Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/ChEBI CHEBI 15961
type: UnificationXref
id: CHEBI:15961
db: ChEBI

Reference/BioCyc O-PHOSPHO-L-HOMOSERINE
type: UnificationXref
id: O-PHOSPHO-L-HOMOSERINE
db: BioCyc

Reference/TAXONOMY 3702
type: UnificationXref
id: 3702
db: TAXONOMY

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Oxalacetic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000223
xref: Reference/CAS 328-42-7
xref: Reference/ChEBI CHEBI 30744
xref: Reference/BioCyc OXALACETIC ACID
xref: Reference/ChemSpider 945
xref: Reference/PubChem-compound 970
xref: Reference/KEGG Compound C00036
chemical formula: C4H4O5
molecular weight: 132.00587
structure: ChemicalStructure/PW C000148

Compound/PW C007795 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartyl-4-phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/CAS 22138-53-0
type: UnificationXref
id: 22138-53-0
db: CAS

NADH
type: SmallMolecule
entity reference: NADH

NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
type: Protein
entity reference: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase

ChemicalStructure/PW C000570
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCO)C(O)=O

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

L-Aspartate-semialdehyde
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Aspartate-semialdehyde

Reference/ChemSpider 57
type: UnificationXref
id: 57
db: ChemSpider

Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
type: Protein
entity reference: Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003484
type: UnificationXref
id: HMDB0003484
db: HMDB

Protein/10609 Chloroplast/Stoichiometry/2.0
type: Stoichiometry
physical entity: Aspartokinase
stoichiometric coefficient: 2.0

Hydrogen Ion
type: SmallMolecule
cellular location: Chloroplast
entity reference: Hydrogen Ion

Reference/UniProt Q8RXU4
type: UnificationXref
id: Q8RXU4
db: UniProt

Reference/ChemSpider 809
type: UnificationXref
id: 809
db: ChemSpider

Compound/PW C040940 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-iminobutanoate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00441
type: UnificationXref
id: C00441
db: KEGG Compound

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

NAD
type: SmallMolecule
entity reference: NAD

Reference/BioCyc OXALACETIC ACID
type: UnificationXref
id: OXALACETIC_ACID
db: BioCyc

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C000095 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Compound/PW C040034 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Phosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Phosphate

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Compound/PW C001905/Stoichiometry/1.0
type: Stoichiometry
physical entity: O-Phosphohomoserine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/CAS 328-42-7
type: UnificationXref
id: 328-42-7
db: CAS

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

2.7.2.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000123 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007795 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Chloroplast/Stoichiometry/1.0
right: L-Aspartyl-4-phosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.2.4
left: Adenosine triphosphate
left: L-Aspartic acid
name: Adenosine triphosphate + L-Aspartic acid → Adenosine diphosphate + L-Aspartyl-4-phosphate
conversion direction: LEFT_TO_RIGHT

4.3.1.19
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000109 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040939 Chloroplast/Stoichiometry/1.0
right: Hydrogen Ion
right: Water
right: (2Z)-2-aminobut-2-enoate
spontaneous: false
EC number: 4.3.1.19
left: L-Threonine
name: L-Threonine → (2Z)-2-aminobut-2-enoate + Hydrogen Ion + Water
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/PubChem-compound 19796801
type: UnificationXref
id: 19796801
db: PubChem-compound

Reference/PubChem-compound 58
type: UnificationXref
id: 58
db: PubChem-compound

Reference/PubChem-compound 6288
type: UnificationXref
id: 6288
db: PubChem-compound

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reaction2924
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040940 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C022608 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000003 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: 2-Ketobutyric acid
right: Ammonium
spontaneous: true
left: Hydrogen Ion
left: Water
left: 2-iminobutanoate
name: 2-iminobutanoate + Hydrogen Ion + Water → 2-Ketobutyric acid + Ammonium
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 5745
type: UnificationXref
id: 5745
db: ChemSpider

Reference/BioCyc THR
type: UnificationXref
id: THR
db: BioCyc

Compound/PW C000940/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/BioCyc L-ASPARTATE
type: UnificationXref
id: L-ASPARTATE
db: BioCyc

Compound/PW C000414 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Acetaldehyde
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Acetaldehyde

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

ReactionCatalysis7209
type: Catalysis
controller: threonine deaminase
controlled: 4.3.1.19
control type: ACTIVATION

