Reference/UniProt Q29RZ0
type: UnificationXref
id: Q29RZ0
db: UniProt

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/CAS 142-62-1
type: UnificationXref
id: 142-62-1
db: CAS

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Adenosine triphosphate
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Adenosine triphosphate

Reference/ChemSpider 8552
type: UnificationXref
id: 8552
db: ChemSpider

Reference/ChemSpider 388353
type: UnificationXref
id: 388353
db: ChemSpider

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Reference/HMDB HMDB0000535
type: UnificationXref
id: HMDB0000535
db: HMDB

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Reference/TAXONOMY 9913
type: UnificationXref
id: 9913
db: TAXONOMY

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

Hexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Hexanoyl-CoA

Reference/ChEBI CHEBI 57371
type: UnificationXref
id: CHEBI:57371
db: ChEBI

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

ReactionCatalysis137108
type: Catalysis
controller: Acyl-CoA synthetase short-chain family member 3, mitochondrial
controlled: 6.2.1.1
control type: ACTIVATION

Protein/15184 Mitochondrion/Stoichiometry/4.0
type: Stoichiometry
physical entity: Short-chain specific acyl-CoA dehydrogenase, mitochondrial
stoichiometric coefficient: 4.0

Reference/PathWhiz PW000172
type: UnificationXref
id: PW000172
db: PathWhiz

Compound/PW C002007 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxohexanoyl-CoA
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/HMDB HMDB0002845
type: UnificationXref
id: HMDB0002845
db: HMDB

Reference/CAS 5060-32-2
type: UnificationXref
id: 5060-32-2
db: CAS

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/CAS 102680-35-3
type: UnificationXref
id: 102680-35-3
db: CAS

Compound/PW C002006 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxyhexanoyl-CoA
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000167
type: UnificationXref
id: PW000167
db: PathWhiz

Compound/PW C000856 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Butyryl-CoA
stoichiometric coefficient: 1.0

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
type: Complex
component stoichiometry: Protein/15401 Mitochondrial Matrix/Stoichiometry/2.0
cellular location: Mitochondrial Matrix
component: Hydroxyacyl-CoA dehydrogenase

Hexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Hexanoyl-CoA
name: SubPathwayOutput

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 5280381
type: UnificationXref
id: 5280381
db: PubChem-compound

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/PubChem-compound 265
type: UnificationXref
id: 265
db: PubChem-compound

Caproic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Caproic acid
name: SubPathwayOutput

Reference/KEGG Compound C00332
type: UnificationXref
id: C00332
db: KEGG Compound

Reference/ChEBI CHEBI 30776
type: UnificationXref
id: CHEBI:30776
db: ChEBI

Reference/HMDB HMDB0003942
type: UnificationXref
id: HMDB0003942
db: HMDB

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Fatty Acid Elongation in Mitochondria
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108388
pathway component: SubPathwayInteraction108388
xref: Reference/PathWhiz PW000022
xref: Reference/SMPDB SMP0000054
name: SubPathway

ReactionCatalysis135927
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

Reference/PubChem-compound 440045
type: UnificationXref
id: 440045
db: PubChem-compound

3-ketoacyl-CoA thiolase, mitochondrial
type: Complex
component stoichiometry: Protein/15159 Mitochondrial Matrix/Stoichiometry/4.0
cellular location: Mitochondrial Matrix
component: 3-ketoacyl-CoA thiolase, mitochondrial

Reference/HMDB HMDB0003943
type: UnificationXref
id: HMDB0003943
db: HMDB

Reference/HMDB HMDB0003944
type: UnificationXref
id: HMDB0003944
db: HMDB

Crotonoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00877
xref: Reference/HMDB HMDB0002009
xref: Reference/PubChem-compound 5280381
xref: Reference/CAS 102680-35-3
xref: Reference/BioCyc CPD-1083
xref: Reference/ChEBI CHEBI 15473
xref: Reference/ChemSpider 4444072
chemical formula: C25H40N7O17P3S
molecular weight: 835.1414
structure: ChemicalStructure/PW C001345

Reduced electron-transfer flavoprotein
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Reduced electron-transfer flavoprotein

Butyryl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Butyryl-CoA

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/HMDB HMDB0001088
type: UnificationXref
id: HMDB0001088
db: HMDB

