Protein/20356/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coagulation factor XI
stoichiometric coefficient: 1.0

Tenase complex
type: Complex
cellular location: Extracellular Space
component: Coagulation factor VIII
component: Coagulation factor IX

Reference/UniProt Q91VP2
type: UnificationXref
id: Q91VP2
db: UniProt

Reference/UniProt Q91ZP0
type: UnificationXref
id: Q91ZP0
db: UniProt

Compound/PW C002089/Stoichiometry/1.0
type: Stoichiometry
physical entity: Reduced Vitamin K (phylloquinone)
stoichiometric coefficient: 1.0

Reference/KEGG Compound C05849
type: UnificationXref
id: C05849
db: KEGG Compound

Reference/UniProt Q8BIP2
type: UnificationXref
id: Q8BIP2
db: UniProt

Protein/20390 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Plasminogen
stoichiometric coefficient: 1.0

Coagulation factor X
type: ProteinReference
xref: Reference/UniProt Q99L32
organism: Mus musculus

Coagulation factor V
type: ProteinReference
xref: Reference/UniProt Q3UV80
organism: Mus musculus

Fibrinogen gamma chain
type: Protein
cellular location: Extracellular Space
entity reference: Fibrinogen gamma chain

Reference/UniProt B1AY02
type: UnificationXref
id: B1AY02
db: UniProt

Tissue factor
type: ProteinReference
xref: Reference/UniProt P20352

Coagulation factor VIII
type: ProteinReference
xref: Reference/UniProt A2AN88
organism: Mus musculus

Reference/PubChem-compound 5284607
type: UnificationXref
id: 5284607
db: PubChem-compound

3.4.21.38
type: BiochemicalReaction
participant stoichiometry: Protein/20356/Stoichiometry/1.0
right: Coagulation factor XI
spontaneous: false
EC number: 3.4.21.38
left: Coagulation factor XI
name: Coagulation factor XI → Coagulation factor XIa
conversion direction: LEFT_TO_RIGHT

Unknown
type: Protein
cellular location: Extracellular Space
entity reference: Unknown

3.4.21.27
type: BiochemicalReaction
participant stoichiometry: Protein/20358 Extracellular Space/Stoichiometry/1.0
right: Coagulation factor IX
spontaneous: false
EC number: 3.4.21.27
left: Coagulation factor IX
name: Coagulation factor IX → Coagulation factor IXa
conversion direction: LEFT_TO_RIGHT

3.4.21.5
type: BiochemicalReaction
participant stoichiometry: Protein/20361 Extracellular Space/Stoichiometry/1.0
right: Coagulation factor VIII
spontaneous: false
EC number: 3.4.21.5
left: Coagulation factor VIII
name: Coagulation factor VIII → Coagulation factor VIIIa
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 82688
type: UnificationXref
id: 82688
db: ChemSpider

ReactionCatalysis168904
type: Catalysis
controller: Vitamin K-dependent gamma-carboxylase
controlled: 4.1.1.90
control type: ACTIVATION

ReactionCatalysis168903
type: Catalysis
controller: Vitamin K-dependent gamma-carboxylase
controlled: 4.1.1.90
control type: ACTIVATION

ReactionCatalysis168902
type: Catalysis
controller: Vitamin K epoxide reductase complex subunit 1-like protein 1
controlled: 1.1.4.1
control type: ACTIVATION

ReactionCatalysis168901
type: Catalysis
controller: Tissue-type plasminogen activator
controlled: 3.4.21.68
control type: ACTIVATION

Coagulation factor XIII A chain
type: Protein
cellular location: Extracellular Space
entity reference: Coagulation factor XIII A chain

ReactionCatalysis168900
type: Catalysis
controller: Plasminogen
controlled: 3.4.21.7
control type: ACTIVATION

Reference/ChemSpider 4447652
type: UnificationXref
id: 4447652
db: ChemSpider

ProteinComplex/11585 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fibrinogen
stoichiometric coefficient: 1.0

