1-Acyl-sn-glycerol-3-phosphate acyltransferase beta
type: Protein
entity reference: 1-Acyl-sn-glycerol-3-phosphate acyltransferase beta

Reference/HMDB HMDB0007280
type: UnificationXref
id: HMDB0007280
db: HMDB

ChemicalStructure/PW C062932
type: ChemicalStructure
structure format: SMILES
structure data: CCCCC\C=C/C\C=C/C\C=C/CCCCC(=O)OCC(O)COP(O)(O)=O

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

NADH
type: SmallMolecule
entity reference: NADH

Reference/HMDB HMDB0006519
type: UnificationXref
id: HMDB0006519
db: HMDB

Compound/PW C033713/Stoichiometry/1.0
type: Stoichiometry
physical entity: TG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z))
stoichiometric coefficient: 1.0

Clupanodonoyl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 56928012
xref: Reference/ChEBI CHEBI 63541
xref: Reference/KEGG Compound C16166
xref: Reference/CAS 58346-00-2
xref: Reference/HMDB HMDB0006267
chemical formula: C43H68N7O17P3S
molecular weight: 1079.3605
structure: ChemicalStructure/PW C002694

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Transport1566
type: Transport
participant stoichiometry: Compound/PW C062932 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062932 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: LPA(18:3(6Z,9Z,12Z)/0:0)
spontaneous: false
left: LPA(18:3(6Z,9Z,12Z)/0:0)
name: LPA(18:3(6Z,9Z,12Z)/0:0) (→) Transport: Mus musculus, Cell, Mitochondrial Outer Membrane to Mus musculus, Cell, Endoplasmic Reticulum Membrane
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0053192
type: UnificationXref
id: HMDB0053192
db: HMDB

NAD
type: SmallMolecule
entity reference: NAD

Phosphatidate phosphatase LPIN1
type: Protein
entity reference: Phosphatidate phosphatase LPIN1

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Reference/KEGG Compound C03035
type: UnificationXref
id: C03035
db: KEGG Compound

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Reference/BioCyc GAMMA-LINOLENOYL-COA
type: UnificationXref
id: GAMMA-LINOLENOYL-COA
db: BioCyc

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/PubChem-compound 52922033
type: UnificationXref
id: 52922033
db: PubChem-compound

Diacylglycerol O-acyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q9Z2A7

Reference/TAXONOMY 10090
type: UnificationXref
id: 10090
db: TAXONOMY

PA(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z))
type: SmallMolecule
entity reference: PA(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z))

Stearidonoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0006519
xref: Reference/KEGG Compound C16163
xref: Reference/ChEBI CHEBI 63545
xref: Reference/PubChem-compound 52922033
chemical formula: C39H62N7O17P3S
molecular weight: 1025.3136
structure: ChemicalStructure/PW C002788

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Clupanodonoyl-CoA
type: SmallMolecule
entity reference: Clupanodonoyl-CoA

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reaction115330
type: BiochemicalReaction
participant stoichiometry: Compound/PW C033713/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003331/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002694/Stoichiometry/1.0
right: Coenzyme A
right: TG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z))
spontaneous: false
left: Clupanodonoyl-CoA
left: DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0)
name: Clupanodonoyl-CoA + DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0) → Coenzyme A + TG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z))
conversion direction: LEFT_TO_RIGHT

Reference/SMPDB SMP0066912
type: UnificationXref
id: SMP0066912
db: SMPDB

PA(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z))
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
xref: Reference/HMDB HMDB0114984
chemical formula: C39H63O8P
molecular weight: 690.4261
structure: ChemicalStructure/PW C062402

Compound/PW C062932 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(18:3(6Z,9Z,12Z)/0:0)
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Compound/PW C062932/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(18:3(6Z,9Z,12Z)/0:0)
stoichiometric coefficient: 1.0

ChemicalStructure/PW C002737
type: ChemicalStructure
structure format: SMILES

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

Glycerol-3-phosphate acyltransferase 1, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q61586

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 24766030
type: UnificationXref
id: 24766030
db: ChemSpider

TG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z))
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0053192
chemical formula: C61H94O6
molecular weight: 922.705
structure: ChemicalStructure/PW C033713

Mus musculus
type: BioSource
xref: Reference/TAXONOMY 10090

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Reference/UniProt Q91ZP3
type: UnificationXref
id: Q91ZP3
db: UniProt

Phosphatidate phosphatase LPIN1
type: ProteinReference
xref: Reference/UniProt Q91ZP3

Reference/ChEBI CHEBI 16975
type: UnificationXref
id: CHEBI:16975
db: ChEBI

LPA(18:3(6Z,9Z,12Z)/0:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: LPA(18:3(6Z,9Z,12Z)/0:0)

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

ChemicalStructure/PW C002788
type: ChemicalStructure
structure format: SMILES

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Reference/HMDB HMDB0114984
type: UnificationXref
id: HMDB0114984
db: HMDB

