Reference/ChemSpider 10724
type: UnificationXref
id: 10724
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/PubChem-compound 3082227
type: UnificationXref
id: 3082227
db: PubChem-compound

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/PubChem-compound 65113
type: UnificationXref
id: 65113
db: PubChem-compound

Reference/KEGG Compound C00318
type: UnificationXref
id: C00318
db: KEGG Compound

6.2.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002751 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001589 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hexacosanoyl-CoA
spontaneous: false
EC number: 6.2.1.3
left: Adenosine triphosphate
left: Hexacosanoic acid
left: Coenzyme A
name: Adenosine triphosphate + Coenzyme A + Hexacosanoic acid → Adenosine diphosphate + Hexacosanoyl-CoA
conversion direction: LEFT_TO_RIGHT

Transport10046
type: Transport
participant stoichiometry: Compound/PW C002751 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002751 Peroxisome/Stoichiometry/1.0
right: Hexacosanoyl-CoA
spontaneous: false
left: Hexacosanoyl-CoA
name: Hexacosanoyl-CoA (→) Transport: Rattus norvegicus, Cell, Cytosol to Rattus norvegicus, Cell, Peroxisome
conversion direction: LEFT_TO_RIGHT

Dodecanoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Dodecanoic acid

ChemicalStructure/PW C002751
type: ChemicalStructure
structure format: SMILES

Transport10045
type: Transport
participant stoichiometry: Compound/PW C002794 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002794 Cytosol/Stoichiometry/1.0
right: Tetracosanoyl-CoA
spontaneous: false
left: Tetracosanoyl-CoA
name: Tetracosanoyl-CoA (→) Transport: Rattus norvegicus, Cell, Cytosol to Rattus norvegicus, Cell, Peroxisome
conversion direction: LEFT_TO_RIGHT

Long-chain-fatty-acid--CoA ligase ACSBG2
type: Protein
cellular location: Cytosol
entity reference: Long-chain-fatty-acid--CoA ligase ACSBG2

2.3.1.7
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000129 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Mitochondrion/Stoichiometry/1.0
right: Coenzyme A
right: Acetyl-CoA
spontaneous: false
EC number: 2.3.1.7
left: L-Acetylcarnitine
left: L-Carnitine
name: L-Acetylcarnitine + L-Carnitine → Acetyl-CoA + Coenzyme A
conversion direction: LEFT_TO_RIGHT

2.3.1.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000497 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001928 Cytosol/Stoichiometry/1.0
right: Lauroyl-CoA
right: L-Carnitine
spontaneous: false
EC number: 2.3.1.21
left: Coenzyme A
left: Dodecanoic acid
name: Coenzyme A + Dodecanoic acid → L-Carnitine + Lauroyl-CoA
conversion direction: LEFT_TO_RIGHT

2.3.1.137
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001928 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000497 Peroxisome/Stoichiometry/1.0
right: Coenzyme A
right: Dodecanoic acid
spontaneous: false
EC number: 2.3.1.137
left: Lauroyl-CoA
name: Lauroyl-CoA → Coenzyme A + Dodecanoic acid
conversion direction: LEFT_TO_RIGHT

Lauroyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc LAUROYLCOA-CPD
xref: Reference/KEGG Compound C01832
xref: Reference/ChEBI CHEBI 15521
xref: Reference/HMDB HMDB0003571
xref: Reference/CAS 6244-92-4
xref: Reference/ChemSpider 145018
xref: Reference/PubChem-compound 165436
chemical formula: C33H56N7O17P3S
molecular weight: 947.2666
structure: ChemicalStructure/PW C001928

2.3.1.7
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000129 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Peroxisome/Stoichiometry/1.0
right: Coenzyme A
right: L-Acetylcarnitine
spontaneous: false
EC number: 2.3.1.7
left: L-Carnitine
left: Acetyl-CoA
name: Acetyl-CoA + L-Carnitine → Coenzyme A + L-Acetylcarnitine
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Acetyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Acetyl-CoA

Protein/7758/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

L-Acetylcarnitine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Acetylcarnitine

Beta oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108685
pathway component: SubPathwayInteraction108685
name: SubPathway

Beta oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108683
pathway component: SubPathwayInteraction108683
name: SubPathway

Beta oxidation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108684
pathway component: SubPathwayInteraction108684
name: SubPathway