Collagen alpha-1(I) chain
type: Protein
cellular location: Extracellular Space
entity reference: Collagen alpha-1(I) chain
name: SubPathwayActivator

Reference/KEGG Compound C05850
type: UnificationXref
id: C05850
db: KEGG Compound

SubPathwayControl109287
type: Interaction
name: SubPathway109287Control
name: ActivatingSubPathwayControl
participant: Activate Coagulatin factor VII to VIIa by binding to Tissue Factor
participant: Tissue factor
participant: Tissue factor:Coagulation factor VIIa
participant: Coagulation factor VII

Fibrinogen alpha chain
type: ProteinReference
xref: Reference/UniProt Q99K47
organism: Mus musculus

Prothrombin and coagulation factors VII, IX and X
type: Protein
entity reference: Prothrombin and coagulation factors VII, IX and X

Reference/BRENDA TISSUE ONTOLOGY BTO 0001102
type: UnificationXref
id: BTO:0001102
db: BRENDA TISSUE ONTOLOGY

Plasminogen
type: Protein
cellular location: Extracellular Space
entity reference: Plasminogen

Protein/20361 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coagulation factor VIII
stoichiometric coefficient: 1.0

SubPathwayControl109283
type: Interaction
name: SubPathway109283Control
name: ActivatingSubPathwayControl
participant: XII activated to XIIa by Collagen
participant: Coagulation factor XII
participant: Collagen alpha-1(I) chain

Fibrinogen beta chain
type: ProteinReference
xref: Reference/UniProt Q91ZP1
organism: Mus musculus

Reference/UniProt P20352
type: UnificationXref
id: P20352
db: UniProt

SubPathwayControl109284
type: Interaction
name: ActivatingSubPathwayControl
name: SubPathway109284Control
participant: XII activated to XIIa by Plasma kallikrein
participant: Plasma kallikrein
participant: Coagulation factor XII

ChemicalStructure/PW C002089
type: ChemicalStructure
structure format: SMILES

Protein/Generic45/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prothrombin and coagulation factors VII, IX and X
stoichiometric coefficient: 1.0

SubPathwayControl109285
type: Interaction
name: ActivatingSubPathwayControl
name: SubPathway109285Control
participant: Plasma prekallikrein activated to Plasma kallikrein by XIIa
participant: Plasma kallikrein
participant: Coagulation factor XII

SubPathwayControl109286
type: Interaction
name: SubPathway109286Control
name: ActivatingSubPathwayControl
participant: Coagulation factor XIII A and B activate to Coagulation factor XIIIa
participant: Coagulation factor XIII A chain
participant: Coagulation factor XIIIa
participant: Coagulation factor XIII B chain

Coagulation factor XI
type: Protein
cellular location: Extracellular Space
entity reference: Coagulation factor XI

Reference/TAXONOMY 10090
type: UnificationXref
id: 10090
db: TAXONOMY

Reference/BRENDA TISSUE ONTOLOGY BTO 0000759
type: UnificationXref
id: BTO:0000759
db: BRENDA TISSUE ONTOLOGY

Coagulation factor XIIIa
type: Complex
cellular location: Extracellular Space
component: Coagulation factor XIII A chain
component: Coagulation factor XIII B chain

Fibrin (loose)
type: Complex
cellular location: Extracellular Space
component: Fibrinogen beta chain
component: Fibrinogen alpha chain
component: Fibrinogen gamma chain

Reference/UniProt Q810J9
type: UnificationXref
id: Q810J9
db: UniProt

Coagulation factor XIIIa
type: Complex
component: Coagulation factor XIII A chain
component: Coagulation factor XIII B chain
name: SubPathwayActivation

BiologicalState326
type: BioSource
xref: Reference/TAXONOMY 10090
name: Mus musculus, Blood Vessel
tissue: Blood Vessel