Reference/GENE ONTOLOGY GO 0009507
type: UnificationXref
id: GO:0009507
db: GENE ONTOLOGY

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Reaction2923
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040940 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040939 Chloroplast/Stoichiometry/1.0
right: 2-iminobutanoate
spontaneous: true
left: (2Z)-2-aminobut-2-enoate
name: (2Z)-2-aminobut-2-enoate → 2-iminobutanoate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

O-Phosphohomoserine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 151187
xref: Reference/CAS 4210-66-6
xref: Reference/ChEBI CHEBI 15961
xref: Reference/BioCyc O-PHOSPHO-L-HOMOSERINE
xref: Reference/ChemSpider 133252
xref: Reference/HMDB HMDB0003484
xref: Reference/KEGG Compound C01102
chemical formula: C4H10NO6P
molecular weight: 199.02457
structure: ChemicalStructure/PW C001905

Reference/KEGG Compound C00109
type: UnificationXref
id: C00109
db: KEGG Compound

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA

L-Aspartyl-4-phosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Aspartyl-4-phosphate

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChemSpider 945
type: UnificationXref
id: 945
db: ChemSpider

Reference/UniProt P10869
type: UnificationXref
id: P10869
db: UniProt

ChemicalStructure/PW C040939
type: ChemicalStructure
structure format: SMILES
structure data: CC=C(N)C([O-])=O

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/UniProt Q8S7B5
type: UnificationXref
id: Q8S7B5
db: UniProt

NADP
type: SmallMolecule
entity reference: NADP

Reference/CAS 600-18-0
type: UnificationXref
id: 600-18-0
db: CAS

Compound/PW C022608 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Mitochondrion
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005739

Aspartate semialdehyde dehydrogenase
type: ProteinReference
xref: Reference/UniProt Q8VYI4

Compound/PW C000784 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetaldehyde
stoichiometric coefficient: 1.0

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/BioCyc GLY
type: UnificationXref
id: GLY
db: BioCyc

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 16857
type: UnificationXref
id: CHEBI:16857
db: ChEBI

Compound/PW C001034 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Reference/CAS 672-15-1
type: UnificationXref
id: 672-15-1
db: CAS

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Probable low-specificity L-threonine aldolase 1
type: Protein
entity reference: Probable low-specificity L-threonine aldolase 1

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

L-Homoserine
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Homoserine

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/CAS 72-19-5
type: UnificationXref
id: 72-19-5
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Reference/CAS 4210-66-6
type: UnificationXref
id: 4210-66-6
db: CAS

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

L-Threonine
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Threonine

Glycine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000123
xref: Reference/BioCyc GLY
xref: Reference/ChemSpider 730
xref: Reference/PubChem-compound 5257127
xref: Reference/CAS 56-40-6
xref: Reference/ChEBI CHEBI 15428
xref: Reference/KEGG Compound C00037
chemical formula: C2H5NO2
molecular weight: 75.03203
structure: ChemicalStructure/PW C000078

Reference/UniProt Q8L7R2
type: UnificationXref
id: Q8L7R2
db: UniProt

(2Z)-2-aminobut-2-enoate
type: SmallMolecule
cellular location: Chloroplast
entity reference: (2Z)-2-aminobut-2-enoate

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

ReactionCatalysis7194
type: Catalysis
controller: Probable low-specificity L-threonine aldolase 1
controlled: 4.1.2.48
control type: ACTIVATION

Reference/UniProt Q8VYI4
type: UnificationXref
id: Q8VYI4
db: UniProt

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

ChemicalStructure/PW C001905
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCOP(O)(O)=O)C(O)=O

Aspartokinase 2, chloroplastic
type: ProteinReference
xref: Reference/UniProt O23653
organism: Arabidopsis thaliana

Reaction7271
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007795/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007794/Stoichiometry/1.0
right: NADP
right: L-Aspartate-semialdehyde
right: Phosphate
spontaneous: false
left: Hydrogen Ion
left: L-Aspartyl-4-phosphate
left: NADPH
name: Hydrogen Ion + L-Aspartyl-4-phosphate + NADPH → L-Aspartate-semialdehyde + NADP + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt Q0WM29
type: UnificationXref
id: Q0WM29
db: UniProt

