Compound/PW C003905/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(18:0/0:0)
stoichiometric coefficient: 1.0

Reference/ChemSpider 24765820
type: UnificationXref
id: 24765820
db: ChemSpider

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL-P
db: BioCyc

NADH
type: SmallMolecule
entity reference: NADH

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Oleoyl-CoA
type: SmallMolecule
entity reference: Oleoyl-CoA

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C055650 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(18:0/18:1(9Z))
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Compound/PW C000064/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

Reference/UniProt Q19388
type: UnificationXref
id: Q19388
db: UniProt

NAD
type: SmallMolecule
entity reference: NAD

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Reference/ChemSpider 388366
type: UnificationXref
id: 388366
db: ChemSpider

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Reference/PubChem-compound 5280355
type: UnificationXref
id: 5280355
db: PubChem-compound

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Compound/PW C055650/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(18:0/18:1(9Z))
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0084496
type: UnificationXref
id: SMP0084496
db: SMPDB

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/HMDB HMDB0007854
type: UnificationXref
id: HMDB0007854
db: HMDB

Reference/PubChem-compound 53481824
type: UnificationXref
id: 53481824
db: PubChem-compound

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reaction140413
type: BiochemicalReaction
participant stoichiometry: Compound/PW C006612/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C101058/Stoichiometry/1.0
participant stoichiometry: Compound/PW C099573/Stoichiometry/1.0
right: Cytidine monophosphate
right: CL(18:0/18:1(9Z)/18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
spontaneous: false
left: PG(18:0/18:1(9Z))
left: CDP-DG(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
name: CDP-DG(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)) + PG(18:0/18:1(9Z)) → CL(18:0/18:1(9Z)/18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)) + Cytidine monophosphate
conversion direction: LEFT_TO_RIGHT

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

ChemicalStructure/PW C101058
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

CL(18:0/18:1(9Z)/18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
type: SmallMoleculeReference
chemical formula: C83H146O17P2
molecular weight: 1477.0035
structure: ChemicalStructure/PW C101058

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

Reference/PathWhiz PW085514
type: UnificationXref
id: PW085514
db: PathWhiz

Reference/UniProt P53439
type: UnificationXref
id: P53439
db: UniProt

Uncharacterized protein
type: Protein
entity reference: Uncharacterized protein

Probable cardiolipin synthase (CMP-forming)
type: Protein
entity reference: Probable cardiolipin synthase (CMP-forming)

Phosphatidate cytidylyltransferase
type: Protein
entity reference: Phosphatidate cytidylyltransferase

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: Protein
entity reference: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

PA(18:0/18:1(9Z))
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: PA(18:0/18:1(9Z))

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/KEGG Compound C00344
type: UnificationXref
id: C00344
db: KEGG Compound

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

PGP(18:0/18:1(9Z))
type: SmallMoleculeReference
xref: Reference/PubChem-compound 53481824
xref: Reference/ChEBI CHEBI 37393
xref: Reference/HMDB HMDB0013506
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
xref: Reference/KEGG Compound C03892
chemical formula: C42H82O13P2
molecular weight: 856.5231
structure: ChemicalStructure/PW C008422

PGP(18:0/18:1(9Z))
type: SmallMolecule
entity reference: PGP(18:0/18:1(9Z))

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/HMDB HMDB0013506
type: UnificationXref
id: HMDB0013506
db: HMDB

ChemicalStructure/PW C003031
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Compound/PW C003031/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(18:0/18:1(9Z))
stoichiometric coefficient: 1.0

Protein/14779/Stoichiometry/2.0
type: Stoichiometry
physical entity: Probable glycerol-3-phosphate dehydrogenase 2
stoichiometric coefficient: 2.0

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

Probable glycerol-3-phosphate dehydrogenase 2
type: Protein
entity reference: Probable glycerol-3-phosphate dehydrogenase 2

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Reference/UniProt O01916
type: UnificationXref
id: O01916
db: UniProt

Reference/CAS 1716-06-9
type: UnificationXref
id: 1716-06-9
db: CAS

PA(18:0/18:1(9Z))
type: SmallMolecule
entity reference: PA(18:0/18:1(9Z))

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/PathWhiz PW088465
type: UnificationXref
id: PW088465
db: PathWhiz

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Probable glycerol-3-phosphate acyltransferase, mitochondrial
type: Protein
entity reference: Probable glycerol-3-phosphate acyltransferase, mitochondrial

Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
type: Protein
entity reference: Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

