Quantitative metabolomics services for biomarker discovery and validation.
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3-oxo-5- alpha-steroid 4-dehydrogenase 1 Dihydrodiol dehydrogenase 3 UDP- glucuronosyltransferase 1-1 Aromatase Aromatase Aromatase Very-long-chain 3-oxoacyl-CoA reductase Cytochrome P450 11B1, mitochondrial Dihydrodiol dehydrogenase 3 UDP- glucuronosyltransferase 1-1 Hydroxysteroid 11-beta- dehydrogenase 1-like protein Dihydrodiol dehydrogenase 3 11b- Hydroxyandrost- 4-ene-3,17- dione 11b- Hydroxyandrost- 4-ene-3,17- dione Androstenedione NADPH H+ Androstanedione NADP NADH H+ Androsterone NAD Uridine diphosphate glucuronic acid Androsterone glucuronide Uridine 5'-diphosphate O2 19- Hydroxyandrost- 4-ene-3,17- dione H2O O2 19- Oxoandrost-4- ene-3,17- dione H2O O2 Estrone Formic acid H2O Testosterone NAD NADH H+ O2 H+ H2O NADPH H+ NADP Etiocholanedione Etiocholanolone Uridine diphosphate glucuronic acid Etiocholanolone glucuronide Uridine 5'-diphosphate NADP NADPH H+ Adrenosterone NADH H+ NAD Heme Reduced flavoprotein Oxidized flavoprotein Reduced flavoprotein Oxidized flavoprotein Reduced flavoprotein Oxidized flavoprotein Reduced adrenal ferredoxin Oxidized adrenal ferredoxin Heme Heme Heme Mitochondrial Inner Membrane Mitochondrial Outer Membrane Mitochondrial Matrix Mitochondrial Intermembrane Space Endoplasmic Reticulum Membrane Cytosol
Endoplasmic Reticulum Mitochondria SRD5A1 Unknown ERP29 CYP19A1 CYP19A1 CYP19A1 HSD17B12 CYP11B1 Unknown ERP29 HSD11B1L Unknown 11b- Hydroxyandrost- 4-ene-3,17- dione 11b- Hydroxyandrost- 4-ene-3,17- dione Androstenedione NADPH Hydrogen Ion Androstanedione NADP NADH Hydrogen Ion Androsterone NAD Uridine diphosphate glucuronic acid Androsterone glucuronide Uridine 5'-diphosphate Oxygen 19- Hydroxyandrost- 4-ene-3,17- dione Water Oxygen 19- Oxoandrost-4- ene-3,17- dione Water Oxygen Estrone Formic acid Water Testosterone NAD NADH Hydrogen Ion Oxygen Hydrogen Ion Water NADPH Hydrogen Ion NADP Etiocholanedione Etiocholanolone Uridine diphosphate glucuronic acid Etiocholanolone glucuronide Uridine 5'-diphosphate NADP NADPH Hydrogen Ion Adrenosterone NADH Hydrogen Ion NAD Reduced flavoprotein Oxidized flavoprotein Reduced flavoprotein Oxidized flavoprotein Reduced flavoprotein Oxidized flavoprotein Reduced adrenal ferredoxin Oxidized adrenal ferredoxin
SRD5A1 ERP29 CYP19A1 CYP19A1 CYP19A1 HSD17B12 CYP11B1 ERP29 HSD11B1L 4AO3D 4AO3D Adione NADPH H+ Androst NADP NADH H+ Androtn NAD UDPGlcA AGlcA UDP O2 19-Haon H2O O2 19O4e H2O O2 Estrone Formate H2O Oreton NAD NADH H+ O2 H+ H2O NADPH H+ NADP Etiocon Etiocho UDPGlcA Etiocho UDP NADP NADPH H+ Adreno NADH H+ NAD Heme RF OF RF OF RF OF RAF OAF Heme Heme Heme Mitochondrial Inner Membrane Mitochondrial Outer Membrane Mitochondrial Matrix Mitochondrial Intermembrane Space Endoplasmic Reticulum Membrane Cytosol
Endoplasmic Reticulum Mitochondria SRD5A1 ERP29 CYP19A1 CYP19A1 CYP19A1 HSD17B12 CYP11B1 ERP29 HSD11B1L 4AO3D 4AO3D Adione NADPH H+ Androst NADP NADH H+ Androtn NAD UDPGlcA AGlcA UDP O2 19-Haon H2O O2 19O4e H2O O2 Estrone Formate H2O Oreton NAD NADH H+ O2 H+ H2O NADPH H+ NADP Etiocon Etiocho UDPGlcA Etiocho UDP NADP NADPH H+ Adreno NADH H+ NAD RF OF RF OF RF OF RAF OAF