1-Acyl-sn-glycerol-3-phosphate acyltransferase beta
type: Protein
entity reference: 1-Acyl-sn-glycerol-3-phosphate acyltransferase beta

LPA(15:0/0:0)
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: LPA(15:0/0:0)

Reference/PubChem-compound 3082227
type: UnificationXref
id: 3082227
db: PubChem-compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

TG(15:0/16:0/24:0)
type: SmallMolecule
entity reference: TG(15:0/16:0/24:0)

NADH
type: SmallMolecule
entity reference: NADH

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0043023
type: UnificationXref
id: HMDB0043023
db: HMDB

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Transport1560
type: Transport
participant stoichiometry: Compound/PW C055364 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055364 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: LPA(15:0/0:0)
spontaneous: false
left: LPA(15:0/0:0)
name: LPA(15:0/0:0) (→) Transport: Mus musculus, Cell, Mitochondrial Outer Membrane to Mus musculus, Cell, Endoplasmic Reticulum Membrane
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C062921
type: ChemicalStructure
structure format: SMILES

NAD
type: SmallMolecule
entity reference: NAD

Phosphatidate phosphatase LPIN1
type: Protein
entity reference: Phosphatidate phosphatase LPIN1

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Reference/HMDB HMDB0006526
type: UnificationXref
id: HMDB0006526
db: HMDB

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc PALMITYL-COA
type: UnificationXref
id: PALMITYL-COA
db: BioCyc

Diacylglycerol O-acyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q9Z2A7

Reference/TAXONOMY 10090
type: UnificationXref
id: 10090
db: TAXONOMY

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Tetracosanoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 24305-30-4
xref: Reference/ChEBI CHEBI 52974
xref: Reference/PubChem-compound 3082227
xref: Reference/HMDB HMDB0006526
xref: Reference/KEGG Compound C16529
chemical formula: C45H82N7O17P3S
molecular weight: 1117.4701
structure: ChemicalStructure/PW C002794

Reference/PubChem-compound 14275229
type: UnificationXref
id: 14275229
db: PubChem-compound

Reaction112866
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002794/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003120/Stoichiometry/1.0
participant stoichiometry: Compound/PW C023737/Stoichiometry/1.0
right: Coenzyme A
right: TG(15:0/16:0/24:0)
spontaneous: false
left: Tetracosanoyl-CoA
left: DG(15:0/16:0/0:0)
name: DG(15:0/16:0/0:0) + Tetracosanoyl-CoA → Coenzyme A + TG(15:0/16:0/24:0)
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/HMDB HMDB0007069
type: UnificationXref
id: HMDB0007069
db: HMDB

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

Glycerol-3-phosphate acyltransferase 1, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q61586

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

LPA(15:0/0:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: LPA(15:0/0:0)

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/PathWhiz PW065805
type: UnificationXref
id: PW065805
db: PathWhiz

Mus musculus
type: BioSource
xref: Reference/TAXONOMY 10090

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Reference/UniProt Q91ZP3
type: UnificationXref
id: Q91ZP3
db: UniProt

Phosphatidate phosphatase LPIN1
type: ProteinReference
xref: Reference/UniProt Q91ZP3

Reference/BioCyc CPD-14724
type: UnificationXref
id: CPD-14724
db: BioCyc

Reference/ChemSpider 24765902
type: UnificationXref
id: 24765902
db: ChemSpider

Reference/ChEBI CHEBI 16975
type: UnificationXref
id: CHEBI:16975
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Compound/PW C001031/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmityl-CoA
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15525
type: UnificationXref
id: CHEBI:15525
db: ChEBI

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

ChemicalStructure/PW C055364
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCC(=O)OCC(O)COP(O)(O)=O

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

DG(15:0/16:0/0:0)
type: SmallMolecule
entity reference: DG(15:0/16:0/0:0)

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

ChemicalStructure/PW C002794
type: ChemicalStructure
structure format: SMILES

Reaction112841
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003120/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055638/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: DG(15:0/16:0/0:0)
right: Phosphate
spontaneous: false
left: Water
left: PA(15:0/16:0)
name: PA(15:0/16:0) + Water → DG(15:0/16:0/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Reaction112840
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001031/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055364/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055638/Stoichiometry/1.0
right: Coenzyme A
right: PA(15:0/16:0)
spontaneous: false
left: Palmityl-CoA
left: LPA(15:0/0:0)
name: LPA(15:0/0:0) + Palmityl-CoA → Coenzyme A + PA(15:0/16:0)
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Compound/PW C055364 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(15:0/0:0)
stoichiometric coefficient: 1.0

