Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/TAXONOMY 3702
type: UnificationXref
id: 3702
db: TAXONOMY

Oxidized ferredoxin
type: ProteinReference

Reduced ferredoxin
type: ProteinReference

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Succinic acid semialdehyde
type: SmallMolecule
entity reference: Succinic acid semialdehyde

Succinic acid
type: SmallMolecule
entity reference: Succinic acid

NADH
type: SmallMolecule
entity reference: NADH

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/UniProt Q9ZPS3
type: UnificationXref
id: Q9ZPS3
db: UniProt

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Reference/UniProt Q9ZPS4
type: UnificationXref
id: Q9ZPS4
db: UniProt

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/UniProt Q9SAK4
type: UnificationXref
id: Q9SAK4
db: UniProt

Hydrogen Ion
type: SmallMolecule
cellular location: Chloroplast
entity reference: Hydrogen Ion

Reference/PubChem-compound 119
type: UnificationXref
id: 119
db: PubChem-compound

NAD
type: SmallMolecule
entity reference: NAD

Glutamate dehydrogenase 1
type: Protein
entity reference: Glutamate dehydrogenase 1

Reference/PubChem-compound 5961
type: UnificationXref
id: 5961
db: PubChem-compound

Compound/PW C000095 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Reference/ChEBI CHEBI 16265
type: UnificationXref
id: CHEBI:16265
db: ChEBI

Compound/PW C040034 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Glutamate dehydrogenase 2
type: Protein
entity reference: Glutamate dehydrogenase 2

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Oxidized ferredoxin
type: Protein
cellular location: Chloroplast
entity reference: Oxidized ferredoxin

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reduced ferredoxin
type: Protein
cellular location: Chloroplast
entity reference: Reduced ferredoxin

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/CAS 591-81-1
type: UnificationXref
id: 591-81-1
db: CAS

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/ChemSpider 5746
type: UnificationXref
id: 5746
db: ChemSpider

Reference/BioCyc CPD-3193
type: UnificationXref
id: CPD-3193
db: BioCyc

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/KEGG Compound C00334
type: UnificationXref
id: C00334
db: KEGG Compound

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/GENE ONTOLOGY GO 0009507
type: UnificationXref
id: GO:0009507
db: GENE ONTOLOGY

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/ChemSpider 5735
type: UnificationXref
id: 5735
db: ChemSpider

Compound/PW C000561/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-Hydroxybutyric acid
stoichiometric coefficient: 1.0

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C000561
type: ChemicalStructure
structure format: SMILES
structure data: OCCCC(O)=O

NADP
type: SmallMolecule
entity reference: NADP

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

ReactionCatalysis7184
type: Catalysis
controller: Succinate-semialdehyde dehydrogenase, mitochondrial
controlled: 1.2.1.24
control type: ACTIVATION

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

ReactionCatalysis7183
type: Catalysis
controller: Gamma-aminobutyrate transaminase POP2, mitochondrial
controlled: Reaction7197
control type: ACTIVATION

Glutamate dehydrogenase 1
type: ProteinReference
xref: Reference/UniProt Q43314

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

ReactionCatalysis7182
type: Catalysis
controller: Gamma-aminobutyrate transaminase POP2, mitochondrial
controlled: 2.6.1.96
control type: ACTIVATION

Ammonium
type: SmallMolecule
entity reference: Ammonium

ReactionCatalysis7181
type: Catalysis
controller: Glutamate decarboxylase
controlled: 4.1.1.15
control type: ACTIVATION

Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial
type: Protein
cellular location: Chloroplast
entity reference: Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial

L-Glutamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000641
xref: Reference/ChEBI CHEBI 18050
xref: Reference/ChemSpider 5746
xref: Reference/BioCyc GLN
xref: Reference/KEGG Compound C00064
xref: Reference/PubChem-compound 5961
xref: Reference/CAS 56-85-9
chemical formula: C5H10N2O3
molecular weight: 146.06914
structure: ChemicalStructure/PW C000500

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 16977
type: UnificationXref
id: CHEBI:16977
db: ChEBI

ReactionCatalysis7185
type: Catalysis
controller: Glyoxylate/succinic semialdehyde reductase 1
controlled: 1.1.1.79,1.1.1.n11
control type: ACTIVATION

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Reference/KEGG Compound C00232
type: UnificationXref
id: C00232
db: KEGG Compound