Reference/HMDB HMDB0114743
type: UnificationXref
id: HMDB0114743
db: HMDB

Compound/PW C062402/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z))
stoichiometric coefficient: 1.0

Reaction115314
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002788/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062402/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062932/Stoichiometry/1.0
right: Coenzyme A
right: PA(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z))
spontaneous: false
left: LPA(18:3(6Z,9Z,12Z)/0:0)
left: Stearidonoyl-CoA
name: LPA(18:3(6Z,9Z,12Z)/0:0) + Stearidonoyl-CoA → Coenzyme A + PA(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z))
conversion direction: LEFT_TO_RIGHT

Reaction115315
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062402/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003331/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0)
right: Phosphate
spontaneous: false
left: Water
left: PA(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z))
name: PA(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)) + Water → DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/PubChem-compound 56928012
type: UnificationXref
id: 56928012
db: PubChem-compound

Reference/CAS 58346-00-2
type: UnificationXref
id: 58346-00-2
db: CAS

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

ChemicalStructure/PW C033713
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@](COC(=O)CCCCC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CC)(COC(=O)CCCC\C=C/C\C=C/C\C=C/CCCCC)OC(=O)CCCC\C=C/C\C=C/C\C=C/C\C=C/CC

LPA(18:3(6Z,9Z,12Z)/0:0)
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: LPA(18:3(6Z,9Z,12Z)/0:0)

1-Acyl-sn-glycerol-3-phosphate acyltransferase beta
type: ProteinReference
xref: Reference/UniProt Q8K3K7

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

Compound/PW C002694/Stoichiometry/1.0
type: Stoichiometry
physical entity: Clupanodonoyl-CoA
stoichiometric coefficient: 1.0

Reference/KEGG Compound C16166
type: UnificationXref
id: C16166
db: KEGG Compound

Compound/PW C002788/Stoichiometry/1.0
type: Stoichiometry
physical entity: Stearidonoyl-CoA
stoichiometric coefficient: 1.0

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/KEGG Compound C16163
type: UnificationXref
id: C16163
db: KEGG Compound

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/UniProt Q9Z2A7
type: UnificationXref
id: Q9Z2A7
db: UniProt

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Reference/GENE ONTOLOGY GO 0005741
type: UnificationXref
id: GO:0005741
db: GENE ONTOLOGY

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway60904
pathway component: SubPathwayInteraction60904
xref: Reference/PathWhiz PW064440
xref: Reference/SMPDB SMP0063478
name: SubPathway

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/UniProt Q61586
type: UnificationXref
id: Q61586
db: UniProt

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0)
type: SmallMoleculeReference
xref: Reference/ChemSpider 24766030
xref: Reference/BioCyc DIACYLGLYCEROL
xref: Reference/HMDB HMDB0007280
xref: Reference/KEGG Compound C00165
xref: Reference/PubChem-compound 53478122
chemical formula: C39H62O5
molecular weight: 610.4597
structure: ChemicalStructure/PW C003331

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0)
type: SmallMolecule
entity reference: DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0)

Reference/ChEBI CHEBI 15508
type: UnificationXref
id: CHEBI:15508
db: ChEBI

Mitochondrial Outer Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005741

Reference/UniProt P13707
type: UnificationXref
id: P13707
db: UniProt

Reference/BioCyc DIACYLGLYCEROL
type: UnificationXref
id: DIACYLGLYCEROL
db: BioCyc

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Endoplasmic Reticulum Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005789

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Reference/PubChem-compound 11966132
type: UnificationXref
id: 11966132
db: PubChem-compound

ChemicalStructure/PW C062402
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@](COC(=O)CCCC\C=C/C\C=C/C\C=C/CCCCC)(COP(O)(O)=O)OC(=O)CCCC\C=C/C\C=C/C\C=C/C\C=C/CC

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/KEGG Compound C00165
type: UnificationXref
id: C00165
db: KEGG Compound

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

γ-Linolenoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 18172-33-3
xref: Reference/PubChem-compound 11966132
xref: Reference/BioCyc GAMMA-LINOLENOYL-COA
xref: Reference/ChemSpider 10140126
xref: Reference/HMDB HMDB0006368
xref: Reference/ChEBI CHEBI 15508
xref: Reference/KEGG Compound C03035
chemical formula: C39H64N7O17P3S
molecular weight: 1027.3292
structure: ChemicalStructure/PW C002737

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

ChemicalStructure/PW C003331
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@](CO)(COC(=O)CCCC\C=C/C\C=C/C\C=C/CCCCC)OC(=O)CCCC\C=C/C\C=C/C\C=C/C\C=C/CC

Reference/HMDB HMDB0006368
type: UnificationXref
id: HMDB0006368
db: HMDB

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/ChEBI CHEBI 63541
type: UnificationXref
id: CHEBI:63541
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

γ-Linolenoyl-CoA
type: SmallMolecule
entity reference: γ-Linolenoyl-CoA

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/CAS 18172-33-3
type: UnificationXref
id: 18172-33-3
db: CAS

