LysoPE(14:0/0:0)
type: SmallMolecule
cellular location: Cell Membrane
entity reference: LysoPE(14:0/0:0)

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/KEGG Compound C02737
type: UnificationXref
id: C02737
db: KEGG Compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Compound/PW C005005/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE(16:1(9Z)/16:1(9Z))
stoichiometric coefficient: 1.0

Reference/BioCyc L-1-PHOSPHATIDYL-ETHANOLAMINE
type: UnificationXref
id: L-1-PHOSPHATIDYL-ETHANOLAMINE
db: BioCyc

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Lyso-PS(0:0/14:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Lyso-PS(0:0/14:0)

Reference/ChEBI CHEBI 15958
type: UnificationXref
id: CHEBI:15958
db: ChEBI

Reference/ChEBI CHEBI 84299
type: UnificationXref
id: CHEBI:84299
db: ChEBI

Reference/HMDB HMDB0001185
type: UnificationXref
id: HMDB0001185
db: HMDB

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C045277 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lyso-PS(0:0/14:0)
stoichiometric coefficient: 1.0

Reference/UniProt P05375
type: UnificationXref
id: P05375
db: UniProt

Reference/UniProt P05374
type: UnificationXref
id: P05374
db: UniProt

Phosphatidyl-N-methylethanolamine N-methyltransferase
type: Protein
entity reference: Phosphatidyl-N-methylethanolamine N-methyltransferase

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Phospholipid-transporting ATPase DNF1
type: Protein
cellular location: Cell Membrane
entity reference: Phospholipid-transporting ATPase DNF1

Phosphatidylethanolamine N-methyltransferase
type: Protein
entity reference: Phosphatidylethanolamine N-methyltransferase

Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/KEGG Compound C01241
type: UnificationXref
id: C01241
db: KEGG Compound

ReactionCoupledTransport307
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C006392 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004051 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: PC(16:1(9Z)/16:1(9Z))
spontaneous: false
left: LysoPC(16:1(9Z)/0:0)
name: LysoPC(16:1(9Z)/0:0) → PC(16:1(9Z)/16:1(9Z))
conversion direction: LEFT_TO_RIGHT

Compound/PW C045278 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lyso-PI(0:0/14:0)
stoichiometric coefficient: 1.0

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

ChemicalStructure/PW C007097
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 24778764
type: UnificationXref
id: 24778764
db: PubChem-compound

S-Adenosylmethionine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 24762165
xref: Reference/KEGG Compound C00019
xref: Reference/ChemSpider 31983
xref: Reference/ChEBI CHEBI 15414
xref: Reference/CAS 485-80-3
xref: Reference/BioCyc S-ADENOSYLMETHIONINE
xref: Reference/HMDB HMDB0001185
chemical formula: C15H23N6O5S
molecular weight: 399.14505
structure: ChemicalStructure/PW C000921

Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Lyso-PI(0:0/14:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Lyso-PI(0:0/14:0)

Compound/PW C045275 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lyso-PI(14:0/0:0)
stoichiometric coefficient: 1.0

ReactionCoupledTransport215
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C045276 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045278 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: PI(14:0/14:0)
spontaneous: false
left: Lyso-PI(0:0/14:0)
name: Lyso-PI(0:0/14:0) → PI(14:0/14:0)
conversion direction: LEFT_TO_RIGHT

Reference/CAS 76790-27-7
type: UnificationXref
id: 76790-27-7
db: CAS

ReactionCoupledTransport213
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C007860 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045277 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: PS(14:0/14:0)
spontaneous: false
left: Lyso-PS(0:0/14:0)
name: Lyso-PS(0:0/14:0) → PS(14:0/14:0)
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0008957
type: UnificationXref
id: HMDB0008957
db: HMDB

ReactionCoupledTransport214
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C045278 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Adenosine diphosphate
right: Phosphate
right: Lyso-PI(0:0/14:0)
spontaneous: false
left: Lyso-PI(0:0/14:0)
left: Adenosine triphosphate
left: Water
name: Adenosine triphosphate + Lyso-PI(0:0/14:0) + Water → Adenosine diphosphate + Lyso-PI(0:0/14:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C007860
type: ChemicalStructure
structure format: SMILES

ReactionCoupledTransport211
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C045276 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045275 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: PI(14:0/14:0)
spontaneous: false
left: Lyso-PI(14:0/0:0)
name: Lyso-PI(14:0/0:0) → PI(14:0/14:0)
conversion direction: LEFT_TO_RIGHT

