Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/KEGG Compound C00798
type: UnificationXref
id: C00798
db: KEGG Compound

Propionylcarnitine
type: SmallMolecule
cellular location: Peroxisome
entity reference: Propionylcarnitine

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/KEGG Compound C00318
type: UnificationXref
id: C00318
db: KEGG Compound

4,8-Dimethylnonanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: 4,8-Dimethylnonanoyl-CoA
name: SubPathwayOutput

Reference/ChEBI CHEBI 49189
type: UnificationXref
id: CHEBI:49189
db: ChEBI

Transport10044
type: Transport
participant stoichiometry: Compound/PW C001049 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001049 Peroxisome/Stoichiometry/1.0
right: Phytanoyl-CoA
spontaneous: false
left: Phytanoyl-CoA
name: Phytanoyl-CoA (→) Transport: Rattus norvegicus, Cell, Peroxisome to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Aldehyde dehydrogenase, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Aldehyde dehydrogenase, mitochondrial

Pristanal
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Pristanal

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Compound/PW C000414 Peroxisome Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 441253
type: UnificationXref
id: 441253
db: PubChem-compound

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Phytanoyl-CoA dioxygenase, peroxisomal
type: Protein
cellular location: Peroxisome
entity reference: Phytanoyl-CoA dioxygenase, peroxisomal

Compound/PW C001381 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Compound/PW C007198 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4,8-Dimethylnonanoyl-CoA
stoichiometric coefficient: 1.0

Acetyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Acetyl-CoA
name: SubPathwayOutput

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

Reference/HMDB HMDB0002057
type: UnificationXref
id: HMDB0002057
db: HMDB

Phytanoyl-CoA dioxygenase, peroxisomal
type: ProteinReference
xref: Reference/UniProt Q9QY64
organism: Rattus norvegicus

Oxidation of Branched-Chain Fatty Acids
type: Pathway
pathway order: PathwaySubPathway/108671
pathway order: PathwaySubPathway/108672
pathway order: PathwaySubPathway/108673
pathway order: PathwayEnzymeReaction/2115089
pathway order: PathwaySubPathway/108670
pathway order: PathwayTransport/2115101
pathway order: PathwayTransport/2115100
pathway order: PathwayTransport/2115103
pathway order: PathwayTransport/2115102
pathway order: PathwayEnzymeReaction/2115091
pathway order: PathwayTransport/2115097
pathway order: PathwayEnzymeReaction/2115090
pathway order: PathwayTransport/2115096
pathway order: PathwayTransport/2115099
pathway order: PathwayTransport/2115098
pathway order: PathwayEnzymeReaction/2115095
pathway order: PathwayEnzymeReaction/2115094
pathway order: PathwayEnzymeReaction/2115093
pathway order: PathwayEnzymeReaction/2115092
pathway order: PathwayEnzymeReaction/2115088
pathway order: PathwayEnzymeReaction/2115087
pathway order: PathwayEnzymeReaction/2115086
pathway order: PathwayEnzymeReaction/2115085
pathway component: 1.14.11.18
pathway component: ReactionCatalysis138248
pathway component: ReactionCatalysis138247
pathway component: ReactionCatalysis138244
pathway component: ReactionCatalysis138246
pathway component: Transport1177
pathway component: ReactionCatalysis138245
pathway component: Transport1176
pathway component: 6.2.1.3
pathway component: 1.2.1.3
pathway component: Beta Oxidation
pathway component: Transport8052
pathway component: Transport10044
pathway component: Transport8054
pathway component: Transport8055
pathway component: 4.1.-.-
pathway component: Transport8050
pathway component: TransportCatalysis992
pathway component: Transport8051
pathway component: TransportCatalysis991
pathway component: ReactionCatalysis137501
pathway component: ReactionCatalysis137502
pathway component: 2.3.1.7
pathway component: Reaction147981
pathway component: TransportCatalysis1256
pathway component: ReactionCatalysis137504
pathway component: TransportCatalysis1074
pathway component: TransportCatalysis1073
pathway component: TransportCatalysis1076
pathway component: TransportCatalysis1075
pathway component: TransportCatalysis1072
xref: Reference/SMPDB SMP0087348
xref: Reference/PathWhiz PW088367
organism: Rattus norvegicus

Compound/PW C001034 Peroxisome Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00100
type: UnificationXref
id: C00100
db: KEGG Compound

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 439164
type: UnificationXref
id: 439164
db: PubChem-compound

Rattus norvegicus
type: BioSource
xref: Reference/TAXONOMY 10116

L-Acetylcarnitine
type: SmallMolecule
cellular location: Mitochondrion
entity reference: L-Acetylcarnitine

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

2-hydroxyacyl-CoA lyase 1
type: ProteinReference
xref: Reference/UniProt Q8CHM7
organism: Rattus norvegicus

Propionyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 317-66-8
xref: Reference/PubChem-compound 439164
xref: Reference/KEGG Compound C00100
xref: Reference/ChEBI CHEBI 15539
xref: Reference/BioCyc PROPIONYL-COA
xref: Reference/ChemSpider 388310
xref: Reference/HMDB HMDB0001275
chemical formula: C24H40N7O17P3S
molecular weight: 823.1414
structure: ChemicalStructure/PW C000988

