1.1.1.316
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C014766 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C059075 Cytosol/Stoichiometry/1.0
right: Hydrogen Ion
right: L-galactono-1,4-lactone
right: NADH
spontaneous: false
EC number: 1.1.1.316
left: NAD
left: L-Galactose
name: L-Galactose + NAD → Hydrogen Ion + L-galactono-1,4-lactone + NADH
conversion direction: LEFT_TO_RIGHT

1.3.2.3
type: BiochemicalReaction
participant stoichiometry: Protein/Generic17 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Protein/Generic16 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C059075 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000031 Mitochondrial Matrix/Stoichiometry/1.0
right: Ferrocytochrome c
right: Ascorbic acid
right: Hydrogen Ion
spontaneous: false
EC number: 1.3.2.3
left: Ferricytochrome c
left: L-galactono-1,4-lactone
name: 2 Ferricytochrome c + L-galactono-1,4-lactone → Ascorbic acid + 2 Ferrocytochrome c + 2 Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Reference/CAS 7722-84-1
type: UnificationXref
id: 7722-84-1
db: CAS

Reference/UniProt Q93VR3
type: UnificationXref
id: Q93VR3
db: UniProt

Reference/TAXONOMY 3702
type: UnificationXref
id: 3702
db: TAXONOMY

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

GDP-mannose 3,5-epimerase
type: Protein
cellular location: Cytosol
entity reference: GDP-mannose 3,5-epimerase

Reference/ChEBI CHEBI 17464
type: UnificationXref
id: CHEBI:17464
db: ChEBI

Reference/KEGG Compound C15926
type: UnificationXref
id: C15926
db: KEGG Compound

Reference/KEGG Compound C15925
type: UnificationXref
id: C15925
db: KEGG Compound

Reference/HMDB HMDB0003125
type: UnificationXref
id: HMDB0003125
db: HMDB

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

ChemicalStructure/PW C001783
type: ChemicalStructure
structure format: SMILES
structure data: OO

Transport911
type: Transport
participant stoichiometry: Compound/PW C059075 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C059075 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: L-galactono-1,4-lactone
spontaneous: false
left: L-galactono-1,4-lactone
name: L-galactono-1,4-lactone (→) Transport: Arabidopsis thaliana, Cell, Mitochondrial Inner Membrane to Arabidopsis thaliana, Cell, Mitochondrial Matrix
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 5483640
type: UnificationXref
id: 5483640
db: PubChem-compound

Ascorbic acid
type: SmallMoleculeReference
xref: Reference/BioCyc ASCORBATE
xref: Reference/ChemSpider 10189562
xref: Reference/KEGG Compound C00072
xref: Reference/ChEBI CHEBI 29073
xref: Reference/CAS 50-81-7
xref: Reference/PubChem-compound 54670067
xref: Reference/HMDB HMDB0000044
chemical formula: C6H8O6
molecular weight: 176.03209
structure: ChemicalStructure/PW C000031

Reference/ChEBI CHEBI 16928
type: UnificationXref
id: CHEBI:16928
db: ChEBI

Reaction48163
type: BiochemicalReaction
participant stoichiometry: Protein/Generic17 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000977 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Protein/Generic16 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000031 Mitochondrial Matrix/Stoichiometry/1.0
right: Dehydroascorbic acid
right: Ferrocytochrome c
right: Hydrogen Ion
spontaneous: false
left: Ferricytochrome c
left: Ascorbic acid
name: Ascorbic acid + 2 Ferricytochrome c → Dehydroascorbic acid + 2 Ferrocytochrome c + 2 Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

1.11.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059077 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001783 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000031 Mitochondrial Matrix/Stoichiometry/2.0
right: Water
right: monodehydroascorbate radical
spontaneous: false
EC number: 1.11.1.11
left: Hydrogen peroxide
left: Ascorbic acid
name: 2 Ascorbic acid + Hydrogen peroxide → 2 Water + 2 monodehydroascorbate radical
conversion direction: LEFT_TO_RIGHT

1.6.5.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059077 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000031 Mitochondrial Matrix/Stoichiometry/2.0
right: NAD
right: Ascorbic acid
spontaneous: false
EC number: 1.6.5.4
left: monodehydroascorbate radical
left: NADH
left: Hydrogen Ion
name: Hydrogen Ion + NADH + 2 monodehydroascorbate radical → 2 Ascorbic acid + NAD
conversion direction: LEFT_TO_RIGHT

Compound/PW C014766 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Galactose
stoichiometric coefficient: 1.0