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/HMDB HMDB0006526
type: UnificationXref
id: HMDB0006526
db: HMDB

Lauroyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Lauroyl-CoA

Tetracosanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Tetracosanoyl-CoA
name: SubPathwayInput

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

L-Carnitine
type: SmallMoleculeReference
xref: Reference/BioCyc CARNITINE
xref: Reference/ChEBI CHEBI 16347
xref: Reference/PubChem-compound 10917
xref: Reference/CAS 541-15-1
xref: Reference/KEGG Compound C00318
xref: Reference/HMDB HMDB0000062
xref: Reference/ChemSpider 10455
chemical formula: C7H15NO3
molecular weight: 161.1052
structure: ChemicalStructure/PW C000044

6.2.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001340 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002794 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Tetracosanoyl-CoA
spontaneous: false
EC number: 6.2.1.3
left: Adenosine triphosphate
left: Tetracosanoic acid
left: Coenzyme A
name: Adenosine triphosphate + Coenzyme A + Tetracosanoic acid → Adenosine diphosphate + Tetracosanoyl-CoA
conversion direction: LEFT_TO_RIGHT

L-Acetylcarnitine
type: SmallMoleculeReference
xref: Reference/CAS 3040-38-8
xref: Reference/PubChem-compound 1
xref: Reference/ChemSpider 21243783
xref: Reference/HMDB HMDB0000201
xref: Reference/KEGG Compound C02571
xref: Reference/BioCyc (-)o-acetylcarnitine
xref: Reference/ChEBI CHEBI 73024
chemical formula: C9H17NO4
molecular weight: 203.11575
structure: ChemicalStructure/PW C000129

Lauroyl-CoA
type: SmallMolecule
entity reference: Lauroyl-CoA
name: SubPathwayOutput

Dodecanoic acid
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Dodecanoic acid

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 25202335
type: UnificationXref
id: 25202335
db: PubChem-compound

Acetyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Acetyl-CoA

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Tetracosanoic acid
type: SmallMoleculeReference
xref: Reference/ChemSpider 10724
xref: Reference/HMDB HMDB0002003
xref: Reference/PubChem-compound 11197
xref: Reference/KEGG Compound C08320
xref: Reference/ChEBI CHEBI 28866
xref: Reference/BioCyc TETRACOSANOATE
xref: Reference/CAS 557-59-5
chemical formula: C24H48O2
molecular weight: 368.36542
structure: ChemicalStructure/PW C001340

Reference/HMDB HMDB0001521
type: UnificationXref
id: HMDB0001521
db: HMDB

Lauroyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Lauroyl-CoA
name: SubPathwayInput

Tetracosanoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 24305-30-4
xref: Reference/ChEBI CHEBI 52974
xref: Reference/PubChem-compound 3082227
xref: Reference/HMDB HMDB0006526
xref: Reference/KEGG Compound C16529
chemical formula: C45H82N7O17P3S
molecular weight: 1117.4701
structure: ChemicalStructure/PW C002794

Dodecanoic acid
type: SmallMoleculeReference
xref: Reference/ChemSpider 3756
xref: Reference/KEGG Compound C02679
xref: Reference/CAS 143-07-7
xref: Reference/ChEBI CHEBI 30805
xref: Reference/HMDB HMDB0000638
xref: Reference/PubChem-compound 3893
chemical formula: C12H24O2
molecular weight: 200.17763
structure: ChemicalStructure/PW C000497

L-Carnitine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Carnitine

Compound/PW C000129 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

ReactionCatalysis101150
type: Catalysis
controller: Long-chain-fatty-acid--CoA ligase ACSBG2
controlled: 6.2.1.3
control type: ACTIVATION

Hexacosanoic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0002356
xref: Reference/ChEBI CHEBI 31009
xref: Reference/CAS 506-46-7
xref: Reference/PubChem-compound 10469
xref: Reference/BioCyc 2-PG
xref: Reference/ChemSpider 10037
chemical formula: C26H52O2
molecular weight: 396.39673
structure: ChemicalStructure/PW C001589

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA
name: SubPathwayOutput

Compound/PW C000044 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Carnitine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/CAS 3040-38-8
type: UnificationXref
id: 3040-38-8
db: CAS

Reference/HMDB HMDB0000201
type: UnificationXref
id: HMDB0000201
db: HMDB

ReactionCatalysis101155
type: Catalysis
controller: Carnitine O-palmitoyltransferase 1, brain isoform
controlled: 2.3.1.21
control type: ACTIVATION