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Formyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Formyl-CoA

Protein/14622/Stoichiometry/1.0
type: Stoichiometry
physical entity: Peroxisomal membrane protein PEX14
stoichiometric coefficient: 1.0

Reference/ChemSpider 388310
type: UnificationXref
id: 388310
db: ChemSpider

Reference/BioCyc SUC
type: UnificationXref
id: SUC
db: BioCyc

Transport8052
type: Transport
participant stoichiometry: Compound/PW C002659 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002659 Peroxisome/Stoichiometry/1.0
right: 4,8 Dimethylnonanoyl carnitine
spontaneous: false
left: 4,8 Dimethylnonanoyl carnitine
name: 4,8 Dimethylnonanoyl carnitine (→) Transport: Rattus norvegicus, Cell, Peroxisome to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 51340
type: UnificationXref
id: CHEBI:51340
db: ChEBI

Transport8054
type: Transport
participant stoichiometry: Compound/PW C000658 Mitochondrial Intermembrane Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000658 Mitochondrial Matrix/Stoichiometry/1.0
right: Propionylcarnitine
spontaneous: false
left: Propionylcarnitine
name: Propionylcarnitine (→) Transport: Rattus norvegicus, Cell, Mitochondrial Intermembrane Space to Rattus norvegicus, Cell, Mitochondrial Matrix
conversion direction: LEFT_TO_RIGHT

Transport8055
type: Transport
participant stoichiometry: Compound/PW C002659 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002659 Mitochondrial Intermembrane Space/Stoichiometry/1.0
right: 4,8 Dimethylnonanoyl carnitine
spontaneous: false
left: 4,8 Dimethylnonanoyl carnitine
name: 4,8 Dimethylnonanoyl carnitine (→) Transport: Rattus norvegicus, Cell, Mitochondrial Intermembrane Space to Rattus norvegicus, Cell, Mitochondrial Matrix
conversion direction: LEFT_TO_RIGHT

Propionyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Propionyl-CoA

Transport8050
type: Transport
participant stoichiometry: Compound/PW C001381 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001381 Peroxisome/Stoichiometry/1.0
right: Pristanoyl-CoA
spontaneous: false
left: Pristanoyl-CoA
name: Pristanoyl-CoA (→) Transport: Rattus norvegicus, Cell, Cytoplasm to Rattus norvegicus, Cell, Peroxisome
conversion direction: LEFT_TO_RIGHT

Compound/PW C001049 Peroxisome Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phytanoyl-CoA
stoichiometric coefficient: 1.0

Transport8051
type: Transport
participant stoichiometry: Compound/PW C000658 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000658 Cytosol/Stoichiometry/1.0
right: Propionylcarnitine
spontaneous: false
left: Propionylcarnitine
name: Propionylcarnitine (→) Transport: Rattus norvegicus, Cell, Peroxisome to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

2-Hydroxyphytanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15475
xref: Reference/KEGG Compound C07343
xref: Reference/BioCyc 2-HYDROXYPHYTANOYL-COA
xref: Reference/PubChem-compound 441263
xref: Reference/ChemSpider 390032
xref: Reference/CAS 172787-73-4
xref: Reference/HMDB HMDB0001295
chemical formula: C41H74N7O18P3S
molecular weight: 1077.4023
structure: ChemicalStructure/PW C000999

Reference/ChemSpider 388444
type: UnificationXref
id: 388444
db: ChemSpider

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Compound/PW C000129 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

Pristanic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 51340
xref: Reference/HMDB HMDB0000795
xref: Reference/CAS 1189-37-3
xref: Reference/ChemSpider 110458
xref: Reference/PubChem-compound 123929
chemical formula: C19H38O2
molecular weight: 298.28717
structure: ChemicalStructure/PW C000635

Reference/BioCyc PROPIONYL-COA
type: UnificationXref
id: PROPIONYL-COA
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Phytanic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 26840
xref: Reference/CAS 14721-66-5
xref: Reference/KEGG Compound C01607
xref: Reference/ChemSpider 25001
xref: Reference/HMDB HMDB0000801
xref: Reference/ChEBI CHEBI 16285
chemical formula: C20H40O2
molecular weight: 312.30283
structure: ChemicalStructure/PW C000639

Pristanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Pristanoyl-CoA

Reference/CAS 13131-49-2
type: UnificationXref
id: 13131-49-2
db: CAS

Adenosine diphosphate
type: SmallMolecule
cellular location: Peroxisome Membrane
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0006202
type: UnificationXref
id: HMDB0006202
db: HMDB

Reference/ChemSpider 13628282
type: UnificationXref
id: 13628282
db: ChemSpider

Reference/PubChem-compound 441263
type: UnificationXref
id: 441263
db: PubChem-compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/ChEBI CHEBI 73024
type: UnificationXref
id: CHEBI:73024
db: ChEBI

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/PubChem-compound 1
type: UnificationXref
id: 1
db: PubChem-compound

Reference/CAS 204120-61-6
type: UnificationXref
id: 204120-61-6
db: CAS

Reference/PubChem-compound 26840
type: UnificationXref
id: 26840
db: PubChem-compound

