Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/KEGG Compound C00798
type: UnificationXref
id: C00798
db: KEGG Compound

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Compound/PW C001316 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Transport10043
type: Transport
participant stoichiometry: Compound/PW C001049 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001049 Peroxisome/Stoichiometry/1.0
right: Phytanoyl-CoA
spontaneous: false
left: Phytanoyl-CoA
name: Phytanoyl-CoA (→) Transport: Rattus norvegicus, Cell, Cytoplasm to Rattus norvegicus, Cell, Peroxisome
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 49189
type: UnificationXref
id: CHEBI:49189
db: ChEBI

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Reference/KEGG Compound C02060
type: UnificationXref
id: C02060
db: KEGG Compound

Fatty aldehyde dehydrogenase
type: Protein
cellular location: Peroxisome
entity reference: Fatty aldehyde dehydrogenase

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

ChemicalStructure/PW C001309
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)CCCC(C)CCCC(C)CCCC(C)C=O

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Carbon dioxide
type: SmallMolecule
cellular location: Peroxisome
entity reference: Carbon dioxide

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Isobutyryl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 3036931
xref: Reference/ChemSpider 2300823
xref: Reference/BioCyc ISOBUTYRYL-COA
xref: Reference/ChEBI CHEBI 15479
xref: Reference/CAS 15621-60-0
xref: Reference/HMDB HMDB0001243
xref: Reference/KEGG Compound C00630
chemical formula: C25H42N7O17P3S
molecular weight: 837.15704
structure: ChemicalStructure/PW C000960

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

NAD
type: SmallMolecule
cellular location: Peroxisome
entity reference: NAD

Phytanoyl-CoA dioxygenase, peroxisomal
type: Protein
cellular location: Peroxisome
entity reference: Phytanoyl-CoA dioxygenase, peroxisomal

SubPathwayInteraction108537
type: Interaction
name: SubPathwayReaction
name: SubPathway108537Reaction
participant: Pristanic acid
participant: Acetyl-CoA
participant: Propionyl-CoA
participant: Isobutyryl-CoA

SubPathwayInteraction108538
type: Interaction
name: SubPathwayReaction
name: SubPathway108538Reaction
participant: Pristanic acid

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PathWhiz PW000041
type: UnificationXref
id: PW000041
db: PathWhiz

Compound/PW C001099 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

Reference/BioCyc ISOBUTYRYL-COA
type: UnificationXref
id: ISOBUTYRYL-COA
db: BioCyc

Reference/HMDB HMDB0000795
type: UnificationXref
id: HMDB0000795
db: HMDB

ChemicalStructure/PW C001883
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Very long-chain acyl-CoA synthetase
type: ProteinReference
xref: Reference/UniProt P97524
organism: Rattus norvegicus

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Phytanoyl-CoA dioxygenase, peroxisomal
type: ProteinReference
xref: Reference/UniProt Q9QY64
organism: Rattus norvegicus

Reference/KEGG Compound C00100
type: UnificationXref
id: C00100
db: KEGG Compound

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/CAS 1189-37-3
type: UnificationXref
id: 1189-37-3
db: CAS

Reference/PubChem-compound 439164
type: UnificationXref
id: 439164
db: PubChem-compound

Rattus norvegicus
type: BioSource
xref: Reference/TAXONOMY 10116

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/PathWhiz PW122010
type: UnificationXref
id: PW122010
db: PathWhiz

2-hydroxyacyl-CoA lyase 1
type: ProteinReference
xref: Reference/UniProt Q8CHM7
organism: Rattus norvegicus

Acetyl-CoA
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Acetyl-CoA
name: SubPathwayOutput

1.14.11.18
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000134 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000999 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001049 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Peroxisome/Stoichiometry/1.0
right: Succinic acid
right: Carbon dioxide
right: 2-Hydroxyphytanoyl-CoA
spontaneous: false
EC number: 1.14.11.18
left: Oxygen
left: Oxoglutaric acid
left: Phytanoyl-CoA
name: Oxoglutaric acid + Oxygen + Phytanoyl-CoA → 2-Hydroxyphytanoyl-CoA + Carbon dioxide + Succinic acid
conversion direction: LEFT_TO_RIGHT