ReactionCatalysis101154
type: Catalysis
controller: Carnitine O-palmitoyltransferase 1, brain isoform
controlled: 2.3.1.7
control type: ACTIVATION

ReactionCatalysis101153
type: Catalysis
controller: Carnitine O-palmitoyltransferase 1, brain isoform
controlled: 2.3.1.7
control type: ACTIVATION

Rattus norvegicus
type: BioSource
xref: Reference/TAXONOMY 10116

ReactionCatalysis101152
type: Catalysis
controller: Carnitine O-palmitoyltransferase 1, brain isoform
controlled: 2.3.1.137
control type: ACTIVATION

L-Acetylcarnitine
type: SmallMolecule
cellular location: Mitochondrion
entity reference: L-Acetylcarnitine

ReactionCatalysis101151
type: Catalysis
controller: Long-chain-fatty-acid--CoA ligase ACSBG2
controlled: 6.2.1.3
control type: ACTIVATION

Mitochondrion
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005739

Compound/PW C002794 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Tetracosanoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 28184701
type: UnificationXref
id: 28184701
db: ChemSpider

Reference/ChemSpider 10037
type: UnificationXref
id: 10037
db: ChemSpider

Reference/ChEBI CHEBI 15521
type: UnificationXref
id: CHEBI:15521
db: ChEBI

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/CAS 541-15-1
type: UnificationXref
id: 541-15-1
db: CAS

ChemicalStructure/PW C000129
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Compound/PW C001099 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/UniProt Q642G4
type: UnificationXref
id: Q642G4
db: UniProt

Reference/CAS 506-46-7
type: UnificationXref
id: 506-46-7
db: CAS

Protein/14622/Stoichiometry/1.0
type: Stoichiometry
physical entity: Peroxisomal membrane protein PEX14
stoichiometric coefficient: 1.0

Reference/BioCyc LAUROYLCOA-CPD
type: UnificationXref
id: LAUROYLCOA-CPD
db: BioCyc

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001340
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCCCCCCCCCC(O)=O

ChemicalStructure/PW C000497
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCC(O)=O

ChemicalStructure/PW C002794
type: ChemicalStructure
structure format: SMILES

Reference/PathWhiz PW122062
type: UnificationXref
id: PW122062
db: PathWhiz

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Compound/PW C000129 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15532
type: UnificationXref
id: CHEBI:15532
db: ChEBI

ChemicalStructure/PW C001589
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O

Lauroyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Lauroyl-CoA

Compound/PW C002794 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Tetracosanoyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc TETRADECANOYL-COA
type: UnificationXref
id: TETRADECANOYL-COA
db: BioCyc

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Compound/PW C001928 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lauroyl-CoA
stoichiometric coefficient: 1.0

Reference/GENE ONTOLOGY GO 0005759
type: UnificationXref
id: GO:0005759
db: GENE ONTOLOGY

Tetradecanoyl-CoA
type: SmallMolecule
entity reference: Tetradecanoyl-CoA
name: SubPathwayOutput

Tetradecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 3130-72-1
xref: Reference/HMDB HMDB0001521
xref: Reference/KEGG Compound C02593
xref: Reference/ChEBI CHEBI 15532
xref: Reference/ChemSpider 58623
xref: Reference/PubChem-compound 65113
xref: Reference/BioCyc TETRADECANOYL-COA
chemical formula: C35H62N7O17P3S
molecular weight: 977.3136
structure: ChemicalStructure/PW C001171

Reference/CAS 3130-72-1
type: UnificationXref
id: 3130-72-1
db: CAS

Coenzyme A
type: SmallMolecule
cellular location: Cytosol
entity reference: Coenzyme A

Reference/KEGG Compound C02679
type: UnificationXref
id: C02679
db: KEGG Compound

Compound/PW C000940 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/ChEBI CHEBI 73024
type: UnificationXref
id: CHEBI:73024
db: ChEBI

Compound/PW C001589 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hexacosanoic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 3893
type: UnificationXref
id: 3893
db: PubChem-compound

Reference/PubChem-compound 1
type: UnificationXref
id: 1
db: PubChem-compound

Reference/HMDB HMDB0006459
type: UnificationXref
id: HMDB0006459
db: HMDB

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

L-Carnitine
type: SmallMolecule
cellular location: Mitochondrion
entity reference: L-Carnitine