Reference/UniProt Q94CE5
type: UnificationXref
id: Q94CE5
db: UniProt

ReactionCatalysis7180
type: Catalysis
controller: Probable glutamate dehydrogenase 3
controlled: 1.4.1.3
control type: ACTIVATION

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Reference/BioCyc SUC
type: UnificationXref
id: SUC
db: BioCyc

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

γ-Aminobutyric acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000112
xref: Reference/ChemSpider 116
xref: Reference/PubChem-compound 119
xref: Reference/CAS 56-12-2
xref: Reference/BioCyc 4-AMINO-BUTYRATE
xref: Reference/ChEBI CHEBI 16865
xref: Reference/KEGG Compound C00334
chemical formula: C4H9NO2
molecular weight: 103.06333
structure: ChemicalStructure/PW C000071

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Reference/CAS 692-29-5
type: UnificationXref
id: 692-29-5
db: CAS

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Protein/Generic211 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxidized ferredoxin
stoichiometric coefficient: 1.0

Oxidized ferredoxin
type: Protein
entity reference: Oxidized ferredoxin

Reduced ferredoxin
type: Protein
entity reference: Reduced ferredoxin

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Compound/PW C000500/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16865
type: UnificationXref
id: CHEBI:16865
db: ChEBI

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Glutamate dehydrogenase 2
type: ProteinReference
xref: Reference/UniProt Q38946

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/BioCyc L-ALPHA-ALANINE
type: UnificationXref
id: L-ALPHA-ALANINE
db: BioCyc

Succinate-semialdehyde dehydrogenase, mitochondrial
type: Protein
entity reference: Succinate-semialdehyde dehydrogenase, mitochondrial

Glyoxylate/succinic semialdehyde reductase 1
type: Protein
entity reference: Glyoxylate/succinic semialdehyde reductase 1

Reference/CAS 56-41-7
type: UnificationXref
id: 56-41-7
db: CAS

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Glutamate decarboxylase 3
type: Protein
entity reference: Glutamate decarboxylase 3

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Glutamate decarboxylase 4
type: Protein
entity reference: Glutamate decarboxylase 4

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Glutamate decarboxylase 5
type: Protein
entity reference: Glutamate decarboxylase 5

Gamma-aminobutyrate transaminase POP2, mitochondrial
type: Protein
entity reference: Gamma-aminobutyrate transaminase POP2, mitochondrial

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

Glutamate dehydrogenase
type: Complex
component: Glutamate dehydrogenase 2
component: Glutamate dehydrogenase 1

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Glutamic Acid Metabolism
type: Pathway
pathway order: PathwayTransport/2123673
pathway order: PathwayEnzymeReaction/26570
pathway order: PathwayEnzymeReaction/26571
pathway order: PathwayEnzymeReaction/2123674
pathway order: PathwayEnzymeReaction/26572
pathway order: PathwayEnzymeReaction/26573
pathway order: PathwayEnzymeReaction/26574
pathway order: PathwayEnzymeReaction/26575
pathway order: PathwayEnzymeReaction/26576
pathway order: PathwayEnzymeReaction/26577
pathway order: PathwayEnzymeReaction/26569
pathway component: ReactionCatalysis7184
pathway component: ReactionCatalysis7183
pathway component: Reaction7193
pathway component: ReactionCatalysis7182
pathway component: 1.4.1.14
pathway component: ReactionCatalysis7181
pathway component: 4.1.1.15
pathway component: 1.4.1.3
pathway component: ReactionCatalysis7175
pathway component: Reaction7197
pathway component: 2.6.1.96
pathway component: ReactionCatalysis7185
pathway component: ReactionCatalysis7180
pathway component: Transport10333
pathway component: 1.1.1.79,1.1.1.n11
pathway component: 1.2.1.24
pathway component: ReactionCatalysis7179
pathway component: ReactionCatalysis7178
pathway component: 1.4.7.1
xref: Reference/PathWhiz PW002534
xref: Reference/SMPDB SMP0002427
organism: Arabidopsis thaliana

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005759
type: UnificationXref
id: GO:0005759
db: GENE ONTOLOGY

Reference/BioCyc GLN
type: UnificationXref
id: GLN
db: BioCyc

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Reference/ChEBI CHEBI 15741
type: UnificationXref
id: CHEBI:15741
db: ChEBI

Probable glutamate dehydrogenase 3
type: Protein
entity reference: Probable glutamate dehydrogenase 3

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Glutamate decarboxylase 1
type: Protein
entity reference: Glutamate decarboxylase 1