Citric Acid Cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108386
pathway component: SubPathwayInteraction108386
xref: Reference/PathWhiz PW000005
xref: Reference/SMPDB SMP0000057
name: SubPathway

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

Reference/BioCyc K-HEXANOYL-COA
type: UnificationXref
id: K-HEXANOYL-COA
db: BioCyc

Reference/UniProt Q2TBG6
type: UnificationXref
id: Q2TBG6
db: UniProt

3-hydroxyacyl-CoA dehydrogenase type-2
type: Protein
cellular location: Mitochondrial Matrix
entity reference: 3-hydroxyacyl-CoA dehydrogenase type-2

Reference/UniProt B4X9P2
type: UnificationXref
id: B4X9P2
db: UniProt

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Compound/PW C002008 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Hexenoyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/ChemSpider 260
type: UnificationXref
id: 260
db: ChemSpider

Mitochondrion
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005739

Caproic acid
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Caproic acid

Hexanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0002845
xref: Reference/KEGG Compound C05270
xref: Reference/ChemSpider 395736
xref: Reference/CAS 5060-32-2
xref: Reference/PubChem-compound 449118
xref: Reference/ChEBI CHEBI 27540
chemical formula: C27H46N7O17P3S
molecular weight: 865.18835
structure: ChemicalStructure/PW C001719

electron-transfer flavoprotein
type: SmallMolecule
cellular location: Mitochondrion
entity reference: electron-transfer flavoprotein

3-Hydroxyhexanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003942
xref: Reference/CAS 79171-47-4
xref: Reference/KEGG Compound C05268
xref: Reference/PubChem-compound 11966160
xref: Reference/ChEBI CHEBI 28276
xref: Reference/ChemSpider 10140154
chemical formula: C27H46N7O18P3S
molecular weight: 881.1833
structure: ChemicalStructure/PW C002006

ReactionCatalysis135911
type: Catalysis
controller: Short-chain specific acyl-CoA dehydrogenase, mitochondrial
controlled: 1.3.8.1
control type: ACTIVATION

3-Oxohexanoyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc K-HEXANOYL-COA
xref: Reference/HMDB HMDB0003943
xref: Reference/ChEBI CHEBI 27648
xref: Reference/ChemSpider 389508
xref: Reference/CAS 19774-86-8
xref: Reference/KEGG Compound C05269
xref: Reference/PubChem-compound 440610
chemical formula: C27H44N7O18P3S
molecular weight: 879.16766
structure: ChemicalStructure/PW C002007

(2E)-Hexenoyl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5280765
xref: Reference/KEGG Compound C05271
xref: Reference/ChemSpider 4444331
xref: Reference/HMDB HMDB0003944
xref: Reference/ChEBI CHEBI 28706
xref: Reference/CAS 10018-93-6
chemical formula: C27H44N7O17P3S
molecular weight: 863.1727
structure: ChemicalStructure/PW C002008

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

ReactionCatalysis135914
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

Reference/ChEBI CHEBI 5086
type: UnificationXref
id: CHEBI:5086
db: ChEBI

Short-chain specific acyl-CoA dehydrogenase, mitochondrial
type: Complex
component stoichiometry: Protein/15184 Mitochondrion/Stoichiometry/4.0
cellular location: Mitochondrion
component: Short-chain specific acyl-CoA dehydrogenase, mitochondrial

Reference/ChemSpider 4444072
type: UnificationXref
id: 4444072
db: ChemSpider

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Adenosine monophosphate
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Adenosine monophosphate

Compound/Generic70 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Reduced electron-transfer flavoprotein
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001345
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 10140154
type: UnificationXref
id: 10140154
db: ChemSpider

Compound/PW C000412 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Caproic acid
stoichiometric coefficient: 1.0

3-Oxohexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Oxohexanoyl-CoA

3-hydroxyacyl-CoA dehydrogenase type-2
type: ProteinReference
xref: Reference/UniProt Q2TBG6
organism: Bos taurus

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

ReactionCatalysis135922
type: Catalysis
controller: Acetyl-CoA acetyltransferase, mitochondrial
controlled: 2.3.1.9
control type: ACTIVATION

Reference/ChEBI CHEBI 28706
type: UnificationXref
id: CHEBI:28706
db: ChEBI

ReactionCatalysis135921
type: Catalysis
controller: 3-ketoacyl-CoA thiolase, mitochondrial
controlled: 2.3.1.9
control type: ACTIVATION

