ReactionCatalysis39985
type: Catalysis
controller: Choline-phosphate cytidylyltransferase 1
controlled: 2.7.7.57
control type: ACTIVATION

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

ReactionCatalysis39989
type: Catalysis
controller: Phospholipase D alpha
controlled: Reaction111680
control type: ACTIVATION

ReactionCatalysis39986
type: Catalysis
controller: Choline-phosphate cytidylyltransferase 1
controlled: 2.7.7.-
control type: ACTIVATION

Reference/KEGG Compound C02737
type: UnificationXref
id: C02737
db: KEGG Compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 440026
type: UnificationXref
id: 440026
db: PubChem-compound

Reaction111676
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059416/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C060211/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: PE-NMe2(20:0/20:1(11Z))
spontaneous: false
left: PE-NMe(20:0/20:1(11Z))
left: S-Adenosylmethionine
name: PE-NMe(20:0/20:1(11Z)) + S-Adenosylmethionine → PE-NMe2(20:0/20:1(11Z)) + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 25201906
type: UnificationXref
id: 25201906
db: PubChem-compound

Reaction111675
type: BiochemicalReaction
participant stoichiometry: Compound/PW C060934/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C005278/Stoichiometry/1.0
right: PE(20:0/20:1(11Z))
right: Carbon dioxide
spontaneous: false
left: PS(20:0/20:1(11Z))
name: PS(20:0/20:1(11Z)) → Carbon dioxide + PE(20:0/20:1(11Z))
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis39979
type: Catalysis
controller: Ethanolamine-phosphate cytidylyltransferase
controlled: 2.7.7.14
control type: ACTIVATION

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Reference/HMDB HMDB0000097
type: UnificationXref
id: HMDB0000097
db: HMDB

Reference/HMDB HMDB0001185
type: UnificationXref
id: HMDB0001185
db: HMDB

Reaction111679
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000149/Stoichiometry/1.0
participant stoichiometry: Compound/PW C005278/Stoichiometry/1.0
right: DG(20:0/20:1(11Z)/0:0)
right: O-Phosphoethanolamine
spontaneous: false
left: Water
left: PE(20:0/20:1(11Z))
name: PE(20:0/20:1(11Z)) + Water → DG(20:0/20:1(11Z)/0:0) + O-Phosphoethanolamine
conversion direction: LEFT_TO_RIGHT

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reaction111678
type: BiochemicalReaction
participant stoichiometry: Compound/PW C003420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001201/Stoichiometry/1.0
participant stoichiometry: Compound/PW C005278/Stoichiometry/1.0
right: Cytidine monophosphate
right: PE(20:0/20:1(11Z))
spontaneous: false
left: DG(20:0/20:1(11Z)/0:0)
left: CDP-ethanolamine
name: CDP-ethanolamine + DG(20:0/20:1(11Z)/0:0) → Cytidine monophosphate + PE(20:0/20:1(11Z))
conversion direction: LEFT_TO_RIGHT

Reaction111677
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004323/Stoichiometry/1.0
participant stoichiometry: Compound/PW C060211/Stoichiometry/1.0
right: PC(20:0/20:1(11Z))
right: S-Adenosylhomocysteine
spontaneous: false
left: PE-NMe2(20:0/20:1(11Z))
left: S-Adenosylmethionine
name: PE-NMe2(20:0/20:1(11Z)) + S-Adenosylmethionine → PC(20:0/20:1(11Z)) + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0115076
type: UnificationXref
id: HMDB0115076
db: HMDB

ReactionCatalysis39974
type: Catalysis
controller: Choline/ethanolamine kinase
controlled: Reaction49849
control type: ACTIVATION

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Reference/ChemSpider 13207
type: UnificationXref
id: 13207
db: ChemSpider

Reference/ChEBI CHEBI 17115
type: UnificationXref
id: CHEBI:17115
db: ChEBI

Compound/PW C000064/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C059092
type: ChemicalStructure
structure format: SMILES

Compound/PW C005278 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

PS(20:0/20:1(11Z))
type: SmallMolecule
entity reference: PS(20:0/20:1(11Z))

PE-NMe(20:0/20:1(11Z))
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: PE-NMe(20:0/20:1(11Z))

Compound/PW C059090/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-N-methylethanolamine
stoichiometric coefficient: 1.0

2.7.8.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C003420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004323/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Cytidine monophosphate
right: PC(20:0/20:1(11Z))
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.8.2
left: DG(20:0/20:1(11Z)/0:0)
left: CDP-Choline
name: CDP-Choline + DG(20:0/20:1(11Z)/0:0) → Cytidine monophosphate + Hydrogen Ion + PC(20:0/20:1(11Z))
conversion direction: LEFT_TO_RIGHT

2.7.8.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059092/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C060211/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Cytidine monophosphate
right: PE-NMe2(20:0/20:1(11Z))
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.8.-
left: DG(20:0/20:1(11Z)/0:0)
left: CDP-N-dimethylethanolamine
name: CDP-N-dimethylethanolamine + DG(20:0/20:1(11Z)/0:0) → Cytidine monophosphate + Hydrogen Ion + PE-NMe2(20:0/20:1(11Z))
conversion direction: LEFT_TO_RIGHT

Compound/PW C004323/Stoichiometry/1.0
type: Stoichiometry
physical entity: PC(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

2.7.8.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059416/Stoichiometry/1.0
participant stoichiometry: Compound/PW C059090/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Cytidine monophosphate
right: PE-NMe(20:0/20:1(11Z))
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.8.-
left: DG(20:0/20:1(11Z)/0:0)
left: CDP-N-methylethanolamine
name: CDP-N-methylethanolamine + DG(20:0/20:1(11Z)/0:0) → Cytidine monophosphate + Hydrogen Ion + PE-NMe(20:0/20:1(11Z))
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reaction111680
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062494/Stoichiometry/1.0
participant stoichiometry: Compound/PW C005278/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000096/Stoichiometry/1.0
right: Ethanolamine
right: PA(20:0/20:1(11Z))
spontaneous: false
left: Water
left: PE(20:0/20:1(11Z))
name: PE(20:0/20:1(11Z)) + Water → Ethanolamine + PA(20:0/20:1(11Z))
conversion direction: LEFT_TO_RIGHT

