Inositol Phosphate Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/2113397
pathway order: PathwayEnzymeReaction/2113398
pathway order: PathwayEnzymeReaction/2113395
pathway order: PathwayEnzymeReaction/2113396
pathway order: PathwaySubPathway/108370
pathway order: PathwayEnzymeReaction/2113399
pathway order: PathwayEnzymeReaction/2113390
pathway order: PathwayEnzymeReaction/2113393
pathway order: PathwayEnzymeReaction/2113394
pathway order: PathwayEnzymeReaction/2113391
pathway order: PathwayEnzymeReaction/2113392
pathway order: PathwayEnzymeReaction/2113386
pathway order: PathwayEnzymeReaction/2113387
pathway order: PathwayEnzymeReaction/2113384
pathway order: PathwayEnzymeReaction/2113385
pathway order: PathwaySubPathway/108366
pathway order: PathwayEnzymeReaction/2113401
pathway order: PathwayEnzymeReaction/2113402
pathway order: PathwayEnzymeReaction/2113388
pathway order: PathwayEnzymeReaction/2113389
pathway order: PathwayEnzymeReaction/2113400
pathway order: PathwayEnzymeReaction/2113405
pathway order: PathwayEnzymeReaction/2113406
pathway order: PathwayEnzymeReaction/2113403
pathway order: PathwayEnzymeReaction/2113404
pathway order: PathwayEnzymeReaction/2113409
pathway order: PathwaySubPathway/108367
pathway order: PathwaySubPathway/108368
pathway order: PathwayEnzymeReaction/2113407
pathway order: PathwaySubPathway/108369
pathway order: PathwayEnzymeReaction/2113408
pathway order: PathwayEnzymeReaction/2113383
pathway component: ReactionCatalysis136763
pathway component: ReactionCatalysis136764
pathway component: ReactionCatalysis136761
pathway component: ReactionCatalysis136766
pathway component: ReactionCatalysis136767
pathway component: ReactionCatalysis136768
pathway component: ReactionCatalysis136769
pathway component: Pentose Phosphate Pathway
pathway component: 3.1.3.56
pathway component: Reaction146607
pathway component: Reaction146606
pathway component: 3.1.3.66
pathway component: Reaction146603
pathway component: Galactose Metabolism
pathway component: Reaction146602
pathway component: 3.1.3.57
pathway component: ReactionCatalysis136987
pathway component: Reaction146839
pathway component: ReactionCatalysis136988
pathway component: 5.5.1.4
pathway component: ReactionCatalysis136989
pathway component: Reaction146836
pathway component: 2.7.1.151
pathway component: Reaction146830
pathway component: 2.7.1.127
pathway component: Reaction146597
pathway component: 2.7.1.158
pathway component: Reaction146595
pathway component: Starch and Sucrose Metabolism
pathway component: ReactionCatalysis136993
pathway component: ReactionCatalysis136994
pathway component: ReactionCatalysis136995
pathway component: ReactionCatalysis136754
pathway component: ReactionCatalysis136996
pathway component: ReactionCatalysis137000
pathway component: ReactionCatalysis136990
pathway component: ReactionCatalysis136991
pathway component: ReactionCatalysis136992
pathway component: ReactionCatalysis136759
pathway component: 2.7.4.21

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/UniProt F1N1W2
type: UnificationXref
id: F1N1W2
db: UniProt

Reference/CAS 74465-19-3
type: UnificationXref
id: 74465-19-3
db: CAS

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Inositol 1,3,4,5,6-pentakisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16322
xref: Reference/CAS 20298-95-7
xref: Reference/KEGG Compound C01284
xref: Reference/ChemSpider 10333900
xref: Reference/HMDB HMDB0003529
chemical formula: C6H17O21P5
molecular weight: 579.895
structure: ChemicalStructure/PW C001912

Compound/PW C001912 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5,6-pentakisphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 391520
type: UnificationXref
id: 391520
db: ChemSpider

Reference/HMDB HMDB0001187
type: UnificationXref
id: HMDB0001187
db: HMDB

Reference/TAXONOMY 9913
type: UnificationXref
id: 9913
db: TAXONOMY

Inositol 1,3,4,5-tetraphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 107758
xref: Reference/HMDB HMDB0001059
xref: Reference/KEGG Compound C01272
xref: Reference/ChemSpider 96919
xref: Reference/CAS 102850-29-3
xref: Reference/ChEBI CHEBI 16783
xref: Reference/BioCyc CPD-506
chemical formula: C6H16O18P4
molecular weight: 499.9287
structure: ChemicalStructure/PW C000834

Reference/PathWhiz PW000055
type: UnificationXref
id: PW000055
db: PathWhiz

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Adenosine diphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Adenosine diphosphate

Reference/ChemSpider 17216102
type: UnificationXref
id: 17216102
db: ChemSpider

Kinase
type: Protein
cellular location: Nucleus
entity reference: Kinase

1D-Myo-inositol 1,3,4,6-tetrakisphosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 17216082
xref: Reference/CAS 110298-84-5
xref: Reference/BioCyc CPD-505
xref: Reference/HMDB HMDB0001187
xref: Reference/KEGG Compound C04477
xref: Reference/ChEBI CHEBI 16155
chemical formula: C6H16O18P4
molecular weight: 499.9287
structure: ChemicalStructure/PW C000923

Reference/ChemSpider 5743
type: UnificationXref
id: 5743
db: ChemSpider

Reference/BRENDA TISSUE ONTOLOGY BTO 0000759
type: UnificationXref
id: BTO:0000759
db: BRENDA TISSUE ONTOLOGY

Reference/PathWhiz PW000168
type: UnificationXref
id: PW000168
db: PathWhiz

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Compound/PW C000139 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Myo-inositol 1-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16595
type: UnificationXref
id: CHEBI:16595
db: ChEBI

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
type: Protein
cellular location: Cytosol
entity reference: Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

Reference/BioCyc MYO-INOSITOL
type: UnificationXref
id: MYO-INOSITOL
db: BioCyc

Reference/ChemSpider 17216357
type: UnificationXref
id: 17216357
db: ChemSpider

Inositol-tetrakisphosphate 1-kinase
type: Protein
cellular location: Cytosol
entity reference: Inositol-tetrakisphosphate 1-kinase