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

NADH
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: NADH

ReactionCatalysis135926
type: Catalysis
controller: Long-chain specific acyl-CoA dehydrogenase, mitochondrial
controlled: 1.3.8.8
control type: ACTIVATION

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/BioCyc CPD-1083
type: UnificationXref
id: CPD-1083
db: BioCyc

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/PubChem-compound 440610
type: UnificationXref
id: 440610
db: PubChem-compound

ReactionCatalysis135918
type: Catalysis
controller: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
controlled: Reaction145818
control type: ACTIVATION

ReactionCatalysis135916
type: Catalysis
controller: 3-hydroxyacyl-CoA dehydrogenase type-2
controlled: Reaction145818
control type: ACTIVATION

Compound/PW C000940 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 2.0

Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108389
pathway component: SubPathwayInteraction108389
xref: Reference/SMPDB SMP0000481
xref: Reference/PathWhiz PW000172
name: SubPathway

Reference/GENE ONTOLOGY GO 0005759
type: UnificationXref
id: GO:0005759
db: GENE ONTOLOGY

Pyrophosphate
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Pyrophosphate

Coenzyme A
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Coenzyme A

Protein/15540 Mitochondrial Matrix/Stoichiometry/4.0
type: Stoichiometry
physical entity: 3-hydroxyacyl-CoA dehydrogenase type-2
stoichiometric coefficient: 4.0

Reference/SMPDB SMP0000057
type: UnificationXref
id: SMP0000057
db: SMPDB

Reference/CAS 19774-86-8
type: UnificationXref
id: 19774-86-8
db: CAS

Reference/SMPDB SMP0000054
type: UnificationXref
id: SMP0000054
db: SMPDB

Reference/ChEBI CHEBI 28276
type: UnificationXref
id: CHEBI:28276
db: ChEBI

ChemicalStructure/PW C000904
type: ChemicalStructure
structure format: SMILES

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/KEGG Compound C01585
type: UnificationXref
id: C01585
db: KEGG Compound

Enoyl-CoA hydratase, mitochondrial
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Enoyl-CoA hydratase, mitochondrial

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/KEGG Compound C05268
type: UnificationXref
id: C05268
db: KEGG Compound

Reference/PubChem-compound 11966160
type: UnificationXref
id: 11966160
db: PubChem-compound

Reference/KEGG Compound C00136
type: UnificationXref
id: C00136
db: KEGG Compound

(2E)-Hexenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Hexenoyl-CoA

Isovaleryl-CoA dehydrogenase, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Isovaleryl-CoA dehydrogenase, mitochondrial

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/KEGG Compound C05269
type: UnificationXref
id: C05269
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Hydrogen Ion

Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Acetoacetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETOACETYL-COA
xref: Reference/PubChem-compound 439214
xref: Reference/ChEBI CHEBI 15345
xref: Reference/CAS 1420-36-6
xref: Reference/HMDB HMDB0001484
xref: Reference/KEGG Compound C00332
xref: Reference/ChemSpider 388353
chemical formula: C25H40N7O18P3S
molecular weight: 851.13635
structure: ChemicalStructure/PW C001142

Reference/KEGG Compound C05271
type: UnificationXref
id: C05271
db: KEGG Compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/KEGG Compound C05270
type: UnificationXref
id: C05270
db: KEGG Compound

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/ChemSpider 389508
type: UnificationXref
id: 389508
db: ChemSpider

2.3.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000940 Mitochondrial Matrix/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001142 Mitochondrial Matrix/Stoichiometry/1.0
right: Acetyl-CoA
spontaneous: false
EC number: 2.3.1.9
left: Coenzyme A
left: Acetoacetyl-CoA
name: Acetoacetyl-CoA + Coenzyme A → 2 Acetyl-CoA
conversion direction: LEFT_TO_RIGHT

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Butyryl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 2140-48-9
xref: Reference/ChEBI CHEBI 57371
xref: Reference/ChemSpider 260
xref: Reference/PubChem-compound 265
xref: Reference/KEGG Compound C00136
xref: Reference/BioCyc CPD-12174
xref: Reference/HMDB HMDB0001088
chemical formula: C25H42N7O17P3S
molecular weight: 837.15704
structure: ChemicalStructure/PW C000856

