Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/ChemSpider 17220838
type: UnificationXref
id: 17220838
db: ChemSpider

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Dodecanoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Dodecanoic acid
name: SubPathwayOutput

(2E)-Decenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: (2E)-Decenoyl-CoA

3-Oxodecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: 3-Oxodecanoyl-CoA

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Compound/PW C002012 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Decenoyl-CoA
stoichiometric coefficient: 1.0

Lauroyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc LAUROYLCOA-CPD
xref: Reference/KEGG Compound C01832
xref: Reference/ChEBI CHEBI 15521
xref: Reference/HMDB HMDB0003571
xref: Reference/CAS 6244-92-4
xref: Reference/ChemSpider 145018
xref: Reference/PubChem-compound 165436
chemical formula: C33H56N7O17P3S
molecular weight: 947.2666
structure: ChemicalStructure/PW C001928

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

Decanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Decanoyl-CoA

Hexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Hexanoyl-CoA
name: SubPathwayInput

Reference/HMDB HMDB0001070
type: UnificationXref
id: HMDB0001070
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/PathWhiz PW000173
type: UnificationXref
id: PW000173
db: PathWhiz

Reference/PathWhiz PW000171
type: UnificationXref
id: PW000171
db: PathWhiz

Reference/UniProt P45952
type: UnificationXref
id: P45952
db: UniProt

TransportCatalysis929
type: Catalysis
controller: Solute carrier family 25 member 44
controlled: Transport1049
control type: ACTIVATION

Reference/HMDB HMDB0006404
type: UnificationXref
id: HMDB0006404
db: HMDB

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/PathWhiz PW064618
type: UnificationXref
id: PW064618
db: PathWhiz

Compound/PW C001928 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lauroyl-CoA
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000167
type: UnificationXref
id: PW000167
db: PathWhiz

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/BioCyc CPD-196
type: UnificationXref
id: CPD-196
db: BioCyc

3-ketoacyl-CoA thiolase, mitochondrial
type: Protein
cellular location: Mitochondrial Matrix
entity reference: 3-ketoacyl-CoA thiolase, mitochondrial

ReactionCatalysis99950
type: Catalysis
controller: 3-ketoacyl-CoA thiolase, mitochondrial
controlled: 2.3.1.16
control type: ACTIVATION

Lauroyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Lauroyl-CoA

Protein/13914 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
stoichiometric coefficient: 2.0

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

Reference/BioCyc 7-METHYL-3-OXOOCTANOYL-COA
type: UnificationXref
id: 7-METHYL-3-OXOOCTANOYL-COA
db: BioCyc

ReactionCatalysis99957
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: 2.3.1.16
control type: ACTIVATION

ReactionCatalysis99956
type: Catalysis
controller: 3-ketoacyl-CoA thiolase, mitochondrial
controlled: 2.3.1.16
control type: ACTIVATION

ReactionCatalysis99953
type: Catalysis
controller: 3-ketoacyl-CoA thiolase, mitochondrial
controlled: 2.3.1.16
control type: ACTIVATION

ReactionCatalysis99954
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: 2.3.1.16
control type: ACTIVATION

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ReactionCatalysis99951
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: 2.3.1.16
control type: ACTIVATION

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

(2E)-Octenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: (2E)-Octenoyl-CoA

Mus musculus
type: BioSource
xref: Reference/TAXONOMY 10090

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
type: Complex
component stoichiometry: Protein/13914 Mitochondrial Matrix/Stoichiometry/2.0
cellular location: Mitochondrial Matrix
component: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

(2E)-Dodecenoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 1066-12-2
xref: Reference/PubChem-compound 45266564
xref: Reference/ChemSpider 26330706
xref: Reference/HMDB HMDB0003712
xref: Reference/BioCyc CPD-7222
xref: Reference/ChEBI CHEBI 57330
xref: Reference/KEGG Compound C03221
chemical formula: C33H56N7O17P3S
molecular weight: 947.2666
structure: ChemicalStructure/PW C001959

Hexanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0002845
xref: Reference/KEGG Compound C05270
xref: Reference/ChemSpider 395736
xref: Reference/CAS 5060-32-2
xref: Reference/PubChem-compound 449118
xref: Reference/ChEBI CHEBI 27540
chemical formula: C27H46N7O17P3S
molecular weight: 865.18835
structure: ChemicalStructure/PW C001719

ReactionCatalysis99847
type: Catalysis
controller: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
controlled: Reaction109620
control type: ACTIVATION

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/ChEBI CHEBI 5086
type: UnificationXref
id: CHEBI:5086
db: ChEBI

Reference/BioCyc LAUROYLCOA-CPD
type: UnificationXref
id: LAUROYLCOA-CPD
db: BioCyc

ReactionCatalysis99850
type: Catalysis
controller: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
controlled: Reaction109622
control type: ACTIVATION

Lauroyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Lauroyl-CoA
name: SubPathwayOutput