Aspartokinase 1, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9LYU8
organism: Arabidopsis thaliana

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

NADP
type: SmallMolecule
cellular location: Chloroplast
entity reference: NADP

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

threonine deaminase
type: Complex
component stoichiometry: Protein/11158 Chloroplast/Stoichiometry/4.0
cellular location: Chloroplast
component: Threonine dehydratase biosynthetic, chloroplastic

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/BioCyc 2-OXOBUTANOATE
type: UnificationXref
id: 2-OXOBUTANOATE
db: BioCyc

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

(2Z)-2-aminobut-2-enoate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58739
chemical formula: C4H6NO2
molecular weight: 100.040405
structure: ChemicalStructure/PW C040939

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Compound/PW C007794 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartate-semialdehyde
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Compound/PW C000109 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Threonine
stoichiometric coefficient: 1.0

Reference/ChemSpider 6051
type: UnificationXref
id: 6051
db: ChemSpider

Reference/PubChem-compound 5257127
type: UnificationXref
id: 5257127
db: PubChem-compound

Reference/HMDB HMDB0000223
type: UnificationXref
id: HMDB0000223
db: HMDB

Reference/KEGG Compound C03082
type: UnificationXref
id: C03082
db: KEGG Compound

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis6301
type: Catalysis
controller: Aspartate kinase
controlled: 2.7.2.4
control type: ACTIVATION

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

2-Ketobutyric acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: 2-Ketobutyric acid

Reference/UniProt Q9ZSS6
type: UnificationXref
id: Q9ZSS6
db: UniProt

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

2-iminobutanoate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 19796801
chemical formula: C4H6NO2
molecular weight: 100.040405
structure: ChemicalStructure/PW C040940

Reference/PubChem-compound 44367445
type: UnificationXref
id: 44367445
db: PubChem-compound

Compound/PW C000784/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetaldehyde
stoichiometric coefficient: 1.0

Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
type: ProteinReference
xref: Reference/UniProt Q0WM29

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
type: ProteinReference
xref: Reference/UniProt Q1WIQ6

ChemicalStructure/PW C000109
type: ChemicalStructure
structure format: SMILES
structure data: C[C@@H](O)[C@H](N)C(O)=O

Reference/KEGG Compound C01102
type: UnificationXref
id: C01102
db: KEGG Compound

Compound/PW C000570/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Homoserine
stoichiometric coefficient: 1.0

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Glycine
type: SmallMolecule
entity reference: Glycine

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

2.6.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000123 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000148 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134 Chloroplast/Stoichiometry/1.0
right: L-Aspartic acid
right: Oxoglutaric acid
spontaneous: false
EC number: 2.6.1.1
left: Oxalacetic acid
left: L-Glutamic acid
name: L-Glutamic acid + Oxalacetic acid ↔ L-Aspartic acid + Oxoglutaric acid
conversion direction: REVERSIBLE

Compound/PW C000134 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 12126
type: UnificationXref
id: 12126
db: ChemSpider

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Ammonium
type: SmallMolecule
cellular location: Chloroplast
entity reference: Ammonium

2.7.1.39
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000570/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001905/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: O-Phosphohomoserine
spontaneous: false
EC number: 2.7.1.39
left: L-Homoserine
left: Adenosine triphosphate
name: Adenosine triphosphate + L-Homoserine → Adenosine diphosphate + Hydrogen Ion + O-Phosphohomoserine
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00263
type: UnificationXref
id: C00263
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Compound/PW C007794/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartate-semialdehyde
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Threonine Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/27209
pathway order: PathwayTransport/27214
pathway order: PathwayEnzymeReaction/27213
pathway order: PathwayEnzymeReaction/27212
pathway order: PathwayEnzymeReaction/27217
pathway order: PathwayEnzymeReaction/27216
pathway order: PathwayEnzymeReaction/27219
pathway order: PathwayEnzymeReaction/27207
pathway order: PathwayEnzymeReaction/27218
pathway order: PathwayEnzymeReaction/27220
pathway order: PathwayEnzymeReaction/27211
pathway order: PathwayEnzymeReaction/27222
pathway order: PathwayEnzymeReaction/27221
pathway component: ReactionCatalysis7194
pathway component: ReactionCatalysis7293
pathway component: ReactionCatalysis7292
pathway component: ReactionCatalysis7291
pathway component: Reaction7271
pathway component: 2.7.1.39
pathway component: ReactionCatalysis7165
pathway component: ReactionCatalysis7252
pathway component: Reaction2924
pathway component: Transport580
pathway component: ReactionCatalysis7290
pathway component: 4.2.3.1
pathway component: ReactionCatalysis7209
pathway component: 4.1.2.48
pathway component: 2.7.2.4
pathway component: 1.2.1.4
pathway component: ReactionCatalysis6301
pathway component: Reaction2923
pathway component: 2.6.1.1
pathway component: 4.3.1.19
pathway component: ReactionCatalysis7266
pathway component: Reaction7321
xref: Reference/PathWhiz PW002554
xref: Reference/SMPDB SMP0002444
organism: Arabidopsis thaliana

