4-Hydroxyifosfamide → 4-Ketoifosfamide
Hydrogen Ion + Ifosfamide + NADPH + Oxygen → 4-Hydroxyifosfamide + NADP + Water
Ifosfamide + Oxygen + Water → 2-Dechloroethylifosfamide + 3-Dechloroethylifosfamide + Chloroacetaldehyde + Hydrogen peroxide
Aldehyde dehydrogenase, dimeric NADP-preferring
Aldoifosfamide (→) Transport: Homo sapiens, Liver, Cell, Cytoplasm to Homo sapiens, Cell, Cytoplasm
Aldoifosfamide + NAD + Water → Carboxyifosfamide + Hydrogen Ion + NADH
4-Hydroxyifosfamide → Aldoifosfamide
Acrolein + NAD + Water → Acrylic acid + Hydrogen Ion + NADH
Isophosphamide mustard → Chloride ion
Aldoifosfamide → Isophosphamide mustard
Isophosphamide mustard → Ifosforamide Aziridinium