Adenosine monophosphate
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Adenosine monophosphate

Compound/Generic70 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Reduced electron-transfer flavoprotein
stoichiometric coefficient: 1.0

Hexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Hexanoyl-CoA

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002742 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002742 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002001 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002001 Mitochondrial Matrix/Stoichiometry/1.0
right: Coenzyme A
right: 3-Oxododecanoyl-CoA
spontaneous: false
EC number: 2.3.1.16
left: Acetyl-CoA
left: Decanoyl-CoA
name: Acetyl-CoA + Decanoyl-CoA → 3-Oxododecanoyl-CoA + Coenzyme A
conversion direction: LEFT_TO_RIGHT

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q61425
organism: Mus musculus

Reference/PubChem-compound 53477508
type: UnificationXref
id: 53477508
db: PubChem-compound

Trifunctional enzyme subunit alpha, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q8BMS1
organism: Mus musculus

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000845 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000845 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002003 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002003 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
right: 3-Oxodecanoyl-CoA
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.16
left: Acetyl-CoA
left: Octanoyl-CoA
name: Acetyl-CoA + Octanoyl-CoA ↔ 3-Oxodecanoyl-CoA + Coenzyme A
conversion direction: REVERSIBLE

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001719 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002005 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002005 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001719 Mitochondrial Matrix/Stoichiometry/1.0
right: 3-Oxooctanoyl-CoA
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.16
left: Acetyl-CoA
left: Hexanoyl-CoA
name: Acetyl-CoA + Hexanoyl-CoA ↔ 3-Oxooctanoyl-CoA + Coenzyme A
conversion direction: REVERSIBLE

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

NADH
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: NADH

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Solute carrier family 25 member 44
type: Protein
entity reference: Solute carrier family 25 member 44

Pyrophosphate
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Pyrophosphate

Coenzyme A
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Coenzyme A

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

3-ketoacyl-CoA thiolase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q8BWT1
organism: Mus musculus

Compound/PW C002013 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Octenoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 389502
type: UnificationXref
id: 389502
db: ChemSpider

Reference/ChemSpider 389501
type: UnificationXref
id: 389501
db: ChemSpider

Octanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C01944
xref: Reference/ChEBI CHEBI 15533
xref: Reference/HMDB HMDB0001070
xref: Reference/ChemSpider 371
xref: Reference/BioCyc CPD-196
xref: Reference/PubChem-compound 380
xref: Reference/CAS 1264-52-4
chemical formula: C29H50N7O17P3S
molecular weight: 893.21967
structure: ChemicalStructure/PW C000845

Reference/KEGG Compound C02679
type: UnificationXref
id: C02679
db: KEGG Compound

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/ChemSpider 389506
type: UnificationXref
id: 389506
db: ChemSpider

Reference/ChemSpider 389504
type: UnificationXref
id: 389504
db: ChemSpider

ReactionCatalysis99869
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction109632
control type: ACTIVATION

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

ReactionCatalysis99868
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: Reaction109632
control type: ACTIVATION

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Compound/PW C002012 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Decenoyl-CoA
stoichiometric coefficient: 1.0

ReactionCatalysis99870
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: Reaction109633
control type: ACTIVATION

ReactionCatalysis99871
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction109633
control type: ACTIVATION

Reference/ChEBI CHEBI 10723
type: UnificationXref
id: CHEBI:10723
db: ChEBI

Octanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Octanoyl-CoA

Reference/ChEBI CHEBI 28264
type: UnificationXref
id: CHEBI:28264
db: ChEBI

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/ChemSpider 389510
type: UnificationXref
id: 389510
db: ChemSpider

Compound/PW C001719 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hexanoyl-CoA
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

3-Hydroxydecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Hydroxydecanoyl-CoA

ReactionCatalysis99883
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction109643
control type: ACTIVATION

ReactionCatalysis99884
type: Catalysis
controller: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
controlled: Reaction109643
control type: ACTIVATION

Reference/CAS 1264-57-9
type: UnificationXref
id: 1264-57-9
db: CAS

Reference/ChEBI CHEBI 28493
type: UnificationXref
id: CHEBI:28493
db: ChEBI

Reference/CAS 72059-49-5
type: UnificationXref
id: 72059-49-5
db: CAS

3-ketoacyl-CoA thiolase, mitochondrial
type: Complex
component stoichiometry: Protein/13924 Mitochondrial Matrix/Stoichiometry/4.0
cellular location: Mitochondrial Matrix
component: 3-ketoacyl-CoA thiolase, mitochondrial

Reaction109632
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002012 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002002 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002012 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002002 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: (2E)-Decenoyl-CoA
right: Water
spontaneous: false
left: 3-Hydroxydecanoyl-CoA
name: 3-Hydroxydecanoyl-CoA ↔ (2E)-Decenoyl-CoA + Water
conversion direction: REVERSIBLE

