Reference/HMDB HMDB0061363
type: UnificationXref
id: HMDB0061363
db: HMDB

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

SubPathwayInteraction108634
type: Interaction
name: SubPathway108634Reaction
name: SubPathwayReaction
participant: L-Serine

Reference/KEGG Compound C00319
type: UnificationXref
id: C00319
db: KEGG Compound

Sphingosine-1-phosphate phosphatase 1
type: Protein
cellular location: Endoplasmic Reticulum
entity reference: Sphingosine-1-phosphate phosphatase 1

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/KEGG Compound C00550
type: UnificationXref
id: C00550
db: KEGG Compound

Reference/BioCyc DEHYDROSPHINGANINE
type: UnificationXref
id: DEHYDROSPHINGANINE
db: BioCyc

Alkaline ceramidase 3
type: ProteinReference
xref: Reference/UniProt F1M6P3
organism: Rattus norvegicus

Arylsulfatase G
type: ProteinReference
xref: Reference/UniProt Q32KJ9
organism: Rattus norvegicus

CerP(d18:1/18:0)
type: SmallMolecule
cellular location: Cell Membrane
entity reference: CerP(d18:1/18:0)

Sialidase-3
type: ProteinReference
xref: Reference/UniProt Q497C0
organism: Rattus norvegicus

Reference/BioCyc SPHINGO-MYELIN
type: UnificationXref
id: SPHINGO-MYELIN
db: BioCyc

Reference/HMDB HMDB0006752
type: UnificationXref
id: HMDB0006752
db: HMDB

Phosphatidylcholine:ceramide cholinephosphotransferase 1
type: Protein
cellular location: Golgi apparatus
entity reference: Phosphatidylcholine:ceramide cholinephosphotransferase 1

Reference/ChEBI CHEBI 17115
type: UnificationXref
id: CHEBI:17115
db: ChEBI

Sphingosine 1-phosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Sphingosine 1-phosphate

Reference/ChemSpider 388480
type: UnificationXref
id: 388480
db: ChemSpider

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/UniProt Q99P55
type: UnificationXref
id: Q99P55
db: UniProt

Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/CAS 14808-79-8
type: UnificationXref
id: 14808-79-8
db: CAS

Compound/Generic35 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galabiosylceramide-sulfate
stoichiometric coefficient: 1.0

Compound/PW C000043 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine 3',5'-diphosphate
stoichiometric coefficient: 1.0

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Uridine 5'-diphosphate

Reference/BRENDA TISSUE ONTOLOGY BTO 0000759
type: UnificationXref
id: BTO:0000759
db: BRENDA TISSUE ONTOLOGY

Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Adenosine diphosphate

Reference/ChemSpider 959
type: UnificationXref
id: 959
db: ChemSpider

Reference/PubChem-compound 16755624
type: UnificationXref
id: 16755624
db: PubChem-compound

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Compound/PW C000091 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucosylceramide
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

BiologicalState447
type: BioSource
xref: Reference/TAXONOMY 10116
name: Rattus norvegicus, Liver
tissue: Liver

Reference/ChEBI CHEBI 27499
type: UnificationXref
id: CHEBI:27499
db: ChEBI

Reference/CAS 2280-44-6
type: UnificationXref
id: 2280-44-6
db: CAS

ReactionCatalysis138080
type: Catalysis
controller: Arylsulfatase G
controlled: 3.1.6.8
control type: ACTIVATION

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

ReactionCatalysis138082
type: Catalysis
controller: Galactose-3-O-sulfotransferase 1
controlled: 2.8.2.11
control type: ACTIVATION

ReactionCatalysis138081
type: Catalysis
controller: Alpha-N-acetylgalactosaminidase
controlled: 3.2.1.22
control type: ACTIVATION

Phosphorylcholine
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Phosphorylcholine

ReactionCatalysis138084
type: Catalysis
controller: Alkaline ceramidase 3
controlled: 3.5.1.-
control type: ACTIVATION

ReactionCatalysis138083
type: Catalysis
controller: Sialidase-3
controlled: 3.2.1.18
control type: ACTIVATION

Reference/ChemSpider 5736
type: UnificationXref
id: 5736
db: ChemSpider

Reference/PubChem-compound 53477677
type: UnificationXref
id: 53477677
db: PubChem-compound

Reference/PubChem-compound 53477679
type: UnificationXref
id: 53477679
db: PubChem-compound

Reference/PubChem-compound 6031
type: UnificationXref
id: 6031
db: PubChem-compound

Compound/PW C001070 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphinganine 1-phosphate
stoichiometric coefficient: 1.0

Reference/CAS 133-89-1
type: UnificationXref
id: 133-89-1
db: CAS

Reference/PathWhiz PW000157
type: UnificationXref
id: PW000157
db: PathWhiz

Reference/ChemSpider 559277
type: UnificationXref
id: 559277
db: ChemSpider

Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00346
type: UnificationXref
id: C00346
db: KEGG Compound

Reference/KEGG Compound C00588
type: UnificationXref
id: C00588
db: KEGG Compound

Compound/PW C000193 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucose
stoichiometric coefficient: 1.0

Rattus norvegicus
type: BioSource
xref: Reference/TAXONOMY 10116

Reference/CAS 151122-71-3
type: UnificationXref
id: 151122-71-3
db: CAS

Reference/UniProt M0R603
type: UnificationXref
id: M0R603
db: UniProt

Galactosylglycerol
type: SmallMoleculeReference
xref: Reference/ChemSpider 570889
xref: Reference/HMDB HMDB0006790
xref: Reference/ChEBI CHEBI 15754
xref: Reference/PubChem-compound 656504
xref: Reference/KEGG Compound C05401
chemical formula: C9H18O8
molecular weight: 254.10017
structure: ChemicalStructure/PW C002928

1.1.1.102
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001139 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000184 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: 3-Dehydrosphinganine
right: NADP
spontaneous: false
EC number: 1.1.1.102
left: Sphinganine
left: NADPH
name: NADPH + Sphinganine → 3-Dehydrosphinganine + NADP
conversion direction: LEFT_TO_RIGHT

2.7.1.91
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000184 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001070 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Sphinganine 1-phosphate
spontaneous: false
EC number: 2.7.1.91
left: Sphinganine
left: Adenosine triphosphate
name: Adenosine triphosphate + Sphinganine → Adenosine diphosphate + Sphinganine 1-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 24778664
type: UnificationXref
id: 24778664
db: PubChem-compound

Reference/HMDB HMDB0006790
type: UnificationXref
id: HMDB0006790
db: HMDB

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

3.1.3.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000184 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001070 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Endoplasmic Reticulum/Stoichiometry/1.0
right: Adenosine triphosphate
right: Sphinganine
spontaneous: false
EC number: 3.1.3.-
left: Sphinganine 1-phosphate
left: Adenosine diphosphate
name: Adenosine diphosphate + Sphinganine 1-phosphate → Adenosine triphosphate + Sphinganine
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis138068
type: Catalysis
controller: Sphingosine kinase 1
controlled: 2.7.1.138
control type: ACTIVATION

Sphingolipid Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/2114861
pathway order: PathwayEnzymeReaction/2114860
pathway order: PathwayEnzymeReaction/2114843
pathway order: PathwayEnzymeReaction/2114865
pathway order: PathwayEnzymeReaction/2114842
pathway order: PathwayEnzymeReaction/2114864
pathway order: PathwayEnzymeReaction/2114841
pathway order: PathwayEnzymeReaction/2114863
pathway order: PathwayEnzymeReaction/2114840
pathway order: PathwayEnzymeReaction/2114862
pathway order: PathwayEnzymeReaction/2114847
pathway order: PathwayEnzymeReaction/2114846
pathway order: PathwayEnzymeReaction/2114868
pathway order: PathwayEnzymeReaction/2114845
pathway order: PathwayEnzymeReaction/2114867
pathway order: PathwayEnzymeReaction/2114844
pathway order: PathwayEnzymeReaction/2114866
pathway order: PathwayEnzymeReaction/2114849
pathway order: PathwayEnzymeReaction/2114848
pathway order: PathwaySubPathway/108634
pathway order: PathwayEnzymeReaction/2114850
pathway order: PathwayEnzymeReaction/2114854
pathway order: PathwayEnzymeReaction/2114853
pathway order: PathwayEnzymeReaction/2114852
pathway order: PathwayEnzymeReaction/2114851
pathway order: PathwayEnzymeReaction/2114858
pathway order: PathwayEnzymeReaction/2114857
pathway order: PathwayEnzymeReaction/2114856
pathway order: PathwayEnzymeReaction/2114855
pathway order: PathwayEnzymeReaction/2114859
pathway component: 2.3.1.50
pathway component: 1.1.1.102
pathway component: 2.7.1.91
pathway component: 3.1.3.-
pathway component: ReactionCatalysis138068
pathway component: 3.1.3.4
pathway component: ReactionCatalysis138067
pathway component: 4.1.2.27
pathway component: Reaction147796
pathway component: ReactionCatalysis138069
pathway component: ReactionCatalysis138064
pathway component: ReactionCatalysis138063
pathway component: ReactionCatalysis138066
pathway component: ReactionCatalysis138065
pathway component: ReactionCatalysis138060
pathway component: ReactionCatalysis138062
pathway component: ReactionCatalysis138061
pathway component: ReactionCatalysis138079
pathway component: ReactionCatalysis138078
pathway component: 3.5.1.23
pathway component: 2.7.1.138
pathway component: 2.7.8.27
pathway component: 3.1.4.12
pathway component: 2.4.1.45
pathway component: 3.2.1.46
pathway component: 3.2.1.45
pathway component: ReactionCatalysis138075
pathway component: ReactionCatalysis138074
pathway component: ReactionCatalysis138077
pathway component: ReactionCatalysis138076
pathway component: ReactionCatalysis138071
pathway component: ReactionCatalysis138070
pathway component: Glycine and Serine Metabolism
pathway component: ReactionCatalysis138073
pathway component: ReactionCatalysis138072
pathway component: 2.4.1.80
pathway component: 3.2.1.23
pathway component: Reaction147812
pathway component: ReactionCatalysis168770
pathway component: 2.8.2.11
pathway component: 3.1.6.8
pathway component: 3.2.1.22