Glutamate decarboxylase 2
type: Protein
entity reference: Glutamate decarboxylase 2

Reference/PubChem-compound 1112
type: UnificationXref
id: 1112
db: PubChem-compound

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

ChemicalStructure/PW C000105
type: ChemicalStructure
structure format: SMILES
structure data: C[C@H](N)C(O)=O

Glutamate synthase 1 [NADH], chloroplastic
type: Protein
entity reference: Glutamate synthase 1 [NADH], chloroplastic

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/PubChem-compound 5950
type: UnificationXref
id: 5950
db: PubChem-compound

Reference/PubChem-compound 1110
type: UnificationXref
id: 1110
db: PubChem-compound

Reference/HMDB HMDB0000112
type: UnificationXref
id: HMDB0000112
db: HMDB

Reference/ChemSpider 116
type: UnificationXref
id: 116
db: ChemSpider

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

γ-Aminobutyric acid
type: SmallMolecule
entity reference: γ-Aminobutyric acid

Succinic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000254
xref: Reference/CAS 110-15-6
xref: Reference/ChEBI CHEBI 15741
xref: Reference/KEGG Compound C00042
xref: Reference/ChemSpider 1078
xref: Reference/PubChem-compound 1110
xref: Reference/BioCyc SUC
chemical formula: C4H6O4
molecular weight: 118.02661
structure: ChemicalStructure/PW C000174

Compound/PW C000134 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/UniProt Q9S7A0
type: UnificationXref
id: Q9S7A0
db: UniProt

Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial
type: Protein
entity reference: Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial

Succinic acid semialdehyde
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001259
xref: Reference/BioCyc SUCC-S-ALD
xref: Reference/ChemSpider 1080
xref: Reference/CAS 692-29-5
xref: Reference/KEGG Compound C00232
xref: Reference/PubChem-compound 1112
xref: Reference/ChEBI CHEBI 16265
chemical formula: C4H6O3
molecular weight: 102.03169
structure: ChemicalStructure/PW C000972

L-Glutamine
type: SmallMolecule
entity reference: L-Glutamine

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Protein/Generic211/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxidized ferredoxin
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Transport10333
type: Transport
participant stoichiometry: Compound/PW C000095 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Chloroplast/Stoichiometry/1.0
right: L-Glutamic acid
spontaneous: false
left: L-Glutamic acid
name: L-Glutamic acid (?) Transport: Arabidopsis thaliana, Cell, Chloroplast to Arabidopsis thaliana, Cell, Mitochondrial Matrix
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Reference/UniProt Q9ZNZ7
type: UnificationXref
id: Q9ZNZ7
db: UniProt

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

L-Glutamic acid
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: L-Glutamic acid

Succinate-semialdehyde dehydrogenase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q9SAK4

Gamma-aminobutyrate transaminase POP2, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q94CE5

Glyoxylate/succinic semialdehyde reductase 1
type: ProteinReference
xref: Reference/UniProt Q9LSV0

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Glutamate decarboxylase 3
type: ProteinReference
xref: Reference/UniProt Q9ZPS4

Reference/SMPDB SMP0002427
type: UnificationXref
id: SMP0002427
db: SMPDB

Reference/BioCyc SUCC-S-ALD
type: UnificationXref
id: SUCC-S-ALD
db: BioCyc

Glutamate decarboxylase 5
type: ProteinReference
xref: Reference/UniProt Q9LSH2

Glutamate decarboxylase 4
type: ProteinReference
xref: Reference/UniProt Q9ZPS3

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

L-Glutamic acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Glutamic acid

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000254
type: UnificationXref
id: HMDB0000254
db: HMDB

Reference/ChEBI CHEBI 30830
type: UnificationXref
id: CHEBI:30830
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C000174
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(O)=O

Glutamate decarboxylase
type: Complex
component: Glutamate decarboxylase 1
component: Glutamate decarboxylase 2
component: Glutamate decarboxylase 3
component: Glutamate decarboxylase 4
component: Glutamate decarboxylase 5

ChemicalStructure/PW C000972
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC=O

Reference/KEGG Compound C00041
type: UnificationXref
id: C00041
db: KEGG Compound

1.1.1.79,1.1.1.n11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000972/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000561/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADP
right: 4-Hydroxybutyric acid
spontaneous: false
EC number: 1.1.1.79,1.1.1.n11
left: Hydrogen Ion
left: Succinic acid semialdehyde
left: NADPH
name: Hydrogen Ion + NADPH + Succinic acid semialdehyde → 4-Hydroxybutyric acid + NADP
conversion direction: LEFT_TO_RIGHT