Reaction109633
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002004 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002013 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002013 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002004 Mitochondrial Matrix/Stoichiometry/1.0
right: Water
right: (2E)-Octenoyl-CoA
spontaneous: false
left: 3-Hydroxyoctanoyl-CoA
name: 3-Hydroxyoctanoyl-CoA ↔ (2E)-Octenoyl-CoA + Water
conversion direction: REVERSIBLE

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Transport1049
type: Transport
participant stoichiometry: Compound/PW C000497 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000497 Mitochondrion/Stoichiometry/1.0
right: Dodecanoic acid
spontaneous: false
left: Dodecanoic acid
name: Dodecanoic acid (→) Transport: Mus musculus, Cell, Cytosol to Mus musculus, Cell, Mitochondrion
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 16061159
type: UnificationXref
id: 16061159
db: PubChem-compound

Compound/PW C002002 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxydecanoyl-CoA
stoichiometric coefficient: 1.0

Reaction109643
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001144 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002000 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002001 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002001 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002000 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: Hydrogen Ion
right: 3-Oxododecanoyl-CoA
right: NADH
spontaneous: false
left: NAD
left: 3-Hydroxydodecanoyl-CoA
name: 3-Hydroxydodecanoyl-CoA + NAD ↔ 3-Oxododecanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

Reaction109645
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001144 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002003 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002003 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002002 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002002 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: 3-Oxodecanoyl-CoA
right: Hydrogen Ion
right: NADH
spontaneous: false
left: NAD
left: 3-Hydroxydecanoyl-CoA
name: 3-Hydroxydecanoyl-CoA + NAD ↔ 3-Oxodecanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

Reaction109646
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001144 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002004 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002004 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002005 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002005 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: 3-Oxooctanoyl-CoA
right: Hydrogen Ion
right: NADH
spontaneous: false
left: 3-Hydroxyoctanoyl-CoA
left: NAD
name: 3-Hydroxyoctanoyl-CoA + NAD ↔ 3-Oxooctanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

ChemicalStructure/PW C002003
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002004
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002005
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002000
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002001
type: ChemicalStructure
structure format: SMILES

Compound/PW C002003 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxodecanoyl-CoA
stoichiometric coefficient: 1.0

3-Hydroxyoctanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Hydroxyoctanoyl-CoA

Compound/PW C040034 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Decanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05274
xref: Reference/CAS 1264-57-9
xref: Reference/HMDB HMDB0006404
xref: Reference/PubChem-compound 440615
xref: Reference/ChEBI CHEBI 28493
xref: Reference/ChemSpider 389510
chemical formula: C31H54N7O17P3S
molecular weight: 921.251
structure: ChemicalStructure/PW C002742

ChemicalStructure/PW C002002
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis100209
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

ReactionCatalysis100208
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

Protein/13909 Mitochondrial Matrix/Stoichiometry/6.0
type: Stoichiometry
physical entity: Enoyl-CoA hydratase, mitochondrial
stoichiometric coefficient: 6.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Acetyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Acetyl-CoA

Reference/CAS 54684-64-9
type: UnificationXref
id: 54684-64-9
db: CAS

Protein/13903 Mitochondrion/Stoichiometry/4.0
type: Stoichiometry
physical entity: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
stoichiometric coefficient: 4.0

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

Compound/PW C002013 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Octenoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Trifunctional enzyme subunit alpha, mitochondrial
type: Protein
cellular location: Mitochondrial Inner Membrane
entity reference: Trifunctional enzyme subunit alpha, mitochondrial

3-Oxooctanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Oxooctanoyl-CoA

3-Hydroxyoctanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: 3-Hydroxyoctanoyl-CoA

Reference/ChemSpider 26330706
type: UnificationXref
id: 26330706
db: ChemSpider

Compound/Generic69 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: electron-transfer flavoprotein
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reaction109620
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002742 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic69 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic70 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002012 Mitochondrion/Stoichiometry/1.0
right: (2E)-Decenoyl-CoA
right: Reduced electron-transfer flavoprotein
spontaneous: false
left: electron-transfer flavoprotein
left: Decanoyl-CoA
name: Decanoyl-CoA + electron-transfer flavoprotein → (2E)-Decenoyl-CoA + Reduced electron-transfer flavoprotein
conversion direction: LEFT_TO_RIGHT

Reaction109622
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002013 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic69 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic70 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000845 Mitochondrion/Stoichiometry/1.0
right: Reduced electron-transfer flavoprotein
right: (2E)-Octenoyl-CoA
spontaneous: false
left: electron-transfer flavoprotein
left: Octanoyl-CoA
name: Octanoyl-CoA + electron-transfer flavoprotein → (2E)-Octenoyl-CoA + Reduced electron-transfer flavoprotein
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 165436
type: UnificationXref
id: 165436
db: PubChem-compound