Compound/PW C002659 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4,8 Dimethylnonanoyl carnitine
stoichiometric coefficient: 1.0

Phytanic acid
type: SmallMolecule
cellular location: Peroxisome Membrane
entity reference: Phytanic acid

Reference/BioCyc CARNITINE
type: UnificationXref
id: CARNITINE
db: BioCyc

Reference/BioCyc FORMYL-COA
type: UnificationXref
id: FORMYL-COA
db: BioCyc

Mitochondrial 2-oxodicarboxylate carrier
type: Protein
entity reference: Mitochondrial 2-oxodicarboxylate carrier

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Peroxisomal membrane protein PEX14
type: Protein
entity reference: Peroxisomal membrane protein PEX14

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/ChEBI CHEBI 16285
type: UnificationXref
id: CHEBI:16285
db: ChEBI

Reference/UniProt F1LN46
type: UnificationXref
id: F1LN46
db: UniProt

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/CAS 317-66-8
type: UnificationXref
id: 317-66-8
db: CAS

Compound/PW C000658 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionylcarnitine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C02571
type: UnificationXref
id: C02571
db: KEGG Compound

Reference/UniProt Q99JD3
type: UnificationXref
id: Q99JD3
db: UniProt

Propionylcarnitine
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Propionylcarnitine

Phytanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Phytanoyl-CoA

Propionylcarnitine
type: SmallMolecule
cellular location: Cytosol
entity reference: Propionylcarnitine

Protein/15360 Mitochondrion/Stoichiometry/4.0
type: Stoichiometry
physical entity: Aldehyde dehydrogenase, mitochondrial
stoichiometric coefficient: 4.0

4,8-Dimethylnonanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 4,8-Dimethylnonanoyl-CoA
name: SubPathwayInput

Transport1177
type: Transport
participant stoichiometry: Compound/PW C000129 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000129 Cytosol/Stoichiometry/1.0
right: L-Acetylcarnitine
spontaneous: false
left: L-Acetylcarnitine
name: L-Acetylcarnitine (→) Transport: Rattus norvegicus, Cell, Cytosol to Rattus norvegicus, Cell, Mitochondrial Matrix
conversion direction: LEFT_TO_RIGHT

Transport1176
type: Transport
participant stoichiometry: Compound/PW C000129 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000129 Cytosol/Stoichiometry/1.0
right: L-Acetylcarnitine
spontaneous: false
left: L-Acetylcarnitine
name: L-Acetylcarnitine (→) Transport: Rattus norvegicus, Cell, Peroxisome to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Propionylcarnitine
type: SmallMolecule
cellular location: Mitochondrial Intermembrane Space
entity reference: Propionylcarnitine

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Reference/HMDB HMDB0000254
type: UnificationXref
id: HMDB0000254
db: HMDB

Peroxisome
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005777

ChemicalStructure/PW C000174
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(O)=O

Reference/CAS 105373-75-9
type: UnificationXref
id: 105373-75-9
db: CAS

Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Formyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 13131-49-2
xref: Reference/ChEBI CHEBI 15522
xref: Reference/ChemSpider 388444
xref: Reference/KEGG Compound C00798
xref: Reference/PubChem-compound 439313
xref: Reference/BioCyc FORMYL-COA
xref: Reference/HMDB HMDB0003419
chemical formula: C22H36N7O17P3S
molecular weight: 795.1101
structure: ChemicalStructure/PW C001883

Reference/CAS 172787-73-4
type: UnificationXref
id: 172787-73-4
db: CAS

ChemicalStructure/PW C001381
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

TransportCatalysis992
type: Catalysis
controller: Mitochondrial 2-oxodicarboxylate carrier
controlled: Transport1177
control type: ACTIVATION

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

TransportCatalysis991
type: Catalysis
controller: Peroxisomal membrane protein
controlled: Transport1176
control type: ACTIVATION

ReactionCatalysis137501
type: Catalysis
controller: Long-chain-fatty-acid--CoA ligase ACSBG2
controlled: 6.2.1.3
control type: ACTIVATION

ReactionCatalysis137502
type: Catalysis
controller: 2-hydroxyacyl-CoA lyase 1
controlled: 4.1.-.-
control type: ACTIVATION

Compound/PW C000044 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Carnitine
stoichiometric coefficient: 1.0

2-hydroxyacyl-CoA lyase 1
type: Complex
component stoichiometry: Protein/15925 Peroxisome/Stoichiometry/4.0
cellular location: Peroxisome
component: 2-hydroxyacyl-CoA lyase 1

Reference/KEGG Compound C00042
type: UnificationXref
id: C00042
db: KEGG Compound

Unknown
type: Protein
entity reference: Unknown

L-Acetylcarnitine
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: L-Acetylcarnitine

ReactionCatalysis137504
type: Catalysis
controller: Phytanoyl-CoA dioxygenase, peroxisomal
controlled: 1.14.11.18
control type: ACTIVATION

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc 2-HYDROXYPHYTANOYL-COA
type: UnificationXref
id: 2-HYDROXYPHYTANOYL-COA
db: BioCyc

