Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Compound/PW C001145 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Nicotinic acid
stoichiometric coefficient: 1.0

Reference/UniProt P27278
type: UnificationXref
id: P27278
db: UniProt

Reference/PubChem-compound 53481005
type: UnificationXref
id: 53481005
db: PubChem-compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Nicotinic acid
type: SmallMolecule
entity reference: Nicotinic acid

Adenosine monophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine monophosphate

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/KEGG Compound C03150
type: UnificationXref
id: C03150
db: KEGG Compound

Reference/ChemSpider 13554
type: UnificationXref
id: 13554
db: ChemSpider

Reference/TAXONOMY 83333
type: UnificationXref
id: 83333
db: TAXONOMY

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0011670
type: UnificationXref
id: HMDB0011670
db: HMDB

SubPathwayInteraction109719
type: Interaction
name: SubPathway109719Reaction
name: SubPathwayReaction
participant: NAD

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

Reference/ChemSpider 145043
type: UnificationXref
id: 145043
db: ChemSpider

D-ribofuranose 5-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 52742
chemical formula: C5H9O8P
molecular weight: 228.00461
structure: ChemicalStructure/PW C040975

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

NAD
type: SmallMolecule
entity reference: NAD

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C000143 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5961
type: UnificationXref
id: 5961
db: PubChem-compound

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Reference/ChEBI CHEBI 17111
type: UnificationXref
id: CHEBI:17111
db: ChEBI

β-nicotinamide D-ribonucleotide
type: SmallMolecule
cellular location: Cytosol
entity reference: β-nicotinamide D-ribonucleotide

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/PubChem-compound 165491
type: UnificationXref
id: 165491
db: PubChem-compound

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/ChEBI CHEBI 15940
type: UnificationXref
id: CHEBI:15940
db: ChEBI

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

NAD Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway109719
pathway component: SubPathwayInteraction109719
xref: Reference/PathWhiz PW000829
xref: Reference/SMPDB SMP0000849
name: SubPathway

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5746
type: UnificationXref
id: 5746
db: ChemSpider

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Transcriptional regulator nadR
type: ProteinReference
xref: Reference/UniProt P27278

8-Oxo-dGTP
type: SmallMoleculeReference
xref: Reference/PubChem-compound 53481005
xref: Reference/HMDB HMDB0011615
xref: Reference/CAS 139307-94-1
chemical formula: C10H16N5O14P3
molecular weight: 522.99066
structure: ChemicalStructure/PW C007204

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

ChemicalStructure/PW C001086
type: ChemicalStructure
structure format: SMILES
structure data: NC(=O)C1=CC=CN=C1

Reference/CAS 7540-64-9
type: UnificationXref
id: 7540-64-9
db: CAS

Nicotinate-nucleotide adenylyltransferase
type: Protein
entity reference: Nicotinate-nucleotide adenylyltransferase

Pyrazinamidase/nicotinamidase
type: Protein
entity reference: Pyrazinamidase/nicotinamidase

NAD Salvage
type: Pathway
pathway order: PathwayEnzymeReaction/5367
pathway order: PathwayEnzymeReaction/5368
pathway order: PathwayEnzymeReaction/5363
pathway order: PathwayEnzymeReaction/5374
pathway order: PathwayEnzymeReaction/5373
pathway order: PathwayEnzymeReaction/5365
pathway order: PathwayEnzymeReaction/5364
pathway order: PathwayEnzymeReaction/9085099
pathway order: PathwayEnzymeReaction/2122631
pathway order: PathwaySubPathway/109719
pathway order: PathwayEnzymeReaction/2122634
pathway order: PathwayEnzymeReaction/2122635
pathway order: PathwayEnzymeReaction/2122636
pathway component: NAD Biosynthesis
pathway component: 3.6.1.55
pathway component: Reaction3014
pathway component: ReactionCatalysis2985
pathway component: Reaction3013
pathway component: ReactionCatalysis2984
pathway component: Reaction3023
pathway component: ReactionCatalysis2034600
pathway component: 2.7.7.1
pathway component: 6.3.1.5
pathway component: Reaction3021
pathway component: ReactionCatalysis2978
pathway component: Reaction6079
pathway component: 2.7.7.18
pathway component: ReactionCatalysis2981
pathway component: ReactionCatalysis2980
pathway component: 3.5.1.42
pathway component: ReactionCatalysis2983
pathway component: 6.3.4.21
pathway component: 3.5.1.-
pathway component: ReactionCatalysis2982
xref: Reference/PathWhiz PW000830
xref: Reference/SMPDB SMP0000850
organism: Escherichia coli