PG(18:0/18:1(9Z))
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 73242
xref: Reference/HMDB HMDB0010604
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
xref: Reference/ChemSpider 24768103
xref: Reference/KEGG Compound C00344
xref: Reference/PubChem-compound 24779551
chemical formula: C42H81O10P
molecular weight: 776.55676
structure: ChemicalStructure/PW C006612

Stearoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 362-66-3
xref: Reference/ChEBI CHEBI 15541
xref: Reference/HMDB HMDB0001114
xref: Reference/KEGG Compound C00412
xref: Reference/BioCyc STEAROYL-COA
xref: Reference/ChemSpider 388366
xref: Reference/PubChem-compound 439229
chemical formula: C39H70N7O17P3S
molecular weight: 1033.3762
structure: ChemicalStructure/PW C000871

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/ChEBI CHEBI 15534
type: UnificationXref
id: CHEBI:15534
db: ChEBI

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway77715
pathway component: SubPathwayInteraction77715
xref: Reference/SMPDB SMP0087446
xref: Reference/PathWhiz PW088465
name: SubPathway

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

LPA(18:0/0:0)
type: SmallMoleculeReference
xref: Reference/PubChem-compound 9547179
xref: Reference/ChemSpider 7826122
xref: Reference/KEGG Compound C00681
xref: Reference/HMDB HMDB0007854
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
xref: Reference/ChEBI CHEBI 74850
chemical formula: C21H43O7P
molecular weight: 438.27463
structure: ChemicalStructure/PW C003905

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

CDP-DG(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
type: SmallMolecule
entity reference: CDP-DG(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

Reference/ChEBI CHEBI 73242
type: UnificationXref
id: CHEBI:73242
db: ChEBI

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

CDP-DG(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
type: SmallMoleculeReference
chemical formula: C50H79N3O15P2
molecular weight: 1023.49866
structure: ChemicalStructure/PW C099573

Reference/SMPDB SMP0087446
type: UnificationXref
id: SMP0087446
db: SMPDB

ChemicalStructure/PW C008422
type: ChemicalStructure
structure format: SMILES

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

Compound/PW C099573/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
stoichiometric coefficient: 1.0

Reference/ChemSpider 4444057
type: UnificationXref
id: 4444057
db: ChemSpider

Transport6447
type: Transport
participant stoichiometry: Compound/PW C055650 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055650 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: PA(18:0/18:1(9Z))
spontaneous: false
left: PA(18:0/18:1(9Z))
name: PA(18:0/18:1(9Z)) (→) Transport: Caenorhabditis elegans, Cell, Mitochondrial Outer Membrane to Caenorhabditis elegans, Cell, Mitochondrial Inner Membrane
conversion direction: LEFT_TO_RIGHT

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

LPA(18:0/0:0)
type: SmallMolecule
entity reference: LPA(18:0/0:0)

Reference/UniProt Q93841
type: UnificationXref
id: Q93841
db: UniProt

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

PG(18:0/18:1(9Z))
type: SmallMolecule
entity reference: PG(18:0/18:1(9Z))

Reference/HMDB HMDB0001322
type: UnificationXref
id: HMDB0001322
db: HMDB

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Oleoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001322
xref: Reference/ChemSpider 4444057
xref: Reference/PubChem-compound 5280355
xref: Reference/ChEBI CHEBI 15534
xref: Reference/BioCyc OLEOYL-COA
xref: Reference/CAS 1716-06-9
xref: Reference/KEGG Compound C00510
chemical formula: C39H68N7O17P3S
molecular weight: 1031.3605
structure: ChemicalStructure/PW C001020

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Stearoyl-CoA
type: SmallMolecule
entity reference: Stearoyl-CoA

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Reference/GENE ONTOLOGY GO 0005741
type: UnificationXref
id: GO:0005741
db: GENE ONTOLOGY

SubPathwayInteraction77715
type: Interaction
name: SubPathwayReaction
name: SubPathway77715Reaction
participant: Dihydroxyacetone phosphate

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Compound/PW C000871/Stoichiometry/1.0
type: Stoichiometry
physical entity: Stearoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL
db: BioCyc

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00269
type: UnificationXref
id: C00269
db: KEGG Compound

Reference/KEGG Compound C03892
type: UnificationXref
id: C03892
db: KEGG Compound

ReactionCatalysis128371
type: Catalysis
controller: Uncharacterized protein
controlled: Reaction140369
control type: ACTIVATION

PA(18:0/18:1(9Z))
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
chemical formula: C39H75O8P
molecular weight: 702.51996
structure: ChemicalStructure/PW C055650

ReactionCatalysis128370
type: Catalysis
controller: Phosphatidate cytidylyltransferase
controlled: 2.7.7.41
control type: ACTIVATION