Reference/UniProt Q3UV80
type: UnificationXref
id: Q3UV80
db: UniProt

Fibrinogen
type: Complex
cellular location: Extracellular Space
component: Fibrinogen beta chain
component: Fibrinogen alpha chain
component: Fibrinogen gamma chain

Coagulation factor XIII A chain
type: ProteinReference
xref: Reference/UniProt Q8BIP2
organism: Mus musculus

Fibrinogen gamma chain
type: ProteinReference
xref: Reference/UniProt Q91ZP0
organism: Mus musculus

Reference/HMDB HMDB0002972
type: UnificationXref
id: HMDB0002972
db: HMDB

Coagulation factor XIII B chain
type: ProteinReference
xref: Reference/UniProt B1AY02
organism: Mus musculus

Reference/UniProt A2AN88
type: UnificationXref
id: A2AN88
db: UniProt

Reference/HMDB HMDB0004198
type: UnificationXref
id: HMDB0004198
db: HMDB

Reference/SMPDB SMP0119368
type: UnificationXref
id: SMP0119368
db: SMPDB

Coagulation factor VII
type: Protein
entity reference: Coagulation factor VII
name: SubPathwayActivator

Protein/20367/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coagulation factor X
stoichiometric coefficient: 1.0

Coagulation factor V
type: Protein
cellular location: Extracellular Space
entity reference: Coagulation factor V

Protein/7736 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Fibrin (mesh)
type: Complex
cellular location: Extracellular Space
component: Fibrinogen beta chain
component: Fibrinogen alpha chain
component: Fibrinogen gamma chain

3.4.21.5
type: BiochemicalReaction
participant stoichiometry: Protein/20366 Extracellular Space/Stoichiometry/1.0
right: Coagulation factor V
spontaneous: false
EC number: 3.4.21.5
left: Coagulation factor V
name: Coagulation factor V → Coagulation factor Va
conversion direction: LEFT_TO_RIGHT

Fibrinogen beta chain
type: Protein
cellular location: Extracellular Space
entity reference: Fibrinogen beta chain

3.4.21.5
type: BiochemicalReaction
participant stoichiometry: ProteinComplex/11586 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: ProteinComplex/11585 Extracellular Space/Stoichiometry/1.0
right: Fibrin (loose)
spontaneous: false
EC number: 3.4.21.5
left: Fibrinogen
name: Fibrinogen → Fibrin (loose)
conversion direction: LEFT_TO_RIGHT

2.3.2.13
type: BiochemicalReaction
participant stoichiometry: ProteinComplex/11586 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: ProteinComplex/11587 Extracellular Space/Stoichiometry/1.0
right: Fibrin (mesh)
spontaneous: false
EC number: 2.3.2.13
left: Fibrin (loose)
name: Fibrin (loose) → Fibrin (mesh)
conversion direction: LEFT_TO_RIGHT

Tissue factor:Coagulation factor VIIa
type: Complex
component: Tissue factor
component: Coagulation factor VII
name: SubPathwayActivation

Reference/UniProt Q8R0P5
type: UnificationXref
id: Q8R0P5
db: UniProt

3.4.21.22
type: BiochemicalReaction
participant stoichiometry: Protein/20367 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Protein/20367/Stoichiometry/1.0
right: Coagulation factor X
spontaneous: false
EC number: 3.4.21.22
left: Coagulation factor X
name: Coagulation factor X → Coagulation factor Xa
conversion direction: LEFT_TO_RIGHT

Reaction178822
type: BiochemicalReaction
participant stoichiometry: Protein/13991 Extracellular Space/Stoichiometry/1.0
right: Prothrombin
spontaneous: false
left: Prothrombin
name: Prothrombin → Thrombin
conversion direction: LEFT_TO_RIGHT

Prothrombin
type: Protein
cellular location: Extracellular Space
entity reference: Prothrombin