Reaction111685
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062494/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004323/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000065/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: PA(20:0/20:1(11Z))
right: Hydrogen Ion
right: Choline
spontaneous: false
left: PC(20:0/20:1(11Z))
left: Water
name: PC(20:0/20:1(11Z)) + Water → Choline + Hydrogen Ion + PA(20:0/20:1(11Z))
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C059090
type: ChemicalStructure
structure format: SMILES

Reaction111684
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001202/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004323/Stoichiometry/1.0
right: DG(20:0/20:1(11Z)/0:0)
right: Phosphorylcholine
spontaneous: false
left: PC(20:0/20:1(11Z))
left: Water
name: PC(20:0/20:1(11Z)) + Water → DG(20:0/20:1(11Z)/0:0) + Phosphorylcholine
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 110296
type: UnificationXref
id: 110296
db: ChemSpider

Compound/PW C000065/Stoichiometry/1.0
type: Stoichiometry
physical entity: Choline
stoichiometric coefficient: 1.0

ChemicalStructure/PW C062494
type: ChemicalStructure
structure format: SMILES

Transport1476
type: Transport
participant stoichiometry: Compound/PW C004323 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004323 Cytoplasm/Stoichiometry/1.0
right: PC(20:0/20:1(11Z))
spontaneous: false
left: PC(20:0/20:1(11Z))
name: PC(20:0/20:1(11Z)) (→) Transport: Arabidopsis thaliana, Cell, Endoplasmic Reticulum to Arabidopsis thaliana, Cell, Cytoplasm
conversion direction: LEFT_TO_RIGHT

Transport1475
type: Transport
participant stoichiometry: Compound/PW C060211 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C060211 Cytoplasm/Stoichiometry/1.0
right: PE-NMe2(20:0/20:1(11Z))
spontaneous: false
left: PE-NMe2(20:0/20:1(11Z))
name: PE-NMe2(20:0/20:1(11Z)) (→) Transport: Arabidopsis thaliana, Cell, Cytoplasm to Arabidopsis thaliana, Cell, Endoplasmic Reticulum
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 24766936
type: UnificationXref
id: 24766936
db: ChemSpider

S-Adenosylmethionine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 24762165
xref: Reference/KEGG Compound C00019
xref: Reference/ChemSpider 31983
xref: Reference/ChEBI CHEBI 15414
xref: Reference/CAS 485-80-3
xref: Reference/BioCyc S-ADENOSYLMETHIONINE
xref: Reference/HMDB HMDB0001185
chemical formula: C15H23N6O5S
molecular weight: 399.14505
structure: ChemicalStructure/PW C000921

Transport1474
type: Transport
participant stoichiometry: Compound/PW C059416 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C059416 Endoplasmic Reticulum/Stoichiometry/1.0
right: PE-NMe(20:0/20:1(11Z))
spontaneous: false
left: PE-NMe(20:0/20:1(11Z))
name: PE-NMe(20:0/20:1(11Z)) (→) Transport: Arabidopsis thaliana, Cell, Cytoplasm to Arabidopsis thaliana, Cell, Endoplasmic Reticulum
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 700
type: UnificationXref
id: 700
db: PubChem-compound

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Transport1473
type: Transport
participant stoichiometry: Compound/PW C005278 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C005278 Cytoplasm/Stoichiometry/1.0
right: PE(20:0/20:1(11Z))
spontaneous: false
left: PE(20:0/20:1(11Z))
name: PE(20:0/20:1(11Z)) (→) Transport: Arabidopsis thaliana, Cell, Endoplasmic Reticulum to Arabidopsis thaliana, Cell, Cytoplasm
conversion direction: LEFT_TO_RIGHT

Compound/PW C000149/Stoichiometry/1.0
type: Stoichiometry
physical entity: O-Phosphoethanolamine
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Compound/PW C043034/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-Choline
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6323481
type: UnificationXref
id: 6323481
db: PubChem-compound

Reference/KEGG Compound C00570
type: UnificationXref
id: C00570
db: KEGG Compound

Reference/UniProt Q9SAH5
type: UnificationXref
id: Q9SAH5
db: UniProt

ReactionCatalysis39995
type: Catalysis
controller: Choline/ethanolaminephosphotransferase 1
controlled: 2.7.8.-
control type: ACTIVATION

Reference/ChemSpider 5736
type: UnificationXref
id: 5736
db: ChemSpider

ReactionCatalysis39996
type: Catalysis
controller: Choline/ethanolaminephosphotransferase 1
controlled: 2.7.8.-
control type: ACTIVATION

ReactionCatalysis39993
type: Catalysis
controller: Choline/ethanolaminephosphotransferase 1
controlled: 2.7.8.2
control type: ACTIVATION

Reference/ChEBI CHEBI 18303
type: UnificationXref
id: CHEBI:18303
db: ChEBI

ReactionCatalysis39994
type: Catalysis
controller: Choline/ethanolaminephosphotransferase 1
controlled: Reaction111678
control type: ACTIVATION

ReactionCatalysis39999
type: Catalysis
controller: Phosphatidyl-N-methylethanolamine N-methyltransferase
controlled: Reaction111677
control type: ACTIVATION

ReactionCatalysis39997
type: Catalysis
controller: Phosphatidylserine decarboxylase proenzyme 3
controlled: Reaction111675
control type: ACTIVATION

ReactionCatalysis39998
type: Catalysis
controller: Phosphatidyl-N-methylethanolamine N-methyltransferase
controlled: Reaction111676
control type: ACTIVATION

Reference/ChEBI CHEBI 16000
type: UnificationXref
id: CHEBI:16000
db: ChEBI

Reference/KEGG Compound C00346
type: UnificationXref
id: C00346
db: KEGG Compound

Reference/KEGG Compound C00588
type: UnificationXref
id: C00588
db: KEGG Compound

