Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Compound/PW C000504/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

Phosphocarrier protein HPr
type: Protein
cellular location: Inner Membrane
entity reference: Phosphocarrier protein HPr

ReactionCoupledTransportCatalysis178
type: Catalysis
controller: mannose PTS permease
controlled: ReactionCoupledTransport144
control type: ACTIVATION

Glycogen phosphorylase
type: ProteinReference
xref: Reference/UniProt P0AC86

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

[PTS enzyme I]-Nπ-phospho-L-histidine
type: ProteinReference
organism: Escherichia coli

Galactose-1-phosphate uridylyltransferase
type: Protein
entity reference: Galactose-1-phosphate uridylyltransferase

[PTS enzyme I]-L-histidine
type: ProteinReference
organism: Escherichia coli

Reference/ChemSpider 109086
type: UnificationXref
id: 109086
db: ChemSpider

Reference/PubChem-compound 16500
type: UnificationXref
id: 16500
db: PubChem-compound

Compound/PW C001104 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

ReactionCoupledTransportCatalysis172
type: Catalysis
controller: glucose PTS permease
controlled: 2.7.1.69
control type: ACTIVATION

Maltotriose
type: SmallMolecule
entity reference: Maltotriose

Maltose/maltodextrin import ATP-binding protein MalK
type: ProteinReference
xref: Reference/UniProt P68187
organism: Escherichia coli

BiologicalState304
type: BioSource
xref: Reference/TAXONOMY 2
name: Bacteria

Glucose-specific phosphotransferase enzyme IIA component
type: ProteinReference
xref: Reference/UniProt P69783
organism: Escherichia coli

Reference/UniProt P19642
type: UnificationXref
id: P19642
db: UniProt

Compound/PW C041033/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-glucose-1-phosphate
stoichiometric coefficient: 1.0

Reference/UniProt P23917
type: UnificationXref
id: P23917
db: UniProt

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/ChemSpider 58238
type: UnificationXref
id: 58238
db: ChemSpider

ChemicalStructure/PW C042898
type: ChemicalStructure
structure format: SMILES
structure data: O[C@H]1O[C@H](OP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

Reference/KEGG Compound C00689
type: UnificationXref
id: C00689
db: KEGG Compound

ChemicalStructure/PW C042658
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00446
type: UnificationXref
id: C00446
db: KEGG Compound

Glycogen
type: SmallMolecule
entity reference: Glycogen

Reference/UniProt P0AEX9
type: UnificationXref
id: P0AEX9
db: UniProt

Reference/KEGG Compound C00688
type: UnificationXref
id: C00688
db: KEGG Compound

Compound/PW C001906/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

α-D-glucose-1-phosphate
type: SmallMolecule
entity reference: α-D-glucose-1-phosphate

Starch and Sucrose Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/7076
pathway order: PathwayEnzymeReaction/7074
pathway order: PathwayEnzymeReaction/7096
pathway order: PathwayEnzymeReaction/7075
pathway order: PathwayEnzymeReaction/7094
pathway order: PathwayEnzymeReaction/7073
pathway order: PathwayEnzymeReaction/7095
pathway order: PathwayEnzymeReaction/7092
pathway order: PathwayEnzymeReaction/22395
pathway order: PathwayEnzymeReaction/7093
pathway order: PathwayEnzymeReaction/7059
pathway order: PathwayEnzymeReaction/7078
pathway order: PathwaySubPathway/109866
pathway order: PathwayEnzymeReaction/2123104
pathway order: PathwayEnzymeReaction/7090
pathway order: PathwayEnzymeReaction/2123105
pathway order: PathwayEnzymeReaction/2122833
pathway order: PathwayEnzymeReaction/2122834
pathway order: PathwayEnzymeReaction/2122835
pathway order: PathwayEnzymeReaction/2122836
pathway order: PathwayEnzymeReaction/2122837
pathway order: PathwayTransport/7063
pathway order: PathwayEnzymeReaction/7087
pathway order: PathwayEnzymeReaction/2122838
pathway order: PathwayEnzymeReaction/7088
pathway order: PathwayEnzymeReaction/2122839
pathway order: PathwayEnzymeReaction/7064
pathway order: PathwayTransport/7060
pathway order: PathwayEnzymeReaction/7084
pathway order: PathwayEnzymeReaction/7082
pathway order: PathwayEnzymeReaction/22407
pathway order: PathwayTransport/7067
pathway order: PathwayEnzymeReaction/7069
pathway order: PathwayEnzymeReaction/7089
pathway order: PathwayEnzymeReaction/22403
pathway order: PathwayEnzymeReaction/2122840
pathway order: PathwayEnzymeReaction/2122841
pathway order: PathwayEnzymeReaction/7080
pathway order: PathwayEnzymeReaction/2122842
pathway order: PathwayEnzymeReaction/2122843
pathway order: PathwayEnzymeReaction/2122846
pathway component: Reaction3519
pathway component: ReactionCoupledTransportCatalysis178
pathway component: ReactionCoupledTransportCatalysis172
pathway component: ReactionCatalysis3503
pathway component: Reaction3354
pathway component: ReactionCatalysis3504
pathway component: ReactionCatalysis5967
pathway component: ReactionCatalysis3501
pathway component: ReactionCatalysis5966
pathway component: ReactionCatalysis3502
pathway component: 5.4.2.6
pathway component: 5.3.1.9
pathway component: ReactionCatalysis3505
pathway component: ReactionCoupledTransport156
pathway component: 3.2.1.28
pathway component: 3.2.1.-
pathway component: 3.6.3.19
pathway component: ReactionCoupledTransport155
pathway component: 3.1.3.12
pathway component: Transport433
pathway component: ReactionCoupledTransport152
pathway component: 2.4.1.15
pathway component: Transport432
pathway component: 2.4.1.21
pathway component: 2.7.1.69
pathway component: ReactionCatalysis3500
pathway component: 2.7.7.27
pathway component: ReactionCatalysis5962
pathway component: Transport434
pathway component: Reaction3510
pathway component: Reaction3509
pathway component: ReactionCoupledTransportCatalysis189
pathway component: 4.2.1.46
pathway component: 2.4.1.1
pathway component: ReactionCoupledTransportCatalysis188
pathway component: ReactionCoupledTransportCatalysis187
pathway component: ReactionCoupledTransportCatalysis186

ReactionCoupledTransportCatalysis189
type: Catalysis
controller: maltose ABC transporter
controlled: ReactionCoupledTransport155
control type: ACTIVATION

Reference/KEGG Compound C00208
type: UnificationXref
id: C00208
db: KEGG Compound

ReactionCoupledTransportCatalysis188
type: Catalysis
controller: maltose ABC transporter
controlled: 3.6.3.19
control type: ACTIVATION

Compound/PW C002734 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-β-L-rhamnose
stoichiometric coefficient: 1.0

ReactionCoupledTransportCatalysis187
type: Catalysis
controller: trehalose PTS permease
controlled: 2.7.1.69
control type: ACTIVATION

ReactionCoupledTransportCatalysis186
type: Catalysis
controller: glucose PTS permease
controlled: ReactionCoupledTransport152
control type: ACTIVATION

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

PTS system mannose-specific EIIAB component
type: ProteinReference
xref: Reference/UniProt P69797
organism: Escherichia coli

Glycogen debranching enzyme
type: ProteinReference
xref: Reference/UniProt P15067

Reference/CAS 53188-23-1
type: UnificationXref
id: 53188-23-1
db: CAS

Periplasmic trehalase
type: ProteinReference
xref: Reference/UniProt P13482
organism: BiologicalState304

Reaction179452
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000077 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000077/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Cytosol/Stoichiometry/1.0
right: D-Glucose
spontaneous: false
left: α-D-Glucose
name: α-D-Glucose → D-Glucose
conversion direction: LEFT_TO_RIGHT

PTS system glucose-specific EIICB component
type: ProteinReference
xref: Reference/UniProt P69786
organism: Escherichia coli

Reference/PubChem-compound 53477771
type: UnificationXref
id: 53477771
db: PubChem-compound

Compound/PW C000177/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sucrose
stoichiometric coefficient: 1.0

Protein/6683 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Maltose/maltodextrin import ATP-binding protein MalK
stoichiometric coefficient: 2.0

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Water
type: SmallMolecule
cellular location: Outer Membrane
entity reference: Water

Reference/ChEBI CHEBI 42560
type: UnificationXref
id: CHEBI:42560
db: ChEBI

Reference/HMDB HMDB0003498
type: UnificationXref
id: HMDB0003498
db: HMDB

α-D-glucose-1-phosphate
type: SmallMoleculeReference
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C041033

Reference/KEGG Compound C00459
type: UnificationXref
id: C00459
db: KEGG Compound

Reference/UniProt P0AA04
type: UnificationXref
id: P0AA04
db: UniProt

Reference/ChemSpider 388455
type: UnificationXref
id: 388455
db: ChemSpider

ChemicalStructure/PW C042663
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P31678
type: UnificationXref
id: P31678
db: UniProt

Reference/ChemSpider 5743
type: UnificationXref
id: 5743
db: ChemSpider

Reference/UniProt P31677
type: UnificationXref
id: P31677
db: UniProt

SubPathwayInteraction109866
type: Interaction
name: SubPathway109866Reaction
name: SubPathwayReaction
participant: β-D-Glucose 6-phosphate