NAD
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: NAD

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Enoyl-CoA hydratase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q8BH95
organism: Mus musculus

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
type: ProteinReference
xref: Reference/UniProt P45952
organism: Mus musculus

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/UniProt Q8BH95
type: UnificationXref
id: Q8BH95
db: UniProt

Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids
type: Pathway
pathway order: PathwayEnzymeReaction/1190044
pathway order: PathwaySubPathway/57590
pathway order: PathwayEnzymeReaction/1190043
pathway order: PathwayEnzymeReaction/1190042
pathway order: PathwaySubPathway/57592
pathway order: PathwayEnzymeReaction/1190041
pathway order: PathwaySubPathway/57591
pathway order: PathwayEnzymeReaction/1190048
pathway order: PathwayEnzymeReaction/1190047
pathway order: PathwayEnzymeReaction/1190046
pathway order: PathwayEnzymeReaction/1190045
pathway order: PathwayEnzymeReaction/1190040
pathway order: PathwayEnzymeReaction/1190039
pathway order: PathwayEnzymeReaction/1190038
pathway order: PathwaySubPathway/57593
pathway order: PathwayEnzymeReaction/1190033
pathway order: PathwayEnzymeReaction/1190054
pathway order: PathwayEnzymeReaction/1190053
pathway order: PathwayEnzymeReaction/1190052
pathway order: PathwayEnzymeReaction/1190037
pathway order: PathwayEnzymeReaction/1190036
pathway order: PathwayEnzymeReaction/1190035
pathway order: PathwayEnzymeReaction/1190034
pathway order: PathwayEnzymeReaction/1190051
pathway order: PathwayEnzymeReaction/1190050
pathway order: PathwayTransport/1190055
pathway order: PathwaySubPathway/57589
pathway order: PathwayEnzymeReaction/1190049
pathway component: ReactionCatalysis99869
pathway component: ReactionCatalysis99847
pathway component: Reaction109632
pathway component: ReactionCatalysis99889
pathway component: ReactionCatalysis99868
pathway component: Reaction109633
pathway component: 4.2.1.17
pathway component: ReactionCatalysis99888
pathway component: ReactionCatalysis99850
pathway component: ReactionCatalysis99950
pathway component: ReactionCatalysis99870
pathway component: ReactionCatalysis99892
pathway component: Fatty Acid Elongation in Mitochondria
pathway component: ReactionCatalysis99871
pathway component: ReactionCatalysis99891
pathway component: 2.3.1.16
pathway component: 1.3.8.7
pathway component: Fatty Acid Biosynthesis
pathway component: ReactionCatalysis100435
pathway component: 6.2.1.2
pathway component: ReactionCatalysis100433
pathway component: Citric Acid Cycle
pathway component: Transport1049
pathway component: ReactionCatalysis99957
pathway component: Reaction109620
pathway component: Reaction109643
pathway component: ReactionCatalysis99956
pathway component: Reaction109622
pathway component: Reaction109645
pathway component: ReactionCatalysis99953
pathway component: ReactionCatalysis99954
pathway component: Reaction109646
pathway component: ReactionCatalysis99951
pathway component: ReactionCatalysis99883
pathway component: TransportCatalysis929
pathway component: ReactionCatalysis99884
pathway component: Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
pathway component: Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
pathway component: ReactionCatalysis100209
pathway component: ReactionCatalysis100208
xref: Reference/PathWhiz PW064618
xref: Reference/SMPDB SMP0063640
organism: Mus musculus

Reference/CAS 143-07-7
type: UnificationXref
id: 143-07-7
db: CAS

Protein/13910 Mitochondrial Inner Membrane/Stoichiometry/4.0
type: Stoichiometry
physical entity: Trifunctional enzyme subunit alpha, mitochondrial
stoichiometric coefficient: 4.0

(2E)-Octenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Octenoyl-CoA

Reference/KEGG Compound C03221
type: UnificationXref
id: C03221
db: KEGG Compound

Compound/PW C002742 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Decanoyl-CoA
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Water
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Water

Hydrogen Ion
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Hydrogen Ion

Compound/PW C001928 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lauroyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

(2E)-Dodecenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Dodecenoyl-CoA

Reference/CAS 6245-70-1
type: UnificationXref
id: 6245-70-1
db: CAS

Compound/PW C001099 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Acyl-coenzyme A synthetase ACSM1, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q91VA0
organism: Mus musculus

Compound/PW C001959 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Dodecenoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C002001 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxododecanoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C002000 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxydodecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003571
type: UnificationXref
id: HMDB0003571
db: HMDB

Compound/PW C002004 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxyoctanoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C002005 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxooctanoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 1264-52-4
type: UnificationXref
id: 1264-52-4
db: CAS

(2E)-Octenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: (2E)-Octenoyl-CoA

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Compound/PW C000940 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

3-Oxododecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Oxododecanoyl-CoA

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C002012
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002013
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