ReactionCatalysis39991
type: Catalysis
controller: Phospholipase D alpha
controlled: Reaction111685
control type: ACTIVATION

ReactionCatalysis39992
type: Catalysis
controller: Non-specific phospholipase C4
controlled: Reaction111684
control type: ACTIVATION

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ReactionCatalysis39990
type: Catalysis
controller: Non-specific phospholipase C4
controlled: Reaction111679
control type: ACTIVATION

PE(20:0/20:1(11Z))
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0009230
xref: Reference/PubChem-compound 9546851
xref: Reference/BioCyc L-1-PHOSPHATIDYL-ETHANOLAMINE
xref: Reference/ChemSpider 7825801
xref: Reference/KEGG Compound C00350
chemical formula: C45H88NO8P
molecular weight: 801.62476
structure: ChemicalStructure/PW C005278

Compound/PW C060211 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE-NMe2(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Reference/BioCyc CPD4FS-1
type: UnificationXref
id: CPD4FS-1
db: BioCyc

PE(20:0/20:1(11Z))
type: SmallMolecule
entity reference: PE(20:0/20:1(11Z))

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/ChemSpider 7825801
type: UnificationXref
id: 7825801
db: ChemSpider

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

ChemicalStructure/PW C000921
type: ChemicalStructure
structure format: SMILES

Reference/CAS 979-92-0
type: UnificationXref
id: 979-92-0
db: CAS

Reference/KEGG Compound C00350
type: UnificationXref
id: C00350
db: KEGG Compound

PE(20:0/20:1(11Z))
type: SmallMolecule
cellular location: Cytoplasm
entity reference: PE(20:0/20:1(11Z))

Reference/KEGG Compound C00114
type: UnificationXref
id: C00114
db: KEGG Compound

Reference/BioCyc PHOSPHATIDYLCHOLINE
type: UnificationXref
id: PHOSPHATIDYLCHOLINE
db: BioCyc

Reference/UniProt Q9MA74
type: UnificationXref
id: Q9MA74
db: UniProt

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/CAS 1071-23-4
type: UnificationXref
id: 1071-23-4
db: CAS

S-Adenosylhomocysteine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 25246222
xref: Reference/ChemSpider 388301
xref: Reference/BioCyc ADENOSYL-HOMO-CYS
xref: Reference/CAS 979-92-0
xref: Reference/KEGG Compound C00021
xref: Reference/ChEBI CHEBI 16680
xref: Reference/HMDB HMDB0000939
chemical formula: C14H20N6O5S
molecular weight: 384.12158
structure: ChemicalStructure/PW C000749

Reference/UniProt Q9M9H6
type: UnificationXref
id: Q9M9H6
db: UniProt

ReactionCatalysis37636
type: Catalysis
controller: Choline-phosphate cytidylyltransferase 1
controlled: 2.7.7.15
control type: ACTIVATION

Reference/ChemSpider 7822743
type: UnificationXref
id: 7822743
db: ChemSpider

Compound/PW C004323 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: PC(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0114194
type: UnificationXref
id: HMDB0114194
db: HMDB

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/BioCyc CDP-CHOLINE
type: UnificationXref
id: CDP-CHOLINE
db: BioCyc

ReactionCatalysis37631
type: Catalysis
controller: Choline/ethanolamine kinase
controlled: 2.7.1.82
control type: ACTIVATION

ReactionCatalysis37630
type: Catalysis
controller: Serine decarboxylase
controlled: 4.1.1.-
control type: ACTIVATION

ReactionCatalysis37633
type: Catalysis
controller: Phosphoethanolamine N-methyltransferase 1
controlled: 2.1.1.103
control type: ACTIVATION

ReactionCatalysis37632
type: Catalysis
controller: Phosphoethanolamine N-methyltransferase 1
controlled: 2.1.1.103
control type: ACTIVATION

ReactionCatalysis37635
type: Catalysis
controller: Phosphoethanolamine/phosphocholine phosphatase
controlled: 3.1.3.75
control type: ACTIVATION

ReactionCatalysis37634
type: Catalysis
controller: Phosphoethanolamine N-methyltransferase 1
controlled: Reaction47487
control type: ACTIVATION

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C01210
type: UnificationXref
id: C01210
db: KEGG Compound

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

ChemicalStructure/PW C005278
type: ChemicalStructure
structure format: SMILES

PE(20:0/20:1(11Z))
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: PE(20:0/20:1(11Z))

Reference/KEGG Compound C00019
type: UnificationXref
id: C00019
db: KEGG Compound

Compound/PW C057893/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Dimethylethanolamine phosphate
stoichiometric coefficient: 1.0

4.1.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000120/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000096/Stoichiometry/1.0
right: Ethanolamine
right: Carbon dioxide
spontaneous: false
EC number: 4.1.1.-
left: Hydrogen Ion
left: L-Serine
name: Hydrogen Ion + L-Serine → Carbon dioxide + Ethanolamine
conversion direction: LEFT_TO_RIGHT

2.7.1.82
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000149/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000096/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: O-Phosphoethanolamine
spontaneous: false
EC number: 2.7.1.82
left: Ethanolamine
left: Adenosine triphosphate
name: Adenosine triphosphate + Ethanolamine → Adenosine diphosphate + Hydrogen Ion + O-Phosphoethanolamine
conversion direction: LEFT_TO_RIGHT

2.1.1.103
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000149/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057892/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: N-Methylethanolamine phosphate
spontaneous: false
EC number: 2.1.1.103
left: O-Phosphoethanolamine
left: S-Adenosylmethionine
name: O-Phosphoethanolamine + S-Adenosylmethionine → Hydrogen Ion + N-Methylethanolamine phosphate + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

