Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Protein/7725 Cytoplasm/Stoichiometry/6.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 6.0

ChemicalStructure/PW C000206
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Compound/PW C001207 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 1-phosphate
stoichiometric coefficient: 1.0

Unknown
type: Protein
cellular location: Cytoplasm
entity reference: Unknown

Reference/CAS 2956-16-3
type: UnificationXref
id: 2956-16-3
db: CAS

Reference/BioCyc UDP-GLACTOSE
type: UnificationXref
id: UDP-GLACTOSE
db: BioCyc

Reference/CAS 3616-06-6
type: UnificationXref
id: 3616-06-6
db: CAS

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/PubChem-compound 6133
type: UnificationXref
id: 6133
db: PubChem-compound

Reference/KEGG Compound C00446
type: UnificationXref
id: C00446
db: KEGG Compound

Glucose 1-phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Glucose 1-phosphate

Reference/CAS 2616-64-0
type: UnificationXref
id: 2616-64-0
db: CAS

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/ChemSpider 388480
type: UnificationXref
id: 388480
db: ChemSpider

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/BioCyc GALACTOSE-1P
type: UnificationXref
id: GALACTOSE-1P
db: BioCyc

Galactose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway107952
pathway component: SubPathwayInteraction107952
xref: Reference/PathWhiz PW000159
xref: Reference/SMPDB SMP0000043
name: SubPathway

Compound/PW C000805 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: UDP-D-Xylose
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

Reference/HMDB HMDB0000302
type: UnificationXref
id: HMDB0000302
db: HMDB

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway107951
pathway component: SubPathwayInteraction107951
xref: Reference/SMPDB SMP0000040
xref: Reference/PathWhiz PW000146
name: SubPathway

ReactionCatalysis100282
type: Catalysis
controller: Unknown
controlled: 5.4.2.2
control type: ACTIVATION

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/BioCyc UDP-D-XYLOSE
type: UnificationXref
id: UDP-D-XYLOSE
db: BioCyc

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/TAXONOMY 10090
type: UnificationXref
id: 10090
db: TAXONOMY

Reference/ChemSpider 5743
type: UnificationXref
id: 5743
db: ChemSpider

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/ChEBI CHEBI 17200
type: UnificationXref
id: CHEBI:17200
db: ChEBI

UDP-D-Xylose
type: SmallMoleculeReference
xref: Reference/CAS 3616-06-6
xref: Reference/KEGG Compound C00190
xref: Reference/PubChem-compound 439179
xref: Reference/ChemSpider 388324
xref: Reference/HMDB HMDB0001018
xref: Reference/ChEBI CHEBI 16082
xref: Reference/BioCyc UDP-D-XYLOSE
chemical formula: C14H22N2O16P2
molecular weight: 536.04443
structure: ChemicalStructure/PW C000805

Reference/PubChem-compound 439179
type: UnificationXref
id: 439179
db: PubChem-compound

Reference/HMDB HMDB0001401
type: UnificationXref
id: HMDB0001401
db: HMDB

Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
type: UnificationXref
id: ALPHA-GLUCOSE-16-BISPHOSPHATE
db: BioCyc

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Uridine diphosphate glucose
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Uridine diphosphate glucose

ChemicalStructure/PW C001083
type: ChemicalStructure
structure format: SMILES

D-Galactose
type: SmallMolecule
cellular location: Cytoplasm
entity reference: D-Galactose
name: SubPathwayInput

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/PubChem-compound 53477679
type: UnificationXref
id: 53477679
db: PubChem-compound

Reference/BioCyc UDP-GLUCURONATE
type: UnificationXref
id: UDP-GLUCURONATE
db: BioCyc

Reference/PathWhiz PW000159
type: UnificationXref
id: PW000159
db: PathWhiz

Reference/ChEBI CHEBI 15713
type: UnificationXref
id: CHEBI:15713
db: ChEBI

Reference/CAS 133-89-1
type: UnificationXref
id: 133-89-1
db: CAS

Reference/PathWhiz PW000152
type: UnificationXref
id: PW000152
db: PathWhiz

Reference/KEGG Compound C00103
type: UnificationXref
id: C00103
db: KEGG Compound

Reference/PubChem-compound 439165
type: UnificationXref
id: 439165
db: PubChem-compound

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Compound/PW C001083 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Mus musculus
type: BioSource
xref: Reference/TAXONOMY 10090

UTP--glucose-1-phosphate uridylyltransferase
type: Complex
component stoichiometry: Protein/7725 Cytoplasm/Stoichiometry/8.0
cellular location: Cytoplasm
component: Unknown