ReactionCoupledTransport212
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045277 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Adenosine diphosphate
right: Phosphate
right: Lyso-PS(0:0/14:0)
spontaneous: false
left: Lyso-PS(0:0/14:0)
left: Adenosine triphosphate
left: Water
name: Adenosine triphosphate + Lyso-PS(0:0/14:0) + Water → Adenosine diphosphate + Lyso-PS(0:0/14:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

ReactionCoupledTransport210
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C045275 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Adenosine diphosphate
right: Phosphate
right: Lyso-PI(14:0/0:0)
spontaneous: false
left: Lyso-PI(14:0/0:0)
left: Adenosine triphosphate
left: Water
name: Adenosine triphosphate + Lyso-PI(14:0/0:0) + Water → Adenosine diphosphate + Lyso-PI(14:0/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

PC(16:1(9Z)/16:1(9Z))
type: SmallMoleculeReference
xref: Reference/PubChem-compound 24778764
xref: Reference/ChEBI CHEBI 83717
xref: Reference/HMDB HMDB0008002
xref: Reference/KEGG Compound C00157
xref: Reference/BioCyc PHOSPHATIDYLCHOLINE
xref: Reference/ChemSpider 24766671
chemical formula: C40H76NO8P
molecular weight: 729.5309
structure: ChemicalStructure/PW C004051

Reference/BioCyc CPD-405
type: UnificationXref
id: CPD-405
db: BioCyc

ChemicalStructure/PW C057492
type: ChemicalStructure
structure format: SMILES

Phosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Phosphate

Reference/ChEBI CHEBI 18303
type: UnificationXref
id: CHEBI:18303
db: ChEBI

Reference/BioCyc ADENOSYL-HOMO-CYS
type: UnificationXref
id: ADENOSYL-HOMO-CYS
db: BioCyc

Lyso-PS(14:0/0:0)
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Lyso-PS(14:0/0:0)

Reference/CAS 485-80-3
type: UnificationXref
id: 485-80-3
db: CAS

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Compound/PW C045274 Endoplasmic Reticulum/Stoichiometry/2.0
type: Stoichiometry
physical entity: Lyso-PS(14:0/0:0)
stoichiometric coefficient: 2.0

Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/ChEBI CHEBI 73851
type: UnificationXref
id: CHEBI:73851
db: ChEBI

PI(14:0/14:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: PI(14:0/14:0)

ReactionCoupledTransport208
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045274 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Adenosine diphosphate
right: Phosphate
right: Lyso-PS(14:0/0:0)
spontaneous: false
left: Lyso-PS(14:0/0:0)
left: Adenosine triphosphate
left: Water
name: Adenosine triphosphate + Lyso-PS(14:0/0:0) + Water → Adenosine diphosphate + Lyso-PS(14:0/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Saccharomyces cerevisiae
type: BioSource
xref: Reference/TAXONOMY 4932

ReactionCoupledTransport209
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C007860 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045274 Endoplasmic Reticulum/Stoichiometry/2.0
right: PS(14:0/14:0)
spontaneous: false
left: Lyso-PS(14:0/0:0)
name: 2 Lyso-PS(14:0/0:0) → PS(14:0/14:0)
conversion direction: LEFT_TO_RIGHT

ReactionCoupledTransport207
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007097 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: LysoPE(14:0/0:0)
right: Adenosine diphosphate
right: Phosphate
spontaneous: false
left: LysoPE(14:0/0:0)
left: Adenosine triphosphate
left: Water
name: Adenosine triphosphate + LysoPE(14:0/0:0) + Water → Adenosine diphosphate + LysoPE(14:0/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C045278 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lyso-PI(0:0/14:0)
stoichiometric coefficient: 1.0

ChemicalStructure/PW C045278
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C045277
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCC(=O)OC(CO)COP([O-])(=O)OCC([NH3+])C([O-])=O

Compound/PW C057650/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE-NMe2(16:1(9Z)/16:1(9Z))
stoichiometric coefficient: 1.0

ChemicalStructure/PW C045274
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCC(=O)OCC(O)COP([O-])(=O)OCC([NH3+])C([O-])=O

Reference/ChemSpider 110272
type: UnificationXref
id: 110272
db: ChemSpider

ChemicalStructure/PW C045276
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C045275
type: ChemicalStructure
structure format: SMILES