Reference/UniProt Q99L32
type: UnificationXref
id: Q99L32
db: UniProt

Reference/BioCyc 23-EPOXY-23-DIHYDRO-2-METHYL-14-NAPHTHOQ
type: UnificationXref
id: 23-EPOXY-23-DIHYDRO-2-METHYL-14-NAPHTHOQ
db: BioCyc

Reference/UniProt Q6TEK5
type: UnificationXref
id: Q6TEK5
db: UniProt

Vitamin K1 2,3-epoxide
type: SmallMoleculeReference
xref: Reference/ChemSpider 82688
xref: Reference/HMDB HMDB0002972
xref: Reference/CAS 25486-55-9
xref: Reference/PubChem-compound 91577
xref: Reference/KEGG Compound C05849
xref: Reference/ChEBI CHEBI 28371
xref: Reference/BioCyc 23-EPOXY-23-DIHYDRO-2-METHYL-14-NAPHTHOQ
chemical formula: C31H46O3
molecular weight: 466.3447
structure: ChemicalStructure/PW C001746

BiologicalState336
type: BioSource
xref: Reference/TAXONOMY 10090
name: Mus musculus, Liver
tissue: Liver

ProteinComplex/11588 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fibrin degradation products
stoichiometric coefficient: 1.0

Coagulation factor IX
type: Protein
cellular location: Extracellular Space
entity reference: Coagulation factor IX

Coagulation factor XIII A and B activate to Coagulation factor XIIIa
type: Pathway
name: ActivatingSubPathway

Activate Coagulatin factor VII to VIIa by binding to Tissue Factor
type: Pathway
name: ActivatingSubPathway

Vitamin K-dependent gamma-carboxylase
type: Protein
cellular location: Extracellular Space
entity reference: Vitamin K-dependent gamma-carboxylase

XII activated to XIIa by Plasma kallikrein
type: Pathway
name: ActivatingSubPathway

Plasma prekallikrein activated to Plasma kallikrein by XIIa
type: Pathway
name: ActivatingSubPathway

Coagulation factor VII
type: ProteinReference
xref: Reference/UniProt Q61109

XII activated to XIIa by Collagen
type: Pathway
name: ActivatingSubPathway

Tissue-type plasminogen activator
type: ProteinReference
xref: Reference/UniProt Q91VP2
organism: Mus musculus

1.1.4.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002089/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001746/Stoichiometry/1.0
right: Reduced Vitamin K (phylloquinone)
spontaneous: false
EC number: 1.1.4.1
left: Vitamin K1 2,3-epoxide
name: Vitamin K1 2,3-epoxide → Reduced Vitamin K (phylloquinone)
conversion direction: LEFT_TO_RIGHT

4.1.1.90
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002089/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001746/Stoichiometry/1.0
right: Vitamin K1 2,3-epoxide
spontaneous: false
EC number: 4.1.1.90
left: Reduced Vitamin K (phylloquinone)
name: Reduced Vitamin K (phylloquinone) → Vitamin K1 2,3-epoxide
conversion direction: LEFT_TO_RIGHT

Coagulation factor X
type: Protein
cellular location: Extracellular Space
entity reference: Coagulation factor X

Reference/UniProt Q91WJ5
type: UnificationXref
id: Q91WJ5
db: UniProt

3.4.21.7
type: BiochemicalReaction
participant stoichiometry: ProteinComplex/11587 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: ProteinComplex/11588 Extracellular Space/Stoichiometry/1.0
right: Fibrin degradation products
spontaneous: false
EC number: 3.4.21.7
left: Fibrin (mesh)
name: Fibrin (mesh) → Fibrin degradation products
conversion direction: LEFT_TO_RIGHT

Precursors of Prothrombin and coagulation factors VII, IX, ad X
type: Protein
cellular location: Extracellular Space
entity reference: Precursors of Prothrombin and coagulation factors VII, IX, ad X

Coagulation factor XIII A chain
type: Protein
entity reference: Coagulation factor XIII A chain
name: SubPathwayActivator

