Compound/PW C003905/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(18:0/0:0)
stoichiometric coefficient: 1.0

Reference/ChemSpider 24765825
type: UnificationXref
id: 24765825
db: ChemSpider

Transport4048
type: Transport
participant stoichiometry: Compound/PW C055651 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055651 Mitochondrial Outer Membrane/Stoichiometry/1.0
right: PA(18:0/18:1(11Z))
spontaneous: false
left: PA(18:0/18:1(11Z))
name: PA(18:0/18:1(11Z)) (→) Transport: Bos taurus, Cell, Mitochondrial Outer Membrane to Bos taurus, Cell, Mitochondrial Inner Membrane
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Reference/UniProt Q5E9R2
type: UnificationXref
id: Q5E9R2
db: UniProt

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL-P
db: BioCyc

CL(18:0/18:1(11Z)/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05980
xref: Reference/HMDB HMDB0057098
xref: Reference/ChEBI CHEBI 28494
xref: Reference/BioCyc CARDIOLIPIN
chemical formula: C85H152O17P2
molecular weight: 1507.0505
structure: ChemicalStructure/PW C037552

NADH
type: SmallMolecule
entity reference: NADH

Cardiolipin Biosynthesis CL(18:0/18:1(11Z)/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
type: Pathway
pathway order: PathwayEnzymeReaction/1466012
pathway order: PathwayEnzymeReaction/1466013
pathway order: PathwayEnzymeReaction/1466007
pathway order: PathwayEnzymeReaction/1466008
pathway order: PathwaySubPathway/71931
pathway order: PathwayEnzymeReaction/1466009
pathway order: PathwayEnzymeReaction/1466010
pathway order: PathwayTransport/1466006
pathway order: PathwayEnzymeReaction/1466011
pathway component: ReactionCatalysis113675
pathway component: ReactionCatalysis113676
pathway component: Glycolysis
pathway component: Reaction126566
pathway component: Transport4048
pathway component: Reaction131111
pathway component: Reaction131122
pathway component: ReactionCatalysis113680
pathway component: 2.7.8.5
pathway component: ReactionCatalysis113679
pathway component: Reaction122614
pathway component: ReactionCatalysis112775
pathway component: ReactionCatalysis113677
pathway component: ReactionCatalysis112754
pathway component: 2.7.7.41
pathway component: Reaction131108
xref: Reference/SMPDB SMP0078307
xref: Reference/PathWhiz PW079323
organism: Bos taurus

Reference/ChEBI CHEBI 75354
type: UnificationXref
id: CHEBI:75354
db: ChEBI

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/TAXONOMY 9913
type: UnificationXref
id: 9913
db: TAXONOMY

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Compound/PW C055651/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(18:0/18:1(11Z))
stoichiometric coefficient: 1.0

Compound/PW C055651 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(18:0/18:1(11Z))
stoichiometric coefficient: 1.0

Compound/PW C000064/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

NAD
type: SmallMolecule
entity reference: NAD

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Reference/ChemSpider 388366
type: UnificationXref
id: 388366
db: ChemSpider

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/HMDB HMDB0006521
type: UnificationXref
id: HMDB0006521
db: HMDB

Reference/HMDB HMDB0007854
type: UnificationXref
id: HMDB0007854
db: HMDB

Reference/PubChem-compound 53481823
type: UnificationXref
id: 53481823
db: PubChem-compound

Reference/PubChem-compound 53480610
type: UnificationXref
id: 53480610
db: PubChem-compound

Reference/HMDB HMDB0013505
type: UnificationXref
id: HMDB0013505
db: HMDB

Reference/PathWhiz PW088241
type: UnificationXref
id: PW088241
db: PathWhiz

cis-Vaccenoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 13673-88-6
xref: Reference/ChEBI CHEBI 75354
xref: Reference/HMDB HMDB0006521
xref: Reference/PubChem-compound 53477847
chemical formula: C39H68N7O17P3S
molecular weight: 1031.3605
structure: ChemicalStructure/PW C002789

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/UniProt Q2KJ28
type: UnificationXref
id: Q2KJ28
db: UniProt

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway71931
pathway component: SubPathwayInteraction71931
xref: Reference/SMPDB SMP0087222
xref: Reference/PathWhiz PW088241
name: SubPathway

Compound/PW C003036/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0057098
type: UnificationXref
id: HMDB0057098
db: HMDB

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

PA(18:0/18:1(11Z))
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: PA(18:0/18:1(11Z))

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Compound/PW C002789/Stoichiometry/1.0
type: Stoichiometry
physical entity: cis-Vaccenoyl-CoA
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00344
type: UnificationXref
id: C00344
db: KEGG Compound