Reference/PubChem-compound 8892
type: UnificationXref
id: 8892
db: PubChem-compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Compound/PW C001719 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hexanoyl-CoA
stoichiometric coefficient: 1.0

6.2.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000032 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000412 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001719 Mitochondrial Matrix/Stoichiometry/1.0
right: Adenosine monophosphate
right: Hexanoyl-CoA
right: Pyrophosphate
spontaneous: false
EC number: 6.2.1.1
left: Coenzyme A
left: Adenosine triphosphate
left: Caproic acid
name: Adenosine triphosphate + Caproic acid + Coenzyme A → Adenosine monophosphate + Hexanoyl-CoA + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/GENE ONTOLOGY GO 0005739
type: UnificationXref
id: GO:0005739
db: GENE ONTOLOGY

Compound/PW C000940 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Acyl-CoA synthetase short-chain family member 3, mitochondrial
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Acyl-CoA synthetase short-chain family member 3, mitochondrial

Acetyl-CoA acetyltransferase, mitochondrial
type: Complex
component stoichiometry: Protein/15185 Mitochondrial Matrix/Stoichiometry/4.0
cellular location: Mitochondrial Matrix
component: Acetyl-CoA acetyltransferase, mitochondrial

Compound/PW C000170 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/CAS 79171-47-4
type: UnificationXref
id: 79171-47-4
db: CAS

ReactionCatalysis136408
type: Catalysis
controller: Acetyl-CoA acetyltransferase, mitochondrial
controlled: 2.3.1.9
control type: ACTIVATION

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis136409
type: Catalysis
controller: 3-ketoacyl-CoA thiolase, mitochondrial
controlled: 2.3.1.9
control type: ACTIVATION

electron-transfer flavoprotein
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 5086

Isovaleryl-CoA dehydrogenase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q3SZI8
organism: Bos taurus

Compound/PW C000414 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/BioCyc 2-METHYL-3-HYDROXY-BUTYRYL-COA
type: UnificationXref
id: 2-METHYL-3-HYDROXY-BUTYRYL-COA
db: BioCyc

Reference/PubChem-compound 5280765
type: UnificationXref
id: 5280765
db: PubChem-compound

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reduced electron-transfer flavoprotein
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 5086

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Reference/CAS 2871-66-1
type: UnificationXref
id: 2871-66-1
db: CAS

ChemicalStructure/PW C001142
type: ChemicalStructure
structure format: SMILES

Protein/15185 Mitochondrial Matrix/Stoichiometry/4.0
type: Stoichiometry
physical entity: Acetyl-CoA acetyltransferase, mitochondrial
stoichiometric coefficient: 4.0

Mitochondrial Matrix
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005759

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/SMPDB SMP0000481
type: UnificationXref
id: SMP0000481
db: SMPDB

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/ChemSpider 395736
type: UnificationXref
id: 395736
db: ChemSpider

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Acetyl-CoA acetyltransferase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q29RZ0
organism: Bos taurus

Short-chain specific acyl-CoA dehydrogenase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q3ZBF6
organism: Bos taurus

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Reference/BioCyc CPD-12174
type: UnificationXref
id: CPD-12174
db: BioCyc

Reference/ChEBI CHEBI 15452
type: UnificationXref
id: CHEBI:15452
db: ChEBI

Compound/PW C001142 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetoacetyl-CoA
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000856
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 389056
type: UnificationXref
id: 389056
db: ChemSpider

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

ChemicalStructure/PW C002006
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C03561
type: UnificationXref
id: C03561
db: KEGG Compound

Protein/15159 Mitochondrial Matrix/Stoichiometry/4.0
type: Stoichiometry
physical entity: 3-ketoacyl-CoA thiolase, mitochondrial
stoichiometric coefficient: 4.0

Bos taurus
type: BioSource
xref: Reference/TAXONOMY 9913

3-Hydroxybutyryl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Hydroxybutyryl-CoA

Reference/ChEBI CHEBI 27540
type: UnificationXref
id: CHEBI:27540
db: ChEBI

Reference/BioCyc ACETOACETYL-COA
type: UnificationXref
id: ACETOACETYL-COA
db: BioCyc

Long-chain specific acyl-CoA dehydrogenase, mitochondrial
type: Complex
component stoichiometry: Protein/15174 Mitochondrion/Stoichiometry/4.0
cellular location: Mitochondrion
component: Isovaleryl-CoA dehydrogenase, mitochondrial