2.1.1.103
type: BiochemicalReaction
participant stoichiometry: Compound/PW C057893/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057892/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: N-Dimethylethanolamine phosphate
spontaneous: false
EC number: 2.1.1.103
left: N-Methylethanolamine phosphate
left: S-Adenosylmethionine
name: N-Methylethanolamine phosphate + S-Adenosylmethionine → Hydrogen Ion + N-Dimethylethanolamine phosphate + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reaction47487
type: BiochemicalReaction
participant stoichiometry: Compound/PW C057893/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001202/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: Phosphorylcholine
spontaneous: false
left: N-Dimethylethanolamine phosphate
left: S-Adenosylmethionine
name: N-Dimethylethanolamine phosphate + S-Adenosylmethionine → Hydrogen Ion + Phosphorylcholine + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

3.1.3.75
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001202/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000065/Stoichiometry/1.0
right: Choline
right: Pyrophosphate
spontaneous: false
EC number: 3.1.3.75
left: Water
left: Phosphorylcholine
name: Phosphorylcholine + Water → Choline + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

2.7.7.15
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001202/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043034/Stoichiometry/1.0
right: CDP-Choline
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.15
left: Cytidine triphosphate
left: Phosphorylcholine
name: Cytidine triphosphate + Phosphorylcholine → CDP-Choline + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 52332
type: UnificationXref
id: CHEBI:52332
db: ChEBI

Compound/PW C000096/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ethanolamine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Choline-phosphate cytidylyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q9ZV56

Choline/ethanolamine kinase
type: ProteinReference
xref: Reference/UniProt Q9M9H6

Serine decarboxylase
type: ProteinReference
xref: Reference/UniProt Q9MA74

Phosphoethanolamine/phosphocholine phosphatase
type: ProteinReference
xref: Reference/UniProt Q9FZ62

Phosphoethanolamine N-methyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q9FR44

PE-NMe2(20:0/20:1(11Z))
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: PE-NMe2(20:0/20:1(11Z))

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Compound/PW C059092/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-N-dimethylethanolamine
stoichiometric coefficient: 1.0

Reference/ChemSpider 388301
type: UnificationXref
id: 388301
db: ChemSpider

S-Adenosylhomocysteine
type: SmallMolecule
entity reference: S-Adenosylhomocysteine

Phospholipase D alpha
type: ProteinReference
xref: Reference/UniProt Q38882

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00021
type: UnificationXref
id: C00021
db: KEGG Compound

Compound/PW C000921/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylmethionine
stoichiometric coefficient: 1.0

Reference/BioCyc PHOSPHORYL-CHOLINE
type: UnificationXref
id: PHOSPHORYL-CHOLINE
db: BioCyc

Reference/BioCyc DIACYLGLYCEROL
type: UnificationXref
id: DIACYLGLYCEROL
db: BioCyc

Reference/KEGG Compound C00157
type: UnificationXref
id: C00157
db: KEGG Compound

Reference/HMDB HMDB0112524
type: UnificationXref
id: HMDB0112524
db: HMDB

Water
type: SmallMolecule
entity reference: Water

PE-NMe(20:0/20:1(11Z))
type: SmallMolecule
entity reference: PE-NMe(20:0/20:1(11Z))

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/KEGG Compound C13482
type: UnificationXref
id: C13482
db: KEGG Compound

Reference/KEGG Compound C00165
type: UnificationXref
id: C00165
db: KEGG Compound

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000065
type: ChemicalStructure
structure format: SMILES
structure data: C[N+](C)(C)CCO

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000149
type: UnificationXref
id: HMDB0000149
db: HMDB

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Reference/PubChem-compound 305
type: UnificationXref
id: 305
db: PubChem-compound

Reference/ChEBI CHEBI 18132
type: UnificationXref
id: CHEBI:18132
db: ChEBI

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

ChemicalStructure/PW C000149
type: ChemicalStructure
structure format: SMILES
structure data: NCCOP(O)(O)=O

Reference/ChEBI CHEBI 57781
type: UnificationXref
id: CHEBI:57781
db: ChEBI

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Phosphatidyl-N-methylethanolamine N-methyltransferase
type: ProteinReference
xref: Reference/UniProt Q9SAH5

Phosphatidylserine decarboxylase proenzyme 3
type: ProteinReference
xref: Reference/UniProt A4GNA8

ChemicalStructure/PW C003420
type: ChemicalStructure
structure format: SMILES

Non-specific phospholipase C4
type: ProteinReference
xref: Reference/UniProt Q9SRQ7

Choline/ethanolaminephosphotransferase 1
type: ProteinReference
xref: Reference/UniProt O82567

Ethanolamine-phosphate cytidylyltransferase
type: ProteinReference
xref: Reference/UniProt Q9ZVI9

Reference/UniProt Q9ZV56
type: UnificationXref
id: Q9ZV56
db: UniProt

Reference/KEGG Compound C04308
type: UnificationXref
id: C04308
db: KEGG Compound

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/ChEBI CHEBI 58641
type: UnificationXref
id: CHEBI:58641
db: ChEBI

Reference/KEGG Compound C00065
type: UnificationXref
id: C00065
db: KEGG Compound

Compound/PW C057892/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Methylethanolamine phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00189
type: UnificationXref
id: C00189
db: KEGG Compound

Reference/CAS 107-73-3
type: UnificationXref
id: 107-73-3
db: CAS

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChemSpider 31983
type: UnificationXref
id: 31983
db: ChemSpider

Compound/PW C003420/Stoichiometry/1.0
type: Stoichiometry
physical entity: DG(20:0/20:1(11Z)/0:0)
stoichiometric coefficient: 1.0