Compound/PW C000146 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

3.1.3.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001070 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000184 Cell Membrane/Stoichiometry/1.0
right: Phosphate
right: Sphinganine
spontaneous: false
EC number: 3.1.3.4
left: Sphinganine 1-phosphate
left: Water
name: Sphinganine 1-phosphate + Water → Phosphate + Sphinganine
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis138067
type: Catalysis
controller: Alkaline ceramidase
controlled: 3.5.1.23
control type: ACTIVATION

4.1.2.27
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001193 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000149 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001070 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Palmitaldehyde
right: O-Phosphoethanolamine
spontaneous: false
EC number: 4.1.2.27
left: Sphinganine 1-phosphate
name: Sphinganine 1-phosphate → O-Phosphoethanolamine + Palmitaldehyde
conversion direction: LEFT_TO_RIGHT

Reaction147796
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002905 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002313 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Ceramide (d18:1/18:0)
spontaneous: false
left: Dihydroceramide
name: Dihydroceramide ? Ceramide (d18:1/18:0)

ReactionCatalysis138069
type: Catalysis
controller: Phospholipid phosphatase 1
controlled: 3.1.3.4
control type: ACTIVATION

4.1.2.27
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001193 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000188 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000149 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Palmitaldehyde
right: O-Phosphoethanolamine
spontaneous: false
EC number: 4.1.2.27
left: Sphingosine 1-phosphate
name: Sphingosine 1-phosphate → O-Phosphoethanolamine + Palmitaldehyde
conversion direction: LEFT_TO_RIGHT

2.7.1.91
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000188 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000172 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Sphingosine 1-phosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.91
left: Sphingosine
left: Adenosine triphosphate
name: Adenosine triphosphate + Sphingosine → Adenosine diphosphate + Sphingosine 1-phosphate
conversion direction: LEFT_TO_RIGHT

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

3.1.3.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000188 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000172 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Sphingosine
right: Adenosine triphosphate
spontaneous: false
EC number: 3.1.3.-
left: Sphingosine 1-phosphate
left: Adenosine diphosphate
name: Adenosine diphosphate + Sphingosine 1-phosphate → Adenosine triphosphate + Sphingosine
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 20057277
type: UnificationXref
id: 20057277
db: PubChem-compound

Reference/BioCyc PHOSPHATIDYLCHOLINE
type: UnificationXref
id: PHOSPHATIDYLCHOLINE
db: BioCyc

Reference/CAS 1071-23-4
type: UnificationXref
id: 1071-23-4
db: CAS

Compound/PW C000093 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Galactose
stoichiometric coefficient: 1.0

Alkaline ceramidase
type: ProteinReference
xref: Reference/UniProt M0R603
organism: Rattus norvegicus

ReactionCatalysis138064
type: Catalysis
controller: Sphingosine kinase 1
controlled: 2.7.1.91
control type: ACTIVATION

Uridine diphosphate glucose
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Uridine diphosphate glucose

ReactionCatalysis138063
type: Catalysis
controller: Sphingosine-1-phosphate lyase 1
controlled: 4.1.2.27
control type: ACTIVATION

ReactionCatalysis138066
type: Catalysis
controller: Phospholipid phosphatase 1
controlled: 3.1.3.4
control type: ACTIVATION

ReactionCatalysis138065
type: Catalysis
controller: Sphingosine-1-phosphate phosphatase 1
controlled: 3.1.3.-
control type: ACTIVATION

ReactionCatalysis138060
type: Catalysis
controller: Phospholipid phosphatase 1
controlled: 3.1.3.4
control type: ACTIVATION

Compound/PW C002240 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lactosylceramide (d18:1/12:0)
stoichiometric coefficient: 1.0

ReactionCatalysis138062
type: Catalysis
controller: Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2
controlled: Reaction147796
control type: ACTIVATION

ReactionCatalysis138061
type: Catalysis
controller: Sphingosine-1-phosphate lyase 1
controlled: 4.1.2.27
control type: ACTIVATION

Reference/BioCyc PALMITALDEHYDE
type: UnificationXref
id: PALMITALDEHYDE
db: BioCyc

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

ReactionCatalysis138079
type: Catalysis
controller: Galactose-3-O-sulfotransferase 1
controlled: 2.8.2.11
control type: ACTIVATION

ReactionCatalysis138078
type: Catalysis
controller: Beta-1,4-galactosyltransferase 6
controlled: Reaction147812
control type: ACTIVATION

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

NADPH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADPH

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/ChEBI CHEBI 16189
type: UnificationXref
id: CHEBI:16189
db: ChEBI

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Phosphatidylcholine:ceramide cholinephosphotransferase 1
type: ProteinReference
xref: Reference/UniProt Q7TSX5
organism: Rattus norvegicus

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
type: ProteinReference
xref: Reference/UniProt Q5EZ72
organism: Rattus norvegicus

ReactionCatalysis138075
type: Catalysis
controller: Glucosylceramidase
controlled: 3.2.1.45
control type: ACTIVATION

ReactionCatalysis138074
type: Catalysis
controller: Galactosylceramidase
controlled: 3.2.1.46
control type: ACTIVATION

2-hydroxyacylsphingosine 1-beta-galactosyltransferase
type: ProteinReference
xref: Reference/UniProt Q09426
organism: Rattus norvegicus

ReactionCatalysis138077
type: Catalysis
controller: Unknown
controlled: 3.2.1.23
control type: ACTIVATION

Arylsulfatase G
type: Protein
cellular location: Lysosome
entity reference: Arylsulfatase G

ReactionCatalysis138076
type: Catalysis
controller: Ceramide glucosyltransferase
controlled: 2.4.1.80
control type: ACTIVATION

ReactionCatalysis138071
type: Catalysis
controller: Phosphatidylcholine:ceramide cholinephosphotransferase 1
controlled: 2.7.8.27
control type: ACTIVATION

ReactionCatalysis138070
type: Catalysis
controller: Sphingosine-1-phosphate phosphatase 1
controlled: 3.1.3.-
control type: ACTIVATION

ReactionCatalysis138073
type: Catalysis
controller: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase
controlled: 2.4.1.45
control type: ACTIVATION

ReactionCatalysis138072
type: Catalysis
controller: Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
controlled: 3.1.4.12
control type: ACTIVATION

Dihydroceramide
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 31488
xref: Reference/ChemSpider 21436314
xref: Reference/HMDB HMDB0006752
xref: Reference/PubChem-compound 16755624
xref: Reference/KEGG Compound C12126
chemical formula: C19H39NO3
molecular weight: 329.293
structure: ChemicalStructure/PW C002905

Compound/PW C000188 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphingosine 1-phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 388895
type: UnificationXref
id: 388895
db: ChemSpider

ChemicalStructure/PW C040684
type: ChemicalStructure
structure format: SMILES
structure data: COC1=C(OC)C=C2C(=O)C(CC3CCNCC3)CC2=C1

Dihydroceramide
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroceramide

Compound/PW C001070 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphinganine 1-phosphate
stoichiometric coefficient: 1.0

Sphinganine 1-phosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Sphinganine 1-phosphate

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

Reference/ChEBI CHEBI 16393
type: UnificationXref
id: CHEBI:16393
db: ChEBI

Reference/KEGG Compound C00015
type: UnificationXref
id: C00015
db: KEGG Compound