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/CAS 2140-48-9
type: UnificationXref
id: 2140-48-9
db: CAS

Crotonoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Crotonoyl-CoA

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000904 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001345 Mitochondrial Matrix/Stoichiometry/1.0
right: Crotonoyl-CoA
right: Water
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxybutyryl-CoA
name: 3-Hydroxybutyryl-CoA ↔ Crotonoyl-CoA + Water
conversion direction: REVERSIBLE

Reference/PubChem-compound 439214
type: UnificationXref
id: 439214
db: PubChem-compound

1.3.8.8
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000856 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic69 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic70 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001345 Mitochondrion/Stoichiometry/1.0
right: Reduced electron-transfer flavoprotein
right: Crotonoyl-CoA
spontaneous: false
EC number: 1.3.8.8
left: electron-transfer flavoprotein
left: Butyryl-CoA
name: Butyryl-CoA + electron-transfer flavoprotein ↔ Crotonoyl-CoA + Reduced electron-transfer flavoprotein
conversion direction: REVERSIBLE

Compound/PW C000032 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

2.3.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000856 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002007 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
right: 3-Oxohexanoyl-CoA
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.9
left: Acetyl-CoA
left: Butyryl-CoA
name: Acetyl-CoA + Butyryl-CoA → 3-Oxohexanoyl-CoA + Coenzyme A
conversion direction: LEFT_TO_RIGHT

Compound/PW C000904 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxybutyryl-CoA
stoichiometric coefficient: 1.0

Acetoacetyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Acetoacetyl-CoA

Reference/UniProt F1N338
type: UnificationXref
id: F1N338
db: UniProt

Compound/PW C001099 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

SubPathwayInteraction108388
type: Interaction
name: SubPathwayReaction
name: SubPathway108388Reaction
participant: Caproic acid

SubPathwayInteraction108389
type: Interaction
name: SubPathway108389Reaction
name: SubPathwayReaction
participant: Hexanoyl-CoA

Fatty Acid Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108387
pathway component: SubPathwayInteraction108387
xref: Reference/PathWhiz PW000167
xref: Reference/SMPDB SMP0000456
name: SubPathway

SubPathwayInteraction108386
type: Interaction
name: SubPathway108386Reaction
name: SubPathwayReaction
participant: Acetyl-CoA

Reference/HMDB HMDB0001484
type: UnificationXref
id: HMDB0001484
db: HMDB

SubPathwayInteraction108387
type: Interaction
name: SubPathway108387Reaction
name: SubPathwayReaction
participant: Caproic acid

Transport7967
type: Transport
participant stoichiometry: Compound/PW C000412 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000412 Mitochondrial Matrix/Stoichiometry/1.0
right: Caproic acid
spontaneous: false
left: Caproic acid
name: Caproic acid (→) Transport: Bos taurus, Cell, Cytosol to Bos taurus, Cell, Mitochondrial Matrix
conversion direction: LEFT_TO_RIGHT

Hydroxyacyl-CoA dehydrogenase
type: ProteinReference
xref: Reference/UniProt F1N338
organism: Bos taurus

Compound/Generic69 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: electron-transfer flavoprotein
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Acetyl-CoA acetyltransferase, mitochondrial
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Acetyl-CoA acetyltransferase, mitochondrial

Caproic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 30776
xref: Reference/PubChem-compound 8892
xref: Reference/HMDB HMDB0000535
xref: Reference/CAS 142-62-1
xref: Reference/KEGG Compound C01585
xref: Reference/ChemSpider 8552
chemical formula: C6H12O2
molecular weight: 116.08373
structure: ChemicalStructure/PW C000412

Reference/SMPDB SMP0087265
type: UnificationXref
id: SMP0087265
db: SMPDB

Reference/PubChem-compound 449118
type: UnificationXref
id: 449118
db: PubChem-compound

Reaction145818
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002007 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002006 Mitochondrial Matrix/Stoichiometry/1.0
right: 3-Oxohexanoyl-CoA
right: NADH
right: Hydrogen Ion
spontaneous: false
left: 3-Hydroxyhexanoyl-CoA
left: NAD
name: 3-Hydroxyhexanoyl-CoA + NAD ↔ 3-Oxohexanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