ReactionCatalysis100435
type: Catalysis
controller: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
controlled: 1.3.8.7
control type: ACTIVATION

ReactionCatalysis100433
type: Catalysis
controller: Acyl-coenzyme A synthetase ACSM1, mitochondrial
controlled: 6.2.1.2
control type: ACTIVATION

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/ChemSpider 3756
type: UnificationXref
id: 3756
db: ChemSpider

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

(2E)-Decenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Decenoyl-CoA

Acyl-coenzyme A synthetase ACSM1, mitochondrial
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Acyl-coenzyme A synthetase ACSM1, mitochondrial

(2E)-Decenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: (2E)-Decenoyl-CoA

Acetyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Acetyl-CoA
name: SubPathwayInput

Compound/PW C002004 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxyoctanoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 78303-19-2
type: UnificationXref
id: 78303-19-2
db: CAS

Adenosine triphosphate
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Adenosine triphosphate

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002000 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001959 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001959 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002000 Mitochondrial Matrix/Stoichiometry/1.0
right: (2E)-Dodecenoyl-CoA
right: Water
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxydodecanoyl-CoA
name: 3-Hydroxydodecanoyl-CoA ↔ (2E)-Dodecenoyl-CoA + Water
conversion direction: REVERSIBLE

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/ChemSpider 371
type: UnificationXref
id: 371
db: ChemSpider

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
type: Complex
component stoichiometry: Protein/13903 Mitochondrion/Stoichiometry/4.0
cellular location: Mitochondrion
component: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/HMDB HMDB0002845
type: UnificationXref
id: HMDB0002845
db: HMDB

Compound/PW C002003 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxodecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 5060-32-2
type: UnificationXref
id: 5060-32-2
db: CAS

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

NADH
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: NADH

Compound/PW C002013 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Octenoyl-CoA
stoichiometric coefficient: 1.0

Reference/TAXONOMY 10090
type: UnificationXref
id: 10090
db: TAXONOMY

Reference/PubChem-compound 440608
type: UnificationXref
id: 440608
db: PubChem-compound

Reference/HMDB HMDB0003938
type: UnificationXref
id: HMDB0003938
db: HMDB

Reference/PubChem-compound 440606
type: UnificationXref
id: 440606
db: PubChem-compound

Dodecanoic acid
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Dodecanoic acid

Reference/HMDB HMDB0003939
type: UnificationXref
id: HMDB0003939
db: HMDB

Reference/HMDB HMDB0003936
type: UnificationXref
id: HMDB0003936
db: HMDB

Reference/PubChem-compound 440604
type: UnificationXref
id: 440604
db: PubChem-compound

Reference/PubChem-compound 380
type: UnificationXref
id: 380
db: PubChem-compound

Reference/PubChem-compound 440603
type: UnificationXref
id: 440603
db: PubChem-compound

Reference/HMDB HMDB0003937
type: UnificationXref
id: HMDB0003937
db: HMDB

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/HMDB HMDB0003941
type: UnificationXref
id: HMDB0003941
db: HMDB

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

3-Oxooctanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: 3-Oxooctanoyl-CoA

Fatty Acid Elongation in Mitochondria
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway57590
pathway component: SubPathwayInteraction57590
xref: Reference/PathWhiz PW000022
xref: Reference/SMPDB SMP0000054
name: SubPathway

Reference/HMDB HMDB0003940
type: UnificationXref
id: HMDB0003940
db: HMDB

Dodecanoic acid
type: SmallMoleculeReference
xref: Reference/ChemSpider 3756
xref: Reference/KEGG Compound C02679
xref: Reference/CAS 143-07-7
xref: Reference/ChEBI CHEBI 30805
xref: Reference/HMDB HMDB0000638
xref: Reference/PubChem-compound 3893
chemical formula: C12H24O2
molecular weight: 200.17763
structure: ChemicalStructure/PW C000497

Reduced electron-transfer flavoprotein
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Reduced electron-transfer flavoprotein

Reference/SMPDB SMP0063640
type: UnificationXref
id: SMP0063640
db: SMPDB

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Citric Acid Cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway57592
pathway component: SubPathwayInteraction57592
xref: Reference/PathWhiz PW000005
xref: Reference/SMPDB SMP0000057
name: SubPathway

Compound/PW C001144 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003949
type: UnificationXref
id: HMDB0003949
db: HMDB

Reference/HMDB HMDB0003948
type: UnificationXref
id: HMDB0003948
db: HMDB

Compound/PW C002005 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxooctanoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C002002 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxydecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/UniProt Q8BWT1
type: UnificationXref
id: Q8BWT1
db: UniProt

Reference/PubChem-compound 45266564
type: UnificationXref
id: 45266564
db: PubChem-compound

NAD
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: NAD

ChemicalStructure/PW C002742
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Coenzyme A

Reference/HMDB HMDB0003712
type: UnificationXref
id: HMDB0003712
db: HMDB

3-Oxododecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: 3-Oxododecanoyl-CoA