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

4-alpha-glucanotransferase
type: ProteinReference
xref: Reference/UniProt P15977

Reference/CAS 365-08-2
type: UnificationXref
id: 365-08-2
db: CAS

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Compound/PW C042934 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: α,α-trehalose
stoichiometric coefficient: 1.0

dTDP-4-dehydrorhamnose 3,5-epimerase
type: ProteinReference
xref: Reference/UniProt P37745

Compound/PW C042934/Stoichiometry/1.0
type: Stoichiometry
physical entity: α,α-trehalose
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

ReactionCoupledTransportCatalysis190
type: Catalysis
controller: maltose ABC transporter
controlled: ReactionCoupledTransport156
control type: ACTIVATION

Reference/CAS 2280-44-6
type: UnificationXref
id: 2280-44-6
db: CAS

Reference/UniProt P15067
type: UnificationXref
id: P15067
db: UniProt

dTDP-glucose 4,6-dehydratase 2
type: ProteinReference
xref: Reference/UniProt P27830

2.7.7.24
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001035/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041033/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001024/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: dTDP-D-glucose
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.24
left: Thymidine 5'-triphosphate
left: α-D-glucose-1-phosphate
left: Hydrogen Ion
name: Hydrogen Ion + Thymidine 5'-triphosphate + α-D-glucose-1-phosphate → Pyrophosphate + dTDP-D-glucose
conversion direction: LEFT_TO_RIGHT

dTDP-4-dehydrorhamnose reductase
type: ProteinReference
xref: Reference/UniProt P37760
organism: BiologicalState304

Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
type: UnificationXref
id: ALPHA-GLUCOSE-16-BISPHOSPHATE
db: BioCyc

Reference/PubChem-compound 439177
type: UnificationXref
id: 439177
db: PubChem-compound

Reference/ChemSpider 9166684
type: UnificationXref
id: 9166684
db: ChemSpider

Reference/PubChem-compound 64968
type: UnificationXref
id: 64968
db: PubChem-compound

ChemicalStructure/PW C001083
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 28102
type: UnificationXref
id: CHEBI:28102
db: ChEBI

Reference/UniProt P21517
type: UnificationXref
id: P21517
db: UniProt

Trehalose-phosphate phosphatase
type: Protein
cellular location: Cytosol
entity reference: Trehalose-phosphate phosphatase

Reference/BioCyc CPD0-971
type: UnificationXref
id: CPD0-971
db: BioCyc

β-D-Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 388538
xref: Reference/KEGG Compound C01172
xref: Reference/ChEBI CHEBI 17719
xref: Reference/HMDB HMDB0003498
xref: Reference/PubChem-compound 439427
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001906

Maltose-binding periplasmic protein
type: Protein
cellular location: Inner Membrane
entity reference: Maltose-binding periplasmic protein

[PTS enzyme I]-L-histidine
type: Protein
cellular location: Inner Membrane
entity reference: [PTS enzyme I]-L-histidine

Reference/PubChem-compound 53477679
type: UnificationXref
id: 53477679
db: PubChem-compound

Reference/PubChem-compound 6031
type: UnificationXref
id: 6031
db: PubChem-compound

Reference/CAS 133-89-1
type: UnificationXref
id: 133-89-1
db: CAS

Reference/KEGG Compound C00221
type: UnificationXref
id: C00221
db: KEGG Compound

Reference/ChemSpider 58493
type: UnificationXref
id: 58493
db: ChemSpider

Compound/PW C001083 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Protein/Generic213 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: [PTS enzyme I]-Nπ-phospho-L-histidine
stoichiometric coefficient: 1.0

Maltose-binding periplasmic protein
type: ProteinReference
xref: Reference/UniProt P0AEX9
organism: Escherichia coli

Reference/PubChem-compound 122336
type: UnificationXref
id: 122336
db: PubChem-compound

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine 5'-diphosphate

Reference/CAS 4484-88-2
type: UnificationXref
id: 4484-88-2
db: CAS

ChemicalStructure/PW C041111
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O

UDP-galactose
type: SmallMoleculeReference
chemical formula: C15H22N2Na2O17P2
molecular weight: 610.0189
structure: ChemicalStructure/PW C042663

Galactose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 110443
xref: Reference/KEGG Compound C00446
xref: Reference/ChEBI CHEBI 17973
xref: Reference/PubChem-compound 123912
xref: Reference/CAS 2255-14-3
xref: Reference/HMDB HMDB0000645
xref: Reference/BioCyc GALACTOSE-1P
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000504

ADP-glucose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15751
xref: Reference/HMDB HMDB0006557
xref: Reference/CAS 2140-58-1
xref: Reference/PubChem-compound 16500
xref: Reference/BioCyc ADP-D-GLUCOSE
xref: Reference/ChemSpider 15642
xref: Reference/KEGG Compound C00498
chemical formula: C16H25N5O15P2
molecular weight: 589.0822
structure: ChemicalStructure/PW C002809

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Compound/PW C000146 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChemSpider 5768
type: UnificationXref
id: 5768
db: ChemSpider

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

dTDP-glucose pyrophosphorylase
type: Complex
component stoichiometry: Protein/10364/Stoichiometry/4.0
component: Glucose-1-phosphate thymidylyltransferase 2

β-D-fructofuranose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: β-D-fructofuranose

glucose PTS permease
type: Complex
component stoichiometry: Protein/6694 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: PTS system glucose-specific EIICB component
component: Glucose-specific phosphotransferase enzyme IIA component

Reference/UniProt P0A6V1
type: UnificationXref
id: P0A6V1
db: UniProt

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reaction3354
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042663/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000504/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041033/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000193/Stoichiometry/1.0
right: Uridine diphosphate glucose
right: Galactose 1-phosphate
spontaneous: false
left: α-D-glucose-1-phosphate
left: UDP-galactose
name: UDP-galactose + α-D-glucose-1-phosphate → Galactose 1-phosphate + Uridine diphosphate glucose
conversion direction: LEFT_TO_RIGHT

Glucose-6-phosphate isomerase
type: ProteinReference
xref: Reference/UniProt P0A6T1
organism: BiologicalState304

Phosphoglucomutase-1
type: Protein
entity reference: Phosphoglucomutase-1

Trehalose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Trehalose 6-phosphate

5.4.2.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001906 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042898 Cytosol/Stoichiometry/1.0
right: β-D-glucose 1-phosphate
spontaneous: false
EC number: 5.4.2.6
left: β-D-Glucose 6-phosphate
name: β-D-Glucose 6-phosphate → β-D-glucose 1-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0006557
type: UnificationXref
id: HMDB0006557
db: HMDB

Putative sucrose phosphorylase
type: Protein
entity reference: Putative sucrose phosphorylase

5.3.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001906 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941 Cytosol/Stoichiometry/1.0
right: β-D-Glucose 6-phosphate
spontaneous: false
EC number: 5.3.1.9
left: β-D-fructofuranose 6-phosphate
name: β-D-fructofuranose 6-phosphate → β-D-Glucose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P0A6U8
type: UnificationXref
id: P0A6U8
db: UniProt

Compound/PW C041111 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose
stoichiometric coefficient: 1.0

Protein/7147 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Mannose permease IID component
stoichiometric coefficient: 2.0

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

D-Fructose
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-535
xref: Reference/ChEBI CHEBI 28645
xref: Reference/ChemSpider 388775
xref: Reference/PubChem-compound 439709
xref: Reference/KEGG Compound C02336
xref: Reference/HMDB HMDB0000660
xref: Reference/CAS 53188-23-1
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000517

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Compound/PW C000107/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Maltose
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001906
type: ChemicalStructure
structure format: SMILES

Trehalose 6-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001124
xref: Reference/KEGG Compound C00689
xref: Reference/BioCyc TREHALOSE-6P
xref: Reference/PubChem-compound 122336
xref: Reference/ChEBI CHEBI 18283
xref: Reference/CAS 4484-88-2
xref: Reference/ChemSpider 109086
chemical formula: C12H23O14P
molecular weight: 422.08255
structure: ChemicalStructure/PW C000878

Compound/PW C042658/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-4-dehydro-6-deoxy-D-glucose
stoichiometric coefficient: 1.0

Compound/PW C000077 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glucose
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

dTDP-4-dehydro-β-L-rhamnose
type: SmallMolecule
cellular location: Cytosol
entity reference: dTDP-4-dehydro-β-L-rhamnose

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/PubChem-compound 7427
type: UnificationXref
id: 7427
db: PubChem-compound

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Glucokinase
type: ProteinReference
xref: Reference/UniProt P0A6V8

Reference/HMDB HMDB0060081
type: UnificationXref
id: HMDB0060081
db: HMDB

α-D-Glucose
type: SmallMolecule
entity reference: α-D-Glucose

Compound/PW C000177 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sucrose
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Compound/PW C040941 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose 6-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 388322
type: UnificationXref
id: 388322
db: ChemSpider

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Glycogen synthase
type: ProteinReference
xref: Reference/UniProt P0A6U8

NADPH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADPH

Phosphocarrier protein HPr
type: ProteinReference
xref: Reference/UniProt P0AA04
organism: Escherichia coli

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Protein/10002/Stoichiometry/4.0
type: Stoichiometry
physical entity: Glucose-1-phosphate adenylyltransferase
stoichiometric coefficient: 4.0