Phosphatidylcholine Biosynthesis PC(20:0/20:1(11Z))
type: Pathway
pathway order: PathwayEnzymeReaction/1197879
pathway order: PathwayEnzymeReaction/1197878
pathway order: PathwayEnzymeReaction/1197877
pathway order: PathwayEnzymeReaction/1197876
pathway order: PathwayTransport/1197859
pathway order: PathwayEnzymeReaction/1197875
pathway order: PathwayEnzymeReaction/1197874
pathway order: PathwayEnzymeReaction/1197873
pathway order: PathwayEnzymeReaction/1197872
pathway order: PathwayEnzymeReaction/1197871
pathway order: PathwayEnzymeReaction/1197870
pathway order: PathwayTransport/1197856
pathway order: PathwayTransport/1197853
pathway order: PathwayEnzymeReaction/1197869
pathway order: PathwayEnzymeReaction/1197868
pathway order: PathwayEnzymeReaction/1197867
pathway order: PathwayEnzymeReaction/1197866
pathway order: PathwayEnzymeReaction/1197887
pathway order: PathwayEnzymeReaction/1197886
pathway order: PathwayEnzymeReaction/1197885
pathway order: PathwayEnzymeReaction/1197884
pathway order: PathwayEnzymeReaction/1197883
pathway order: PathwayEnzymeReaction/1197882
pathway order: PathwayEnzymeReaction/1197881
pathway order: PathwayEnzymeReaction/1197880
pathway order: PathwayTransport/1197846
pathway component: Transport1476
pathway component: Transport1475
pathway component: ReactionCatalysis39985
pathway component: 4.1.1.-
pathway component: ReactionCatalysis39989
pathway component: Transport1474
pathway component: 2.7.1.82
pathway component: 2.7.7.-
pathway component: ReactionCatalysis39986
pathway component: Transport1473
pathway component: 2.1.1.103
pathway component: 2.7.7.57
pathway component: Reaction47487
pathway component: 3.1.3.75
pathway component: 2.7.7.15
pathway component: Reaction49849
pathway component: Reaction111676
pathway component: ReactionCatalysis37636
pathway component: Reaction111675
pathway component: ReactionCatalysis39979
pathway component: Reaction111679
pathway component: Reaction111678
pathway component: Reaction111677
pathway component: ReactionCatalysis39995
pathway component: ReactionCatalysis39974
pathway component: ReactionCatalysis39996
pathway component: ReactionCatalysis37631
pathway component: ReactionCatalysis39993
pathway component: ReactionCatalysis37630
pathway component: ReactionCatalysis39994
pathway component: ReactionCatalysis37633
pathway component: ReactionCatalysis39999
pathway component: ReactionCatalysis37632
pathway component: ReactionCatalysis37635
pathway component: ReactionCatalysis39997
pathway component: ReactionCatalysis37634
pathway component: ReactionCatalysis39998
pathway component: 2.7.7.14
pathway component: ReactionCatalysis39991
pathway component: ReactionCatalysis39992
pathway component: ReactionCatalysis39990
pathway component: 2.7.8.2
pathway component: 2.7.8.-
pathway component: Reaction111680
pathway component: Reaction111685
pathway component: Reaction111684
xref: Reference/PathWhiz PW064890
xref: Reference/SMPDB SMP0063882
organism: Arabidopsis thaliana

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/PathWhiz PW064890
type: UnificationXref
id: PW064890
db: PathWhiz

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ChemicalStructure/PW C000096
type: ChemicalStructure
structure format: SMILES
structure data: NCCO

CDP-ethanolamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001564
xref: Reference/ChEBI CHEBI 16732
xref: Reference/PubChem-compound 123727
xref: Reference/CAS 3036-18-8
xref: Reference/BioCyc CDP-ETHANOLAMINE
xref: Reference/KEGG Compound C00570
xref: Reference/ChemSpider 110296
chemical formula: C11H20N4O11P2
molecular weight: 446.0604
structure: ChemicalStructure/PW C001201

Phosphorylcholine
type: SmallMoleculeReference
xref: Reference/CAS 107-73-3
xref: Reference/HMDB HMDB0001565
xref: Reference/BioCyc PHOSPHORYL-CHOLINE
xref: Reference/PubChem-compound 1014
xref: Reference/ChEBI CHEBI 18132
xref: Reference/KEGG Compound C00588
xref: Reference/ChemSpider 989
chemical formula: C5H15NO4P
molecular weight: 184.07387
structure: ChemicalStructure/PW C001202

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/UniProt Q9FZ62
type: UnificationXref
id: Q9FZ62
db: UniProt

Reference/HMDB HMDB0060244
type: UnificationXref
id: HMDB0060244
db: HMDB

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

N-Methylethanolamine phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 25201132
xref: Reference/KEGG Compound C01210
xref: Reference/ChEBI CHEBI 57781
xref: Reference/BioCyc CPD-406
chemical formula: C3H9NO4P
molecular weight: 154.02747
structure: ChemicalStructure/PW C057892

N-Dimethylethanolamine phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0060244
xref: Reference/KEGG Compound C13482
xref: Reference/PubChem-compound 25201906
xref: Reference/ChEBI CHEBI 58641
xref: Reference/BioCyc CPD-5441
chemical formula: C4H11NO4P
molecular weight: 168.04312
structure: ChemicalStructure/PW C057893

PS(20:0/20:1(11Z))
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0112524
xref: Reference/ChEBI CHEBI 18303
xref: Reference/ChemSpider 13628254
xref: Reference/BioCyc L-1-PHOSPHATIDYL-SERINE
xref: Reference/KEGG Compound C02737
xref: Reference/PubChem-compound 6323481
chemical formula: C46H88NO10P
molecular weight: 845.61456
structure: ChemicalStructure/PW C060934

Reference/PubChem-compound 123727
type: UnificationXref
id: 123727
db: PubChem-compound

Compound/PW C062494/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

L-Serine
type: SmallMolecule
entity reference: L-Serine

L-Serine
type: SmallMoleculeReference
xref: Reference/ChemSpider 5736
xref: Reference/ChEBI CHEBI 17115
xref: Reference/CAS 56-45-1
xref: Reference/KEGG Compound C00065
xref: Reference/PubChem-compound 5951
xref: Reference/HMDB HMDB0000187
xref: Reference/BioCyc SER
chemical formula: C3H7NO3
molecular weight: 105.042595
structure: ChemicalStructure/PW C000120

Reference/HMDB HMDB0000187
type: UnificationXref
id: HMDB0000187
db: HMDB

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

N-Dimethylethanolamine phosphate
type: SmallMolecule
entity reference: N-Dimethylethanolamine phosphate