ChemicalStructure/PW C001083
type: ChemicalStructure
structure format: SMILES

Myo-inositol hexakisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003502
xref: Reference/ChEBI CHEBI 17401
xref: Reference/CAS 83-86-3
xref: Reference/BioCyc MI-HEXAKISPHOSPHATE
xref: Reference/KEGG Compound C01204
xref: Reference/PubChem-compound 890
xref: Reference/ChemSpider 866
chemical formula: C6H18O24P6
molecular weight: 659.8614
structure: ChemicalStructure/PW C001908

Reference/PathWhiz PW000159
type: UnificationXref
id: PW000159
db: PathWhiz

1D-myo-Inositol 3-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-myo-Inositol 3-phosphate

Compound/PW C001034 Nucleus/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 2.0

Compound/PW C001083 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000150
type: UnificationXref
id: PW000150
db: PathWhiz

Compound/PW C001912 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5,6-pentakisphosphate
stoichiometric coefficient: 1.0

Compound/PW C000834 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5-tetraphosphate
stoichiometric coefficient: 1.0

Inositol 1,3,4,5,6-pentakisphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Inositol 1,3,4,5,6-pentakisphosphate

Reference/ChEBI CHEBI 17268
type: UnificationXref
id: CHEBI:17268
db: ChEBI

Reference/ChemSpider 10239179
type: UnificationXref
id: 10239179
db: ChemSpider

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/KEGG Compound C01204
type: UnificationXref
id: C01204
db: KEGG Compound

ChemicalStructure/PW C000923
type: ChemicalStructure
structure format: SMILES

1D-Myo-inositol 1,3,4,6-tetrakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate

Reference/CAS 7664-38-2
type: UnificationXref
id: 7664-38-2
db: CAS

Reference/BioCyc 1-L-MYO-INOSITOL-1-P
type: UnificationXref
id: 1-L-MYO-INOSITOL-1-P
db: BioCyc

Reference/UniProt E1BGX9
type: UnificationXref
id: E1BGX9
db: UniProt

Reference/BioCyc inositol 1,4,5-trisphosphate
type: UnificationXref
id: inositol_1,4,5-trisphosphate
db: BioCyc

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

ChemicalStructure/PW C001908
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

1D-Myo-inositol 1,4,5,6-tetrakisphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Compound/PW C001034 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Compound/PW C002147 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

3.1.3.56
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Inositol 1,3,4-trisphosphate
spontaneous: false
EC number: 3.1.3.56
left: Inositol 1,3,4,5-tetraphosphate
left: Water
name: Inositol 1,3,4,5-tetraphosphate + Water → Inositol 1,3,4-trisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/ChemSpider 388561
type: UnificationXref
id: 388561
db: ChemSpider

Reaction146607
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5-tetraphosphate
spontaneous: false
left: Inositol 1,3,4-trisphosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + Inositol 1,3,4-trisphosphate → Adenosine diphosphate + Inositol 1,3,4,5-tetraphosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChEBI CHEBI 16067
type: UnificationXref
id: CHEBI:16067
db: ChEBI

Reaction146606
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000923 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate
right: Adenosine diphosphate
spontaneous: false
left: Adenosine triphosphate
left: Inositol 1,3,4-trisphosphate
name: Adenosine triphosphate + Inositol 1,3,4-trisphosphate → 1D-Myo-inositol 1,3,4,6-tetrakisphosphate + Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 388562
type: UnificationXref
id: 388562
db: ChemSpider

3.1.3.66
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002679 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002944 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: 1D-myo-Inositol 3-phosphate
spontaneous: false
EC number: 3.1.3.66
left: 1D-Myo-inositol 3,4-bisphosphate
left: Water
name: 1D-Myo-inositol 3,4-bisphosphate + Water → 1D-myo-Inositol 3-phosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Inositol polyphosphate 1-phosphatase
type: Protein
cellular location: Cytosol
entity reference: Inositol polyphosphate 1-phosphatase

Reaction146603
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000137 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002944 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: myo-Inositol
spontaneous: false
left: 1D-myo-Inositol 3-phosphate
left: Water
name: 1D-myo-Inositol 3-phosphate + Water → Phosphate + myo-Inositol
conversion direction: LEFT_TO_RIGHT

Reaction146602
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000137 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000139 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: myo-Inositol
spontaneous: false
left: Myo-inositol 1-phosphate
left: Water
name: Myo-inositol 1-phosphate + Water → Phosphate + myo-Inositol
conversion direction: LEFT_TO_RIGHT

Reference/UniProt Q2NL29
type: UnificationXref
id: Q2NL29
db: UniProt

3.1.3.57
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001441 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001012 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000772 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: D-Myo-inositol 4-phosphate
right: Phosphoric acid
spontaneous: false
EC number: 3.1.3.57
left: 1D-Myo-inositol 1,4-bisphosphate
left: Water
name: 1D-Myo-inositol 1,4-bisphosphate + Water → D-Myo-inositol 4-phosphate + Phosphoric acid
conversion direction: LEFT_TO_RIGHT

Compound/PW C000414 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 2.0

BiologicalState123
type: BioSource
xref: Reference/TAXONOMY 9913
name: Bos taurus, Liver
tissue: Liver

Reference/KEGG Compound C01220
type: UnificationXref
id: C01220
db: KEGG Compound

Inositol polyphosphate-4-phosphatase type I A
type: Protein
cellular location: Cytosol
entity reference: Inositol polyphosphate-4-phosphatase type I A

Reference/KEGG Compound C00137
type: UnificationXref
id: C00137
db: KEGG Compound

Reaction146839
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002147 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001912 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Phosphate
right: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
spontaneous: false
left: Water
left: Inositol 1,3,4,5,6-pentakisphosphate
name: Inositol 1,3,4,5,6-pentakisphosphate + Water → 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

5.5.1.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002944 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001083 Cytosol/Stoichiometry/1.0
right: 1D-myo-Inositol 3-phosphate
spontaneous: false
EC number: 5.5.1.4
left: Glucose 6-phosphate
name: Glucose 6-phosphate → 1D-myo-Inositol 3-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16155
type: UnificationXref
id: CHEBI:16155
db: ChEBI