Amino Sugar and Nucleotide Sugar Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway4854
pathway component: SubPathwayInteraction4854
name: SubPathway

TransportCatalysis809
type: Catalysis
controller: L-galactono-1,4-lactone transporter
controlled: Transport911
control type: ACTIVATION

Reference/ChEBI CHEBI 37619
type: UnificationXref
id: CHEBI:37619
db: ChEBI

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/UniProt O81884
type: UnificationXref
id: O81884
db: UniProt

Reference/ChEBI CHEBI 15820
type: UnificationXref
id: CHEBI:15820
db: ChEBI

Reference/UniProt P92947
type: UnificationXref
id: P92947
db: UniProt

NADH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADH

SubPathwayInteraction4854
type: Interaction
name: SubPathwayReaction
name: SubPathway4854Reaction
participant: Guanosine diphosphate mannose

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Compound/PW C059075 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-galactono-1,4-lactone
stoichiometric coefficient: 1.0

SubPathwayInteraction4853
type: Interaction
name: SubPathway4853Reaction
name: SubPathwayReaction
participant: Guanosine diphosphate mannose

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/ChemSpider 10189562
type: UnificationXref
id: 10189562
db: ChemSpider

Reference/UniProt Q8RWE8
type: UnificationXref
id: Q8RWE8
db: UniProt

L-Galactose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 37619
xref: Reference/HMDB HMDB0033704
xref: Reference/ChemSpider 10175754
xref: Reference/CAS 59-23-4 10257-28-0
xref: Reference/PubChem-compound 12003287
xref: Reference/KEGG Compound C00124
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C014766

L-galactose dehydrogenase
type: Protein
cellular location: Cytosol
entity reference: L-galactose dehydrogenase

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/PubChem-compound 6857365
type: UnificationXref
id: 6857365
db: PubChem-compound

Compound/PW C059073 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: GDP-L-galactose
stoichiometric coefficient: 1.0

Guanosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Guanosine diphosphate

5.1.3.18
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059072 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000901 Cytosol/Stoichiometry/1.0
right: GDP-L-gulose
spontaneous: false
EC number: 5.1.3.18
left: Guanosine diphosphate mannose
name: Guanosine diphosphate mannose ↔ GDP-L-gulose
conversion direction: REVERSIBLE

Reaction48146
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059073 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000901 Cytosol/Stoichiometry/1.0
right: GDP-L-galactose
spontaneous: false
left: Guanosine diphosphate mannose
name: Guanosine diphosphate mannose ↔ GDP-L-galactose
conversion direction: REVERSIBLE

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reaction48147
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059072 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C059073 Cytosol/Stoichiometry/1.0
right: GDP-L-galactose
spontaneous: false
left: GDP-L-gulose
name: GDP-L-gulose ↔ GDP-L-galactose
conversion direction: REVERSIBLE

Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 2.0

2.7.7.69
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059073 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000936 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C059074 Cytosol/Stoichiometry/1.0
right: Guanosine diphosphate
right: L-galactose 1-phosphate
spontaneous: false
EC number: 2.7.7.69
left: Phosphate
left: GDP-L-galactose
name: GDP-L-galactose + Phosphate → Guanosine diphosphate + L-galactose 1-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16240
type: UnificationXref
id: CHEBI:16240
db: ChEBI

3.1.3.93
type: BiochemicalReaction
participant stoichiometry: Compound/PW C014766 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C059074 Cytosol/Stoichiometry/1.0
right: Phosphate
right: L-Galactose
spontaneous: false
EC number: 3.1.3.93
left: L-galactose 1-phosphate
left: Water
name: L-galactose 1-phosphate + Water → L-Galactose + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Guanosine diphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001201
xref: Reference/BioCyc GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE
xref: Reference/CAS 146-91-8
xref: Reference/PubChem-compound 8977
xref: Reference/ChEBI CHEBI 17552
xref: Reference/ChemSpider 8630
xref: Reference/KEGG Compound C00035
chemical formula: C10H15N5O11P2
molecular weight: 443.02432
structure: ChemicalStructure/PW C000936

Compound/PW C059072 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: GDP-L-gulose
stoichiometric coefficient: 1.0

L-galactose 1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: L-galactose 1-phosphate

L-galactose 1-phosphate phosphatase
type: Protein
cellular location: Cytosol
entity reference: L-galactose 1-phosphate phosphatase

L-galactono-1,4-lactone
type: SmallMolecule
cellular location: Cytosol
entity reference: L-galactono-1,4-lactone