Reference/PubChem-compound 53481020
type: UnificationXref
id: 53481020
db: PubChem-compound

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

Reference/ChEBI CHEBI 18304
type: UnificationXref
id: CHEBI:18304
db: ChEBI

Reference/PathWhiz PW000830
type: UnificationXref
id: PW000830
db: PathWhiz

Pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyrophosphate

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/HMDB HMDB0001406
type: UnificationXref
id: HMDB0001406
db: HMDB

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C000681
type: ChemicalStructure
structure format: SMILES

Reference/PathWhiz PW000829
type: UnificationXref
id: PW000829
db: PathWhiz

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Protein/6375 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: NH(3)-dependent NAD(+) synthetase
stoichiometric coefficient: 2.0

nicotinate β-D-ribonucleotide
type: SmallMolecule
entity reference: nicotinate β-D-ribonucleotide

Reference/PubChem-compound 938
type: UnificationXref
id: 938
db: PubChem-compound

β-nicotinamide D-ribonucleotide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 14181
xref: Reference/ChEBI CHEBI 14648
xref: Reference/ChemSpider 13554
xref: Reference/HMDB HMDB0059645
chemical formula: C11H16N2O8P
molecular weight: 335.06442
structure: ChemicalStructure/PW C040082

Reference/PubChem-compound 936
type: UnificationXref
id: 936
db: PubChem-compound

nicotinate β-D-ribonucleotide
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15763
xref: Reference/KEGG Compound C01185
xref: Reference/ChemSpider 108822
xref: Reference/HMDB HMDB0059646
xref: Reference/PubChem-compound 121992
chemical formula: C11H15NO9P
molecular weight: 336.04843
structure: ChemicalStructure/PW C040083

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

β-nicotinamide D-ribonucleotide
type: SmallMolecule
entity reference: β-nicotinamide D-ribonucleotide

Reference/KEGG Compound C00119
type: UnificationXref
id: C00119
db: KEGG Compound

Nicotinic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Nicotinic acid

Ammonium
type: SmallMolecule
entity reference: Ammonium

Reference/ChEBI CHEBI 15763
type: UnificationXref
id: CHEBI:15763
db: ChEBI

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

L-Glutamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000641
xref: Reference/ChEBI CHEBI 18050
xref: Reference/ChemSpider 5746
xref: Reference/BioCyc GLN
xref: Reference/KEGG Compound C00064
xref: Reference/PubChem-compound 5961
xref: Reference/CAS 56-85-9
chemical formula: C5H10N2O3
molecular weight: 146.06914
structure: ChemicalStructure/PW C000500

Compound/PW C040083/Stoichiometry/1.0
type: Stoichiometry
physical entity: nicotinate β-D-ribonucleotide
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0059646
type: UnificationXref
id: HMDB0059646
db: HMDB

Reference/HMDB HMDB0059645
type: UnificationXref
id: HMDB0059645
db: HMDB

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Compound/PW C000681/Stoichiometry/1.0
type: Stoichiometry
physical entity: Nicotinamide riboside
stoichiometric coefficient: 1.0

Compound/PW C000170 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

8-oxo-dGTP diphosphatase
type: ProteinReference
xref: Reference/UniProt P08337
organism: BiologicalState235

Reference/SMPDB SMP0000849
type: UnificationXref
id: SMP0000849
db: SMPDB

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Phosphoribosyl pyrophosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00119
xref: Reference/ChemSpider 7062
xref: Reference/CAS 7540-64-9
xref: Reference/HMDB HMDB0000280
xref: Reference/PubChem-compound 7339
xref: Reference/BioCyc PRPP
xref: Reference/ChEBI CHEBI 17111
chemical formula: C5H13O14P3
molecular weight: 389.9518
structure: ChemicalStructure/PW C000190

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Nicotinate phosphoribosyltransferase
type: ProteinReference
xref: Reference/UniProt P18133
organism: Escherichia coli

ReactionCatalysis2978
type: Catalysis
controller: NAD synthetase, NH3-dependent
controlled: 6.3.1.5
control type: ACTIVATION

ChemicalStructure/PW C007204
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Compound/PW C000915/Stoichiometry/1.0
type: Stoichiometry
physical entity: Nicotinic acid adenine dinucleotide
stoichiometric coefficient: 1.0