Compound/PW C000172 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphingosine
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0010708
type: UnificationXref
id: HMDB0010708
db: HMDB

Compound/PW C001070 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphinganine 1-phosphate
stoichiometric coefficient: 1.0

Compound/PW C001139 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Dehydrosphinganine
stoichiometric coefficient: 1.0

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Compound/PW C000184 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphinganine
stoichiometric coefficient: 1.0

Galactosylceramidase
type: ProteinReference
xref: Reference/UniProt Q5YKG1
organism: Rattus norvegicus

Reference/HMDB HMDB0010701
type: UnificationXref
id: HMDB0010701
db: HMDB

Uridine diphosphate glucose
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Uridine diphosphate glucose

Glucosylceramidase
type: ProteinReference
xref: Reference/UniProt B2RYC9
organism: Rattus norvegicus

Reference/KEGG Compound C00029
type: UnificationXref
id: C00029
db: KEGG Compound

ReactionCatalysis138057
type: Catalysis
controller: Dehydrogenase/reductase SDR family member 7B
controlled: 1.1.1.102
control type: ACTIVATION

Lactosylceramide (d18:1/12:0)
type: SmallMolecule
cellular location: Cytosol
entity reference: Lactosylceramide (d18:1/12:0)

ReactionCatalysis138059
type: Catalysis
controller: Sphingosine-1-phosphate phosphatase 1
controlled: 3.1.3.-
control type: ACTIVATION

ReactionCatalysis138058
type: Catalysis
controller: Sphingosine kinase 1
controlled: 2.7.1.91
control type: ACTIVATION

Reference/CAS 59-23-4
type: UnificationXref
id: 59-23-4
db: CAS

Reference/KEGG Compound C02686
type: UnificationXref
id: C02686
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Galactose-3-O-sulfotransferase 1
type: ProteinReference
xref: Reference/UniProt Q5PQK7
organism: Rattus norvegicus

Ceramide glucosyltransferase
type: ProteinReference
xref: Reference/UniProt O55149
organism: Rattus norvegicus

Reference/ChEBI CHEBI 73144
type: UnificationXref
id: CHEBI:73144
db: ChEBI

Beta-1,4-galactosyltransferase 6
type: ProteinReference
xref: Reference/UniProt O88419
organism: Rattus norvegicus

Reference/BioCyc PHOSPHORYL-CHOLINE
type: UnificationXref
id: PHOSPHORYL-CHOLINE
db: BioCyc

Ceramide (d18:1/18:0)
type: SmallMolecule
cellular location: Lysosome
entity reference: Ceramide (d18:1/18:0)

Reference/CAS 482-67-7
type: UnificationXref
id: 482-67-7
db: CAS

Compound/PW C000172 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphingosine
stoichiometric coefficient: 1.0

NADP
type: SmallMolecule
cellular location: Cytosol
entity reference: NADP

Reference/KEGG Compound C12126
type: UnificationXref
id: C12126
db: KEGG Compound

Galabiosylceramide-sulfate
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Galabiosylceramide-sulfate

Sphinganine
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Sphinganine

ChemicalStructure/PW C006709
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00154
type: UnificationXref
id: C00154
db: KEGG Compound

ChemicalStructure/PW C001139
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCC(=O)[C@@H](N)CO

Compound/PW C001034 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C01120
type: UnificationXref
id: C01120
db: KEGG Compound

Reference/KEGG Compound C00031
type: UnificationXref
id: C00031
db: KEGG Compound

Reference/KEGG Compound C00157
type: UnificationXref
id: C00157
db: KEGG Compound

Compound/PW C006716 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactosylceramide (d18:1/16:0)
stoichiometric coefficient: 1.0

Compound/PW C002212 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galabiosylceramide (d18:1/22:0)
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 31488
type: UnificationXref
id: CHEBI:31488
db: ChEBI

Reference/HMDB HMDB0001348
type: UnificationXref
id: HMDB0001348
db: HMDB

Reference/CAS 104404-17-3
type: UnificationXref
id: 104404-17-3
db: CAS

Adenosine triphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Adenosine triphosphate

ChemicalStructure/PW C000172
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCC\C=C\C(O)C(N)CO

Sphingosine kinase 1
type: Protein
cellular location: Cytosol
entity reference: Sphingosine kinase 1

Compound/PW C000414 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Adenosine triphosphate

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/HMDB HMDB0000252
type: UnificationXref
id: HMDB0000252
db: HMDB

Reference/PubChem-compound 5283583
type: UnificationXref
id: 5283583
db: PubChem-compound

Compound/PW C000017 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-O-Sulfogalactosylceramide (d18:1/24:0)
stoichiometric coefficient: 1.0

Galactosylglycerol
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Galactosylglycerol

Water
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Water

ChemicalStructure/PW C006716
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0004866
type: UnificationXref
id: HMDB0004866
db: HMDB

Reference/HMDB HMDB0000024
type: UnificationXref
id: HMDB0000024
db: HMDB

ChemicalStructure/PW C001031
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000184
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO

Water
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Water

Sphinganine
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Sphinganine

Reference/HMDB HMDB0000269
type: UnificationXref
id: HMDB0000269
db: HMDB

ChemicalStructure/PW C000188
type: ChemicalStructure
structure format: SMILES

Uridine 5'-diphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17659
xref: Reference/PubChem-compound 6031
xref: Reference/CAS 58-98-0
xref: Reference/HMDB HMDB0000295
xref: Reference/KEGG Compound C00015
xref: Reference/ChemSpider 5809
xref: Reference/BioCyc UDP
chemical formula: C9H14N2O12P2
molecular weight: 404.0022
structure: ChemicalStructure/PW C000201

Reference/PubChem-compound 5283588
type: UnificationXref
id: 5283588
db: PubChem-compound

ChemicalStructure/PW C002240
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000140
type: UnificationXref
id: HMDB0000140
db: HMDB

Reference/HMDB HMDB0000143
type: UnificationXref
id: HMDB0000143
db: HMDB

Compound/PW C000120 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Serine
stoichiometric coefficient: 1.0

Glucosylceramidase
type: Protein
cellular location: Lysosome
entity reference: Glucosylceramidase

Phosphoadenosine phosphosulfate
type: SmallMoleculeReference
xref: Reference/BioCyc PAPS
xref: Reference/HMDB HMDB0001134
xref: Reference/CAS 482-67-7
xref: Reference/ChemSpider 9799
xref: Reference/KEGG Compound C00053
xref: Reference/PubChem-compound 10214
xref: Reference/ChEBI CHEBI 17980
chemical formula: C10H15N5O13P2S
molecular weight: 506.98624
structure: ChemicalStructure/PW C000886

Reference/UniProt Q497C0
type: UnificationXref
id: Q497C0
db: UniProt

Reference/ChEBI CHEBI 28061
type: UnificationXref
id: CHEBI:28061
db: ChEBI

Reference/ChemSpider 140102
type: UnificationXref
id: 140102
db: ChemSpider

Reference/ChEBI CHEBI 18132
type: UnificationXref
id: CHEBI:18132
db: ChEBI

ChemicalStructure/PW C001118
type: ChemicalStructure
structure format: SMILES
structure data: OS(O)(=O)=O

Reference/PubChem-compound 644260
type: UnificationXref
id: 644260
db: PubChem-compound

ChemicalStructure/PW C000149
type: ChemicalStructure
structure format: SMILES
structure data: NCCOP(O)(O)=O

Reference/KEGG Compound C00054
type: UnificationXref
id: C00054
db: KEGG Compound

Reference/KEGG Compound C00053
type: UnificationXref
id: C00053
db: KEGG Compound

Reference/CAS 16105-69-4
type: UnificationXref
id: 16105-69-4
db: CAS

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/BioCyc CERAMIDE
type: UnificationXref
id: CERAMIDE
db: BioCyc

Reference/KEGG Compound C00059
type: UnificationXref
id: C00059
db: KEGG Compound

Reference/CAS 19794-97-9
type: UnificationXref
id: 19794-97-9
db: CAS

Compound/PW C001420 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Sphinganine 1-phosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Sphinganine 1-phosphate

Reference/HMDB HMDB0000277
type: UnificationXref
id: HMDB0000277
db: HMDB

Water
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Water

ChemicalStructure/PW C002212
type: ChemicalStructure
structure format: SMILES

Dehydrogenase/reductase SDR family member 7B
type: ProteinReference
xref: Reference/UniProt A4GWE3
organism: Rattus norvegicus

3-O-Sulfogalactosylceramide (d18:1/24:0)
type: SmallMolecule
cellular location: Lysosome
entity reference: 3-O-Sulfogalactosylceramide (d18:1/24:0)