Phosphatidyl-N-methylethanolamine N-methyltransferase
type: ProteinReference
xref: Reference/UniProt P05375

Phosphatidylethanolamine N-methyltransferase
type: ProteinReference
xref: Reference/UniProt P05374

Phospholipid-transporting ATPase DNF2
type: Protein
cellular location: Cell Membrane
entity reference: Phospholipid-transporting ATPase DNF2

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

ChemicalStructure/PW C000921
type: ChemicalStructure
structure format: SMILES

Reference/CAS 979-92-0
type: UnificationXref
id: 979-92-0
db: CAS

ReactionCoupledTransportCatalysis254
type: Catalysis
controller: Ale1p acyltransferase
controlled: ReactionCoupledTransport465
control type: ACTIVATION

Compound/PW C045274 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lyso-PS(14:0/0:0)
stoichiometric coefficient: 1.0

ReactionCoupledTransportCatalysis253
type: Catalysis
controller: Ale1p acyltransferase
controlled: ReactionCoupledTransport307
control type: ACTIVATION

ReactionCoupledTransportCatalysis252
type: Catalysis
controller: Ale1p acyltransferase
controlled: ReactionCoupledTransport215
control type: ACTIVATION

Reference/KEGG Compound C00350
type: UnificationXref
id: C00350
db: KEGG Compound

ReactionCoupledTransportCatalysis251
type: Catalysis
controller: Phospholipid-transporting ATPase
controlled: ReactionCoupledTransport214
control type: ACTIVATION

ReactionCoupledTransportCatalysis250
type: Catalysis
controller: Ale1p acyltransferase
controlled: ReactionCoupledTransport213
control type: ACTIVATION

Reference/BioCyc PHOSPHATIDYLCHOLINE
type: UnificationXref
id: PHOSPHATIDYLCHOLINE
db: BioCyc

S-Adenosylhomocysteine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 25246222
xref: Reference/ChemSpider 388301
xref: Reference/BioCyc ADENOSYL-HOMO-CYS
xref: Reference/CAS 979-92-0
xref: Reference/KEGG Compound C00021
xref: Reference/ChEBI CHEBI 16680
xref: Reference/HMDB HMDB0000939
chemical formula: C14H20N6O5S
molecular weight: 384.12158
structure: ChemicalStructure/PW C000749

Reference/ChemSpider 24766671
type: UnificationXref
id: 24766671
db: ChemSpider

PS(14:0/14:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: PS(14:0/14:0)

Compound/PW C057492/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE-NMe(16:1(9Z)/16:1(9Z))
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/GENE ONTOLOGY GO 0005886
type: UnificationXref
id: GO:0005886
db: GENE ONTOLOGY

ChemicalStructure/PW C004051
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@](COC(=O)CCCCCCC\C=C/CCCCCC)(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/CCCCCC

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/HMDB HMDB0010383
type: UnificationXref
id: HMDB0010383
db: HMDB

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Ale1p acyltransferase
type: Protein
cellular location: Endoplasmic Reticulum
entity reference: Ale1p acyltransferase

Reference/ChEBI CHEBI 15414
type: UnificationXref
id: CHEBI:15414
db: ChEBI

PE-NMe(16:1(9Z)/16:1(9Z))
type: SmallMoleculeReference
xref: Reference/KEGG Compound C01241
xref: Reference/BioCyc CPD-405
xref: Reference/ChEBI CHEBI 15958
xref: Reference/HMDB HMDB0112948
chemical formula: C38H72NO8P
molecular weight: 701.4996
structure: ChemicalStructure/PW C057492

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Phospholipid-transporting ATPase
type: Complex
cellular location: Cell Membrane
component: Phospholipid-transporting ATPase DNF2
component: Alkylphosphocholine resistance protein LEM3
component: Phospholipid-transporting ATPase DNF1

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Compound/PW C007860 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PS(14:0/14:0)
stoichiometric coefficient: 1.0

PE(16:1(9Z)/16:1(9Z))
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: PE(16:1(9Z)/16:1(9Z))

Reference/ChEBI CHEBI 83717
type: UnificationXref
id: CHEBI:83717
db: ChEBI

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

Lyso-PS(14:0/0:0)
type: SmallMoleculeReference
chemical formula: C20H39NO9P
molecular weight: 468.2368
structure: ChemicalStructure/PW C045274