1.2.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001144 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001309 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000635 Peroxisome/Stoichiometry/1.0
right: Pristanic acid
right: NADH
spontaneous: false
EC number: 1.2.1.3
left: Water
left: Pristanal
left: NAD
name: NAD + Pristanal + Water → NADH + Pristanic acid
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15522
type: UnificationXref
id: CHEBI:15522
db: ChEBI

Propionyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 317-66-8
xref: Reference/PubChem-compound 439164
xref: Reference/KEGG Compound C00100
xref: Reference/ChEBI CHEBI 15539
xref: Reference/BioCyc PROPIONYL-COA
xref: Reference/ChemSpider 388310
xref: Reference/HMDB HMDB0001275
chemical formula: C24H40N7O17P3S
molecular weight: 823.1414
structure: ChemicalStructure/PW C000988

Compound/PW C000999 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Hydroxyphytanoyl-CoA
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Peroxisome
entity reference: Water

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Formyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Formyl-CoA

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

Compound/PW C001049 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phytanoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 388310
type: UnificationXref
id: 388310
db: ChemSpider

Reference/BioCyc SUC
type: UnificationXref
id: SUC
db: BioCyc

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Reference/ChEBI CHEBI 51340
type: UnificationXref
id: CHEBI:51340
db: ChEBI

2-hydroxyacyl-CoA lyase 1
type: Protein
cellular location: Peroxisome
entity reference: 2-hydroxyacyl-CoA lyase 1

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

4.1.-.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000999 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001309 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001883 Peroxisome/Stoichiometry/1.0
right: Pristanal
right: Formyl-CoA
spontaneous: false
EC number: 4.1.-.-
left: 2-Hydroxyphytanoyl-CoA
name: 2-Hydroxyphytanoyl-CoA → Formyl-CoA + Pristanal
conversion direction: LEFT_TO_RIGHT

Reaction147268
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000639 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001049 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
right: Phytanoyl-CoA
right: Adenosine diphosphate
right: Pyrophosphate
spontaneous: false
left: Phytanic acid
left: Adenosine triphosphate
left: Coenzyme A
name: Adenosine triphosphate + Coenzyme A + Phytanic acid → Adenosine diphosphate + Phytanoyl-CoA + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

2-Hydroxyphytanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15475
xref: Reference/KEGG Compound C07343
xref: Reference/BioCyc 2-HYDROXYPHYTANOYL-COA
xref: Reference/PubChem-compound 441263
xref: Reference/ChemSpider 390032
xref: Reference/CAS 172787-73-4
xref: Reference/HMDB HMDB0001295
chemical formula: C41H74N7O18P3S
molecular weight: 1077.4023
structure: ChemicalStructure/PW C000999

Reference/ChemSpider 388444
type: UnificationXref
id: 388444
db: ChemSpider

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Pristanic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 51340
xref: Reference/HMDB HMDB0000795
xref: Reference/CAS 1189-37-3
xref: Reference/ChemSpider 110458
xref: Reference/PubChem-compound 123929
chemical formula: C19H38O2
molecular weight: 298.28717
structure: ChemicalStructure/PW C000635

Phytanoyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-206
xref: Reference/HMDB HMDB0001359
xref: Reference/CAS 146622-45-9
xref: Reference/KEGG Compound C02060
xref: Reference/PubChem-compound 439640
xref: Reference/ChemSpider 388712
xref: Reference/ChEBI CHEBI 15538
chemical formula: C41H74N7O17P3S
molecular weight: 1061.4075
structure: ChemicalStructure/PW C001049

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/BioCyc PROPIONYL-COA
type: UnificationXref
id: PROPIONYL-COA
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Phytanic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 26840
xref: Reference/CAS 14721-66-5
xref: Reference/KEGG Compound C01607
xref: Reference/ChemSpider 25001
xref: Reference/HMDB HMDB0000801
xref: Reference/ChEBI CHEBI 16285
chemical formula: C20H40O2
molecular weight: 312.30283
structure: ChemicalStructure/PW C000639