Uridine diphosphate glucuronic acid
type: SmallMoleculeReference
xref: Reference/BioCyc UDP-GLUCURONATE
xref: Reference/CAS 2616-64-0
xref: Reference/PubChem-compound 17473
xref: Reference/HMDB HMDB0000935
xref: Reference/ChEBI CHEBI 17200
xref: Reference/ChemSpider 16522
xref: Reference/KEGG Compound C00167
chemical formula: C15H22N2O18P2
molecular weight: 580.0343
structure: ChemicalStructure/PW C000746

Galactose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 110443
xref: Reference/KEGG Compound C00446
xref: Reference/ChEBI CHEBI 17973
xref: Reference/PubChem-compound 123912
xref: Reference/CAS 2255-14-3
xref: Reference/HMDB HMDB0000645
xref: Reference/BioCyc GALACTOSE-1P
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000504

ChemicalStructure/PW C000805
type: ChemicalStructure
structure format: SMILES

Reference/CAS 59-56-3
type: UnificationXref
id: 59-56-3
db: CAS

Reference/ChemSpider 388311
type: UnificationXref
id: 388311
db: ChemSpider

Compound/PW C000192 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine triphosphate
stoichiometric coefficient: 1.0

Uridine diphosphate glucose
type: SmallMoleculeReference
xref: Reference/BioCyc UDP-GLUCOSE
xref: Reference/KEGG Compound C00029
xref: Reference/PubChem-compound 53477679
xref: Reference/CAS 133-89-1
xref: Reference/HMDB HMDB0000286
chemical formula: C15H24N2O17P2
molecular weight: 566.055
structure: ChemicalStructure/PW C000193

Reference/BioCyc UDP-GLUCOSE
type: UnificationXref
id: UDP-GLUCOSE
db: BioCyc

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Uridine triphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6133
xref: Reference/CAS 63-39-8
xref: Reference/ChemSpider 5903
xref: Reference/ChEBI CHEBI 15713
xref: Reference/KEGG Compound C00075
xref: Reference/HMDB HMDB0000285
xref: Reference/BioCyc UTP
chemical formula: C9H15N2O15P3
molecular weight: 483.96854
structure: ChemicalStructure/PW C000192

Reference/SMPDB SMP0000040
type: UnificationXref
id: SMP0000040
db: SMPDB

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/SMPDB SMP0000043
type: UnificationXref
id: SMP0000043
db: SMPDB

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/ChEBI CHEBI 67119
type: UnificationXref
id: CHEBI:67119
db: ChEBI

Reference/ChemSpider 388324
type: UnificationXref
id: 388324
db: ChemSpider

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/PubChem-compound 17473
type: UnificationXref
id: 17473
db: PubChem-compound

α-D-Glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003345
xref: Reference/ChemSpider 71358
xref: Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
xref: Reference/PubChem-compound 79025
xref: Reference/ChEBI CHEBI 17925
xref: Reference/CAS 492-62-6
xref: Reference/KEGG Compound C00267
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C001851

Reference/BioCyc GLC-1-P
type: UnificationXref
id: GLC-1-P
db: BioCyc

Galactose 1-phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Galactose 1-phosphate

Gluconeogenesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway107950
pathway component: SubPathwayInteraction107950
xref: Reference/SMPDB SMP0000128
xref: Reference/PathWhiz PW000152
name: SubPathway

Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Galactokinase
type: Complex
component stoichiometry: Protein/7725 Cytoplasm/Stoichiometry/2.0
cellular location: Cytoplasm
component: Unknown

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine triphosphate

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/SMPDB SMP0120560
type: UnificationXref
id: SMP0120560
db: SMPDB

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

ReactionCatalysis100397
type: Catalysis
controller: UTP--glucose-1-phosphate uridylyltransferase
controlled: 2.7.7.9
control type: ACTIVATION

Reference/PubChem-compound 5958
type: UnificationXref
id: 5958
db: PubChem-compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

ReactionCatalysis100271
type: Catalysis
controller: Galactokinase
controlled: 2.7.1.6
control type: ACTIVATION

ReactionCatalysis100279
type: Catalysis
controller: Unknown
controlled: 2.7.1.2
control type: ACTIVATION

Compound/PW C000193 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucose
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00029
type: UnificationXref
id: C00029
db: KEGG Compound

