Compound/PW C055528 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(14:1(9Z)/15:0)
stoichiometric coefficient: 1.0

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

NADH
type: SmallMolecule
entity reference: NADH

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

ChemicalStructure/PW C102485
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Phosphatidate cytidylyltransferase
type: ProteinReference
xref: Reference/UniProt B6IDT4

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Compound/PW C000064/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

Compound/PW C102485/Stoichiometry/1.0
type: Stoichiometry
physical entity: PG(14:1(9Z)/15:0)
stoichiometric coefficient: 1.0

ChemicalStructure/PW C062920
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C062921
type: ChemicalStructure
structure format: SMILES

NAD
type: SmallMolecule
entity reference: NAD

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

BcDNA.GH07066
type: ProteinReference
xref: Reference/UniProt Q9Y137

ChemicalStructure/PW C103104
type: ChemicalStructure
structure format: SMILES

Cardiolipin Biosynthesis CL(14:1(9Z)/15:0/20:1(11Z)/22:0)
type: Pathway
pathway order: PathwayEnzymeReaction/1849445
pathway order: PathwayEnzymeReaction/1849444
pathway order: PathwayEnzymeReaction/1849443
pathway order: PathwaySubPathway/90752
pathway order: PathwayEnzymeReaction/1849442
pathway order: PathwayEnzymeReaction/1849439
pathway order: PathwayEnzymeReaction/1849441
pathway order: PathwayEnzymeReaction/1849440
pathway order: PathwayTransport/1849438
pathway component: Reaction159106
pathway component: Reaction160862
pathway component: Glycolysis
pathway component: 2.7.7.41
pathway component: Reaction159256
pathway component: ReactionCatalysis149484
pathway component: Reaction160768
pathway component: ReactionCatalysis149483
pathway component: 2.7.8.5
pathway component: Reaction159241
pathway component: ReactionCatalysis149488
pathway component: ReactionCatalysis149476
pathway component: ReactionCatalysis149487
pathway component: Transport9253
pathway component: ReactionCatalysis149486
pathway component: ReactionCatalysis149485
xref: Reference/SMPDB SMP0097197
xref: Reference/PathWhiz PW098220
organism: Drosophila melanogaster

1-Acyl-sn-glycerol-3-phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt Q9VYJ4

Reaction160862
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C102485/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045684/Stoichiometry/1.0
participant stoichiometry: Compound/PW C103104/Stoichiometry/1.0
right: Cytidine monophosphate
right: CL(14:1(9Z)/15:0/20:1(11Z)/22:0)
spontaneous: false
left: CDP-DG(20:1(11Z)/22:0)
left: PG(14:1(9Z)/15:0)
name: CDP-DG(20:1(11Z)/22:0) + PG(14:1(9Z)/15:0) → CL(14:1(9Z)/15:0/20:1(11Z)/22:0) + Cytidine monophosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

ChemicalStructure/PW C045380
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

PA(14:1(9Z)/15:0)
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: PA(14:1(9Z)/15:0)

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Compound/PW C055528/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(14:1(9Z)/15:0)
stoichiometric coefficient: 1.0

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Protein/15684/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
stoichiometric coefficient: 2.0

Compound/PW C045684/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(20:1(11Z)/22:0)
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0112236
type: UnificationXref
id: HMDB0112236
db: HMDB

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Compound/PW C045380/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(14:1(9Z)/15:0)
stoichiometric coefficient: 1.0

Drosophila melanogaster
type: BioSource
xref: Reference/TAXONOMY 7227

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

Compound/PW C055365/Stoichiometry/1.0
type: Stoichiometry
physical entity: LPA(14:1(9Z)/0:0)
stoichiometric coefficient: 1.0

Reference/BioCyc CPD-14724
type: UnificationXref
id: CPD-14724
db: BioCyc

CL(14:1(9Z)/15:0/20:1(11Z)/22:0)
type: SmallMoleculeReference
chemical formula: C80H152O17P2
molecular weight: 1447.0505
structure: ChemicalStructure/PW C103104