ReactionCoupledTransport465
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C007097 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C005005 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: PE(16:1(9Z)/16:1(9Z))
spontaneous: false
left: LysoPE(14:0/0:0)
name: LysoPE(14:0/0:0) → PE(16:1(9Z)/16:1(9Z))
conversion direction: LEFT_TO_RIGHT

Lyso-PI(14:0/0:0)
type: SmallMoleculeReference
chemical formula: C23H45O12P
molecular weight: 544.2649
structure: ChemicalStructure/PW C045275

Reference/UniProt Q12675
type: UnificationXref
id: Q12675
db: UniProt

Lyso-PI(0:0/14:0)
type: SmallMoleculeReference
chemical formula: C23H45O12P
molecular weight: 544.2649
structure: ChemicalStructure/PW C045278

PI(14:0/14:0)
type: SmallMoleculeReference
chemical formula: C37H71O13P
molecular weight: 754.46326
structure: ChemicalStructure/PW C045276

Lyso-PS(0:0/14:0)
type: SmallMoleculeReference
chemical formula: C20H39NO9P
molecular weight: 468.2368
structure: ChemicalStructure/PW C045277

Reference/KEGG Compound C00019
type: UnificationXref
id: C00019
db: KEGG Compound

Ale1p acyltransferase
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Ale1p acyltransferase

Reference/BioCyc S-ADENOSYLMETHIONINE
type: UnificationXref
id: S-ADENOSYLMETHIONINE
db: BioCyc

LysoPC(16:1(9Z)/0:0)
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: LysoPC(16:1(9Z)/0:0)

Reference/PubChem-compound 123699
type: UnificationXref
id: 123699
db: PubChem-compound

PE-NMe(16:1(9Z)/16:1(9Z))
type: SmallMolecule
entity reference: PE-NMe(16:1(9Z)/16:1(9Z))

Reference/HMDB HMDB0012330
type: UnificationXref
id: HMDB0012330
db: HMDB

Reference/ChEBI CHEBI 52332
type: UnificationXref
id: CHEBI:52332
db: ChEBI

ChemicalStructure/PW C005005
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

LysoPC(16:1(9Z)/0:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C04230
xref: Reference/HMDB HMDB0010383
xref: Reference/CAS 76790-27-7
xref: Reference/ChemSpider 24766525
xref: Reference/PubChem-compound 24779461
xref: Reference/BioCyc PHOSPHATIDYLCHOLINE
xref: Reference/ChEBI CHEBI 73851
chemical formula: C24H48NO7P
molecular weight: 493.31683
structure: ChemicalStructure/PW C006392

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

Compound/PW C045275 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lyso-PI(14:0/0:0)
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChemSpider 388301
type: UnificationXref
id: 388301
db: ChemSpider

S-Adenosylhomocysteine
type: SmallMolecule
entity reference: S-Adenosylhomocysteine

Compound/PW C045276 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PI(14:0/14:0)
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00021
type: UnificationXref
id: C00021
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/PubChem-compound 9546809
type: UnificationXref
id: 9546809
db: PubChem-compound

Compound/PW C000921/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylmethionine
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

ReactionCoupledTransport244
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006392 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Adenosine diphosphate
right: Phosphate
right: LysoPC(16:1(9Z)/0:0)
spontaneous: false
left: LysoPC(16:1(9Z)/0:0)
left: Adenosine triphosphate
left: Water
name: Adenosine triphosphate + LysoPC(16:1(9Z)/0:0) + Water → Adenosine diphosphate + LysoPC(16:1(9Z)/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis7386
type: Catalysis
controller: Phosphatidyl-N-methylethanolamine N-methyltransferase
controlled: Reaction7545
control type: ACTIVATION

ReactionCatalysis7385
type: Catalysis
controller: Phosphatidyl-N-methylethanolamine N-methyltransferase
controlled: 2.1.1.17,2.1.1.71
control type: ACTIVATION

ReactionCatalysis7384
type: Catalysis
controller: Phosphatidylethanolamine N-methyltransferase
controlled: 2.1.1.17
control type: ACTIVATION

Endoplasmic Reticulum
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005783

Endoplasmic Reticulum Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005789

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/HMDB HMDB0113849
type: UnificationXref
id: HMDB0113849
db: HMDB

Reference/KEGG Compound C00157
type: UnificationXref
id: C00157
db: KEGG Compound

Adenosine triphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Adenosine triphosphate

ChemicalStructure/PW C006392
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C

PS(14:0/14:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18303
xref: Reference/BioCyc L-1-PHOSPHATIDYL-SERINE
xref: Reference/KEGG Compound C02737
xref: Reference/PubChem-compound 123699
xref: Reference/HMDB HMDB0012330
xref: Reference/ChemSpider 110272
chemical formula: C34H66NO10P
molecular weight: 679.44244
structure: ChemicalStructure/PW C007860

Reference/UniProt P42838
type: UnificationXref
id: P42838
db: UniProt

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/ChemSpider 24766525
type: UnificationXref
id: 24766525
db: ChemSpider

Compound/PW C045277 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lyso-PS(0:0/14:0)
stoichiometric coefficient: 1.0

Compound/PW C006392 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPC(16:1(9Z)/0:0)
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Water

Reference/HMDB HMDB0000939
type: UnificationXref
id: HMDB0000939
db: HMDB

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 86583448
type: UnificationXref
id: 86583448
db: PubChem-compound

Compound/PW C007097 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPE(14:0/0:0)
stoichiometric coefficient: 1.0

Lyso-PS(14:0/0:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Lyso-PS(14:0/0:0)

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 7825759
type: UnificationXref
id: 7825759
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C005005 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE(16:1(9Z)/16:1(9Z))
stoichiometric coefficient: 1.0

Reference/GENE ONTOLOGY GO 0005789
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

Compound/PW C004051/Stoichiometry/1.0
type: Stoichiometry
physical entity: PC(16:1(9Z)/16:1(9Z))
stoichiometric coefficient: 1.0

Reference/GENE ONTOLOGY GO 0005783
type: UnificationXref
id: GO:0005783
db: GENE ONTOLOGY

ReactionCoupledTransportCatalysis249
type: Catalysis
controller: Phospholipid-transporting ATPase
controlled: ReactionCoupledTransport212
control type: ACTIVATION

ReactionCoupledTransportCatalysis248
type: Catalysis
controller: Ale1p acyltransferase
controlled: ReactionCoupledTransport211
control type: ACTIVATION

Reference/KEGG Compound C04308
type: UnificationXref
id: C04308
db: KEGG Compound

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

ReactionCoupledTransportCatalysis247
type: Catalysis
controller: Phospholipid-transporting ATPase
controlled: ReactionCoupledTransport210
control type: ACTIVATION

ReactionCoupledTransportCatalysis246
type: Catalysis
controller: Ale1p acyltransferase
controlled: ReactionCoupledTransport209
control type: ACTIVATION

ReactionCoupledTransportCatalysis245
type: Catalysis
controller: Phospholipid-transporting ATPase
controlled: ReactionCoupledTransport208
control type: ACTIVATION

ReactionCoupledTransportCatalysis244
type: Catalysis
controller: Phospholipid-transporting ATPase
controlled: ReactionCoupledTransport207
control type: ACTIVATION

ReactionCoupledTransportCatalysis243
type: Catalysis
controller: Phospholipid-transporting ATPase
controlled: ReactionCoupledTransport244
control type: ACTIVATION

Reference/PubChem-compound 24779461
type: UnificationXref
id: 24779461
db: PubChem-compound

PS(14:0/14:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: PS(14:0/14:0)