3.1.3.57
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001441 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002679 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: 1D-Myo-inositol 3,4-bisphosphate
right: Phosphoric acid
spontaneous: false
EC number: 3.1.3.57
left: Inositol 1,3,4-trisphosphate
left: Water
name: Inositol 1,3,4-trisphosphate + Water → 1D-Myo-inositol 3,4-bisphosphate + Phosphoric acid
conversion direction: LEFT_TO_RIGHT

Reaction146836
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001012 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000137 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: myo-Inositol
spontaneous: false
left: D-Myo-inositol 4-phosphate
left: Water
name: D-Myo-inositol 4-phosphate + Water → Phosphate + myo-Inositol
conversion direction: LEFT_TO_RIGHT

3.1.3.56
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000772 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001155 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: 1D-Myo-inositol 1,4-bisphosphate
spontaneous: false
EC number: 3.1.3.56
left: Inositol 1,4,5-trisphosphate
left: Water
name: Inositol 1,4,5-trisphosphate + Water → 1D-Myo-inositol 1,4-bisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C000414 Nucleus/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 2.0

3.1.3.66
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002678 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000892 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: 1D-Myo-inositol 1,3-bisphosphate
spontaneous: false
EC number: 3.1.3.66
left: Inositol 1,3,4-trisphosphate
left: Water
name: Inositol 1,3,4-trisphosphate + Water → 1D-Myo-inositol 1,3-bisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001155 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
right: Inositol 1,3,4,5-tetraphosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.151
left: Inositol 1,4,5-trisphosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + Inositol 1,4,5-trisphosphate → Adenosine diphosphate + Inositol 1,3,4,5-tetraphosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000923 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5,6-pentakisphosphate
spontaneous: false
EC number: 2.7.1.151
left: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate
left: Adenosine triphosphate
name: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate + Adenosine triphosphate → Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5,6-pentakisphosphate
spontaneous: false
EC number: 2.7.1.151
left: Adenosine triphosphate
left: Inositol 1,3,4,5-tetraphosphate
name: Adenosine triphosphate + Inositol 1,3,4,5-tetraphosphate → Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate
conversion direction: LEFT_TO_RIGHT

Reaction146830
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001908 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Inositol 1,3,4,5,6-pentakisphosphate
spontaneous: false
left: Myo-inositol hexakisphosphate
left: Water
name: Myo-inositol hexakisphosphate + Water → Inositol 1,3,4,5,6-pentakisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 83-86-3
type: UnificationXref
id: 83-86-3
db: CAS

Reference/ChEBI CHEBI 18228
type: UnificationXref
id: CHEBI:18228
db: ChEBI

Compound/PW C002678 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,3-bisphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18225
type: UnificationXref
id: CHEBI:18225
db: ChEBI

Reference/BioCyc CPD-3841
type: UnificationXref
id: CPD-3841
db: BioCyc

Compound/PW C001155 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,4,5-trisphosphate
stoichiometric coefficient: 1.0

Synaptojanin-1
type: Protein
cellular location: Cytosol
entity reference: Synaptojanin-1

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

2.7.4.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002676 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001908 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: 5-Diphosphoinositol pentakisphosphate
spontaneous: false
EC number: 2.7.4.21
left: Adenosine triphosphate
left: Myo-inositol hexakisphosphate
name: Adenosine triphosphate + Myo-inositol hexakisphosphate → 5-Diphosphoinositol pentakisphosphate + Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 102850-29-3
type: UnificationXref
id: 102850-29-3
db: CAS

Reaction146828
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002676 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001908 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Myo-inositol hexakisphosphate
spontaneous: false
left: 5-Diphosphoinositol pentakisphosphate
left: Water
name: 5-Diphosphoinositol pentakisphosphate + Water ? Myo-inositol hexakisphosphate + Phosphate

Reaction146827
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002676 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002677 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Bisdiphosphoinositol tetrakisphosphate
spontaneous: false
left: Adenosine triphosphate
left: 5-Diphosphoinositol pentakisphosphate
name: 5-Diphosphoinositol pentakisphosphate + Adenosine triphosphate → Adenosine diphosphate + Bisdiphosphoinositol tetrakisphosphate
conversion direction: LEFT_TO_RIGHT

Reaction146826
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002676 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002677 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: 5-Diphosphoinositol pentakisphosphate
spontaneous: false
left: Bisdiphosphoinositol tetrakisphosphate
left: Water
name: Bisdiphosphoinositol tetrakisphosphate + Water → 5-Diphosphoinositol pentakisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 26078
type: UnificationXref
id: CHEBI:26078
db: ChEBI

Compound/PW C002679 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 3,4-bisphosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0006229
type: UnificationXref
id: HMDB0006229
db: HMDB

Reference/PubChem-compound 440194
type: UnificationXref
id: 440194
db: PubChem-compound

Reference/ChemSpider 26333173
type: UnificationXref
id: 26333173
db: ChemSpider

ReactionCatalysis136763
type: Catalysis
controller: Inositol monophosphatase 1
controlled: Reaction146602
control type: ACTIVATION

Reference/CAS 110298-84-5
type: UnificationXref
id: 110298-84-5
db: CAS

ReactionCatalysis136764
type: Catalysis
controller: Inositol monophosphatase 1
controlled: Reaction146603
control type: ACTIVATION

ReactionCatalysis136761
type: Catalysis
controller: Inositol polyphosphate 1-phosphatase
controlled: 3.1.3.57
control type: ACTIVATION

Reference/KEGG Compound C01243
type: UnificationXref
id: C01243
db: KEGG Compound

Reference/KEGG Compound C03546
type: UnificationXref
id: C03546
db: KEGG Compound

Reference/PubChem-compound 443266
type: UnificationXref
id: 443266
db: PubChem-compound

ReactionCatalysis136766
type: Catalysis
controller: Inositol polyphosphate-4-phosphatase type I A
controlled: 3.1.3.66
control type: ACTIVATION

ReactionCatalysis136767
type: Catalysis
controller: Inositol-tetrakisphosphate 1-kinase
controlled: Reaction146606
control type: ACTIVATION

ReactionCatalysis136768
type: Catalysis
controller: Inositol-tetrakisphosphate 1-kinase
controlled: Reaction146607
control type: ACTIVATION