PTS system maltose- and glucose-specific EIICB component
type: ProteinReference
xref: Reference/UniProt P19642

Reference/UniProt P0A6V8
type: UnificationXref
id: P0A6V8
db: UniProt

α-D-Glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003345
xref: Reference/ChemSpider 71358
xref: Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
xref: Reference/PubChem-compound 79025
xref: Reference/ChEBI CHEBI 17925
xref: Reference/CAS 492-62-6
xref: Reference/KEGG Compound C00267
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C001851

Compound/PW C000201 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

β-D-glucose 1-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: β-D-glucose 1-phosphate

β-D-fructofuranose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 42560
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C041111

Glycogen
type: SmallMoleculeReference
xref: Reference/BioCyc CPD0-971
xref: Reference/KEGG Compound C00182
xref: Reference/PubChem-compound 439177
xref: Reference/HMDB HMDB0000757
xref: Reference/CAS 9005-79-2
xref: Reference/ChEBI CHEBI 28087
xref: Reference/ChemSpider 388322
chemical formula: C24H42O21
molecular weight: 666.22186
structure: ChemicalStructure/PW C000605

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway109866
pathway component: SubPathwayInteraction109866
xref: Reference/PathWhiz PW000785
xref: Reference/SMPDB SMP0000807
name: SubPathway

Reference/ChemSpider 388775
type: UnificationXref
id: 388775
db: ChemSpider

D-Fructose
type: SmallMolecule
entity reference: D-Fructose

Reference/ChemSpider 388538
type: UnificationXref
id: 388538
db: ChemSpider

Reference/KEGG Compound C00015
type: UnificationXref
id: C00015
db: KEGG Compound

Reference/KEGG Compound C00498
type: UnificationXref
id: C00498
db: KEGG Compound

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

2.7.1.69
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000395 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001906 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/7464 Inner Membrane/Stoichiometry/1.0
right: Phosphocarrier protein HPr
right: β-D-Glucose 6-phosphate
spontaneous: false
EC number: 2.7.1.69
left: β-D-Glucose
left: Phosphocarrier protein HPr
name: HPr - phosphorylated + β-D-Glucose → HPr + β-D-Glucose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Compound/PW C044520 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-4-dehydro-β-L-rhamnose
stoichiometric coefficient: 1.0

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

dTDP-β-L-rhamnose
type: SmallMolecule
cellular location: Cytosol
entity reference: dTDP-β-L-rhamnose

ADP-glucose
type: SmallMolecule
entity reference: ADP-glucose

Maltotriose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Maltotriose

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/KEGG Compound C00029
type: UnificationXref
id: C00029
db: KEGG Compound

Reference/PubChem-compound 62698
type: UnificationXref
id: 62698
db: PubChem-compound

Maltotriose
type: SmallMoleculeReference
xref: Reference/KEGG Compound C01835
xref: Reference/PubChem-compound 439586
xref: Reference/CAS 1109-28-0
xref: Reference/ChEBI CHEBI 27931
xref: Reference/ChemSpider 388669
xref: Reference/HMDB HMDB0001262
xref: Reference/BioCyc MALTOTRIOSE
chemical formula: C18H32O16
molecular weight: 504.16904
structure: ChemicalStructure/PW C000975

Compound/PW C001035/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymidine 5'-triphosphate
stoichiometric coefficient: 1.0

dTDP-4-dehydro-β-L-rhamnose
type: SmallMolecule
entity reference: dTDP-4-dehydro-β-L-rhamnose

Reference/ChemSpider 388669
type: UnificationXref
id: 388669
db: ChemSpider

Reference/CAS 34612-38-9
type: UnificationXref
id: 34612-38-9
db: CAS

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Maltose transport system permease protein malF
type: ProteinReference
xref: Reference/UniProt P02916
organism: Escherichia coli

Galactose 1-phosphate
type: SmallMolecule
entity reference: Galactose 1-phosphate

Reference/KEGG Compound C00267
type: UnificationXref
id: C00267
db: KEGG Compound

Maltodextrin glucosidase
type: ProteinReference
xref: Reference/UniProt P21517
organism: BiologicalState304

Compound/PW C002975/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dextrin
stoichiometric coefficient: 1.0

Compound/PW C000395 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose
stoichiometric coefficient: 1.0

Compound/PW C000193/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucose
stoichiometric coefficient: 1.0

NADP
type: SmallMolecule
cellular location: Cytosol
entity reference: NADP

Reference/ChemSpider 15642
type: UnificationXref
id: 15642
db: ChemSpider

dTDP-4-dehydro-β-L-rhamnose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 45868
xref: Reference/KEGG Compound C00688
chemical formula: C16H24N2O15P2
molecular weight: 546.0652
structure: ChemicalStructure/PW C044520

Reference/BioCyc TTP
type: UnificationXref
id: TTP
db: BioCyc

Reference/ChemSpider 388998
type: UnificationXref
id: 388998
db: ChemSpider

Protein/6555 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: PTS system trehalose-specific EIIBC component
stoichiometric coefficient: 2.0

β-D-fructofuranose 6-phosphate
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: β-D-fructofuranose 6-phosphate

Reference/KEGG Compound C02336
type: UnificationXref
id: C02336
db: KEGG Compound

Reference/KEGG Compound C00031
type: UnificationXref
id: C00031
db: KEGG Compound

Reference/SMPDB SMP0000807
type: UnificationXref
id: SMP0000807
db: SMPDB

Maltose transport system permease protein malG
type: ProteinReference
xref: Reference/UniProt P68183
organism: Escherichia coli

Reference/HMDB HMDB0003403
type: UnificationXref
id: HMDB0003403
db: HMDB

Water
type: SmallMolecule
entity reference: Water

Reference/GENE ONTOLOGY GO 0043165
type: UnificationXref
id: GO:0043165
db: GENE ONTOLOGY

Reference/PubChem-compound 123912
type: UnificationXref
id: 123912
db: PubChem-compound

Reference/HMDB HMDB0000258
type: UnificationXref
id: HMDB0000258
db: HMDB

D-Glucose
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Glucose

ChemicalStructure/PW C000177
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001024
type: ChemicalStructure
structure format: SMILES

Reference/CAS 492-61-5
type: UnificationXref
id: 492-61-5
db: CAS

Reference/ChEBI CHEBI 28087
type: UnificationXref
id: CHEBI:28087
db: ChEBI

PTS system glucose-specific EIICB component
type: Protein
cellular location: Inner Membrane
entity reference: PTS system glucose-specific EIICB component

Compound/PW C001851 Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Reference/PubChem-compound 10991489
type: UnificationXref
id: 10991489
db: PubChem-compound

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/HMDB HMDB0001342
type: UnificationXref
id: HMDB0001342
db: HMDB

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

ChemicalStructure/PW C042934
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C03319
type: UnificationXref
id: C03319
db: KEGG Compound

Compound/PW C001420 Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Dextrin
type: SmallMoleculeReference
xref: Reference/ChemSpider 56445
xref: Reference/KEGG Compound C00721
xref: Reference/PubChem-compound 62698
xref: Reference/HMDB HMDB0006857
xref: Reference/CAS 9004-53-9
chemical formula: C18H32O16
molecular weight: 504.16904
structure: ChemicalStructure/PW C002975

Reference/ChEBI CHEBI 18283
type: UnificationXref
id: CHEBI:18283
db: ChEBI

dTDP-β-L-rhamnose
type: SmallMoleculeReference
xref: Reference/CAS 2147-59-3
xref: Reference/KEGG Compound C03319
xref: Reference/ChemSpider 388998
xref: Reference/ChEBI CHEBI 35452
xref: Reference/PubChem-compound 439975
xref: Reference/BioCyc DTDP-RHAMNOSE
xref: Reference/HMDB HMDB0006354
chemical formula: C16H26N2O15P2
molecular weight: 548.0809
structure: ChemicalStructure/PW C002734

Reference/CAS 2140-58-1
type: UnificationXref
id: 2140-58-1
db: CAS

Mannose permease IID component
type: ProteinReference
xref: Reference/UniProt P69805
organism: Escherichia coli

Mannose permease IIC component
type: ProteinReference
xref: Reference/UniProt P69801
organism: Escherichia coli

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Sucrose
type: SmallMolecule
cellular location: Cytosol
entity reference: Sucrose

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Compound/PW C000193 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucose
stoichiometric coefficient: 1.0

Hexose phosphate transport protein
type: ProteinReference
xref: Reference/UniProt P0AGC0

Reference/CAS 9004-53-9
type: UnificationXref
id: 9004-53-9
db: CAS

ChemicalStructure/PW C001035
type: ChemicalStructure
structure format: SMILES

Uridine 5'-diphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17659
xref: Reference/PubChem-compound 6031
xref: Reference/CAS 58-98-0
xref: Reference/HMDB HMDB0000295
xref: Reference/KEGG Compound C00015
xref: Reference/ChemSpider 5809
xref: Reference/BioCyc UDP
chemical formula: C9H14N2O12P2
molecular weight: 404.0022
structure: ChemicalStructure/PW C000201

Reference/PubChem-compound 64689
type: UnificationXref
id: 64689
db: PubChem-compound

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChEBI CHEBI 4170
type: UnificationXref
id: CHEBI:4170
db: ChEBI

