ReactionCatalysis57172
type: Catalysis
controller: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
controlled: Reaction106576
control type: ACTIVATION

Reaction106643
type: BiochemicalReaction
participant stoichiometry: Compound/PW C076445/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C095008/Stoichiometry/1.0
participant stoichiometry: Compound/PW C076311/Stoichiometry/1.0
right: Cytidine monophosphate
right: CL(i-14:0/i-12:0/a-17:0/i-18:0)
spontaneous: false
left: PG(i-14:0/i-12:0)
left: CDP-DG(a-17:0/i-18:0)
name: CDP-DG(a-17:0/i-18:0) + PG(i-14:0/i-12:0) → CL(i-14:0/i-12:0/a-17:0/i-18:0) + Cytidine monophosphate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis57170
type: Catalysis
controller: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
controlled: 2.7.8.5
control type: ACTIVATION

Phosphatidate cytidylyltransferase 2
type: ProteinReference
xref: Reference/UniProt O95674

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

ReactionCatalysis57179
type: Catalysis
controller: Cardiolipin synthase
controlled: Reaction106643
control type: ACTIVATION

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL-P
db: BioCyc

NADH
type: SmallMolecule
entity reference: NADH

Reference/PathWhiz PW062665
type: UnificationXref
id: PW062665
db: PathWhiz

Reference/UniProt Q9NUQ2
type: UnificationXref
id: Q9NUQ2
db: UniProt

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0112242
type: UnificationXref
id: HMDB0112242
db: HMDB

Reference/HMDB HMDB0112244
type: UnificationXref
id: HMDB0112244
db: HMDB

Compound/PW C063866/Stoichiometry/1.0
type: Stoichiometry
physical entity: Isotetradecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

SubPathwayInteraction55269
type: Interaction
name: SubPathway55269Reaction
name: SubPathwayReaction
participant: Dihydroxyacetone phosphate

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

ChemicalStructure/PW C064200
type: ChemicalStructure
structure format: SMILES

LPA(i-14:0/0:0)
type: SmallMolecule
entity reference: LPA(i-14:0/0:0)

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Compound/PW C000064/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

Compound/PW C076445/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(a-17:0/i-18:0)
stoichiometric coefficient: 1.0

NAD
type: SmallMolecule
entity reference: NAD

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Compound/PW C063865/Stoichiometry/1.0
type: Stoichiometry
physical entity: Isododecanoyl-CoA
stoichiometric coefficient: 1.0

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway55269
pathway component: SubPathwayInteraction55269
xref: Reference/SMPDB SMP0000040
xref: Reference/PathWhiz PW000146
name: SubPathway

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

ChemicalStructure/PW C076529
type: ChemicalStructure
structure format: SMILES

Compound/PW C095008/Stoichiometry/1.0
type: Stoichiometry
physical entity: CL(i-14:0/i-12:0/a-17:0/i-18:0)
stoichiometric coefficient: 1.0

Reaction55814
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: NADH
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH → Glycerol 3-phosphate + NAD
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

PGP(i-14:0/i-12:0)
type: SmallMolecule
entity reference: PGP(i-14:0/i-12:0)

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Cardiolipin synthase
type: Protein
entity reference: Cardiolipin synthase

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
type: Protein
entity reference: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

Reference/HMDB HMDB0114765
type: UnificationXref
id: HMDB0114765
db: HMDB

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

ReactionCatalysis57162
type: Catalysis
controller: 1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon
controlled: Reaction106573
control type: ACTIVATION

Isododecanoyl-CoA
type: SmallMolecule
entity reference: Isododecanoyl-CoA

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

Isotetradecanoyl-CoA
type: SmallMolecule
entity reference: Isotetradecanoyl-CoA

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ReactionCatalysis57167
type: Catalysis
controller: Phosphatidate cytidylyltransferase 2
controlled: 2.7.7.41
control type: ACTIVATION

Reference/KEGG Compound C00344
type: UnificationXref
id: C00344
db: KEGG Compound

Reference/BioCyc CARDIOLIPIN
type: UnificationXref
id: CARDIOLIPIN
db: BioCyc

ChemicalStructure/PW C076311
type: ChemicalStructure
structure format: SMILES

PGP(i-14:0/i-12:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 37393
xref: Reference/HMDB HMDB0116569
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
xref: Reference/KEGG Compound C03892
chemical formula: C32H64O13P2
molecular weight: 718.3822
structure: ChemicalStructure/PW C076374

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Isotetradecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0112244
chemical formula: C35H62N7O17P3S
molecular weight: 977.3136
structure: ChemicalStructure/PW C063866

Isododecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0112242
chemical formula: C33H58N7O17P3S
molecular weight: 949.2823
structure: ChemicalStructure/PW C063865

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

Reference/ChEBI CHEBI 16975
type: UnificationXref
id: CHEBI:16975
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Protein/782/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
stoichiometric coefficient: 2.0

PG(i-14:0/i-12:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17517
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
xref: Reference/HMDB HMDB0116693
xref: Reference/KEGG Compound C00344
chemical formula: C32H63O10P
molecular weight: 638.4159
structure: ChemicalStructure/PW C076311

