Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/HMDB HMDB0057423
type: UnificationXref
id: HMDB0057423
db: HMDB

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL-P
db: BioCyc

Reference/PubChem-compound 53481807
type: UnificationXref
id: 53481807
db: PubChem-compound

NADH
type: SmallMolecule
entity reference: NADH

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C003046
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Reference/HMDB HMDB0006995
type: UnificationXref
id: HMDB0006995
db: HMDB

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/ChemSpider 24765835
type: UnificationXref
id: 24765835
db: ChemSpider

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Cardiolipin Biosynthesis CL(16:1(9Z)/16:0/18:1(9Z)/16:0)
type: Pathway
pathway order: PathwayEnzymeReaction/1759408
pathway order: PathwayEnzymeReaction/1759409
pathway order: PathwayEnzymeReaction/1759406
pathway order: PathwayEnzymeReaction/1759407
pathway order: PathwayEnzymeReaction/1759411
pathway order: PathwayEnzymeReaction/1759412
pathway order: PathwayTransport/1759405
pathway order: PathwaySubPathway/86523
pathway order: PathwayEnzymeReaction/1759410
pathway component: Reaction155955
pathway component: ReactionCatalysis136533
pathway component: ReactionCatalysis133079
pathway component: ReactionCatalysis133143
pathway component: Reaction155973
pathway component: ReactionCatalysis133144
pathway component: Transport9105
pathway component: ReactionCatalysis136539
pathway component: ReactionCatalysis136535
pathway component: ReactionCatalysis136537
pathway component: Reaction143007
pathway component: Glycolysis
pathway component: 2.7.8.5
pathway component: 2.7.7.41
pathway component: Reaction151747
pathway component: Reaction155958
xref: Reference/SMPDB SMP0092974
xref: Reference/PathWhiz PW093995
organism: Rattus norvegicus

Compound/PW C000064/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

NAD
type: SmallMolecule
entity reference: NAD

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
type: Protein
entity reference: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

Phosphatidate cytidylyltransferase
type: Protein
entity reference: Phosphatidate cytidylyltransferase

Reference/HMDB HMDB0010585
type: UnificationXref
id: HMDB0010585
db: HMDB

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/UniProt Q5U2V5
type: UnificationXref
id: Q5U2V5
db: UniProt

Compound/PW C037877/Stoichiometry/1.0
type: Stoichiometry
physical entity: CL(16:1(9Z)/16:0/18:1(9Z)/16:0)
stoichiometric coefficient: 1.0

Reference/BioCyc PALMITYL-COA
type: UnificationXref
id: PALMITYL-COA
db: BioCyc

Reaction155955
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001031/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062273/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042972/Stoichiometry/1.0
right: Coenzyme A
right: PA(16:1(9Z)/16:0)
spontaneous: false
left: LPA(16:1(9Z)/0:0)
left: Palmityl-CoA
name: LPA(16:1(9Z)/0:0) + Palmityl-CoA → Coenzyme A + PA(16:1(9Z)/16:0)
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis133079
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
controlled: Reaction143007
control type: ACTIVATION

Reference/UniProt D3ZI76
type: UnificationXref
id: D3ZI76
db: UniProt

1-Acylglycerol-3-phosphate O-acyltransferase 1
type: Protein
entity reference: 1-Acylglycerol-3-phosphate O-acyltransferase 1

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Glycerol-3-phosphate acyltransferase 2, mitochondrial
type: Protein
entity reference: Glycerol-3-phosphate acyltransferase 2, mitochondrial

Glycerol-3-phosphate dehydrogenase [NAD(+)]
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(+)]

Reference/CAS 18198-76-0
type: UnificationXref
id: 18198-76-0
db: CAS

Reaction143007
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: NADH
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH → Glycerol 3-phosphate + NAD
conversion direction: LEFT_TO_RIGHT

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/HMDB HMDB0006532
type: UnificationXref
id: HMDB0006532
db: HMDB

CDP-DG(16:1(9Z)/16:0)
type: SmallMolecule
entity reference: CDP-DG(16:1(9Z)/16:0)

2.7.8.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041065/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C008404/Stoichiometry/1.0
right: Cytidine monophosphate
right: PGP(16:1(9Z)/16:0)
spontaneous: false
EC number: 2.7.8.5
left: CDP-DG(16:1(9Z)/16:0)
left: Glycerol 3-phosphate
name: CDP-DG(16:1(9Z)/16:0) + Glycerol 3-phosphate → Cytidine monophosphate + PGP(16:1(9Z)/16:0)
conversion direction: LEFT_TO_RIGHT