Dextrin
type: SmallMolecule
entity reference: Dextrin

Reference/ChemSpider 110443
type: UnificationXref
id: 110443
db: ChemSpider

Reference/HMDB HMDB0001124
type: UnificationXref
id: HMDB0001124
db: HMDB

ChemicalStructure/PW C000395
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001000
type: ChemicalStructure
structure format: SMILES

Cytoplasmic trehalase
type: Protein
entity reference: Cytoplasmic trehalase

2.7.1.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001906 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000395 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: β-D-Glucose 6-phosphate
spontaneous: false
EC number: 2.7.1.2
left: Adenosine triphosphate
left: β-D-Glucose
name: Adenosine triphosphate + β-D-Glucose → Adenosine diphosphate + Hydrogen Ion + β-D-Glucose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C000878 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Trehalose 6-phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00182
type: UnificationXref
id: C00182
db: KEGG Compound

Reference/CAS 492-62-6
type: UnificationXref
id: 492-62-6
db: CAS

Compound/PW C001851 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Reference/BioCyc MALTOTRIOSE
type: UnificationXref
id: MALTOTRIOSE
db: BioCyc

Reference/SMPDB SMP0000958
type: UnificationXref
id: SMP0000958
db: SMPDB

Compound/PW C000107 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Maltose
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/BioCyc MALTOTETRAOSE
type: UnificationXref
id: MALTOTETRAOSE
db: BioCyc

Glycogen phosphorylase
type: Protein
entity reference: Glycogen phosphorylase

Protein/7464 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphocarrier protein HPr
stoichiometric coefficient: 1.0

Reference/BioCyc DTDP-D-GLUCOSE
type: UnificationXref
id: DTDP-D-GLUCOSE
db: BioCyc

Reference/UniProt P0A6T1
type: UnificationXref
id: P0A6T1
db: UniProt

Amylose
type: SmallMolecule
entity reference: Amylose

Reference/CAS 9005-82-7
type: UnificationXref
id: 9005-82-7
db: CAS

α-D-Glucose
type: SmallMolecule
cellular location: Cytosol
entity reference: α-D-Glucose

Amylose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003403
xref: Reference/CAS 9005-82-7
xref: Reference/KEGG Compound C00718
xref: Reference/PubChem-compound 53477771
xref: Reference/ChEBI CHEBI 28102
chemical formula: (C12H20O11)nC2H6
structure: ChemicalStructure/PW C001872

Compound/PW C001024/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-D-glucose
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000163
type: UnificationXref
id: HMDB0000163
db: HMDB

Reference/HMDB HMDB0000286
type: UnificationXref
id: HMDB0000286
db: HMDB

maltose ABC transporter
type: Complex
component stoichiometry: Protein/6683 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Maltose/maltodextrin import ATP-binding protein MalK
component: Maltose-binding periplasmic protein
component: Maltose transport system permease protein malF
component: Maltose transport system permease protein malG

β-D-Glucose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: β-D-Glucose

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChemSpider 388711
type: UnificationXref
id: 388711
db: ChemSpider

D-Maltose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 47937
xref: Reference/BioCyc MALTOSE
xref: Reference/KEGG Compound C00208
xref: Reference/ChemSpider 9166684
xref: Reference/HMDB HMDB0000163
xref: Reference/CAS 69-79-4
xref: Reference/PubChem-compound 10991489
chemical formula: C12H22O11
molecular weight: 342.1162
structure: ChemicalStructure/PW C000107

Fructokinase
type: Protein
cellular location: Cytosol
entity reference: Fructokinase

Reference/PathWhiz PW000941
type: UnificationXref
id: PW000941
db: PathWhiz

ChemicalStructure/PW C040941
type: ChemicalStructure
structure format: SMILES
structure data: OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/CAS 58-98-0
type: UnificationXref
id: 58-98-0
db: CAS

Reference/UniProt P68183
type: UnificationXref
id: P68183
db: UniProt

Reference/ChEBI CHEBI 18077
type: UnificationXref
id: CHEBI:18077
db: ChEBI

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/UniProt P68187
type: UnificationXref
id: P68187
db: UniProt

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Glycogen debranching enzyme
type: Protein
entity reference: Glycogen debranching enzyme

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Reference/KEGG Compound C01172
type: UnificationXref
id: C01172
db: KEGG Compound

Compound/PW C042898 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-glucose 1-phosphate
stoichiometric coefficient: 1.0

Transport433
type: Transport
participant stoichiometry: Compound/PW C001906 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001906 Periplasmic Space/Stoichiometry/1.0
right: Phosphate
right: β-D-Glucose 6-phosphate
spontaneous: false
left: β-D-Glucose 6-phosphate
left: Phosphate
name: β-D-Glucose 6-phosphate (→), Phosphate (←) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0000295
type: UnificationXref
id: HMDB0000295
db: HMDB

Transport432
type: Transport
participant stoichiometry: Compound/PW C040941 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Periplasmic Space/Stoichiometry/1.0
right: Phosphate
right: β-D-fructofuranose 6-phosphate
spontaneous: false
left: Phosphate
left: β-D-fructofuranose 6-phosphate
name: β-D-fructofuranose 6-phosphate (→), Phosphate (←) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0001262
type: UnificationXref
id: HMDB0001262
db: HMDB

Reference/ChemSpider 5809
type: UnificationXref
id: 5809
db: ChemSpider

Transport434
type: Transport
participant stoichiometry: Compound/PW C000077 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000077 Periplasmic Space/Stoichiometry/1.0
right: D-Glucose
spontaneous: false
left: D-Glucose
name: D-Glucose (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 45868
type: UnificationXref
id: CHEBI:45868
db: ChEBI

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Alpha,alpha-trehalose-phosphate synthase [UDP-forming]
type: Protein
cellular location: Cytosol
entity reference: Alpha,alpha-trehalose-phosphate synthase [UDP-forming]

phosphoglucose isomerase
type: Complex
component stoichiometry: Protein/6010 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Glucose-6-phosphate isomerase

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

α,α-trehalose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: α,α-trehalose

Reference/KEGG Compound C00089
type: UnificationXref
id: C00089
db: KEGG Compound

4-alpha-glucanotransferase
type: Protein
entity reference: 4-alpha-glucanotransferase

Protein/Generic214 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: [PTS enzyme I]-L-histidine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00092
type: UnificationXref
id: C00092
db: KEGG Compound

Reference/CAS 2147-59-3
type: UnificationXref
id: 2147-59-3
db: CAS

Reference/ChemSpider 71358
type: UnificationXref
id: 71358
db: ChemSpider

Compound/PW C040941 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose 6-phosphate
stoichiometric coefficient: 1.0

Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 4167
type: UnificationXref
id: CHEBI:4167
db: ChEBI

Reference/CAS 2255-14-3
type: UnificationXref
id: 2255-14-3
db: CAS

dTDP-4-dehydrorhamnose 3,5-epimerase
type: Protein
entity reference: dTDP-4-dehydrorhamnose 3,5-epimerase

α,α-trehalose
type: SmallMolecule
cellular location: Cytosol
entity reference: α,α-trehalose

Reference/CAS 2196-62-5
type: UnificationXref
id: 2196-62-5
db: CAS

Maltose transport system permease protein malG
type: Protein
cellular location: Inner Membrane
entity reference: Maltose transport system permease protein malG

Reference/ChEBI CHEBI 47937
type: UnificationXref
id: CHEBI:47937
db: ChEBI

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Compound/PW C001851/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Reference/UniProt P61887
type: UnificationXref
id: P61887
db: UniProt

Reference/CAS 56-73-5
type: UnificationXref
id: 56-73-5
db: CAS

Glucose-specific phosphotransferase enzyme IIA component
type: Protein
cellular location: Inner Membrane
entity reference: Glucose-specific phosphotransferase enzyme IIA component

Protein/10364/Stoichiometry/4.0
type: Stoichiometry
physical entity: Glucose-1-phosphate thymidylyltransferase 2
stoichiometric coefficient: 4.0

ChemicalStructure/PW C000077
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/HMDB HMDB0003345
type: UnificationXref
id: HMDB0003345
db: HMDB

Reference/UniProt P13482
type: UnificationXref
id: P13482
db: UniProt

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/HMDB HMDB0006857
type: UnificationXref
id: HMDB0006857
db: HMDB

dTDP-glucose 4,6-dehydratase 2
type: Protein
entity reference: dTDP-glucose 4,6-dehydratase 2

5.1.3.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C044520/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042658/Stoichiometry/1.0
right: dTDP-4-dehydro-β-L-rhamnose
spontaneous: false
EC number: 5.1.3.13
left: dTDP-4-dehydro-6-deoxy-D-glucose
name: dTDP-4-dehydro-6-deoxy-D-glucose → dTDP-4-dehydro-β-L-rhamnose
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000193
type: ChemicalStructure
structure format: SMILES

1.1.1.133
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C044520 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002734 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: NADP
right: dTDP-β-L-rhamnose
spontaneous: false
EC number: 1.1.1.133
left: dTDP-4-dehydro-β-L-rhamnose
left: Hydrogen Ion
left: NADPH
name: Hydrogen Ion + NADPH + dTDP-4-dehydro-β-L-rhamnose → NADP + dTDP-β-L-rhamnose
conversion direction: LEFT_TO_RIGHT

β-D-Glucose
type: SmallMolecule
cellular location: Cytosol
entity reference: β-D-Glucose