Cytidine monophosphate
type: SmallMolecule
entity reference: Cytidine monophosphate

Compound/PW C006612/Stoichiometry/1.0
type: Stoichiometry
physical entity: PG(18:0/18:1(9Z))
stoichiometric coefficient: 1.0

Reaction140284
type: BiochemicalReaction
participant stoichiometry: Compound/PW C003905/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000871/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
right: Coenzyme A
right: LPA(18:0/0:0)
spontaneous: false
left: Stearoyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Stearoyl-CoA → Coenzyme A + LPA(18:0/0:0)
conversion direction: LEFT_TO_RIGHT

Compound/PW C008422/Stoichiometry/1.0
type: Stoichiometry
physical entity: PGP(18:0/18:1(9Z))
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

Reference/UniProt Q22949
type: UnificationXref
id: Q22949
db: UniProt

Mitochondrial Outer Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005741

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/PubChem-compound 24779551
type: UnificationXref
id: 24779551
db: PubChem-compound

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C001020
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0010604
type: UnificationXref
id: HMDB0010604
db: HMDB

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc STEAROYL-COA
type: UnificationXref
id: STEAROYL-COA
db: BioCyc

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Cardiolipin Biosynthesis CL(18:0/18:1(9Z)/18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
type: Pathway
pathway order: PathwayEnzymeReaction/1604729
pathway order: PathwayEnzymeReaction/1604728
pathway order: PathwayEnzymeReaction/1604727
pathway order: PathwayEnzymeReaction/1604733
pathway order: PathwaySubPathway/77715
pathway order: PathwayEnzymeReaction/1604732
pathway order: PathwayEnzymeReaction/1604731
pathway order: PathwayEnzymeReaction/1604730
pathway order: PathwayTransport/1604724
pathway component: Transport6447
pathway component: Glycolysis
pathway component: Reaction140369
pathway component: ReactionCatalysis128371
pathway component: Reaction140413
pathway component: ReactionCatalysis128370
pathway component: 2.7.7.41
pathway component: 2.7.8.5
pathway component: Reaction140284
pathway component: ReactionCatalysis128202
pathway component: ReactionCatalysis128334
pathway component: ReactionCatalysis128235
pathway component: ReactionCatalysis128234
pathway component: Reaction138125
pathway component: ReactionCatalysis128332
pathway component: Reaction140371
xref: Reference/SMPDB SMP0084496
xref: Reference/PathWhiz PW085514
organism: Caenorhabditis elegans

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Reference/UniProt P34517
type: UnificationXref
id: P34517
db: UniProt

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001114
type: UnificationXref
id: HMDB0001114
db: HMDB

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

CDP-DG(18:0/18:1(9Z))
type: SmallMolecule
entity reference: CDP-DG(18:0/18:1(9Z))

Caenorhabditis elegans
type: BioSource
xref: Reference/TAXONOMY 6239

ReactionCatalysis128235
type: Catalysis
controller: Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
controlled: Reaction140371
control type: ACTIVATION

ReactionCatalysis128234
type: Catalysis
controller: Probable glycerol-3-phosphate acyltransferase, mitochondrial
controlled: Reaction140284
control type: ACTIVATION

Probable glycerol-3-phosphate dehydrogenase 2
type: ProteinReference
xref: Reference/UniProt P34517

CDP-DG(18:0/18:1(9Z))
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17962
xref: Reference/ChemSpider 24765820
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/PubChem-compound 53477924
xref: Reference/KEGG Compound C00269
xref: Reference/HMDB HMDB0006980
chemical formula: C48H87N3O15P2
molecular weight: 1007.5612
structure: ChemicalStructure/PW C003031

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/ChEBI CHEBI 15541
type: UnificationXref
id: CHEBI:15541
db: ChEBI

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Probable cardiolipin synthase (CMP-forming)
type: ProteinReference
xref: Reference/UniProt O01916

Uncharacterized protein
type: ProteinReference
xref: Reference/UniProt Q19388

Reference/TAXONOMY 6239
type: UnificationXref
id: 6239
db: TAXONOMY

Reference/ChEBI CHEBI 17962
type: UnificationXref
id: CHEBI:17962
db: ChEBI

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: ProteinReference
xref: Reference/UniProt Q9BL79

Phosphatidate cytidylyltransferase
type: ProteinReference
xref: Reference/UniProt P53439

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Reference/UniProt Q9BL79
type: UnificationXref
id: Q9BL79
db: UniProt

Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
type: ProteinReference
xref: Reference/UniProt Q93841