2.7.7.41
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041065/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062273/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
right: CDP-DG(16:1(9Z)/16:0)
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.41
left: Cytidine triphosphate
left: PA(16:1(9Z)/16:0)
name: Cytidine triphosphate + PA(16:1(9Z)/16:0) → CDP-DG(16:1(9Z)/16:0) + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reaction155958
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006593/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C008404/Stoichiometry/1.0
right: PG(16:1(9Z)/16:0)
right: Phosphate
spontaneous: false
left: PGP(16:1(9Z)/16:0)
left: Water
name: PGP(16:1(9Z)/16:0) + Water → PG(16:1(9Z)/16:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

PG(16:1(9Z)/16:0)
type: SmallMoleculeReference
xref: Reference/ChemSpider 24768084
xref: Reference/ChEBI CHEBI 17517
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
xref: Reference/HMDB HMDB0010585
xref: Reference/KEGG Compound C00344
xref: Reference/PubChem-compound 52926472
chemical formula: C38H73O10P
molecular weight: 720.49414
structure: ChemicalStructure/PW C006593

Palmitoleyl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 53477852
xref: Reference/HMDB HMDB0006532
xref: Reference/ChEBI CHEBI 53152
xref: Reference/CAS 18198-76-0
chemical formula: C37H64N7O17P3S
molecular weight: 1003.3292
structure: ChemicalStructure/PW C002798

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/KEGG Compound C00344
type: UnificationXref
id: C00344
db: KEGG Compound

Reference/BioCyc CARDIOLIPIN
type: UnificationXref
id: CARDIOLIPIN
db: BioCyc

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

CL(16:1(9Z)/16:0/18:1(9Z)/16:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05980
xref: Reference/HMDB HMDB0057423
xref: Reference/ChEBI CHEBI 28494
xref: Reference/BioCyc CARDIOLIPIN
chemical formula: C75H142O17P2
molecular weight: 1376.9722
structure: ChemicalStructure/PW C037877

Rattus norvegicus
type: BioSource
xref: Reference/TAXONOMY 10116

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

ChemicalStructure/PW C062273
type: ChemicalStructure
structure format: SMILES

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

PA(16:1(9Z)/16:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/HMDB HMDB0114855
xref: Reference/ChEBI CHEBI 16337
chemical formula: C35H67O8P
molecular weight: 646.45734
structure: ChemicalStructure/PW C062273

SubPathwayInteraction86523
type: Interaction
name: SubPathway86523Reaction
name: SubPathwayReaction
participant: Dihydroxyacetone phosphate

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Compound/PW C001031/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmityl-CoA
stoichiometric coefficient: 1.0

Reaction155973
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003046/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006593/Stoichiometry/1.0
participant stoichiometry: Compound/PW C037877/Stoichiometry/1.0
right: Cytidine monophosphate
right: CL(16:1(9Z)/16:0/18:1(9Z)/16:0)
spontaneous: false
left: CDP-DG(18:1(9Z)/16:0)
left: PG(16:1(9Z)/16:0)
name: CDP-DG(18:1(9Z)/16:0) + PG(16:1(9Z)/16:0) → CL(16:1(9Z)/16:0/18:1(9Z)/16:0) + Cytidine monophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15525
type: UnificationXref
id: CHEBI:15525
db: ChEBI

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C002798
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Compound/PW C062273 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(16:1(9Z)/16:0)
stoichiometric coefficient: 1.0

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Cardiolipin synthase (CMP-forming)
type: Protein
entity reference: Cardiolipin synthase (CMP-forming)

ChemicalStructure/PW C006593
type: ChemicalStructure
structure format: SMILES

Phosphatidate cytidylyltransferase
type: ProteinReference
xref: Reference/UniProt G3V8W2

Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
type: ProteinReference
xref: Reference/UniProt G3V7B6

Reference/SMPDB SMP0087317
type: UnificationXref
id: SMP0087317
db: SMPDB

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/PubChem-compound 53477852
type: UnificationXref
id: 53477852
db: PubChem-compound

ChemicalStructure/PW C042972
type: ChemicalStructure
structure format: SMILES
structure data: [H]\C(CCCCCC)=C(/[H])CCCCCCCC(=O)OCC(O)COP(O)(O)=O

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/CAS 1763-10-6
type: UnificationXref
id: 1763-10-6
db: CAS

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/PathWhiz PW088336
type: UnificationXref
id: PW088336
db: PathWhiz

Compound/PW C041065/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(16:1(9Z)/16:0)
stoichiometric coefficient: 1.0

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: Protein
entity reference: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway86523
pathway component: SubPathwayInteraction86523
xref: Reference/SMPDB SMP0087317
xref: Reference/PathWhiz PW088336
name: SubPathway