Compound/PW C001083/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

debranched limit dextrin
type: SmallMoleculeReference

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/ChEBI CHEBI 57634
type: UnificationXref
id: CHEBI:57634
db: ChEBI

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

D-Maltose
type: SmallMolecule
entity reference: D-Maltose

Reference/KEGG Compound C02052
type: UnificationXref
id: C02052
db: KEGG Compound

Adenosine diphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine diphosphate

Reference/ChEBI CHEBI 15903
type: UnificationXref
id: CHEBI:15903
db: ChEBI

Compound/PW C042934 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: α,α-trehalose
stoichiometric coefficient: 1.0

Putative beta-phosphoglucomutase
type: Protein
cellular location: Cytosol
entity reference: Putative beta-phosphoglucomutase

Reference/HMDB HMDB0001296
type: UnificationXref
id: HMDB0001296
db: HMDB

Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc SUCROSE
type: UnificationXref
id: SUCROSE
db: BioCyc

Reference/BioCyc CPD-535
type: UnificationXref
id: CPD-535
db: BioCyc

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/UniProt P27830
type: UnificationXref
id: P27830
db: UniProt

α,α-trehalose
type: SmallMolecule
entity reference: α,α-trehalose

Reference/ChEBI CHEBI 35452
type: UnificationXref
id: CHEBI:35452
db: ChEBI

Glycogen synthase
type: Protein
entity reference: Glycogen synthase

ReactionCatalysis3503
type: Catalysis
controller: Maltodextrin glucosidase
controlled: 3.2.1.20
control type: ACTIVATION

D-Maltose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: D-Maltose

ReactionCatalysis3504
type: Catalysis
controller: 4-alpha-glucanotransferase
controlled: 2.4.1.25
control type: ACTIVATION

ReactionCatalysis3501
type: Catalysis
controller: Glycogen debranching enzyme
controlled: 3.2.1.-
control type: ACTIVATION

dTDP-D-glucose
type: SmallMolecule
entity reference: dTDP-D-glucose

Maltotetraose
type: SmallMoleculeReference
xref: Reference/KEGG Compound C02052
xref: Reference/ChemSpider 388711
xref: Reference/ChEBI CHEBI 61988
xref: Reference/CAS 34612-38-9
xref: Reference/BioCyc MALTOTETRAOSE
xref: Reference/PubChem-compound 439639
xref: Reference/HMDB HMDB0001296
chemical formula: C24H42O21
molecular weight: 666.22186
structure: ChemicalStructure/PW C001000

ReactionCatalysis3502
type: Catalysis
controller: maltodextrin phosphorylase
controlled: Reaction3522
control type: ACTIVATION

Sucrose
type: SmallMolecule
entity reference: Sucrose

ReactionCatalysis3505
type: Catalysis
controller: Glucokinase
controlled: Reaction3525
control type: ACTIVATION

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Glucokinase
type: Protein
entity reference: Glucokinase

β-D-Glucose
type: SmallMoleculeReference
xref: Reference/PubChem-compound 64689
xref: Reference/ChemSpider 58238
xref: Reference/HMDB HMDB0000516
xref: Reference/KEGG Compound C00221
xref: Reference/CAS 492-61-5
xref: Reference/ChEBI CHEBI 15903
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000395

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

ReactionCatalysis3500
type: Catalysis
controller: glycogen phosphorylase
controlled: 2.4.1.1
control type: ACTIVATION

Reference/PubChem-compound 439709
type: UnificationXref
id: 439709
db: PubChem-compound

Reference/UniProt P37745
type: UnificationXref
id: P37745
db: UniProt

Reference/UniProt P62601
type: UnificationXref
id: P62601
db: UniProt

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/UniProt P15977
type: UnificationXref
id: P15977
db: UniProt

Reference/BioCyc GALACTOSE-1P
type: UnificationXref
id: GALACTOSE-1P
db: BioCyc

Compound/PW C000143 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Protein/5823 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Maltodextrin phosphorylase
stoichiometric coefficient: 2.0

trehalose PTS permease
type: Complex
component stoichiometry: Protein/6555 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: PTS system trehalose-specific EIIBC component
component: Glucose-specific phosphotransferase enzyme IIA component

Reference/ChEBI CHEBI 61988
type: UnificationXref
id: CHEBI:61988
db: ChEBI

Compound/PW C000975 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Maltotriose
stoichiometric coefficient: 1.0

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/HMDB HMDB0000660
type: UnificationXref
id: HMDB0000660
db: HMDB

PTS system maltose- and glucose-specific EIICB component
type: Protein
entity reference: PTS system maltose- and glucose-specific EIICB component

Compound/PW C044520/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-4-dehydro-β-L-rhamnose
stoichiometric coefficient: 1.0

Reference/UniProt P00490
type: UnificationXref
id: P00490
db: UniProt

Compound/PW C042898 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-glucose 1-phosphate
stoichiometric coefficient: 1.0

D-Glucose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: D-Glucose

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Compound/PW C001906 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

Compound/PW C000975 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Maltotriose
stoichiometric coefficient: 1.0

Maltotetraose
type: SmallMolecule
entity reference: Maltotetraose

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/HMDB HMDB0001401
type: UnificationXref
id: HMDB0001401
db: HMDB

Compound/PW C042663/Stoichiometry/1.0
type: Stoichiometry
physical entity: UDP-galactose
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 27931
type: UnificationXref
id: CHEBI:27931
db: ChEBI

β-D-Glucose
type: SmallMolecule
entity reference: β-D-Glucose

Protein/6010 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glucose-6-phosphate isomerase
stoichiometric coefficient: 2.0

Compound/PW C040941 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose 6-phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 439975
type: UnificationXref
id: 439975
db: PubChem-compound

Reference/CAS 1109-28-0
type: UnificationXref
id: 1109-28-0
db: CAS

Maltodextrin phosphorylase
type: ProteinReference
xref: Reference/UniProt P00490

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

α,α-trehalose
type: SmallMoleculeReference
xref: Reference/PubChem-compound 7427
xref: Reference/ChEBI CHEBI 16551
chemical formula: C12H22O11
molecular weight: 342.1162
structure: ChemicalStructure/PW C042934

Reference/PubChem-compound 5988
type: UnificationXref
id: 5988
db: PubChem-compound

maltodextrin phosphorylase
type: Complex
component stoichiometry: Protein/5823 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Maltodextrin phosphorylase

ChemicalStructure/PW C002975
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002734
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

Amylose
type: SmallMolecule
cellular location: Cytosol
entity reference: Amylose

Compound/PW C001872/Stoichiometry/1.0
type: Stoichiometry
physical entity: Amylose
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000201
type: ChemicalStructure
structure format: SMILES

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Reference/UniProt P36672
type: UnificationXref
id: P36672
db: UniProt

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Reference/UniProt P37760
type: UnificationXref
id: P37760
db: UniProt

mannose PTS permease
type: Complex
component stoichiometry: Protein/6697 Inner Membrane/Stoichiometry/2.0
component stoichiometry: Protein/7147 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Mannose permease IIC component
component: Mannose permease IID component
component: PTS system mannose-specific EIIAB component

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/PathWhiz PW000785
type: UnificationXref
id: PW000785
db: PathWhiz

Reference/ChEBI CHEBI 57684
type: UnificationXref
id: CHEBI:57684
db: ChEBI

Compound/PW C001906 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

Trehalose 6-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Trehalose 6-phosphate

Uridine diphosphate glucose
type: SmallMoleculeReference
xref: Reference/BioCyc UDP-GLUCOSE
xref: Reference/KEGG Compound C00029
xref: Reference/PubChem-compound 53477679
xref: Reference/CAS 133-89-1
xref: Reference/HMDB HMDB0000286
chemical formula: C15H24N2O17P2
molecular weight: 566.055
structure: ChemicalStructure/PW C000193

Reference/BioCyc UDP-GLUCOSE
type: UnificationXref
id: UDP-GLUCOSE
db: BioCyc

Reference/UniProt P69797
type: UnificationXref
id: P69797
db: UniProt

Mannose permease IID component
type: Protein
cellular location: Inner Membrane
entity reference: Mannose permease IID component

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

galactose-1-phosphate uridylyltransferase
type: Complex
component stoichiometry: Protein/5964/Stoichiometry/2.0
component: Galactose-1-phosphate uridylyltransferase

maltodextrin phosphorylase
type: Complex
component stoichiometry: Protein/5823/Stoichiometry/2.0
component: Maltodextrin phosphorylase

Reference/PubChem-compound 439639
type: UnificationXref
id: 439639
db: PubChem-compound

D-Glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000122
xref: Reference/PubChem-compound 5793
xref: Reference/CAS 2280-44-6
xref: Reference/ChemSpider 5589
xref: Reference/ChEBI CHEBI 4167
xref: Reference/BioCyc GLC
xref: Reference/KEGG Compound C00031
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000077

debranched limit dextrin
type: SmallMolecule
entity reference: debranched limit dextrin

Hydrogen Ion
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Hydrogen Ion

Compound/PW C000077 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glucose
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc GLC
type: UnificationXref
id: GLC
db: BioCyc

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: Reference/UniProt P09148

Protein/5964/Stoichiometry/2.0
type: Stoichiometry
physical entity: Galactose-1-phosphate uridylyltransferase
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 35248
type: UnificationXref
id: CHEBI:35248
db: ChEBI