Reference/ChemSpider 110458
type: UnificationXref
id: 110458
db: ChemSpider

Reference/HMDB HMDB0001359
type: UnificationXref
id: HMDB0001359
db: HMDB

Compound/PW C001883 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Formyl-CoA
stoichiometric coefficient: 1.0

4,8-Dimethylnonanoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 204120-61-6
xref: Reference/HMDB HMDB0011604
xref: Reference/PubChem-compound 53481003
chemical formula: C32H56N7O17P3S
molecular weight: 935.2666
structure: ChemicalStructure/PW C007198

Reference/PubChem-compound 123929
type: UnificationXref
id: 123929
db: PubChem-compound

Compound/PW C000658 Mitochondrial Intermembrane Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionylcarnitine
stoichiometric coefficient: 1.0

L-Carnitine
type: SmallMolecule
cellular location: Peroxisome
entity reference: L-Carnitine

Compound/PW C000134 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 25001
type: UnificationXref
id: 25001
db: ChemSpider

4,8 Dimethylnonanoyl carnitine
type: SmallMolecule
cellular location: Cytosol
entity reference: 4,8 Dimethylnonanoyl carnitine

Propionyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Propionyl-CoA
name: SubPathwayOutput

Reference/HMDB HMDB0003419
type: UnificationXref
id: HMDB0003419
db: HMDB

Compound/PW C002659 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4,8 Dimethylnonanoyl carnitine
stoichiometric coefficient: 1.0

Pristanal
type: SmallMolecule
cellular location: Peroxisome
entity reference: Pristanal

Compound/PW C001381 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanoyl-CoA
stoichiometric coefficient: 1.0

Propionylcarnitine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 107738
xref: Reference/ChEBI CHEBI 28867
xref: Reference/HMDB HMDB0000824
xref: Reference/KEGG Compound C03017
xref: Reference/ChemSpider 96904
xref: Reference/CAS 17298-37-2
chemical formula: C10H19NO4
molecular weight: 217.13141
structure: ChemicalStructure/PW C000658

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/UniProt Q9QY64
type: UnificationXref
id: Q9QY64
db: UniProt

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

ChemicalStructure/PW C000044
type: ChemicalStructure
structure format: SMILES
structure data: C[N+](C)(C)C[C@H](O)CC([O-])=O

Pristanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome Membrane
entity reference: Pristanoyl-CoA

Compound/PW C000129 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

Pyrophosphate
type: SmallMolecule
cellular location: Peroxisome Membrane
entity reference: Pyrophosphate

TransportCatalysis1074
type: Catalysis
controller: Peroxisomal membrane protein
controlled: Transport8052
control type: ACTIVATION

TransportCatalysis1073
type: Catalysis
controller: Peroxisomal membrane protein
controlled: Transport8051
control type: ACTIVATION

TransportCatalysis1076
type: Catalysis
controller: Mitochondrial 2-oxodicarboxylate carrier
controlled: Transport8055
control type: ACTIVATION

TransportCatalysis1075
type: Catalysis
controller: Mitochondrial 2-oxodicarboxylate carrier
controlled: Transport8054
control type: ACTIVATION

Compound/PW C001309 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanal
stoichiometric coefficient: 1.0

TransportCatalysis1072
type: Catalysis
controller: Peroxisomal membrane protein
controlled: Transport8050
control type: ACTIVATION

Reference/ChemSpider 388712
type: UnificationXref
id: 388712
db: ChemSpider

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Compound/PW C001309 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanal
stoichiometric coefficient: 1.0

Reference/BioCyc (-)o-acetylcarnitine
type: UnificationXref
id: (-)o-acetylcarnitine
db: BioCyc

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Compound/PW C001381 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanoyl-CoA
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Coenzyme A
type: SmallMolecule
cellular location: Peroxisome Membrane
entity reference: Coenzyme A

Compound/PW C007198 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4,8-Dimethylnonanoyl-CoA
stoichiometric coefficient: 1.0

TransportCatalysis1256
type: Catalysis
controller: ATP-binding cassette sub-family D member 2
controlled: Transport10044
control type: ACTIVATION

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

4,8 Dimethylnonanoyl carnitine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 53477801
xref: Reference/HMDB HMDB0006202
xref: Reference/ChemSpider 21233922
xref: Reference/ChEBI CHEBI 63874
chemical formula: C18H35NO4
molecular weight: 329.25662
structure: ChemicalStructure/PW C002659

Reference/UniProt Q9QY44
type: UnificationXref
id: Q9QY44
db: UniProt

Reference/HMDB HMDB0000062
type: UnificationXref
id: HMDB0000062
db: HMDB

SubPathwayInteraction108670
type: Interaction
name: SubPathwayReaction
name: SubPathway108670Reaction
participant: Propionyl-CoA
participant: Pristanoyl-CoA

SubPathwayInteraction108671
type: Interaction
name: SubPathway108671Reaction
name: SubPathwayReaction
participant: Acetyl-CoA
participant: Pristanoyl-CoA

SubPathwayInteraction108672
type: Interaction
name: SubPathway108672Reaction
name: SubPathwayReaction
participant: Pristanoyl-CoA
participant: 4,8-Dimethylnonanoyl-CoA