TG(15:0/16:0/24:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0043023
chemical formula: C58H112O6
molecular weight: 904.8459
structure: ChemicalStructure/PW C023737

Compound/PW C002794/Stoichiometry/1.0
type: Stoichiometry
physical entity: Tetracosanoyl-CoA
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/CAS 1763-10-6
type: UnificationXref
id: 1763-10-6
db: CAS

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

Reference/ChEBI CHEBI 74574
type: UnificationXref
id: CHEBI:74574
db: ChEBI

1-Acyl-sn-glycerol-3-phosphate acyltransferase beta
type: ProteinReference
xref: Reference/UniProt Q8K3K7

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

De Novo Triacylglycerol Biosynthesis TG(15:0/16:0/24:0)
type: Pathway
pathway order: PathwayEnzymeReaction/1213631
pathway order: PathwayEnzymeReaction/1213630
pathway order: PathwayEnzymeReaction/1213632
pathway order: PathwaySubPathway/58787
pathway order: PathwayEnzymeReaction/1213628
pathway order: PathwayTransport/1213627
pathway order: PathwayEnzymeReaction/1213629
pathway component: Reaction110716
pathway component: Glycolysis
pathway component: Transport1560
pathway component: ReactionCatalysis102030
pathway component: ReactionCatalysis102031
pathway component: ReactionCatalysis101050
pathway component: Reaction112841
pathway component: ReactionCatalysis102032
pathway component: Reaction112840
pathway component: ReactionCatalysis102033
pathway component: Reaction112866
pathway component: Reaction112810
xref: Reference/PathWhiz PW065805
xref: Reference/SMPDB SMP0064795
organism: Mus musculus

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/UniProt Q9Z2A7
type: UnificationXref
id: Q9Z2A7
db: UniProt

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Reference/PubChem-compound 71581247
type: UnificationXref
id: 71581247
db: PubChem-compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

PA(15:0/16:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
chemical formula: C34H67O8P
molecular weight: 634.45734
structure: ChemicalStructure/PW C055638

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Reference/GENE ONTOLOGY GO 0005741
type: UnificationXref
id: GO:0005741
db: GENE ONTOLOGY

PA(15:0/16:0)
type: SmallMolecule
entity reference: PA(15:0/16:0)

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway58787
pathway component: SubPathwayInteraction58787
xref: Reference/PathWhiz PW064440
xref: Reference/SMPDB SMP0063478
name: SubPathway

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/UniProt Q61586
type: UnificationXref
id: Q61586
db: UniProt

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Palmityl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 15667
xref: Reference/ChemSpider 14902
xref: Reference/HMDB HMDB0001338
xref: Reference/ChEBI CHEBI 15525
xref: Reference/KEGG Compound C00154
xref: Reference/CAS 1763-10-6
xref: Reference/BioCyc PALMITYL-COA
chemical formula: C37H66N7O17P3S
molecular weight: 1005.34485
structure: ChemicalStructure/PW C001031

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

Palmityl-CoA
type: SmallMolecule
entity reference: Palmityl-CoA

Reference/HMDB HMDB0001338
type: UnificationXref
id: HMDB0001338
db: HMDB

SubPathwayInteraction58787
type: Interaction
name: SubPathwayReaction
name: SubPathway58787Reaction
participant: Dihydroxyacetone phosphate

Compound/PW C055364 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(15:0/0:0)
stoichiometric coefficient: 1.0

Mitochondrial Outer Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005741

Reference/UniProt P13707
type: UnificationXref
id: P13707
db: UniProt

Reference/BioCyc DIACYLGLYCEROL
type: UnificationXref
id: DIACYLGLYCEROL
db: BioCyc

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Endoplasmic Reticulum Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005789

Reference/KEGG Compound C00154
type: UnificationXref
id: C00154
db: KEGG Compound

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/KEGG Compound C00165
type: UnificationXref
id: C00165
db: KEGG Compound

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

ChemicalStructure/PW C001031
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reaction112810
type: BiochemicalReaction
participant stoichiometry: Compound/PW C062921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055364/Stoichiometry/1.0
right: Coenzyme A
right: LPA(15:0/0:0)
spontaneous: false
left: Pentadecanoyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Pentadecanoyl-CoA → Coenzyme A + LPA(15:0/0:0)
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 14902
type: UnificationXref
id: 14902
db: ChemSpider