Reference/UniProt P69783
type: UnificationXref
id: P69783
db: UniProt

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Maltodextrin phosphorylase
type: Protein
cellular location: Cytosol
entity reference: Maltodextrin phosphorylase

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P69786
type: UnificationXref
id: P69786
db: UniProt

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

glycogen phosphorylase
type: Complex
component stoichiometry: Protein/6207/Stoichiometry/2.0
component: Glycogen phosphorylase

Hexose phosphate transport protein
type: Protein
entity reference: Hexose phosphate transport protein

Mannose permease IIC component
type: Protein
cellular location: Inner Membrane
entity reference: Mannose permease IIC component

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

β-D-fructofuranose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57634
chemical formula: C6H11O9P
molecular weight: 258.01517
structure: ChemicalStructure/PW C040941

Reference/UniProt P09148
type: UnificationXref
id: P09148
db: UniProt

Periplasmic trehalase
type: Protein
cellular location: Outer Membrane
entity reference: Periplasmic trehalase

ChemicalStructure/PW C000107
type: ChemicalStructure
structure format: SMILES

Maltotriose
type: SmallMolecule
cellular location: Cytosol
entity reference: Maltotriose

Compound/PW C000605 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycogen
stoichiometric coefficient: 1.0

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

α-D-glucose-1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: α-D-glucose-1-phosphate

Uridine diphosphate glucose
type: SmallMolecule
entity reference: Uridine diphosphate glucose

Reference/PubChem-compound 5958
type: UnificationXref
id: 5958
db: PubChem-compound

dTDP-D-glucose
type: SmallMoleculeReference
xref: Reference/ChemSpider 388455
xref: Reference/KEGG Compound C00842
xref: Reference/PubChem-compound 439324
xref: Reference/HMDB HMDB0001328
xref: Reference/CAS 2196-62-5
xref: Reference/ChEBI CHEBI 35248
xref: Reference/BioCyc DTDP-D-GLUCOSE
chemical formula: C16H26N2O16P2
molecular weight: 564.07574
structure: ChemicalStructure/PW C001024

D-Glucose
type: SmallMolecule
entity reference: D-Glucose

Reference/HMDB HMDB0001328
type: UnificationXref
id: HMDB0001328
db: HMDB

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Sucrose
type: SmallMoleculeReference
xref: Reference/BioCyc SUCROSE
xref: Reference/CAS 57-50-1
xref: Reference/HMDB HMDB0000258
xref: Reference/ChemSpider 5768
xref: Reference/KEGG Compound C00089
xref: Reference/PubChem-compound 5988
xref: Reference/ChEBI CHEBI 17992
chemical formula: C12H22O11
molecular weight: 342.1162
structure: ChemicalStructure/PW C000177

Protein/5823/Stoichiometry/2.0
type: Stoichiometry
physical entity: Maltodextrin phosphorylase
stoichiometric coefficient: 2.0

TransportCatalysis377
type: Catalysis
controller: PTS system maltose- and glucose-specific EIICB component
controlled: Transport434
control type: ACTIVATION

TransportCatalysis376
type: Catalysis
controller: Hexose phosphate transport protein
controlled: Transport433
control type: ACTIVATION

β-D-Glucose 6-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: β-D-Glucose 6-phosphate

TransportCatalysis375
type: Catalysis
controller: Hexose phosphate transport protein
controlled: Transport432
control type: ACTIVATION

β-D-Glucose 6-phosphate
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: β-D-Glucose 6-phosphate

Reference/ChEBI CHEBI 15751
type: UnificationXref
id: CHEBI:15751
db: ChEBI

α-D-Glucose
type: SmallMolecule
cellular location: Outer Membrane
entity reference: α-D-Glucose

Reference/HMDB HMDB0000122
type: UnificationXref
id: HMDB0000122
db: HMDB

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Thymidine 5'-triphosphate
type: SmallMolecule
entity reference: Thymidine 5'-triphosphate

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Thymidine 5'-triphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00459
xref: Reference/CAS 365-08-2
xref: Reference/ChEBI CHEBI 18077
xref: Reference/ChemSpider 58493
xref: Reference/PubChem-compound 64968
xref: Reference/HMDB HMDB0001342
xref: Reference/BioCyc TTP
chemical formula: C10H17N2O14P3
molecular weight: 481.98926
structure: ChemicalStructure/PW C001035

Reference/UniProt P36871
type: UnificationXref
id: P36871
db: UniProt

Reference/ChEBI CHEBI 17925
type: UnificationXref
id: CHEBI:17925
db: ChEBI

Compound/PW C000395 Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose
stoichiometric coefficient: 1.0

Reference/ChemSpider 56445
type: UnificationXref
id: 56445
db: ChemSpider

Reference/UniProt P76041
type: UnificationXref
id: P76041
db: UniProt

Compound/PW C000605/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycogen
stoichiometric coefficient: 1.0

Compound/PW C000517/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Fructose
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine triphosphate

D-Maltose
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Maltose

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

β-D-Glucose
type: SmallMolecule
cellular location: Outer Membrane
entity reference: β-D-Glucose

dTDP-4-dehydro-6-deoxy-D-glucose
type: SmallMolecule
entity reference: dTDP-4-dehydro-6-deoxy-D-glucose

ChemicalStructure/PW C000605
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc UDP
type: UnificationXref
id: UDP
db: BioCyc

Compound/PW C000517 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Fructose
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 28645
type: UnificationXref
id: CHEBI:28645
db: ChEBI

Outer Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0043165

Phosphate
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Phosphate

ReactionCoupledTransport156
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000107 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
right: D-Maltose
right: Phosphate
right: Adenosine diphosphate
right: Hydrogen Ion
spontaneous: false
left: Water
left: D-Maltose
left: Adenosine triphosphate
name: Adenosine triphosphate + D-Maltose + Water → Adenosine diphosphate + D-Maltose + Hydrogen Ion + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 9005-79-2
type: UnificationXref
id: 9005-79-2
db: CAS

3.6.3.19
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C001000 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
right: Phosphate
right: Adenosine diphosphate
right: Maltotetraose
right: Hydrogen Ion
spontaneous: false
EC number: 3.6.3.19
left: Water
left: Adenosine triphosphate
left: Maltotetraose
name: Adenosine triphosphate + Maltotetraose + Water → Adenosine diphosphate + Hydrogen Ion + Maltotetraose + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00718
type: UnificationXref
id: C00718
db: KEGG Compound

ReactionCoupledTransport155
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000975 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
right: Maltotriose
right: Phosphate
right: Adenosine diphosphate
right: Hydrogen Ion
spontaneous: false
left: Maltotriose
left: Water
left: Adenosine triphosphate
name: Adenosine triphosphate + Maltotriose + Water → Adenosine diphosphate + Hydrogen Ion + Maltotriose + Phosphate
conversion direction: LEFT_TO_RIGHT

ReactionCoupledTransport152
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000077 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042898 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/Generic214 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/Generic213 Inner Membrane/Stoichiometry/1.0
right: [PTS enzyme I]-L-histidine
right: β-D-glucose 1-phosphate
spontaneous: false
left: D-Glucose
left: [PTS enzyme I]-Nπ-phospho-L-histidine
name: D-Glucose + [PTS enzyme I]-Nπ-phospho-L-histidine → [PTS enzyme I]-L-histidine + β-D-glucose 1-phosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.69
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000878 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042934 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/7464 Inner Membrane/Stoichiometry/1.0
right: Phosphocarrier protein HPr
right: Trehalose 6-phosphate
spontaneous: false
EC number: 2.7.1.69
left: Phosphocarrier protein HPr
left: α,α-trehalose
name: HPr - phosphorylated + α,α-trehalose → HPr + Trehalose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00092
xref: Reference/BioCyc GLC-6-P
xref: Reference/HMDB HMDB0001401
xref: Reference/PubChem-compound 5958
xref: Reference/ChemSpider 5743
xref: Reference/CAS 56-73-5
xref: Reference/ChEBI CHEBI 4170
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001083

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/HMDB HMDB0006354
type: UnificationXref
id: HMDB0006354
db: HMDB

Compound/PW C000975/Stoichiometry/1.0
type: Stoichiometry
physical entity: Maltotriose
stoichiometric coefficient: 1.0

Phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Phosphate

Reference/KEGG Compound C00721
type: UnificationXref
id: C00721
db: KEGG Compound

Reference/KEGG Compound C00842
type: UnificationXref
id: C00842
db: KEGG Compound

Compound/PW C000077 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glucose
stoichiometric coefficient: 1.0

4.2.1.46
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042658/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001024/Stoichiometry/1.0
right: Water
right: dTDP-4-dehydro-6-deoxy-D-glucose
spontaneous: false
EC number: 4.2.1.46
left: dTDP-D-glucose
name: dTDP-D-glucose → Water + dTDP-4-dehydro-6-deoxy-D-glucose
conversion direction: LEFT_TO_RIGHT

Glucose-1-phosphate thymidylyltransferase 2
type: Protein
entity reference: Glucose-1-phosphate thymidylyltransferase 2

Glucose-1-phosphate adenylyltransferase
type: Protein
entity reference: Glucose-1-phosphate adenylyltransferase

Putative sucrose phosphorylase
type: ProteinReference
xref: Reference/UniProt P76041