Compound/PW C000500 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Compound/PW C000721 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

BiologicalState235
type: BioSource
xref: Reference/TAXONOMY 83333
name: Escherichia coli (strain K12)

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Protein/6464/Stoichiometry/4.0
type: Stoichiometry
physical entity: Transcriptional regulator nadR
stoichiometric coefficient: 4.0

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChEBI CHEBI 17154
type: UnificationXref
id: CHEBI:17154
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

NH(3)-dependent NAD(+) synthetase
type: ProteinReference
xref: Reference/UniProt P18843
organism: Escherichia coli

Reference/UniProt P21369
type: UnificationXref
id: P21369
db: UniProt

ReactionCatalysis2985
type: Catalysis
controller: NadR DNA-binding transcriptional repressor and NMN adenylyltransferase
controlled: Reaction3023
control type: ACTIVATION

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis2984
type: Catalysis
controller: NadR DNA-binding transcriptional repressor and NMN adenylyltransferase
controlled: 2.7.7.1
control type: ACTIVATION

Compound/PW C040082/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-nicotinamide D-ribonucleotide
stoichiometric coefficient: 1.0

Reference/BioCyc GLN
type: UnificationXref
id: GLN
db: BioCyc

Reference/SMPDB SMP0000850
type: UnificationXref
id: SMP0000850
db: SMPDB

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

ReactionCatalysis2981
type: Catalysis
controller: Nicotinate phosphoribosyltransferase
controlled: 6.3.4.21
control type: ACTIVATION

ReactionCatalysis2980
type: Catalysis
controller: Pyrazinamidase/nicotinamidase
controlled: 3.5.1.-
control type: ACTIVATION

ReactionCatalysis2983
type: Catalysis
controller: Nicotinate-nucleotide adenylyltransferase
controlled: 2.7.7.18
control type: ACTIVATION

ReactionCatalysis2982
type: Catalysis
controller: NMN amidohydrolase
controlled: 3.5.1.42
control type: ACTIVATION

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/KEGG Compound C00253
type: UnificationXref
id: C00253
db: KEGG Compound

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

Reference/PubChem-compound 7339
type: UnificationXref
id: 7339
db: PubChem-compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/ChemSpider 913
type: UnificationXref
id: 913
db: ChemSpider

D-ribofuranose 5-phosphate
type: SmallMolecule
entity reference: D-ribofuranose 5-phosphate

Reference/ChemSpider 911
type: UnificationXref
id: 911
db: ChemSpider

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reaction3014
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040082/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040975/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001086/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Hydrogen Ion
right: Niacinamide
right: D-ribofuranose 5-phosphate
spontaneous: true
left: Water
left: β-nicotinamide D-ribonucleotide
name: Water + β-nicotinamide D-ribonucleotide → D-ribofuranose 5-phosphate + Hydrogen Ion + Niacinamide
conversion direction: LEFT_TO_RIGHT

Reaction3013
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040082 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000032 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/2.0
right: β-nicotinamide D-ribonucleotide
right: Adenosine monophosphate
right: Hydrogen Ion
spontaneous: true
left: NAD
left: Water
name: NAD + Water → Adenosine monophosphate + 2 Hydrogen Ion + β-nicotinamide D-ribonucleotide
conversion direction: LEFT_TO_RIGHT

Pyrazinamidase/nicotinamidase
type: ProteinReference
xref: Reference/UniProt P21369

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Nicotinate-nucleotide adenylyltransferase
type: ProteinReference
xref: Reference/UniProt P0A752

6.3.1.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000032 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000915 Cytosol/Stoichiometry/1.0
right: NAD
right: Adenosine monophosphate
right: Hydrogen Ion
right: Pyrophosphate
right: L-Glutamic acid
spontaneous: false
EC number: 6.3.1.5
left: L-Glutamine
left: Adenosine triphosphate
left: Nicotinic acid adenine dinucleotide
left: Water
name: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water → Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Nicotinic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15940
xref: Reference/HMDB HMDB0001488
xref: Reference/KEGG Compound C00253
xref: Reference/PubChem-compound 938
xref: Reference/CAS 59-67-6
xref: Reference/ChemSpider 913
xref: Reference/BioCyc NIACINE
chemical formula: C6H5NO2
molecular weight: 123.03203
structure: ChemicalStructure/PW C001145