Reference/HMDB HMDB0000123
type: UnificationXref
id: HMDB0000123
db: HMDB

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Reference/GENE ONTOLOGY GO 0005739
type: UnificationXref
id: GO:0005739
db: GENE ONTOLOGY

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Water
type: SmallMolecule
cellular location: Chloroplast
entity reference: Water

Reference/HMDB HMDB0000005
type: UnificationXref
id: HMDB0000005
db: HMDB

ChemicalStructure/PW C000003
type: ChemicalStructure
structure format: SMILES
structure data: CCC(=O)C(O)=O

Aspartokinase
type: Protein
cellular location: Chloroplast
entity reference: Aspartokinase

ChemicalStructure/PW C000123
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC(O)=O)C(O)=O

Protein/11185 Chloroplast/Stoichiometry/4.0
type: Stoichiometry
physical entity: Aspartokinase 2, chloroplastic
stoichiometric coefficient: 4.0

ChemicalStructure/PW C007794
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC=O)C(O)=O

ChemicalStructure/PW C007795
type: ChemicalStructure
structure format: SMILES
structure data: NC(CC(=O)OP(O)(O)=O)C(O)=O

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Compound/PW C000078/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycine
stoichiometric coefficient: 1.0

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Compound/PW C000146 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Compound/PW C000143 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Homoserine kinase
type: Protein
entity reference: Homoserine kinase

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Compound/PW C000784 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetaldehyde
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00037
type: UnificationXref
id: C00037
db: KEGG Compound

Reference/KEGG Compound C00036
type: UnificationXref
id: C00036
db: KEGG Compound

L-Glutamic acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Glutamic acid

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

L-Homoserine
type: SmallMolecule
entity reference: L-Homoserine

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Reference/ChEBI CHEBI 30831
type: UnificationXref
id: CHEBI:30831
db: ChEBI

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Aspartokinase
type: ProteinReference
xref: Reference/UniProt P10869
organism: Arabidopsis thaliana

ReactionCatalysis7266
type: Catalysis
controller: Homoserine kinase
controlled: 2.7.1.39
control type: ACTIVATION

O-Phosphohomoserine
type: SmallMolecule
cellular location: Chloroplast
entity reference: O-Phosphohomoserine

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Protein/11184 Chloroplast/Stoichiometry/2.0
type: Stoichiometry
physical entity: Aspartokinase 1, chloroplastic
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0012249
type: UnificationXref
id: HMDB0012249
db: HMDB

Reference/ChEBI CHEBI 15699
type: UnificationXref
id: CHEBI:15699
db: ChEBI

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Threonine synthase 1, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q8S7B5
organism: Arabidopsis thaliana

Probable low-specificity L-threonine aldolase 1
type: ProteinReference
xref: Reference/UniProt Q8RXU4

aspartate kinase / homoserine dehydrogenase
type: Complex
component stoichiometry: Protein/11184 Chloroplast/Stoichiometry/2.0
component stoichiometry: Protein/11185 Chloroplast/Stoichiometry/4.0
cellular location: Chloroplast
component: Aspartokinase 1, chloroplastic
component: Aspartokinase 2, chloroplastic

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Aspartokinase 1, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Aspartokinase 1, chloroplastic

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Reference/KEGG Compound C00049
type: UnificationXref
id: C00049
db: KEGG Compound

Aspartokinase 2, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Aspartokinase 2, chloroplastic

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Compound/PW C001420 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Reference/UniProt P46644
type: UnificationXref
id: P46644
db: UniProt