Reference/PathWhiz PW120591
type: UnificationXref
id: PW120591
db: PathWhiz

Mus musculus
type: BioSource
xref: Reference/TAXONOMY 10090

3.4.21.68
type: BiochemicalReaction
participant stoichiometry: Protein/20390 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Protein/7736 Extracellular Space/Stoichiometry/1.0
right: Plasminogen
spontaneous: false
EC number: 3.4.21.68
left: Unknown
name: Plasminogen → Plasmin
conversion direction: LEFT_TO_RIGHT

Protein/20366 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coagulation factor V
stoichiometric coefficient: 1.0

Plasminogen
type: ProteinReference
xref: Reference/UniProt Q91WJ5
organism: Mus musculus

Reference/UniProt Q91ZP1
type: UnificationXref
id: Q91ZP1
db: UniProt

Protein/13991 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prothrombin
stoichiometric coefficient: 1.0

4.1.1.90
type: BiochemicalReaction
participant stoichiometry: Protein/Generic45 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Protein/Generic44 Extracellular Space/Stoichiometry/1.0
right: Prothrombin and coagulation factors VII, IX and X
spontaneous: false
EC number: 4.1.1.90
left: Precursors of Prothrombin and coagulation factors VII, IX, ad X
name: Precursors of Prothrombin and coagulation factors VII, IX, ad X → Prothrombin and coagulation factors VII, IX and X
conversion direction: LEFT_TO_RIGHT

Coagulation factor XIII B chain
type: Protein
entity reference: Coagulation factor XIII B chain
name: SubPathwayActivator

Prothrombin
type: ProteinReference
xref: Reference/UniProt P19221
organism: Mus musculus

Prothrombin and coagulation factors VII, IX and X
type: Protein
cellular location: Extracellular Space
entity reference: Prothrombin and coagulation factors VII, IX and X

Reference/UniProt Q6PER0
type: UnificationXref
id: Q6PER0
db: UniProt

Unknown
type: ProteinReference
organism: Mus musculus

Plasma kallikrein
type: Protein
cellular location: Extracellular Space
entity reference: Plasma kallikrein
name: SubPathwayActivator

Vitamin K1 2,3-epoxide
type: SmallMolecule
entity reference: Vitamin K1 2,3-epoxide

Coagulation factor XII
type: Protein
cellular location: Extracellular Space
entity reference: Coagulation factor XII
name: SubPathwayActivation
name: SubPathwayActivator

Coagulation factor XIII B chain
type: Protein
cellular location: Extracellular Space
entity reference: Coagulation factor XIII B chain

Tissue-type plasminogen activator
type: Protein
cellular location: Extracellular Space
entity reference: Tissue-type plasminogen activator

Reference/CAS 84-80-0
type: UnificationXref
id: 84-80-0
db: CAS

Protein/Generic44 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Precursors of Prothrombin and coagulation factors VII, IX, ad X
stoichiometric coefficient: 1.0

Fibrin degradation products
type: Complex
cellular location: Extracellular Space
component: Fibrinogen beta chain
component: Fibrinogen alpha chain
component: Fibrinogen gamma chain

Reference/UniProt Q9QYC7
type: UnificationXref
id: Q9QYC7
db: UniProt

Reference/PubChem-compound 91577
type: UnificationXref
id: 91577
db: PubChem-compound

ChemicalStructure/PW C001746
type: ChemicalStructure
structure format: SMILES

Precursors of Prothrombin and coagulation factors VII, IX, ad X
type: ProteinReference
xref: Reference/UniProt P00734
organism: Mus musculus

ProteinComplex/11587 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fibrin (mesh)
stoichiometric coefficient: 1.0

Prothrombin and coagulation factors VII, IX and X
type: ProteinReference
xref: Reference/UniProt P00734
organism: Mus musculus

Liver
type: TissueVocabulary
xref: Reference/BRENDA TISSUE ONTOLOGY BTO 0000759

Tissue factor
type: Protein
entity reference: Tissue factor
name: SubPathwayActivator