Compound/PW C001928 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lauroyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc CARNITINE
type: UnificationXref
id: CARNITINE
db: BioCyc

Mitochondrial 2-oxodicarboxylate carrier
type: Protein
entity reference: Mitochondrial 2-oxodicarboxylate carrier

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Peroxisomal membrane protein PEX14
type: Protein
entity reference: Peroxisomal membrane protein PEX14

Reference/UniProt F1LN46
type: UnificationXref
id: F1LN46
db: UniProt

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Reference/KEGG Compound C02571
type: UnificationXref
id: C02571
db: KEGG Compound

Reference/GENE ONTOLOGY GO 0005739
type: UnificationXref
id: GO:0005739
db: GENE ONTOLOGY

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/UniProt Q99JD3
type: UnificationXref
id: Q99JD3
db: UniProt

Compound/PW C000497 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dodecanoic acid
stoichiometric coefficient: 1.0

Transport1178
type: Transport
participant stoichiometry: Compound/PW C000497 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000497 Mitochondrion/Stoichiometry/1.0
right: Dodecanoic acid
spontaneous: false
left: Dodecanoic acid
name: Dodecanoic acid (→) Transport: Rattus norvegicus, Cell, Cytosol to Rattus norvegicus, Cell, Mitochondrion
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 58623
type: UnificationXref
id: 58623
db: ChemSpider

Transport1175
type: Transport
participant stoichiometry: Compound/PW C000497 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000497 Peroxisome/Stoichiometry/1.0
right: Dodecanoic acid
spontaneous: false
left: Dodecanoic acid
name: Dodecanoic acid (→) Transport: Rattus norvegicus, Cell, Peroxisome to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport1177
type: Transport
participant stoichiometry: Compound/PW C000129 Mitochondrial Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000129 Cytosol/Stoichiometry/1.0
right: L-Acetylcarnitine
spontaneous: false
left: L-Acetylcarnitine
name: L-Acetylcarnitine (→) Transport: Rattus norvegicus, Cell, Cytosol to Rattus norvegicus, Cell, Mitochondrial Matrix
conversion direction: LEFT_TO_RIGHT

Transport1176
type: Transport
participant stoichiometry: Compound/PW C000129 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000129 Cytosol/Stoichiometry/1.0
right: L-Acetylcarnitine
spontaneous: false
left: L-Acetylcarnitine
name: L-Acetylcarnitine (→) Transport: Rattus norvegicus, Cell, Peroxisome to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/TAXONOMY 10116
type: UnificationXref
id: 10116
db: TAXONOMY

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Peroxisome
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005777

Reference/KEGG Compound C08320
type: UnificationXref
id: C08320
db: KEGG Compound

Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 31009
type: UnificationXref
id: CHEBI:31009
db: ChEBI

Carnitine O-palmitoyltransferase 1, brain isoform
type: Protein
cellular location: Cytosol
entity reference: Carnitine O-palmitoyltransferase 1, brain isoform

Reference/BioCyc TETRACOSANOATE
type: UnificationXref
id: TETRACOSANOATE
db: BioCyc

L-Acetylcarnitine
type: SmallMolecule
cellular location: Peroxisome
entity reference: L-Acetylcarnitine

Mitochondrial Matrix
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005759

Compound/PW C002751 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hexacosanoyl-CoA
stoichiometric coefficient: 1.0

TransportCatalysis993
type: Catalysis
controller: Mitochondrial 2-oxodicarboxylate carrier
controlled: Transport1178
control type: ACTIVATION

TransportCatalysis992
type: Catalysis
controller: Mitochondrial 2-oxodicarboxylate carrier
controlled: Transport1177
control type: ACTIVATION

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

TransportCatalysis991
type: Catalysis
controller: Peroxisomal membrane protein
controlled: Transport1176
control type: ACTIVATION

Compound/PW C000129 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

ATP-binding cassette sub-family D member 2
type: Protein
entity reference: ATP-binding cassette sub-family D member 2

Peroxisomal membrane protein
type: Complex
component stoichiometry: Protein/7758/Stoichiometry/1.0
component stoichiometry: Protein/14622/Stoichiometry/1.0
component: Unknown
component: Peroxisomal membrane protein PEX14