Reference/ChEBI CHEBI 16975
type: UnificationXref
id: CHEBI:16975
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

2.7.7.41
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055528/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045380/Stoichiometry/1.0
right: CDP-DG(14:1(9Z)/15:0)
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.41
left: Cytidine triphosphate
left: PA(14:1(9Z)/15:0)
name: Cytidine triphosphate + PA(14:1(9Z)/15:0) → CDP-DG(14:1(9Z)/15:0) + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reaction160768
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C102464/Stoichiometry/1.0
participant stoichiometry: Compound/PW C102485/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: PG(14:1(9Z)/15:0)
right: Phosphate
spontaneous: false
left: Water
left: PGP(14:1(9Z)/15:0)
name: PGP(14:1(9Z)/15:0) + Water → PG(14:1(9Z)/15:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

2.7.8.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C102464/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045380/Stoichiometry/1.0
right: Cytidine monophosphate
right: PGP(14:1(9Z)/15:0)
spontaneous: false
EC number: 2.7.8.5
left: CDP-DG(14:1(9Z)/15:0)
left: Glycerol 3-phosphate
name: CDP-DG(14:1(9Z)/15:0) + Glycerol 3-phosphate → Cytidine monophosphate + PGP(14:1(9Z)/15:0)
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C055365
type: ChemicalStructure
structure format: SMILES
structure data: CCCC\C=C/CCCCCCCC(=O)OCC(O)COP(O)(O)=O

Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
type: Protein
entity reference: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

CDP-DG(14:1(9Z)/15:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17962
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/KEGG Compound C00269
chemical formula: C41H73N3O15P2
molecular weight: 909.4517
structure: ChemicalStructure/PW C045380

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Probable cardiolipin synthase (CMP-forming)
type: Protein
entity reference: Probable cardiolipin synthase (CMP-forming)

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C045684
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

PG(14:1(9Z)/15:0)
type: SmallMoleculeReference
chemical formula: C35H67O10P
molecular weight: 678.4472
structure: ChemicalStructure/PW C102485

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: Protein
entity reference: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Transport9253
type: Transport
participant stoichiometry: Compound/PW C055528 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055528 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: PA(14:1(9Z)/15:0)
spontaneous: false
left: PA(14:1(9Z)/15:0)
name: PA(14:1(9Z)/15:0) (→) Transport: Drosophila melanogaster, Cell, Mitochondrial Outer Membrane to Drosophila melanogaster, Cell, Mitochondrial Inner Membrane
conversion direction: LEFT_TO_RIGHT

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

Reference/ChEBI CHEBI 74574
type: UnificationXref
id: CHEBI:74574
db: ChEBI

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

Reference/UniProt B6IDT4
type: UnificationXref
id: B6IDT4
db: UniProt

Compound/PW C103104/Stoichiometry/1.0
type: Stoichiometry
physical entity: CL(14:1(9Z)/15:0/20:1(11Z)/22:0)
stoichiometric coefficient: 1.0

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/ChEBI CHEBI 65087
type: UnificationXref
id: CHEBI:65087
db: ChEBI

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

PA(14:1(9Z)/15:0)
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: PA(14:1(9Z)/15:0)

Reference/UniProt Q9VYJ4
type: UnificationXref
id: Q9VYJ4
db: UniProt

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Reference/PubChem-compound 71581247
type: UnificationXref
id: 71581247
db: PubChem-compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Reference/GENE ONTOLOGY GO 0005741
type: UnificationXref
id: GO:0005741
db: GENE ONTOLOGY

PGP(14:1(9Z)/15:0)
type: SmallMolecule
entity reference: PGP(14:1(9Z)/15:0)

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: ProteinReference
xref: Reference/UniProt Q9VML0