Reference/HMDB HMDB0001275
type: UnificationXref
id: HMDB0001275
db: HMDB

Compound/PW C002659 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4,8 Dimethylnonanoyl carnitine
stoichiometric coefficient: 1.0

SubPathwayInteraction108673
type: Interaction
name: SubPathwayReaction
name: SubPathway108673Reaction
participant: 4,8-Dimethylnonanoyl-CoA
participant: Acetyl-CoA

Compound/PW C000658 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionylcarnitine
stoichiometric coefficient: 1.0

Carnitine O-palmitoyltransferase 1, brain isoform
type: Protein
cellular location: Mitochondrion
entity reference: Carnitine O-palmitoyltransferase 1, brain isoform

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/PubChem-compound 53477801
type: UnificationXref
id: 53477801
db: PubChem-compound

Compound/PW C000988 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

ChemicalStructure/PW C001049
type: ChemicalStructure
structure format: SMILES

Propionylcarnitine
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Propionylcarnitine

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

Phytanoyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Phytanoyl-CoA

Reference/KEGG Compound C03017
type: UnificationXref
id: C03017
db: KEGG Compound

Pristanal
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 49189
xref: Reference/ChemSpider 13628282
xref: Reference/CAS 105373-75-9
xref: Reference/PubChem-compound 14671060
xref: Reference/HMDB HMDB0001958
chemical formula: C19H38O
molecular weight: 282.29227
structure: ChemicalStructure/PW C001309

Reference/HMDB HMDB0001295
type: UnificationXref
id: HMDB0001295
db: HMDB

4,8 Dimethylnonanoyl carnitine
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 4,8 Dimethylnonanoyl carnitine

Beta Oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108672
pathway component: SubPathwayInteraction108672
name: SubPathway

Compound/PW C001316 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Beta Oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108673
pathway component: SubPathwayInteraction108673
name: SubPathway

Reference/KEGG Compound C02060
type: UnificationXref
id: C02060
db: KEGG Compound

Compound/PW C000988 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionyl-CoA
stoichiometric coefficient: 1.0

Reference/PubChem-compound 53481003
type: UnificationXref
id: 53481003
db: PubChem-compound

Compound/PW C000658 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionylcarnitine
stoichiometric coefficient: 1.0

Pristanoyl-CoA
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pristanoyl-CoA

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Acetyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Acetyl-CoA
name: SubPathwayOutput

Protein/7758/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

L-Acetylcarnitine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Acetylcarnitine

ChemicalStructure/PW C001309
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)CCCC(C)CCCC(C)CCCC(C)C=O

Peroxisome Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005778

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Carbon dioxide
type: SmallMolecule
cellular location: Peroxisome
entity reference: Carbon dioxide

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

L-Carnitine
type: SmallMoleculeReference
xref: Reference/BioCyc CARNITINE
xref: Reference/ChEBI CHEBI 16347
xref: Reference/PubChem-compound 10917
xref: Reference/CAS 541-15-1
xref: Reference/KEGG Compound C00318
xref: Reference/HMDB HMDB0000062
xref: Reference/ChemSpider 10455
chemical formula: C7H15NO3
molecular weight: 161.1052
structure: ChemicalStructure/PW C000044

L-Acetylcarnitine
type: SmallMoleculeReference
xref: Reference/CAS 3040-38-8
xref: Reference/PubChem-compound 1
xref: Reference/ChemSpider 21243783
xref: Reference/HMDB HMDB0000201
xref: Reference/KEGG Compound C02571
xref: Reference/BioCyc (-)o-acetylcarnitine
xref: Reference/ChEBI CHEBI 73024
chemical formula: C9H17NO4
molecular weight: 203.11575
structure: ChemicalStructure/PW C000129

Reference/PathWhiz PW088367
type: UnificationXref
id: PW088367
db: PathWhiz

Reference/CAS 17298-37-2
type: UnificationXref
id: 17298-37-2
db: CAS

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/HMDB HMDB0000795
type: UnificationXref
id: HMDB0000795
db: HMDB

ChemicalStructure/PW C001883
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Compound/PW C000170 Peroxisome Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Compound/PW C000129 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

Aldehyde dehydrogenase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q91ZD7
organism: Rattus norvegicus

Reference/CAS 3040-38-8
type: UnificationXref
id: 3040-38-8
db: CAS

Reference/HMDB HMDB0000201
type: UnificationXref
id: HMDB0000201
db: HMDB

Reference/CAS 1189-37-3
type: UnificationXref
id: 1189-37-3
db: CAS

Reference/BioCyc 3-OXOPRISTANOYL-COA
type: UnificationXref
id: 3-OXOPRISTANOYL-COA
db: BioCyc

Compound/PW C002659 Mitochondrial Intermembrane Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4,8 Dimethylnonanoyl carnitine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C007198
type: ChemicalStructure
structure format: SMILES

