Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/ChemSpider 1001
type: UnificationXref
id: 1001
db: ChemSpider

Tyrosol
type: SmallMolecule
entity reference: Tyrosol

Reference/HMDB HMDB0012199
type: UnificationXref
id: HMDB0012199
db: HMDB

Reference/BioCyc P-HYDROXY-PHENYLPYRUVATE
type: UnificationXref
id: P-HYDROXY-PHENYLPYRUVATE
db: BioCyc

NADH
type: SmallMolecule
entity reference: NADH

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Reference/UniProt P38840
type: UnificationXref
id: P38840
db: UniProt

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Prephenate dehydrogenase [NADP(+)]
type: Protein
entity reference: Prephenate dehydrogenase [NADP(+)]

Reference/UniProt P32178
type: UnificationXref
id: P32178
db: UniProt

Reference/ChemSpider 5833
type: UnificationXref
id: 5833
db: ChemSpider

Aromatic/aminoadipate aminotransferase 1
type: Protein
entity reference: Aromatic/aminoadipate aminotransferase 1

NAD
type: SmallMolecule
entity reference: NAD

Pyruvate decarboxylase isozyme 1
type: Protein
entity reference: Pyruvate decarboxylase isozyme 1

pyruvate decarboxylase 2
type: Protein
entity reference: pyruvate decarboxylase 2

alcohol dehydrogenase subunit I
type: Protein
entity reference: alcohol dehydrogenase subunit I

Pyruvate decarboxylase isozyme 3
type: Protein
entity reference: Pyruvate decarboxylase isozyme 3

alcohol dehydrogenase subunit 2
type: Protein
entity reference: alcohol dehydrogenase subunit 2

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000103
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

Reference/CAS 7339-87-9
type: UnificationXref
id: 7339-87-9
db: CAS

Compound/PW C007748/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chorismate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

chorismate mutase
type: Protein
entity reference: chorismate mutase

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/ChemSpider 954
type: UnificationXref
id: 954
db: ChemSpider

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

ChemicalStructure/PW C007748
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Reference/BioCyc TYR
type: UnificationXref
id: TYR
db: BioCyc

Tyrosine Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/25306
pathway order: PathwayEnzymeReaction/25307
pathway order: PathwayEnzymeReaction/25308
pathway order: PathwayEnzymeReaction/25298
pathway order: PathwayEnzymeReaction/25304
pathway order: PathwayEnzymeReaction/25305
pathway component: Reaction6524
pathway component: 4.1.1.-,4.1.1.1
pathway component: Reaction6526
pathway component: 5.4.99.5
pathway component: ReactionCatalysis6444
pathway component: ReactionCatalysis6443
pathway component: ReactionCatalysis6442
pathway component: ReactionCatalysis6436
pathway component: 1.3.1.13
pathway component: ReactionCatalysis6446
pathway component: Reaction6523
pathway component: ReactionCatalysis6445
xref: Reference/PathWhiz PW002441
xref: Reference/SMPDB SMP0002352
organism: Saccharomyces cerevisiae

pyruvate decarboxylase
type: Complex
component: Pyruvate decarboxylase isozyme 1
component: pyruvate decarboxylase 2
component: Pyruvate decarboxylase isozyme 3

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/ChemSpider 5735
type: UnificationXref
id: 5735
db: ChemSpider

ChemicalStructure/PW C000558
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C(=O)CC1=CC=C(O)C=C1

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChEBI CHEBI 17333
type: UnificationXref
id: CHEBI:17333
db: ChEBI

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Saccharomyces cerevisiae
type: BioSource
xref: Reference/TAXONOMY 4932

Reference/PubChem-compound 1028
type: UnificationXref
id: 1028
db: PubChem-compound

NADP
type: SmallMolecule
entity reference: NADP

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Compound/PW C000558/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-Hydroxyphenylpyruvic acid
stoichiometric coefficient: 1.0

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Reference/ChEBI CHEBI 1879
type: UnificationXref
id: CHEBI:1879
db: ChEBI

Aromatic/aminoadipate aminotransferase 1
type: ProteinReference
xref: Reference/UniProt P53090

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

pyruvate decarboxylase 2
type: ProteinReference
xref: Reference/UniProt P16467

alcohol dehydrogenase subunit I
type: ProteinReference
xref: Reference/UniProt P25377