Reference/ChEBI CHEBI 58739
type: UnificationXref
id: CHEBI:58739
db: ChEBI

L-Aspartic acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Aspartic acid

Oxoglutaric acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: Oxoglutaric acid

Threonine dehydratase biosynthetic, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9ZSS6
organism: Arabidopsis thaliana

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Aspartate semialdehyde dehydrogenase
type: Protein
entity reference: Aspartate semialdehyde dehydrogenase

ReactionCatalysis7165
type: Catalysis
controller: Aspartate aminotransferase 3, chloroplastic
controlled: 2.6.1.1
control type: ACTIVATION

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

2-iminobutanoate
type: SmallMolecule
cellular location: Chloroplast
entity reference: 2-iminobutanoate

Reference/PubChem-compound 12647
type: UnificationXref
id: 12647
db: PubChem-compound

Arabidopsis thaliana
type: BioSource
xref: Reference/TAXONOMY 3702

Reference/HMDB HMDB0012250
type: UnificationXref
id: HMDB0012250
db: HMDB

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000148
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CC(=O)C(O)=O

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/BioCyc L-BETA-ASPARTYL-P
type: UnificationXref
id: L-BETA-ASPARTYL-P
db: BioCyc

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Reference/SMPDB SMP0002444
type: UnificationXref
id: SMP0002444
db: SMPDB

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

ReactionCatalysis7293
type: Catalysis
controller: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
controlled: Reaction7321
control type: ACTIVATION

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

ReactionCatalysis7292
type: Catalysis
controller: Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
controlled: 1.2.1.4
control type: ACTIVATION

ReactionCatalysis7291
type: Catalysis
controller: Threonine synthase 1, chloroplastic
controlled: 4.2.3.1
control type: ACTIVATION

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00188
type: UnificationXref
id: C00188
db: KEGG Compound

Reference/ChEBI CHEBI 17053
type: UnificationXref
id: CHEBI:17053
db: ChEBI

Reference/CAS 56-40-6
type: UnificationXref
id: 56-40-6
db: CAS

Acetaldehyde
type: SmallMolecule
entity reference: Acetaldehyde

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

ReactionCatalysis7290
type: Catalysis
controller: aspartate kinase / homoserine dehydrogenase
controlled: 2.7.2.4
control type: ACTIVATION

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/HMDB HMDB0000719
type: UnificationXref
id: HMDB0000719
db: HMDB

Reference/UniProt Q9LYU8
type: UnificationXref
id: Q9LYU8
db: UniProt

Reference/HMDB HMDB0000167
type: UnificationXref
id: HMDB0000167
db: HMDB

Compound/PW C000109/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Threonine
stoichiometric coefficient: 1.0

Acetaldehyde
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15343
xref: Reference/KEGG Compound C00084
xref: Reference/CAS 75-07-0
xref: Reference/BioCyc ACETALD
xref: Reference/ChemSpider 172
xref: Reference/PubChem-compound 177
xref: Reference/HMDB HMDB0000990
chemical formula: C2H4O
molecular weight: 44.026215
structure: ChemicalStructure/PW C000784

Reference/UniProt Q1WIQ6
type: UnificationXref
id: Q1WIQ6
db: UniProt

Reference/ChEBI CHEBI 15428
type: UnificationXref
id: CHEBI:15428
db: ChEBI

Compound/PW C007795/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartyl-4-phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 133252
type: UnificationXref
id: 133252
db: ChemSpider

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/PubChem-compound 151187
type: UnificationXref
id: 151187
db: PubChem-compound

L-Threonine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000167
xref: Reference/PubChem-compound 6288
xref: Reference/CAS 72-19-5
xref: Reference/ChemSpider 6051
xref: Reference/ChEBI CHEBI 16857
xref: Reference/KEGG Compound C00188
xref: Reference/BioCyc THR
chemical formula: C4H9NO3
molecular weight: 119.05824
structure: ChemicalStructure/PW C000109

O-Phosphohomoserine
type: SmallMolecule
entity reference: O-Phosphohomoserine

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

ChemicalStructure/PW C040940
type: ChemicalStructure
structure format: SMILES
structure data: CCC(=N)C([O-])=O

Aspartate kinase
type: Complex
component stoichiometry: Protein/10609 Chloroplast/Stoichiometry/2.0
cellular location: Chloroplast
component: Aspartokinase