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Protein/15925 Peroxisome/Stoichiometry/4.0
type: Stoichiometry
physical entity: 2-hydroxyacyl-CoA lyase 1
stoichiometric coefficient: 4.0

Reference/CAS 13131-49-2
type: UnificationXref
id: 13131-49-2
db: CAS

Reference/UniProt Q8CHM7
type: UnificationXref
id: Q8CHM7
db: UniProt

Reference/ChemSpider 13628282
type: UnificationXref
id: 13628282
db: ChemSpider

Reference/ChEBI CHEBI 15741
type: UnificationXref
id: CHEBI:15741
db: ChEBI

Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Beta Oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108537
pathway component: SubPathwayInteraction108537
name: SubPathway

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine triphosphate

Reference/PubChem-compound 441263
type: UnificationXref
id: 441263
db: PubChem-compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/PubChem-compound 1110
type: UnificationXref
id: 1110
db: PubChem-compound

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Reference/PubChem-compound 26840
type: UnificationXref
id: 26840
db: PubChem-compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/UniProt P97524
type: UnificationXref
id: P97524
db: UniProt

Compound/PW C001049 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phytanoyl-CoA
stoichiometric coefficient: 1.0

Succinic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000254
xref: Reference/CAS 110-15-6
xref: Reference/ChEBI CHEBI 15741
xref: Reference/KEGG Compound C00042
xref: Reference/ChemSpider 1078
xref: Reference/PubChem-compound 1110
xref: Reference/BioCyc SUC
chemical formula: C4H6O4
molecular weight: 118.02661
structure: ChemicalStructure/PW C000174

Reference/BioCyc CPD-206
type: UnificationXref
id: CPD-206
db: BioCyc

Reference/PubChem-compound 3036931
type: UnificationXref
id: 3036931
db: PubChem-compound

Compound/PW C000174 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

Reference/BioCyc FORMYL-COA
type: UnificationXref
id: FORMYL-COA
db: BioCyc

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Compound/PW C000635 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanic acid
stoichiometric coefficient: 1.0

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/ChEBI CHEBI 16285
type: UnificationXref
id: CHEBI:16285
db: ChEBI

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/CAS 317-66-8
type: UnificationXref
id: 317-66-8
db: CAS

Reference/KEGG Compound C07343
type: UnificationXref
id: C07343
db: KEGG Compound

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Reference/PubChem-compound 439640
type: UnificationXref
id: 439640
db: PubChem-compound

Coenzyme A
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Coenzyme A

Refsum Disease
type: Pathway
pathway order: PathwayTransport/2114164
pathway order: PathwayEnzymeReaction/2114160
pathway order: PathwaySubPathway/108537
pathway order: PathwaySubPathway/108538
pathway order: PathwayEnzymeReaction/2114163
pathway order: PathwayEnzymeReaction/2114162
pathway order: PathwayEnzymeReaction/2114161
pathway component: 1.14.11.18
pathway component: ReactionCatalysis137500
pathway component: 1.2.1.3
pathway component: Transport10043
pathway component: Phytanic Acid Peroxisomal Oxidation
pathway component: ReactionCatalysis137502
pathway component: Beta Oxidation
pathway component: 4.1.-.-
pathway component: TransportCatalysis1255
pathway component: Reaction147268
pathway component: ReactionCatalysis137503
pathway component: ReactionCatalysis137504
xref: Reference/PathWhiz PW122010
xref: Reference/SMPDB SMP0120749
organism: Rattus norvegicus

Phytanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Phytanoyl-CoA

Reference/ChemSpider 2300823
type: UnificationXref
id: 2300823
db: ChemSpider

Pristanic acid
type: SmallMolecule
cellular location: Peroxisome
entity reference: Pristanic acid
name: SubPathwayInput

Reference/HMDB HMDB0000801
type: UnificationXref
id: HMDB0000801
db: HMDB

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/TAXONOMY 10116
type: UnificationXref
id: 10116
db: TAXONOMY