Reference/UniProt Q9VE36
type: UnificationXref
id: Q9VE36
db: UniProt

PGP(14:1(9Z)/15:0)
type: SmallMoleculeReference
chemical formula: C35H68O13P2
molecular weight: 758.4135
structure: ChemicalStructure/PW C102464

Reference/UniProt Q9VBN4
type: UnificationXref
id: Q9VBN4
db: UniProt

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00269
type: UnificationXref
id: C00269
db: KEGG Compound

Cytidine monophosphate
type: SmallMolecule
entity reference: Cytidine monophosphate

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

PA(14:1(9Z)/15:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
chemical formula: C32H61O8P
molecular weight: 604.4104
structure: ChemicalStructure/PW C055528

PA(14:1(9Z)/15:0)
type: SmallMolecule
entity reference: PA(14:1(9Z)/15:0)

Reference/UniProt Q9Y137
type: UnificationXref
id: Q9Y137
db: UniProt

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

Reference/TAXONOMY 7227
type: UnificationXref
id: 7227
db: TAXONOMY

Mitochondrial Outer Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005741

Reference/PathWhiz PW098220
type: UnificationXref
id: PW098220
db: PathWhiz

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

PG(14:1(9Z)/15:0)
type: SmallMolecule
entity reference: PG(14:1(9Z)/15:0)

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reaction159106
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: NADH
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH → Glycerol 3-phosphate + NAD
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Reference/PathWhiz PW088410
type: UnificationXref
id: PW088410
db: PathWhiz

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: ProteinReference
xref: Reference/UniProt Q9VE36

Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
type: ProteinReference
xref: Reference/UniProt Q9VCI6

Reference/PubChem-compound 70678650
type: UnificationXref
id: 70678650
db: PubChem-compound

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Reference/ChEBI CHEBI 17962
type: UnificationXref
id: CHEBI:17962
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Pentadecanoyl-CoA
type: SmallMolecule
entity reference: Pentadecanoyl-CoA

Myristoleoyl-CoA
type: SmallMolecule
entity reference: Myristoleoyl-CoA

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

CDP-DG(14:1(9Z)/15:0)
type: SmallMolecule
entity reference: CDP-DG(14:1(9Z)/15:0)

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Probable cardiolipin synthase (CMP-forming)
type: ProteinReference
xref: Reference/UniProt Q9VBN4

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Pentadecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 74574
xref: Reference/BioCyc CPD-14724
xref: Reference/PubChem-compound 71581247
xref: Reference/HMDB HMDB0062518
chemical formula: C36H64N7O17P3S
molecular weight: 991.3292
structure: ChemicalStructure/PW C062921

Reference/BioCyc CDPDIACYLGLYCEROL
type: UnificationXref
id: CDPDIACYLGLYCEROL
db: BioCyc

Myristoleoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 65087
xref: Reference/HMDB HMDB0112236
xref: Reference/CAS 87935-97-5
xref: Reference/PubChem-compound 70678650
chemical formula: C35H60N7O17P3S
molecular weight: 975.2979
structure: ChemicalStructure/PW C062920

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

1-Acyl-sn-glycerol-3-phosphate acyltransferase
type: Protein
entity reference: 1-Acyl-sn-glycerol-3-phosphate acyltransferase

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reaction159241
type: BiochemicalReaction
participant stoichiometry: Compound/PW C055365/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062920/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
right: Coenzyme A
right: LPA(14:1(9Z)/0:0)
spontaneous: false
left: Myristoleoyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Myristoleoyl-CoA → Coenzyme A + LPA(14:1(9Z)/0:0)
conversion direction: LEFT_TO_RIGHT

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

Compound/PW C055528 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(14:1(9Z)/15:0)
stoichiometric coefficient: 1.0

Compound/PW C062920/Stoichiometry/1.0
type: Stoichiometry
physical entity: Myristoleoyl-CoA
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