Mitochondrion
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005739

1.14.11.18
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000134 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000999 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001049 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Peroxisome/Stoichiometry/1.0
right: Succinic acid
right: Carbon dioxide
right: 2-Hydroxyphytanoyl-CoA
spontaneous: false
EC number: 1.14.11.18
left: Oxygen
left: Oxoglutaric acid
left: Phytanoyl-CoA
name: Oxoglutaric acid + Oxygen + Phytanoyl-CoA → 2-Hydroxyphytanoyl-CoA + Carbon dioxide + Succinic acid
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15522
type: UnificationXref
id: CHEBI:15522
db: ChEBI

Compound/PW C000999 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Hydroxyphytanoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 541-15-1
type: UnificationXref
id: 541-15-1
db: CAS

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

ChemicalStructure/PW C000129
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C

Compound/PW C001099 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/UniProt Q642G4
type: UnificationXref
id: Q642G4
db: UniProt

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

4,8 Dimethylnonanoyl carnitine
type: SmallMolecule
cellular location: Peroxisome
entity reference: 4,8 Dimethylnonanoyl carnitine

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

2-hydroxyacyl-CoA lyase 1
type: Protein
cellular location: Peroxisome
entity reference: 2-hydroxyacyl-CoA lyase 1

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

4.1.-.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000999 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001309 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001883 Peroxisome/Stoichiometry/1.0
right: Pristanal
right: Formyl-CoA
spontaneous: false
EC number: 4.1.-.-
left: 2-Hydroxyphytanoyl-CoA
name: 2-Hydroxyphytanoyl-CoA → Formyl-CoA + Pristanal
conversion direction: LEFT_TO_RIGHT

6.2.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001034 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000639 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001049 Peroxisome Membrane/Stoichiometry/1.0
right: Pyrophosphate
right: Adenosine diphosphate
right: Phytanoyl-CoA
spontaneous: false
EC number: 6.2.1.3
left: Phytanic acid
left: Coenzyme A
left: Adenosine triphosphate
name: Adenosine triphosphate + Coenzyme A + Phytanic acid → Adenosine diphosphate + Phytanoyl-CoA + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C000635 Peroxisome Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanic acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Adenosine triphosphate
type: SmallMolecule
cellular location: Peroxisome Membrane
entity reference: Adenosine triphosphate

Phytanoyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-206
xref: Reference/HMDB HMDB0001359
xref: Reference/CAS 146622-45-9
xref: Reference/KEGG Compound C02060
xref: Reference/PubChem-compound 439640
xref: Reference/ChemSpider 388712
xref: Reference/ChEBI CHEBI 15538
chemical formula: C41H74N7O17P3S
molecular weight: 1061.4075
structure: ChemicalStructure/PW C001049

Compound/PW C001099 Peroxisome Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Protein/15925 Peroxisome/Stoichiometry/4.0
type: Stoichiometry
physical entity: 2-hydroxyacyl-CoA lyase 1
stoichiometric coefficient: 4.0

Reference/UniProt Q8CHM7
type: UnificationXref
id: Q8CHM7
db: UniProt

Compound/PW C001049 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phytanoyl-CoA
stoichiometric coefficient: 1.0

Reference/GENE ONTOLOGY GO 0005758
type: UnificationXref
id: GO:0005758
db: GENE ONTOLOGY

Reference/GENE ONTOLOGY GO 0005759
type: UnificationXref
id: GO:0005759
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 15741
type: UnificationXref
id: CHEBI:15741
db: ChEBI

Compound/PW C000940 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/PubChem-compound 1110
type: UnificationXref
id: 1110
db: PubChem-compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

L-Carnitine
type: SmallMolecule
cellular location: Mitochondrion
entity reference: L-Carnitine

Compound/PW C001049 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phytanoyl-CoA
stoichiometric coefficient: 1.0

Succinic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000254
xref: Reference/CAS 110-15-6
xref: Reference/ChEBI CHEBI 15741
xref: Reference/KEGG Compound C00042
xref: Reference/ChemSpider 1078
xref: Reference/PubChem-compound 1110
xref: Reference/BioCyc SUC
chemical formula: C4H6O4
molecular weight: 118.02661
structure: ChemicalStructure/PW C000174

Pristanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C07297
xref: Reference/ChemSpider 390025
xref: Reference/BioCyc 3-OXOPRISTANOYL-COA
xref: Reference/PubChem-compound 441253
xref: Reference/HMDB HMDB0002057
xref: Reference/ChEBI CHEBI 28542
chemical formula: C40H70N7O18P3S
molecular weight: 1061.3711
structure: ChemicalStructure/PW C001381

Reference/BioCyc CPD-206
type: UnificationXref
id: CPD-206
db: BioCyc

Compound/PW C000174 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C002659
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)CCCC(C)CCC(=O)OC(CC([O-])=O)C[N+](C)(C)C

Beta Oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108670
pathway component: SubPathwayInteraction108670
name: SubPathway

Beta Oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108671
pathway component: SubPathwayInteraction108671
name: SubPathway

Reference/GENE ONTOLOGY GO 0005739
type: UnificationXref
id: GO:0005739
db: GENE ONTOLOGY

Reference/KEGG Compound C07343
type: UnificationXref
id: C07343
db: KEGG Compound

Compound/PW C002659 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4,8 Dimethylnonanoyl carnitine
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Reference/PubChem-compound 439640
type: UnificationXref
id: 439640
db: PubChem-compound