Reference/BioCyc CPD-330
type: UnificationXref
id: CPD-330
db: BioCyc

ReactionCatalysis38292
type: Catalysis
controller: monodehydroascorbate reductase 5
controlled: 1.6.5.4
control type: ACTIVATION

ReactionCatalysis38291
type: Catalysis
controller: L-ascorbate peroxidase S
controlled: 1.11.1.11
control type: ACTIVATION

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Compound/PW C000031 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ascorbic acid
stoichiometric coefficient: 1.0

Compound/PW C001144 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 2.0

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

ReactionCatalysis38290
type: Catalysis
controller: L-galactono-1,4-lactone dehydrogenase
controlled: Reaction48163
control type: ACTIVATION

Compound/PW C000936 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Guanosine diphosphate
stoichiometric coefficient: 1.0

Reference/BioCyc GDP-MANNOSE
type: UnificationXref
id: GDP-MANNOSE
db: BioCyc

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 16504
type: UnificationXref
id: CHEBI:16504
db: ChEBI

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/CAS 50-81-7
type: UnificationXref
id: 50-81-7
db: CAS

Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000721 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000936
type: ChemicalStructure
structure format: SMILES

NADH
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: NADH

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00124
type: UnificationXref
id: C00124
db: KEGG Compound

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/BioCyc GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE
type: UnificationXref
id: GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE
db: BioCyc

Reference/GENE ONTOLOGY GO 0005759
type: UnificationXref
id: GO:0005759
db: GENE ONTOLOGY

Reference/CAS 1668-08-2
type: UnificationXref
id: 1668-08-2
db: CAS

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

Reference/ChemSpider 182283
type: UnificationXref
id: 182283
db: ChemSpider

L-galactono-1,4-lactone transporter
type: Protein
entity reference: L-galactono-1,4-lactone transporter

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/BioCyc CPD-7078
type: UnificationXref
id: CPD-7078
db: BioCyc

Reference/BioCyc GDP-L-GALACTOSE
type: UnificationXref
id: GDP-L-GALACTOSE
db: BioCyc

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

L-ascorbate peroxidase S
type: Protein
cellular location: Mitochondrial Matrix
entity reference: L-ascorbate peroxidase S

ChemicalStructure/PW C000901
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 17242
type: UnificationXref
id: CHEBI:17242
db: ChEBI

Hydrogen Ion
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Hydrogen Ion

Reference/HMDB HMDB0001201
type: UnificationXref
id: HMDB0001201
db: HMDB

Reference/ChemSpider 17372
type: UnificationXref
id: 17372
db: ChemSpider

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/HMDB HMDB0033704
type: UnificationXref
id: HMDB0033704
db: HMDB

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

Reference/BioCyc CPD-318
type: UnificationXref
id: CPD-318
db: BioCyc

ChemicalStructure/PW C059075
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C059074
type: ChemicalStructure
structure format: SMILES

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Dehydroascorbic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00425
xref: Reference/BioCyc L-DEHYDRO-ASCORBATE
xref: Reference/CAS 490-83-5
xref: Reference/ChemSpider 182283
xref: Reference/PubChem-compound 210328
xref: Reference/ChEBI CHEBI 17242
xref: Reference/HMDB HMDB0001264
chemical formula: C6H6O6
molecular weight: 174.01643
structure: ChemicalStructure/PW C000977

ChemicalStructure/PW C059077
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C014766
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O

ChemicalStructure/PW C059073
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C059072
type: ChemicalStructure
structure format: SMILES

L-galactono-1,4-lactone
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: L-galactono-1,4-lactone

Ferrocytochrome c
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Ferrocytochrome c

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00027
type: UnificationXref
id: C00027
db: KEGG Compound

Reference/KEGG Compound C01115
type: UnificationXref
id: C01115
db: KEGG Compound

Reference/ChEBI CHEBI 15991
type: UnificationXref
id: CHEBI:15991
db: ChEBI

GDP-L-gulose
type: SmallMolecule
cellular location: Cytosol
entity reference: GDP-L-gulose

Reference/PubChem-compound 54670067
type: UnificationXref
id: 54670067
db: PubChem-compound

Reference/ChEBI CHEBI 18038
type: UnificationXref
id: CHEBI:18038
db: ChEBI

Ferricytochrome c
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Ferricytochrome c

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00035
type: UnificationXref
id: C00035
db: KEGG Compound