Coagulation factor X
type: Protein
entity reference: Coagulation factor X

Reference/CAS 25486-55-9
type: UnificationXref
id: 25486-55-9
db: CAS

Protein/20367 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coagulation factor X
stoichiometric coefficient: 1.0

Reference/UniProt Q9DAT3
type: UnificationXref
id: Q9DAT3
db: UniProt

Transport10070
type: Transport
participant stoichiometry: Protein/Generic45/Stoichiometry/1.0
right: Prothrombin and coagulation factors VII, IX and X
spontaneous: false
left: Prothrombin and coagulation factors VII, IX and X
name: Prothrombin and coagulation factors VII, IX and X (→) Transport: Mus musculus, Liver, Cell to Mus musculus, Blood Vessel
conversion direction: LEFT_TO_RIGHT

Vitamin K-dependent gamma-carboxylase
type: ProteinReference
xref: Reference/UniProt Q9QYC7

Vitamin K epoxide reductase complex subunit 1-like protein 1
type: ProteinReference
xref: Reference/UniProt Q6TEK5

ReactionCatalysis168899
type: Catalysis
controller: Coagulation factor XIIIa
controlled: 2.3.2.13
control type: ACTIVATION

ReactionCatalysis168898
type: Catalysis
controller: Prothrombin
controlled: 3.4.21.5
control type: ACTIVATION

ReactionCatalysis168896
type: Catalysis
controller: Tissue factor:Coagulation factor VIIa
controlled: 3.4.21.22
control type: ACTIVATION

Collagen alpha-1(I) chain
type: ProteinReference
xref: Reference/UniProt Q810J9
organism: Mus musculus

ReactionCatalysis168895
type: Catalysis
controller: Tenase complex
controlled: 3.4.21.22
control type: ACTIVATION

ReactionCatalysis168894
type: Catalysis
controller: Prothrombin
controlled: 3.4.21.5
control type: ACTIVATION

Reference/UniProt Q99K47
type: UnificationXref
id: Q99K47
db: UniProt

ReactionCatalysis168893
type: Catalysis
controller: Prothrombin
controlled: 3.4.21.5
control type: ACTIVATION

ReactionCatalysis168892
type: Catalysis
controller: Coagulation factor XI
controlled: 3.4.21.27
control type: ACTIVATION

ReactionCatalysis168891
type: Catalysis
controller: Coagulation factor XII
controlled: 3.4.21.38
control type: ACTIVATION

Extracellular Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005615

Coagulation factor XI
type: Protein
entity reference: Coagulation factor XI

Blood Vessel
type: TissueVocabulary
xref: Reference/BRENDA TISSUE ONTOLOGY BTO 0001102

Protein/Generic45 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prothrombin and coagulation factors VII, IX and X
stoichiometric coefficient: 1.0

Coagulation factor XII
type: ProteinReference
xref: Reference/UniProt Q6PER0

Reference/UniProt P19221
type: UnificationXref
id: P19221
db: UniProt

Coagulation factor VIII
type: Protein
cellular location: Extracellular Space
entity reference: Coagulation factor VIII

Reference/UniProt P00734
type: UnificationXref
id: P00734
db: UniProt

Plasma kallikrein
type: Protein
entity reference: Plasma kallikrein
name: SubPathwayActivation

Fibrinogen alpha chain
type: Protein
cellular location: Extracellular Space
entity reference: Fibrinogen alpha chain

ProteinComplex/11586 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fibrin (loose)
stoichiometric coefficient: 1.0

Reference/UniProt Q3UES1
type: UnificationXref
id: Q3UES1
db: UniProt

Coagulation factor IX
type: ProteinReference
xref: Reference/UniProt Q3UES1
organism: Mus musculus

Vitamin K-dependent gamma-carboxylase
type: Protein
entity reference: Vitamin K-dependent gamma-carboxylase

