Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/UniProt Q2KI20
type: UnificationXref
id: Q2KI20
db: UniProt

ChemicalStructure/PW C000693
type: ChemicalStructure
structure format: SMILES
structure data: NCCC1=CNC=N1

Reference/HMDB HMDB0000895
type: UnificationXref
id: HMDB0000895
db: HMDB

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Gastrin
type: Protein
cellular location: Cell Membrane
entity reference: Gastrin
name: SubPathwayActivator

Reference/TAXONOMY 9913
type: UnificationXref
id: 9913
db: TAXONOMY

Acetylcholine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15355
xref: Reference/CAS 51-84-3
xref: Reference/HMDB HMDB0000895
xref: Reference/ChemSpider 182
xref: Reference/KEGG Compound C01996
xref: Reference/BioCyc ACETYLCHOLINE
xref: Reference/PubChem-compound 187
chemical formula: C7H16NO2
molecular weight: 146.1181
structure: ChemicalStructure/PW C000714

TransportCatalysis1332
type: Catalysis
controller: Sulfate transporter
controlled: Transport10117
control type: ACTIVATION

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

ChemicalStructure/PW C000457
type: ChemicalStructure
structure format: SMILES
structure data: [K+]

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

ChemicalStructure/PW C000463
type: ChemicalStructure
structure format: SMILES
structure data: OC([O-])=O

3.6.3.10
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000457 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cell Membrane/Stoichiometry/1.0
right: Adenosine diphosphate
right: Phosphate
right: Hydrogen Ion
right: Potassium
spontaneous: false
EC number: 3.6.3.10
left: Hydrogen Ion
left: Adenosine triphosphate
left: Water
left: Potassium
name: Adenosine triphosphate + Hydrogen Ion + Potassium + Water → Adenosine diphosphate + Hydrogen Ion + Phosphate + Potassium
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Sulfate transporter
type: Protein
entity reference: Sulfate transporter

Reference/PathWhiz PW000728
type: UnificationXref
id: PW000728
db: PathWhiz

Reference/BioCyc HCO3
type: UnificationXref
id: HCO3
db: BioCyc

Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/KEGG Compound C00698
type: UnificationXref
id: C00698
db: KEGG Compound

Acetylcholine
type: SmallMolecule
entity reference: Acetylcholine
name: SubPathwayActivator

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Compound/PW C000457 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Potassium
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Carbon dioxide

Chloride intracellular channel protein 4
type: Protein
entity reference: Chloride intracellular channel protein 4

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/UniProt Q3ZBJ4
type: UnificationXref
id: Q3ZBJ4
db: UniProt

Chloride ion
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17996
xref: Reference/BioCyc CPD-4521
xref: Reference/PubChem-compound 312
xref: Reference/KEGG Compound C00698
xref: Reference/HMDB HMDB0000492
xref: Reference/ChemSpider 306
xref: Reference/CAS 16887-00-6
chemical formula: Cl
molecular weight: 34.968853
structure: ChemicalStructure/PW C000374

Reference/BioCyc ACETYLCHOLINE
type: UnificationXref
id: ACETYLCHOLINE
db: BioCyc

Phosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Phosphate

Compound/PW C000463 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen carbonate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 813
type: UnificationXref
id: 813
db: PubChem-compound

Compound/PW C000374 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chloride ion
stoichiometric coefficient: 1.0

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

Compound/PW C001034 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/KEGG Compound C00238
type: UnificationXref
id: C00238
db: KEGG Compound

4.2.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000463 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytoplasm/Stoichiometry/1.0
right: Hydrogen Ion
right: Hydrogen carbonate
spontaneous: false
EC number: 4.2.1.1
left: Carbon dioxide
left: Water
name: Carbon dioxide + Water → Hydrogen Ion + Hydrogen carbonate
conversion direction: LEFT_TO_RIGHT

Compound/PW C040034 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C000374 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chloride ion
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Hydrogen Ion

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

ChemicalStructure/PW C000374
type: ChemicalStructure
structure format: SMILES
structure data: [Cl-]

Somatostatin receptor type 5
type: Protein
entity reference: Somatostatin receptor type 5
name: SubPathwayInhibition
name: SubPathwayInput

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Sulfate transporter
type: ProteinReference
xref: Reference/UniProt Q9BEG8

Chloride ion
type: SmallMolecule
cellular location: Extracellular Space
entity reference: Chloride ion

Reference/GENE ONTOLOGY GO 0005886
type: UnificationXref
id: GO:0005886
db: GENE ONTOLOGY