Compound/PW C000044 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Carnitine
stoichiometric coefficient: 1.0

Unknown
type: Protein
entity reference: Unknown

L-Acetylcarnitine
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: L-Acetylcarnitine

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/PubChem-compound 10917
type: UnificationXref
id: 10917
db: PubChem-compound

Reference/KEGG Compound C02593
type: UnificationXref
id: C02593
db: KEGG Compound

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Reference/ChemSpider 10455
type: UnificationXref
id: 10455
db: ChemSpider

L-Carnitine
type: SmallMolecule
cellular location: Peroxisome
entity reference: L-Carnitine

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Coenzyme A
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Coenzyme A

Reference/UniProt A1L1K7
type: UnificationXref
id: A1L1K7
db: UniProt

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Tetracosanoyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Tetracosanoyl-CoA

Reference/PubChem-compound 10469
type: UnificationXref
id: 10469
db: PubChem-compound

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0120801
type: UnificationXref
id: SMP0120801
db: SMPDB

Reference/ChEBI CHEBI 28866
type: UnificationXref
id: CHEBI:28866
db: ChEBI

Reference/ChEBI CHEBI 64868
type: UnificationXref
id: CHEBI:64868
db: ChEBI

TransportCatalysis990
type: Catalysis
controller: Unknown
controlled: Transport1175
control type: ACTIVATION

ChemicalStructure/PW C001928
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C01832
type: UnificationXref
id: C01832
db: KEGG Compound

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C000044 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Carnitine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 165436
type: UnificationXref
id: 165436
db: PubChem-compound

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

ChemicalStructure/PW C000044
type: ChemicalStructure
structure format: SMILES
structure data: C[N+](C)(C)C[C@H](O)CC([O-])=O

Tetracosanoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Tetracosanoic acid

Compound/PW C000129 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

Reference/GENE ONTOLOGY GO 0005777
type: UnificationXref
id: GO:0005777
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 30805
type: UnificationXref
id: CHEBI:30805
db: ChEBI

Reference/KEGG Compound C16529
type: UnificationXref
id: C16529
db: KEGG Compound

Compound/PW C000497 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dodecanoic acid
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
cellular location: Peroxisome
entity reference: Coenzyme A

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/CAS 143-07-7
type: UnificationXref
id: 143-07-7
db: CAS

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Reference/BioCyc (-)o-acetylcarnitine
type: UnificationXref
id: (-)o-acetylcarnitine
db: BioCyc

Reference/ChemSpider 145018
type: UnificationXref
id: 145018
db: ChemSpider

Compound/PW C002751 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hexacosanoyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0002356
type: UnificationXref
id: HMDB0002356
db: HMDB

SubPathwayInteraction108685
type: Interaction
name: SubPathway108685Reaction
name: SubPathwayReaction
participant: Lauroyl-CoA
participant: Acetyl-CoA

ATP-binding cassette sub-family D member 2
type: ProteinReference
xref: Reference/UniProt Q9QY44

SubPathwayInteraction108683
type: Interaction
name: SubPathway108683Reaction
name: SubPathwayReaction
participant: Tetracosanoyl-CoA
participant: Acetyl-CoA
participant: Tetradecanoyl-CoA

SubPathwayInteraction108684
type: Interaction
name: SubPathwayReaction
name: SubPathway108684Reaction
participant: Hexacosanoyl-CoA
participant: Lauroyl-CoA
participant: Acetyl-CoA

TransportCatalysis1258
type: Catalysis
controller: ATP-binding cassette sub-family D member 2
controlled: Transport10046
control type: ACTIVATION

TransportCatalysis1257
type: Catalysis
controller: ATP-binding cassette sub-family D member 2
controlled: Transport10045
control type: ACTIVATION

Reference/ChEBI CHEBI 16347
type: UnificationXref
id: CHEBI:16347
db: ChEBI

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0002003
type: UnificationXref
id: HMDB0002003
db: HMDB