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Reference/HMDB HMDB0000254
type: UnificationXref
id: HMDB0000254
db: HMDB

Peroxisome
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005777

ChemicalStructure/PW C000174
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(O)=O

Reference/PubChem-compound 439313
type: UnificationXref
id: 439313
db: PubChem-compound

Reference/CAS 105373-75-9
type: UnificationXref
id: 105373-75-9
db: CAS

Formyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 13131-49-2
xref: Reference/ChEBI CHEBI 15522
xref: Reference/ChemSpider 388444
xref: Reference/KEGG Compound C00798
xref: Reference/PubChem-compound 439313
xref: Reference/BioCyc FORMYL-COA
xref: Reference/HMDB HMDB0003419
chemical formula: C22H36N7O17P3S
molecular weight: 795.1101
structure: ChemicalStructure/PW C001883

Reference/ChemSpider 390032
type: UnificationXref
id: 390032
db: ChemSpider

Reference/CAS 172787-73-4
type: UnificationXref
id: 172787-73-4
db: CAS

2-Hydroxyphytanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: 2-Hydroxyphytanoyl-CoA

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Isobutyryl-CoA
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Isobutyryl-CoA
name: SubPathwayOutput

ReactionCatalysis137500
type: Catalysis
controller: Very long-chain acyl-CoA synthetase
controlled: Reaction147268
control type: ACTIVATION

ReactionCatalysis137502
type: Catalysis
controller: 2-hydroxyacyl-CoA lyase 1
controlled: 4.1.-.-
control type: ACTIVATION

Phytanic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Phytanic acid

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

ATP-binding cassette sub-family D member 2
type: Protein
entity reference: ATP-binding cassette sub-family D member 2

NADH
type: SmallMolecule
cellular location: Peroxisome
entity reference: NADH

2-hydroxyacyl-CoA lyase 1
type: Complex
component stoichiometry: Protein/15925 Peroxisome/Stoichiometry/4.0
cellular location: Peroxisome
component: 2-hydroxyacyl-CoA lyase 1

Reference/KEGG Compound C00042
type: UnificationXref
id: C00042
db: KEGG Compound

Compound/PW C000639 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phytanic acid
stoichiometric coefficient: 1.0

Reference/UniProt P30839
type: UnificationXref
id: P30839
db: UniProt

ReactionCatalysis137503
type: Catalysis
controller: Fatty aldehyde dehydrogenase
controlled: 1.2.1.3
control type: ACTIVATION

Reference/ChemSpider 1078
type: UnificationXref
id: 1078
db: ChemSpider

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

ReactionCatalysis137504
type: Catalysis
controller: Phytanoyl-CoA dioxygenase, peroxisomal
controlled: 1.14.11.18
control type: ACTIVATION

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Oxygen
type: SmallMolecule
cellular location: Peroxisome
entity reference: Oxygen

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/BioCyc 2-HYDROXYPHYTANOYL-COA
type: UnificationXref
id: 2-HYDROXYPHYTANOYL-COA
db: BioCyc

Reference/HMDB HMDB0001359
type: UnificationXref
id: HMDB0001359
db: HMDB

Reference/ChemSpider 110458
type: UnificationXref
id: 110458
db: ChemSpider

Compound/PW C000721 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Compound/PW C001883 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Formyl-CoA
stoichiometric coefficient: 1.0

Reference/PubChem-compound 123929
type: UnificationXref
id: 123929
db: PubChem-compound

Compound/PW C001144 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000134 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 25001
type: UnificationXref
id: 25001
db: ChemSpider

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/HMDB HMDB0003419
type: UnificationXref
id: HMDB0003419
db: HMDB

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Phytanic Acid Peroxisomal Oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108538
pathway component: SubPathwayInteraction108538
xref: Reference/SMPDB SMP0000450
xref: Reference/PathWhiz PW000041
name: SubPathway

Pristanal
type: SmallMolecule
cellular location: Peroxisome
entity reference: Pristanal