Reference/ChEBI CHEBI 30164
type: UnificationXref
id: CHEBI:30164
db: ChEBI

ReactionCatalysis136769
type: Catalysis
controller: Synaptojanin-1
controlled: 3.1.3.56
control type: ACTIVATION

Reference/KEGG Compound C01245
type: UnificationXref
id: C01245
db: KEGG Compound

Multiple inositol polyphosphate histidine phosphatase, 1
type: Protein
cellular location: Endoplasmic Reticulum
entity reference: Multiple inositol polyphosphate histidine phosphatase, 1

Compound/PW C000414 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
type: ProteinReference
xref: Reference/UniProt A7Z050
organism: Bos taurus

SubPathwayInteraction108366
type: Interaction
name: SubPathway108366Reaction
name: SubPathwayReaction
participant: Inositol 1,4,5-trisphosphate

SubPathwayInteraction108367
type: Interaction
name: SubPathway108367Reaction
name: SubPathwayReaction
participant: myo-Inositol

SubPathwayInteraction108368
type: Interaction
name: SubPathwayReaction
name: SubPathway108368Reaction
participant: Glucose 6-phosphate

SubPathwayInteraction108369
type: Interaction
name: SubPathway108369Reaction
name: SubPathwayReaction
participant: Glucose 6-phosphate

Reference/ChemSpider 16744067
type: UnificationXref
id: 16744067
db: ChemSpider

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/HMDB HMDB0003529
type: UnificationXref
id: HMDB0003529
db: HMDB

Reference/KEGG Compound C04520
type: UnificationXref
id: C04520
db: KEGG Compound

Reference/ChEBI CHEBI 18169
type: UnificationXref
id: CHEBI:18169
db: ChEBI

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001155
type: ChemicalStructure
structure format: SMILES

1D-Myo-inositol 3,4-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 3,4-bisphosphate

Kinase
type: ProteinReference
xref: Reference/UniProt F1N7H3
organism: Bos taurus

Inositol polyphosphate-4-phosphatase type II B
type: ProteinReference
xref: Reference/UniProt F1MNJ3
organism: Bos taurus

Reference/CAS 46495-39-0
type: UnificationXref
id: 46495-39-0
db: CAS

Kinase
type: Protein
cellular location: Cytosol
entity reference: Kinase

1D-myo-Inositol 3-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0006814
xref: Reference/CAS 2831-74-5
xref: Reference/ChemSpider 389182
xref: Reference/PubChem-compound 440194
xref: Reference/KEGG Compound C04006
xref: Reference/ChEBI CHEBI 18169
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C002944

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

ReactionCatalysis136987
type: Catalysis
controller: Diphosphoinositol polyphosphate phosphohydrolase 1
controlled: Reaction146826
control type: ACTIVATION

ReactionCatalysis136988
type: Catalysis
controller: Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
controlled: Reaction146827
control type: ACTIVATION

Reference/ChEBI CHEBI 4170
type: UnificationXref
id: CHEBI:4170
db: ChEBI

Compound/PW C001420 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ReactionCatalysis136989
type: Catalysis
controller: Diphosphoinositol polyphosphate phosphohydrolase 1
controlled: Reaction146828
control type: ACTIVATION

Reference/HMDB HMDB0006814
type: UnificationXref
id: HMDB0006814
db: HMDB

Water
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Water

D-Myo-inositol 3,4,5,6-tetrakisphosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 108765
xref: Reference/PubChem-compound 121920
xref: Reference/ChEBI CHEBI 15844
xref: Reference/HMDB HMDB0003848
xref: Reference/KEGG Compound C04520
xref: Reference/CAS 112791-61-4
chemical formula: C6H16O18P4
molecular weight: 499.9287
structure: ChemicalStructure/PW C001980

Reference/KEGG Compound C01272
type: UnificationXref
id: C01272
db: KEGG Compound

Compound/PW C001104 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

1D-Myo-inositol 1,4-bisphosphate
type: SmallMoleculeReference
xref: Reference/CAS 74465-19-3
xref: Reference/BioCyc INOSITOL-1,4-BISPHOSPHATE
xref: Reference/ChemSpider 17216032
xref: Reference/KEGG Compound C01220
xref: Reference/HMDB HMDB0000968
xref: Reference/ChEBI CHEBI 17816
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C000772

Inositol 1,3,4-trisphosphate
type: SmallMoleculeReference
xref: Reference/CAS 98102-63-7
xref: Reference/BioCyc INOSITOL-1-3-4-TRIPHOSPHATE
xref: Reference/PubChem-compound 439455
xref: Reference/ChEBI CHEBI 18228
xref: Reference/KEGG Compound C01243
xref: Reference/ChemSpider 388561
xref: Reference/HMDB HMDB0001143
chemical formula: C6H15O15P3
molecular weight: 419.96237
structure: ChemicalStructure/PW C000892

ReactionCatalysis136993
type: Catalysis
controller: Kinase
controlled: 2.7.1.151
control type: ACTIVATION

ReactionCatalysis136994
type: Catalysis
controller: Kinase
controlled: 2.7.1.151
control type: ACTIVATION

ReactionCatalysis136995
type: Catalysis
controller: Inositol polyphosphate-4-phosphatase type II B
controlled: 3.1.3.66
control type: ACTIVATION

ReactionCatalysis136754
type: Catalysis
controller: Kinase
controlled: 2.7.1.151
control type: ACTIVATION

ReactionCatalysis136996
type: Catalysis
controller: Synaptojanin-1
controlled: 3.1.3.56
control type: ACTIVATION

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

ReactionCatalysis136990
type: Catalysis
controller: Kinase
controlled: 2.7.4.21
control type: ACTIVATION

Phosphoric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphoric acid

ReactionCatalysis136991
type: Catalysis
controller: Multiple inositol polyphosphate histidine phosphatase, 1
controlled: Reaction146830
control type: ACTIVATION

ReactionCatalysis136992
type: Catalysis
controller: Kinase
controlled: 2.7.1.151
control type: ACTIVATION

ReactionCatalysis136759
type: Catalysis
controller: Kinase
controlled: 2.7.1.127
control type: ACTIVATION