Pyruvate decarboxylase isozyme 1
type: ProteinReference
xref: Reference/UniProt P06169

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 16977
type: UnificationXref
id: CHEBI:16977
db: ChEBI

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Reference/UniProt P26263
type: UnificationXref
id: P26263
db: UniProt

Reference/UniProt P20049
type: UnificationXref
id: P20049
db: UniProt

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Prephenate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16666
xref: Reference/CAS 126-49-8
xref: Reference/PubChem-compound 1028
xref: Reference/BioCyc PREPHENATE
xref: Reference/KEGG Compound C00254
xref: Reference/HMDB HMDB0012283
xref: Reference/ChemSpider 1001
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007823

Reference/BioCyc PREPHENATE
type: UnificationXref
id: PREPHENATE
db: BioCyc

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Prephenate dehydrogenase [NADP(+)]
type: ProteinReference
xref: Reference/UniProt P20049

Pyruvate decarboxylase isozyme 3
type: ProteinReference
xref: Reference/UniProt P26263

alcohol dehydrogenase subunit 2
type: ProteinReference
xref: Reference/UniProt Q04894

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/PubChem-compound 10393
type: UnificationXref
id: 10393
db: PubChem-compound

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/BioCyc L-ALPHA-ALANINE
type: UnificationXref
id: L-ALPHA-ALANINE
db: BioCyc

Reference/CAS 56-41-7
type: UnificationXref
id: 56-41-7
db: CAS

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

4-Hydroxyphenylacetaldehyde
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440113
xref: Reference/ChEBI CHEBI 15621
xref: Reference/CAS 7339-87-9
xref: Reference/HMDB HMDB0003767
xref: Reference/KEGG Compound C03765
xref: Reference/ChemSpider 389113
xref: Reference/BioCyc CPD-1041
chemical formula: C8H8O2
molecular weight: 136.05243
structure: ChemicalStructure/PW C001966

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Compound/PW C001966/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-Hydroxyphenylacetaldehyde
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P53090
type: UnificationXref
id: P53090
db: UniProt

Reference/UniProt P16467
type: UnificationXref
id: P16467
db: UniProt

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/SMPDB SMP0002352
type: UnificationXref
id: SMP0002352
db: SMPDB

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Reference/ChEBI CHEBI 15621
type: UnificationXref
id: CHEBI:15621
db: ChEBI

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/KEGG Compound C00254
type: UnificationXref
id: C00254
db: KEGG Compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/KEGG Compound C03765
type: UnificationXref
id: C03765
db: KEGG Compound

4-Hydroxyphenylacetaldehyde
type: SmallMolecule
entity reference: 4-Hydroxyphenylacetaldehyde

ChemicalStructure/PW C000105
type: ChemicalStructure
structure format: SMILES
structure data: C[C@H](N)C(O)=O

Reference/KEGG Compound C00251
type: UnificationXref
id: C00251
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/PubChem-compound 5950
type: UnificationXref
id: 5950
db: PubChem-compound

Reaction6524
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000558/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000103/Stoichiometry/1.0
right: Oxoglutaric acid
right: L-Tyrosine
spontaneous: false
left: L-Glutamic acid
left: 4-Hydroxyphenylpyruvic acid
name: 4-Hydroxyphenylpyruvic acid + L-Glutamic acid → L-Tyrosine + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT

Prephenate
type: SmallMolecule
entity reference: Prephenate

4.1.1.-,4.1.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001966/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000558/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Carbon dioxide
right: 4-Hydroxyphenylacetaldehyde
spontaneous: false
EC number: 4.1.1.-,4.1.1.1
left: Hydrogen Ion
left: 4-Hydroxyphenylpyruvic acid
name: 4-Hydroxyphenylpyruvic acid + Hydrogen Ion → 4-Hydroxyphenylacetaldehyde + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

Reaction6526
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001966/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002115/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Tyrosol
spontaneous: false
left: NADH
left: Hydrogen Ion
left: 4-Hydroxyphenylacetaldehyde
name: 4-Hydroxyphenylacetaldehyde + Hydrogen Ion + NADH → NAD + Tyrosol
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Tyrosol
type: SmallMoleculeReference
xref: Reference/KEGG Compound C06044
xref: Reference/PubChem-compound 10393
xref: Reference/HMDB HMDB0004284
xref: Reference/CAS 501-94-0
xref: Reference/ChemSpider 9964
xref: Reference/ChEBI CHEBI 1879
chemical formula: C8H10O2
molecular weight: 138.06808
structure: ChemicalStructure/PW C002115