Reference/ChEBI CHEBI 15539
type: UnificationXref
id: CHEBI:15539
db: ChEBI

Reference/ChEBI CHEBI 15538
type: UnificationXref
id: CHEBI:15538
db: ChEBI

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine diphosphate

Reference/CAS 15621-60-0
type: UnificationXref
id: 15621-60-0
db: CAS

Reference/HMDB HMDB0001243
type: UnificationXref
id: HMDB0001243
db: HMDB

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Pyrophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyrophosphate

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/UniProt Q9QY64
type: UnificationXref
id: Q9QY64
db: UniProt

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

ChemicalStructure/PW C000960
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005777
type: UnificationXref
id: GO:0005777
db: GENE ONTOLOGY

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Fatty aldehyde dehydrogenase
type: ProteinReference
xref: Reference/UniProt P30839
organism: Rattus norvegicus

Reference/CAS 14721-66-5
type: UnificationXref
id: 14721-66-5
db: CAS

Succinic acid
type: SmallMolecule
cellular location: Peroxisome
entity reference: Succinic acid

Reference/KEGG Compound C01607
type: UnificationXref
id: C01607
db: KEGG Compound

Oxoglutaric acid
type: SmallMolecule
cellular location: Peroxisome
entity reference: Oxoglutaric acid

Reference/ChemSpider 388712
type: UnificationXref
id: 388712
db: ChemSpider

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Compound/PW C001309 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pristanal
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Compound/PW C001034 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00630
type: UnificationXref
id: C00630
db: KEGG Compound

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Reference/CAS 110-15-6
type: UnificationXref
id: 110-15-6
db: CAS

Reference/PubChem-compound 14671060
type: UnificationXref
id: 14671060
db: PubChem-compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

ATP-binding cassette sub-family D member 2
type: ProteinReference
xref: Reference/UniProt Q9QY44

Reference/SMPDB SMP0120749
type: UnificationXref
id: SMP0120749
db: SMPDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

TransportCatalysis1255
type: Catalysis
controller: ATP-binding cassette sub-family D member 2
controlled: Transport10043
control type: ACTIVATION

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Phytanoyl-CoA
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Phytanoyl-CoA

Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/UniProt Q9QY44
type: UnificationXref
id: Q9QY44
db: UniProt

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/SMPDB SMP0000450
type: UnificationXref
id: SMP0000450
db: SMPDB

Reference/HMDB HMDB0001275
type: UnificationXref
id: HMDB0001275
db: HMDB

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/HMDB HMDB0001958
type: UnificationXref
id: HMDB0001958
db: HMDB

ChemicalStructure/PW C000988
type: ChemicalStructure
structure format: SMILES

Compound/PW C001420 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Reference/CAS 146622-45-9
type: UnificationXref
id: 146622-45-9
db: CAS

ChemicalStructure/PW C001049
type: ChemicalStructure
structure format: SMILES

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Very long-chain acyl-CoA synthetase
type: Protein
cellular location: Cytoplasm
entity reference: Very long-chain acyl-CoA synthetase

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/ChEBI CHEBI 15475
type: UnificationXref
id: CHEBI:15475
db: ChEBI

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

Reference/ChEBI CHEBI 15479
type: UnificationXref
id: CHEBI:15479
db: ChEBI

ChemicalStructure/PW C000635
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)CCCC(C)CCCC(C)CCCC(C)C(O)=O

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

ChemicalStructure/PW C000639
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O)=O

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Propionyl-CoA
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Propionyl-CoA
name: SubPathwayOutput

ChemicalStructure/PW C000999
type: ChemicalStructure
structure format: SMILES

Pristanal
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 49189
xref: Reference/ChemSpider 13628282
xref: Reference/CAS 105373-75-9
xref: Reference/PubChem-compound 14671060
xref: Reference/HMDB HMDB0001958
chemical formula: C19H38O
molecular weight: 282.29227
structure: ChemicalStructure/PW C001309

Compound/PW C001065 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 1.0

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/HMDB HMDB0001295
type: UnificationXref
id: HMDB0001295
db: HMDB