Reference/ChEBI CHEBI 18384
type: UnificationXref
id: CHEBI:18384
db: ChEBI

Inositol 1,4,5-trisphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Inositol 1,4,5-trisphosphate

ReactionCatalysis136755
type: Catalysis
controller: Kinase
controlled: 2.7.1.151
control type: ACTIVATION

ReactionCatalysis136997
type: Catalysis
controller: Inositol monophosphatase 1
controlled: Reaction146836
control type: ACTIVATION

Reference/PubChem-compound 892
type: UnificationXref
id: 892
db: PubChem-compound

ReactionCatalysis136756
type: Catalysis
controller: Inositol-tetrakisphosphate 1-kinase
controlled: Reaction146595
control type: ACTIVATION

Kinase
type: Protein
cellular location: Cytosol
entity reference: Kinase

ReactionCatalysis136998
type: Catalysis
controller: Inositol polyphosphate 1-phosphatase
controlled: 3.1.3.57
control type: ACTIVATION

Reference/PubChem-compound 890
type: UnificationXref
id: 890
db: PubChem-compound

ReactionCatalysis136757
type: Catalysis
controller: Inositol-pentakisphosphate 2-kinase
controlled: 2.7.1.158
control type: ACTIVATION

ReactionCatalysis136999
type: Catalysis
controller: Inositol-3-phosphate synthase 1
controlled: 5.5.1.4
control type: ACTIVATION

ReactionCatalysis136758
type: Catalysis
controller: Multiple inositol polyphosphate histidine phosphatase, 1
controlled: Reaction146597
control type: ACTIVATION

1D-Myo-inositol 1,4,5,6-tetrakisphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate

Reference/HMDB HMDB0001498
type: UnificationXref
id: HMDB0001498
db: HMDB

ChemicalStructure/PW C001012
type: ChemicalStructure
structure format: SMILES

Compound/PW C002147 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
stoichiometric coefficient: 1.0

SubPathwayInteraction108370
type: Interaction
name: SubPathway108370Reaction
name: SubPathwayReaction
participant: Glucose 6-phosphate

Reference/KEGG Compound C01284
type: UnificationXref
id: C01284
db: KEGG Compound

Reference/HMDB HMDB0004527
type: UnificationXref
id: HMDB0004527
db: HMDB

Compound/PW C000923 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,3,4,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Compound/PW C002944 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-myo-Inositol 3-phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/ChemSpider 979
type: UnificationXref
id: 979
db: ChemSpider

Compound/PW C001980 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Myo-inositol 3,4,5,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Phosphoric acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/ChEBI CHEBI 26078
xref: Reference/CAS 7664-38-2
xref: Reference/PubChem-compound 1004
xref: Reference/ChemSpider 979
xref: Reference/HMDB HMDB0002142
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001441

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0001143
type: UnificationXref
id: HMDB0001143
db: HMDB

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/KEGG Compound C00092
type: UnificationXref
id: C00092
db: KEGG Compound

Compound/PW C001104 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Compound/PW C000772 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,4-bisphosphate
stoichiometric coefficient: 1.0

Myo-inositol hexakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Myo-inositol hexakisphosphate

Reference/CAS 56-73-5
type: UnificationXref
id: 56-73-5
db: CAS

1D-Myo-inositol 1,3-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 1,3-bisphosphate

Multiple inositol polyphosphate histidine phosphatase, 1
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Multiple inositol polyphosphate histidine phosphatase, 1

Compound/PW C001441 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoric acid
stoichiometric coefficient: 1.0

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/UniProt F1N7H3
type: UnificationXref
id: F1N7H3
db: UniProt

Nucleus
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005634

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 866
type: UnificationXref
id: 866
db: ChemSpider

Adenosine triphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Adenosine triphosphate

ChemicalStructure/PW C002147
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001059
type: UnificationXref
id: HMDB0001059
db: HMDB

Inositol-3-phosphate synthase 1
type: Protein
cellular location: Cytosol
entity reference: Inositol-3-phosphate synthase 1

Inositol 1,4,5-trisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Inositol 1,4,5-trisphosphate
name: SubPathwayOutput

Diphosphoinositol polyphosphate phosphohydrolase 1
type: ProteinReference
xref: Reference/UniProt A2VE79
organism: Bos taurus

Reference/HMDB HMDB0002142
type: UnificationXref
id: HMDB0002142
db: HMDB

Compound/PW C002676 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5-Diphosphoinositol pentakisphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 17215924
type: UnificationXref
id: 17215924
db: ChemSpider

Reference/ChEBI CHEBI 15844
type: UnificationXref
id: CHEBI:15844
db: ChEBI

Reference/KEGG Compound C04477
type: UnificationXref
id: C04477
db: KEGG Compound

D-Myo-inositol 4-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Myo-inositol 4-phosphate

Pentose Phosphate Pathway
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108370
pathway component: SubPathwayInteraction108370
xref: Reference/PathWhiz PW000055
xref: Reference/SMPDB SMP0000031
name: SubPathway

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/KEGG Compound C04006
type: UnificationXref
id: C04006
db: KEGG Compound

Reference/PubChem-compound 1004
type: UnificationXref
id: 1004
db: PubChem-compound

Galactose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108368
pathway component: SubPathwayInteraction108368
xref: Reference/PathWhiz PW000159
xref: Reference/SMPDB SMP0000043
name: SubPathway

Compound/PW C002147 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
stoichiometric coefficient: 1.0

Inositol 1,3,4-trisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Inositol 1,3,4-trisphosphate

D-Myo-inositol 4-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001313
xref: Reference/ChEBI CHEBI 18384
xref: Reference/CAS 46495-39-0
xref: Reference/ChemSpider 17216102
xref: Reference/KEGG Compound C03546
xref: Reference/BioCyc D-MYO-INOSITOL-4-PHOSPHATE
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001012

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/BioCyc INOSITOL-1-3-4-TRIPHOSPHATE
type: UnificationXref
id: INOSITOL-1-3-4-TRIPHOSPHATE
db: BioCyc

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/HMDB HMDB0001401
type: UnificationXref
id: HMDB0001401
db: HMDB

Reference/ChemSpider 108765
type: UnificationXref
id: 108765
db: ChemSpider

Compound/PW C001155 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,4,5-trisphosphate
stoichiometric coefficient: 1.0