ReactionCatalysis6436
type: Catalysis
controller: chorismate mutase
controlled: 5.4.99.5
control type: ACTIVATION

1.3.1.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007823/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000558/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
right: Carbon dioxide
right: NADPH
right: 4-Hydroxyphenylpyruvic acid
spontaneous: false
EC number: 1.3.1.13
left: Prephenate
left: NADP
name: NADP + Prephenate → 4-Hydroxyphenylpyruvic acid + Carbon dioxide + NADPH
conversion direction: LEFT_TO_RIGHT

Reaction6523
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000105/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000558/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000103/Stoichiometry/1.0
right: Pyruvic acid
right: L-Tyrosine
spontaneous: false
left: L-Alanine
left: 4-Hydroxyphenylpyruvic acid
name: 4-Hydroxyphenylpyruvic acid + L-Alanine ↔ L-Tyrosine + Pyruvic acid
conversion direction: REVERSIBLE

aromatic amino acid aminotransferase II
type: ProteinReference
xref: Reference/UniProt P38840

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChEBI CHEBI 15999
type: UnificationXref
id: CHEBI:15999
db: ChEBI

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

5.4.99.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007748/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007823/Stoichiometry/1.0
right: Prephenate
spontaneous: false
EC number: 5.4.99.5
left: Chorismate
name: Chorismate → Prephenate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis6444
type: Catalysis
controller: Aromatic/aminoadipate aminotransferase 1
controlled: Reaction6524
control type: ACTIVATION

ReactionCatalysis6443
type: Catalysis
controller: aromatic amino acid aminotransferase II
controlled: Reaction6523
control type: ACTIVATION

ReactionCatalysis6442
type: Catalysis
controller: Prephenate dehydrogenase [NADP(+)]
controlled: 1.3.1.13
control type: ACTIVATION

Reference/HMDB HMDB0004284
type: UnificationXref
id: HMDB0004284
db: HMDB

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Compound/PW C000103/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Tyrosine
stoichiometric coefficient: 1.0

ReactionCatalysis6446
type: Catalysis
controller: alcohol dehydrogenase
controlled: Reaction6526
control type: ACTIVATION

ReactionCatalysis6445
type: Catalysis
controller: pyruvate decarboxylase
controlled: 4.1.1.-,4.1.1.1
control type: ACTIVATION

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Reference/UniProt P25377
type: UnificationXref
id: P25377
db: UniProt

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002115
type: ChemicalStructure
structure format: SMILES
structure data: OCCC1=CC=C(O)C=C1

Reference/KEGG Compound C00041
type: UnificationXref
id: C00041
db: KEGG Compound

Reference/HMDB HMDB0003767
type: UnificationXref
id: HMDB0003767
db: HMDB

Reference/ChEBI CHEBI 16666
type: UnificationXref
id: CHEBI:16666
db: ChEBI

4-Hydroxyphenylpyruvic acid
type: SmallMoleculeReference
xref: Reference/BioCyc P-HYDROXY-PHENYLPYRUVATE
xref: Reference/CAS 156-39-8
xref: Reference/ChEBI CHEBI 15999
xref: Reference/PubChem-compound 979
xref: Reference/HMDB HMDB0000707
xref: Reference/ChemSpider 954
xref: Reference/KEGG Compound C01179
chemical formula: C9H8O4
molecular weight: 180.04225
structure: ChemicalStructure/PW C000558

Chorismate
type: SmallMoleculeReference
xref: Reference/CAS 617-12-9
xref: Reference/BioCyc CPD-9517
xref: Reference/KEGG Compound C00251
xref: Reference/PubChem-compound 12039
xref: Reference/ChEBI CHEBI 17333
xref: Reference/ChemSpider 11542
xref: Reference/HMDB HMDB0012199
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007748

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/BioCyc CPD-1041
type: UnificationXref
id: CPD-1041
db: BioCyc

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Compound/PW C007823/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prephenate
stoichiometric coefficient: 1.0