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

ChemicalStructure/PW C037877
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Complex
component stoichiometry: Protein/17700/Stoichiometry/2.0
component: Glycerol-3-phosphate dehydrogenase [NAD(+)]

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

PA(16:1(9Z)/16:0)
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: PA(16:1(9Z)/16:0)

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Reference/ChemSpider 24768084
type: UnificationXref
id: 24768084
db: ChemSpider

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Reference/GENE ONTOLOGY GO 0005741
type: UnificationXref
id: GO:0005741
db: GENE ONTOLOGY

Protein/17700/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glycerol-3-phosphate dehydrogenase [NAD(+)]
stoichiometric coefficient: 2.0

Compound/PW C062273 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(16:1(9Z)/16:0)
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL
db: BioCyc

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00269
type: UnificationXref
id: C00269
db: KEGG Compound

Reference/KEGG Compound C03892
type: UnificationXref
id: C03892
db: KEGG Compound

Cytidine monophosphate
type: SmallMolecule
entity reference: Cytidine monophosphate

Palmityl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 15667
xref: Reference/ChemSpider 14902
xref: Reference/HMDB HMDB0001338
xref: Reference/ChEBI CHEBI 15525
xref: Reference/KEGG Compound C00154
xref: Reference/CAS 1763-10-6
xref: Reference/BioCyc PALMITYL-COA
chemical formula: C37H66N7O17P3S
molecular weight: 1005.34485
structure: ChemicalStructure/PW C001031

Reference/HMDB HMDB0114855
type: UnificationXref
id: HMDB0114855
db: HMDB

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

ChemicalStructure/PW C008404
type: ChemicalStructure
structure format: SMILES

Palmityl-CoA
type: SmallMolecule
entity reference: Palmityl-CoA

Reference/HMDB HMDB0001338
type: UnificationXref
id: HMDB0001338
db: HMDB

Reference/ChEBI CHEBI 28494
type: UnificationXref
id: CHEBI:28494
db: ChEBI

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

Compound/PW C002798/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmitoleyl-CoA
stoichiometric coefficient: 1.0

Mitochondrial Outer Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005741

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00154
type: UnificationXref
id: C00154
db: KEGG Compound

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/TAXONOMY 10116
type: UnificationXref
id: 10116
db: TAXONOMY

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

CDP-DG(18:1(9Z)/16:0)
type: SmallMolecule
entity reference: CDP-DG(18:1(9Z)/16:0)

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Compound/PW C062273/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(16:1(9Z)/16:0)
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 75070
type: UnificationXref
id: CHEBI:75070
db: ChEBI

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/UniProt G3V8W2
type: UnificationXref
id: G3V8W2
db: UniProt

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

ReactionCatalysis136533
type: Catalysis
controller: Phosphatidate cytidylyltransferase
controlled: 2.7.7.41
control type: ACTIVATION

Reference/ChEBI CHEBI 17517
type: UnificationXref
id: CHEBI:17517
db: ChEBI

ReactionCatalysis133143
type: Catalysis
controller: Glycerol-3-phosphate acyltransferase 2, mitochondrial
controlled: Reaction151747
control type: ACTIVATION

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

ReactionCatalysis133144
type: Catalysis
controller: 1-Acylglycerol-3-phosphate O-acyltransferase 1
controlled: Reaction155955
control type: ACTIVATION

ReactionCatalysis136539
type: Catalysis
controller: Cardiolipin synthase (CMP-forming)
controlled: Reaction155973
control type: ACTIVATION

Compound/PW C006593/Stoichiometry/1.0
type: Stoichiometry
physical entity: PG(16:1(9Z)/16:0)
stoichiometric coefficient: 1.0

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

ReactionCatalysis136535
type: Catalysis
controller: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
controlled: 2.7.8.5
control type: ACTIVATION

ReactionCatalysis136537
type: Catalysis
controller: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
controlled: Reaction155958
control type: ACTIVATION

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

ChemicalStructure/PW C001031
type: ChemicalStructure
structure format: SMILES

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C05980
type: UnificationXref
id: C05980
db: KEGG Compound

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: ProteinReference
xref: Reference/UniProt D4A5W8

PA(16:1(9Z)/16:0)
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: PA(16:1(9Z)/16:0)

Reference/PubChem-compound 53477938
type: UnificationXref
id: 53477938
db: PubChem-compound

PA(16:1(9Z)/16:0)
type: SmallMolecule
entity reference: PA(16:1(9Z)/16:0)

Reference/PubChem-compound 52926472
type: UnificationXref
id: 52926472
db: PubChem-compound