5-Diphosphoinositol pentakisphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C11526
xref: Reference/HMDB HMDB0006229
xref: Reference/ChemSpider 17216357
xref: Reference/ChEBI CHEBI 30164
chemical formula: C6H19O27P7
molecular weight: 739.8277
structure: ChemicalStructure/PW C002676

Reference/CAS 85166-31-0
type: UnificationXref
id: 85166-31-0
db: CAS

Inositol 1,3,4,5-tetraphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Inositol 1,3,4,5-tetraphosphate

Starch and Sucrose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108369
pathway component: SubPathwayInteraction108369
xref: Reference/SMPDB SMP0000058
xref: Reference/PathWhiz PW000150
name: SubPathway

Myo-inositol 1-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000213
xref: Reference/ChemSpider 17215924
xref: Reference/CAS 2831-74-5
xref: Reference/KEGG Compound C04006
xref: Reference/BioCyc 1-L-MYO-INOSITOL-1-P
xref: Reference/ChEBI CHEBI 18169
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000139

myo-Inositol
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000211
xref: Reference/ChEBI CHEBI 17268
xref: Reference/ChemSpider 10239179
xref: Reference/CAS 87-89-8
xref: Reference/BioCyc MYO-INOSITOL
xref: Reference/KEGG Compound C00137
xref: Reference/PubChem-compound 892
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000137

Bisdiphosphoinositol tetrakisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 52965
xref: Reference/BioCyc CPD-3841
xref: Reference/PubChem-compound 25245165
xref: Reference/HMDB HMDB0006230
xref: Reference/ChemSpider 26333173
chemical formula: C6H20O30P8
molecular weight: 819.794
structure: ChemicalStructure/PW C002677

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

1D-Myo-inositol 1,3-bisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18225
xref: Reference/CAS 103597-56-4
xref: Reference/KEGG Compound C04062
xref: Reference/HMDB HMDB0006234
xref: Reference/BioCyc 5-DIPHOSPHO-1D-MYO-INOSITOL-12346P
xref: Reference/ChemSpider 16744067
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C002678

1D-Myo-inositol 3,4-bisphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440211
xref: Reference/BioCyc PHOSPHATIDYLINOSITOL-345-TRIPHOSPHATE
xref: Reference/KEGG Compound C04063
xref: Reference/ChEBI CHEBI 28858
xref: Reference/HMDB HMDB0006235
xref: Reference/CAS 69256-53-7
xref: Reference/ChemSpider 389196
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C002679

Reference/PubChem-compound 25245165
type: UnificationXref
id: 25245165
db: PubChem-compound

Reference/PubChem-compound 121920
type: UnificationXref
id: 121920
db: PubChem-compound

Reference/ChemSpider 10333900
type: UnificationXref
id: 10333900
db: ChemSpider

Reference/CAS 87-89-8
type: UnificationXref
id: 87-89-8
db: CAS

Reference/UniProt P0C0T1
type: UnificationXref
id: P0C0T1
db: UniProt

Bisdiphosphoinositol tetrakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Bisdiphosphoinositol tetrakisphosphate

Compound/PW C001155 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,4,5-trisphosphate
stoichiometric coefficient: 1.0

myo-Inositol
type: SmallMolecule
cellular location: Cytosol
entity reference: myo-Inositol
name: SubPathwayInput

Reference/HMDB HMDB0000211
type: UnificationXref
id: HMDB0000211
db: HMDB

ChemicalStructure/PW C002676
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000213
type: UnificationXref
id: HMDB0000213
db: HMDB

ChemicalStructure/PW C002677
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Compound/PW C002677 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Bisdiphosphoinositol tetrakisphosphate
stoichiometric coefficient: 1.0

Inositol-pentakisphosphate 2-kinase
type: ProteinReference
xref: Reference/UniProt E1BGX9
organism: Bos taurus

Reference/ChEBI CHEBI 17816
type: UnificationXref
id: CHEBI:17816
db: ChEBI

Reference/SMPDB SMP0000043
type: UnificationXref
id: SMP0000043
db: SMPDB

Multiple inositol polyphosphate histidine phosphatase, 1
type: ProteinReference
xref: Reference/UniProt Q2TBT6
organism: Bos taurus

Reference/CAS 2831-74-5
type: UnificationXref
id: 2831-74-5
db: CAS

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

ChemicalStructure/PW C000139
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0003848
type: UnificationXref
id: HMDB0003848
db: HMDB

ChemicalStructure/PW C000137
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002678
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc D-MYO-INOSITOL-4-PHOSPHATE
type: UnificationXref
id: D-MYO-INOSITOL-4-PHOSPHATE
db: BioCyc

ChemicalStructure/PW C002679
type: ChemicalStructure
structure format: SMILES

Liver
type: TissueVocabulary
xref: Reference/BRENDA TISSUE ONTOLOGY BTO 0000759

Reference/HMDB HMDB0001313
type: UnificationXref
id: HMDB0001313
db: HMDB

1D-Myo-inositol 1,4,5,6-tetrakisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0004527
xref: Reference/CAS 121010-58-0
xref: Reference/ChemSpider 391520
xref: Reference/PubChem-compound 443266
xref: Reference/KEGG Compound C11555
xref: Reference/ChEBI CHEBI 16067
chemical formula: C6H16O18P4
molecular weight: 499.9287
structure: ChemicalStructure/PW C002147

Reference/CAS 121010-58-0
type: UnificationXref
id: 121010-58-0
db: CAS

Kinase
type: ProteinReference
xref: Reference/UniProt A4FV33
organism: Bos taurus

Reference/SMPDB SMP0000058
type: UnificationXref
id: SMP0000058
db: SMPDB

Reference/GENE ONTOLOGY GO 0005634
type: UnificationXref
id: GO:0005634
db: GENE ONTOLOGY

Synaptojanin-1
type: ProteinReference
xref: Reference/UniProt O18964
organism: Bos taurus

Compound/PW C001908 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Myo-inositol hexakisphosphate
stoichiometric coefficient: 1.0

Inositol polyphosphate 1-phosphatase
type: ProteinReference
xref: Reference/UniProt Q1RMJ2
organism: Bos taurus