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/ChEBI CHEBI 14648
type: UnificationXref
id: CHEBI:14648
db: ChEBI

8-Oxo-dGMP
type: SmallMolecule
cellular location: Cytoplasm
entity reference: 8-Oxo-dGMP

2.7.7.18
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040083/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000915/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Nicotinic acid adenine dinucleotide
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.18
left: Hydrogen Ion
left: nicotinate β-D-ribonucleotide
left: Adenosine triphosphate
name: Adenosine triphosphate + Hydrogen Ion + nicotinate β-D-ribonucleotide → Nicotinic acid adenine dinucleotide + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

3.5.1.42
type: BiochemicalReaction
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040082/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040083/Stoichiometry/1.0
right: Ammonium
right: nicotinate β-D-ribonucleotide
spontaneous: false
EC number: 3.5.1.42
left: Water
left: β-nicotinamide D-ribonucleotide
name: Water + β-nicotinamide D-ribonucleotide → Ammonium + nicotinate β-D-ribonucleotide
conversion direction: LEFT_TO_RIGHT

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

6.3.4.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000190 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040083 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001145 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Phosphate
right: nicotinate β-D-ribonucleotide
right: Adenosine diphosphate
right: Pyrophosphate
spontaneous: false
EC number: 6.3.4.21
left: Nicotinic acid
left: Adenosine triphosphate
left: Phosphoribosyl pyrophosphate
left: Water
name: Adenosine triphosphate + Nicotinic acid + Phosphoribosyl pyrophosphate + Water → Adenosine diphosphate + Phosphate + Pyrophosphate + nicotinate β-D-ribonucleotide
conversion direction: LEFT_TO_RIGHT

3.5.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001086/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001145/Stoichiometry/1.0
right: Nicotinic acid
right: Ammonium
spontaneous: false
EC number: 3.5.1.-
left: Water
left: Niacinamide
name: Niacinamide + Water → Ammonium + Nicotinic acid
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P0A6G3
type: UnificationXref
id: P0A6G3
db: UniProt

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Compound/PW C000190 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoribosyl pyrophosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000915
type: ChemicalStructure
structure format: SMILES

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

L-Glutamic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Glutamic acid

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

nicotinate β-D-ribonucleotide
type: SmallMolecule
cellular location: Cytosol
entity reference: nicotinate β-D-ribonucleotide

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Reference/PubChem-compound 14181
type: UnificationXref
id: 14181
db: PubChem-compound

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

8-Oxo-dGMP
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0011670
xref: Reference/PubChem-compound 53481020
chemical formula: C10H14N5O8P
molecular weight: 363.058
structure: ChemicalStructure/PW C007250

Reaction6079
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: NAD
spontaneous: false
left: NADP
left: Water
name: NADP + Water → NAD + Phosphate
conversion direction: LEFT_TO_RIGHT

NADP
type: SmallMolecule
cellular location: Cytosol
entity reference: NADP

Compound/PW C001145/Stoichiometry/1.0
type: Stoichiometry
physical entity: Nicotinic acid
stoichiometric coefficient: 1.0

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00153
type: UnificationXref
id: C00153
db: KEGG Compound

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Compound/PW C040034 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 2.0

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Niacinamide
type: SmallMoleculeReference
xref: Reference/CAS 98-92-0
xref: Reference/HMDB HMDB0001406
xref: Reference/KEGG Compound C00153
xref: Reference/PubChem-compound 936
xref: Reference/BioCyc NIACINAMIDE
xref: Reference/ChemSpider 911
xref: Reference/ChEBI CHEBI 17154
chemical formula: C6H6N2O
molecular weight: 122.04801
structure: ChemicalStructure/PW C001086

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Water
type: SmallMolecule
entity reference: Water

Reference/ChEBI CHEBI 52742
type: UnificationXref
id: CHEBI:52742
db: ChEBI

Reference/ChemSpider 108822
type: UnificationXref
id: 108822
db: ChemSpider

ChemicalStructure/PW C001145
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C1=CN=CC=C1

Nicotinate phosphoribosyltransferase
type: Protein
cellular location: Cytosol
entity reference: Nicotinate phosphoribosyltransferase

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Compound/PW C040082 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-nicotinamide D-ribonucleotide
stoichiometric coefficient: 1.0

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/CAS 56-85-9
type: UnificationXref
id: 56-85-9
db: CAS