N-Methylethanolamine phosphate
type: SmallMolecule
entity reference: N-Methylethanolamine phosphate

Phosphorylcholine
type: SmallMolecule
entity reference: Phosphorylcholine

Reference/KEGG Compound C03486
type: UnificationXref
id: C03486
db: KEGG Compound

Compound/PW C005278/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Reference/PubChem-compound 25246222
type: UnificationXref
id: 25246222
db: PubChem-compound

Compound/PW C060934/Stoichiometry/1.0
type: Stoichiometry
physical entity: PS(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

CDP-ethanolamine
type: SmallMolecule
entity reference: CDP-ethanolamine

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/ChemSpider 990
type: UnificationXref
id: 990
db: ChemSpider

Reference/ChEBI CHEBI 65117
type: UnificationXref
id: CHEBI:65117
db: ChEBI

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/CAS 62-49-7
type: UnificationXref
id: 62-49-7
db: CAS

Reference/ChemSpider 989
type: UnificationXref
id: 989
db: ChemSpider

Reference/BioCyc CPD-160
type: UnificationXref
id: CPD-160
db: BioCyc

ChemicalStructure/PW C004323
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

CDP-Choline
type: SmallMolecule
entity reference: CDP-Choline

ChemicalStructure/PW C060211
type: ChemicalStructure
structure format: SMILES

CDP-Choline
type: SmallMoleculeReference
xref: Reference/BioCyc CDP-CHOLINE
xref: Reference/ChemSpider 13207
xref: Reference/HMDB HMDB0001413
xref: Reference/ChEBI CHEBI 16436
xref: Reference/KEGG Compound C00307
xref: Reference/PubChem-compound 11583971
xref: Reference/CAS 987-78-0
chemical formula: C14H26N4O11P2
molecular weight: 488.10733
structure: ChemicalStructure/PW C043034

O-Phosphoethanolamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000224
xref: Reference/BioCyc PHOSPHORYL-ETHANOLAMINE
xref: Reference/ChemSpider 990
xref: Reference/PubChem-compound 1015
xref: Reference/KEGG Compound C00346
xref: Reference/ChEBI CHEBI 17553
xref: Reference/CAS 1071-23-4
chemical formula: C2H8NO4P
molecular weight: 141.01909
structure: ChemicalStructure/PW C000149

Reference/BioCyc PHOSPHORYL-ETHANOLAMINE
type: UnificationXref
id: PHOSPHORYL-ETHANOLAMINE
db: BioCyc

Reference/TAXONOMY 3702
type: UnificationXref
id: 3702
db: TAXONOMY

Reference/PubChem-compound 14152391
type: UnificationXref
id: 14152391
db: PubChem-compound

Reference/PubChem-compound 1014
type: UnificationXref
id: 1014
db: PubChem-compound

Reference/PubChem-compound 1015
type: UnificationXref
id: 1015
db: PubChem-compound

DG(20:0/20:1(11Z)/0:0)
type: SmallMoleculeReference
xref: Reference/BioCyc DIACYLGLYCEROL
xref: Reference/KEGG Compound C00165
xref: Reference/HMDB HMDB0007369
xref: Reference/ChemSpider 7822743
xref: Reference/PubChem-compound 9543793
chemical formula: C43H82O5
molecular weight: 678.6162
structure: ChemicalStructure/PW C003420

Reference/BioCyc L-1-PHOSPHATIDYL-ETHANOLAMINE
type: UnificationXref
id: L-1-PHOSPHATIDYL-ETHANOLAMINE
db: BioCyc

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/ChEBI CHEBI 15958
type: UnificationXref
id: CHEBI:15958
db: ChEBI

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Reference/HMDB HMDB0009230
type: UnificationXref
id: HMDB0009230
db: HMDB

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/PubChem-compound 24779042
type: UnificationXref
id: 24779042
db: PubChem-compound

Reference/KEGG Compound C01241
type: UnificationXref
id: C01241
db: KEGG Compound

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

PE-NMe2(20:0/20:1(11Z))
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0114194
xref: Reference/KEGG Compound C04308
xref: Reference/BioCyc CPD-160
xref: Reference/ChEBI CHEBI 52332
chemical formula: C47H92NO8P
molecular weight: 829.65607
structure: ChemicalStructure/PW C060211

Reference/BioCyc CDP-ETHANOLAMINE
type: UnificationXref
id: CDP-ETHANOLAMINE
db: BioCyc

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/HMDB HMDB0008275
type: UnificationXref
id: HMDB0008275
db: HMDB

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

DG(20:0/20:1(11Z)/0:0)
type: SmallMolecule
entity reference: DG(20:0/20:1(11Z)/0:0)

ChemicalStructure/PW C059416
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/SMPDB SMP0063882
type: UnificationXref
id: SMP0063882
db: SMPDB

Non-specific phospholipase C4
type: Protein
entity reference: Non-specific phospholipase C4

Reference/BioCyc CPD-405
type: UnificationXref
id: CPD-405
db: BioCyc

Ethanolamine-phosphate cytidylyltransferase
type: Protein
entity reference: Ethanolamine-phosphate cytidylyltransferase

Phosphatidylserine decarboxylase proenzyme 3
type: Protein
entity reference: Phosphatidylserine decarboxylase proenzyme 3

Reference/BioCyc ADENOSYL-HOMO-CYS
type: UnificationXref
id: ADENOSYL-HOMO-CYS
db: BioCyc

Choline/ethanolaminephosphotransferase 1
type: Protein
entity reference: Choline/ethanolaminephosphotransferase 1

O-Phosphoethanolamine
type: SmallMolecule
entity reference: O-Phosphoethanolamine

Reference/CAS 485-80-3
type: UnificationXref
id: 485-80-3
db: CAS

Reference/PubChem-compound 25201132
type: UnificationXref
id: 25201132
db: PubChem-compound