Sphingosine kinase 1
type: ProteinReference
xref: Reference/UniProt Q642F6
organism: Rattus norvegicus

Alpha-N-acetylgalactosaminidase
type: ProteinReference
xref: Reference/UniProt Q66H12
organism: Rattus norvegicus

Reference/HMDB HMDB0001480
type: UnificationXref
id: HMDB0001480
db: HMDB

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Palmityl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Palmityl-CoA

Reference/KEGG Compound C00065
type: UnificationXref
id: C00065
db: KEGG Compound

Reference/PubChem-compound 10214
type: UnificationXref
id: 10214
db: PubChem-compound

Reference/CAS 107-73-3
type: UnificationXref
id: 107-73-3
db: CAS

Reference/HMDB HMDB0001134
type: UnificationXref
id: HMDB0001134
db: HMDB

ChemicalStructure/PW C000043
type: ChemicalStructure
structure format: SMILES

Sphingosine-1-phosphate phosphatase 1
type: ProteinReference
xref: Reference/UniProt Q99P55
organism: Rattus norvegicus

Reference/UniProt O88419
type: UnificationXref
id: O88419
db: UniProt

Reference/KEGG Compound C00195
type: UnificationXref
id: C00195
db: KEGG Compound

Sphingosine-1-phosphate lyase 1
type: ProteinReference
xref: Reference/UniProt Q8CHN6
organism: BiologicalState447

Reference/ChemSpider 21436314
type: UnificationXref
id: 21436314
db: ChemSpider

Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2
type: ProteinReference
xref: Reference/UniProt Q564G3
organism: BiologicalState447

Reference/HMDB HMDB0000286
type: UnificationXref
id: HMDB0000286
db: HMDB

Reference/UniProt Q8K594
type: UnificationXref
id: Q8K594
db: UniProt

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Compound/PW C002905 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroceramide
stoichiometric coefficient: 1.0

Reference/BioCyc GLUCOSYL CERAMIDE
type: UnificationXref
id: GLUCOSYL_CERAMIDE
db: BioCyc

Compound/PW C001031 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmityl-CoA
stoichiometric coefficient: 1.0

Alkaline ceramidase 3
type: Protein
cellular location: Cytosol
entity reference: Alkaline ceramidase 3

Galactosylceramide (d18:1/16:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Galactosylceramide (d18:1/16:0)

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/CAS 58-98-0
type: UnificationXref
id: 58-98-0
db: CAS

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Galactosylceramide (d18:1/16:0)
type: SmallMolecule
cellular location: Lysosome
entity reference: Galactosylceramide (d18:1/16:0)

Reference/KEGG Compound C05401
type: UnificationXref
id: C05401
db: KEGG Compound

Sphinganine
type: SmallMolecule
cellular location: Cytosol
entity reference: Sphinganine

Reference/KEGG Compound C01290
type: UnificationXref
id: C01290
db: KEGG Compound

Sphingosine 1-phosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Sphingosine 1-phosphate

Phosphorylcholine
type: SmallMoleculeReference
xref: Reference/CAS 107-73-3
xref: Reference/HMDB HMDB0001565
xref: Reference/BioCyc PHOSPHORYL-CHOLINE
xref: Reference/PubChem-compound 1014
xref: Reference/ChEBI CHEBI 18132
xref: Reference/KEGG Compound C00588
xref: Reference/ChemSpider 989
chemical formula: C5H15NO4P
molecular weight: 184.07387
structure: ChemicalStructure/PW C001202

ChemicalStructure/PW C000091
type: ChemicalStructure
structure format: SMILES

Sphingosine
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Sphingosine

Glucosylceramide
type: SmallMolecule
cellular location: Lysosome
entity reference: Glucosylceramide

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0000295
type: UnificationXref
id: HMDB0000295
db: HMDB

Reference/HMDB HMDB0001383
type: UnificationXref
id: HMDB0001383
db: HMDB

Reference/ChemSpider 5809
type: UnificationXref
id: 5809
db: ChemSpider

ChemicalStructure/PW C000093
type: ChemicalStructure
structure format: SMILES

Compound/PW C006709 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: CerP(d18:1/18:0)
stoichiometric coefficient: 1.0

Compound/PW C002313 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ceramide (d18:1/18:0)
stoichiometric coefficient: 1.0

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Beta-1,4-galactosyltransferase 6
type: Protein
cellular location: Golgi apparatus
entity reference: Beta-1,4-galactosyltransferase 6

Compound/PW C040684 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-acetylneuraminyl-Galactosylceramide
stoichiometric coefficient: 1.0

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/UniProt Q09426
type: UnificationXref
id: Q09426
db: UniProt

Compound/PW C002928 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactosylglycerol
stoichiometric coefficient: 1.0

PC(15:0/18:2(9Z,12Z))
type: SmallMoleculeReference
xref: Reference/ChemSpider 24766615
xref: Reference/PubChem-compound 24778664
xref: Reference/HMDB HMDB0007940
xref: Reference/KEGG Compound C00157
xref: Reference/BioCyc PHOSPHATIDYLCHOLINE
chemical formula: C41H78NO8P
molecular weight: 743.5465
structure: ChemicalStructure/PW C003990

Reference/ChEBI CHEBI 4167
type: UnificationXref
id: CHEBI:4167
db: ChEBI

L-Serine
type: SmallMolecule
entity reference: L-Serine
name: SubPathwayOutput

ChemicalStructure/PW C001070
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000061
type: UnificationXref
id: HMDB0000061
db: HMDB

L-Serine
type: SmallMoleculeReference
xref: Reference/ChemSpider 5736
xref: Reference/ChEBI CHEBI 17115
xref: Reference/CAS 56-45-1
xref: Reference/KEGG Compound C00065
xref: Reference/PubChem-compound 5951
xref: Reference/HMDB HMDB0000187
xref: Reference/BioCyc SER
chemical formula: C3H7NO3
molecular weight: 105.042595
structure: ChemicalStructure/PW C000120

Reference/HMDB HMDB0000187
type: UnificationXref
id: HMDB0000187
db: HMDB

ChemicalStructure/PW C001193
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCC=O

Reference/PubChem-compound 984
type: UnificationXref
id: 984
db: PubChem-compound

Reference/UniProt Q7TSX5
type: UnificationXref
id: Q7TSX5
db: UniProt

Galactosylceramide (d18:1/16:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Galactosylceramide (d18:1/16:0)

Compound/PW C006716 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactosylceramide (d18:1/16:0)
stoichiometric coefficient: 1.0

Alpha-N-acetylgalactosaminidase
type: Protein
cellular location: Lysosome
entity reference: Alpha-N-acetylgalactosaminidase

PC(15:0/18:2(9Z,12Z))
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: PC(15:0/18:2(9Z,12Z))

ReactionCatalysis168770
type: Catalysis
controller: 5-aminolevulinate synthase, nonspecific, mitochondrial
controlled: 2.3.1.50
control type: ACTIVATION

ChemicalStructure/PW C000077
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O

Reference/ChemSpider 4953605
type: UnificationXref
id: 4953605
db: ChemSpider

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/KEGG Compound C01190
type: UnificationXref
id: C01190
db: KEGG Compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/ChemSpider 990
type: UnificationXref
id: 990
db: ChemSpider

Glucosylceramide
type: SmallMolecule
cellular location: Cytosol
entity reference: Glucosylceramide

Reference/HMDB HMDB0007940
type: UnificationXref
id: HMDB0007940
db: HMDB

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Uridine 5'-diphosphate

Reference/BioCyc CYTOLIPIN H
type: UnificationXref
id: CYTOLIPIN_H
db: BioCyc

Compound/PW C001034 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001040
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000193
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5283560
type: UnificationXref
id: 5283560
db: PubChem-compound

Phosphoadenosine phosphosulfate
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Phosphoadenosine phosphosulfate

Compound/PW C001316 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/UniProt A4GWE3
type: UnificationXref
id: A4GWE3
db: UniProt

Reference/ChemSpider 989
type: UnificationXref
id: 989
db: ChemSpider

Compound/PW C001420 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Compound/PW C006716 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactosylceramide (d18:1/16:0)
stoichiometric coefficient: 1.0

SM(d18:1/18:0)
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: SM(d18:1/18:0)

Compound/PW C000077 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glucose
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5283565
type: UnificationXref
id: 5283565
db: PubChem-compound

Phospholipid phosphatase 1
type: ProteinReference
xref: Reference/UniProt Q8K594
organism: Rattus norvegicus

Compound/PW C001193 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmitaldehyde
stoichiometric coefficient: 1.0