ChemicalStructure/PW C000975
type: ChemicalStructure
structure format: SMILES

Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/ChEBI CHEBI 17992
type: UnificationXref
id: CHEBI:17992
db: ChEBI

β-D-fructofuranose 6-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: β-D-fructofuranose 6-phosphate

Phosphoglucomutase-1
type: ProteinReference
xref: Reference/UniProt P36871

Reference/BioCyc DTDP-RHAMNOSE
type: UnificationXref
id: DTDP-RHAMNOSE
db: BioCyc

Reference/UniProt P0AGC0
type: UnificationXref
id: P0AGC0
db: UniProt

Compound/PW C001000/Stoichiometry/1.0
type: Stoichiometry
physical entity: Maltotetraose
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Compound/PW C000395 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose
stoichiometric coefficient: 1.0

ReactionCoupledTransport144
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C040941 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041111 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/7464 Inner Membrane/Stoichiometry/1.0
right: Phosphocarrier protein HPr
right: β-D-fructofuranose 6-phosphate
spontaneous: false
left: Phosphocarrier protein HPr
left: β-D-fructofuranose
name: HPr - phosphorylated + β-D-fructofuranose → HPr + β-D-fructofuranose 6-phosphate
conversion direction: LEFT_TO_RIGHT

dTDP-4-dehydrorhamnose reductase
type: Protein
cellular location: Cytosol
entity reference: dTDP-4-dehydrorhamnose reductase

Reference/PubChem-compound 439427
type: UnificationXref
id: 439427
db: PubChem-compound

Reference/UniProt P77366
type: UnificationXref
id: P77366
db: UniProt

Water
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Water

D-Fructose
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Fructose

Compound/PW C041033 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-glucose-1-phosphate
stoichiometric coefficient: 1.0

Glucokinase
type: Protein
cellular location: Cytosol
entity reference: Glucokinase

Compound/PW C001906 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 5589
type: UnificationXref
id: 5589
db: ChemSpider

Compound/Generic224/Stoichiometry/1.0
type: Stoichiometry
physical entity: debranched limit dextrin
stoichiometric coefficient: 1.0

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

β-D-Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: β-D-Glucose 6-phosphate

β-D-fructofuranose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: β-D-fructofuranose 6-phosphate

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Protein/6207/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glycogen phosphorylase
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 17719
type: UnificationXref
id: CHEBI:17719
db: ChEBI

Glucose 6-phosphate
type: SmallMolecule
entity reference: Glucose 6-phosphate

ReactionCatalysis3488
type: Catalysis
controller: maltodextrin phosphorylase
controlled: 2.4.1.1
control type: ACTIVATION

ReactionCatalysis3486
type: Catalysis
controller: Maltodextrin glucosidase
controlled: 3.2.1.20
control type: ACTIVATION

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

ReactionCatalysis3487
type: Catalysis
controller: Fructokinase
controlled: Reaction3505
control type: ACTIVATION

Reference/KEGG Compound C01835
type: UnificationXref
id: C01835
db: KEGG Compound

Maltose/maltodextrin import ATP-binding protein MalK
type: Protein
cellular location: Inner Membrane
entity reference: Maltose/maltodextrin import ATP-binding protein MalK

Compound/PW C001000 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Maltotetraose
stoichiometric coefficient: 1.0

D-Glucose
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: D-Glucose

Reference/ChEBI CHEBI 17973
type: UnificationXref
id: CHEBI:17973
db: ChEBI

β-D-glucose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57684
chemical formula: C5H9O9P
molecular weight: 243.99951
structure: ChemicalStructure/PW C042898

ReactionCatalysis3491
type: Catalysis
controller: glucose-1-phosphate adenylyltransferase
controlled: 2.7.7.27
control type: ACTIVATION

ReactionCatalysis3492
type: Catalysis
controller: Glycogen synthase
controlled: 2.4.1.21
control type: ACTIVATION

Compound/PW C000077/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glucose
stoichiometric coefficient: 1.0

UDP-galactose
type: SmallMolecule
entity reference: UDP-galactose

dTDP-4-dehydro-6-deoxy-D-glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0060081
chemical formula: C16H24N2O15P2
molecular weight: 546.0652
structure: ChemicalStructure/PW C042658

ReactionCatalysis3490
type: Catalysis
controller: Phosphoglucomutase-1
controlled: Reaction3510
control type: ACTIVATION

Trehalose-phosphate phosphatase
type: ProteinReference
xref: Reference/UniProt P31678
organism: BiologicalState304

Reference/CAS 69-79-4
type: UnificationXref
id: 69-79-4
db: CAS

Alpha,alpha-trehalose-phosphate synthase [UDP-forming]
type: ProteinReference
xref: Reference/UniProt P31677
organism: BiologicalState304

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/BioCyc GLC-6-P
type: UnificationXref
id: GLC-6-P
db: BioCyc

ReactionCatalysis3259
type: Catalysis
controller: Glucokinase
controlled: 2.7.1.2
control type: ACTIVATION

Reference/PubChem-compound 439324
type: UnificationXref
id: 439324
db: PubChem-compound

ReactionCatalysis3495
type: Catalysis
controller: Glycogen debranching enzyme
controlled: 3.2.1.-
control type: ACTIVATION

ReactionCatalysis3496
type: Catalysis
controller: Cytoplasmic trehalase
controlled: 3.2.1.28
control type: ACTIVATION

ReactionCatalysis3493
type: Catalysis
controller: Alpha,alpha-trehalose-phosphate synthase [UDP-forming]
controlled: 2.4.1.15
control type: ACTIVATION

Compound/PW C002809/Stoichiometry/1.0
type: Stoichiometry
physical entity: ADP-glucose
stoichiometric coefficient: 1.0

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ReactionCatalysis3494
type: Catalysis
controller: Trehalose-phosphate phosphatase
controlled: 3.1.3.12
control type: ACTIVATION

ReactionCatalysis3499
type: Catalysis
controller: Putative sucrose phosphorylase
controlled: Reaction3519
control type: ACTIVATION

ReactionCatalysis3497
type: Catalysis
controller: Periplasmic trehalase
controlled: 3.2.1.28
control type: ACTIVATION

Glucose-1-phosphate thymidylyltransferase 2
type: ProteinReference
xref: Reference/UniProt P61887

Glucose-1-phosphate adenylyltransferase
type: ProteinReference
xref: Reference/UniProt P0A6V1

Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glucose 6-phosphate

Maltodextrin glucosidase
type: Protein
cellular location: Cytosol
entity reference: Maltodextrin glucosidase

Reaction3519
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000177/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041033/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: Sucrose
right: Phosphate
spontaneous: false
left: D-Fructose
left: α-D-glucose-1-phosphate
name: D-Fructose + α-D-glucose-1-phosphate ↔ Phosphate + Sucrose
conversion direction: REVERSIBLE

Putative beta-phosphoglucomutase
type: ProteinReference
xref: Reference/UniProt P77366
organism: BiologicalState304

β-D-Glucose 6-phosphate
type: SmallMolecule
entity reference: β-D-Glucose 6-phosphate
name: SubPathwayInput

Uridine diphosphate glucose
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine diphosphate glucose

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

β-D-glucose 1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: β-D-glucose 1-phosphate

ReactionCatalysis5967
type: Catalysis
controller: dTDP-4-dehydrorhamnose reductase
controlled: 1.1.1.133
control type: ACTIVATION

ReactionCatalysis5966
type: Catalysis
controller: dTDP-4-dehydrorhamnose 3,5-epimerase
controlled: 5.1.3.13
control type: ACTIVATION

Reference/BioCyc TREHALOSE-6P
type: UnificationXref
id: TREHALOSE-6P
db: BioCyc

glucose-1-phosphate adenylyltransferase
type: Complex
component stoichiometry: Protein/10002/Stoichiometry/4.0
component: Glucose-1-phosphate adenylyltransferase

3.2.1.28
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042934 Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000395 Outer Membrane/Stoichiometry/1.0
right: α-D-Glucose
right: β-D-Glucose
spontaneous: false
EC number: 3.2.1.28
left: α,α-trehalose
left: Water
name: Water + α,α-trehalose → α-D-Glucose + β-D-Glucose
conversion direction: LEFT_TO_RIGHT

3.2.1.28
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000395/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042934/Stoichiometry/1.0
right: β-D-Glucose
right: α-D-Glucose
spontaneous: false
EC number: 3.2.1.28
left: Water
left: α,α-trehalose
name: Water + α,α-trehalose → α-D-Glucose + β-D-Glucose
conversion direction: LEFT_TO_RIGHT

3.2.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000605/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042934/Stoichiometry/1.0
right: α,α-trehalose
spontaneous: false
EC number: 3.2.1.-
left: Glycogen
name: Glycogen ↔ α,α-trehalose
conversion direction: REVERSIBLE

3.1.3.12
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000878 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042934 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: α,α-trehalose
spontaneous: false
EC number: 3.1.3.12
left: Trehalose 6-phosphate
left: Water
name: Trehalose 6-phosphate + Water → Phosphate + α,α-trehalose
conversion direction: LEFT_TO_RIGHT