CL(14:1(9Z)/15:0/20:1(11Z)/22:0)
type: SmallMolecule
entity reference: CL(14:1(9Z)/15:0/20:1(11Z)/22:0)

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reaction159256
type: BiochemicalReaction
participant stoichiometry: Compound/PW C055365/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055528/Stoichiometry/1.0
right: Coenzyme A
right: PA(14:1(9Z)/15:0)
spontaneous: false
left: Pentadecanoyl-CoA
left: LPA(14:1(9Z)/0:0)
name: LPA(14:1(9Z)/0:0) + Pentadecanoyl-CoA → Coenzyme A + PA(14:1(9Z)/15:0)
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis149484
type: Catalysis
controller: 1-Acyl-sn-glycerol-3-phosphate acyltransferase
controlled: Reaction159256
control type: ACTIVATION

ReactionCatalysis149483
type: Catalysis
controller: BcDNA.GH07066
controlled: Reaction159241
control type: ACTIVATION

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/SMPDB SMP0087391
type: UnificationXref
id: SMP0087391
db: SMPDB

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

ReactionCatalysis149488
type: Catalysis
controller: Probable cardiolipin synthase (CMP-forming)
controlled: Reaction160862
control type: ACTIVATION

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ReactionCatalysis149487
type: Catalysis
controller: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
controlled: Reaction160768
control type: ACTIVATION

ReactionCatalysis149486
type: Catalysis
controller: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
controlled: 2.7.8.5
control type: ACTIVATION

ReactionCatalysis149485
type: Catalysis
controller: Phosphatidate cytidylyltransferase
controlled: 2.7.7.41
control type: ACTIVATION

Reference/SMPDB SMP0097197
type: UnificationXref
id: SMP0097197
db: SMPDB

Compound/PW C102464/Stoichiometry/1.0
type: Stoichiometry
physical entity: PGP(14:1(9Z)/15:0)
stoichiometric coefficient: 1.0

CDP-DG(20:1(11Z)/22:0)
type: SmallMolecule
entity reference: CDP-DG(20:1(11Z)/22:0)

Reference/CAS 87935-97-5
type: UnificationXref
id: 87935-97-5
db: CAS

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/UniProt Q9VCI6
type: UnificationXref
id: Q9VCI6
db: UniProt

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

SubPathwayInteraction90752
type: Interaction
name: SubPathway90752Reaction
name: SubPathwayReaction
participant: Dihydroxyacetone phosphate

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

BcDNA.GH07066
type: Protein
entity reference: BcDNA.GH07066

ReactionCatalysis149476
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
controlled: Reaction159106
control type: ACTIVATION

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

ChemicalStructure/PW C055528
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@](COC(=O)CCCCCCC\C=C/CCCC)(COP(O)(O)=O)OC(=O)CCCCCCCCCCCCCC

Phosphatidate cytidylyltransferase
type: Protein
entity reference: Phosphatidate cytidylyltransferase

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway90752
pathway component: SubPathwayInteraction90752
xref: Reference/PathWhiz PW088410
xref: Reference/SMPDB SMP0087391
name: SubPathway

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

LPA(14:1(9Z)/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16975
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
chemical formula: C17H33O7P
molecular weight: 380.19638
structure: ChemicalStructure/PW C055365

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C102464
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

CDP-DG(20:1(11Z)/22:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17962
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/KEGG Compound C00269
chemical formula: C54H99N3O15P2
molecular weight: 1091.6552
structure: ChemicalStructure/PW C045684

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Complex
component stoichiometry: Protein/15684/Stoichiometry/2.0
component: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Compound/PW C062921/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pentadecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

LPA(14:1(9Z)/0:0)
type: SmallMolecule
entity reference: LPA(14:1(9Z)/0:0)

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/HMDB HMDB0062518
type: UnificationXref
id: HMDB0062518
db: HMDB

Reference/UniProt Q9VML0
type: UnificationXref
id: Q9VML0
db: UniProt

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O