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

O-Phosphoethanolamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000224
xref: Reference/BioCyc PHOSPHORYL-ETHANOLAMINE
xref: Reference/ChemSpider 990
xref: Reference/PubChem-compound 1015
xref: Reference/KEGG Compound C00346
xref: Reference/ChEBI CHEBI 17553
xref: Reference/CAS 1071-23-4
chemical formula: C2H8NO4P
molecular weight: 141.01909
structure: ChemicalStructure/PW C000149

Reference/BioCyc PHOSPHORYL-ETHANOLAMINE
type: UnificationXref
id: PHOSPHORYL-ETHANOLAMINE
db: BioCyc

Reference/ChemSpider 4446696
type: UnificationXref
id: 4446696
db: ChemSpider

Reference/PubChem-compound 1014
type: UnificationXref
id: 1014
db: PubChem-compound

Reference/PubChem-compound 1015
type: UnificationXref
id: 1015
db: PubChem-compound

Sulfate
type: SmallMoleculeReference
xref: Reference/BioCyc NH42SO4
xref: Reference/CAS 14808-79-8
xref: Reference/PubChem-compound 1117
xref: Reference/HMDB HMDB0001448
xref: Reference/ChemSpider 1085
xref: Reference/KEGG Compound C00059
xref: Reference/ChEBI CHEBI 16189
chemical formula: H2O4S
molecular weight: 97.96738
structure: ChemicalStructure/PW C001118

Compound/PW C000414 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Galabiosylceramide (d18:1/22:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0004836
xref: Reference/ChemSpider 16744853
xref: Reference/PubChem-compound 20057277
xref: Reference/CAS 77538-38-6
xref: Reference/KEGG Compound C06126
chemical formula: C52H99NO13
molecular weight: 945.7117
structure: ChemicalStructure/PW C002212

Ceramide (d18:1/18:0)
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Ceramide (d18:1/18:0)

Glucosylceramide
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Glucosylceramide

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/PubChem-compound 656504
type: UnificationXref
id: 656504
db: PubChem-compound

Ceramide (d18:1/18:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Ceramide (d18:1/18:0)

Sphinganine 1-phosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Sphinganine 1-phosphate

Compound/PW C000886 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoadenosine phosphosulfate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Compound/PW C000143 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/CAS 629-80-1
type: UnificationXref
id: 629-80-1
db: CAS

D-Glucose
type: SmallMolecule
cellular location: Lysosome
entity reference: D-Glucose

Alkaline ceramidase
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Alkaline ceramidase

Compound/PW C001118 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sulfate
stoichiometric coefficient: 1.0

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Adenosine 3',5'-diphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17985
xref: Reference/CAS 1053-73-2
xref: Reference/PubChem-compound 159296
xref: Reference/ChemSpider 140102
xref: Reference/BioCyc 3-5-ADP
xref: Reference/KEGG Compound C00054
xref: Reference/HMDB HMDB0000061
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C000043

Reference/BioCyc PALMITYL-COA
type: UnificationXref
id: PALMITYL-COA
db: BioCyc

5-aminolevulinate synthase, nonspecific, mitochondrial
type: Protein
cellular location: Cytosol
entity reference: 5-aminolevulinate synthase, nonspecific, mitochondrial

Reference/ChemSpider 4446678
type: UnificationXref
id: 4446678
db: ChemSpider

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Lysosome
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005764

Reference/ChemSpider 4446673
type: UnificationXref
id: 4446673
db: ChemSpider

Sphingosine kinase 1
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Sphingosine kinase 1

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/PubChem-compound 439853
type: UnificationXref
id: 439853
db: PubChem-compound

Reference/UniProt Q66H12
type: UnificationXref
id: Q66H12
db: UniProt

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Ceramide (d18:1/18:0)
type: SmallMoleculeReference
xref: Reference/ChemSpider 4446678
xref: Reference/KEGG Compound C00195
xref: Reference/CAS 104404-17-3
xref: Reference/PubChem-compound 5283565
xref: Reference/HMDB HMDB0004950
xref: Reference/BioCyc CERAMIDE
xref: Reference/ChEBI CHEBI 72961
chemical formula: C36H71NO3
molecular weight: 565.5434
structure: ChemicalStructure/PW C002313

Reference/UniProt Q564G3
type: UnificationXref
id: Q564G3
db: UniProt

Compound/PW C000193 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucose
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5353955
type: UnificationXref
id: 5353955
db: PubChem-compound

Phosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Phosphate

3-O-Sulfogalactosylceramide (d18:1/24:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000024
xref: Reference/ChemSpider 4953605
xref: Reference/ChEBI CHEBI 60361
xref: Reference/BioCyc GALACTOSYLCERAMIDE-SULFATE
xref: Reference/PubChem-compound 6451121
xref: Reference/CAS 151122-71-3
xref: Reference/KEGG Compound C06125
chemical formula: C48H93NO11S
molecular weight: 891.6469
structure: ChemicalStructure/PW C000017

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

3-O-Sulfogalactosylceramide (d18:1/24:0)
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: 3-O-Sulfogalactosylceramide (d18:1/24:0)

Reference/PathWhiz PW088356
type: UnificationXref
id: PW088356
db: PathWhiz

Reference/BioCyc SER
type: UnificationXref
id: SER
db: BioCyc

Sphingosine
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Sphingosine

Compound/PW C002313 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ceramide (d18:1/18:0)
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000201
type: ChemicalStructure
structure format: SMILES

Galabiosylceramide (d18:1/22:0)
type: SmallMolecule
cellular location: Lysosome
entity reference: Galabiosylceramide (d18:1/22:0)

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Reference/BioCyc 3-5-ADP
type: UnificationXref
id: 3-5-ADP
db: BioCyc

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H29N7O17P3
molecular weight: 744.08325
structure: ChemicalStructure/PW C000143

Reference/BioCyc CPD-649
type: UnificationXref
id: CPD-649
db: BioCyc

Reference/ChEBI CHEBI 37550
type: UnificationXref
id: CHEBI:37550
db: ChEBI

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/CAS 4682-48-8
type: UnificationXref
id: 4682-48-8
db: CAS

Reference/CAS 1053-73-2
type: UnificationXref
id: 1053-73-2
db: CAS

Ceramide glucosyltransferase
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Ceramide glucosyltransferase

Reference/ChEBI CHEBI 15525
type: UnificationXref
id: CHEBI:15525
db: ChEBI

Phospholipid phosphatase 1
type: Protein
cellular location: Cell Membrane
entity reference: Phospholipid phosphatase 1

Sphinganine 1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Sphinganine 1-phosphate

Carbon dioxide
type: SmallMolecule
cellular location: Cytosol
entity reference: Carbon dioxide

Sphingosine-1-phosphate phosphatase 1
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Sphingosine-1-phosphate phosphatase 1

Reference/ChemSpider 570889
type: UnificationXref
id: 570889
db: ChemSpider

Compound/PW C001202 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphorylcholine
stoichiometric coefficient: 1.0

Uridine diphosphate glucose
type: SmallMoleculeReference
xref: Reference/BioCyc UDP-GLUCOSE
xref: Reference/KEGG Compound C00029
xref: Reference/PubChem-compound 53477679
xref: Reference/CAS 133-89-1
xref: Reference/HMDB HMDB0000286
chemical formula: C15H24N2O17P2
molecular weight: 566.055
structure: ChemicalStructure/PW C000193

Reference/BioCyc UDP-GLUCOSE
type: UnificationXref
id: UDP-GLUCOSE
db: BioCyc

ChemicalStructure/PW C002313
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Reference/UniProt Q642F6
type: UnificationXref
id: Q642F6
db: UniProt

Reference/UniProt Q8CHN6
type: UnificationXref
id: Q8CHN6
db: UniProt

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Reference/GENE ONTOLOGY GO 0005886
type: UnificationXref
id: GO:0005886
db: GENE ONTOLOGY

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Galactosylceramidase
type: Protein
cellular location: Lysosome
entity reference: Galactosylceramidase

Reference/GENE ONTOLOGY GO 0005764
type: UnificationXref
id: GO:0005764
db: GENE ONTOLOGY

D-Glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000122
xref: Reference/PubChem-compound 5793
xref: Reference/CAS 2280-44-6
xref: Reference/ChemSpider 5589
xref: Reference/ChEBI CHEBI 4167
xref: Reference/BioCyc GLC
xref: Reference/KEGG Compound C00031
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000077

SM(d18:1/18:0)
type: SmallMoleculeReference
xref: Reference/CAS 85187-10-6
xref: Reference/ChemSpider 4446701
xref: Reference/HMDB HMDB0001348
xref: Reference/BioCyc SPHINGO-MYELIN
xref: Reference/ChEBI CHEBI 17636
xref: Reference/KEGG Compound C00550
xref: Reference/PubChem-compound 5283588
chemical formula: C41H84N2O6P
molecular weight: 731.6067
structure: ChemicalStructure/PW C001040