Reference/BioCyc SER
type: UnificationXref
id: SER
db: BioCyc

Reference/HMDB HMDB0001413
type: UnificationXref
id: HMDB0001413
db: HMDB

Phosphatidyl-N-methylethanolamine N-methyltransferase
type: Protein
entity reference: Phosphatidyl-N-methylethanolamine N-methyltransferase

Reference/BioCyc CPD-406
type: UnificationXref
id: CPD-406
db: BioCyc

Reference/ChEBI CHEBI 16732
type: UnificationXref
id: CHEBI:16732
db: ChEBI

Compound/PW C005278 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Ethanolamine
type: SmallMolecule
entity reference: Ethanolamine

PE-NMe(20:0/20:1(11Z))
type: SmallMoleculeReference
xref: Reference/KEGG Compound C01241
xref: Reference/BioCyc CPD-405
xref: Reference/HMDB HMDB0113292
xref: Reference/ChEBI CHEBI 15958
chemical formula: C46H90NO8P
molecular weight: 815.6404
structure: ChemicalStructure/PW C059416

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

PC(20:0/20:1(11Z))
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: PC(20:0/20:1(11Z))

Reference/ChEBI CHEBI 15414
type: UnificationXref
id: CHEBI:15414
db: ChEBI

PE-NMe2(20:0/20:1(11Z))
type: SmallMolecule
entity reference: PE-NMe2(20:0/20:1(11Z))

Reference/BioCyc CPD-5441
type: UnificationXref
id: CPD-5441
db: BioCyc

PC(20:0/20:1(11Z))
type: SmallMolecule
entity reference: PC(20:0/20:1(11Z))

Reference/HMDB HMDB0000224
type: UnificationXref
id: HMDB0000224
db: HMDB

PC(20:0/20:1(11Z))
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0008275
xref: Reference/ChemSpider 24766936
xref: Reference/PubChem-compound 24779042
xref: Reference/KEGG Compound C00157
xref: Reference/BioCyc PHOSPHATIDYLCHOLINE
chemical formula: C48H94NO8P
molecular weight: 843.6717
structure: ChemicalStructure/PW C004323

Reference/ChemSpider 13835336
type: UnificationXref
id: 13835336
db: ChemSpider

Compound/PW C059416 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE-NMe(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

ChemicalStructure/PW C043034
type: ChemicalStructure
structure format: SMILES

Compound/PW C000120/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Serine
stoichiometric coefficient: 1.0

Compound/PW C059416 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE-NMe(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Reference/BioCyc S-ADENOSYLMETHIONINE
type: UnificationXref
id: S-ADENOSYLMETHIONINE
db: BioCyc

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/PubChem-compound 5951
type: UnificationXref
id: 5951
db: PubChem-compound

Reference/HMDB HMDB0001564
type: UnificationXref
id: HMDB0001564
db: HMDB

Compound/PW C059416/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE-NMe(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Reference/HMDB HMDB0001565
type: UnificationXref
id: HMDB0001565
db: HMDB

Compound/PW C001202/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphorylcholine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001202
type: ChemicalStructure
structure format: SMILES
structure data: C[N+](C)(C)CCOP(O)(O)=O

ChemicalStructure/PW C001201
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Reference/BioCyc CPD-563
type: UnificationXref
id: CPD-563
db: BioCyc

Compound/PW C060211/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE-NMe2(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Cytidine monophosphate
type: SmallMolecule
entity reference: Cytidine monophosphate

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

ChemicalStructure/PW C000120
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CO)C(O)=O

Reference/UniProt Q9ZVI9
type: UnificationXref
id: Q9ZVI9
db: UniProt

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Choline
type: SmallMolecule
entity reference: Choline

Reference/ChEBI CHEBI 15868
type: UnificationXref
id: CHEBI:15868
db: ChEBI

Choline
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15354
xref: Reference/ChemSpider 299
xref: Reference/BioCyc CPD-563
xref: Reference/PubChem-compound 305
xref: Reference/CAS 62-49-7
xref: Reference/HMDB HMDB0000097
xref: Reference/KEGG Compound C00114
chemical formula: C5H14NO
molecular weight: 104.10754
structure: ChemicalStructure/PW C000065

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

Reference/HMDB HMDB0113292
type: UnificationXref
id: HMDB0113292
db: HMDB

CDP-N-dimethylethanolamine
type: SmallMolecule
entity reference: CDP-N-dimethylethanolamine

CDP-N-methylethanolamine
type: SmallMolecule
entity reference: CDP-N-methylethanolamine

Endoplasmic Reticulum
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005783

PC(20:0/20:1(11Z))
type: SmallMolecule
cellular location: Cytoplasm
entity reference: PC(20:0/20:1(11Z))

Compound/PW C060211 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE-NMe2(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Reference/UniProt O82567
type: UnificationXref
id: O82567
db: UniProt

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/PubChem-compound 9543793
type: UnificationXref
id: 9543793
db: PubChem-compound

Reference/HMDB HMDB0000939
type: UnificationXref
id: HMDB0000939
db: HMDB

Reference/BioCyc CDP-N-METHYLETHANOLAMIN
type: UnificationXref
id: CDP-N-METHYLETHANOLAMIN
db: BioCyc

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

PA(20:0/20:1(11Z))
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
xref: Reference/HMDB HMDB0115076
chemical formula: C43H83O8P
molecular weight: 758.5826
structure: ChemicalStructure/PW C062494

Reference/PubChem-compound 9546851
type: UnificationXref
id: 9546851
db: PubChem-compound

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

2.7.7.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059092/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057893/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: CDP-N-dimethylethanolamine
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.-
left: Cytidine triphosphate
left: Hydrogen Ion
left: N-Dimethylethanolamine phosphate
name: Cytidine triphosphate + Hydrogen Ion + N-Dimethylethanolamine phosphate → CDP-N-dimethylethanolamine + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

2.7.7.57
type: BiochemicalReaction
participant stoichiometry: Compound/PW C059090/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057892/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: CDP-N-methylethanolamine
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.57
left: Cytidine triphosphate
left: Hydrogen Ion
left: N-Methylethanolamine phosphate
name: Cytidine triphosphate + Hydrogen Ion + N-Methylethanolamine phosphate → CDP-N-methylethanolamine + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Arabidopsis thaliana
type: BioSource
xref: Reference/TAXONOMY 3702