Reference/BioCyc PHOSPHATIDYLINOSITOL-345-TRIPHOSPHATE
type: UnificationXref
id: PHOSPHATIDYLINOSITOL-345-TRIPHOSPHATE
db: BioCyc

ChemicalStructure/PW C001441
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0003502
type: UnificationXref
id: HMDB0003502
db: HMDB

Reference/PubChem-compound 5958
type: UnificationXref
id: 5958
db: PubChem-compound

Reference/KEGG Compound C04063
type: UnificationXref
id: C04063
db: KEGG Compound

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/KEGG Compound C04062
type: UnificationXref
id: C04062
db: KEGG Compound

Inositol monophosphatase 1
type: ProteinReference
xref: Reference/UniProt Q17QE4
organism: Bos taurus

Reference/CAS 98102-63-7
type: UnificationXref
id: 98102-63-7
db: CAS

Reference/ChemSpider 389196
type: UnificationXref
id: 389196
db: ChemSpider

Compound/PW C000834 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5-tetraphosphate
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Inositol 1,4,5-trisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001498
xref: Reference/PubChem-compound 439456
xref: Reference/CAS 85166-31-0
xref: Reference/BioCyc inositol 1,4,5-trisphosphate
xref: Reference/KEGG Compound C01245
xref: Reference/ChEBI CHEBI 16595
xref: Reference/ChemSpider 388562
chemical formula: C6H15O15P3
molecular weight: 419.96237
structure: ChemicalStructure/PW C001155

Inositol 1,4,5-trisphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Inositol 1,4,5-trisphosphate

Compound/PW C000834 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4,5-tetraphosphate
stoichiometric coefficient: 1.0

Inositol polyphosphate-4-phosphatase type I A
type: ProteinReference
xref: Reference/UniProt E1B820
organism: Bos taurus

Multiple inositol polyphosphate histidine phosphatase, 1
type: Protein
cellular location: Cytosol
entity reference: Multiple inositol polyphosphate histidine phosphatase, 1

Endoplasmic Reticulum
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005783

Inositol 1,3,4,5-tetraphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Inositol 1,3,4,5-tetraphosphate

Endoplasmic Reticulum Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005789

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

D-Myo-inositol 3,4,5,6-tetrakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Myo-inositol 3,4,5,6-tetrakisphosphate

Reference/UniProt F1MNJ3
type: UnificationXref
id: F1MNJ3
db: UniProt

Reference/HMDB HMDB0006234
type: UnificationXref
id: HMDB0006234
db: HMDB

Reference/HMDB HMDB0006235
type: UnificationXref
id: HMDB0006235
db: HMDB

Reference/HMDB HMDB0006230
type: UnificationXref
id: HMDB0006230
db: HMDB

Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00092
xref: Reference/BioCyc GLC-6-P
xref: Reference/HMDB HMDB0001401
xref: Reference/PubChem-compound 5958
xref: Reference/ChemSpider 5743
xref: Reference/CAS 56-73-5
xref: Reference/ChEBI CHEBI 4170
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001083

Reference/UniProt Q1RMJ2
type: UnificationXref
id: Q1RMJ2
db: UniProt

Reference/UniProt A2VE79
type: UnificationXref
id: A2VE79
db: UniProt

Reference/ChEBI CHEBI 16783
type: UnificationXref
id: CHEBI:16783
db: ChEBI

Bos taurus
type: BioSource
xref: Reference/TAXONOMY 9913

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Water
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Water

Reference/CAS 103597-56-4
type: UnificationXref
id: 103597-56-4
db: CAS

Reference/ChemSpider 389182
type: UnificationXref
id: 389182
db: ChemSpider

Myo-inositol 1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Myo-inositol 1-phosphate

Reference/ChemSpider 96919
type: UnificationXref
id: 96919
db: ChemSpider

Inositol monophosphatase 1
type: Protein
cellular location: Cytosol
entity reference: Inositol monophosphatase 1

Inositol-3-phosphate synthase 1
type: ProteinReference
xref: Reference/UniProt Q2NL29
organism: Bos taurus

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/SMPDB SMP0087256
type: UnificationXref
id: SMP0087256
db: SMPDB

Phosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Phosphate

5-Diphosphoinositol pentakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 5-Diphosphoinositol pentakisphosphate

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001912
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 439455
type: UnificationXref
id: 439455
db: PubChem-compound

Reference/PubChem-compound 439456
type: UnificationXref
id: 439456
db: PubChem-compound

Diphosphoinositol polyphosphate phosphohydrolase 1
type: Protein
cellular location: Cytosol
entity reference: Diphosphoinositol polyphosphate phosphohydrolase 1

Reference/GENE ONTOLOGY GO 0005789
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

2.7.1.127
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001155 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000834 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5-tetraphosphate
spontaneous: false
EC number: 2.7.1.127
left: Adenosine triphosphate
left: Inositol 1,4,5-trisphosphate
name: Adenosine triphosphate + Inositol 1,4,5-trisphosphate → Adenosine diphosphate + Inositol 1,3,4,5-tetraphosphate
conversion direction: LEFT_TO_RIGHT

Reaction146597
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000834 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001155 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Endoplasmic Reticulum/Stoichiometry/1.0
right: Inositol 1,4,5-trisphosphate
right: Phosphate
spontaneous: false
left: Water
left: Inositol 1,3,4,5-tetraphosphate
name: Inositol 1,3,4,5-tetraphosphate + Water → Inositol 1,4,5-trisphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.158
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001908 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Myo-inositol hexakisphosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.158
left: Adenosine triphosphate
left: Inositol 1,3,4,5,6-pentakisphosphate
name: Adenosine triphosphate + Inositol 1,3,4,5,6-pentakisphosphate → Adenosine diphosphate + Myo-inositol hexakisphosphate
conversion direction: LEFT_TO_RIGHT

Reaction146595
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001980 Cytosol/Stoichiometry/1.0
right: Adenosine triphosphate
right: D-Myo-inositol 3,4,5,6-tetrakisphosphate
spontaneous: false
left: Adenosine diphosphate
left: Inositol 1,3,4,5,6-pentakisphosphate
name: Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate → Adenosine triphosphate + D-Myo-inositol 3,4,5,6-tetrakisphosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/2.0
participant stoichiometry: Compound/PW C002147 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001912 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/2.0
right: Adenosine diphosphate
right: Inositol 1,3,4,5,6-pentakisphosphate
spontaneous: false
EC number: 2.7.1.151
left: Adenosine triphosphate
left: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
name: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + 2 Adenosine triphosphate → 2 Adenosine diphosphate + Inositol 1,3,4,5,6-pentakisphosphate
conversion direction: LEFT_TO_RIGHT

Reference/GENE ONTOLOGY GO 0005783
type: UnificationXref
id: GO:0005783
db: GENE ONTOLOGY

2.7.1.151
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001155 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/2.0
participant stoichiometry: Compound/PW C002147 Nucleus/Stoichiometry/1.0
right: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.151
left: Inositol 1,4,5-trisphosphate
left: Adenosine triphosphate
name: 2 Adenosine triphosphate + Inositol 1,4,5-trisphosphate → 1D-Myo-inositol 1,4,5,6-tetrakisphosphate + 2 Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/PubChem-compound 107758
type: UnificationXref
id: 107758
db: PubChem-compound

Compound/PW C000137 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: myo-Inositol
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Inositol-pentakisphosphate 2-kinase
type: Protein
cellular location: Cytosol
entity reference: Inositol-pentakisphosphate 2-kinase

ChemicalStructure/PW C000834
type: ChemicalStructure
structure format: SMILES

Reference/UniProt A7Z050
type: UnificationXref
id: A7Z050
db: UniProt

Reference/ChemSpider 17216082
type: UnificationXref
id: 17216082
db: ChemSpider

Reference/BioCyc GLC-6-P
type: UnificationXref
id: GLC-6-P
db: BioCyc

Phosphatidylinositol Phosphate Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108366
pathway order: SubPathwayInteractionSteps/SubPathway108367
pathway component: SubPathwayInteraction108366
pathway component: SubPathwayInteraction108367
xref: Reference/PathWhiz PW000168
xref: Reference/SMPDB SMP0000463
name: SubPathway

Compound/PW C001034 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 28858
type: UnificationXref
id: CHEBI:28858
db: ChEBI

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Kinase
type: ProteinReference
xref: Reference/UniProt F1N1W2
organism: Bos taurus

Inositol-tetrakisphosphate 1-kinase
type: ProteinReference
xref: Reference/UniProt P0C0T1
organism: Bos taurus

Reference/SMPDB SMP0000031
type: UnificationXref
id: SMP0000031
db: SMPDB

Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glucose 6-phosphate
name: SubPathwayOutput

Reference/HMDB HMDB0000968
type: UnificationXref
id: HMDB0000968
db: HMDB

ChemicalStructure/PW C002944
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001980
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C11526
type: UnificationXref
id: C11526
db: KEGG Compound

ChemicalStructure/PW C000772
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000892
type: ChemicalStructure
structure format: SMILES

Reference/UniProt E1B820
type: UnificationXref
id: E1B820
db: UniProt

Reference/UniProt Q17QE4
type: UnificationXref
id: Q17QE4
db: UniProt

Reference/BioCyc 5-DIPHOSPHO-1D-MYO-INOSITOL-12346P
type: UnificationXref
id: 5-DIPHOSPHO-1D-MYO-INOSITOL-12346P
db: BioCyc

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/UniProt A4FV33
type: UnificationXref
id: A4FV33
db: UniProt

Inositol polyphosphate-4-phosphatase type II B
type: Protein
cellular location: Cytosol
entity reference: Inositol polyphosphate-4-phosphatase type II B

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

1D-Myo-inositol 1,4,5,6-tetrakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 1,4,5,6-tetrakisphosphate

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Reference/CAS 20298-95-7
type: UnificationXref
id: 20298-95-7
db: CAS

Reference/PubChem-compound 440211
type: UnificationXref
id: 440211
db: PubChem-compound

Inositol 1,3,4,5,6-pentakisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Inositol 1,3,4,5,6-pentakisphosphate

Reference/BioCyc CPD-505
type: UnificationXref
id: CPD-505
db: BioCyc

Inositol 1,3,4,5-tetraphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Inositol 1,3,4,5-tetraphosphate

Phosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Phosphate

Reference/BioCyc CPD-506
type: UnificationXref
id: CPD-506
db: BioCyc

Reference/ChEBI CHEBI 17401
type: UnificationXref
id: CHEBI:17401
db: ChEBI

1D-Myo-inositol 1,4-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1D-Myo-inositol 1,4-bisphosphate

Reference/BioCyc MI-HEXAKISPHOSPHATE
type: UnificationXref
id: MI-HEXAKISPHOSPHATE
db: BioCyc

Compound/PW C001420 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Compound/PW C001012 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Myo-inositol 4-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 52965
type: UnificationXref
id: CHEBI:52965
db: ChEBI

Reference/ChemSpider 17216032
type: UnificationXref
id: 17216032
db: ChemSpider

Reference/CAS 69256-53-7
type: UnificationXref
id: 69256-53-7
db: CAS

Reference/SMPDB SMP0000463
type: UnificationXref
id: SMP0000463
db: SMPDB

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/ChEBI CHEBI 16322
type: UnificationXref
id: CHEBI:16322
db: ChEBI

ReactionCatalysis137000
type: Catalysis
controller: Multiple inositol polyphosphate histidine phosphatase, 1
controlled: Reaction146839
control type: ACTIVATION

Compound/PW C000892 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inositol 1,3,4-trisphosphate
stoichiometric coefficient: 1.0

Reference/PathWhiz PW088275
type: UnificationXref
id: PW088275
db: PathWhiz

Reference/UniProt O18964
type: UnificationXref
id: O18964
db: UniProt

Reference/UniProt Q2TBT6
type: UnificationXref
id: Q2TBT6
db: UniProt

Reference/BioCyc INOSITOL-1,4-BISPHOSPHATE
type: UnificationXref
id: INOSITOL-1,4-BISPHOSPHATE
db: BioCyc

Kinase
type: Protein
cellular location: Cytosol
entity reference: Kinase

Reference/KEGG Compound C11555
type: UnificationXref
id: C11555
db: KEGG Compound

Reference/CAS 112791-61-4
type: UnificationXref
id: 112791-61-4
db: CAS