalysis1116
pathway component: Reaction1140
pathway component: ReactionCatalysis1118
pathway component: ReactionCatalysis838
pathway component: ReactionCatalysis839

Compound/PW C001034 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 28858
type: UnificationXref
id: CHEBI:28858
db: ChEBI

ReactionCatalysis1073
type: Catalysis
controller: Inositol hexakisphosphate kinase 1
controlled: 2.7.4.21
control type: ACTIVATION

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0000031
type: UnificationXref
id: SMP0000031
db: SMPDB

Reference/TAXONOMY 9606
type: UnificationXref
id: 9606
db: TAXONOMY

Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glucose 6-phosphate
name: SubPathwayOutput

Reference/HMDB HMDB0000968
type: UnificationXref
id: HMDB0000968
db: HMDB

ChemicalStructure/PW C002944
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001980
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C11526
type: UnificationXref
id: C11526
db: KEGG Compound

Inositol-tetrakisphosphate 1-kinase
type: Protein
cellular location: Cytosol
entity reference: Inositol-tetrakisphosphate 1-kinase

ChemicalStructure/PW C000772
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000892
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc 5-DIPHOSPHO-1D-MYO-INOSITOL-12346P
type: UnificationXref
id: 5-DIPHOSPHO-1D-MYO-INOSITOL-12346P
db: BioCyc

ReactionCatalysis1123
type: Catalysis
controller: Multiple inositol polyphosphate phosphatase 1
controlled: Reaction1404
control type: ACTIVATION

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

1D-Myo-inositol 1,4,5,6-tetrakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Reference/CAS 20298-95-7
type: UnificationXref
id: 20298-95-7
db: CAS

Reference/PubChem-compound 440211
type: UnificationXref
id: 440211
db: PubChem-compound

Inositol 1,3,4,5,6-pentakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Inositol 1,3,4,5,6-pentakisphosphate

Reference/BioCyc CPD-505
type: UnificationXref
id: CPD-505
db: BioCyc

Inositol 1,3,4,5-tetraphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Inositol 1,3,4,5-tetraphosphate

Phosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Phosphate

Reference/BioCyc CPD-506
type: UnificationXref
id: CPD-506
db: BioCyc

Inositol polyphosphate multikinase
type: Protein
cellular location: Cytosol
entity reference: Inositol polyphosphate multikinase

Reference/ChEBI CHEBI 17401
type: UnificationXref
id: CHEBI:17401
db: ChEBI

Reference/UniProt Q13572
type: UnificationXref
id: Q13572
db: UniProt

1D-Myo-inositol 1,4-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 1,4-bisphosphate

Reference/BioCyc MI-HEXAKISPHOSPHATE
type: UnificationXref
id: MI-HEXAKISPHOSPHATE
db: BioCyc

Compound/PW C001420 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reaction1352
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002676 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002677 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: 5-Diphosphoinositol pentakisphosphate
spontaneous: false
left: Bisdiphosphoinositol tetrakisphosphate
left: Water
name: Bisdiphosphoinositol tetrakisphosphate + Water → 5-Diphosphoinositol pentakisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Reaction1353
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002676 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002677 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Bisdiphosphoinositol tetrakisphosphate
spontaneous: false
left: Adenosine triphosphate
left: 5-Diphosphoinositol pentakisphosphate
name: 5-Diphosphoinositol pentakisphosphate + Adenosine triphosphate → Adenosine diphosphate + Bisdiphosphoinositol tetrakisphosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C001012 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Myo-inositol 4-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 52965
type: UnificationXref
id: CHEBI:52965
db: ChEBI

Reference/ChemSpider 17216032
type: UnificationXref
id: 17216032
db: ChemSpider

Reference/CAS 69256-53-7
type: UnificationXref
id: 69256-53-7
db: CAS

Reference/SMPDB SMP0000463
type: UnificationXref
id: SMP0000463
db: SMPDB

Reaction1356
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002676 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001908 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Myo-inositol hexakisphosphate
spontaneous: false
left: 5-Diphosphoinositol pentakisphosphate
left: Water
name: 5-Diphosphoinositol pentakisphosphate + Water ? Myo-inositol hexakisphosphate + Phosphate

Reference/SMPDB SMP0000462
type: UnificationXref
id: SMP0000462
db: SMPDB

2.7.4.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002676 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001908 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: 5-Diphosphoinositol pentakisphosphate
spontaneous: false
EC number: 2.7.4.21
left: Adenosine triphosphate
left: Myo-inositol hexakisphosphate
name: Adenosine triphosphate + Myo-inositol hexakisphosphate → 5-Diphosphoinositol pentakisphosphate + Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/ChEBI CHEBI 16322
type: UnificationXref
id: CHEBI:16322
db: ChEBI

Reaction349
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000923 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate
right: Adenosine diphosphate
spontaneous: false
left: Adenosine triphosphate
left: Inositol 1,3,4-trisphosphate
name: Adenosine triphosphate + Inositol 1,3,4-trisphosphate → 1D-Myo-inositol 1,3,4,6-tetrakisphosphate + Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C000892 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4-trisphosphate
stoichiometric coefficient: 1.0

Reference/BioCyc INOSITOL-1,4-BISPHOSPHATE
type: UnificationXref
id: INOSITOL-1,4-BISPHOSPHATE
db: BioCyc

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001155 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/2.0
participant stoichiometry: Compound/PW C002147 Nucleus/Stoichiometry/1.0
right: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.151
left: Inositol 1,4,5-trisphosphate
left: Adenosine triphosphate
name: 2 Adenosine triphosphate + Inositol 1,4,5-trisphosphate → 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + 2 Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/2.0
participant stoichiometry: Compound/PW C002147 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/2.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5,6-pentakisphosphate
spontaneous: false
EC number: 2.7.1.151
left: Adenosine triphosphate
left: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
name: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + 2 Adenosine triphosphate → 2 Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate
conversion direction: LEFT_TO_RIGHT

3.1.3.57
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001441 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001012 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000772 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: D-Myo-inositol 4-phosphate
right: Phosphoric acid
spontaneous: false
EC number: 3.1.3.57
left: 1D-Myo-inositol 1,4-bisphosphate
left: Water
name: 1D-Myo-inositol 1,4-bisphosphate + Water → D-Myo-inositol 4-phosphate + Phosphoric acid
conversion direction: LEFT_TO_RIGHT

3.1.3.57
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001441 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002679 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: 1D-Myo-inositol 3,4-bisphosphate
right: Phosphoric acid
spontaneous: false
EC number: 3.1.3.57
left: Inositol 1,3,4-trisphosphate
left: Water
name: Inositol 1,3,4-trisphosphate + Water → 1D-Myo-inositol 3,4-bisphosphate + Phosphoric acid
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C11555
type: UnificationXref
id: C11555
db: KEGG Compound

Reference/CAS 112791-61-4
type: UnificationXref
id: 112791-61-4
db: CAS