Reference/UniProt Q9QY44
type: UnificationXref
id: Q9QY44
db: UniProt

Carnitine-Acylcarnitine Translocase Deficiency
type: Pathway
pathway order: PathwaySubPathway/108683
pathway order: PathwaySubPathway/108684
pathway order: PathwaySubPathway/108685
pathway order: PathwayTransport/2115200
pathway order: PathwayTransport/2115199
pathway order: PathwayTransport/2115202
pathway order: PathwayTransport/2115201
pathway order: PathwayTransport/2115198
pathway order: PathwayTransport/2115197
pathway order: PathwayEnzymeReaction/2115194
pathway order: PathwayEnzymeReaction/2115193
pathway order: PathwayEnzymeReaction/2115192
pathway order: PathwayEnzymeReaction/2115191
pathway order: PathwayEnzymeReaction/2115196
pathway order: PathwayEnzymeReaction/2115195
pathway component: Transport1178
pathway component: Transport1175
pathway component: Transport1177
pathway component: Transport1176
pathway component: 6.2.1.3
pathway component: Transport10046
pathway component: Transport10045
pathway component: TransportCatalysis993
pathway component: TransportCatalysis992
pathway component: TransportCatalysis991
pathway component: 2.3.1.7
pathway component: TransportCatalysis1258
pathway component: TransportCatalysis990
pathway component: 2.3.1.21
pathway component: TransportCatalysis1257
pathway component: 2.3.1.137
pathway component: ReactionCatalysis101150
pathway component: Beta oxidation
pathway component: ReactionCatalysis101155
pathway component: ReactionCatalysis101154
pathway component: ReactionCatalysis101153
pathway component: ReactionCatalysis101152
pathway component: ReactionCatalysis101151
xref: Reference/SMPDB SMP0120801
xref: Reference/PathWhiz PW122062
organism: Rattus norvegicus

Long-chain-fatty-acid--CoA ligase ACSBG2
type: ProteinReference
xref: Reference/UniProt A1L1K7
organism: Rattus norvegicus

Reference/HMDB HMDB0003571
type: UnificationXref
id: HMDB0003571
db: HMDB

Reference/HMDB HMDB0000062
type: UnificationXref
id: HMDB0000062
db: HMDB

Mitochondrial 2-oxodicarboxylate carrier
type: ProteinReference
xref: Reference/UniProt Q99JD3

Peroxisomal membrane protein PEX14
type: ProteinReference
xref: Reference/UniProt Q642G4

Reference/PubChem-compound 11197
type: UnificationXref
id: 11197
db: PubChem-compound

Carnitine O-palmitoyltransferase 1, brain isoform
type: ProteinReference
xref: Reference/UniProt F1LN46
organism: Rattus norvegicus

Carnitine O-palmitoyltransferase 1, brain isoform
type: Protein
cellular location: Mitochondrion
entity reference: Carnitine O-palmitoyltransferase 1, brain isoform

Hexacosanoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Hexacosanoic acid

Dodecanoic acid
type: SmallMolecule
cellular location: Peroxisome
entity reference: Dodecanoic acid

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Unknown
type: ProteinReference

Reference/CAS 6244-92-4
type: UnificationXref
id: 6244-92-4
db: CAS

Reference/BioCyc 2-PG
type: UnificationXref
id: 2-PG
db: BioCyc

Reference/CAS 24305-30-4
type: UnificationXref
id: 24305-30-4
db: CAS

Reference/ChemSpider 21243783
type: UnificationXref
id: 21243783
db: ChemSpider

Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C001099 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Hexacosanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0006459
xref: Reference/ChEBI CHEBI 64868
xref: Reference/PubChem-compound 25202335
xref: Reference/ChemSpider 28184701
chemical formula: C47H82N7O17P3S
molecular weight: 1141.4701
structure: ChemicalStructure/PW C002751

Hexacosanoyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Hexacosanoyl-CoA

Reference/ChemSpider 3756
type: UnificationXref
id: 3756
db: ChemSpider

Reference/CAS 557-59-5
type: UnificationXref
id: 557-59-5
db: CAS

Reference/HMDB HMDB0000638
type: UnificationXref
id: HMDB0000638
db: HMDB

Carnitine O-palmitoyltransferase 1, brain isoform
type: Protein
cellular location: Peroxisome
entity reference: Carnitine O-palmitoyltransferase 1, brain isoform

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Compound/PW C001340 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Tetracosanoic acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 52974
type: UnificationXref
id: CHEBI:52974
db: ChEBI

Hexacosanoyl-CoA
type: SmallMolecule
cellular location: Peroxisome
entity reference: Hexacosanoyl-CoA
name: SubPathwayInput

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Compound/PW C000497 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dodecanoic acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001171
type: ChemicalStructure
structure format: SMILES