Venlafaxine inhibits seratonin and noradrenaline transporters
Sodium-dependent noradrenaline transporter
NADH + Oxygen + Venlafaxine → Formaldehyde + N-Desmethylvenlafaxine + NAD + Water
O-Desmethylvenlafaxine → O-Desmethylvenlafaxine glucuronide
NADH + O-Desmethylvenlafaxine + Oxygen → Formaldehyde + N,O-Didesmethylvenlafaxine + NAD + Water
N,O-Didesmethylvenlafaxine → N,N,O-Tridesmethylvenlafaxine
NADH + Oxygen + Venlafaxine → Formaldehyde + NAD + O-Desmethylvenlafaxine + Water
N-Desmethylvenlafaxine + NADH + Oxygen → Formaldehyde + N,O-Didesmethylvenlafaxine + NAD + Water
N,O-Didesmethylvenlafaxine → N,O-Didesmethylvenlafaxine glucuronide
Venlafaxine (→) Transport: Homo sapiens, Blood Vessel, Cell, Extracellular Space to Homo sapiens, Brain, Extracellular Space