Compound/PW C004323 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: PC(20:0/20:1(11Z))
stoichiometric coefficient: 1.0

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/BioCyc ETHANOL-AMINE
type: UnificationXref
id: ETHANOL-AMINE
db: BioCyc

Reference/GENE ONTOLOGY GO 0005783
type: UnificationXref
id: GO:0005783
db: GENE ONTOLOGY

Ethanolamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000149
xref: Reference/ChemSpider 13835336
xref: Reference/PubChem-compound 700
xref: Reference/CAS 141-43-5
xref: Reference/BioCyc ETHANOL-AMINE
xref: Reference/ChEBI CHEBI 16000
xref: Reference/KEGG Compound C00189
chemical formula: C2H7NO
molecular weight: 61.052765
structure: ChemicalStructure/PW C000096

PA(20:0/20:1(11Z))
type: SmallMolecule
entity reference: PA(20:0/20:1(11Z))

CDP-N-dimethylethanolamine
type: SmallMoleculeReference
xref: Reference/BioCyc CPD4FS-1
xref: Reference/PubChem-compound 14152391
xref: Reference/ChEBI CHEBI 65117
chemical formula: C13H24N4O11P2
molecular weight: 474.09167
structure: ChemicalStructure/PW C059092

Reference/ChemSpider 13628254
type: UnificationXref
id: 13628254
db: ChemSpider

Compound/PW C001201/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-ethanolamine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

ChemicalStructure/PW C057892
type: ChemicalStructure
structure format: SMILES
structure data: CNCCOP(O)([O-])=O

ChemicalStructure/PW C057893
type: ChemicalStructure
structure format: SMILES
structure data: CN(C)CCOP(O)([O-])=O

Reference/CAS 3036-18-8
type: UnificationXref
id: 3036-18-8
db: CAS

ChemicalStructure/PW C060934
type: ChemicalStructure
structure format: SMILES

PE-NMe2(20:0/20:1(11Z))
type: SmallMolecule
cellular location: Cytoplasm
entity reference: PE-NMe2(20:0/20:1(11Z))

Reference/CAS 987-78-0
type: UnificationXref
id: 987-78-0
db: CAS

CDP-N-methylethanolamine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440026
xref: Reference/BioCyc CDP-N-METHYLETHANOLAMIN
xref: Reference/ChEBI CHEBI 15868
xref: Reference/KEGG Compound C03486
chemical formula: C12H22N4O11P2
molecular weight: 460.07602
structure: ChemicalStructure/PW C059090

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reaction49849
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001202/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000065/Stoichiometry/1.0
right: Adenosine diphosphate
right: Phosphorylcholine
spontaneous: false
left: Choline
left: Adenosine triphosphate
name: Adenosine triphosphate + Choline → Adenosine diphosphate + Phosphorylcholine
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 299
type: UnificationXref
id: 299
db: ChemSpider

Reference/HMDB HMDB0007369
type: UnificationXref
id: HMDB0007369
db: HMDB

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/UniProt Q38882
type: UnificationXref
id: Q38882
db: UniProt

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/BioCyc L-1-PHOSPHATIDYL-SERINE
type: UnificationXref
id: L-1-PHOSPHATIDYL-SERINE
db: BioCyc

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/CAS 56-45-1
type: UnificationXref
id: 56-45-1
db: CAS

2.7.7.14
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001201/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000149/Stoichiometry/1.0
right: CDP-ethanolamine
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.14
left: Cytidine triphosphate
left: O-Phosphoethanolamine
name: Cytidine triphosphate + O-Phosphoethanolamine → CDP-ethanolamine + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt A4GNA8
type: UnificationXref
id: A4GNA8
db: UniProt

Reference/ChEBI CHEBI 17553
type: UnificationXref
id: CHEBI:17553
db: ChEBI

S-Adenosylmethionine
type: SmallMolecule
entity reference: S-Adenosylmethionine

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/PubChem-compound 11583971
type: UnificationXref
id: 11583971
db: PubChem-compound

Reference/UniProt Q9SRQ7
type: UnificationXref
id: Q9SRQ7
db: UniProt

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/ChEBI CHEBI 16436
type: UnificationXref
id: CHEBI:16436
db: ChEBI

Phospholipase D alpha
type: Protein
entity reference: Phospholipase D alpha

PE-NMe(20:0/20:1(11Z))
type: SmallMolecule
cellular location: Cytoplasm
entity reference: PE-NMe(20:0/20:1(11Z))

ChemicalStructure/PW C000749
type: ChemicalStructure
structure format: SMILES

Compound/PW C000749/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylhomocysteine
stoichiometric coefficient: 1.0

Choline/ethanolamine kinase
type: Protein
entity reference: Choline/ethanolamine kinase

Phosphoethanolamine N-methyltransferase 1
type: Protein
entity reference: Phosphoethanolamine N-methyltransferase 1

Reference/ChEBI CHEBI 15354
type: UnificationXref
id: CHEBI:15354
db: ChEBI

Phosphoethanolamine/phosphocholine phosphatase
type: Protein
entity reference: Phosphoethanolamine/phosphocholine phosphatase

Choline-phosphate cytidylyltransferase 1
type: Protein
entity reference: Choline-phosphate cytidylyltransferase 1

Reference/UniProt Q9FR44
type: UnificationXref
id: Q9FR44
db: UniProt

Reference/CAS 141-43-5
type: UnificationXref
id: 141-43-5
db: CAS

Reference/KEGG Compound C00307
type: UnificationXref
id: C00307
db: KEGG Compound

Serine decarboxylase
type: Protein
entity reference: Serine decarboxylase

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChEBI CHEBI 16680
type: UnificationXref
id: CHEBI:16680
db: ChEBI

Reference/PubChem-compound 24762165
type: UnificationXref
id: 24762165
db: PubChem-compound