Probable glycerol-3-phosphate acyltransferase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q22949

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Complex
component stoichiometry: Protein/14779/Stoichiometry/2.0
component: Probable glycerol-3-phosphate dehydrogenase 2

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

ReactionCatalysis128202
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
controlled: Reaction138125
control type: ACTIVATION

Reference/BioCyc CDPDIACYLGLYCEROL
type: UnificationXref
id: CDPDIACYLGLYCEROL
db: BioCyc

Reaction140371
type: BiochemicalReaction
participant stoichiometry: Compound/PW C003905/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001020/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055650/Stoichiometry/1.0
right: Coenzyme A
right: PA(18:0/18:1(9Z))
spontaneous: false
left: LPA(18:0/0:0)
left: Oleoyl-CoA
name: LPA(18:0/0:0) + Oleoyl-CoA → Coenzyme A + PA(18:0/18:1(9Z))
conversion direction: LEFT_TO_RIGHT

CL(18:0/18:1(9Z)/18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
type: SmallMolecule
entity reference: CL(18:0/18:1(9Z)/18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reaction140369
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006612/Stoichiometry/1.0
participant stoichiometry: Compound/PW C008422/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: PG(18:0/18:1(9Z))
right: Phosphate
spontaneous: false
left: Water
left: PGP(18:0/18:1(9Z))
name: PGP(18:0/18:1(9Z)) + Water → PG(18:0/18:1(9Z)) + Phosphate
conversion direction: LEFT_TO_RIGHT

2.7.7.41
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055650/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003031/Stoichiometry/1.0
right: CDP-DG(18:0/18:1(9Z))
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.41
left: Cytidine triphosphate
left: PA(18:0/18:1(9Z))
name: Cytidine triphosphate + PA(18:0/18:1(9Z)) → CDP-DG(18:0/18:1(9Z)) + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

2.7.8.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C008422/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003031/Stoichiometry/1.0
right: Cytidine monophosphate
right: PGP(18:0/18:1(9Z))
spontaneous: false
EC number: 2.7.8.5
left: CDP-DG(18:0/18:1(9Z))
left: Glycerol 3-phosphate
name: CDP-DG(18:0/18:1(9Z)) + Glycerol 3-phosphate → Cytidine monophosphate + PGP(18:0/18:1(9Z))
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis128334
type: Catalysis
controller: Probable cardiolipin synthase (CMP-forming)
controlled: Reaction140413
control type: ACTIVATION

Reference/BioCyc OLEOYL-COA
type: UnificationXref
id: OLEOYL-COA
db: BioCyc

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

ReactionCatalysis128332
type: Catalysis
controller: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
controlled: 2.7.8.5
control type: ACTIVATION

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/ChEBI CHEBI 37393
type: UnificationXref
id: CHEBI:37393
db: ChEBI

Compound/PW C101058/Stoichiometry/1.0
type: Stoichiometry
physical entity: CL(18:0/18:1(9Z)/18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 74850
type: UnificationXref
id: CHEBI:74850
db: ChEBI

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/KEGG Compound C00510
type: UnificationXref
id: C00510
db: KEGG Compound

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

PA(18:0/18:1(9Z))
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: PA(18:0/18:1(9Z))

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

Reference/ChemSpider 24768103
type: UnificationXref
id: 24768103
db: ChemSpider

ChemicalStructure/PW C055650
type: ChemicalStructure
structure format: SMILES

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Compound/PW C001020/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oleoyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

Reference/PubChem-compound 439229
type: UnificationXref
id: 439229
db: PubChem-compound

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/CAS 362-66-3
type: UnificationXref
id: 362-66-3
db: CAS

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

Reference/KEGG Compound C00412
type: UnificationXref
id: C00412
db: KEGG Compound

ChemicalStructure/PW C006612
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 7826122
type: UnificationXref
id: 7826122
db: ChemSpider

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C000871
type: ChemicalStructure
structure format: SMILES

Compound/PW C055650 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(18:0/18:1(9Z))
stoichiometric coefficient: 1.0

Reference/PubChem-compound 53477924
type: UnificationXref
id: 53477924
db: PubChem-compound

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 9547179
type: UnificationXref
id: 9547179
db: PubChem-compound

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C003905
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCCCC(=O)OCC(O)COP(O)(O)=O

ChemicalStructure/PW C099573
type: ChemicalStructure
structure format: SMILES

Reaction138125
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: NADH
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH → Glycerol 3-phosphate + NAD
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/HMDB HMDB0006980
type: UnificationXref
id: HMDB0006980
db: HMDB

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O