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Compound/PW C059077 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: monodehydroascorbate radical
stoichiometric coefficient: 2.0

Reference/BioCyc CPDQT-4
type: UnificationXref
id: CPDQT-4
db: BioCyc

L-galactono-1,4-lactone transporter
type: ProteinReference
xref: Reference/UniProt Z0Z000

monodehydroascorbate reductase 5
type: ProteinReference
xref: Reference/UniProt P92947
organism: Arabidopsis thaliana

Reference/BioCyc HYDROGEN-PEROXIDE
type: UnificationXref
id: HYDROGEN-PEROXIDE
db: BioCyc

L-galactose dehydrogenase
type: ProteinReference
xref: Reference/UniProt O81884
organism: Arabidopsis thaliana

Reference/PubChem-compound 210328
type: UnificationXref
id: 210328
db: PubChem-compound

L-galactose 1-phosphate phosphatase
type: ProteinReference
xref: Reference/UniProt Q9M8S8
organism: Arabidopsis thaliana

L-ascorbate peroxidase S
type: ProteinReference
xref: Reference/UniProt Q42592
organism: Arabidopsis thaliana

Mitochondrial Matrix
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005759

L-galactono-1,4-lactone dehydrogenase
type: ProteinReference
xref: Reference/UniProt Q9SU56
organism: Arabidopsis thaliana

GDP-L-galactose phosphorylase 1
type: ProteinReference
xref: Reference/UniProt Q8RWE8
organism: Arabidopsis thaliana

GDP-mannose 3,5-epimerase
type: ProteinReference
xref: Reference/UniProt Q93VR3
organism: Arabidopsis thaliana

GDP-L-gulose
type: SmallMoleculeReference
xref: Reference/KEGG Compound C15925
xref: Reference/PubChem-compound 23724606
xref: Reference/ChEBI CHEBI 80182
xref: Reference/BioCyc CPD-7078
chemical formula: C16H25N5O16P2
molecular weight: 605.07715
structure: ChemicalStructure/PW C059072

Compound/PW C000977 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dehydroascorbic acid
stoichiometric coefficient: 1.0

L-galactono-1,4-lactone
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6857365
xref: Reference/CAS 1668-08-2
xref: Reference/BioCyc CPD-330
xref: Reference/ChEBI CHEBI 17464
xref: Reference/ChemSpider CPD-330
xref: Reference/KEGG Compound C01115
chemical formula: C6H10O6
molecular weight: 178.04774
structure: ChemicalStructure/PW C059075

GDP-L-galactose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18038
xref: Reference/KEGG Compound C02280
xref: Reference/PubChem-compound 439695
xref: Reference/BioCyc GDP-L-GALACTOSE
chemical formula: C16H25N5O16P2
molecular weight: 605.07715
structure: ChemicalStructure/PW C059073

L-Galactose
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Galactose

L-galactose 1-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C15926
xref: Reference/BioCyc CPDQT-4
xref: Reference/ChEBI CHEBI 53072
xref: Reference/PubChem-compound 23724607
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C059074

Reference/PathWhiz PW013309
type: UnificationXref
id: PW013309
db: PathWhiz

monodehydroascorbate radical
type: SmallMoleculeReference
xref: Reference/KEGG Compound C01041
xref: Reference/ChEBI CHEBI 16504
xref: Reference/PubChem-compound 5483640
xref: Reference/BioCyc CPD-318
chemical formula: C6H7O6
molecular weight: 175.02426
structure: ChemicalStructure/PW C059077

Reference/PathWhiz PW013307
type: UnificationXref
id: PW013307
db: PathWhiz

Reference/UniProt Q9M8S8
type: UnificationXref
id: Q9M8S8
db: UniProt

ChemicalStructure/PW C000977
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@]1(OC(=O)C(=O)C1=O)[C@H](O)CO

GDP-L-galactose
type: SmallMolecule
cellular location: Cytosol
entity reference: GDP-L-galactose

Reference/ChemSpider 763
type: UnificationXref
id: 763
db: ChemSpider

Dehydroascorbic acid
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Dehydroascorbic acid

Reference/CAS 59-23-4 10257-28-0
type: UnificationXref
id: 59-23-4 10257-28-0
db: CAS

ReactionCatalysis38278
type: Catalysis
controller: L-galactono-1,4-lactone dehydrogenase
controlled: 1.3.2.3
control type: ACTIVATION

Ferricytochrome c
type: ProteinReference
xref: Reference/ChEBI CHEBI 15991
organism: Arabidopsis thaliana