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/UniProt Q3Y5Z2
type: UnificationXref
id: Q3Y5Z2
db: UniProt

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/PubChem-compound 312
type: UnificationXref
id: 312
db: PubChem-compound

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/CAS 24203-36-9
type: UnificationXref
id: 24203-36-9
db: CAS

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Transport10117
type: Transport
participant stoichiometry: Compound/PW C000374 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000463 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000374 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000463 Extracellular Space/Stoichiometry/1.0
right: Hydrogen carbonate
right: Chloride ion
spontaneous: false
left: Hydrogen carbonate
left: Chloride ion
name: Chloride ion (→), Hydrogen carbonate (←) Transport: Bos taurus, Extracellular Space to Bos taurus, Cell, Cytoplasm
conversion direction: LEFT_TO_RIGHT

Carbonic anhydrase 1
type: ProteinReference
xref: Reference/UniProt Q1LZA1
organism: Bos taurus

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Somatostatin
type: Protein
entity reference: Somatostatin
name: SubPathwayInhibitor

Reference/HMDB HMDB0000586
type: UnificationXref
id: HMDB0000586
db: HMDB

Reference/UniProt Q1LZA1
type: UnificationXref
id: Q1LZA1
db: UniProt

Potassium
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Potassium

TransportCatalysis1300
type: Catalysis
controller: Chloride intracellular channel protein 4
controlled: Transport10087
control type: ACTIVATION

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Extracellular Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005615

Reference/HMDB HMDB0000595
type: UnificationXref
id: HMDB0000595
db: HMDB

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

SubPathwayControl109336
type: Interaction
name: SubPathway109336Control
name: ActivatingSubPathwayControl
participant: Unknown
participant: Histamine Activation of Histamine H2 Receptor
participant: Histamine

SubPathwayControl109337
type: Interaction
name: ActivatingSubPathwayControl
name: SubPathway109337Control
participant: Gastrin
participant: Gastrin Activation of Gastrin/cholecystokinin type B receptor
participant: Gastrin/cholecystokinin type B receptor

SubPathwayControl109338
type: Interaction
name: SubPathway109338Control
name: ActivatingSubPathwayControl
participant: Gastric H(+)/K(+) ATPase subunit
participant: Gastrin/cholecystokinin type B receptor
participant: G-Protein Signaling Cascade

ReactionCatalysis168926
type: Catalysis
controller: Carbonic anhydrase 1
controlled: 4.2.1.1
control type: ACTIVATION

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Gastric H(+)/K(+) ATPase subunit
type: Complex
component stoichiometry: Protein/7764 Cell Membrane/Stoichiometry/1.0
cellular location: Cell Membrane
component: Unknown
name: SubPathwayOutput

Reference/KEGG Compound C00388
type: UnificationXref
id: C00388
db: KEGG Compound

SubPathwayControl109342
type: Interaction
name: SubPathway109342Control
name: ActivatingSubPathwayControl
participant: Acetylcholine activation of Muscarinic acetylcholine receptor M3
participant: Unknown
participant: Acetylcholine

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005615
type: UnificationXref
id: GO:0005615
db: GENE ONTOLOGY

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Gastrin/cholecystokinin type B receptor
type: Protein
entity reference: Gastrin/cholecystokinin type B receptor
name: SubPathwayActivator

SubPathwayControl109340
type: Interaction
name: SubPathway109340Control
name: InhibitorySubPathwayControl
participant: Somatostatin
participant: Somatostatin inhibition of Somatostatin receptor type 4
participant: Somatostatin receptor type 5

Reference/SMPDB SMP0000751
type: UnificationXref
id: SMP0000751
db: SMPDB

Protein/7764/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 29103
type: UnificationXref
id: CHEBI:29103
db: ChEBI

Reference/PubChem-compound 769
type: UnificationXref
id: 769
db: PubChem-compound

Somatostatin
type: ProteinReference
xref: Reference/UniProt Q3Y5Z2

Protein/7764 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/CAS 51-45-6
type: UnificationXref
id: 51-45-6
db: CAS

Compound/PW C001316 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/UniProt F1MV99
type: UnificationXref
id: F1MV99
db: UniProt

SubPathwayInteraction109335
type: Interaction
name: SubPathway109335Reaction
name: SubPathwayReaction
participant: Unknown
participant: Gastric H(+)/K(+) ATPase subunit

Adenosine triphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Adenosine triphosphate