2.4.1.15
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000193 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000878 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001083 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000201 Cytosol/Stoichiometry/1.0
right: Trehalose 6-phosphate
right: Hydrogen Ion
right: Uridine 5'-diphosphate
spontaneous: false
EC number: 2.4.1.15
left: Glucose 6-phosphate
left: Uridine diphosphate glucose
name: Glucose 6-phosphate + Uridine diphosphate glucose → Hydrogen Ion + Trehalose 6-phosphate + Uridine 5'-diphosphate
conversion direction: LEFT_TO_RIGHT

2.4.1.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001872/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002809/Stoichiometry/1.0
right: Adenosine diphosphate
right: Amylose
spontaneous: false
EC number: 2.4.1.21
left: ADP-glucose
left: Amylose
name: ADP-glucose + Amylose ↔ Adenosine diphosphate + Amylose
conversion direction: REVERSIBLE

2.7.7.27
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041033/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002809/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: ADP-glucose
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.27
left: α-D-glucose-1-phosphate
left: Hydrogen Ion
left: Adenosine triphosphate
name: Adenosine triphosphate + Hydrogen Ion + α-D-glucose-1-phosphate → ADP-glucose + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis5962
type: Catalysis
controller: dTDP-glucose pyrophosphorylase
controlled: 2.7.7.24
control type: ACTIVATION

Reaction3510
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001083/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041033/Stoichiometry/1.0
right: α-D-glucose-1-phosphate
spontaneous: false
left: Glucose 6-phosphate
name: Glucose 6-phosphate ↔ α-D-glucose-1-phosphate
conversion direction: REVERSIBLE

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reaction3509
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001083/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001906/Stoichiometry/1.0
right: Glucose 6-phosphate
spontaneous: true
left: β-D-Glucose 6-phosphate
name: β-D-Glucose 6-phosphate ↔ Glucose 6-phosphate
conversion direction: REVERSIBLE

Reference/BioCyc MALTOSE
type: UnificationXref
id: MALTOSE
db: BioCyc

2.4.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041033 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001872 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000605 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Glycogen
spontaneous: false
EC number: 2.4.1.1
left: α-D-glucose-1-phosphate
left: Amylose
name: Amylose + α-D-glucose-1-phosphate ↔ Glycogen + Phosphate
conversion direction: REVERSIBLE

PTS system trehalose-specific EIIBC component
type: Protein
cellular location: Inner Membrane
entity reference: PTS system trehalose-specific EIIBC component

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Reference/PubChem-compound 439586
type: UnificationXref
id: 439586
db: PubChem-compound

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001872
type: ChemicalStructure
structure format: SMILES

Maltose transport system permease protein malF
type: Protein
cellular location: Inner Membrane
entity reference: Maltose transport system permease protein malF

ReactionCatalysis3319
type: Catalysis
controller: phosphoglucose isomerase
controlled: 5.3.1.9
control type: ACTIVATION

Reaction3506
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041033 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042898 Cytosol/Stoichiometry/1.0
right: α-D-glucose-1-phosphate
spontaneous: true
left: β-D-glucose 1-phosphate
name: β-D-glucose 1-phosphate → α-D-glucose-1-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 79025
type: UnificationXref
id: 79025
db: PubChem-compound

Reaction3505
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: β-D-fructofuranose 6-phosphate
spontaneous: false
left: D-Fructose
left: Adenosine triphosphate
name: Adenosine triphosphate + D-Fructose → Adenosine diphosphate + Hydrogen Ion + β-D-fructofuranose 6-phosphate
conversion direction: LEFT_TO_RIGHT

3.2.1.20
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000077 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000177 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: D-Fructose
right: D-Glucose
spontaneous: false
EC number: 3.2.1.20
left: Sucrose
left: Water
name: Sucrose + Water ↔ D-Fructose + D-Glucose
conversion direction: REVERSIBLE

ChemicalStructure/PW C044520
type: ChemicalStructure
structure format: SMILES

Maltotetraose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Maltotetraose

Reference/PubChem-compound 5793
type: UnificationXref
id: 5793
db: PubChem-compound

Reference/TAXONOMY 2
type: UnificationXref
id: 2
db: TAXONOMY

ChemicalStructure/PW C002809
type: ChemicalStructure
structure format: SMILES

Fructokinase
type: ProteinReference
xref: Reference/UniProt P23917
organism: BiologicalState304

Maltodextrin phosphorylase
type: Protein
entity reference: Maltodextrin phosphorylase

Protein/6697 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: PTS system mannose-specific EIIAB component
stoichiometric coefficient: 2.0

Protein/6694 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: PTS system glucose-specific EIICB component
stoichiometric coefficient: 2.0

ChemicalStructure/PW C000504
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 16551
type: UnificationXref
id: CHEBI:16551
db: ChEBI

Reference/UniProt P02916
type: UnificationXref
id: P02916
db: UniProt

Compound/PW C000107 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Maltose
stoichiometric coefficient: 1.0

Compound/PW C001872 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Amylose
stoichiometric coefficient: 1.0

Glycogen
type: SmallMolecule
cellular location: Cytosol
entity reference: Glycogen

ReactionCatalysis3682
type: Catalysis
controller: dTDP-glucose 4,6-dehydratase 2
controlled: 4.2.1.46
control type: ACTIVATION

ReactionCatalysis3323
type: Catalysis
controller: galactose-1-phosphate uridylyltransferase
controlled: Reaction3354
control type: ACTIVATION

Reference/UniProt P0AC86
type: UnificationXref
id: P0AC86
db: UniProt

ReactionCatalysis3321
type: Catalysis
controller: Putative beta-phosphoglucomutase
controlled: 5.4.2.6
control type: ACTIVATION

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

α,α-trehalose
type: SmallMolecule
cellular location: Outer Membrane
entity reference: α,α-trehalose

Reference/CAS 57-50-1
type: UnificationXref
id: 57-50-1
db: CAS

Compound/PW C000878 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Trehalose 6-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17659
type: UnificationXref
id: CHEBI:17659
db: ChEBI

Reference/HMDB HMDB0000516
type: UnificationXref
id: HMDB0000516
db: HMDB

Reference/HMDB HMDB0000757
type: UnificationXref
id: HMDB0000757
db: HMDB

[PTS enzyme I]-Nπ-phospho-L-histidine
type: Protein
cellular location: Inner Membrane
entity reference: [PTS enzyme I]-Nπ-phospho-L-histidine

Compound/PW C000395/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose
stoichiometric coefficient: 1.0

PTS system trehalose-specific EIIBC component
type: ProteinReference
xref: Reference/UniProt P36672
organism: Escherichia coli

PTS system mannose-specific EIIAB component
type: Protein
cellular location: Inner Membrane
entity reference: PTS system mannose-specific EIIAB component

Compound/PW C042934 Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: α,α-trehalose
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000517
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O

Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000878
type: ChemicalStructure
structure format: SMILES

Cytoplasmic trehalase
type: ProteinReference
xref: Reference/UniProt P62601

2.4.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000605/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002975/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041033/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: α-D-glucose-1-phosphate
right: Dextrin
spontaneous: false
EC number: 2.4.1.1
left: Glycogen
left: Phosphate
name: Glycogen + Phosphate → Dextrin + α-D-glucose-1-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P69801
type: UnificationXref
id: P69801
db: UniProt

ChemicalStructure/PW C001851
type: ChemicalStructure
structure format: SMILES

Glucose-6-phosphate isomerase
type: Protein
cellular location: Cytosol
entity reference: Glucose-6-phosphate isomerase

Reference/HMDB HMDB0000645
type: UnificationXref
id: HMDB0000645
db: HMDB

Reference/UniProt P69805
type: UnificationXref
id: P69805
db: UniProt

Reaction3525
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001906/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000077/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: β-D-Glucose 6-phosphate
spontaneous: false
left: D-Glucose
left: Adenosine triphosphate
name: Adenosine triphosphate + D-Glucose → Adenosine diphosphate + Hydrogen Ion + β-D-Glucose 6-phosphate
conversion direction: LEFT_TO_RIGHT

2.4.1.25
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000975/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000107/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001000/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000077/Stoichiometry/1.0
right: Maltotetraose
right: D-Glucose
spontaneous: false
EC number: 2.4.1.25
left: D-Maltose
left: Maltotriose
name: D-Maltose + Maltotriose → D-Glucose + Maltotetraose
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C041033
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc ADP-D-GLUCOSE
type: UnificationXref
id: ADP-D-GLUCOSE
db: BioCyc

3.2.1.20
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000107 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000077 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000975 Cytosol/Stoichiometry/1.0
right: D-Glucose
right: D-Maltose
spontaneous: false
EC number: 3.2.1.20
left: Maltotriose
left: Water
name: Maltotriose + Water → D-Glucose + D-Maltose
conversion direction: LEFT_TO_RIGHT

Reaction3522
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000975/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001000/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041033/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: α-D-glucose-1-phosphate
right: Maltotriose
spontaneous: false
left: Maltotetraose
left: Phosphate
name: Maltotetraose + Phosphate → Maltotriose + α-D-glucose-1-phosphate
conversion direction: LEFT_TO_RIGHT

3.2.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001000/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002975/Stoichiometry/1.0
participant stoichiometry: Compound/Generic224/Stoichiometry/1.0
right: Maltotetraose
right: debranched limit dextrin
spontaneous: false
EC number: 3.2.1.-
left: Water
left: Dextrin
name: Dextrin + Water → Maltotetraose + debranched limit dextrin
conversion direction: LEFT_TO_RIGHT