Reference/BioCyc CARDIOLIPIN
type: UnificationXref
id: CARDIOLIPIN
db: BioCyc

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Compound/PW C006611/Stoichiometry/1.0
type: Stoichiometry
physical entity: PG(18:0/18:1(11Z))
stoichiometric coefficient: 1.0

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

PGP(18:0/18:1(11Z))
type: SmallMolecule
entity reference: PGP(18:0/18:1(11Z))

ChemicalStructure/PW C003036
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C003030
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

PGP(18:0/18:1(11Z))
type: SmallMoleculeReference
xref: Reference/PubChem-compound 53481823
xref: Reference/ChEBI CHEBI 37393
xref: Reference/HMDB HMDB0013505
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
xref: Reference/KEGG Compound C03892
chemical formula: C42H82O13P2
molecular weight: 856.5231
structure: ChemicalStructure/PW C008421

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reaction131122
type: BiochemicalReaction
participant stoichiometry: Compound/PW C037552/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003036/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006611/Stoichiometry/1.0
right: Cytidine monophosphate
right: CL(18:0/18:1(11Z)/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
spontaneous: false
left: CDP-DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
left: PG(18:0/18:1(11Z))
name: CDP-DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + PG(18:0/18:1(11Z)) → CL(18:0/18:1(11Z)/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + Cytidine monophosphate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis113680
type: Catalysis
controller: CRLS1 protein
controlled: Reaction131122
control type: ACTIVATION

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

PA(18:0/18:1(11Z))
type: SmallMolecule
entity reference: PA(18:0/18:1(11Z))

ChemicalStructure/PW C002789
type: ChemicalStructure
structure format: SMILES

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

PG(18:0/18:1(11Z))
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17517
xref: Reference/HMDB HMDB0010603
xref: Reference/PubChem-compound 53480610
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
xref: Reference/ChemSpider 24768102
xref: Reference/KEGG Compound C00344
chemical formula: C42H81O10P
molecular weight: 776.55676
structure: ChemicalStructure/PW C006611

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Stearoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 362-66-3
xref: Reference/ChEBI CHEBI 15541
xref: Reference/HMDB HMDB0001114
xref: Reference/KEGG Compound C00412
xref: Reference/BioCyc STEAROYL-COA
xref: Reference/ChemSpider 388366
xref: Reference/PubChem-compound 439229
chemical formula: C39H70N7O17P3S
molecular weight: 1033.3762
structure: ChemicalStructure/PW C000871

ReactionCatalysis113675
type: Catalysis
controller: 1-Acyl-sn-glycerol-3-phosphate acyltransferase delta
controlled: Reaction131108
control type: ACTIVATION

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

ReactionCatalysis113676
type: Catalysis
controller: Phosphatidate cytidylyltransferase 2
controlled: 2.7.7.41
control type: ACTIVATION

Reaction126566
type: BiochemicalReaction
participant stoichiometry: Compound/PW C003905/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000871/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
right: Coenzyme A
right: LPA(18:0/0:0)
spontaneous: false
left: Stearoyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Stearoyl-CoA → Coenzyme A + LPA(18:0/0:0)
conversion direction: LEFT_TO_RIGHT

Reaction131111
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006611/Stoichiometry/1.0
participant stoichiometry: Compound/PW C008421/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: PG(18:0/18:1(11Z))
right: Phosphate
spontaneous: false
left: Water
left: PGP(18:0/18:1(11Z))
name: PGP(18:0/18:1(11Z)) + Water → PG(18:0/18:1(11Z)) + Phosphate
conversion direction: LEFT_TO_RIGHT

2.7.8.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C003030/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C008421/Stoichiometry/1.0
right: Cytidine monophosphate
right: PGP(18:0/18:1(11Z))
spontaneous: false
EC number: 2.7.8.5
left: CDP-DG(18:0/18:1(11Z))
left: Glycerol 3-phosphate
name: CDP-DG(18:0/18:1(11Z)) + Glycerol 3-phosphate → Cytidine monophosphate + PGP(18:0/18:1(11Z))
conversion direction: LEFT_TO_RIGHT

Reference/SMPDB SMP0078307
type: UnificationXref
id: SMP0078307
db: SMPDB

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

ReactionCatalysis113679
type: Catalysis
controller: Protein tyrosine phosphatase, mitochondrial 1
controlled: Reaction131111
control type: ACTIVATION

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

LPA(18:0/0:0)
type: SmallMoleculeReference
xref: Reference/PubChem-compound 9547179
xref: Reference/ChemSpider 7826122
xref: Reference/KEGG Compound C00681
xref: Reference/HMDB HMDB0007854
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
xref: Reference/ChEBI CHEBI 74850
chemical formula: C21H43O7P
molecular weight: 438.27463
structure: ChemicalStructure/PW C003905