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reaction151747
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002798/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042972/Stoichiometry/1.0
right: Coenzyme A
right: LPA(16:1(9Z)/0:0)
spontaneous: false
left: Palmitoleyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Palmitoleyl-CoA → Coenzyme A + LPA(16:1(9Z)/0:0)
conversion direction: LEFT_TO_RIGHT

Reference/UniProt D3ZAP9
type: UnificationXref
id: D3ZAP9
db: UniProt

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Reference/ChemSpider 14902
type: UnificationXref
id: 14902
db: ChemSpider

Reference/ChEBI CHEBI 17962
type: UnificationXref
id: CHEBI:17962
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Reference/UniProt G3V7B6
type: UnificationXref
id: G3V7B6
db: UniProt

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Cardiolipin synthase (CMP-forming)
type: ProteinReference
xref: Reference/UniProt Q5U2V5

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Reference/BioCyc CDPDIACYLGLYCEROL
type: UnificationXref
id: CDPDIACYLGLYCEROL
db: BioCyc

Reference/UniProt D4A5W8
type: UnificationXref
id: D4A5W8
db: UniProt

ChemicalStructure/PW C041065
type: ChemicalStructure
structure format: SMILES

Compound/PW C003046/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(18:1(9Z)/16:0)
stoichiometric coefficient: 1.0

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Transport9105
type: Transport
participant stoichiometry: Compound/PW C062273 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062273 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: PA(16:1(9Z)/16:0)
spontaneous: false
left: PA(16:1(9Z)/16:0)
name: PA(16:1(9Z)/16:0) (→) Transport: Rattus norvegicus, Cell, Mitochondrial Outer Membrane to Rattus norvegicus, Cell, Mitochondrial Inner Membrane
conversion direction: LEFT_TO_RIGHT

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0092974
type: UnificationXref
id: SMP0092974
db: SMPDB

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

CL(16:1(9Z)/16:0/18:1(9Z)/16:0)
type: SmallMolecule
entity reference: CL(16:1(9Z)/16:0/18:1(9Z)/16:0)

Glycerol-3-phosphate dehydrogenase [NAD(+)]
type: ProteinReference
xref: Reference/UniProt D3ZAP9

Compound/PW C042972/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(16:1(9Z)/0:0)
stoichiometric coefficient: 1.0

Glycerol-3-phosphate acyltransferase 2, mitochondrial
type: ProteinReference
xref: Reference/UniProt D3ZI76

1-Acylglycerol-3-phosphate O-acyltransferase 1
type: ProteinReference

Reference/HMDB HMDB0013487
type: UnificationXref
id: HMDB0013487
db: HMDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/ChEBI CHEBI 37393
type: UnificationXref
id: CHEBI:37393
db: ChEBI

LPA(16:1(9Z)/0:0)
type: SmallMolecule
entity reference: LPA(16:1(9Z)/0:0)

Palmitoleyl-CoA
type: SmallMolecule
entity reference: Palmitoleyl-CoA

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

PG(16:1(9Z)/16:0)
type: SmallMolecule
entity reference: PG(16:1(9Z)/16:0)

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

CDP-DG(16:1(9Z)/16:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17962
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/KEGG Compound C00269
chemical formula: C44H79N3O15P2
molecular weight: 951.49866
structure: ChemicalStructure/PW C041065

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

PGP(16:1(9Z)/16:0)
type: SmallMolecule
entity reference: PGP(16:1(9Z)/16:0)

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

PGP(16:1(9Z)/16:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0013487
xref: Reference/ChEBI CHEBI 37393
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
xref: Reference/KEGG Compound C03892
xref: Reference/PubChem-compound 53481807
chemical formula: C38H74O13P2
molecular weight: 800.46045
structure: ChemicalStructure/PW C008404

Reference/PathWhiz PW093995
type: UnificationXref
id: PW093995
db: PathWhiz

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

CDP-DG(18:1(9Z)/16:0)
type: SmallMoleculeReference
xref: Reference/ChemSpider 24765835
xref: Reference/ChEBI CHEBI 17962
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/HMDB HMDB0006995
xref: Reference/PubChem-compound 53477938
xref: Reference/KEGG Compound C00269
chemical formula: C46H83N3O15P2
molecular weight: 979.52997
structure: ChemicalStructure/PW C003046

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Compound/PW C008404/Stoichiometry/1.0
type: Stoichiometry
physical entity: PGP(16:1(9Z)/16:0)
stoichiometric coefficient: 1.0

Reference/PubChem-compound 15667
type: UnificationXref
id: 15667
db: PubChem-compound

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

LPA(16:1(9Z)/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 75070
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
chemical formula: C19H37O7P
molecular weight: 408.2277
structure: ChemicalStructure/PW C042972

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 53152
type: UnificationXref
id: CHEBI:53152
db: ChEBI

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O