Reference/CAS 59-23-4
type: UnificationXref
id: 59-23-4
db: CAS

ChemicalStructure/PW C001207
type: ChemicalStructure
structure format: SMILES

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00267
type: UnificationXref
id: C00267
db: KEGG Compound

Uridine triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Uridine triphosphate

2.7.7.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000192 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000193 Cytoplasm/Stoichiometry/1.0
right: Uridine diphosphate glucose
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.9
left: Uridine triphosphate
left: Glucose 1-phosphate
name: Glucose 1-phosphate + Uridine triphosphate → Pyrophosphate + Uridine diphosphate glucose
conversion direction: LEFT_TO_RIGHT

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

2.7.7.12
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000504 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000206 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000193 Cytoplasm/Stoichiometry/1.0
right: Galactose 1-phosphate
right: Uridine diphosphate glucose
spontaneous: false
EC number: 2.7.7.12
left: Glucose 1-phosphate
left: Uridine diphosphategalactose
name: Glucose 1-phosphate + Uridine diphosphategalactose ↔ Galactose 1-phosphate + Uridine diphosphate glucose
conversion direction: REVERSIBLE

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Compound/PW C001144 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 2.0

Uridine diphosphategalactose
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Uridine diphosphategalactose

Reference/ChEBI CHEBI 17925
type: UnificationXref
id: CHEBI:17925
db: ChEBI

Protein/7725 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Reference/SMPDB SMP0000128
type: UnificationXref
id: SMP0000128
db: SMPDB

Unknown
type: Protein
cellular location: Golgi apparatus
entity reference: Unknown

NADH
type: SmallMolecule
cellular location: Cytoplasm
entity reference: NADH

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Galactosemia II (GALK)
type: Pathway
pathway order: PathwayEnzymeReaction/2111020
pathway order: PathwayEnzymeReaction/2111022
pathway order: PathwayEnzymeReaction/2111021
pathway order: PathwayEnzymeReaction/2111024
pathway order: PathwayEnzymeReaction/2111023
pathway order: PathwayEnzymeReaction/2111026
pathway order: PathwayEnzymeReaction/2111025
pathway order: PathwayEnzymeReaction/2111027
pathway order: PathwaySubPathway/107950
pathway order: PathwaySubPathway/107951
pathway order: PathwaySubPathway/107952
pathway component: 5.4.2.2
pathway component: 2.7.1.6
pathway component: 2.7.7.9
pathway component: ReactionCatalysis100464
pathway component: ReactionCatalysis100397
pathway component: ReactionCatalysis100463
pathway component: Galactose Metabolism
pathway component: ReactionCatalysis100462
pathway component: 2.7.7.12
pathway component: 1.1.1.22
pathway component: Glycolysis
pathway component: 2.7.1.2
pathway component: ReactionCatalysis100282
pathway component: ReactionCatalysis100271
pathway component: 4.1.1.35
pathway component: Gluconeogenesis
pathway component: Reaction110156
pathway component: ReactionCatalysis100279
pathway component: ReactionCatalysis100400
xref: Reference/PathWhiz PW121816
xref: Reference/SMPDB SMP0120560
organism: Mus musculus

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/HMDB HMDB0001586
type: UnificationXref
id: HMDB0001586
db: HMDB

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

α-D-Glucose
type: SmallMolecule
cellular location: Cytoplasm
entity reference: α-D-Glucose
name: SubPathwayOutput
name: SubPathwayInput

Reference/PubChem-compound 123912
type: UnificationXref
id: 123912
db: PubChem-compound

Uridine diphosphate glucuronic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Uridine diphosphate glucuronic acid

Compound/PW C001316 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

SubPathwayInteraction107950
type: Interaction
name: SubPathway107950Reaction
name: SubPathwayReaction
participant: α-D-Glucose

SubPathwayInteraction107951
type: Interaction
name: SubPathway107951Reaction
name: SubPathwayReaction
participant: α-D-Glucose

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00092
xref: Reference/BioCyc GLC-6-P
xref: Reference/HMDB HMDB0001401
xref: Reference/PubChem-compound 5958
xref: Reference/ChemSpider 5743
xref: Reference/CAS 56-73-5
xref: Reference/ChEBI CHEBI 4170
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001083

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/HMDB HMDB0000935
type: UnificationXref
id: HMDB0000935
db: HMDB

Compound/PW C000206 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphategalactose
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00167
type: UnificationXref
id: C00167
db: KEGG Compound

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00052
type: UnificationXref
id: C00052
db: KEGG Compound