Reference/HMDB HMDB0000492
type: UnificationXref
id: HMDB0000492
db: HMDB

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/ChEBI CHEBI 17996
type: UnificationXref
id: CHEBI:17996
db: ChEBI

Somatostatin receptor type 5
type: ProteinReference
xref: Reference/UniProt F1MV99

ReactionCoupledTransportCatalysis460
type: Catalysis
controller: Gastric H(+)/K(+) ATPase subunit
controlled: 3.6.3.10
control type: ACTIVATION

Water
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Water

Reference/BioCyc K+
type: UnificationXref
id: K%2b
db: BioCyc

Reference/KEGG Compound C00288
type: UnificationXref
id: C00288
db: KEGG Compound

Reference/CAS 16887-00-6
type: UnificationXref
id: 16887-00-6
db: CAS

Gastrin/cholecystokinin type B receptor
type: Protein
cellular location: Cell Membrane
entity reference: Gastrin/cholecystokinin type B receptor
name: SubPathwayActivation

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Bos taurus
type: BioSource
xref: Reference/TAXONOMY 9913

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Reference/CAS 51-84-3
type: UnificationXref
id: 51-84-3
db: CAS

Hydrogen carbonate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Hydrogen carbonate

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Hydrogen Ion
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Hydrogen Ion

Compound/PW C000374 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chloride ion
stoichiometric coefficient: 1.0

Unknown
type: Protein
entity reference: Unknown
name: SubPathwayInput
name: SubPathwayActivation

Reference/ChemSpider 791
type: UnificationXref
id: 791
db: ChemSpider

Reference/SMPDB SMP0119381
type: UnificationXref
id: SMP0119381
db: SMPDB

Reference/PubChem-compound 774
type: UnificationXref
id: 774
db: PubChem-compound

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

SubPathwayInteraction109339
type: Interaction
name: SubPathwayReaction
name: SubPathway109339Reaction
participant: Somatostatin receptor type 5
participant: Gastric H(+)/K(+) ATPase subunit

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/ChemSpider 306
type: UnificationXref
id: 306
db: ChemSpider

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Chloride intracellular channel protein 4
type: ProteinReference
xref: Reference/UniProt Q3ZBJ4

ChemicalStructure/PW C000714
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)OCC[N+](C)(C)C

Compound/PW C040034 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/UniProt Q28114
type: UnificationXref
id: Q28114
db: UniProt

SubPathwayInteraction109341
type: Interaction
name: SubPathway109341Reaction
name: SubPathwayReaction
participant: Gastric H(+)/K(+) ATPase subunit
participant: Unknown

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChEBI CHEBI 17544
type: UnificationXref
id: CHEBI:17544
db: ChEBI

Gastric H(+)/K(+) ATPase subunit
type: Complex
component stoichiometry: Protein/7764/Stoichiometry/1.0
component: Unknown
name: SubPathwayOutput
name: SubPathwayActivation

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Unknown
type: Protein
cellular location: Cell Membrane
entity reference: Unknown
name: SubPathwayInput
name: SubPathwayActivation

Transport10087
type: Transport
participant stoichiometry: Compound/PW C000374 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000374 Cytosol/Stoichiometry/1.0
right: Chloride ion
spontaneous: false
left: Chloride ion
name: Chloride ion (→) Transport: Bos taurus, Cell, Cytosol to Bos taurus, Extracellular Space
conversion direction: LEFT_TO_RIGHT

Histamine
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Histamine
name: SubPathwayActivator

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Hydrogen carbonate
type: SmallMolecule
cellular location: Extracellular Space
entity reference: Hydrogen carbonate

G-Protein Signaling Cascade
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway109335
pathway order: SubPathwayInteractionSteps/SubPathway109339
pathway order: SubPathwayInteractionSteps/SubPathway109341
pathway component: SubPathwayInteraction109339
pathway component: SubPathwayInteraction109335
pathway component: SubPathwayInteraction109341
xref: Reference/SMPDB SMP0000751
xref: Reference/PathWhiz PW000728
name: SubPathway

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Cell Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005886

