Sorafenib N-oxide → Sorafenib N-oxide glucuronide
Inhibition of UDP-glucuronosyltransferase 1-1
Sorafenib metabolite M4 → Sorafenib metabolite M5
Sorafenib N-oxide + Sorafenib metabolite M3 → Sorafenib metabolite M1
Sorafenib → Sorafenib metabolite M3
Sorafenib → Sorafenib metabolite M4
Sorafenib + Uridine diphosphate glucuronic acid → Sorafenib β-D-Glucuronide + Uridine 5'-diphosphate
Stromal cell-derived factor 2-like protein 1
Endoplasmic reticulum resident protein 29
Oxygen + Sorafenib + Water → Hydrogen peroxide + Sorafenib N-oxide