Reference/SMPDB SMP0087348
type: UnificationXref
id: SMP0087348
db: SMPDB

Pristanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Pristanoyl-CoA
name: SubPathwayInput

Reference/HMDB HMDB0000801
type: UnificationXref
id: HMDB0000801
db: HMDB

Reference/ChemSpider 21233922
type: UnificationXref
id: 21233922
db: ChemSpider

Reference/TAXONOMY 10116
type: UnificationXref
id: 10116
db: TAXONOMY

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Reference/PubChem-compound 439313
type: UnificationXref
id: 439313
db: PubChem-compound

Reference/ChemSpider 390032
type: UnificationXref
id: 390032
db: ChemSpider

L-Acetylcarnitine
type: SmallMolecule
cellular location: Peroxisome
entity reference: L-Acetylcarnitine

2-Hydroxyphytanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: 2-Hydroxyphytanoyl-CoA

Mitochondrial Matrix
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005759

Reference/ChemSpider 96904
type: UnificationXref
id: 96904
db: ChemSpider

Reference/ChEBI CHEBI 63874
type: UnificationXref
id: CHEBI:63874
db: ChEBI

Phytanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome Membrane
entity reference: Phytanoyl-CoA

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Compound/PW C000129 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Peroxisomal membrane protein
type: Complex
component stoichiometry: Protein/7758/Stoichiometry/1.0
component stoichiometry: Protein/14622/Stoichiometry/1.0
component: Unknown
component: Peroxisomal membrane protein PEX14

ATP-binding cassette sub-family D member 2
type: Protein
entity reference: ATP-binding cassette sub-family D member 2

Reference/ChemSpider 1078
type: UnificationXref
id: 1078
db: ChemSpider

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Oxygen
type: SmallMolecule
cellular location: Peroxisome
entity reference: Oxygen

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/PubChem-compound 10917
type: UnificationXref
id: 10917
db: PubChem-compound

Aldehyde dehydrogenase, mitochondrial
type: Complex
component stoichiometry: Protein/15360 Mitochondrion/Stoichiometry/4.0
cellular location: Mitochondrion
component: Aldehyde dehydrogenase, mitochondrial

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Reference/ChemSpider 10455
type: UnificationXref
id: 10455
db: ChemSpider

ReactionCatalysis138248
type: Catalysis
controller: Carnitine O-palmitoyltransferase 1, brain isoform
controlled: 2.3.1.7
control type: ACTIVATION

ReactionCatalysis138247
type: Catalysis
controller: Carnitine O-palmitoyltransferase 1, brain isoform
controlled: Reaction147981
control type: ACTIVATION

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Pristanic acid
type: SmallMolecule
cellular location: Peroxisome Membrane
entity reference: Pristanic acid

ReactionCatalysis138244
type: Catalysis
controller: Long-chain-fatty-acid--CoA ligase ACSBG2
controlled: 6.2.1.3
control type: ACTIVATION

Coenzyme A
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Coenzyme A

Reference/UniProt A1L1K7
type: UnificationXref
id: A1L1K7
db: UniProt

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

ReactionCatalysis138246
type: Catalysis
controller: Carnitine O-palmitoyltransferase 1, brain isoform
controlled: 2.3.1.7
control type: ACTIVATION

Compound/PW C001381 Peroxisome Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanoyl-CoA
stoichiometric coefficient: 1.0

ReactionCatalysis138245
type: Catalysis
controller: Aldehyde dehydrogenase, mitochondrial
controlled: 1.2.1.3
control type: ACTIVATION

Reference/HMDB HMDB0000824
type: UnificationXref
id: HMDB0000824
db: HMDB

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Reference/ChEBI CHEBI 28867
type: UnificationXref
id: CHEBI:28867
db: ChEBI

Reference/ChEBI CHEBI 15539
type: UnificationXref
id: CHEBI:15539
db: ChEBI

Reference/ChEBI CHEBI 15538
type: UnificationXref
id: CHEBI:15538
db: ChEBI

Reference/ChemSpider 390025
type: UnificationXref
id: 390025
db: ChemSpider

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C000044 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Carnitine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/GENE ONTOLOGY GO 0005778
type: UnificationXref
id: GO:0005778
db: GENE ONTOLOGY

Reference/HMDB HMDB0011604
type: UnificationXref
id: HMDB0011604
db: HMDB

Reference/GENE ONTOLOGY GO 0005777
type: UnificationXref
id: GO:0005777
db: GENE ONTOLOGY

4,8 Dimethylnonanoyl carnitine
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 4,8 Dimethylnonanoyl carnitine

Coenzyme A
type: SmallMolecule
cellular location: Peroxisome
entity reference: Coenzyme A

Reference/CAS 14721-66-5
type: UnificationXref
id: 14721-66-5
db: CAS

Succinic acid
type: SmallMolecule
cellular location: Peroxisome
entity reference: Succinic acid

Oxoglutaric acid
type: SmallMolecule
cellular location: Peroxisome
entity reference: Oxoglutaric acid

Reference/KEGG Compound C01607
type: UnificationXref
id: C01607
db: KEGG Compound

