Glycerol-3-phosphate O-acyltransferase 2
type: Protein
entity reference: Glycerol-3-phosphate O-acyltransferase 2

Glycerol-3-phosphate O-acyltransferase 1
type: Protein
entity reference: Glycerol-3-phosphate O-acyltransferase 1

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Triacylglycerol Metabolism TG(15:0/18:0/18:0)
type: Pathway
pathway order: PathwayEnzymeReaction/2455050
pathway order: PathwayEnzymeReaction/2455053
pathway order: PathwayEnzymeReaction/2455054
pathway order: PathwayEnzymeReaction/2455051
pathway order: PathwayEnzymeReaction/2455052
pathway order: PathwayEnzymeReaction/2455055
pathway order: PathwayEnzymeReaction/2455048
pathway order: PathwayEnzymeReaction/2455049
pathway component: 2.3.1.15
pathway component: 2.3.1.23
pathway component: ReactionCatalysis201058
pathway component: ReactionCatalysis201059
pathway component: 3.1.1.3
pathway component: 3.1.1.13
pathway component: 2.3.1.20
pathway component: 2.7.1.174
pathway component: 3.1.3.4
pathway component: 3.1.1.23
pathway component: ReactionCatalysis201060
pathway component: ReactionCatalysis201061
pathway component: ReactionCatalysis177066
pathway component: ReactionCatalysis177067
pathway component: ReactionCatalysis6971
pathway component: ReactionCatalysis6970
xref: Reference/SMPDB SMP0006934
xref: Reference/PathWhiz PW007792
organism: Saccharomyces cerevisiae

Reference/UniProt Q06508
type: UnificationXref
id: Q06508
db: UniProt

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/CAS 56-81-5
type: UnificationXref
id: 56-81-5
db: CAS

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6132
type: UnificationXref
id: 6132
db: PubChem-compound

Reference/ChEBI CHEBI 17239
type: UnificationXref
id: CHEBI:17239
db: ChEBI

ChemicalStructure/PW C062921
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5281
type: UnificationXref
id: 5281
db: PubChem-compound

Reference/KEGG Compound C01530
type: UnificationXref
id: C01530
db: KEGG Compound

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Triacylglycerol lipase complex
type: Complex
component: Lipase 3
component: Lipase 4
component: Lipase 5
component: Sterol esterase TGL1
component: Lipase 2

Reference/ChemSpider 388366
type: UnificationXref
id: 388366
db: ChemSpider

Reference/CAS 1002-84-2
type: UnificationXref
id: 1002-84-2
db: CAS

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Compound/PW C062231/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(15:0/18:0)
stoichiometric coefficient: 1.0

Lipase 3
type: ProteinReference
xref: Reference/UniProt P40308

Lipase 2
type: ProteinReference
xref: Reference/UniProt P54857

Lipase 5
type: ProteinReference
xref: Reference/UniProt Q12043

Lipase 4
type: ProteinReference
xref: Reference/UniProt P36165

Diacylglycerol O-acyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q08650

Sterol esterase TGL1
type: ProteinReference
xref: Reference/UniProt P34163

Reference/CAS 63-38-7
type: UnificationXref
id: 63-38-7
db: CAS

Monoglyceride lipase
type: ProteinReference
xref: Reference/UniProt P28321

Reference/UniProt Q12043
type: UnificationXref
id: Q12043
db: UniProt

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/HMDB HMDB0011564
type: UnificationXref
id: HMDB0011564
db: HMDB

Reference/ChemSpider 2341519
type: UnificationXref
id: 2341519
db: ChemSpider

Reference/HMDB HMDB0007071
type: UnificationXref
id: HMDB0007071
db: HMDB

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Saccharomyces cerevisiae
type: BioSource
xref: Reference/TAXONOMY 4932

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

TG(15:0/18:0/18:0)
type: SmallMolecule
entity reference: TG(15:0/18:0/18:0)

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Reference/UniProt P28321
type: UnificationXref
id: P28321
db: UniProt

Reference/BioCyc CPD-14724
type: UnificationXref
id: CPD-14724
db: BioCyc

Reference/KEGG Compound C00116
type: UnificationXref
id: C00116
db: KEGG Compound

Reference/ChEBI CHEBI 16975
type: UnificationXref
id: CHEBI:16975
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Compound/PW C023762/Stoichiometry/1.0
type: Stoichiometry
physical entity: TG(15:0/18:0/18:0)
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 42504
type: UnificationXref
id: CHEBI:42504
db: ChEBI

Reference/UniProt P54857
type: UnificationXref
id: P54857
db: UniProt

ChemicalStructure/PW C055364
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCC(=O)OCC(O)COP(O)(O)=O

Reference/KEGG Compound C00112
type: UnificationXref
id: C00112
db: KEGG Compound

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

CDP
type: SmallMolecule
entity reference: CDP

Reference/ChEBI CHEBI 28842
type: UnificationXref
id: CHEBI:28842
db: ChEBI

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0001546
type: UnificationXref
id: HMDB0001546
db: HMDB

DG(15:0/18:0/0:0)
type: SmallMolecule
entity reference: DG(15:0/18:0/0:0)

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5091
type: UnificationXref
id: 5091
db: ChemSpider

Stearoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 362-66-3
xref: Reference/ChEBI CHEBI 15541
xref: Reference/HMDB HMDB0001114
xref: Reference/KEGG Compound C00412
xref: Reference/BioCyc STEAROYL-COA
xref: Reference/ChemSpider 388366
xref: Reference/PubChem-compound 439229
chemical formula: C39H70N7O17P3S
molecular weight: 1033.3762
structure: ChemicalStructure/PW C000871

Reference/ChemSpider 24765904
type: UnificationXref
id: 24765904
db: ChemSpider

MG(16:0/0:0/0:0)
type: SmallMolecule
entity reference: MG(16:0/0:0/0:0)

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/ChEBI CHEBI 75542
type: UnificationXref
id: CHEBI:75542
db: ChEBI

Glycerol
type: SmallMolecule
entity reference: Glycerol

Reference/ChEBI CHEBI 74574
type: UnificationXref
id: CHEBI:74574
db: ChEBI

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

Glycerol-3-phosphate O-acyltransferase 2
type: ProteinReference
xref: Reference/UniProt P36148

Reference/BioCyc CDP
type: UnificationXref
id: CDP
db: BioCyc

Glycerol-3-phosphate O-acyltransferase 1
type: ProteinReference
xref: Reference/UniProt P32784

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

Reference/ChemSpider 13249
type: UnificationXref
id: 13249
db: ChemSpider

Glycerol
type: SmallMoleculeReference
xref: Reference/PubChem-compound 753
xref: Reference/KEGG Compound C00116
xref: Reference/ChEBI CHEBI 17522
xref: Reference/CAS 56-81-5
xref: Reference/BioCyc GLYCEROL
xref: Reference/HMDB HMDB0000131
xref: Reference/ChemSpider 733
chemical formula: C3H8O3
molecular weight: 92.04734
structure: ChemicalStructure/PW C000085

Acyl-CoA:lyso-phospholipid acyltransferase
type: ProteinReference
xref: Reference/UniProt Q08548

Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt P33333

Lipase 4
type: ProteinReference
xref: Reference/UniProt P36165

Lipase 3
type: Protein
entity reference: Lipase 3

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Reference/PubChem-compound 71581247
type: UnificationXref
id: 71581247
db: PubChem-compound

Stearoyl-CoA
type: SmallMolecule
entity reference: Stearoyl-CoA

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q06508

Lipase 5
type: ProteinReference
xref: Reference/UniProt Q12043

Reference/HMDB HMDB0043049
type: UnificationXref
id: HMDB0043049
db: HMDB

Phosphatidic acid phosphohydrolase 1
type: Protein
entity reference: Phosphatidic acid phosphohydrolase 1

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Compound/PW C000871/Stoichiometry/1.0
type: Stoichiometry
physical entity: Stearoyl-CoA
stoichiometric coefficient: 1.0

CTP-dependent diacylglycerol kinase 1
type: Protein
entity reference: CTP-dependent diacylglycerol kinase 1

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

ReactionCatalysis177066
type: Catalysis
controller: Glycerol-3-phosphate O-acyltransferase
controlled: 2.3.1.15
control type: ACTIVATION

ReactionCatalysis177067
type: Catalysis
controller: Lysophosphatidate acyltransferase
controlled: 2.3.1.23
control type: ACTIVATION

Compound/PW C003122/Stoichiometry/1.0
type: Stoichiometry
physical entity: DG(15:0/18:0/0:0)
stoichiometric coefficient: 1.0

ChemicalStructure/PW C062231
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc DIACYLGLYCEROL
type: UnificationXref
id: DIACYLGLYCEROL
db: BioCyc

Reference/UniProt P36148
type: UnificationXref
id: P36148
db: UniProt

Reference/CAS 32899-41-5
type: UnificationXref
id: 32899-41-5
db: CAS

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc STEARIC ACID
type: UnificationXref
id: STEARIC_ACID
db: BioCyc

ReactionCatalysis6971
type: Catalysis
controller: CTP-dependent diacylglycerol kinase 1
controlled: 2.7.1.174
control type: ACTIVATION

ReactionCatalysis6970
type: Catalysis
controller: Phosphatidic acid phosphohydrolase 1
controlled: 3.1.3.4
control type: ACTIVATION

Reference/BioCyc STEAROYL-COA
type: UnificationXref
id: STEAROYL-COA
db: BioCyc

Reference/HMDB HMDB0000131
type: UnificationXref
id: HMDB0000131
db: HMDB

Reference/PubChem-compound 753
type: UnificationXref
id: 753
db: PubChem-compound

Compound/PW C007160/Stoichiometry/1.0
type: Stoichiometry
physical entity: MG(16:0/0:0/0:0)
stoichiometric coefficient: 1.0

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/UniProt Q08650
type: UnificationXref
id: Q08650
db: UniProt

Reference/BioCyc GLYCEROL
type: UnificationXref
id: GLYCEROL
db: BioCyc

Reference/KEGG Compound C00165
type: UnificationXref
id: C00165
db: KEGG Compound

Compound/PW C001189/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Compound/PW C000661/Stoichiometry/1.0
type: Stoichiometry
physical entity: Stearic acid
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/HMDB HMDB0001114
type: UnificationXref
id: HMDB0001114
db: HMDB

Compound/PW C000660/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pentadecanoic acid
stoichiometric coefficient: 1.0

Reference/UniProt P40308
type: UnificationXref
id: P40308
db: UniProt

PA(15:0/18:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0114814
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
chemical formula: C36H71O8P
molecular weight: 662.48865
structure: ChemicalStructure/PW C062231

Reference/ChemSpider 5902
type: UnificationXref
id: 5902
db: ChemSpider

Reference/ChEBI CHEBI 15541
type: UnificationXref
id: CHEBI:15541
db: ChEBI

Reference/UniProt P33333
type: UnificationXref
id: P33333
db: UniProt

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Pentadecanoyl-CoA
type: SmallMolecule
entity reference: Pentadecanoyl-CoA

Reference/HMDB HMDB0000826
type: UnificationXref
id: HMDB0000826
db: HMDB

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/HMDB HMDB0000827
type: UnificationXref
id: HMDB0000827
db: HMDB

DG(15:0/18:0/0:0)
type: SmallMoleculeReference
xref: Reference/PubChem-compound 14275365
xref: Reference/BioCyc DIACYLGLYCEROL
xref: Reference/HMDB HMDB0007071
xref: Reference/KEGG Compound C00165
xref: Reference/ChemSpider 24765904
chemical formula: C36H70O5
molecular weight: 582.52234
structure: ChemicalStructure/PW C003122

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Pentadecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 74574
xref: Reference/BioCyc CPD-14724
xref: Reference/PubChem-compound 71581247
xref: Reference/HMDB HMDB0062518
chemical formula: C36H64N7O17P3S
molecular weight: 991.3292
structure: ChemicalStructure/PW C062921

CDP
type: SmallMoleculeReference
xref: Reference/ChemSpider 5902
xref: Reference/PubChem-compound 6132
xref: Reference/HMDB HMDB0001546
xref: Reference/ChEBI CHEBI 17239
xref: Reference/BioCyc CDP
xref: Reference/CAS 63-38-7
xref: Reference/KEGG Compound C00112
chemical formula: C9H15N3O11P2
molecular weight: 403.0182
structure: ChemicalStructure/PW C001189

MG(16:0/0:0/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 75542
xref: Reference/ChemSpider 2341519
xref: Reference/CAS 32899-41-5
xref: Reference/HMDB HMDB0011564
xref: Reference/PubChem-compound 3084463
chemical formula: C19H38O4
molecular weight: 330.277
structure: ChemicalStructure/PW C007160

Reference/UniProt P36165
type: UnificationXref
id: P36165
db: UniProt

Reference/PubChem-compound 3084463
type: UnificationXref
id: 3084463
db: PubChem-compound

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Monoglyceride lipase
type: Protein
entity reference: Monoglyceride lipase

Reference/HMDB HMDB0114814
type: UnificationXref
id: HMDB0114814
db: HMDB

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

Stearic acid
type: SmallMolecule
entity reference: Stearic acid

Reference/SMPDB SMP0006934
type: UnificationXref
id: SMP0006934
db: SMPDB

Pentadecanoic acid
type: SmallMolecule
entity reference: Pentadecanoic acid

Reference/PubChem-compound 13849
type: UnificationXref
id: 13849
db: PubChem-compound

Stearic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 28842
xref: Reference/PubChem-compound 5281
xref: Reference/ChemSpider 5091
xref: Reference/KEGG Compound C01530
xref: Reference/BioCyc STEARIC ACID
xref: Reference/HMDB HMDB0000827
xref: Reference/CAS 57-11-4
chemical formula: C18H36O2
molecular weight: 284.27155
structure: ChemicalStructure/PW C000661

TG(15:0/18:0/18:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0043049
chemical formula: C54H104O6
molecular weight: 848.78326
structure: ChemicalStructure/PW C023762

Pentadecanoic acid
type: SmallMoleculeReference
xref: Reference/CAS 1002-84-2
xref: Reference/PubChem-compound 13849
xref: Reference/ChEBI CHEBI 42504
xref: Reference/HMDB HMDB0000826
xref: Reference/KEGG Compound C16537
xref: Reference/ChemSpider 13249
chemical formula: C15H30O2
molecular weight: 242.22458
structure: ChemicalStructure/PW C000660

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Lipase 3
type: Protein
entity reference: Lipase 3

Lipase 4
type: Protein
entity reference: Lipase 4

ChemicalStructure/PW C007160
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@](O)(CO)COC(=O)CCCCCCCCCCCCCCC

Lipase 5
type: Protein
entity reference: Lipase 5

2.3.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000871/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062231/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055364/Stoichiometry/1.0
right: PA(15:0/18:0)
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.23
left: Stearoyl-CoA
left: LysoPA(15:0/0:0)
name: LysoPA(15:0/0:0) + Stearoyl-CoA → Coenzyme A + PA(15:0/18:0)
conversion direction: LEFT_TO_RIGHT

Diacylglycerol O-acyltransferase 1
type: Protein
entity reference: Diacylglycerol O-acyltransferase 1

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/UniProt Q12382
type: UnificationXref
id: Q12382
db: UniProt

Reference/UniProt P32784
type: UnificationXref
id: P32784
db: UniProt

Sterol esterase TGL1
type: Protein
entity reference: Sterol esterase TGL1

Lipase 2
type: Protein
entity reference: Lipase 2

3.1.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000661/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007160/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003122/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Stearic acid
right: Hydrogen Ion
right: MG(16:0/0:0/0:0)
spontaneous: false
EC number: 3.1.1.3
left: Water
left: DG(15:0/18:0/0:0)
name: DG(15:0/18:0/0:0) + Water → Hydrogen Ion + MG(16:0/0:0/0:0) + Stearic acid
conversion direction: LEFT_TO_RIGHT

3.1.1.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000661/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C023762/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003122/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Stearic acid
right: Hydrogen Ion
right: DG(15:0/18:0/0:0)
spontaneous: false
EC number: 3.1.1.13
left: Water
left: TG(15:0/18:0/18:0)
name: TG(15:0/18:0/18:0) + Water → DG(15:0/18:0/0:0) + Hydrogen Ion + Stearic acid
conversion direction: LEFT_TO_RIGHT

2.3.1.20
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000871/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C023762/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003122/Stoichiometry/1.0
right: Coenzyme A
right: TG(15:0/18:0/18:0)
spontaneous: false
EC number: 2.3.1.20
left: Stearoyl-CoA
left: DG(15:0/18:0/0:0)
name: DG(15:0/18:0/0:0) + Stearoyl-CoA → Coenzyme A + TG(15:0/18:0/18:0)
conversion direction: LEFT_TO_RIGHT

Phosphate
type: SmallMolecule
entity reference: Phosphate

2.7.1.174
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062231/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003122/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189/Stoichiometry/1.0
right: PA(15:0/18:0)
right: CDP
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.1.174
left: Cytidine triphosphate
left: DG(15:0/18:0/0:0)
name: Cytidine triphosphate + DG(15:0/18:0/0:0) → CDP + Hydrogen Ion + PA(15:0/18:0)
conversion direction: LEFT_TO_RIGHT

3.1.3.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062231/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003122/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: DG(15:0/18:0/0:0)
right: Phosphate
spontaneous: false
EC number: 3.1.3.4
left: PA(15:0/18:0)
left: Water
name: PA(15:0/18:0) + Water → DG(15:0/18:0/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 733
type: UnificationXref
id: 733
db: ChemSpider

Reference/PubChem-compound 14275365
type: UnificationXref
id: 14275365
db: PubChem-compound

ReactionCatalysis201060
type: Catalysis
controller: Lipase 3
controlled: 3.1.1.3
control type: ACTIVATION