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Reference/GENE ONTOLOGY GO 0005794
type: UnificationXref
id: GO:0005794
db: GENE ONTOLOGY

Reference/HMDB HMDB0000143
type: UnificationXref
id: HMDB0000143
db: HMDB

Reference/BioCyc UTP
type: UnificationXref
id: UTP
db: BioCyc

Compound/PW C000504 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 5903
type: UnificationXref
id: 5903
db: ChemSpider

Reference/BioCyc GALACTOSE
type: UnificationXref
id: GALACTOSE
db: BioCyc

Reference/ChEBI CHEBI 28061
type: UnificationXref
id: CHEBI:28061
db: ChEBI

2.7.1.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000504 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000093 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
right: Galactose 1-phosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.6
left: Adenosine triphosphate
left: D-Galactose
name: Adenosine triphosphate + D-Galactose → Adenosine diphosphate + Galactose 1-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 18068
type: UnificationXref
id: 18068
db: PubChem-compound

Reference/ChEBI CHEBI 16077
type: UnificationXref
id: CHEBI:16077
db: ChEBI

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/ChEBI CHEBI 4170
type: UnificationXref
id: CHEBI:4170
db: ChEBI

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/ChemSpider 110443
type: UnificationXref
id: 110443
db: ChemSpider

D-Galactose
type: SmallMoleculeReference
xref: Reference/BioCyc GALACTOSE
xref: Reference/PubChem-compound 439357
xref: Reference/CAS 59-23-4
xref: Reference/ChEBI CHEBI 28061
xref: Reference/ChemSpider 388480
xref: Reference/KEGG Compound C00984
xref: Reference/HMDB HMDB0000143
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000093

2.7.1.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001851 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001083 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
right: Glucose 6-phosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.2
left: α-D-Glucose
left: Adenosine triphosphate
name: Adenosine triphosphate + α-D-Glucose → Adenosine diphosphate + Glucose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 492-62-6
type: UnificationXref
id: 492-62-6
db: CAS

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine diphosphate

Reference/ChemSpider 16522
type: UnificationXref
id: 16522
db: ChemSpider

Reference/ChEBI CHEBI 17973
type: UnificationXref
id: CHEBI:17973
db: ChEBI

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

SubPathwayInteraction107952
type: Interaction
name: SubPathway107952Reaction
name: SubPathwayReaction
participant: D-Galactose

Unknown
type: ProteinReference
organism: Mus musculus

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

5.4.2.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001083 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytoplasm/Stoichiometry/1.0
right: Glucose 6-phosphate
spontaneous: false
EC number: 5.4.2.2
left: Glucose 1-phosphate
name: Glucose 1-phosphate ↔ Glucose 6-phosphate
conversion direction: REVERSIBLE

Reference/KEGG Compound C00984
type: UnificationXref
id: C00984
db: KEGG Compound

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Pyrophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyrophosphate

Reference/BioCyc GLC-6-P
type: UnificationXref
id: GLC-6-P
db: BioCyc

Reference/KEGG Compound C00190
type: UnificationXref
id: C00190
db: KEGG Compound

ReactionCatalysis100464
type: Catalysis
controller: UDP-glucose 4-epimerase
controlled: Reaction110156
control type: ACTIVATION

ReactionCatalysis100463
type: Catalysis
controller: Unknown
controlled: 4.1.1.35
control type: ACTIVATION

ReactionCatalysis100462
type: Catalysis
controller: UDP-glucose 6-dehydrogenase
controlled: 1.1.1.22
control type: ACTIVATION

Reference/ChemSpider 17069
type: UnificationXref
id: 17069
db: ChemSpider

Reference/HMDB HMDB0001018
type: UnificationXref
id: HMDB0001018
db: HMDB

Reference/ChEBI CHEBI 16082
type: UnificationXref
id: CHEBI:16082
db: ChEBI

Reference/HMDB HMDB0000286
type: UnificationXref
id: HMDB0000286
db: HMDB

Reference/HMDB HMDB0000285
type: UnificationXref
id: HMDB0000285
db: HMDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Compound/PW C000746 Golgi apparatus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucuronic acid
stoichiometric coefficient: 1.0

Compound/PW C000721 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 2.0

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/PathWhiz PW000146
type: UnificationXref
id: PW000146
db: PathWhiz

Protein/7725 Cytoplasm/Stoichiometry/8.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 8.0

Reference/KEGG Compound C00075
type: UnificationXref
id: C00075
db: KEGG Compound

Golgi apparatus
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005794

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Compound/PW C001034 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/PubChem-compound 439357
type: UnificationXref
id: 439357
db: PubChem-compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

ChemicalStructure/PW C000093
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

UDP-glucose 4-epimerase
type: Complex
component stoichiometry: Protein/7725 Cytoplasm/Stoichiometry/2.0
cellular location: Cytoplasm
component: Unknown

Compound/PW C001851 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Compound/PW C000093 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Galactose
stoichiometric coefficient: 1.0

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PathWhiz PW121816
type: UnificationXref
id: PW121816
db: PathWhiz

Glucose 1-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001586
xref: Reference/PubChem-compound 439165
xref: Reference/CAS 59-56-3
xref: Reference/BioCyc GLC-1-P
xref: Reference/ChEBI CHEBI 16077
xref: Reference/KEGG Compound C00103
xref: Reference/ChemSpider 388311
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001207

Compound/PW C000746 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucuronic acid
stoichiometric coefficient: 1.0

Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00092
type: UnificationXref
id: C00092
db: KEGG Compound

Reference/ChemSpider 71358
type: UnificationXref
id: 71358
db: ChemSpider

1.1.1.22
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000721 Cytoplasm/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytoplasm/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000746 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000193 Cytoplasm/Stoichiometry/1.0
right: Uridine diphosphate glucuronic acid
right: NADH
spontaneous: false
EC number: 1.1.1.22
left: Water
left: NAD
left: Uridine diphosphate glucose
name: 2 NAD + Uridine diphosphate glucose + Water → 2 NADH + Uridine diphosphate glucuronic acid
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/CAS 2255-14-3
type: UnificationXref
id: 2255-14-3
db: CAS

Reference/PubChem-compound 79025
type: UnificationXref
id: 79025
db: PubChem-compound

4.1.1.35
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000746 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000805 Golgi apparatus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Golgi apparatus/Stoichiometry/1.0
right: Carbon dioxide
right: UDP-D-Xylose
spontaneous: false
EC number: 4.1.1.35
left: Uridine diphosphate glucuronic acid
name: Uridine diphosphate glucuronic acid → Carbon dioxide + UDP-D-Xylose
conversion direction: LEFT_TO_RIGHT

Reaction110156
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000504 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000206 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000193 Cytoplasm/Stoichiometry/1.0
right: Glucose 1-phosphate
right: Uridine diphosphategalactose
spontaneous: false
left: Galactose 1-phosphate
left: Uridine diphosphate glucose
name: Galactose 1-phosphate + Uridine diphosphate glucose ↔ Glucose 1-phosphate + Uridine diphosphategalactose
conversion direction: REVERSIBLE

ReactionCatalysis100400
type: Catalysis
controller: Galactose-1-phosphate uridylyltransferase
controlled: 2.7.7.12
control type: ACTIVATION

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Uridine diphosphategalactose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 67119
xref: Reference/ChemSpider 17069
xref: Reference/KEGG Compound C00052
xref: Reference/HMDB HMDB0000302
xref: Reference/PubChem-compound 18068
xref: Reference/CAS 2956-16-3
xref: Reference/BioCyc UDP-GLACTOSE
chemical formula: C15H24N2O17P2
molecular weight: 566.055
structure: ChemicalStructure/PW C000206

Reference/CAS 56-73-5
type: UnificationXref
id: 56-73-5
db: CAS

ChemicalStructure/PW C000746
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000504
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0003345
type: UnificationXref
id: HMDB0003345
db: HMDB

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Carbon dioxide
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Carbon dioxide

Galactose-1-phosphate uridylyltransferase
type: Complex
component stoichiometry: Protein/7725 Cytoplasm/Stoichiometry/2.0
cellular location: Cytoplasm
component: Unknown

UDP-D-Xylose
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: UDP-D-Xylose

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

ChemicalStructure/PW C000193
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000192
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/CAS 63-39-8
type: UnificationXref
id: 63-39-8
db: CAS

Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Glucose 6-phosphate

Uridine diphosphate glucuronic acid
type: SmallMolecule
cellular location: Golgi apparatus
entity reference: Uridine diphosphate glucuronic acid

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

ChemicalStructure/PW C001851
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000645
type: UnificationXref
id: HMDB0000645
db: HMDB

UDP-glucose 6-dehydrogenase
type: Complex
component stoichiometry: Protein/7725 Cytoplasm/Stoichiometry/6.0
cellular location: Cytoplasm
component: Unknown

NAD
type: SmallMolecule
cellular location: Cytoplasm
entity reference: NAD