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

4,8 Dimethylnonanoyl carnitine
type: SmallMolecule
cellular location: Mitochondrial Intermembrane Space
entity reference: 4,8 Dimethylnonanoyl carnitine

Reference/CAS 110-15-6
type: UnificationXref
id: 110-15-6
db: CAS

Reference/PubChem-compound 14671060
type: UnificationXref
id: 14671060
db: PubChem-compound

Compound/PW C000639 Peroxisome Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phytanic acid
stoichiometric coefficient: 1.0

Mitochondrial Intermembrane Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005758

ATP-binding cassette sub-family D member 2
type: ProteinReference
xref: Reference/UniProt Q9QY44

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Reference/ChEBI CHEBI 16347
type: UnificationXref
id: CHEBI:16347
db: ChEBI

Reference/PubChem-compound 107738
type: UnificationXref
id: 107738
db: PubChem-compound

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000658
type: ChemicalStructure
structure format: SMILES
structure data: CCC(=O)OC(CC([O-])=O)C[N+](C)(C)C

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Long-chain-fatty-acid--CoA ligase ACSBG2
type: ProteinReference
xref: Reference/UniProt A1L1K7
organism: Rattus norvegicus

Mitochondrial 2-oxodicarboxylate carrier
type: ProteinReference
xref: Reference/UniProt Q99JD3

Peroxisomal membrane protein PEX14
type: ProteinReference
xref: Reference/UniProt Q642G4

Carnitine O-palmitoyltransferase 1, brain isoform
type: ProteinReference
xref: Reference/UniProt F1LN46
organism: Rattus norvegicus

Unknown
type: ProteinReference

Reference/HMDB HMDB0001958
type: UnificationXref
id: HMDB0001958
db: HMDB

6.2.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001034 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001381 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000635 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Peroxisome Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Peroxisome Membrane/Stoichiometry/1.0
right: Pristanoyl-CoA
right: Pyrophosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 6.2.1.3
left: Pristanic acid
left: Coenzyme A
left: Adenosine triphosphate
name: Adenosine triphosphate + Coenzyme A + Pristanic acid → Adenosine diphosphate + Pristanoyl-CoA + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

1.2.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001309 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001381 Mitochondrion/Stoichiometry/1.0
right: Pristanoyl-CoA
spontaneous: false
EC number: 1.2.1.3
left: Coenzyme A
left: Pristanal
name: Coenzyme A + Pristanal → Pristanoyl-CoA
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000988
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 21243783
type: UnificationXref
id: 21243783
db: ChemSpider

Reference/CAS 146622-45-9
type: UnificationXref
id: 146622-45-9
db: CAS

Reference/KEGG Compound C07297
type: UnificationXref
id: C07297
db: KEGG Compound

Reference/ChEBI CHEBI 28542
type: UnificationXref
id: CHEBI:28542
db: ChEBI

Reference/ChEBI CHEBI 15475
type: UnificationXref
id: CHEBI:15475
db: ChEBI

Compound/PW C000658 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionylcarnitine
stoichiometric coefficient: 1.0

2.3.1.7
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000658 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000658 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000988 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000988 Mitochondrion/Stoichiometry/1.0
right: Coenzyme A
right: Propionylcarnitine
spontaneous: false
EC number: 2.3.1.7
left: L-Carnitine
left: Propionyl-CoA
name: L-Carnitine + Propionyl-CoA ↔ Coenzyme A + Propionylcarnitine
conversion direction: REVERSIBLE

Reaction147981
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002659 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007198 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002659 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007198 Mitochondrion/Stoichiometry/1.0
right: Coenzyme A
right: 4,8 Dimethylnonanoyl carnitine
spontaneous: false
left: L-Carnitine
left: 4,8-Dimethylnonanoyl-CoA
name: 4,8-Dimethylnonanoyl-CoA + L-Carnitine ↔ 4,8 Dimethylnonanoyl carnitine + Coenzyme A
conversion direction: REVERSIBLE

2.3.1.7
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000129 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000129 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Peroxisome/Stoichiometry/1.0
right: Coenzyme A
right: L-Acetylcarnitine
spontaneous: false
EC number: 2.3.1.7
left: L-Carnitine
left: Acetyl-CoA
name: Acetyl-CoA + L-Carnitine ↔ Coenzyme A + L-Acetylcarnitine
conversion direction: REVERSIBLE

ChemicalStructure/PW C000635
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)CCCC(C)CCCC(C)CCCC(C)C(O)=O

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Carnitine O-palmitoyltransferase 1, brain isoform
type: Protein
cellular location: Peroxisome
entity reference: Carnitine O-palmitoyltransferase 1, brain isoform

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

ChemicalStructure/PW C000639
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O)=O

Reference/UniProt Q91ZD7
type: UnificationXref
id: Q91ZD7
db: UniProt

ChemicalStructure/PW C000999
type: ChemicalStructure
structure format: SMILES

Compound/PW C001065 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 1.0

Long-chain-fatty-acid--CoA ligase ACSBG2
type: Protein
cellular location: Peroxisome Membrane
entity reference: Long-chain-fatty-acid--CoA ligase ACSBG2

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS