Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
L-Malic acid + NAD ↔ Hydrogen Ion + NADH + Oxalacetic acid
Transfer of Acetyl Groups into Mitochondria
Adenosine triphosphate + Hydrogen carbonate + Pyruvic acid → Adenosine diphosphate + Oxalacetic acid + Phosphate
Acetyl-CoA + Oxalacetic acid + Water → Citric acid + Coenzyme A
L-Malic acid (→) Transport: Rattus norvegicus, Cell, Cytosol to Rattus norvegicus, Cell, Mitochondrion
Citric acid (←) Transport: Rattus norvegicus, Cell, Cytosol to Rattus norvegicus, Cell, Mitochondrial Matrix
Mitochondrial 2-oxoglutarate/malate carrier protein
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
L-Malic acid + NADP → Carbon dioxide + Hydrogen + NADPH + Pyruvic acid
Hydrogen + NADPH + Oxalacetic acid → L-Malic acid + NAD
Adenosine triphosphate + Citric acid + Coenzyme A → Acetyl-CoA + Adenosine diphosphate + Oxalacetic acid
Pyruvic acid (→) Transport: Rattus norvegicus, Cell, Cytosol to Rattus norvegicus, Cell, Mitochondrial Matrix