Protein/13924 Mitochondrial Matrix/Stoichiometry/4.0
type: Stoichiometry
physical entity: 3-ketoacyl-CoA thiolase, mitochondrial
stoichiometric coefficient: 4.0

Mitochondrion
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005739

Enoyl-CoA hydratase, mitochondrial
type: Complex
component stoichiometry: Protein/13909 Mitochondrial Matrix/Stoichiometry/6.0
cellular location: Mitochondrial Matrix
component: Enoyl-CoA hydratase, mitochondrial

Reference/ChEBI CHEBI 15521
type: UnificationXref
id: CHEBI:15521
db: ChEBI

electron-transfer flavoprotein
type: SmallMolecule
cellular location: Mitochondrion
entity reference: electron-transfer flavoprotein

Compound/PW C002012 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Decenoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

(2E)-Decenoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05275
xref: Reference/BioCyc T2-DECENOYL-COA
xref: Reference/ChemSpider 4444334
xref: Reference/ChEBI CHEBI 10723
xref: Reference/CAS 10018-95-8
xref: Reference/HMDB HMDB0003948
xref: Reference/PubChem-compound 5280768
chemical formula: C31H52N7O17P3S
molecular weight: 919.23535
structure: ChemicalStructure/PW C002012

(2E)-Octenoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChemSpider 4444335
xref: Reference/KEGG Compound C05276
xref: Reference/ChEBI CHEBI 27537
xref: Reference/HMDB HMDB0003949
xref: Reference/PubChem-compound 5280769
xref: Reference/CAS 10018-94-7
chemical formula: C29H48N7O17P3S
molecular weight: 891.20404
structure: ChemicalStructure/PW C002013

ChemicalStructure/PW C000497
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCC(O)=O

Compound/PW C000721 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

SubPathwayInteraction57592
type: Interaction
name: SubPathwayReaction
name: SubPathway57592Reaction
participant: Acetyl-CoA

SubPathwayInteraction57593
type: Interaction
name: SubPathway57593Reaction
name: SubPathwayReaction
participant: Hexanoyl-CoA

Reference/ChEBI CHEBI 15533
type: UnificationXref
id: CHEBI:15533
db: ChEBI

SubPathwayInteraction57590
type: Interaction
name: SubPathway57590Reaction
name: SubPathwayReaction
participant: Dodecanoic acid

SubPathwayInteraction57591
type: Interaction
name: SubPathwayReaction
name: SubPathway57591Reaction
participant: Lauroyl-CoA

Reference/ChEBI CHEBI 57330
type: UnificationXref
id: CHEBI:57330
db: ChEBI

Reference/PubChem-compound 440615
type: UnificationXref
id: 440615
db: PubChem-compound

Trifunctional enzyme, mitochondrial
type: Complex
component stoichiometry: Protein/13910 Mitochondrial Inner Membrane/Stoichiometry/4.0
cellular location: Mitochondrial Inner Membrane
component: Trifunctional enzyme subunit alpha, mitochondrial

Enoyl-CoA hydratase, mitochondrial
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Enoyl-CoA hydratase, mitochondrial

Reference/KEGG Compound C05264
type: UnificationXref
id: C05264
db: KEGG Compound

Reference/KEGG Compound C05263
type: UnificationXref
id: C05263
db: KEGG Compound

Reference/KEGG Compound C05266
type: UnificationXref
id: C05266
db: KEGG Compound

Reference/KEGG Compound C05265
type: UnificationXref
id: C05265
db: KEGG Compound

Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway57591
pathway component: SubPathwayInteraction57591
xref: Reference/PathWhiz PW000173
xref: Reference/SMPDB SMP0000482
name: SubPathway

Reference/GENE ONTOLOGY GO 0005759
type: UnificationXref
id: GO:0005759
db: GENE ONTOLOGY

Octanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Octanoyl-CoA

Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway57593
pathway component: SubPathwayInteraction57593
xref: Reference/SMPDB SMP0000480
xref: Reference/PathWhiz PW000171
name: SubPathway

Reference/KEGG Compound C05262
type: UnificationXref
id: C05262
db: KEGG Compound

Reference/ChEBI CHEBI 27868
type: UnificationXref
id: CHEBI:27868
db: ChEBI

Reference/SMPDB SMP0000057
type: UnificationXref
id: SMP0000057
db: SMPDB

Reference/SMPDB SMP0000054
type: UnificationXref
id: SMP0000054
db: SMPDB

Compound/PW C001420 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Dodecanoic acid
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Dodecanoic acid

Reference/KEGG Compound C05267
type: UnificationXref
id: C05267
db: KEGG Compound

Reference/PubChem-compound 3893
type: UnificationXref
id: 3893
db: PubChem-compound