Reference/ChemSpider 11542
type: UnificationXref
id: 11542
db: ChemSpider

Reference/HMDB HMDB0000707
type: UnificationXref
id: HMDB0000707
db: HMDB

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

4-Hydroxyphenylpyruvic acid
type: SmallMolecule
entity reference: 4-Hydroxyphenylpyruvic acid

Chorismate
type: SmallMolecule
entity reference: Chorismate

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/CAS 617-12-9
type: UnificationXref
id: 617-12-9
db: CAS

Reference/HMDB HMDB0000158
type: UnificationXref
id: HMDB0000158
db: HMDB

Reference/KEGG Compound C06044
type: UnificationXref
id: C06044
db: KEGG Compound

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

Reference/CAS 60-18-4
type: UnificationXref
id: 60-18-4
db: CAS

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/HMDB HMDB0000161
type: UnificationXref
id: HMDB0000161
db: HMDB

chorismate mutase
type: ProteinReference
xref: Reference/UniProt P32178

Reference/BioCyc CPD-9517
type: UnificationXref
id: CPD-9517
db: BioCyc

Reference/PathWhiz PW002441
type: UnificationXref
id: PW002441
db: PathWhiz

L-Alanine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00041
xref: Reference/ChemSpider 5735
xref: Reference/ChEBI CHEBI 16977
xref: Reference/BioCyc L-ALPHA-ALANINE
xref: Reference/HMDB HMDB0000161
xref: Reference/CAS 56-41-7
xref: Reference/PubChem-compound 5950
chemical formula: C3H7NO2
molecular weight: 89.047676
structure: ChemicalStructure/PW C000105

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

L-Tyrosine
type: SmallMoleculeReference
xref: Reference/CAS 60-18-4
xref: Reference/PubChem-compound 6057
xref: Reference/HMDB HMDB0000158
xref: Reference/ChEBI CHEBI 17895
xref: Reference/KEGG Compound C00082
xref: Reference/ChemSpider 5833
xref: Reference/BioCyc TYR
chemical formula: C9H11NO3
molecular weight: 181.0739
structure: ChemicalStructure/PW C000103

Reference/ChemSpider 9964
type: UnificationXref
id: 9964
db: ChemSpider

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/CAS 126-49-8
type: UnificationXref
id: 126-49-8
db: CAS

Compound/PW C000105/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Alanine
stoichiometric coefficient: 1.0

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

Reference/KEGG Compound C00082
type: UnificationXref
id: C00082
db: KEGG Compound

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Compound/PW C002115/Stoichiometry/1.0
type: Stoichiometry
physical entity: Tyrosol
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6057
type: UnificationXref
id: 6057
db: PubChem-compound

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/HMDB HMDB0012283
type: UnificationXref
id: HMDB0012283
db: HMDB

Reference/KEGG Compound C01179
type: UnificationXref
id: C01179
db: KEGG Compound

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/CAS 156-39-8
type: UnificationXref
id: 156-39-8
db: CAS

Reference/TAXONOMY 4932
type: UnificationXref
id: 4932
db: TAXONOMY

aromatic amino acid aminotransferase II
type: Protein
entity reference: aromatic amino acid aminotransferase II

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

ChemicalStructure/PW C007823
type: ChemicalStructure
structure format: SMILES

Reference/UniProt Q04894
type: UnificationXref
id: Q04894
db: UniProt

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/ChEBI CHEBI 17895
type: UnificationXref
id: CHEBI:17895
db: ChEBI

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/UniProt P06169
type: UnificationXref
id: P06169
db: UniProt

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

L-Alanine
type: SmallMolecule
entity reference: L-Alanine

ChemicalStructure/PW C001966
type: ChemicalStructure
structure format: SMILES
structure data: OC1=CC=C(CC=O)C=C1

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

L-Tyrosine
type: SmallMolecule
entity reference: L-Tyrosine

Reference/PubChem-compound 12039
type: UnificationXref
id: 12039
db: PubChem-compound

Reference/ChemSpider 389113
type: UnificationXref
id: 389113
db: ChemSpider

Reference/PubChem-compound 440113
type: UnificationXref
id: 440113
db: PubChem-compound

alcohol dehydrogenase
type: Complex
component: alcohol dehydrogenase subunit I
component: alcohol dehydrogenase subunit 2

Reference/PubChem-compound 979
type: UnificationXref
id: 979
db: PubChem-compound

Reference/CAS 501-94-0
type: UnificationXref
id: 501-94-0
db: CAS