ReactionCatalysis113677
type: Catalysis
controller: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
controlled: 2.7.8.5
control type: ACTIVATION

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

ChemicalStructure/PW C008421
type: ChemicalStructure
structure format: SMILES

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

LPA(18:0/0:0)
type: SmallMolecule
entity reference: LPA(18:0/0:0)

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

PG(18:0/18:1(11Z))
type: SmallMolecule
entity reference: PG(18:0/18:1(11Z))

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Stearoyl-CoA
type: SmallMolecule
entity reference: Stearoyl-CoA

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Reference/GENE ONTOLOGY GO 0005741
type: UnificationXref
id: GO:0005741
db: GENE ONTOLOGY

2.7.7.41
type: BiochemicalReaction
participant stoichiometry: Compound/PW C003030/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055651/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
right: CDP-DG(18:0/18:1(11Z))
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.41
left: Cytidine triphosphate
left: PA(18:0/18:1(11Z))
name: Cytidine triphosphate + PA(18:0/18:1(11Z)) → CDP-DG(18:0/18:1(11Z)) + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reaction131108
type: BiochemicalReaction
participant stoichiometry: Compound/PW C003905/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055651/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002789/Stoichiometry/1.0
right: Coenzyme A
right: PA(18:0/18:1(11Z))
spontaneous: false
left: LPA(18:0/0:0)
left: cis-Vaccenoyl-CoA
name: LPA(18:0/0:0) + cis-Vaccenoyl-CoA → Coenzyme A + PA(18:0/18:1(11Z))
conversion direction: LEFT_TO_RIGHT

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Compound/PW C000871/Stoichiometry/1.0
type: Stoichiometry
physical entity: Stearoyl-CoA
stoichiometric coefficient: 1.0

CL(18:0/18:1(11Z)/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
type: SmallMolecule
entity reference: CL(18:0/18:1(11Z)/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

Protein tyrosine phosphatase, mitochondrial 1
type: Protein
entity reference: Protein tyrosine phosphatase, mitochondrial 1

Reference/SMPDB SMP0087222
type: UnificationXref
id: SMP0087222
db: SMPDB

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

CRLS1 protein
type: Protein
entity reference: CRLS1 protein

1-Acyl-sn-glycerol-3-phosphate acyltransferase delta
type: Protein
entity reference: 1-Acyl-sn-glycerol-3-phosphate acyltransferase delta

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL
db: BioCyc

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00269
type: UnificationXref
id: C00269
db: KEGG Compound

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
type: Protein
entity reference: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

Reference/KEGG Compound C03892
type: UnificationXref
id: C03892
db: KEGG Compound

PA(18:0/18:1(11Z))
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
chemical formula: C39H75O8P
molecular weight: 702.51996
structure: ChemicalStructure/PW C055651

Cytidine monophosphate
type: SmallMolecule
entity reference: Cytidine monophosphate

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

Reference/ChEBI CHEBI 28494
type: UnificationXref
id: CHEBI:28494
db: ChEBI

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

Reference/ChemSpider 24765819
type: UnificationXref
id: 24765819
db: ChemSpider

Mitochondrial Outer Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005741

Phosphatidate cytidylyltransferase 2
type: Protein
entity reference: Phosphatidate cytidylyltransferase 2

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Dihydroxyacetone phosphate acyltransferase
type: Protein
entity reference: Dihydroxyacetone phosphate acyltransferase

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Reference/UniProt A4IF87
type: UnificationXref
id: A4IF87
db: UniProt

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reaction122614
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: NADH
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH → Glycerol 3-phosphate + NAD
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Reference/UniProt A0JNC1
type: UnificationXref
id: A0JNC1
db: UniProt

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0010603
type: UnificationXref
id: HMDB0010603
db: HMDB

Reference/BioCyc STEAROYL-COA
type: UnificationXref
id: STEAROYL-COA
db: BioCyc

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Compound/PW C008421/Stoichiometry/1.0
type: Stoichiometry
physical entity: PGP(18:0/18:1(11Z))
stoichiometric coefficient: 1.0

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

PA(18:0/18:1(11Z))
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: PA(18:0/18:1(11Z))

Reference/ChEBI CHEBI 17517
type: UnificationXref
id: CHEBI:17517
db: ChEBI

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

CDP-DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
type: SmallMolecule
entity reference: CDP-DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001114
type: UnificationXref
id: HMDB0001114
db: HMDB

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C05980
type: UnificationXref
id: C05980
db: KEGG Compound

Bos taurus
type: BioSource
xref: Reference/TAXONOMY 9913

CDP-DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17962
xref: Reference/ChemSpider 24765825
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/HMDB HMDB0006985
xref: Reference/KEGG Compound C00269
xref: Reference/PubChem-compound 53477929
chemical formula: C52H85N3O15P2
molecular weight: 1053.5455
structure: ChemicalStructure/PW C003036