ReactionCatalysis38277
type: Catalysis
controller: L-galactose dehydrogenase
controlled: 1.1.1.316
control type: ACTIVATION

Reference/PubChem-compound 784
type: UnificationXref
id: 784
db: PubChem-compound

Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ReactionCatalysis38272
type: Catalysis
controller: GDP-mannose 3,5-epimerase
controlled: 5.1.3.18
control type: ACTIVATION

Arabidopsis thaliana
type: BioSource
xref: Reference/TAXONOMY 3702

ReactionCatalysis38274
type: Catalysis
controller: GDP-mannose 3,5-epimerase
controlled: Reaction48147
control type: ACTIVATION

Reference/PubChem-compound 23724607
type: UnificationXref
id: 23724607
db: PubChem-compound

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Compound/PW C000031 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: Ascorbic acid
stoichiometric coefficient: 2.0

ReactionCatalysis38273
type: Catalysis
controller: GDP-mannose 3,5-epimerase
controlled: Reaction48146
control type: ACTIVATION

ReactionCatalysis38276
type: Catalysis
controller: L-galactose 1-phosphate phosphatase
controlled: 3.1.3.93
control type: ACTIVATION

Compound/PW C059075 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-galactono-1,4-lactone
stoichiometric coefficient: 1.0

ReactionCatalysis38275
type: Catalysis
controller: GDP-L-galactose phosphorylase 1
controlled: 2.7.7.69
control type: ACTIVATION

Ferrocytochrome c
type: ProteinReference
xref: Reference/ChEBI CHEBI 16928
organism: Arabidopsis thaliana

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

ChemicalStructure/PW C000031
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)CO

Reference/PubChem-compound 23724606
type: UnificationXref
id: 23724606
db: PubChem-compound

Hydrogen peroxide
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Hydrogen peroxide

Reference/PubChem-compound 439695
type: UnificationXref
id: 439695
db: PubChem-compound

Compound/PW C059074 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-galactose 1-phosphate
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

NAD
type: SmallMolecule
cellular location: Cytosol
entity reference: NAD

Reference/ChEBI CHEBI 53072
type: UnificationXref
id: CHEBI:53072
db: ChEBI

Reference/PubChem-compound 8977
type: UnificationXref
id: 8977
db: PubChem-compound

Ascorbate Metabolism
type: Pathway
pathway order: PathwaySubPathway/4853
pathway order: PathwaySubPathway/4854
pathway order: PathwayEnzymeReaction/229489
pathway order: PathwayEnzymeReaction/229487
pathway order: PathwayEnzymeReaction/229488
pathway order: PathwayEnzymeReaction/229485
pathway order: PathwayEnzymeReaction/229496
pathway order: PathwayEnzymeReaction/229486
pathway order: PathwayEnzymeReaction/229494
pathway order: PathwayEnzymeReaction/229495
pathway order: PathwayTransport/229492
pathway order: PathwayEnzymeReaction/229493
pathway order: PathwayEnzymeReaction/229490
pathway component: ReactionCatalysis38278
pathway component: 1.1.1.316
pathway component: ReactionCatalysis38277
pathway component: 1.3.2.3
pathway component: Reaction48163
pathway component: 1.11.1.11
pathway component: 1.6.5.4
pathway component: 5.1.3.18
pathway component: Reaction48146
pathway component: ReactionCatalysis38292
pathway component: Reaction48147
pathway component: ReactionCatalysis38291
pathway component: ReactionCatalysis38272
pathway component: 2.7.7.69
pathway component: 3.1.3.93
pathway component: ReactionCatalysis38274
pathway component: Amino Sugar and Nucleotide Sugar Metabolism
pathway component: ReactionCatalysis38273
pathway component: ReactionCatalysis38276
pathway component: ReactionCatalysis38275
pathway component: TransportCatalysis809
pathway component: Mannose Metabolism
pathway component: ReactionCatalysis38290
pathway component: Transport911
xref: Reference/SMPDB SMP0012446
xref: Reference/PathWhiz PW013309
organism: Arabidopsis thaliana

NAD
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: NAD

Mannose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway4853
pathway component: SubPathwayInteraction4853
xref: Reference/PathWhiz PW013307
xref: Reference/SMPDB SMP0012444
name: SubPathway

Reference/KEGG Compound C01041
type: UnificationXref
id: C01041
db: KEGG Compound

Reference/KEGG Compound C00072
type: UnificationXref
id: C00072
db: KEGG Compound