Compound/PW C000184 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphinganine
stoichiometric coefficient: 1.0

Sphingosine kinase 1
type: Protein
cellular location: Cell Membrane
entity reference: Sphingosine kinase 1

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc GLC
type: UnificationXref
id: GLC
db: BioCyc

Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/UniProt O55149
type: UnificationXref
id: O55149
db: UniProt

Reference/ChemSpider 9799
type: UnificationXref
id: 9799
db: ChemSpider

ChemicalStructure/PW C000017
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc SPHINGOSINE
type: UnificationXref
id: SPHINGOSINE
db: BioCyc

Reference/CAS 1763-10-6
type: UnificationXref
id: 1763-10-6
db: CAS

Liver
type: TissueVocabulary
xref: Reference/BRENDA TISSUE ONTOLOGY BTO 0000759

Lactosylceramide (d18:1/12:0)
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Lactosylceramide (d18:1/12:0)

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Adenosine triphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Adenosine triphosphate

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Reference/HMDB HMDB0000224
type: UnificationXref
id: HMDB0000224
db: HMDB

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 159296
type: UnificationXref
id: 159296
db: PubChem-compound

Reference/UniProt F1M6P3
type: UnificationXref
id: F1M6P3
db: UniProt

Reference/UniProt Q5YKG1
type: UnificationXref
id: Q5YKG1
db: UniProt

Glycine and Serine Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108634
pathway component: SubPathwayInteraction108634
xref: Reference/PathWhiz PW000157
xref: Reference/SMPDB SMP0000004
name: SubPathway

Reference/HMDB HMDB0001551
type: UnificationXref
id: HMDB0001551
db: HMDB

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Compound/PW C002905 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroceramide
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
type: Protein
cellular location: Golgi apparatus
entity reference: Ectonucleotide pyrophosphatase/phosphodiesterase family member 7

3-Dehydrosphinganine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 439853
xref: Reference/ChEBI CHEBI 17862
xref: Reference/ChemSpider 388895
xref: Reference/KEGG Compound C02934
xref: Reference/HMDB HMDB0001480
xref: Reference/CAS 16105-69-4
xref: Reference/BioCyc DEHYDROSPHINGANINE
chemical formula: C18H37NO2
molecular weight: 299.28244
structure: ChemicalStructure/PW C001139

D-Galactose
type: SmallMolecule
cellular location: Lysosome
entity reference: D-Galactose

CerP(d18:1/18:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 73144
xref: Reference/PubChem-compound 5283583
xref: Reference/ChemSpider 4446696
xref: Reference/HMDB HMDB0010701
chemical formula: C36H72NO6P
molecular weight: 645.5097
structure: ChemicalStructure/PW C006709

Reference/PubChem-compound 5951
type: UnificationXref
id: 5951
db: PubChem-compound

Sialidase-3
type: Protein
cellular location: Endoplasmic Reticulum
entity reference: Sialidase-3

Reference/KEGG Compound C06124
type: UnificationXref
id: C06124
db: KEGG Compound

Reference/HMDB HMDB0001565
type: UnificationXref
id: HMDB0001565
db: HMDB

ChemicalStructure/PW C001202
type: ChemicalStructure
structure format: SMILES
structure data: C[N+](C)(C)CCOP(O)(O)=O

Reference/PubChem-compound 1117
type: UnificationXref
id: 1117
db: PubChem-compound

Sulfate
type: SmallMolecule
cellular location: Lysosome
entity reference: Sulfate

Reference/HMDB HMDB0004836
type: UnificationXref
id: HMDB0004836
db: HMDB

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001448
type: UnificationXref
id: HMDB0001448
db: HMDB

Reference/SMPDB SMP0087337
type: UnificationXref
id: SMP0087337
db: SMPDB

Reference/HMDB HMDB0004950
type: UnificationXref
id: HMDB0004950
db: HMDB

Compound/PW C002313 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ceramide (d18:1/18:0)
stoichiometric coefficient: 1.0

Compound/PW C000201 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

Sphingosine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5353955
xref: Reference/KEGG Compound C00319
xref: Reference/BioCyc SPHINGOSINE
xref: Reference/ChEBI CHEBI 16393
xref: Reference/CAS 123-78-4
xref: Reference/ChemSpider 4510275
xref: Reference/HMDB HMDB0000252
chemical formula: C18H37NO2
molecular weight: 299.28244
structure: ChemicalStructure/PW C000172

Compound/PW C000017 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-O-Sulfogalactosylceramide (d18:1/24:0)
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15754
type: UnificationXref
id: CHEBI:15754
db: ChEBI

Galactosylceramide (d18:1/16:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0010708
xref: Reference/PubChem-compound 53480652
xref: Reference/ChemSpider 24765744
xref: Reference/KEGG Compound C02686
chemical formula: C40H77NO8
molecular weight: 699.56494
structure: ChemicalStructure/PW C006716

Reference/KEGG Compound C06125
type: UnificationXref
id: C06125
db: KEGG Compound

Reference/ChEBI CHEBI 72961
type: UnificationXref
id: CHEBI:72961
db: ChEBI

Reference/KEGG Compound C06126
type: UnificationXref
id: C06126
db: KEGG Compound

Lactosylceramide (d18:1/12:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0004866
xref: Reference/KEGG Compound C01290
xref: Reference/CAS 4682-48-8
xref: Reference/ChemSpider 16744880
xref: Reference/BioCyc CYTOLIPIN H
xref: Reference/PubChem-compound 20057304
chemical formula: C42H79NO13
molecular weight: 805.5551
structure: ChemicalStructure/PW C002240

Palmityl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 15667
xref: Reference/ChemSpider 14902
xref: Reference/HMDB HMDB0001338
xref: Reference/ChEBI CHEBI 15525
xref: Reference/KEGG Compound C00154
xref: Reference/CAS 1763-10-6
xref: Reference/BioCyc PALMITYL-COA
chemical formula: C37H66N7O17P3S
molecular weight: 1005.34485
structure: ChemicalStructure/PW C001031

ChemicalStructure/PW C000120
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CO)C(O)=O

Reference/HMDB HMDB0000122
type: UnificationXref
id: HMDB0000122
db: HMDB

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Compound/PW C000188 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphingosine 1-phosphate
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

ChemicalStructure/PW C003990
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCC(=O)OC[C@]([H])(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC

Reference/HMDB HMDB0001338
type: UnificationXref
id: HMDB0001338
db: HMDB

Sphingosine 1-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000277
xref: Reference/ChEBI CHEBI 37550
xref: Reference/KEGG Compound C06124
xref: Reference/PubChem-compound 5283560
xref: Reference/ChemSpider 4446673
xref: Reference/CAS 26993-30-6
chemical formula: C18H38NO5P
molecular weight: 379.24875
structure: ChemicalStructure/PW C000188

Reference/ChemSpider 4510275
type: UnificationXref
id: 4510275
db: ChemSpider

Sphinganine
type: SmallMoleculeReference
xref: Reference/CAS 764-22-7
xref: Reference/ChEBI CHEBI 16566
xref: Reference/HMDB HMDB0000269
xref: Reference/KEGG Compound C00836
xref: Reference/PubChem-compound 91486
xref: Reference/ChemSpider 82609
chemical formula: C18H39NO2
molecular weight: 301.29807
structure: ChemicalStructure/PW C000184

2.3.1.50
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000120 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001031 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001139 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytosol/Stoichiometry/1.0
right: 3-Dehydrosphinganine
right: Carbon dioxide
spontaneous: false
EC number: 2.3.1.50
left: Palmityl-CoA
left: L-Serine
name: L-Serine + Palmityl-CoA → 3-Dehydrosphinganine + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 17985
type: UnificationXref
id: CHEBI:17985
db: ChEBI

Reference/ChEBI CHEBI 17862
type: UnificationXref
id: CHEBI:17862
db: ChEBI

N-acetylneuraminyl-Galactosylceramide
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 27499
xref: Reference/HMDB HMDB0061363
chemical formula: C17H23NO3
molecular weight: 289.1678
structure: ChemicalStructure/PW C040684

Reference/KEGG Compound C00836
type: UnificationXref
id: C00836
db: KEGG Compound

Endoplasmic Reticulum
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005783

Endoplasmic Reticulum Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005789

Reference/ChemSpider 1085
type: UnificationXref
id: 1085
db: ChemSpider

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/UniProt B2RYC9
type: UnificationXref
id: B2RYC9
db: UniProt

Reference/TAXONOMY 10116
type: UnificationXref
id: 10116
db: TAXONOMY

ChemicalStructure/PW C002905
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC=O

Reference/ChEBI CHEBI 16893
type: UnificationXref
id: CHEBI:16893
db: ChEBI

Adenosine diphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Adenosine diphosphate

2-hydroxyacylsphingosine 1-beta-galactosyltransferase
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase

Reference/BioCyc UDP
type: UnificationXref
id: UDP
db: BioCyc

Reference/ChEBI CHEBI 17980
type: UnificationXref
id: CHEBI:17980
db: ChEBI

Reference/CAS 764-22-7
type: UnificationXref
id: 764-22-7
db: CAS

Reference/PubChem-compound 91486
type: UnificationXref
id: 91486
db: PubChem-compound

Reference/SMPDB SMP0000004
type: UnificationXref
id: SMP0000004
db: SMPDB

5-aminolevulinate synthase, nonspecific, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q6P782
organism: Rattus norvegicus

Compound/PW C000091 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucosylceramide
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17636
type: UnificationXref
id: CHEBI:17636
db: ChEBI

Reference/ChemSpider 82609
type: UnificationXref
id: 82609
db: ChemSpider

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Sphingosine-1-phosphate lyase 1
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Sphingosine-1-phosphate lyase 1

3.1.3.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000188 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000172 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Sphingosine 1-phosphate
right: Water
spontaneous: false
EC number: 3.1.3.4
left: Phosphate
left: Sphingosine
name: Phosphate + Sphingosine → Sphingosine 1-phosphate + Water
conversion direction: LEFT_TO_RIGHT

3.5.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000172 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002313 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Sphingosine
spontaneous: false
EC number: 3.5.1.23
left: Water
left: Ceramide (d18:1/18:0)
name: Ceramide (d18:1/18:0) + Water → Sphingosine
conversion direction: LEFT_TO_RIGHT

2.7.1.138
type: BiochemicalReaction
participant stoichiometry: Compound/PW C006709 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002313 Cell Membrane/Stoichiometry/1.0
right: Adenosine diphosphate
right: CerP(d18:1/18:0)
spontaneous: false
EC number: 2.7.1.138
left: Adenosine triphosphate
left: Ceramide (d18:1/18:0)
name: Adenosine triphosphate + Ceramide (d18:1/18:0) → Adenosine diphosphate + CerP(d18:1/18:0)
conversion direction: LEFT_TO_RIGHT

3.1.3.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C006709 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002313 Cell Membrane/Stoichiometry/1.0
right: Phosphate
right: Ceramide (d18:1/18:0)
spontaneous: false
EC number: 3.1.3.4
left: CerP(d18:1/18:0)
left: Water
name: CerP(d18:1/18:0) + Water → Ceramide (d18:1/18:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

3.1.3.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C006709 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002313 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: CerP(d18:1/18:0)
spontaneous: false
EC number: 3.1.3.-
left: Ceramide (d18:1/18:0)
name: Ceramide (d18:1/18:0) → CerP(d18:1/18:0)
conversion direction: LEFT_TO_RIGHT

2.7.8.27
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002313 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003990 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001040 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002928 Golgi apparatus/Stoichiometry/1.0
right: SM(d18:1/18:0)
right: Galactosylglycerol
spontaneous: false
EC number: 2.7.8.27
left: Ceramide (d18:1/18:0)
left: PC(15:0/18:2(9Z,12Z))
name: Ceramide (d18:1/18:0) + PC(15:0/18:2(9Z,12Z)) → Galactosylglycerol + SM(d18:1/18:0)
conversion direction: LEFT_TO_RIGHT

3.1.4.12
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001202 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002313 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001040 Golgi apparatus/Stoichiometry/1.0
right: Ceramide (d18:1/18:0)
right: Phosphorylcholine
spontaneous: false
EC number: 3.1.4.12
left: Water
left: SM(d18:1/18:0)
name: SM(d18:1/18:0) + Water → Ceramide (d18:1/18:0) + Phosphorylcholine
conversion direction: LEFT_TO_RIGHT

2.4.1.45
type: BiochemicalReaction
participant stoichiometry: Compound/PW C006716 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002313 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Galactosylceramide (d18:1/16:0)
spontaneous: false
EC number: 2.4.1.45
left: Ceramide (d18:1/18:0)
name: Ceramide (d18:1/18:0) → Galactosylceramide (d18:1/16:0)
conversion direction: LEFT_TO_RIGHT

3.2.1.46
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002313 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006716 Lysosome/Stoichiometry/1.0
right: Ceramide (d18:1/18:0)
spontaneous: false
EC number: 3.2.1.46
left: Galactosylceramide (d18:1/16:0)
name: Galactosylceramide (d18:1/16:0) → Ceramide (d18:1/18:0)
conversion direction: LEFT_TO_RIGHT

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

3.2.1.45
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002313 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000077 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000091 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Lysosome/Stoichiometry/1.0
right: D-Glucose
right: Ceramide (d18:1/18:0)
spontaneous: false
EC number: 3.2.1.45
left: Water
left: Glucosylceramide
name: Glucosylceramide + Water → Ceramide (d18:1/18:0) + D-Glucose
conversion direction: LEFT_TO_RIGHT

Reference/CAS 123-78-4
type: UnificationXref
id: 123-78-4
db: CAS

Reference/GENE ONTOLOGY GO 0005794
type: UnificationXref
id: GO:0005794
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 17600
type: UnificationXref
id: CHEBI:17600
db: ChEBI

Reference/BioCyc NH42SO4
type: UnificationXref
id: NH42SO4
db: BioCyc

Reference/ChemSpider 14902
type: UnificationXref
id: 14902
db: ChemSpider

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/BioCyc GALACTOSE
type: UnificationXref
id: GALACTOSE
db: BioCyc

Galactose-3-O-sulfotransferase 1
type: Protein
cellular location: Golgi apparatus
entity reference: Galactose-3-O-sulfotransferase 1

Reference/ChemSpider 5589
type: UnificationXref
id: 5589
db: ChemSpider

2.4.1.80
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000201 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000193 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000091 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002313 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Uridine 5'-diphosphate
right: Glucosylceramide
spontaneous: false
EC number: 2.4.1.80
left: Ceramide (d18:1/18:0)
left: Uridine diphosphate glucose
name: Ceramide (d18:1/18:0) + Uridine diphosphate glucose → Glucosylceramide + Uridine 5'-diphosphate
conversion direction: LEFT_TO_RIGHT

3.2.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000091 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002240 Cytosol/Stoichiometry/1.0
right: Glucosylceramide
spontaneous: false
EC number: 3.2.1.23
left: Lactosylceramide (d18:1/12:0)
name: Lactosylceramide (d18:1/12:0) → Glucosylceramide
conversion direction: LEFT_TO_RIGHT

Reaction147812
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000193 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000091 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000201 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002240 Golgi apparatus/Stoichiometry/1.0
right: Glucosylceramide
right: Uridine diphosphate glucose
spontaneous: false
left: Uridine 5'-diphosphate
left: Lactosylceramide (d18:1/12:0)
name: Lactosylceramide (d18:1/12:0) + Uridine 5'-diphosphate ← Glucosylceramide + Uridine diphosphate glucose
conversion direction: RIGHT_TO_LEFT

Reference/UniProt Q5PQK7
type: UnificationXref
id: Q5PQK7
db: UniProt

2.8.2.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C006716 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000017 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000886 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000043 Golgi apparatus/Stoichiometry/1.0
right: Adenosine 3',5'-diphosphate
right: 3-O-Sulfogalactosylceramide (d18:1/24:0)
spontaneous: false
EC number: 2.8.2.11
left: Galactosylceramide (d18:1/16:0)
left: Phosphoadenosine phosphosulfate
name: Galactosylceramide (d18:1/16:0) + Phosphoadenosine phosphosulfate → 3-O-Sulfogalactosylceramide (d18:1/24:0) + Adenosine 3',5'-diphosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

3.1.6.8
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000017 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001118 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006716 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Lysosome/Stoichiometry/1.0
right: Sulfate
right: Galactosylceramide (d18:1/16:0)
spontaneous: false
EC number: 3.1.6.8
left: Water
left: 3-O-Sulfogalactosylceramide (d18:1/24:0)
name: 3-O-Sulfogalactosylceramide (d18:1/24:0) + Water → Galactosylceramide (d18:1/16:0) + Sulfate
conversion direction: LEFT_TO_RIGHT

3.2.1.22
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000093 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006716 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002212 Lysosome/Stoichiometry/1.0
right: Galabiosylceramide (d18:1/22:0)
spontaneous: false
EC number: 3.2.1.22
left: D-Galactose
left: Galactosylceramide (d18:1/16:0)
name: D-Galactose + Galactosylceramide (d18:1/16:0) ← Galabiosylceramide (d18:1/22:0)
conversion direction: RIGHT_TO_LEFT