Vitamin K epoxide reductase complex subunit 1-like protein 1
type: Protein
entity reference: Vitamin K epoxide reductase complex subunit 1-like protein 1

Coagulation factor XI
type: ProteinReference
xref: Reference/UniProt Q9DAT3

Reference/UniProt Q61109
type: UnificationXref
id: Q61109
db: UniProt

Reference/ChEBI CHEBI 18067
type: UnificationXref
id: CHEBI:18067
db: ChEBI

Reduced Vitamin K (phylloquinone)
type: SmallMolecule
entity reference: Reduced Vitamin K (phylloquinone)

Reduced Vitamin K (phylloquinone)
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5284607
xref: Reference/ChemSpider 4447652
xref: Reference/HMDB HMDB0004198
xref: Reference/KEGG Compound C05850
xref: Reference/ChEBI CHEBI 18067
xref: Reference/CAS 84-80-0
chemical formula: C31H46O2
molecular weight: 450.3498
structure: ChemicalStructure/PW C002089

Reference/GENE ONTOLOGY GO 0005615
type: UnificationXref
id: GO:0005615
db: GENE ONTOLOGY

Protein/20358 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coagulation factor IX
stoichiometric coefficient: 1.0

Plasma kallikrein
type: ProteinReference
xref: Reference/UniProt Q8R0P5
organism: Mus musculus

Compound/PW C001746/Stoichiometry/1.0
type: Stoichiometry
physical entity: Vitamin K1 2,3-epoxide
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 28371
type: UnificationXref
id: CHEBI:28371
db: ChEBI

Coagulation
type: Pathway
pathway order: PathwayEnzymeReaction/2118878
pathway order: PathwayEnzymeReaction/2118877
pathway order: PathwayEnzymeReaction/2118888
pathway order: PathwaySubPathway/109287
pathway order: PathwayEnzymeReaction/2118879
pathway order: PathwayEnzymeReaction/2118885
pathway order: PathwaySubPathway/109284
pathway order: PathwayEnzymeReaction/2118884
pathway order: PathwaySubPathway/109283
pathway order: PathwayEnzymeReaction/2118876
pathway order: PathwayEnzymeReaction/2118887
pathway order: PathwaySubPathway/109286
pathway order: PathwayEnzymeReaction/2118875
pathway order: PathwayEnzymeReaction/2118886
pathway order: PathwaySubPathway/109285
pathway order: PathwayTransport/2118889
pathway order: PathwayEnzymeReaction/2118881
pathway order: PathwayEnzymeReaction/2118880
pathway order: PathwayEnzymeReaction/2118883
pathway order: PathwayEnzymeReaction/2118882
pathway component: ReactionCatalysis168899
pathway component: ReactionCatalysis168898
pathway component: ReactionCatalysis168896
pathway component: ReactionCatalysis168895
pathway component: ReactionCatalysis168894
pathway component: ReactionCatalysis168893
pathway component: ReactionCatalysis168892
pathway component: ReactionCatalysis168891
pathway component: 3.4.21.38
pathway component: 3.4.21.27
pathway component: 3.4.21.5
pathway component: ReactionCatalysis168904
pathway component: ReactionCatalysis168903
pathway component: ReactionCatalysis168902
pathway component: ReactionCatalysis168901
pathway component: ReactionCatalysis168900
pathway component: 2.3.2.13
pathway component: 3.4.21.22
pathway component: Reaction178822
pathway component: SubPathwayControl109287
pathway component: SubPathwayControl109283
pathway component: SubPathwayControl109284
pathway component: SubPathwayControl109285
pathway component: SubPathwayControl109286
pathway component: 1.1.4.1
pathway component: 4.1.1.90
pathway component: 3.4.21.7
pathway component: 3.4.21.68
pathway component: Transport10070
xref: Reference/SMPDB SMP0119368
xref: Reference/PathWhiz PW120591
organism: Mus musculus

Coagulation factor XII
type: Protein
entity reference: Coagulation factor XII