1.2.1.24
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000972/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Succinic acid
right: NADH
right: Hydrogen Ion
spontaneous: false
EC number: 1.2.1.24
left: Water
left: NAD
left: Succinic acid semialdehyde
name: NAD + Succinic acid semialdehyde + Water → Hydrogen Ion + NADH + Succinic acid
conversion direction: LEFT_TO_RIGHT

Mitochondrial Matrix
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005759

Reaction7193
type: BiochemicalReaction
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: L-Glutamic acid
right: Water
right: NADP
spontaneous: false
left: Ammonium
left: Oxoglutaric acid
left: NADPH
name: Ammonium + NADPH + Oxoglutaric acid ↔ L-Glutamic acid + NADP + Water
conversion direction: REVERSIBLE

1.4.1.14
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: L-Glutamic acid
right: NAD
spontaneous: false
EC number: 1.4.1.14
left: NADH
left: Oxoglutaric acid
left: Hydrogen Ion
left: L-Glutamine
name: Hydrogen Ion + L-Glutamine + NADH + Oxoglutaric acid → L-Glutamic acid + NAD
conversion direction: LEFT_TO_RIGHT

4.1.1.15
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000071/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Carbon dioxide
right: γ-Aminobutyric acid
spontaneous: false
EC number: 4.1.1.15
left: L-Glutamic acid
left: Hydrogen Ion
name: Hydrogen Ion + L-Glutamic acid → Carbon dioxide + γ-Aminobutyric acid
conversion direction: LEFT_TO_RIGHT

1.4.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: Water
right: L-Glutamic acid
right: NADP
spontaneous: false
EC number: 1.4.1.3
left: Ammonium
left: Oxoglutaric acid
left: NADPH
name: Ammonium + NADPH + Oxoglutaric acid ↔ L-Glutamic acid + NADP + Water
conversion direction: REVERSIBLE

Reaction7197
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000105/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000972/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000071/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
right: L-Alanine
right: Succinic acid semialdehyde
spontaneous: false
left: Pyruvic acid
left: γ-Aminobutyric acid
name: Pyruvic acid + γ-Aminobutyric acid → L-Alanine + Succinic acid semialdehyde
conversion direction: LEFT_TO_RIGHT

2.6.1.96
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000972/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000071/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: L-Glutamic acid
right: Succinic acid semialdehyde
spontaneous: false
EC number: 2.6.1.96
left: Oxoglutaric acid
left: γ-Aminobutyric acid
name: Oxoglutaric acid + γ-Aminobutyric acid → L-Glutamic acid + Succinic acid semialdehyde
conversion direction: LEFT_TO_RIGHT

Reference/UniProt Q9LV03
type: UnificationXref
id: Q9LV03
db: UniProt

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/KEGG Compound C00042
type: UnificationXref
id: C00042
db: KEGG Compound

Reference/ChemSpider 1078
type: UnificationXref
id: 1078
db: ChemSpider

Reference/CAS 56-85-9
type: UnificationXref
id: 56-85-9
db: CAS

Compound/PW C000500 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Protein/Generic212 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Reduced ferredoxin
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Reference/ChemSpider 1080
type: UnificationXref
id: 1080
db: ChemSpider

4-Hydroxybutyric acid
type: SmallMolecule
entity reference: 4-Hydroxybutyric acid

1.4.7.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Protein/Generic212 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500/Stoichiometry/1.0
participant stoichiometry: Protein/Generic211 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Protein/Generic211/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Protein/Generic212/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500 Chloroplast/Stoichiometry/1.0
right: Oxidized ferredoxin
right: L-Glutamic acid
spontaneous: false
EC number: 1.4.7.1
left: Hydrogen Ion
left: Reduced ferredoxin
left: Oxoglutaric acid
left: L-Glutamine
name: Hydrogen Ion + L-Glutamine + Oxoglutaric acid + Reduced ferredoxin → L-Glutamic acid + Oxidized ferredoxin
conversion direction: LEFT_TO_RIGHT

4-Hydroxybutyric acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 30830
xref: Reference/HMDB HMDB0000710
xref: Reference/KEGG Compound C00989
xref: Reference/BioCyc CPD-3193
xref: Reference/PubChem-compound 10413
xref: Reference/CAS 591-81-1
xref: Reference/ChemSpider 9984
chemical formula: C4H8O3
molecular weight: 104.04734
structure: ChemicalStructure/PW C000561