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reaction3023
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040082/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Pyrophosphate
spontaneous: false
left: Hydrogen Ion
left: β-nicotinamide D-ribonucleotide
left: Adenosine triphosphate
name: Adenosine triphosphate + Hydrogen Ion + β-nicotinamide D-ribonucleotide → NAD + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 7062
type: UnificationXref
id: 7062
db: ChemSpider

ReactionCatalysis2034600
type: Catalysis
controller: 8-oxo-dGTP diphosphatase
controlled: 3.6.1.55
control type: ACTIVATION

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

2.7.7.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040082/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000681/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: β-nicotinamide D-ribonucleotide
spontaneous: false
EC number: 2.7.7.1
left: Nicotinamide riboside
left: Adenosine triphosphate
name: Adenosine triphosphate + Nicotinamide riboside → Adenosine diphosphate + Hydrogen Ion + β-nicotinamide D-ribonucleotide
conversion direction: LEFT_TO_RIGHT

Reaction3021
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040082 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000681 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Nicotinamide riboside
spontaneous: false
left: β-nicotinamide D-ribonucleotide
left: Water
name: Water + β-nicotinamide D-ribonucleotide → Nicotinamide riboside + Phosphate
conversion direction: LEFT_TO_RIGHT

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Reference/UniProt P18843
type: UnificationXref
id: P18843
db: UniProt

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

NMN amidohydrolase
type: Protein
entity reference: NMN amidohydrolase

Nicotinamide riboside
type: SmallMolecule
entity reference: Nicotinamide riboside

ChemicalStructure/PW C040083
type: ChemicalStructure
structure format: SMILES

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

ChemicalStructure/PW C040082
type: ChemicalStructure
structure format: SMILES

Compound/PW C000032 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

Nicotinamide riboside
type: SmallMoleculeReference
xref: Reference/ChemSpider 388956
xref: Reference/BioCyc NICOTINAMIDE RIBOSE
xref: Reference/HMDB HMDB0000855
xref: Reference/KEGG Compound C03150
xref: Reference/PubChem-compound 439924
xref: Reference/CAS 1341-23-7
xref: Reference/ChEBI CHEBI 15927
chemical formula: C11H15N2O5
molecular weight: 255.0981
structure: ChemicalStructure/PW C000681

ChemicalStructure/PW C007250
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/KEGG Compound C00857
type: UnificationXref
id: C00857
db: KEGG Compound

3.6.1.55
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007204 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007250 Cytoplasm/Stoichiometry/1.0
right: 8-Oxo-dGMP
right: Pyrophosphate
spontaneous: false
EC number: 3.6.1.55
left: Water
left: 8-Oxo-dGTP
name: 8-Oxo-dGTP + Water ↔ 8-Oxo-dGMP + Pyrophosphate
conversion direction: REVERSIBLE

Reference/PubChem-compound 121992
type: UnificationXref
id: 121992
db: PubChem-compound

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/BioCyc NIACINAMIDE
type: UnificationXref
id: NIACINAMIDE
db: BioCyc

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001488
type: UnificationXref
id: HMDB0001488
db: HMDB

Reference/BioCyc NICOTINAMIDE RIBOSE
type: UnificationXref
id: NICOTINAMIDE_RIBOSE
db: BioCyc

Niacinamide
type: SmallMolecule
entity reference: Niacinamide

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

NAD
type: SmallMolecule
cellular location: Cytosol
entity reference: NAD

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C040975/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-ribofuranose 5-phosphate
stoichiometric coefficient: 1.0

Compound/PW C000095 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/CAS 59-67-6
type: UnificationXref
id: 59-67-6
db: CAS

Reference/KEGG Compound C00064
type: UnificationXref
id: C00064
db: KEGG Compound

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Compound/PW C000915 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Nicotinic acid adenine dinucleotide
stoichiometric coefficient: 1.0

Pyrophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyrophosphate

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Reference/UniProt P0A752
type: UnificationXref
id: P0A752
db: UniProt

Reference/HMDB HMDB0000280
type: UnificationXref
id: HMDB0000280
db: HMDB

Nicotinic acid adenine dinucleotide
type: SmallMolecule
cellular location: Cytosol
entity reference: Nicotinic acid adenine dinucleotide

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Compound/PW C007204 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: 8-Oxo-dGTP
stoichiometric coefficient: 1.0