Protein/15174 Mitochondrion/Stoichiometry/4.0
type: Stoichiometry
physical entity: Isovaleryl-CoA dehydrogenase, mitochondrial
stoichiometric coefficient: 4.0

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002008 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002006 Mitochondrial Matrix/Stoichiometry/1.0
right: Water
right: (2E)-Hexenoyl-CoA
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxyhexanoyl-CoA
name: 3-Hydroxyhexanoyl-CoA ↔ (2E)-Hexenoyl-CoA + Water
conversion direction: REVERSIBLE

NAD
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: NAD

1.3.8.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002008 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic69 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/Generic70 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001719 Mitochondrion/Stoichiometry/1.0
right: Reduced electron-transfer flavoprotein
right: (2E)-Hexenoyl-CoA
spontaneous: false
EC number: 1.3.8.1
left: electron-transfer flavoprotein
left: Hexanoyl-CoA
name: Hexanoyl-CoA + electron-transfer flavoprotein → (2E)-Hexenoyl-CoA + Reduced electron-transfer flavoprotein
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Compound/PW C000412 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Caproic acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 27648
type: UnificationXref
id: CHEBI:27648
db: ChEBI

3-Hydroxyhexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Hydroxyhexanoyl-CoA

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

3-hydroxyacyl-CoA dehydrogenase type-2
type: Complex
component stoichiometry: Protein/15540 Mitochondrial Matrix/Stoichiometry/4.0
cellular location: Mitochondrial Matrix
component: 3-hydroxyacyl-CoA dehydrogenase type-2

Reference/KEGG Compound C00877
type: UnificationXref
id: C00877
db: KEGG Compound

Reference/PathWhiz PW000022
type: UnificationXref
id: PW000022
db: PathWhiz

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

(2E)-Hexenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: (2E)-Hexenoyl-CoA

Reference/CAS 10018-93-6
type: UnificationXref
id: 10018-93-6
db: CAS

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

3-Hydroxybutyryl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 2871-66-1
xref: Reference/KEGG Compound C03561
xref: Reference/PubChem-compound 440045
xref: Reference/HMDB HMDB0001166
xref: Reference/ChEBI CHEBI 15452
xref: Reference/BioCyc 2-METHYL-3-HYDROXY-BUTYRYL-COA
xref: Reference/ChemSpider 389056
chemical formula: C25H42N7O18P3S
molecular weight: 853.152
structure: ChemicalStructure/PW C000904

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Enoyl-CoA hydratase, mitochondrial
type: Complex
component stoichiometry: Protein/15146 Mitochondrial Matrix/Stoichiometry/6.0
cellular location: Mitochondrial Matrix
component: Enoyl-CoA hydratase, mitochondrial

Water
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Water

Reaction145920
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000904 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001142 Mitochondrial Matrix/Stoichiometry/1.0
right: Acetoacetyl-CoA
right: NADH
right: Hydrogen Ion
spontaneous: false
left: 3-Hydroxybutyryl-CoA
left: NAD
name: 3-Hydroxybutyryl-CoA + NAD → Acetoacetyl-CoA + Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT

Compound/PW C001719 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hexanoyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/CAS 1420-36-6
type: UnificationXref
id: 1420-36-6
db: CAS

Butyryl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Butyryl-CoA

Short-chain specific acyl-CoA dehydrogenase, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Short-chain specific acyl-CoA dehydrogenase, mitochondrial

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Enoyl-CoA hydratase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q4PS76
organism: Bos taurus

Reference/SMPDB SMP0000456
type: UnificationXref
id: SMP0000456
db: SMPDB

Compound/PW C040034 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000412
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCC(O)=O

Compound/PW C001345 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Crotonoyl-CoA
stoichiometric coefficient: 1.0

3-ketoacyl-CoA thiolase, mitochondrial
type: Protein
cellular location: Mitochondrial Matrix
entity reference: 3-ketoacyl-CoA thiolase, mitochondrial

Protein/15401 Mitochondrial Matrix/Stoichiometry/2.0
type: Stoichiometry
physical entity: Hydroxyacyl-CoA dehydrogenase
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0002009
type: UnificationXref
id: HMDB0002009
db: HMDB

Compound/PW C002008 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Hexenoyl-CoA
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001719
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChEBI CHEBI 15345
type: UnificationXref
id: CHEBI:15345
db: ChEBI

3-ketoacyl-CoA thiolase, mitochondrial
type: ProteinReference
xref: Reference/UniProt B4X9P2
organism: Bos taurus