Oxoglutaric acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: Oxoglutaric acid

L-Glutamine
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Glutamine

Arabidopsis thaliana
type: BioSource
xref: Reference/TAXONOMY 3702

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/UniProt Q9LSH2
type: UnificationXref
id: Q9LSH2
db: UniProt

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Reference/HMDB HMDB0000710
type: UnificationXref
id: HMDB0000710
db: HMDB

Compound/PW C000095 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Reference/UniProt Q42521
type: UnificationXref
id: Q42521
db: UniProt

Compound/PW C000972/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid semialdehyde
stoichiometric coefficient: 1.0

ReactionCatalysis7175
type: Catalysis
controller: Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial
controlled: 1.4.7.1
control type: ACTIVATION

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/KEGG Compound C00989
type: UnificationXref
id: C00989
db: KEGG Compound

Reference/KEGG Compound C00064
type: UnificationXref
id: C00064
db: KEGG Compound

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/HMDB HMDB0001259
type: UnificationXref
id: HMDB0001259
db: HMDB

Reference/UniProt Q38946
type: UnificationXref
id: Q38946
db: UniProt

ReactionCatalysis7179
type: Catalysis
controller: Glutamate dehydrogenase
controlled: Reaction7193
control type: ACTIVATION

Reference/HMDB HMDB0000161
type: UnificationXref
id: HMDB0000161
db: HMDB

ReactionCatalysis7178
type: Catalysis
controller: Glutamate synthase 1 [NADH], chloroplastic
controlled: 1.4.1.14
control type: ACTIVATION

Protein/Generic212/Stoichiometry/1.0
type: Stoichiometry
physical entity: Reduced ferredoxin
stoichiometric coefficient: 1.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

L-Alanine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00041
xref: Reference/ChemSpider 5735
xref: Reference/ChEBI CHEBI 16977
xref: Reference/BioCyc L-ALPHA-ALANINE
xref: Reference/HMDB HMDB0000161
xref: Reference/CAS 56-41-7
xref: Reference/PubChem-compound 5950
chemical formula: C3H7NO2
molecular weight: 89.047676
structure: ChemicalStructure/PW C000105

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Compound/PW C000174/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/CAS 110-15-6
type: UnificationXref
id: 110-15-6
db: CAS

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

Compound/PW C000105/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Alanine
stoichiometric coefficient: 1.0

Reference/UniProt Q42472
type: UnificationXref
id: Q42472
db: UniProt

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/UniProt Q43314
type: UnificationXref
id: Q43314
db: UniProt

Chloroplast
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0009507

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Compound/PW C022608/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/CAS 56-12-2
type: UnificationXref
id: 56-12-2
db: CAS

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

ChemicalStructure/PW C000500
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(N)=O)C(O)=O

Reference/ChemSpider 9984
type: UnificationXref
id: 9984
db: ChemSpider

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/ChEBI CHEBI 18050
type: UnificationXref
id: CHEBI:18050
db: ChEBI

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc 4-AMINO-BUTYRATE
type: UnificationXref
id: 4-AMINO-BUTYRATE
db: BioCyc

Ferredoxin-dependent glutamate synthase 1, chloroplastic/mitochondrial
type: ProteinReference
xref: Reference/UniProt Q9ZNZ7

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

ChemicalStructure/PW C000071
type: ChemicalStructure
structure format: SMILES
structure data: NCCCC(O)=O

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/PathWhiz PW002534
type: UnificationXref
id: PW002534
db: PathWhiz

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Compound/PW C000071/Stoichiometry/1.0
type: Stoichiometry
physical entity: γ-Aminobutyric acid
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

L-Alanine
type: SmallMolecule
entity reference: L-Alanine

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/PubChem-compound 10413
type: UnificationXref
id: 10413
db: PubChem-compound

Reference/HMDB HMDB0000641
type: UnificationXref
id: HMDB0000641
db: HMDB

Probable glutamate dehydrogenase 3
type: ProteinReference
xref: Reference/UniProt Q9S7A0

Glutamate synthase 1 [NADH], chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9LV03

Glutamate decarboxylase 2
type: ProteinReference
xref: Reference/UniProt Q42472

Reference/UniProt Q9LSV0
type: UnificationXref
id: Q9LSV0
db: UniProt

Glutamate decarboxylase 1
type: ProteinReference
xref: Reference/UniProt Q42521