Hydrogen Ion
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Hydrogen Ion

Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/KEGG Compound C05275
type: UnificationXref
id: C05275
db: KEGG Compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Reference/KEGG Compound C05274
type: UnificationXref
id: C05274
db: KEGG Compound

Reference/KEGG Compound C05276
type: UnificationXref
id: C05276
db: KEGG Compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/KEGG Compound C05270
type: UnificationXref
id: C05270
db: KEGG Compound

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

SubPathwayInteraction57589
type: Interaction
name: SubPathway57589Reaction
name: SubPathwayReaction
participant: Dodecanoic acid

Decanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Decanoyl-CoA

(2E)-Dodecenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: (2E)-Dodecenoyl-CoA

Water
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Water

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

3-Hydroxydodecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 72059-49-5
xref: Reference/ChemSpider 389501
xref: Reference/ChEBI CHEBI 27668
xref: Reference/KEGG Compound C05262
xref: Reference/HMDB HMDB0003936
xref: Reference/PubChem-compound 440603
chemical formula: C33H58N7O18P3S
molecular weight: 965.27716
structure: ChemicalStructure/PW C002000

3-Oxododecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05263
xref: Reference/ChemSpider 389502
xref: Reference/CAS 78303-19-2
xref: Reference/ChEBI CHEBI 27868
xref: Reference/PubChem-compound 440604
xref: Reference/HMDB HMDB0003937
chemical formula: C33H56N7O18P3S
molecular weight: 963.26154
structure: ChemicalStructure/PW C002001

Reference/GENE ONTOLOGY GO 0005739
type: UnificationXref
id: GO:0005739
db: GENE ONTOLOGY

3-Hydroxydecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05264
xref: Reference/ChEBI CHEBI 28325
xref: Reference/CAS 6245-70-1
xref: Reference/ChemSpider 17220838
xref: Reference/HMDB HMDB0003938
xref: Reference/PubChem-compound 16061159
chemical formula: C31H54N7O18P3S
molecular weight: 937.2459
structure: ChemicalStructure/PW C002002

Compound/PW C000940 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

3-Oxodecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05265
xref: Reference/ChEBI CHEBI 28528
xref: Reference/ChemSpider 389504
xref: Reference/PubChem-compound 440606
xref: Reference/HMDB HMDB0003939
xref: Reference/CAS 50411-91-1
chemical formula: C31H52N7O18P3S
molecular weight: 935.2302
structure: ChemicalStructure/PW C002003

3-Hydroxyoctanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 28632
xref: Reference/KEGG Compound C05266
xref: Reference/HMDB HMDB0003940
xref: Reference/CAS 79171-48-5
xref: Reference/PubChem-compound 53477508
chemical formula: C29H50N7O18P3S
molecular weight: 909.2146
structure: ChemicalStructure/PW C002004

Decanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Decanoyl-CoA

3-Oxooctanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003941
xref: Reference/ChemSpider 389506
xref: Reference/PubChem-compound 440608
xref: Reference/BioCyc 7-METHYL-3-OXOOCTANOYL-COA
xref: Reference/ChEBI CHEBI 28264
xref: Reference/KEGG Compound C05267
xref: Reference/CAS 54684-64-9
chemical formula: C29H48N7O18P3S
molecular weight: 907.1989
structure: ChemicalStructure/PW C002005

Compound/PW C000497 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dodecanoic acid
stoichiometric coefficient: 1.0

3-Hydroxydecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: 3-Hydroxydecanoyl-CoA

Solute carrier family 25 member 44
type: ProteinReference
xref: Reference/UniProt Q8BGF9

Compound/PW C000170 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/CAS 10018-95-8
type: UnificationXref
id: 10018-95-8
db: CAS

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis99889
type: Catalysis
controller: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
controlled: Reaction109645
control type: ACTIVATION

electron-transfer flavoprotein
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 5086

3-Oxodecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Oxodecanoyl-CoA

Compound/PW C000414 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

ReactionCatalysis99888
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction109645
control type: ACTIVATION

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C000845
type: ChemicalStructure
structure format: SMILES

Reduced electron-transfer flavoprotein
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 5086

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Reference/SMPDB SMP0000480
type: UnificationXref
id: SMP0000480
db: SMPDB

ReactionCatalysis99892
type: Catalysis
controller: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
controlled: Reaction109646
control type: ACTIVATION

ReactionCatalysis99891
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction109646
control type: ACTIVATION

Reference/ChEBI CHEBI 28528
type: UnificationXref
id: CHEBI:28528
db: ChEBI

Mitochondrial Matrix
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005759

Reference/PubChem-compound 5280769
type: UnificationXref
id: 5280769
db: PubChem-compound

Reference/CAS 50411-91-1
type: UnificationXref
id: 50411-91-1
db: CAS

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/PubChem-compound 5280768
type: UnificationXref
id: 5280768
db: PubChem-compound