2.8.2.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002212 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000886 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/Generic35 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000043 Golgi apparatus/Stoichiometry/1.0
right: Adenosine 3',5'-diphosphate
right: Galabiosylceramide-sulfate
spontaneous: false
EC number: 2.8.2.11
left: Galabiosylceramide (d18:1/22:0)
left: Phosphoadenosine phosphosulfate
name: Galabiosylceramide (d18:1/22:0) + Phosphoadenosine phosphosulfate → Adenosine 3',5'-diphosphate + Galabiosylceramide-sulfate
conversion direction: LEFT_TO_RIGHT

D-Galactose
type: SmallMoleculeReference
xref: Reference/BioCyc GALACTOSE
xref: Reference/PubChem-compound 439357
xref: Reference/CAS 59-23-4
xref: Reference/ChEBI CHEBI 28061
xref: Reference/ChemSpider 388480
xref: Reference/KEGG Compound C00984
xref: Reference/HMDB HMDB0000143
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000093

3.2.1.18
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040684 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006716 Endoplasmic Reticulum/Stoichiometry/1.0
right: N-acetylneuraminyl-Galactosylceramide
spontaneous: false
EC number: 3.2.1.18
left: Galactosylceramide (d18:1/16:0)
name: Galactosylceramide (d18:1/16:0) → N-acetylneuraminyl-Galactosylceramide
conversion direction: LEFT_TO_RIGHT

3.5.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002905 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000184 Cytosol/Stoichiometry/1.0
right: Sphinganine
spontaneous: false
EC number: 3.5.1.-
left: Dihydroceramide
name: Dihydroceramide → Sphinganine
conversion direction: LEFT_TO_RIGHT

Glucosylceramide
type: SmallMoleculeReference
xref: Reference/BioCyc GLUCOSYL CERAMIDE
xref: Reference/KEGG Compound C01190
xref: Reference/PubChem-compound 53477677
xref: Reference/CAS 85305-87-9
xref: Reference/ChemSpider 24765741
xref: Reference/HMDB HMDB0000140
chemical formula: C48H93NO8
molecular weight: 811.6901
structure: ChemicalStructure/PW C000091

Reference/BioCyc GALACTOSYLCERAMIDE-SULFATE
type: UnificationXref
id: GALACTOSYLCERAMIDE-SULFATE
db: BioCyc

Reference/GENE ONTOLOGY GO 0005789
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

Reference/GENE ONTOLOGY GO 0005783
type: UnificationXref
id: GO:0005783
db: GENE ONTOLOGY

Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

O-Phosphoethanolamine
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: O-Phosphoethanolamine

Water
type: SmallMolecule
cellular location: Lysosome
entity reference: Water

Reference/CAS 85187-10-6
type: UnificationXref
id: 85187-10-6
db: CAS

Reference/ChemSpider 4446701
type: UnificationXref
id: 4446701
db: ChemSpider

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Galabiosylceramide-sulfate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C06126

Reference/KEGG Compound C00984
type: UnificationXref
id: C00984
db: KEGG Compound

Dehydrogenase/reductase SDR family member 7B
type: Protein
cellular location: Cytosol
entity reference: Dehydrogenase/reductase SDR family member 7B

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Compound/PW C002240 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lactosylceramide (d18:1/12:0)
stoichiometric coefficient: 1.0

Reference/UniProt Q32KJ9
type: UnificationXref
id: Q32KJ9
db: UniProt

Reference/ChemSpider 16744853
type: UnificationXref
id: 16744853
db: ChemSpider

Compound/PW C000091 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucosylceramide
stoichiometric coefficient: 1.0

Sphinganine 1-phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644260
xref: Reference/ChemSpider 559277
xref: Reference/KEGG Compound C01120
xref: Reference/HMDB HMDB0001383
xref: Reference/CAS 19794-97-9
xref: Reference/ChEBI CHEBI 16893
xref: Reference/BioCyc CPD-649
chemical formula: C18H40NO5P
molecular weight: 381.2644
structure: ChemicalStructure/PW C001070

Palmitaldehyde
type: SmallMoleculeReference
xref: Reference/PubChem-compound 984
xref: Reference/ChEBI CHEBI 17600
xref: Reference/KEGG Compound C00517
xref: Reference/ChemSpider 959
xref: Reference/HMDB HMDB0001551
xref: Reference/CAS 629-80-1
xref: Reference/BioCyc PALMITALDEHYDE
chemical formula: C16H32O
molecular weight: 240.24532
structure: ChemicalStructure/PW C001193

Palmitaldehyde
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Palmitaldehyde

Reference/KEGG Compound C02934
type: UnificationXref
id: C02934
db: KEGG Compound

Reference/KEGG Compound C00517
type: UnificationXref
id: C00517
db: KEGG Compound

Reference/ChemSpider 24765744
type: UnificationXref
id: 24765744
db: ChemSpider

Reference/ChemSpider 24765741
type: UnificationXref
id: 24765741
db: ChemSpider

ChemicalStructure/PW C000886
type: ChemicalStructure
structure format: SMILES

Golgi apparatus
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005794

Reference/CAS 26993-30-6
type: UnificationXref
id: 26993-30-6
db: CAS

Reference/BioCyc PAPS
type: UnificationXref
id: PAPS
db: BioCyc

Compound/PW C000201 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

Compound/PW C000149 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: O-Phosphoethanolamine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 439357
type: UnificationXref
id: 439357
db: PubChem-compound

Compound/PW C001040 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: SM(d18:1/18:0)
stoichiometric coefficient: 1.0

L-Serine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Serine

Compound/PW C002313 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ceramide (d18:1/18:0)
stoichiometric coefficient: 1.0

Cell Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005886

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Galactosylceramide (d18:1/16:0)
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Galactosylceramide (d18:1/16:0)

3-Dehydrosphinganine
type: SmallMolecule
cellular location: Cytosol
entity reference: 3-Dehydrosphinganine

Reference/CAS 56-45-1
type: UnificationXref
id: 56-45-1
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

CerP(d18:1/18:0)
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: CerP(d18:1/18:0)

Reference/UniProt Q5EZ72
type: UnificationXref
id: Q5EZ72
db: UniProt

Reference/ChEBI CHEBI 17553
type: UnificationXref
id: CHEBI:17553
db: ChEBI

Reference/PubChem-compound 20057304
type: UnificationXref
id: 20057304
db: PubChem-compound

Compound/PW C001420 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Ceramide (d18:1/18:0)
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Ceramide (d18:1/18:0)

Compound/PW C000184 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphinganine
stoichiometric coefficient: 1.0

Reference/ChemSpider 24766615
type: UnificationXref
id: 24766615
db: ChemSpider

Reference/PubChem-compound 5793
type: UnificationXref
id: 5793
db: PubChem-compound

N-acetylneuraminyl-Galactosylceramide
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: N-acetylneuraminyl-Galactosylceramide

ChemicalStructure/PW C002928
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 53480652
type: UnificationXref
id: 53480652
db: PubChem-compound

Compound/PW C003990 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: PC(15:0/18:2(9Z,12Z))
stoichiometric coefficient: 1.0

Unknown
type: ProteinReference
organism: Rattus norvegicus

Reference/PubChem-compound 6451121
type: UnificationXref
id: 6451121
db: PubChem-compound

Compound/PW C006716 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactosylceramide (d18:1/16:0)
stoichiometric coefficient: 1.0

Reference/UniProt Q6P782
type: UnificationXref
id: Q6P782
db: UniProt

Reference/ChemSpider 16744880
type: UnificationXref
id: 16744880
db: ChemSpider

Compound/PW C000091 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucosylceramide
stoichiometric coefficient: 1.0

Reference/PubChem-compound 15667
type: UnificationXref
id: 15667
db: PubChem-compound

Galabiosylceramide (d18:1/22:0)
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Galabiosylceramide (d18:1/22:0)

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/ChEBI CHEBI 16566
type: UnificationXref
id: CHEBI:16566
db: ChEBI

Reference/ChEBI CHEBI 60361
type: UnificationXref
id: CHEBI:60361
db: ChEBI

Reference/ChEBI CHEBI 17659
type: UnificationXref
id: CHEBI:17659
db: ChEBI

Compound/PW C002212 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galabiosylceramide (d18:1/22:0)
stoichiometric coefficient: 1.0

Compound/PW C006709 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: CerP(d18:1/18:0)
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Compound/PW C001070 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sphinganine 1-phosphate
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Adenosine diphosphate

Dihydroceramide
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Dihydroceramide

Reference/CAS 85305-87-9
type: UnificationXref
id: 85305-87-9
db: CAS

Adenosine 3',5'-diphosphate
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Adenosine 3',5'-diphosphate

Glucosylceramide
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Glucosylceramide

Reference/CAS 77538-38-6
type: UnificationXref
id: 77538-38-6
db: CAS