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Gastric Acid Production
type: Pathway
pathway order: PathwaySubPathway/109342
pathway order: PathwayTransport/2119004
pathway order: PathwayTransport/2119003
pathway order: PathwaySubPathway/109341
pathway order: PathwaySubPathway/109340
pathway order: PathwayEnzymeReaction/2119002
pathway order: PathwayEnzymeReaction/2119001
pathway order: PathwaySubPathway/109339
pathway order: PathwaySubPathway/109336
pathway order: PathwaySubPathway/109335
pathway order: PathwaySubPathway/109338
pathway order: PathwaySubPathway/109337
pathway component: ReactionCatalysis168926
pathway component: 4.2.1.1
pathway component: TransportCatalysis1300
pathway component: TransportCatalysis1332
pathway component: Transport10117
pathway component: ReactionCoupledTransportCatalysis460
pathway component: SubPathwayControl109342
pathway component: Transport10087
pathway component: SubPathwayControl109340
pathway component: 3.6.3.10
pathway component: SubPathwayControl109336
pathway component: G-Protein Signaling Cascade
pathway component: SubPathwayControl109337
pathway component: SubPathwayControl109338
xref: Reference/SMPDB SMP0119381
xref: Reference/PathWhiz PW120604
organism: Bos taurus

Reference/PathWhiz PW120604
type: UnificationXref
id: PW120604
db: PathWhiz

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Histamine Activation of Histamine H2 Receptor
type: Pathway
name: ActivatingSubPathway

Reference/BioCyc HISTAMINE
type: UnificationXref
id: HISTAMINE
db: BioCyc

Gastrin Activation of Gastrin/cholecystokinin type B receptor
type: Pathway
name: ActivatingSubPathway

Acetylcholine activation of Muscarinic acetylcholine receptor M3
type: Pathway
name: ActivatingSubPathway

Somatostatin inhibition of Somatostatin receptor type 4
type: Pathway
name: InhibitorySubPathway

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Chloride ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Chloride ion

Reference/BioCyc CPD-4521
type: UnificationXref
id: CPD-4521
db: BioCyc

Gastrin/cholecystokinin type B receptor
type: ProteinReference
xref: Reference/UniProt Q2KI20
organism: Bos taurus

Reference/ChEBI CHEBI 18295
type: UnificationXref
id: CHEBI:18295
db: ChEBI

Chloride ion
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Chloride ion

Gastrin
type: ProteinReference
xref: Reference/UniProt Q28114
organism: Bos taurus

Reference/PubChem-compound 187
type: UnificationXref
id: 187
db: PubChem-compound

Reference/HMDB HMDB0000870
type: UnificationXref
id: HMDB0000870
db: HMDB

Reference/ChemSpider 753
type: UnificationXref
id: 753
db: ChemSpider

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Histamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000870
xref: Reference/ChemSpider 753
xref: Reference/PubChem-compound 774
xref: Reference/BioCyc HISTAMINE
xref: Reference/CAS 51-45-6
xref: Reference/ChEBI CHEBI 18295
xref: Reference/KEGG Compound C00388
chemical formula: C5H9N3
molecular weight: 111.07965
structure: ChemicalStructure/PW C000693

Reference/ChEBI CHEBI 15355
type: UnificationXref
id: CHEBI:15355
db: ChEBI

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Potassium
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00238
xref: Reference/HMDB HMDB0000586
xref: Reference/PubChem-compound 813
xref: Reference/ChemSpider 791
xref: Reference/CAS 24203-36-9
xref: Reference/BioCyc K+
xref: Reference/ChEBI CHEBI 29103
chemical formula: K
molecular weight: 38.963707
structure: ChemicalStructure/PW C000457

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChemSpider 749
type: UnificationXref
id: 749
db: ChemSpider

Reference/CAS 71-52-3
type: UnificationXref
id: 71-52-3
db: CAS

Compound/PW C000463 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen carbonate
stoichiometric coefficient: 1.0

Unknown
type: ProteinReference
organism: Bos taurus

Reference/KEGG Compound C01996
type: UnificationXref
id: C01996
db: KEGG Compound

Reference/UniProt Q9BEG8
type: UnificationXref
id: Q9BEG8
db: UniProt

Adenosine diphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Adenosine diphosphate

Hydrogen carbonate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000595
xref: Reference/ChEBI CHEBI 17544
xref: Reference/PubChem-compound 769
xref: Reference/BioCyc HCO3
xref: Reference/ChemSpider 749
xref: Reference/CAS 71-52-3
xref: Reference/KEGG Compound C00288
chemical formula: CHO3
molecular weight: 60.99257
structure: ChemicalStructure/PW C000463

Reference/ChemSpider 182
type: UnificationXref
id: 182
db: ChemSpider

Carbonic anhydrase 1
type: Protein
cellular location: Cytoplasm
entity reference: Carbonic anhydrase 1