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Compound/PW C059075 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-galactono-1,4-lactone
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000044
type: UnificationXref
id: HMDB0000044
db: HMDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Guanosine diphosphate mannose
type: SmallMoleculeReference
xref: Reference/BioCyc GDP-MANNOSE
xref: Reference/CAS 3123-67-9
xref: Reference/KEGG Compound C00096
xref: Reference/PubChem-compound 18396
xref: Reference/ChemSpider 17372
xref: Reference/ChEBI CHEBI 15820
xref: Reference/HMDB HMDB0001163
chemical formula: C16H25N5O16P2
molecular weight: 605.07715
structure: ChemicalStructure/PW C000901

Protein/Generic17 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: Ferricytochrome c
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 80182
type: UnificationXref
id: CHEBI:80182
db: ChEBI

Compound/PW C001783 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen peroxide
stoichiometric coefficient: 1.0

Reference/ChemSpider 8630
type: UnificationXref
id: 8630
db: ChemSpider

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Water
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Water

Reference/UniProt Q9SU56
type: UnificationXref
id: Q9SU56
db: UniProt

Reference/UniProt Q42592
type: UnificationXref
id: Q42592
db: UniProt

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0001264
type: UnificationXref
id: HMDB0001264
db: HMDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

L-galactono-1,4-lactone dehydrogenase
type: Protein
cellular location: Mitochondrial Matrix
entity reference: L-galactono-1,4-lactone dehydrogenase

L-galactono-1,4-lactone
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: L-galactono-1,4-lactone

Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17552
type: UnificationXref
id: CHEBI:17552
db: ChEBI

Reference/PubChem-compound 12003287
type: UnificationXref
id: 12003287
db: PubChem-compound

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Reference/CAS 3123-67-9
type: UnificationXref
id: 3123-67-9
db: CAS

Reference/KEGG Compound C00096
type: UnificationXref
id: C00096
db: KEGG Compound

Reference/BioCyc L-DEHYDRO-ASCORBATE
type: UnificationXref
id: L-DEHYDRO-ASCORBATE
db: BioCyc

Reference/CAS 490-83-5
type: UnificationXref
id: 490-83-5
db: CAS

Ascorbic acid
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Ascorbic acid

Protein/Generic16 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: Ferrocytochrome c
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 29073
type: UnificationXref
id: CHEBI:29073
db: ChEBI

GDP-L-galactose phosphorylase 1
type: Protein
cellular location: Cytosol
entity reference: GDP-L-galactose phosphorylase 1

Reference/PubChem-compound 18396
type: UnificationXref
id: 18396
db: PubChem-compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Hydrogen peroxide
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003125
xref: Reference/PubChem-compound 784
xref: Reference/ChemSpider 763
xref: Reference/CAS 7722-84-1
xref: Reference/BioCyc HYDROGEN-PEROXIDE
xref: Reference/ChEBI CHEBI 16240
xref: Reference/KEGG Compound C00027
chemical formula: H2O2
molecular weight: 34.005478
structure: ChemicalStructure/PW C001783

Reference/KEGG Compound C02280
type: UnificationXref
id: C02280
db: KEGG Compound

Reference/UniProt Z0Z000
type: UnificationXref
id: Z0Z000
db: UniProt

Reference/ChemSpider CPD-330
type: UnificationXref
id: CPD-330
db: ChemSpider

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/HMDB HMDB0001163
type: UnificationXref
id: HMDB0001163
db: HMDB

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/KEGG Compound C00425
type: UnificationXref
id: C00425
db: KEGG Compound

Compound/PW C000901 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Guanosine diphosphate mannose
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/ChemSpider 10175754
type: UnificationXref
id: 10175754
db: ChemSpider

Reference/SMPDB SMP0012444
type: UnificationXref
id: SMP0012444
db: SMPDB

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc ASCORBATE
type: UnificationXref
id: ASCORBATE
db: BioCyc

Reference/SMPDB SMP0012446
type: UnificationXref
id: SMP0012446
db: SMPDB

monodehydroascorbate reductase 5
type: Protein
cellular location: Mitochondrial Matrix
entity reference: monodehydroascorbate reductase 5

Reference/CAS 146-91-8
type: UnificationXref
id: 146-91-8
db: CAS

monodehydroascorbate radical
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: monodehydroascorbate radical

Guanosine diphosphate mannose
type: SmallMolecule
cellular location: Cytosol
entity reference: Guanosine diphosphate mannose
name: SubPathwayOutput