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Glycerol-3-phosphate acyltransferase 1, mitochondrial
type: Protein
entity reference: Glycerol-3-phosphate acyltransferase 1, mitochondrial

Reference/SMPDB SMP0000040
type: UnificationXref
id: SMP0000040
db: SMPDB

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

PA(i-14:0/i-12:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/HMDB HMDB0115814
xref: Reference/ChEBI CHEBI 16337
chemical formula: C29H57O8P
molecular weight: 564.3791
structure: ChemicalStructure/PW C064200

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/UniProt Q9HCL2
type: UnificationXref
id: Q9HCL2
db: UniProt

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Reference/HMDB HMDB0115814
type: UnificationXref
id: HMDB0115814
db: HMDB

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/HMDB HMDB0116109
type: UnificationXref
id: HMDB0116109
db: HMDB

Cardiolipin Biosynthesis CL(i-14:0/i-12:0/a-17:0/i-18:0)
type: Pathway
pathway order: PathwayEnzymeReaction/1150617
pathway order: PathwayEnzymeReaction/1150616
pathway order: PathwaySubPathway/55269
pathway order: PathwayEnzymeReaction/1150619
pathway order: PathwayEnzymeReaction/1150618
pathway order: PathwayEnzymeReaction/1150620
pathway order: PathwayEnzymeReaction/1150622
pathway order: PathwayEnzymeReaction/1150621
pathway component: ReactionCatalysis57172
pathway component: Reaction106643
pathway component: ReactionCatalysis57162
pathway component: Reaction106576
pathway component: 2.7.8.5
pathway component: 2.7.7.41
pathway component: Reaction106573
pathway component: ReactionCatalysis57170
pathway component: ReactionCatalysis57179
pathway component: Reaction105748
pathway component: ReactionCatalysis57167
pathway component: ReactionCatalysis45939
pathway component: Glycolysis
pathway component: Reaction55814
pathway component: ReactionCatalysis45940
xref: Reference/SMPDB SMP0061713
xref: Reference/PathWhiz PW062665
organism: Homo sapiens

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL
db: BioCyc

Reaction105748
type: BiochemicalReaction
participant stoichiometry: Compound/PW C063883/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C063866/Stoichiometry/1.0
right: Coenzyme A
right: LPA(i-14:0/0:0)
spontaneous: false
left: Isotetradecanoyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Isotetradecanoyl-CoA → Coenzyme A + LPA(i-14:0/0:0)
conversion direction: LEFT_TO_RIGHT

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

ChemicalStructure/PW C095008
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00269
type: UnificationXref
id: C00269
db: KEGG Compound

Compound/PW C076529/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(i-14:0/i-12:0)
stoichiometric coefficient: 1.0

Reference/KEGG Compound C03892
type: UnificationXref
id: C03892
db: KEGG Compound

Cardiolipin synthase
type: ProteinReference
xref: Reference/UniProt Q9UJA2

ReactionCatalysis45939
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
controlled: Reaction55814
control type: ACTIVATION

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q32NB8

CDP-DG(a-17:0/i-18:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17962
xref: Reference/HMDB HMDB0116109
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/KEGG Compound C00269
chemical formula: C47H87N3O15P2
molecular weight: 995.5612
structure: ChemicalStructure/PW C076445

Cytidine monophosphate
type: SmallMolecule
entity reference: Cytidine monophosphate

Reference/UniProt Q9UJA2
type: UnificationXref
id: Q9UJA2
db: UniProt

CDP-DG(a-17:0/i-18:0)
type: SmallMolecule
entity reference: CDP-DG(a-17:0/i-18:0)

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

ReactionCatalysis45940
type: Catalysis
controller: Glycerol-3-phosphate acyltransferase 1, mitochondrial
controlled: Reaction105748
control type: ACTIVATION

Reference/ChEBI CHEBI 28494
type: UnificationXref
id: CHEBI:28494
db: ChEBI

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

PA(i-14:0/i-12:0)
type: SmallMolecule
entity reference: PA(i-14:0/i-12:0)

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C063865
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C063866
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/UniProt Q32NB8
type: UnificationXref
id: Q32NB8
db: UniProt

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Glycerol-3-phosphate acyltransferase 1, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q9HCL2

PG(i-14:0/i-12:0)
type: SmallMolecule
entity reference: PG(i-14:0/i-12:0)

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: ProteinReference
xref: Reference/UniProt P21695

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Reference/UniProt P21695
type: UnificationXref
id: P21695
db: UniProt

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0116569
type: UnificationXref
id: HMDB0116569
db: HMDB

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/ChEBI CHEBI 17517
type: UnificationXref
id: CHEBI:17517
db: ChEBI

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

ChemicalStructure/PW C076374
type: ChemicalStructure
structure format: SMILES

Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
type: Protein
entity reference: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C05980
type: UnificationXref
id: C05980
db: KEGG Compound

1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon
type: Protein
entity reference: 1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon

Reference/UniProt Q8WUK0
type: UnificationXref
id: Q8WUK0
db: UniProt

Reference/HMDB HMDB0116693
type: UnificationXref
id: HMDB0116693
db: HMDB

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

ChemicalStructure/PW C063883
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)CCCCCCCCCCC(=O)OCC(O)COP(O)(O)=O