ChemicalStructure/PW C057650
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Lysolipid Incorporation into Mitochondria PC(16:1(9Z)/16:1(9Z))
type: Pathway
pathway order: PathwayEnzymeReaction/2189086
pathway order: PathwayEnzymeReaction/2189087
pathway order: PathwayEnzymeReaction/2189088
pathway order: PathwayEnzymeReaction/2189099
pathway order: PathwayEnzymeReaction/2189089
pathway order: PathwayEnzymeReaction/2189100
pathway order: PathwayEnzymeReaction/2189101
pathway order: PathwayEnzymeReaction/2189090
pathway order: PathwayEnzymeReaction/2189091
pathway order: PathwayEnzymeReaction/2189092
pathway order: PathwayEnzymeReaction/2189093
pathway order: PathwayEnzymeReaction/2189094
pathway order: PathwayEnzymeReaction/2189095
pathway order: PathwayEnzymeReaction/2189085
pathway order: PathwayEnzymeReaction/2189096
pathway component: ReactionCatalysis7386
pathway component: ReactionCatalysis7385
pathway component: ReactionCatalysis7384
pathway component: ReactionCoupledTransportCatalysis254
pathway component: ReactionCoupledTransportCatalysis253
pathway component: ReactionCoupledTransportCatalysis252
pathway component: ReactionCoupledTransportCatalysis251
pathway component: ReactionCoupledTransportCatalysis250
pathway component: ReactionCoupledTransport215
pathway component: ReactionCoupledTransport213
pathway component: ReactionCoupledTransport214
pathway component: ReactionCoupledTransport211
pathway component: ReactionCoupledTransport212
pathway component: ReactionCoupledTransport210
pathway component: ReactionCoupledTransportCatalysis249
pathway component: ReactionCoupledTransportCatalysis248
pathway component: ReactionCoupledTransportCatalysis247
pathway component: ReactionCoupledTransportCatalysis246
pathway component: ReactionCoupledTransportCatalysis245
pathway component: ReactionCoupledTransportCatalysis244
pathway component: ReactionCoupledTransportCatalysis243
pathway component: ReactionCoupledTransport307
pathway component: ReactionCoupledTransport208
pathway component: ReactionCoupledTransport209
pathway component: ReactionCoupledTransport207
pathway component: ReactionCoupledTransport244
pathway component: ReactionCoupledTransport465
pathway component: 2.1.1.17,2.1.1.71
pathway component: 2.1.1.17
pathway component: Reaction7545
xref: Reference/PathWhiz PW002793
xref: Reference/SMPDB SMP0002523
organism: Saccharomyces cerevisiae

Alkylphosphocholine resistance protein LEM3
type: Protein
cellular location: Cell Membrane
entity reference: Alkylphosphocholine resistance protein LEM3

Lyso-PI(14:0/0:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Lyso-PI(14:0/0:0)

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Compound/PW C007097 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPE(14:0/0:0)
stoichiometric coefficient: 1.0

Reference/ChemSpider 31983
type: UnificationXref
id: 31983
db: ChemSpider

LysoPC(16:1(9Z)/0:0)
type: SmallMolecule
cellular location: Cell Membrane
entity reference: LysoPC(16:1(9Z)/0:0)

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Lyso-PI(14:0/0:0)
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Lyso-PI(14:0/0:0)

Compound/PW C004051 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PC(16:1(9Z)/16:1(9Z))
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0011500
type: UnificationXref
id: HMDB0011500
db: HMDB

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/ChemSpider 7826020
type: UnificationXref
id: 7826020
db: ChemSpider

PE(16:1(9Z)/16:1(9Z))
type: SmallMoleculeReference
xref: Reference/PubChem-compound 9546809
xref: Reference/BioCyc L-1-PHOSPHATIDYL-ETHANOLAMINE
xref: Reference/ChEBI CHEBI 16337
xref: Reference/ChemSpider 7825759
xref: Reference/HMDB HMDB0008957
xref: Reference/KEGG Compound C00350
chemical formula: C37H70NO8P
molecular weight: 687.4839
structure: ChemicalStructure/PW C005005

PC(16:1(9Z)/16:1(9Z))
type: SmallMolecule
entity reference: PC(16:1(9Z)/16:1(9Z))

Reference/UniProt P32660
type: UnificationXref
id: P32660
db: UniProt

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Cell Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005886

Phospholipid-transporting ATPase DNF2
type: ProteinReference
xref: Reference/UniProt Q12675
organism: Saccharomyces cerevisiae

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Phospholipid-transporting ATPase DNF1
type: ProteinReference
xref: Reference/UniProt P32660
organism: Saccharomyces cerevisiae

Ale1p acyltransferase
type: ProteinReference
organism: Saccharomyces cerevisiae

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Alkylphosphocholine resistance protein LEM3
type: ProteinReference
xref: Reference/UniProt P42838
organism: Saccharomyces cerevisiae

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/PathWhiz PW002793
type: UnificationXref
id: PW002793
db: PathWhiz

Reference/BioCyc L-1-PHOSPHATIDYL-SERINE
type: UnificationXref
id: L-1-PHOSPHATIDYL-SERINE
db: BioCyc