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/UniProt Q8K3K7
type: UnificationXref
id: Q8K3K7
db: UniProt

Reference/GENE ONTOLOGY GO 0005789
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

ChemicalStructure/PW C002694
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

LPA(18:3(6Z,9Z,12Z)/0:0)
type: SmallMolecule
entity reference: LPA(18:3(6Z,9Z,12Z)/0:0)

Reference/PathWhiz PW064440
type: UnificationXref
id: PW064440
db: PathWhiz

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/PubChem-compound 53478122
type: UnificationXref
id: 53478122
db: PubChem-compound

Diacylglycerol O-acyltransferase 1
type: Protein
entity reference: Diacylglycerol O-acyltransferase 1

TG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z))
type: SmallMolecule
entity reference: TG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z))

Glycerol-3-phosphate acyltransferase 1, mitochondrial
type: Protein
entity reference: Glycerol-3-phosphate acyltransferase 1, mitochondrial

LPA(18:3(6Z,9Z,12Z)/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16975
xref: Reference/HMDB HMDB0114743
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
chemical formula: C21H37O7P
molecular weight: 432.2277
structure: ChemicalStructure/PW C062932

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

Reference/HMDB HMDB0006267
type: UnificationXref
id: HMDB0006267
db: HMDB

Reference/ChemSpider 10140126
type: UnificationXref
id: 10140126
db: ChemSpider

Reference/ChEBI CHEBI 63545
type: UnificationXref
id: CHEBI:63545
db: ChEBI

Reference/SMPDB SMP0063478
type: UnificationXref
id: SMP0063478
db: SMPDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Protein/14072/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
stoichiometric coefficient: 2.0

Compound/PW C002737/Stoichiometry/1.0
type: Stoichiometry
physical entity: γ-Linolenoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

ReactionCatalysis102030
type: Catalysis
controller: Glycerol-3-phosphate acyltransferase 1, mitochondrial
controlled: Reaction115265
control type: ACTIVATION

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Complex
component stoichiometry: Protein/14072/Stoichiometry/2.0
component: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

ReactionCatalysis102031
type: Catalysis
controller: 1-Acyl-sn-glycerol-3-phosphate acyltransferase beta
controlled: Reaction115314
control type: ACTIVATION

ReactionCatalysis102032
type: Catalysis
controller: Phosphatidate phosphatase LPIN1
controlled: Reaction115315
control type: ACTIVATION

ReactionCatalysis102033
type: Catalysis
controller: Diacylglycerol O-acyltransferase 1
controlled: Reaction115330
control type: ACTIVATION

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reaction110716
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: NADH
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH → Glycerol 3-phosphate + NAD
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

ReactionCatalysis101050
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
controlled: Reaction110716
control type: ACTIVATION

Compound/PW C003331/Stoichiometry/1.0
type: Stoichiometry
physical entity: DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0)
stoichiometric coefficient: 1.0

Stearidonoyl-CoA
type: SmallMolecule
entity reference: Stearidonoyl-CoA

Reference/PathWhiz PW067922
type: UnificationXref
id: PW067922
db: PathWhiz

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

De Novo Triacylglycerol Biosynthesis TG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z))
type: Pathway
pathway order: PathwayEnzymeReaction/1247483
pathway order: PathwayEnzymeReaction/1247485
pathway order: PathwayEnzymeReaction/1247484
pathway order: PathwayEnzymeReaction/1247487
pathway order: PathwayEnzymeReaction/1247486
pathway order: PathwaySubPathway/60904
pathway order: PathwayTransport/1247482
pathway component: Reaction110716
pathway component: Transport1566
pathway component: Glycolysis
pathway component: Reaction115330
pathway component: Reaction115265
pathway component: ReactionCatalysis102030
pathway component: ReactionCatalysis102031
pathway component: ReactionCatalysis101050
pathway component: ReactionCatalysis102032
pathway component: ReactionCatalysis102033
pathway component: Reaction115314
pathway component: Reaction115315
xref: Reference/PathWhiz PW067922
xref: Reference/SMPDB SMP0066912
organism: Mus musculus

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Compound/PW C062932 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(18:3(6Z,9Z,12Z)/0:0)
stoichiometric coefficient: 1.0

SubPathwayInteraction60904
type: Interaction
name: SubPathway60904Reaction
name: SubPathwayReaction
participant: Dihydroxyacetone phosphate

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: ProteinReference
xref: Reference/UniProt P13707

Reaction115265
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002737/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062932/Stoichiometry/1.0
right: Coenzyme A
right: LPA(18:3(6Z,9Z,12Z)/0:0)
spontaneous: false
left: γ-Linolenoyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + γ-Linolenoyl-CoA → Coenzyme A + LPA(18:3(6Z,9Z,12Z)/0:0)
conversion direction: LEFT_TO_RIGHT

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O