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Reference/ChEBI CHEBI 17962
type: UnificationXref
id: CHEBI:17962
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Homo sapiens
type: BioSource
xref: Reference/TAXONOMY 9606

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Reference/BioCyc CDPDIACYLGLYCEROL
type: UnificationXref
id: CDPDIACYLGLYCEROL
db: BioCyc

Compound/PW C076311/Stoichiometry/1.0
type: Stoichiometry
physical entity: PG(i-14:0/i-12:0)
stoichiometric coefficient: 1.0

CDP-DG(i-14:0/i-12:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0116193
xref: Reference/ChEBI CHEBI 17962
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/KEGG Compound C00269
chemical formula: C38H69N3O15P2
molecular weight: 869.4204
structure: ChemicalStructure/PW C076529

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

CDP-DG(i-14:0/i-12:0)
type: SmallMolecule
entity reference: CDP-DG(i-14:0/i-12:0)

Reference/TAXONOMY 9606
type: UnificationXref
id: 9606
db: TAXONOMY

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/UniProt O95674
type: UnificationXref
id: O95674
db: UniProt

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/ChEBI CHEBI 37393
type: UnificationXref
id: CHEBI:37393
db: ChEBI

Reference/PathWhiz PW000146
type: UnificationXref
id: PW000146
db: PathWhiz

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/HMDB HMDB0075730
type: UnificationXref
id: HMDB0075730
db: HMDB

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Phosphatidate cytidylyltransferase 2
type: Protein
entity reference: Phosphatidate cytidylyltransferase 2

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

CL(i-14:0/i-12:0/a-17:0/i-18:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0075730
xref: Reference/KEGG Compound C05980
xref: Reference/ChEBI CHEBI 28494
xref: Reference/BioCyc CARDIOLIPIN
chemical formula: C70H136O17P2
molecular weight: 1310.9253
structure: ChemicalStructure/PW C095008

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Compound/PW C076374/Stoichiometry/1.0
type: Stoichiometry
physical entity: PGP(i-14:0/i-12:0)
stoichiometric coefficient: 1.0

Reaction106576
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C076374/Stoichiometry/1.0
participant stoichiometry: Compound/PW C076311/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: PG(i-14:0/i-12:0)
right: Phosphate
spontaneous: false
left: Water
left: PGP(i-14:0/i-12:0)
name: PGP(i-14:0/i-12:0) + Water → PG(i-14:0/i-12:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

2.7.8.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C076374/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C076529/Stoichiometry/1.0
right: Cytidine monophosphate
right: PGP(i-14:0/i-12:0)
spontaneous: false
EC number: 2.7.8.5
left: CDP-DG(i-14:0/i-12:0)
left: Glycerol 3-phosphate
name: CDP-DG(i-14:0/i-12:0) + Glycerol 3-phosphate → Cytidine monophosphate + PGP(i-14:0/i-12:0)
conversion direction: LEFT_TO_RIGHT

2.7.7.41
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C064200/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C076529/Stoichiometry/1.0
right: CDP-DG(i-14:0/i-12:0)
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.41
left: PA(i-14:0/i-12:0)
left: Cytidine triphosphate
name: Cytidine triphosphate + PA(i-14:0/i-12:0) → CDP-DG(i-14:0/i-12:0) + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reaction106573
type: BiochemicalReaction
participant stoichiometry: Compound/PW C063883/Stoichiometry/1.0
participant stoichiometry: Compound/PW C064200/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C063865/Stoichiometry/1.0
right: Coenzyme A
right: PA(i-14:0/i-12:0)
spontaneous: false
left: LPA(i-14:0/0:0)
left: Isododecanoyl-CoA
name: Isododecanoyl-CoA + LPA(i-14:0/0:0) → Coenzyme A + PA(i-14:0/i-12:0)
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

ChemicalStructure/PW C076445
type: ChemicalStructure
structure format: SMILES

Reference/SMPDB SMP0061713
type: UnificationXref
id: SMP0061713
db: SMPDB

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

LPA(i-14:0/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16975
xref: Reference/HMDB HMDB0114765
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
chemical formula: C17H35O7P
molecular weight: 382.21204
structure: ChemicalStructure/PW C063883

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
type: ProteinReference
xref: Reference/UniProt Q8WUK0

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

CL(i-14:0/i-12:0/a-17:0/i-18:0)
type: SmallMolecule
entity reference: CL(i-14:0/i-12:0/a-17:0/i-18:0)

1-Acyl-sn-glycerol-3-phosphate acyltransferase epsilon
type: ProteinReference
xref: Reference/UniProt Q9NUQ2

Compound/PW C063883/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(i-14:0/0:0)
stoichiometric coefficient: 1.0

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Complex
component stoichiometry: Protein/782/Stoichiometry/2.0
component: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Compound/PW C064200/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(i-14:0/i-12:0)
stoichiometric coefficient: 1.0

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0116193
type: UnificationXref
id: HMDB0116193
db: HMDB

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O