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

PE-NMe2(16:1(9Z)/16:1(9Z))
type: SmallMoleculeReference
xref: Reference/KEGG Compound C04308
xref: Reference/HMDB HMDB0113849
xref: Reference/BioCyc CPD-160
xref: Reference/ChEBI CHEBI 52332
chemical formula: C39H74NO8P
molecular weight: 715.5152
structure: ChemicalStructure/PW C057650

S-Adenosylmethionine
type: SmallMolecule
entity reference: S-Adenosylmethionine

Compound/PW C007860 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: PS(14:0/14:0)
stoichiometric coefficient: 1.0

2.1.1.17,2.1.1.71
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057492/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057650/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: PE-NMe2(16:1(9Z)/16:1(9Z))
spontaneous: false
EC number: 2.1.1.17,2.1.1.71
left: PE-NMe(16:1(9Z)/16:1(9Z))
left: S-Adenosylmethionine
name: PE-NMe(16:1(9Z)/16:1(9Z)) + S-Adenosylmethionine → Hydrogen Ion + PE-NMe2(16:1(9Z)/16:1(9Z)) + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

2.1.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057492/Stoichiometry/1.0
participant stoichiometry: Compound/PW C005005/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: PE-NMe(16:1(9Z)/16:1(9Z))
spontaneous: false
EC number: 2.1.1.17
left: PE(16:1(9Z)/16:1(9Z))
left: S-Adenosylmethionine
name: PE(16:1(9Z)/16:1(9Z)) + S-Adenosylmethionine → Hydrogen Ion + PE-NMe(16:1(9Z)/16:1(9Z)) + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

Reaction7545
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004051/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057650/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: PC(16:1(9Z)/16:1(9Z))
spontaneous: false
left: PE-NMe2(16:1(9Z)/16:1(9Z))
left: S-Adenosylmethionine
name: PE-NMe2(16:1(9Z)/16:1(9Z)) + S-Adenosylmethionine → Hydrogen Ion + PC(16:1(9Z)/16:1(9Z)) + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

Reference/TAXONOMY 4932
type: UnificationXref
id: 4932
db: TAXONOMY

Compound/PW C006392 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPC(16:1(9Z)/0:0)
stoichiometric coefficient: 1.0

Lyso-PI(0:0/14:0)
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Lyso-PI(0:0/14:0)

PE-NMe2(16:1(9Z)/16:1(9Z))
type: SmallMolecule
entity reference: PE-NMe2(16:1(9Z)/16:1(9Z))

ChemicalStructure/PW C000749
type: ChemicalStructure
structure format: SMILES

PE(16:1(9Z)/16:1(9Z))
type: SmallMolecule
entity reference: PE(16:1(9Z)/16:1(9Z))

Reference/PubChem-compound 25246222
type: UnificationXref
id: 25246222
db: PubChem-compound

Compound/PW C000749/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylhomocysteine
stoichiometric coefficient: 1.0

Lyso-PS(0:0/14:0)
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Lyso-PS(0:0/14:0)

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/SMPDB SMP0002523
type: UnificationXref
id: SMP0002523
db: SMPDB

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

LysoPE(14:0/0:0)
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: LysoPE(14:0/0:0)

Reference/ChEBI CHEBI 16680
type: UnificationXref
id: CHEBI:16680
db: ChEBI

Reference/HMDB HMDB0112948
type: UnificationXref
id: HMDB0112948
db: HMDB

Reference/BioCyc CPD-160
type: UnificationXref
id: CPD-160
db: BioCyc

Ale1p acyltransferase
type: Protein
cellular location: Mitochondrial Inner Membrane
entity reference: Ale1p acyltransferase

Reference/PubChem-compound 24762165
type: UnificationXref
id: 24762165
db: PubChem-compound

Reference/KEGG Compound C04230
type: UnificationXref
id: C04230
db: KEGG Compound

Adenosine diphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Adenosine diphosphate

LysoPE(14:0/0:0)
type: SmallMoleculeReference
xref: Reference/PubChem-compound 86583448
xref: Reference/ChemSpider 7826020
xref: Reference/HMDB HMDB0011500
xref: Reference/ChEBI CHEBI 84299
chemical formula: C19H40NO7P
molecular weight: 425.25424
structure: ChemicalStructure/PW C007097

Reference/HMDB HMDB0008002
type: UnificationXref
id: HMDB0008002
db: HMDB

PC(16:1(9Z)/16:1(9Z))
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: PC(16:1(9Z)/16:1(9Z))