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ReactionCatalysis201061
type: Catalysis
controller: Monoglyceride lipase
controlled: 3.1.1.23
control type: ACTIVATION

ChemicalStructure/PW C003122
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001189
type: ChemicalStructure
structure format: SMILES

Compound/PW C055364/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPA(15:0/0:0)
stoichiometric coefficient: 1.0

Reference/KEGG Compound C16537
type: UnificationXref
id: C16537
db: KEGG Compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/CAS 57-11-4
type: UnificationXref
id: 57-11-4
db: CAS

Reference/UniProt P34163
type: UnificationXref
id: P34163
db: UniProt

PA(15:0/18:0)
type: SmallMolecule
entity reference: PA(15:0/18:0)

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

3.1.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007160/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000660/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000085/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Glycerol
right: Pentadecanoic acid
right: Hydrogen Ion
spontaneous: false
EC number: 3.1.1.23
left: Water
left: MG(16:0/0:0/0:0)
name: MG(16:0/0:0/0:0) + Water → Glycerol + Hydrogen Ion + Pentadecanoic acid
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000660
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCC(O)=O

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

ChemicalStructure/PW C023762
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

ChemicalStructure/PW C000661
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCCCC(O)=O

Compound/PW C000085/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol
stoichiometric coefficient: 1.0

Reference/PubChem-compound 439229
type: UnificationXref
id: 439229
db: PubChem-compound

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/CAS 362-66-3
type: UnificationXref
id: 362-66-3
db: CAS

Reference/UniProt P32567
type: UnificationXref
id: P32567
db: UniProt

Reference/ChEBI CHEBI 17522
type: UnificationXref
id: CHEBI:17522
db: ChEBI

Reference/TAXONOMY 4932
type: UnificationXref
id: 4932
db: TAXONOMY

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

Reference/PathWhiz PW007792
type: UnificationXref
id: PW007792
db: PathWhiz

Reference/KEGG Compound C00412
type: UnificationXref
id: C00412
db: KEGG Compound

LysoPA(15:0/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16975
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
chemical formula: C18H37O7P
molecular weight: 396.2277
structure: ChemicalStructure/PW C055364

Reference/UniProt Q08548
type: UnificationXref
id: Q08548
db: UniProt

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C000871
type: ChemicalStructure
structure format: SMILES

CTP-dependent diacylglycerol kinase 1
type: ProteinReference
xref: Reference/UniProt Q12382

Phosphatidic acid phosphohydrolase 1
type: ProteinReference
xref: Reference/UniProt P32567

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

2.3.1.15
type: BiochemicalReaction
participant stoichiometry: Compound/PW C062921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055364/Stoichiometry/1.0
right: Coenzyme A
right: LysoPA(15:0/0:0)
spontaneous: false
EC number: 2.3.1.15
left: Pentadecanoyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Pentadecanoyl-CoA → Coenzyme A + LysoPA(15:0/0:0)
conversion direction: LEFT_TO_RIGHT

Compound/PW C062921/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pentadecanoyl-CoA
stoichiometric coefficient: 1.0

Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
type: Protein
entity reference: Lysophosphatidic acid:oleoyl-CoA acyltransferase 1

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

Lysophosphatidate acyltransferase
type: Complex
component: Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
component: Acyl-CoA:lyso-phospholipid acyltransferase
component: Lipase 4
component: Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
component: Lipase 5

Acyl-CoA:lyso-phospholipid acyltransferase
type: Protein
entity reference: Acyl-CoA:lyso-phospholipid acyltransferase

Lipase 4
type: Protein
entity reference: Lipase 4

ReactionCatalysis201058
type: Catalysis
controller: Diacylglycerol O-acyltransferase 1
controlled: 2.3.1.20
control type: ACTIVATION

Glycerol-3-phosphate O-acyltransferase
type: Complex
component: Glycerol-3-phosphate O-acyltransferase 2
component: Glycerol-3-phosphate O-acyltransferase 1

LysoPA(15:0/0:0)
type: SmallMolecule
entity reference: LysoPA(15:0/0:0)

Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
type: Protein
entity reference: Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase

ReactionCatalysis201059
type: Catalysis
controller: Triacylglycerol lipase complex
controlled: 3.1.1.13
control type: ACTIVATION

Lipase 5
type: Protein
entity reference: Lipase 5

ChemicalStructure/PW C000085
type: ChemicalStructure
structure format: SMILES
structure data: OCC(O)CO

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/HMDB HMDB0062518
type: UnificationXref
id: HMDB0062518
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Lipase 3
type: ProteinReference
xref: Reference/UniProt P40308

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O