Reference/SMPDB SMP0000482
type: UnificationXref
id: SMP0000482
db: SMPDB

Reference/ChemSpider 395736
type: UnificationXref
id: 395736
db: ChemSpider

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

3-Hydroxydodecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: 3-Hydroxydodecanoyl-CoA

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Reference/ChEBI CHEBI 28632
type: UnificationXref
id: CHEBI:28632
db: ChEBI

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/ChEBI CHEBI 27668
type: UnificationXref
id: CHEBI:27668
db: ChEBI

Compound/PW C002742 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Decanoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 79171-48-5
type: UnificationXref
id: 79171-48-5
db: CAS

Reference/ChEBI CHEBI 27540
type: UnificationXref
id: CHEBI:27540
db: ChEBI

Reference/KEGG Compound C01944
type: UnificationXref
id: C01944
db: KEGG Compound

Compound/PW C001959 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Dodecenoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C000845 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Octanoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Compound/PW C000497 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dodecanoic acid
stoichiometric coefficient: 1.0

(2E)-Dodecenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: (2E)-Dodecenoyl-CoA

Compound/PW C000845 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Octanoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C000032 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

3-Hydroxydodecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Hydroxydodecanoyl-CoA

Reference/ChEBI CHEBI 27537
type: UnificationXref
id: CHEBI:27537
db: ChEBI

Reference/UniProt Q91VA0
type: UnificationXref
id: Q91VA0
db: UniProt

Fatty Acid Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway57589
pathway component: SubPathwayInteraction57589
xref: Reference/PathWhiz PW000167
xref: Reference/SMPDB SMP0000456
name: SubPathway

ChemicalStructure/PW C001928
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C01832
type: UnificationXref
id: C01832
db: KEGG Compound

Octanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Octanoyl-CoA

Reference/PubChem-compound 449118
type: UnificationXref
id: 449118
db: PubChem-compound

Reference/UniProt Q61425
type: UnificationXref
id: Q61425
db: UniProt

Reference/ChEBI CHEBI 30805
type: UnificationXref
id: CHEBI:30805
db: ChEBI

Compound/PW C000845 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Octanoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C001959 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Dodecenoyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc T2-DECENOYL-COA
type: UnificationXref
id: T2-DECENOYL-COA
db: BioCyc

Reference/PathWhiz PW000022
type: UnificationXref
id: PW000022
db: PathWhiz

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Reference/ChemSpider 145018
type: UnificationXref
id: 145018
db: ChemSpider

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/ChEBI CHEBI 28325
type: UnificationXref
id: CHEBI:28325
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/SMPDB SMP0000456
type: UnificationXref
id: SMP0000456
db: SMPDB

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-7222
type: UnificationXref
id: CPD-7222
db: BioCyc

Reference/UniProt Q8BMS1
type: UnificationXref
id: Q8BMS1
db: UniProt

Compound/PW C002000 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxydodecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/UniProt Q8BGF9
type: UnificationXref
id: Q8BGF9
db: UniProt

Compound/PW C002742 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Decanoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 4444334
type: UnificationXref
id: 4444334
db: ChemSpider

Reference/ChemSpider 4444335
type: UnificationXref
id: 4444335
db: ChemSpider

ChemicalStructure/PW C001719
type: ChemicalStructure
structure format: SMILES

Compound/PW C002001 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxododecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000005
type: UnificationXref
id: PW000005
db: PathWhiz

Reference/CAS 6244-92-4
type: UnificationXref
id: 6244-92-4
db: CAS

ChemicalStructure/PW C001959
type: ChemicalStructure
structure format: SMILES

Reference/CAS 10018-94-7
type: UnificationXref
id: 10018-94-7
db: CAS

1.3.8.7
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001959 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic69 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic70 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001928 Mitochondrion/Stoichiometry/1.0
right: (2E)-Dodecenoyl-CoA
right: Reduced electron-transfer flavoprotein
spontaneous: false
EC number: 1.3.8.7
left: Lauroyl-CoA
left: electron-transfer flavoprotein
name: Lauroyl-CoA + electron-transfer flavoprotein → (2E)-Dodecenoyl-CoA + Reduced electron-transfer flavoprotein
conversion direction: LEFT_TO_RIGHT

6.2.1.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000032 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001928 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000497 Mitochondrial Matrix/Stoichiometry/1.0
right: Lauroyl-CoA
right: Adenosine monophosphate
right: Pyrophosphate
spontaneous: false
EC number: 6.2.1.2
left: Coenzyme A
left: Adenosine triphosphate
left: Dodecanoic acid
name: Adenosine triphosphate + Coenzyme A + Dodecanoic acid → Adenosine monophosphate + Lauroyl-CoA + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 1066-12-2
type: UnificationXref
id: 1066-12-2
db: CAS

Compound/PW C001719 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hexanoyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000638
type: UnificationXref
id: HMDB0000638
db: HMDB

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Compound/PW C000497 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dodecanoic acid
stoichiometric coefficient: 1.0