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Pentadecanoyl-CoA
type: SmallMolecule
entity reference: Pentadecanoyl-CoA

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C055638/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(15:0/16:0)
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

DG(15:0/16:0/0:0)
type: SmallMoleculeReference
xref: Reference/BioCyc DIACYLGLYCEROL
xref: Reference/ChemSpider 24765902
xref: Reference/PubChem-compound 14275229
xref: Reference/KEGG Compound C00165
xref: Reference/HMDB HMDB0007069
chemical formula: C34H66O5
molecular weight: 554.491
structure: ChemicalStructure/PW C003120

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/UniProt Q8K3K7
type: UnificationXref
id: Q8K3K7
db: UniProt

Pentadecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 74574
xref: Reference/BioCyc CPD-14724
xref: Reference/PubChem-compound 71581247
xref: Reference/HMDB HMDB0062518
chemical formula: C36H64N7O17P3S
molecular weight: 991.3292
structure: ChemicalStructure/PW C062921

Reference/GENE ONTOLOGY GO 0005789
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

Compound/PW C023737/Stoichiometry/1.0
type: Stoichiometry
physical entity: TG(15:0/16:0/24:0)
stoichiometric coefficient: 1.0

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/PathWhiz PW064440
type: UnificationXref
id: PW064440
db: PathWhiz

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Diacylglycerol O-acyltransferase 1
type: Protein
entity reference: Diacylglycerol O-acyltransferase 1

Glycerol-3-phosphate acyltransferase 1, mitochondrial
type: Protein
entity reference: Glycerol-3-phosphate acyltransferase 1, mitochondrial

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

Reference/KEGG Compound C16529
type: UnificationXref
id: C16529
db: KEGG Compound

Reference/SMPDB SMP0063478
type: UnificationXref
id: SMP0063478
db: SMPDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Protein/14072/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

ReactionCatalysis102030
type: Catalysis
controller: Glycerol-3-phosphate acyltransferase 1, mitochondrial
controlled: Reaction112810
control type: ACTIVATION

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Tetracosanoyl-CoA
type: SmallMolecule
entity reference: Tetracosanoyl-CoA

ChemicalStructure/PW C055638
type: ChemicalStructure
structure format: SMILES

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Complex
component stoichiometry: Protein/14072/Stoichiometry/2.0
component: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

ReactionCatalysis102031
type: Catalysis
controller: 1-Acyl-sn-glycerol-3-phosphate acyltransferase beta
controlled: Reaction112840
control type: ACTIVATION

Compound/PW C055364/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(15:0/0:0)
stoichiometric coefficient: 1.0

ReactionCatalysis102032
type: Catalysis
controller: Phosphatidate phosphatase LPIN1
controlled: Reaction112841
control type: ACTIVATION

ReactionCatalysis102033
type: Catalysis
controller: Diacylglycerol O-acyltransferase 1
controlled: Reaction112866
control type: ACTIVATION

ChemicalStructure/PW C003120
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/SMPDB SMP0064795
type: UnificationXref
id: SMP0064795
db: SMPDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reaction110716
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: NADH
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH → Glycerol 3-phosphate + NAD
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

ReactionCatalysis101050
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
controlled: Reaction110716
control type: ACTIVATION

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Compound/PW C003120/Stoichiometry/1.0
type: Stoichiometry
physical entity: DG(15:0/16:0/0:0)
stoichiometric coefficient: 1.0

LPA(15:0/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16975
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
chemical formula: C18H37O7P
molecular weight: 396.2277
structure: ChemicalStructure/PW C055364

Reference/CAS 24305-30-4
type: UnificationXref
id: 24305-30-4
db: CAS

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 15667
type: UnificationXref
id: 15667
db: PubChem-compound

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Compound/PW C062921/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pentadecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

LPA(15:0/0:0)
type: SmallMolecule
entity reference: LPA(15:0/0:0)

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: ProteinReference
xref: Reference/UniProt P13707

ChemicalStructure/PW C023737
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 52974
type: UnificationXref
id: CHEBI:52974
db: ChEBI

Reference/HMDB HMDB0062518
type: UnificationXref
id: HMDB0062518
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O