Reference/ChemSpider 388956
type: UnificationXref
id: 388956
db: ChemSpider

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/CAS 139307-94-1
type: UnificationXref
id: 139307-94-1
db: CAS

Nicotinamide riboside
type: SmallMolecule
cellular location: Cytosol
entity reference: Nicotinamide riboside

Compound/PW C007250 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: 8-Oxo-dGMP
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/CAS 6450-77-7
type: UnificationXref
id: 6450-77-7
db: CAS

Compound/PW C040083 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: nicotinate β-D-ribonucleotide
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000855
type: UnificationXref
id: HMDB0000855
db: HMDB

Reference/HMDB HMDB0011615
type: UnificationXref
id: HMDB0011615
db: HMDB

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/CAS 1341-23-7
type: UnificationXref
id: 1341-23-7
db: CAS

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

NH(3)-dependent NAD(+) synthetase
type: Protein
cellular location: Cytosol
entity reference: NH(3)-dependent NAD(+) synthetase

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Compound/PW C001086/Stoichiometry/1.0
type: Stoichiometry
physical entity: Niacinamide
stoichiometric coefficient: 1.0

8-oxo-dGTP diphosphatase
type: Protein
cellular location: Cytoplasm
entity reference: 8-oxo-dGTP diphosphatase

Nicotinic acid adenine dinucleotide
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001179
xref: Reference/ChEBI CHEBI 18304
xref: Reference/CAS 6450-77-7
xref: Reference/ChemSpider 145043
xref: Reference/BioCyc DEAMIDO-NAD
xref: Reference/KEGG Compound C00857
xref: Reference/PubChem-compound 165491
chemical formula: C21H27N6O15P2
molecular weight: 665.10095
structure: ChemicalStructure/PW C000915

Transcriptional regulator nadR
type: Protein
entity reference: Transcriptional regulator nadR

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Compound/PW C022608/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/KEGG Compound C01185
type: UnificationXref
id: C01185
db: KEGG Compound

Phosphoribosyl pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphoribosyl pyrophosphate

Reference/ChEBI CHEBI 15927
type: UnificationXref
id: CHEBI:15927
db: ChEBI

NAD synthetase, NH3-dependent
type: Complex
component stoichiometry: Protein/6375 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: NH(3)-dependent NAD(+) synthetase

Nicotinic acid adenine dinucleotide
type: SmallMolecule
entity reference: Nicotinic acid adenine dinucleotide

Reference/UniProt P08337
type: UnificationXref
id: P08337
db: UniProt

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

L-Glutamine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Glutamine

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

ChemicalStructure/PW C000500
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(N)=O)C(O)=O

NMN amidohydrolase
type: ProteinReference
xref: Reference/UniProt P0A6G3

Reference/BioCyc PRPP
type: UnificationXref
id: PRPP
db: BioCyc

Reference/UniProt P18133
type: UnificationXref
id: P18133
db: UniProt

Reference/ChEBI CHEBI 18050
type: UnificationXref
id: CHEBI:18050
db: ChEBI

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C000190
type: ChemicalStructure
structure format: SMILES

NadR DNA-binding transcriptional repressor and NMN adenylyltransferase
type: Complex
component stoichiometry: Protein/6464/Stoichiometry/4.0
component: Transcriptional regulator nadR

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

8-Oxo-dGTP
type: SmallMolecule
cellular location: Cytoplasm
entity reference: 8-Oxo-dGTP

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

ChemicalStructure/PW C040975
type: ChemicalStructure
structure format: SMILES
structure data: OC1OC(COP([O-])([O-])=O)C(O)C1O

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc NIACINE
type: UnificationXref
id: NIACINE
db: BioCyc

Reference/HMDB HMDB0001179
type: UnificationXref
id: HMDB0001179
db: HMDB

Reference/HMDB HMDB0000641
type: UnificationXref
id: HMDB0000641
db: HMDB

Reference/BioCyc DEAMIDO-NAD
type: UnificationXref
id: DEAMIDO-NAD
db: BioCyc

Reference/CAS 98-92-0
type: UnificationXref
id: 98-92-0
db: CAS

Compound/PW C000681 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Nicotinamide riboside
stoichiometric coefficient: 1.0

Reference/PubChem-compound 439924
type: UnificationXref
id: 439924
db: PubChem-compound

NAD
type: SmallMolecule
cellular location: Cytoplasm
entity reference: NAD
name: SubPathwayOutput