Phosphate
type: SmallMolecule
entity reference: Phosphate

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/PubChem-compound 439235
type: UnificationXref
id: 439235
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/ChemSpider 730
type: UnificationXref
id: 730
db: ChemSpider

4.2.3.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000109 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001905 Chloroplast/Stoichiometry/1.0
right: Phosphate
right: L-Threonine
spontaneous: false
EC number: 4.2.3.1
left: Water
left: O-Phosphohomoserine
name: O-Phosphohomoserine + Water → L-Threonine + Phosphate
conversion direction: LEFT_TO_RIGHT

2.7.2.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007794 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000570 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: NADP
right: L-Homoserine
spontaneous: false
EC number: 2.7.2.4
left: Hydrogen Ion
left: L-Aspartate-semialdehyde
left: NADPH
name: Hydrogen Ion + L-Aspartate-semialdehyde + NADPH → L-Homoserine + NADP
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00084
type: UnificationXref
id: C00084
db: KEGG Compound

Reference/CAS 75-07-0
type: UnificationXref
id: 75-07-0
db: CAS

Adenosine triphosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Adenosine triphosphate

Reference/ChemSpider 172
type: UnificationXref
id: 172
db: ChemSpider

Reference/CAS 15106-57-7
type: UnificationXref
id: 15106-57-7
db: CAS

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Oxalacetic acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: Oxalacetic acid

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Chloroplast
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0009507

Reference/UniProt O23653
type: UnificationXref
id: O23653
db: UniProt

Reference/PubChem-compound 832
type: UnificationXref
id: 832
db: PubChem-compound

Reference/PathWhiz PW002554
type: UnificationXref
id: PW002554
db: PathWhiz

Reference/BioCyc ACETALD
type: UnificationXref
id: ACETALD
db: BioCyc

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Acetaldehyde
type: SmallMolecule
cellular location: Cytosol
entity reference: Acetaldehyde

Compound/PW C001104 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

L-Aspartyl-4-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc L-BETA-ASPARTYL-P
xref: Reference/KEGG Compound C03082
xref: Reference/ChemSpider 809
xref: Reference/PubChem-compound 832
xref: Reference/CAS 22138-53-0
xref: Reference/HMDB HMDB0012250
chemical formula: C4H8NO7P
molecular weight: 213.00385
structure: ChemicalStructure/PW C007795

Threonine dehydratase biosynthetic, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Threonine dehydratase biosynthetic, chloroplastic

Protein/11158 Chloroplast/Stoichiometry/4.0
type: Stoichiometry
physical entity: Threonine dehydratase biosynthetic, chloroplastic
stoichiometric coefficient: 4.0

ChemicalStructure/PW C000784
type: ChemicalStructure
structure format: SMILES
structure data: CC=O

Aspartate aminotransferase 3, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Aspartate aminotransferase 3, chloroplastic

L-Aspartate-semialdehyde
type: SmallMolecule
entity reference: L-Aspartate-semialdehyde

L-Aspartyl-4-phosphate
type: SmallMolecule
entity reference: L-Aspartyl-4-phosphate

Reference/ChEBI CHEBI 30744
type: UnificationXref
id: CHEBI:30744
db: ChEBI

2-Ketobutyric acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 30831
xref: Reference/HMDB HMDB0000005
xref: Reference/CAS 600-18-0
xref: Reference/ChemSpider 57
xref: Reference/KEGG Compound C00109
xref: Reference/PubChem-compound 58
xref: Reference/BioCyc 2-OXOBUTANOATE
chemical formula: C4H6O3
molecular weight: 102.03169
structure: ChemicalStructure/PW C000003

L-Aspartic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 44367445
xref: Reference/ChemSpider 5745
xref: Reference/ChEBI CHEBI 17053
xref: Reference/HMDB HMDB0000191
xref: Reference/CAS 56-84-8
xref: Reference/KEGG Compound C00049
xref: Reference/BioCyc L-ASPARTATE
chemical formula: C4H7NO4
molecular weight: 133.0375
structure: ChemicalStructure/PW C000123