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/PathWhiz PW000005
type: UnificationXref
id: PW000005
db: PathWhiz

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Reference/ChemSpider 4444331
type: UnificationXref
id: 4444331
db: ChemSpider

Reference/PathWhiz PW088284
type: UnificationXref
id: PW088284
db: PathWhiz

ChemicalStructure/PW C002007
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002008
type: ChemicalStructure
structure format: SMILES

Crotonoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Crotonoyl-CoA

Protein/15146 Mitochondrial Matrix/Stoichiometry/6.0
type: Stoichiometry
physical entity: Enoyl-CoA hydratase, mitochondrial
stoichiometric coefficient: 6.0

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Reference/UniProt Q3ZBF6
type: UnificationXref
id: Q3ZBF6
db: UniProt

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Compound/PW C001345 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Crotonoyl-CoA
stoichiometric coefficient: 1.0

Reference/UniProt A7MB45
type: UnificationXref
id: A7MB45
db: UniProt

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/HMDB HMDB0001166
type: UnificationXref
id: HMDB0001166
db: HMDB

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Compound/PW C000856 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Butyryl-CoA
stoichiometric coefficient: 1.0

Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids
type: Pathway
pathway order: PathwayEnzymeReaction/2113562
pathway order: PathwayEnzymeReaction/2113563
pathway order: PathwaySubPathway/108386
pathway order: PathwayEnzymeReaction/2113560
pathway order: PathwaySubPathway/108387
pathway order: PathwayEnzymeReaction/2113561
pathway order: PathwaySubPathway/108388
pathway order: PathwayEnzymeReaction/2113566
pathway order: PathwayEnzymeReaction/2113567
pathway order: PathwayEnzymeReaction/2113564
pathway order: PathwayEnzymeReaction/2113565
pathway order: PathwayEnzymeReaction/2113559
pathway order: PathwayEnzymeReaction/2113557
pathway order: PathwayEnzymeReaction/2113568
pathway order: PathwayEnzymeReaction/2113558
pathway order: PathwayEnzymeReaction/2113569
pathway order: PathwaySubPathway/108389
pathway order: PathwayTransport/2113570
pathway component: ReactionCatalysis135911
pathway component: ReactionCatalysis136408
pathway component: ReactionCatalysis136409
pathway component: ReactionCatalysis135914
pathway component: 4.2.1.17
pathway component: Fatty Acid Elongation in Mitochondria
pathway component: ReactionCatalysis135927
pathway component: Reaction145920
pathway component: 1.3.8.8
pathway component: 2.3.1.9
pathway component: Fatty Acid Biosynthesis
pathway component: Citric Acid Cycle
pathway component: Transport7967
pathway component: ReactionCatalysis136032
pathway component: ReactionCatalysis136033
pathway component: ReactionCatalysis135922
pathway component: ReactionCatalysis135921
pathway component: Reaction145818
pathway component: ReactionCatalysis135926
pathway component: ReactionCatalysis137108
pathway component: 6.2.1.1
pathway component: 1.3.8.1
pathway component: ReactionCatalysis135918
pathway component: ReactionCatalysis135916
pathway component: Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids
xref: Reference/SMPDB SMP0087265
xref: Reference/PathWhiz PW088284
organism: Bos taurus

ReactionCatalysis136032
type: Catalysis
controller: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
controlled: Reaction145920
control type: ACTIVATION

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

ReactionCatalysis136033
type: Catalysis
controller: 3-hydroxyacyl-CoA dehydrogenase type-2
controlled: Reaction145920
control type: ACTIVATION

Hydroxyacyl-CoA dehydrogenase
type: Protein
cellular location: Mitochondrial Matrix
entity reference: Hydroxyacyl-CoA dehydrogenase

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Reference/ChEBI CHEBI 15473
type: UnificationXref
id: CHEBI:15473
db: ChEBI

Acetyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Acetyl-CoA
name: SubPathwayInput

Acyl-CoA synthetase short-chain family member 3, mitochondrial
type: ProteinReference
xref: Reference/UniProt A7MB45
organism: Bos taurus

Reference/UniProt Q4PS76
type: UnificationXref
id: Q4PS76
db: UniProt

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/UniProt Q3SZI8
type: UnificationXref
id: Q3SZI8
db: UniProt