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Complex
component stoichiometry: Protein/14733/Stoichiometry/2.0
component: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

CDP-DG(18:0/18:1(11Z))
type: SmallMolecule
entity reference: CDP-DG(18:0/18:1(11Z))

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

CDP-DG(18:0/18:1(11Z))
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0006979
xref: Reference/ChEBI CHEBI 17962
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/PubChem-compound 53477923
xref: Reference/KEGG Compound C00269
xref: Reference/ChemSpider 24765819
chemical formula: C48H87N3O15P2
molecular weight: 1007.5612
structure: ChemicalStructure/PW C003030

Reference/ChEBI CHEBI 15541
type: UnificationXref
id: CHEBI:15541
db: ChEBI

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

ChemicalStructure/PW C037552
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 17962
type: UnificationXref
id: CHEBI:17962
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Compound/PW C055651 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(18:0/18:1(11Z))
stoichiometric coefficient: 1.0

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Reference/BioCyc CDPDIACYLGLYCEROL
type: UnificationXref
id: CDPDIACYLGLYCEROL
db: BioCyc

SubPathwayInteraction71931
type: Interaction
name: SubPathway71931Reaction
name: SubPathwayReaction
participant: Dihydroxyacetone phosphate

Reference/PubChem-compound 53477847
type: UnificationXref
id: 53477847
db: PubChem-compound

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/ChEBI CHEBI 37393
type: UnificationXref
id: CHEBI:37393
db: ChEBI

Reference/ChEBI CHEBI 74850
type: UnificationXref
id: CHEBI:74850
db: ChEBI

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/UniProt Q2NKZ7
type: UnificationXref
id: Q2NKZ7
db: UniProt

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

ReactionCatalysis112754
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
controlled: Reaction122614
control type: ACTIVATION

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: ProteinReference
xref: Reference/UniProt Q5EA88

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Compound/PW C037552/Stoichiometry/1.0
type: Stoichiometry
physical entity: CL(18:0/18:1(11Z)/18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

Reference/ChemSpider 24768102
type: UnificationXref
id: 24768102
db: ChemSpider

ChemicalStructure/PW C055651
type: ChemicalStructure
structure format: SMILES

cis-Vaccenoyl-CoA
type: SmallMolecule
entity reference: cis-Vaccenoyl-CoA

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

Phosphatidate cytidylyltransferase 2
type: ProteinReference
xref: Reference/UniProt A0JNC1

Dihydroxyacetone phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt A4IF87

Reference/PubChem-compound 439229
type: UnificationXref
id: 439229
db: PubChem-compound

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/CAS 362-66-3
type: UnificationXref
id: 362-66-3
db: CAS

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q2KJ28

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

Reference/PubChem-compound 53477923
type: UnificationXref
id: 53477923
db: PubChem-compound

Reference/KEGG Compound C00412
type: UnificationXref
id: C00412
db: KEGG Compound

ReactionCatalysis112775
type: Catalysis
controller: Dihydroxyacetone phosphate acyltransferase
controlled: Reaction126566
control type: ACTIVATION

Reference/HMDB HMDB0006979
type: UnificationXref
id: HMDB0006979
db: HMDB

Reference/ChemSpider 7826122
type: UnificationXref
id: 7826122
db: ChemSpider

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C000871
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C006611
type: ChemicalStructure
structure format: SMILES

CRLS1 protein
type: ProteinReference
xref: Reference/UniProt A5PJS7

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Protein tyrosine phosphatase, mitochondrial 1
type: ProteinReference
xref: Reference/UniProt Q2NKZ7

Reference/PubChem-compound 53477929
type: UnificationXref
id: 53477929
db: PubChem-compound

1-Acyl-sn-glycerol-3-phosphate acyltransferase delta
type: ProteinReference
xref: Reference/UniProt Q5E9R2

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 9547179
type: UnificationXref
id: 9547179
db: PubChem-compound

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Compound/PW C003030/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(18:0/18:1(11Z))
stoichiometric coefficient: 1.0

Reference/UniProt Q5EA88
type: UnificationXref
id: Q5EA88
db: UniProt

Reference/CAS 13673-88-6
type: UnificationXref
id: 13673-88-6
db: CAS

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/UniProt A5PJS7
type: UnificationXref
id: A5PJS7
db: UniProt

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C003905
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCCCC(=O)OCC(O)COP(O)(O)=O

Protein/14733/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/PathWhiz PW079323
type: UnificationXref
id: PW079323
db: PathWhiz

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/HMDB HMDB0006985
type: UnificationXref
id: HMDB0006985
db: HMDB

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O