L-Aspartate-semialdehyde
type: SmallMoleculeReference
xref: Reference/PubChem-compound 439235
xref: Reference/HMDB HMDB0012249
xref: Reference/ChEBI CHEBI 18051
xref: Reference/KEGG Compound C00441
xref: Reference/ChemSpider 388372
xref: Reference/CAS 15106-57-7
xref: Reference/BioCyc L-ASPARTATE-SEMIALDEHYDE
chemical formula: C4H7NO3
molecular weight: 117.042595
structure: ChemicalStructure/PW C007794

NADPH
type: SmallMolecule
cellular location: Chloroplast
entity reference: NADPH

Homoserine kinase
type: ProteinReference
xref: Reference/UniProt Q8L7R2

Aspartate aminotransferase 3, chloroplastic
type: ProteinReference
xref: Reference/UniProt P46644
organism: Arabidopsis thaliana

Reference/ChEBI CHEBI 15343
type: UnificationXref
id: CHEBI:15343
db: ChEBI

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

Reference/ChemSpider 388372
type: UnificationXref
id: 388372
db: ChemSpider

Threonine synthase 1, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Threonine synthase 1, chloroplastic

Reference/BioCyc L-ASPARTATE-SEMIALDEHYDE
type: UnificationXref
id: L-ASPARTATE-SEMIALDEHYDE
db: BioCyc

Adenosine diphosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Adenosine diphosphate

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/BioCyc HOMO-SER
type: UnificationXref
id: HOMO-SER
db: BioCyc

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Reference/ChEBI CHEBI 18051
type: UnificationXref
id: CHEBI:18051
db: ChEBI

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C000078
type: ChemicalStructure
structure format: SMILES
structure data: NCC(O)=O

Compound/PW C000148 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxalacetic acid
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000191
type: UnificationXref
id: HMDB0000191
db: HMDB

Compound/PW C001905 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: O-Phosphohomoserine
stoichiometric coefficient: 1.0

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

L-Homoserine
type: SmallMoleculeReference
xref: Reference/BioCyc HOMO-SER
xref: Reference/ChEBI CHEBI 15699
xref: Reference/CAS 672-15-1
xref: Reference/KEGG Compound C00263
xref: Reference/PubChem-compound 12647
xref: Reference/HMDB HMDB0000719
xref: Reference/ChemSpider 12126
chemical formula: C4H9NO3
molecular weight: 119.05824
structure: ChemicalStructure/PW C000570

Reference/HMDB HMDB0000990
type: UnificationXref
id: HMDB0000990
db: HMDB

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Compound/PW C040939 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2Z)-2-aminobut-2-enoate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Compound/PW C000570 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Homoserine
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

ReactionCatalysis7252
type: Catalysis
controller: Aspartate semialdehyde dehydrogenase
controlled: Reaction7271
control type: ACTIVATION

Compound/PW C000123 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartic acid
stoichiometric coefficient: 1.0

Transport580
type: Transport
participant stoichiometry: Compound/PW C000784 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000784 Cytosol/Stoichiometry/1.0
right: Acetaldehyde
spontaneous: false
left: Acetaldehyde
name: Acetaldehyde (→) Transport: Arabidopsis thaliana, Cytosol to Arabidopsis thaliana, Cell, Mitochondrion
conversion direction: LEFT_TO_RIGHT

Reference/CAS 56-84-8
type: UnificationXref
id: 56-84-8
db: CAS

Compound/PW C000003 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Ketobutyric acid
stoichiometric coefficient: 1.0

L-Threonine
type: SmallMolecule
entity reference: L-Threonine

Reference/PubChem-compound 177
type: UnificationXref
id: 177
db: PubChem-compound

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Reference/PubChem-compound 970
type: UnificationXref
id: 970
db: PubChem-compound

4.1.2.48
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000109/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000078/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000784/Stoichiometry/1.0
right: Glycine
right: Acetaldehyde
spontaneous: false
EC number: 4.1.2.48
left: L-Threonine
name: L-Threonine → Acetaldehyde + Glycine
conversion direction: LEFT_TO_RIGHT

1.2.1.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000784/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADH
right: Hydrogen Ion
right: Acetyl-CoA
spontaneous: false
EC number: 1.2.1.4
left: Coenzyme A
left: NAD
left: Acetaldehyde
name: Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reaction7321
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000784/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADH
right: Hydrogen Ion
right: Acetyl-CoA
spontaneous: false
left: Coenzyme A
left: NAD
left: Acetaldehyde
name: Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT