3-hydroxyacyl-CoA dehydrogenase type-2
type: Complex
component stoichiometry: Protein/15541 Mitochondrion/Stoichiometry/4.0
cellular location: Mitochondrion
component: 3-hydroxyacyl-CoA dehydrogenase type-2

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/ChemSpider 17220838
type: UnificationXref
id: 17220838
db: ChemSpider

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Compound/PW C002007 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxohexanoyl-CoA
stoichiometric coefficient: 1.0

3-Oxooctanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Oxooctanoyl-CoA

Compound/PW C002012 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Decenoyl-CoA
stoichiometric coefficient: 1.0

Lauroyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc LAUROYLCOA-CPD
xref: Reference/KEGG Compound C01832
xref: Reference/ChEBI CHEBI 15521
xref: Reference/HMDB HMDB0003571
xref: Reference/CAS 6244-92-4
xref: Reference/ChemSpider 145018
xref: Reference/PubChem-compound 165436
chemical formula: C33H56N7O17P3S
molecular weight: 947.2666
structure: ChemicalStructure/PW C001928

Reference/CAS 38795-33-4
type: UnificationXref
id: 38795-33-4
db: CAS

Reference/HMDB HMDB0001070
type: UnificationXref
id: HMDB0001070
db: HMDB

Reference/HMDB HMDB0006404
type: UnificationXref
id: HMDB0006404
db: HMDB

Reference/HMDB HMDB0006402
type: UnificationXref
id: HMDB0006402
db: HMDB

Compound/PW C001928 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lauroyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C000856 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Butyryl-CoA
stoichiometric coefficient: 1.0

Compound/PW C000145 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmitic acid
stoichiometric coefficient: 1.0

Protein/15546 Mitochondrion/Stoichiometry/2.0
type: Stoichiometry
physical entity: Enoyl-[acyl-carrier-protein] reductase, mitochondrial
stoichiometric coefficient: 2.0

Reference/BioCyc CPD-196
type: UnificationXref
id: CPD-196
db: BioCyc

Compound/PW C002009 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Hexadecenoyl-CoA
stoichiometric coefficient: 1.0

Acetyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Acetyl-CoA

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/PubChem-compound 11966197
type: UnificationXref
id: 11966197
db: PubChem-compound

Compound/PW C001031 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmityl-CoA
stoichiometric coefficient: 1.0

Lauroyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Lauroyl-CoA

Reference/HMDB HMDB0001088
type: UnificationXref
id: HMDB0001088
db: HMDB

Reference/BioCyc 7-METHYL-3-OXOOCTANOYL-COA
type: UnificationXref
id: 7-METHYL-3-OXOOCTANOYL-COA
db: BioCyc

Compound/PW C000143 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Tetradecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Tetradecanoyl-CoA

Rattus norvegicus
type: BioSource
xref: Reference/TAXONOMY 10116

(2E)-Dodecenoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 1066-12-2
xref: Reference/PubChem-compound 45266564
xref: Reference/ChemSpider 26330706
xref: Reference/HMDB HMDB0003712
xref: Reference/BioCyc CPD-7222
xref: Reference/ChEBI CHEBI 57330
xref: Reference/KEGG Compound C03221
chemical formula: C33H56N7O17P3S
molecular weight: 947.2666
structure: ChemicalStructure/PW C001959

Hexanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0002845
xref: Reference/KEGG Compound C05270
xref: Reference/ChemSpider 395736
xref: Reference/CAS 5060-32-2
xref: Reference/PubChem-compound 449118
xref: Reference/ChEBI CHEBI 27540
chemical formula: C27H46N7O17P3S
molecular weight: 865.18835
structure: ChemicalStructure/PW C001719

Reference/BioCyc LAUROYLCOA-CPD
type: UnificationXref
id: LAUROYLCOA-CPD
db: BioCyc

Reference/PubChem-compound 53477508
type: UnificationXref
id: 53477508
db: PubChem-compound

3-Oxohexadecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Oxohexadecanoyl-CoA

Reference/KEGG Compound C00249
type: UnificationXref
id: C00249
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChEBI CHEBI 28276
type: UnificationXref
id: CHEBI:28276
db: ChEBI

3-Hydroxyoctanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Hydroxyoctanoyl-CoA

Compound/PW C001171 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Tetradecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 3130-72-1
type: UnificationXref
id: 3130-72-1
db: CAS

Reference/ChemSpider 389502
type: UnificationXref
id: 389502
db: ChemSpider

Octanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C01944
xref: Reference/ChEBI CHEBI 15533
xref: Reference/HMDB HMDB0001070
xref: Reference/ChemSpider 371
xref: Reference/BioCyc CPD-196
xref: Reference/PubChem-compound 380
xref: Reference/CAS 1264-52-4
chemical formula: C29H50N7O17P3S
molecular weight: 893.21967
structure: ChemicalStructure/PW C000845

Reference/ChemSpider 389501
type: UnificationXref
id: 389501
db: ChemSpider

Reference/ChemSpider 389500
type: UnificationXref
id: 389500
db: ChemSpider

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/ChemSpider 389506
type: UnificationXref
id: 389506
db: ChemSpider

Reference/ChemSpider 389504
type: UnificationXref
id: 389504
db: ChemSpider

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/PubChem-compound 11966160
type: UnificationXref
id: 11966160
db: PubChem-compound

Reference/KEGG Compound C00136
type: UnificationXref
id: C00136
db: KEGG Compound

3-Oxohexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Oxohexanoyl-CoA

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/ChEBI CHEBI 10723
type: UnificationXref
id: CHEBI:10723
db: ChEBI

Reference/ChemSpider 389508
type: UnificationXref
id: 389508
db: ChemSpider

Reference/ChEBI CHEBI 28264
type: UnificationXref
id: CHEBI:28264
db: ChEBI

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Butyryl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 2140-48-9
xref: Reference/ChEBI CHEBI 57371
xref: Reference/ChemSpider 260
xref: Reference/PubChem-compound 265
xref: Reference/KEGG Compound C00136
xref: Reference/BioCyc CPD-12174
xref: Reference/HMDB HMDB0001088
chemical formula: C25H42N7O17P3S
molecular weight: 837.15704
structure: ChemicalStructure/PW C000856

Reference/UniProt F1LPY7
type: UnificationXref
id: F1LPY7
db: UniProt

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/ChemSpider 389510
type: UnificationXref
id: 389510
db: ChemSpider

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/CAS 1264-57-9
type: UnificationXref
id: 1264-57-9
db: CAS

3-Hydroxyhexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Hydroxyhexanoyl-CoA

Reference/UniProt Q5BIZ5
type: UnificationXref
id: Q5BIZ5
db: UniProt

Reference/ChEBI CHEBI 28493
type: UnificationXref
id: CHEBI:28493
db: ChEBI

Reference/CAS 4460-95-1
type: UnificationXref
id: 4460-95-1
db: CAS

Reference/CAS 72059-49-5
type: UnificationXref
id: 72059-49-5
db: CAS

3-Hydroxyhexadecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 27402
xref: Reference/HMDB HMDB0003932
xref: Reference/CAS 35106-50-4
xref: Reference/ChemSpider 389498
xref: Reference/PubChem-compound 440600
xref: Reference/KEGG Compound C05258
chemical formula: C37H66N7O18P3S
molecular weight: 1021.3398
structure: ChemicalStructure/PW C001996

Reference/KEGG Compound C00154
type: UnificationXref
id: C00154
db: KEGG Compound

3-Hydroxytetradecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 27466
xref: Reference/ChemSpider 389500
xref: Reference/HMDB HMDB0003934
xref: Reference/KEGG Compound C05260
xref: Reference/PubChem-compound 440602
chemical formula: C35H62N7O18P3S
molecular weight: 993.3085
structure: ChemicalStructure/PW C001998

3-Oxotetradecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 11966197
xref: Reference/HMDB HMDB0003935
xref: Reference/ChemSpider 10140190
xref: Reference/KEGG Compound C05261
xref: Reference/ChEBI CHEBI 28726
xref: Reference/CAS 122364-86-7
chemical formula: C35H60N7O18P3S
molecular weight: 991.29285
structure: ChemicalStructure/PW C001999

Protein/15541 Mitochondrion/Stoichiometry/4.0
type: Stoichiometry
physical entity: 3-hydroxyacyl-CoA dehydrogenase type-2
stoichiometric coefficient: 4.0

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/CAS 35106-50-4
type: UnificationXref
id: 35106-50-4
db: CAS

Compound/PW C002002 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxydecanoyl-CoA
stoichiometric coefficient: 1.0

Trifunctional enzyme subunit alpha, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Trifunctional enzyme subunit alpha, mitochondrial

Reference/PubChem-compound 16061159
type: UnificationXref
id: 16061159
db: PubChem-compound

Reference/BioCyc CPD-12174
type: UnificationXref
id: CPD-12174
db: BioCyc

ChemicalStructure/PW C002003
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002004
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002005
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002006
type: ChemicalStructure
structure format: SMILES

Acetyl-CoA acyltransferase
type: Complex
component stoichiometry: Protein/15161 Mitochondrion/Stoichiometry/4.0
cellular location: Mitochondrion
component: 3-ketoacyl-CoA thiolase, mitochondrial

Reference/KEGG Compound C02593
type: UnificationXref
id: C02593
db: KEGG Compound

ChemicalStructure/PW C001031
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002000
type: ChemicalStructure
structure format: SMILES

3-Oxohexadecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 34619-89-1
xref: Reference/HMDB HMDB0006402
xref: Reference/ChEBI CHEBI 15491
xref: Reference/ChemSpider 389499
xref: Reference/PubChem-compound 440601
xref: Reference/KEGG Compound C05259
xref: Reference/BioCyc 3-OXOPALMITOYL-COA
chemical formula: C37H64N7O18P3S
molecular weight: 1019.32416
structure: ChemicalStructure/PW C002740

ChemicalStructure/PW C002001
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002002
type: ChemicalStructure
structure format: SMILES

Decanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05274
xref: Reference/CAS 1264-57-9
xref: Reference/HMDB HMDB0006404
xref: Reference/PubChem-compound 440615
xref: Reference/ChEBI CHEBI 28493
xref: Reference/ChemSpider 389510
chemical formula: C31H54N7O17P3S
molecular weight: 921.251
structure: ChemicalStructure/PW C002742

Protein/15156 Mitochondrion/Stoichiometry/4.0
type: Stoichiometry
physical entity: Trifunctional enzyme subunit beta, mitochondrial
stoichiometric coefficient: 4.0

Compound/PW C002000 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxydodecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/CAS 54684-64-9
type: UnificationXref
id: 54684-64-9
db: CAS

Compound/PW C001999 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxotetradecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc 3-OXOPALMITOYL-COA
type: UnificationXref
id: 3-OXOPALMITOYL-COA
db: BioCyc

NAD
type: SmallMolecule
cellular location: Mitochondrion
entity reference: NAD

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/CAS 2140-48-9
type: UnificationXref
id: 2140-48-9
db: CAS

3-Oxodecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Oxodecanoyl-CoA

Reference/CAS 57-10-3
type: UnificationXref
id: 57-10-3
db: CAS

Reference/ChemSpider 26330706
type: UnificationXref
id: 26330706
db: ChemSpider

Reference/PubChem-compound 165436
type: UnificationXref
id: 165436
db: PubChem-compound

3-Hydroxydecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Hydroxydecanoyl-CoA

Enoyl-[acyl-carrier-protein] reductase, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Enoyl-[acyl-carrier-protein] reductase, mitochondrial

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Trifunctional enzyme subunit beta, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Trifunctional enzyme subunit beta, mitochondrial

(2E)-Octenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Octenoyl-CoA

Reference/KEGG Compound C03221
type: UnificationXref
id: C03221
db: KEGG Compound

Compound/PW C002742 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Decanoyl-CoA
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

3-Oxododecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Oxododecanoyl-CoA

Compound/PW C002004 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxyoctanoyl-CoA
stoichiometric coefficient: 1.0

Palmitic acid
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Palmitic acid

Compound/PW C001719 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hexanoyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

(2E)-Dodecenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Dodecenoyl-CoA

Reference/CAS 6245-70-1
type: UnificationXref
id: 6245-70-1
db: CAS

Enoyl-CoA hydratase, mitochondrial
type: ProteinReference
xref: Reference/UniProt P14604
organism: Rattus norvegicus

NADP
type: SmallMolecule
cellular location: Mitochondrion
entity reference: NADP

Reference/ChemSpider 960
type: UnificationXref
id: 960
db: ChemSpider

Protein/15161 Mitochondrion/Stoichiometry/4.0
type: Stoichiometry
physical entity: 3-ketoacyl-CoA thiolase, mitochondrial
stoichiometric coefficient: 4.0

Reference/HMDB HMDB0003571
type: UnificationXref
id: HMDB0003571
db: HMDB

Reference/CAS 1264-52-4
type: UnificationXref
id: 1264-52-4
db: CAS

(2E)-Tetradecenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Tetradecenoyl-CoA

Reference/PubChem-compound 985
type: UnificationXref
id: 985
db: PubChem-compound

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Compound/PW C002006 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxyhexanoyl-CoA
stoichiometric coefficient: 1.0

Trifunctional enzyme subunit beta, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q60587
organism: Rattus norvegicus

Palmityl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Palmityl-CoA

ChemicalStructure/PW C002007
type: ChemicalStructure
structure format: SMILES

Trifunctional enzyme subunit alpha, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q5BIZ5
organism: Rattus norvegicus

ChemicalStructure/PW C002008
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002009
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

ChemicalStructure/PW C002010
type: ChemicalStructure
structure format: SMILES

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C002012
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002013
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Compound/PW C002740 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxohexadecanoyl-CoA
stoichiometric coefficient: 1.0

NADPH
type: SmallMolecule
cellular location: Mitochondrion
entity reference: NADPH

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

(2E)-Decenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Decenoyl-CoA

3-ketoacyl-CoA thiolase, mitochondrial
type: ProteinReference
xref: Reference/UniProt P13437
organism: Rattus norvegicus

ChemicalStructure/PW C001171
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis137213
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction147041
control type: ACTIVATION

ReactionCatalysis137215
type: Catalysis
controller: Acetyl-CoA acyltransferase
controlled: 2.3.1.16
control type: ACTIVATION

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Enoyl-CoA hydratase, mitochondrial
type: Complex
component stoichiometry: Protein/15144 Mitochondrion/Stoichiometry/6.0
cellular location: Mitochondrion
component: Enoyl-CoA hydratase, mitochondrial

ReactionCatalysis137211
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

Reference/PubChem-compound 65113
type: UnificationXref
id: 65113
db: PubChem-compound

Reference/CAS 78303-19-2
type: UnificationXref
id: 78303-19-2
db: CAS

3-Hydroxydodecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Hydroxydodecanoyl-CoA

ReactionCatalysis137218
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction147043
control type: ACTIVATION

Reference/ChemSpider 10140190
type: UnificationXref
id: 10140190
db: ChemSpider

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/ChemSpider 371
type: UnificationXref
id: 371
db: ChemSpider

ReactionCatalysis137224
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

ReactionCatalysis137226
type: Catalysis
controller: 3-hydroxyacyl-CoA dehydrogenase type-2
controlled: Reaction147046
control type: ACTIVATION

ReactionCatalysis137227
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction147046
control type: ACTIVATION

ReactionCatalysis137221
type: Catalysis
controller: Acetyl-CoA acyltransferase
controlled: 2.3.1.16
control type: ACTIVATION

Reference/ChEBI CHEBI 57371
type: UnificationXref
id: CHEBI:57371
db: ChEBI

Reference/UniProt P13437
type: UnificationXref
id: P13437
db: UniProt

ReactionCatalysis137229
type: Catalysis
controller: Acetyl-CoA acyltransferase
controlled: 2.3.1.16
control type: ACTIVATION

Reference/HMDB HMDB0002845
type: UnificationXref
id: HMDB0002845
db: HMDB

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/HMDB HMDB0003934
type: UnificationXref
id: HMDB0003934
db: HMDB

Reference/HMDB HMDB0003935
type: UnificationXref
id: HMDB0003935
db: HMDB

Reference/CAS 5060-32-2
type: UnificationXref
id: 5060-32-2
db: CAS

Reference/HMDB HMDB0003932
type: UnificationXref
id: HMDB0003932
db: HMDB

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000856 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002007 Mitochondrion/Stoichiometry/1.0
right: 3-Oxohexanoyl-CoA
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.16
left: Acetyl-CoA
left: Butyryl-CoA
name: Acetyl-CoA + Butyryl-CoA → 3-Oxohexanoyl-CoA + Coenzyme A
conversion direction: LEFT_TO_RIGHT

Reaction147053
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001144 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002006 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002007 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrion/Stoichiometry/1.0
right: 3-Oxohexanoyl-CoA
right: Hydrogen Ion
right: NADH
spontaneous: false
left: NAD
left: 3-Hydroxyhexanoyl-CoA
name: 3-Hydroxyhexanoyl-CoA + NAD ↔ 3-Oxohexanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

Reference/BioCyc PALMITYL-COA
type: UnificationXref
id: PALMITYL-COA
db: BioCyc

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002008 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002006 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
right: Water
right: (2E)-Hexenoyl-CoA
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxyhexanoyl-CoA
name: 3-Hydroxyhexanoyl-CoA ↔ (2E)-Hexenoyl-CoA + Water
conversion direction: REVERSIBLE

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001719 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002005 Mitochondrion/Stoichiometry/1.0
right: Coenzyme A
right: 3-Oxooctanoyl-CoA
spontaneous: false
EC number: 2.3.1.16
left: Hexanoyl-CoA
left: Acetyl-CoA
name: Acetyl-CoA + Hexanoyl-CoA ↔ 3-Oxooctanoyl-CoA + Coenzyme A
conversion direction: REVERSIBLE

Compound/PW C002013 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Octenoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Hexanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Hexanoyl-CoA

Reference/PubChem-compound 440608
type: UnificationXref
id: 440608
db: PubChem-compound

Reference/PubChem-compound 440606
type: UnificationXref
id: 440606
db: PubChem-compound

Reference/HMDB HMDB0003938
type: UnificationXref
id: HMDB0003938
db: HMDB

ChemicalStructure/PW C001999
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0003939
type: UnificationXref
id: HMDB0003939
db: HMDB

ChemicalStructure/PW C001998
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 380
type: UnificationXref
id: 380
db: PubChem-compound

Reference/PubChem-compound 440604
type: UnificationXref
id: 440604
db: PubChem-compound

Reference/HMDB HMDB0003936
type: UnificationXref
id: HMDB0003936
db: HMDB

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/HMDB HMDB0003937
type: UnificationXref
id: HMDB0003937
db: HMDB

Reference/PubChem-compound 440603
type: UnificationXref
id: 440603
db: PubChem-compound

ChemicalStructure/PW C001996
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 265
type: UnificationXref
id: 265
db: PubChem-compound

Reference/PubChem-compound 440602
type: UnificationXref
id: 440602
db: PubChem-compound

Reference/PubChem-compound 440601
type: UnificationXref
id: 440601
db: PubChem-compound

Reference/PubChem-compound 440600
type: UnificationXref
id: 440600
db: PubChem-compound

Protein/15150 Mitochondrion/Stoichiometry/4.0
type: Stoichiometry
physical entity: Trifunctional enzyme subunit alpha, mitochondrial
stoichiometric coefficient: 4.0

Reference/HMDB HMDB0003941
type: UnificationXref
id: HMDB0003941
db: HMDB

Reference/HMDB HMDB0003942
type: UnificationXref
id: HMDB0003942
db: HMDB

Reference/HMDB HMDB0003940
type: UnificationXref
id: HMDB0003940
db: HMDB

Reference/HMDB HMDB0001521
type: UnificationXref
id: HMDB0001521
db: HMDB

Reference/HMDB HMDB0003945
type: UnificationXref
id: HMDB0003945
db: HMDB

Reference/HMDB HMDB0003946
type: UnificationXref
id: HMDB0003946
db: HMDB

Reference/HMDB HMDB0003943
type: UnificationXref
id: HMDB0003943
db: HMDB

Reference/HMDB HMDB0003944
type: UnificationXref
id: HMDB0003944
db: HMDB

Reaction147049
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002004 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002005 Mitochondrion/Stoichiometry/1.0
right: Hydrogen Ion
right: 3-Oxooctanoyl-CoA
right: NADH
spontaneous: false
left: NAD
left: 3-Hydroxyoctanoyl-CoA
name: 3-Hydroxyoctanoyl-CoA + NAD ↔ 3-Oxooctanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002013 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002004 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
right: Water
right: (2E)-Octenoyl-CoA
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxyoctanoyl-CoA
name: 3-Hydroxyoctanoyl-CoA ↔ (2E)-Octenoyl-CoA + Water
conversion direction: REVERSIBLE

Hydrogen Ion
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Hydrogen Ion

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000845 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002003 Mitochondrion/Stoichiometry/1.0
right: Coenzyme A
right: 3-Oxodecanoyl-CoA
spontaneous: false
EC number: 2.3.1.16
left: Octanoyl-CoA
left: Acetyl-CoA
name: Acetyl-CoA + Octanoyl-CoA ↔ 3-Oxodecanoyl-CoA + Coenzyme A
conversion direction: REVERSIBLE

Reaction147046
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002002 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002003 Mitochondrion/Stoichiometry/1.0
right: Hydrogen Ion
right: 3-Oxodecanoyl-CoA
right: NADH
spontaneous: false
left: NAD
left: 3-Hydroxydecanoyl-CoA
name: 3-Hydroxydecanoyl-CoA + NAD ↔ 3-Oxodecanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

3.1.2.22
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001031 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000145 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
right: Coenzyme A
right: Palmitic acid
spontaneous: false
EC number: 3.1.2.22
left: Water
left: Palmityl-CoA
name: Palmityl-CoA + Water → Coenzyme A + Palmitic acid
conversion direction: LEFT_TO_RIGHT

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002002 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002012 Mitochondrion/Stoichiometry/1.0
right: Water
right: (2E)-Decenoyl-CoA
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxydecanoyl-CoA
name: 3-Hydroxydecanoyl-CoA ↔ (2E)-Decenoyl-CoA + Water
conversion direction: REVERSIBLE

1.3.1.38
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001031 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002009 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Mitochondrion/Stoichiometry/1.0
right: Palmityl-CoA
right: NADP
spontaneous: false
EC number: 1.3.1.38
left: NADPH
left: (2E)-Hexadecenoyl-CoA
name: (2E)-Hexadecenoyl-CoA + NADPH → NADP + Palmityl-CoA
conversion direction: LEFT_TO_RIGHT

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002742 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002001 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
right: 3-Oxododecanoyl-CoA
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.16
left: Decanoyl-CoA
left: Acetyl-CoA
name: Acetyl-CoA + Decanoyl-CoA → 3-Oxododecanoyl-CoA + Coenzyme A
conversion direction: LEFT_TO_RIGHT

1.3.1.38
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000143 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002010 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001171 Mitochondrion/Stoichiometry/1.0
right: Tetradecanoyl-CoA
right: NADP
spontaneous: false
EC number: 1.3.1.38
left: NADPH
left: (2E)-Tetradecenoyl-CoA
name: (2E)-Tetradecenoyl-CoA + NADPH → NADP + Tetradecanoyl-CoA
conversion direction: LEFT_TO_RIGHT

Reaction147043
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002001 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002000 Mitochondrion/Stoichiometry/1.0
right: 3-Oxododecanoyl-CoA
right: Hydrogen Ion
right: NADH
spontaneous: false
left: NAD
left: 3-Hydroxydodecanoyl-CoA
name: 3-Hydroxydodecanoyl-CoA + NAD ↔ 3-Oxododecanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

1.3.1.38
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001959 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001928 Mitochondrion/Stoichiometry/1.0
right: Lauroyl-CoA
right: NADP
spontaneous: false
EC number: 1.3.1.38
left: (2E)-Dodecenoyl-CoA
left: NADPH
name: (2E)-Dodecenoyl-CoA + NADPH → Lauroyl-CoA + NADP
conversion direction: LEFT_TO_RIGHT

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001959 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002000 Mitochondrion/Stoichiometry/1.0
right: (2E)-Dodecenoyl-CoA
right: Water
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxydodecanoyl-CoA
name: 3-Hydroxydodecanoyl-CoA ↔ (2E)-Dodecenoyl-CoA + Water
conversion direction: REVERSIBLE

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001928 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001999 Mitochondrion/Stoichiometry/1.0
right: 3-Oxotetradecanoyl-CoA
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.16
left: Lauroyl-CoA
left: Acetyl-CoA
name: Acetyl-CoA + Lauroyl-CoA → 3-Oxotetradecanoyl-CoA + Coenzyme A
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

1.3.1.38
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002742 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002012 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Mitochondrion/Stoichiometry/1.0
right: Decanoyl-CoA
right: NADP
spontaneous: false
EC number: 1.3.1.38
left: NADPH
left: (2E)-Decenoyl-CoA
name: (2E)-Decenoyl-CoA + NADPH → Decanoyl-CoA + NADP
conversion direction: LEFT_TO_RIGHT

Reaction147041
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001144 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001998 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001999 Mitochondrion/Stoichiometry/1.0
right: 3-Oxotetradecanoyl-CoA
right: Hydrogen Ion
right: NADH
spontaneous: false
left: NAD
left: 3-Hydroxytetradecanoyl-CoA
name: 3-Hydroxytetradecanoyl-CoA + NAD ↔ 3-Oxotetradecanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

1.3.1.38
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002013 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000845 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Mitochondrion/Stoichiometry/1.0
right: Octanoyl-CoA
right: NADP
spontaneous: false
EC number: 1.3.1.38
left: NADPH
left: (2E)-Octenoyl-CoA
name: (2E)-Octenoyl-CoA + NADPH → NADP + Octanoyl-CoA
conversion direction: LEFT_TO_RIGHT

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001998 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002010 Mitochondrion/Stoichiometry/1.0
right: Water
right: (2E)-Tetradecenoyl-CoA
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxytetradecanoyl-CoA
name: 3-Hydroxytetradecanoyl-CoA ↔ (2E)-Tetradecenoyl-CoA + Water
conversion direction: REVERSIBLE

1.3.1.38
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002008 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001719 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Mitochondrion/Stoichiometry/1.0
right: Hexanoyl-CoA
right: NADP
spontaneous: false
EC number: 1.3.1.38
left: NADPH
left: (2E)-Hexenoyl-CoA
name: (2E)-Hexenoyl-CoA + NADPH → Hexanoyl-CoA + NADP
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis137203
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

Reference/BioCyc K-HEXANOYL-COA
type: UnificationXref
id: K-HEXANOYL-COA
db: BioCyc

Enoyl-CoA hydratase, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Enoyl-CoA hydratase, mitochondrial

ReactionCatalysis137205
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction147037
control type: ACTIVATION

Trifunctional enzyme, mitochondrial
type: Complex
component stoichiometry: Protein/15150 Mitochondrion/Stoichiometry/4.0
component stoichiometry: Protein/15156 Mitochondrion/Stoichiometry/4.0
cellular location: Mitochondrion
component: Trifunctional enzyme subunit beta, mitochondrial
component: Trifunctional enzyme subunit alpha, mitochondrial

Reference/HMDB HMDB0003949
type: UnificationXref
id: HMDB0003949
db: HMDB

Reference/HMDB HMDB0003948
type: UnificationXref
id: HMDB0003948
db: HMDB

ReactionCatalysis137207
type: Catalysis
controller: Acetyl-CoA acyltransferase
controlled: 2.3.1.16
control type: ACTIVATION

ChemicalStructure/PW C002740
type: ChemicalStructure
structure format: SMILES

Compound/PW C002008 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Hexenoyl-CoA
stoichiometric coefficient: 1.0

Reference/PubChem-compound 45266564
type: UnificationXref
id: 45266564
db: PubChem-compound

3-Hydroxytetradecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Hydroxytetradecanoyl-CoA

ChemicalStructure/PW C002742
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0003712
type: UnificationXref
id: HMDB0003712
db: HMDB

Reference/ChEBI CHEBI 61526
type: UnificationXref
id: CHEBI:61526
db: ChEBI

2.3.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000940 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002740 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001171 Mitochondrion/Stoichiometry/1.0
right: 3-Oxohexadecanoyl-CoA
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.16
left: Tetradecanoyl-CoA
left: Acetyl-CoA
name: Acetyl-CoA + Tetradecanoyl-CoA ↔ 3-Oxohexadecanoyl-CoA + Coenzyme A
conversion direction: REVERSIBLE

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Reaction147037
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001144 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002740 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001996 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Mitochondrion/Stoichiometry/1.0
right: 3-Oxohexadecanoyl-CoA
right: Hydrogen Ion
right: NADH
spontaneous: false
left: NAD
left: 3-Hydroxyhexadecanoyl-CoA
name: 3-Hydroxyhexadecanoyl-CoA + NAD ↔ 3-Oxohexadecanoyl-CoA + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

4.2.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001996 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002009 Mitochondrion/Stoichiometry/1.0
right: Water
right: (2E)-Hexadecenoyl-CoA
spontaneous: false
EC number: 4.2.1.17
left: 3-Hydroxyhexadecanoyl-CoA
name: 3-Hydroxyhexadecanoyl-CoA ↔ (2E)-Hexadecenoyl-CoA + Water
conversion direction: REVERSIBLE

Palmitic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 985
xref: Reference/KEGG Compound C00249
xref: Reference/ChemSpider 960
xref: Reference/ChEBI CHEBI 15756
xref: Reference/BioCyc CPD-8475
xref: Reference/CAS 57-10-3
xref: Reference/HMDB HMDB0000220
chemical formula: C16H32O2
molecular weight: 256.24023
structure: ChemicalStructure/PW C000145

Reference/ChemSpider 260
type: UnificationXref
id: 260
db: ChemSpider

Mitochondrion
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005739

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H29N7O17P3
molecular weight: 744.08325
structure: ChemicalStructure/PW C000143

Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase Deficiency (LCHAD)
type: Pathway
pathway order: PathwayEnzymeReaction/2114003
pathway order: PathwayEnzymeReaction/2114002
pathway order: PathwayEnzymeReaction/2114001
pathway order: PathwayEnzymeReaction/2114000
pathway order: PathwayEnzymeReaction/2113995
pathway order: PathwayEnzymeReaction/2114007
pathway order: PathwayEnzymeReaction/2113996
pathway order: PathwayEnzymeReaction/2114006
pathway order: PathwayEnzymeReaction/2114005
pathway order: PathwayEnzymeReaction/2113994
pathway order: PathwayEnzymeReaction/2114004
pathway order: PathwayEnzymeReaction/2113999
pathway order: PathwayEnzymeReaction/2113997
pathway order: PathwayEnzymeReaction/2114009
pathway order: PathwayEnzymeReaction/2113998
pathway order: PathwayEnzymeReaction/2114008
pathway order: PathwayEnzymeReaction/2114021
pathway order: PathwayEnzymeReaction/2114020
pathway order: PathwayEnzymeReaction/2114014
pathway order: PathwayEnzymeReaction/2114013
pathway order: PathwayEnzymeReaction/2114012
pathway order: PathwayEnzymeReaction/2114011
pathway order: PathwayEnzymeReaction/2114018
pathway order: PathwayEnzymeReaction/2114017
pathway order: PathwayEnzymeReaction/2114016
pathway order: PathwayEnzymeReaction/2114015
pathway order: PathwayEnzymeReaction/2114019
pathway order: PathwayEnzymeReaction/2114010
pathway component: ReactionCatalysis137213
pathway component: ReactionCatalysis137215
pathway component: ReactionCatalysis137211
pathway component: ReactionCatalysis137218
pathway component: ReactionCatalysis137224
pathway component: ReactionCatalysis137389
pathway component: ReactionCatalysis137226
pathway component: ReactionCatalysis137227
pathway component: ReactionCatalysis137385
pathway component: ReactionCatalysis137386
pathway component: ReactionCatalysis137221
pathway component: ReactionCatalysis137387
pathway component: ReactionCatalysis137229
pathway component: ReactionCatalysis137384
pathway component: 2.3.1.16
pathway component: Reaction147053
pathway component: 4.2.1.17
pathway component: ReactionCatalysis137235
pathway component: ReactionCatalysis137237
pathway component: ReactionCatalysis137232
pathway component: ReactionCatalysis137234
pathway component: Reaction147049
pathway component: ReactionCatalysis137392
pathway component: Reaction147046
pathway component: 3.1.2.22
pathway component: 1.3.1.38
pathway component: Reaction147043
pathway component: ReactionCatalysis137390
pathway component: Reaction147041
pathway component: ReactionCatalysis137391
pathway component: ReactionCatalysis137246
pathway component: ReactionCatalysis137203
pathway component: ReactionCatalysis137248
pathway component: ReactionCatalysis137205
pathway component: ReactionCatalysis137244
pathway component: ReactionCatalysis137245
pathway component: ReactionCatalysis137207

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/ChEBI CHEBI 15521
type: UnificationXref
id: CHEBI:15521
db: ChEBI

Reference/UniProt Q60587
type: UnificationXref
id: Q60587
db: UniProt

Reference/ChEBI CHEBI 15525
type: UnificationXref
id: CHEBI:15525
db: ChEBI

3-Hydroxyhexanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003942
xref: Reference/CAS 79171-47-4
xref: Reference/KEGG Compound C05268
xref: Reference/PubChem-compound 11966160
xref: Reference/ChEBI CHEBI 28276
xref: Reference/ChemSpider 10140154
chemical formula: C27H46N7O18P3S
molecular weight: 881.1833
structure: ChemicalStructure/PW C002006

3-Oxohexanoyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc K-HEXANOYL-COA
xref: Reference/HMDB HMDB0003943
xref: Reference/ChEBI CHEBI 27648
xref: Reference/ChemSpider 389508
xref: Reference/CAS 19774-86-8
xref: Reference/KEGG Compound C05269
xref: Reference/PubChem-compound 440610
chemical formula: C27H44N7O18P3S
molecular weight: 879.16766
structure: ChemicalStructure/PW C002007

(2E)-Hexenoyl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5280765
xref: Reference/KEGG Compound C05271
xref: Reference/ChemSpider 4444331
xref: Reference/HMDB HMDB0003944
xref: Reference/ChEBI CHEBI 28706
xref: Reference/CAS 10018-93-6
chemical formula: C27H44N7O17P3S
molecular weight: 863.1727
structure: ChemicalStructure/PW C002008

(2E)-Hexadecenoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003945
xref: Reference/ChEBI CHEBI 61526
xref: Reference/KEGG Compound C05272
xref: Reference/PubChem-compound 46173176
xref: Reference/ChemSpider 26332261
xref: Reference/CAS 4460-95-1
chemical formula: C37H64N7O17P3S
molecular weight: 1003.3292
structure: ChemicalStructure/PW C002009

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

(2E)-Tetradecenoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChemSpider 4444333
xref: Reference/ChEBI CHEBI 27721
xref: Reference/HMDB HMDB0003946
xref: Reference/CAS 38795-33-4
xref: Reference/KEGG Compound C05273
xref: Reference/PubChem-compound 5280767
chemical formula: C35H60N7O17P3S
molecular weight: 975.2979
structure: ChemicalStructure/PW C002010

Water
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Water

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

(2E)-Decenoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05275
xref: Reference/BioCyc T2-DECENOYL-COA
xref: Reference/ChemSpider 4444334
xref: Reference/ChEBI CHEBI 10723
xref: Reference/CAS 10018-95-8
xref: Reference/HMDB HMDB0003948
xref: Reference/PubChem-compound 5280768
chemical formula: C31H52N7O17P3S
molecular weight: 919.23535
structure: ChemicalStructure/PW C002012

(2E)-Octenoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChemSpider 4444335
xref: Reference/KEGG Compound C05276
xref: Reference/ChEBI CHEBI 27537
xref: Reference/HMDB HMDB0003949
xref: Reference/PubChem-compound 5280769
xref: Reference/CAS 10018-94-7
chemical formula: C29H48N7O17P3S
molecular weight: 891.20404
structure: ChemicalStructure/PW C002013

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Reference/ChEBI CHEBI 28726
type: UnificationXref
id: CHEBI:28726
db: ChEBI

Reference/ChemSpider 10140154
type: UnificationXref
id: 10140154
db: ChemSpider

Enoyl-[acyl-carrier-protein] reductase, mitochondrial
type: ProteinReference
xref: Reference/UniProt F1LPY7
organism: Rattus norvegicus

Reference/ChEBI CHEBI 15533
type: UnificationXref
id: CHEBI:15533
db: ChEBI

Reference/ChEBI CHEBI 15532
type: UnificationXref
id: CHEBI:15532
db: ChEBI

3-hydroxyacyl-CoA dehydrogenase type-2
type: ProteinReference
xref: Reference/UniProt Q9QYD4
organism: Rattus norvegicus

Reference/ChEBI CHEBI 28706
type: UnificationXref
id: CHEBI:28706
db: ChEBI

Reference/PubChem-compound 440615
type: UnificationXref
id: 440615
db: PubChem-compound

Reference/ChEBI CHEBI 57330
type: UnificationXref
id: CHEBI:57330
db: ChEBI

Reference/CAS 1763-10-6
type: UnificationXref
id: 1763-10-6
db: CAS

Reference/UniProt P14604
type: UnificationXref
id: P14604
db: UniProt

Reference/BioCyc TETRADECANOYL-COA
type: UnificationXref
id: TETRADECANOYL-COA
db: BioCyc

(2E)-Hexadecenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Hexadecenoyl-CoA

Reference/KEGG Compound C05259
type: UnificationXref
id: C05259
db: KEGG Compound

Reference/PubChem-compound 440610
type: UnificationXref
id: 440610
db: PubChem-compound

Reference/KEGG Compound C05258
type: UnificationXref
id: C05258
db: KEGG Compound

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C05264
type: UnificationXref
id: C05264
db: KEGG Compound

Compound/PW C040034 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Reference/KEGG Compound C05263
type: UnificationXref
id: C05263
db: KEGG Compound

Reference/KEGG Compound C05266
type: UnificationXref
id: C05266
db: KEGG Compound

Reference/KEGG Compound C05265
type: UnificationXref
id: C05265
db: KEGG Compound

Reference/KEGG Compound C05260
type: UnificationXref
id: C05260
db: KEGG Compound

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C05262
type: UnificationXref
id: C05262
db: KEGG Compound

ChemicalStructure/PW C000145
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCC(O)=O

Reference/ChEBI CHEBI 27868
type: UnificationXref
id: CHEBI:27868
db: ChEBI

Reference/KEGG Compound C05261
type: UnificationXref
id: C05261
db: KEGG Compound

Reference/CAS 19774-86-8
type: UnificationXref
id: 19774-86-8
db: CAS

3-Hydroxyhexadecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Hydroxyhexadecanoyl-CoA

Tetradecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 3130-72-1
xref: Reference/HMDB HMDB0001521
xref: Reference/KEGG Compound C02593
xref: Reference/ChEBI CHEBI 15532
xref: Reference/ChemSpider 58623
xref: Reference/PubChem-compound 65113
xref: Reference/BioCyc TETRADECANOYL-COA
chemical formula: C35H62N7O17P3S
molecular weight: 977.3136
structure: ChemicalStructure/PW C001171

Reference/HMDB HMDB0000220
type: UnificationXref
id: HMDB0000220
db: HMDB

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Palmitoyl-protein thioesterase 1
type: ProteinReference
xref: Reference/UniProt A0JN20
organism: Rattus norvegicus

Reference/KEGG Compound C05268
type: UnificationXref
id: C05268
db: KEGG Compound

(2E)-Hexenoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: (2E)-Hexenoyl-CoA

Reference/KEGG Compound C05267
type: UnificationXref
id: C05267
db: KEGG Compound

Reference/KEGG Compound C05269
type: UnificationXref
id: C05269
db: KEGG Compound

Reference/KEGG Compound C05275
type: UnificationXref
id: C05275
db: KEGG Compound

Reference/KEGG Compound C05274
type: UnificationXref
id: C05274
db: KEGG Compound

Reference/KEGG Compound C05276
type: UnificationXref
id: C05276
db: KEGG Compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/KEGG Compound C05271
type: UnificationXref
id: C05271
db: KEGG Compound

3-ketoacyl-CoA thiolase, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: 3-ketoacyl-CoA thiolase, mitochondrial

Reference/KEGG Compound C05270
type: UnificationXref
id: C05270
db: KEGG Compound

Reference/KEGG Compound C05273
type: UnificationXref
id: C05273
db: KEGG Compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/KEGG Compound C05272
type: UnificationXref
id: C05272
db: KEGG Compound

Reference/CAS 34619-89-1
type: UnificationXref
id: 34619-89-1
db: CAS

Reference/ChEBI CHEBI 15756
type: UnificationXref
id: CHEBI:15756
db: ChEBI

Compound/PW C001144 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Palmityl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 15667
xref: Reference/ChemSpider 14902
xref: Reference/HMDB HMDB0001338
xref: Reference/ChEBI CHEBI 15525
xref: Reference/KEGG Compound C00154
xref: Reference/CAS 1763-10-6
xref: Reference/BioCyc PALMITYL-COA
chemical formula: C37H66N7O17P3S
molecular weight: 1005.34485
structure: ChemicalStructure/PW C001031

3-hydroxyacyl-CoA dehydrogenase type-2
type: Protein
cellular location: Mitochondrion
entity reference: 3-hydroxyacyl-CoA dehydrogenase type-2

3-Hydroxydodecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 72059-49-5
xref: Reference/ChemSpider 389501
xref: Reference/ChEBI CHEBI 27668
xref: Reference/KEGG Compound C05262
xref: Reference/HMDB HMDB0003936
xref: Reference/PubChem-compound 440603
chemical formula: C33H58N7O18P3S
molecular weight: 965.27716
structure: ChemicalStructure/PW C002000

Reference/GENE ONTOLOGY GO 0005739
type: UnificationXref
id: GO:0005739
db: GENE ONTOLOGY

3-Oxododecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05263
xref: Reference/ChemSpider 389502
xref: Reference/CAS 78303-19-2
xref: Reference/ChEBI CHEBI 27868
xref: Reference/PubChem-compound 440604
xref: Reference/HMDB HMDB0003937
chemical formula: C33H56N7O18P3S
molecular weight: 963.26154
structure: ChemicalStructure/PW C002001

Reference/ChEBI CHEBI 27721
type: UnificationXref
id: CHEBI:27721
db: ChEBI

3-Hydroxydecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05264
xref: Reference/ChEBI CHEBI 28325
xref: Reference/CAS 6245-70-1
xref: Reference/ChemSpider 17220838
xref: Reference/HMDB HMDB0003938
xref: Reference/PubChem-compound 16061159
chemical formula: C31H54N7O18P3S
molecular weight: 937.2459
structure: ChemicalStructure/PW C002002

3-Oxodecanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05265
xref: Reference/ChEBI CHEBI 28528
xref: Reference/ChemSpider 389504
xref: Reference/PubChem-compound 440606
xref: Reference/HMDB HMDB0003939
xref: Reference/CAS 50411-91-1
chemical formula: C31H52N7O18P3S
molecular weight: 935.2302
structure: ChemicalStructure/PW C002003

3-Hydroxyoctanoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 28632
xref: Reference/KEGG Compound C05266
xref: Reference/HMDB HMDB0003940
xref: Reference/CAS 79171-48-5
xref: Reference/PubChem-compound 53477508
chemical formula: C29H50N7O18P3S
molecular weight: 909.2146
structure: ChemicalStructure/PW C002004

Decanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Decanoyl-CoA

3-Oxooctanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003941
xref: Reference/ChemSpider 389506
xref: Reference/PubChem-compound 440608
xref: Reference/BioCyc 7-METHYL-3-OXOOCTANOYL-COA
xref: Reference/ChEBI CHEBI 28264
xref: Reference/KEGG Compound C05267
xref: Reference/CAS 54684-64-9
chemical formula: C29H48N7O18P3S
molecular weight: 907.1989
structure: ChemicalStructure/PW C002005

Reference/HMDB HMDB0001338
type: UnificationXref
id: HMDB0001338
db: HMDB

Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChemSpider 58623
type: UnificationXref
id: 58623
db: ChemSpider

Reference/CAS 10018-95-8
type: UnificationXref
id: 10018-95-8
db: CAS

Reference/CAS 79171-47-4
type: UnificationXref
id: 79171-47-4
db: CAS

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/TAXONOMY 10116
type: UnificationXref
id: 10116
db: TAXONOMY

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Trans-2-enoyl-CoA reductase, mitochondrial
type: Complex
component stoichiometry: Protein/15546 Mitochondrion/Stoichiometry/2.0
cellular location: Mitochondrion
component: Enoyl-[acyl-carrier-protein] reductase, mitochondrial

ChemicalStructure/PW C000845
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5280765
type: UnificationXref
id: 5280765
db: PubChem-compound

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Reference/ChEBI CHEBI 28528
type: UnificationXref
id: CHEBI:28528
db: ChEBI

Reference/PubChem-compound 5280769
type: UnificationXref
id: 5280769
db: PubChem-compound

Reference/CAS 50411-91-1
type: UnificationXref
id: 50411-91-1
db: CAS

Reference/SMPDB SMP0120827
type: UnificationXref
id: SMP0120827
db: SMPDB

Reference/PubChem-compound 5280767
type: UnificationXref
id: 5280767
db: PubChem-compound

Reference/PubChem-compound 5280768
type: UnificationXref
id: 5280768
db: PubChem-compound

Reference/UniProt A0JN20
type: UnificationXref
id: A0JN20
db: UniProt

Reference/ChemSpider 395736
type: UnificationXref
id: 395736
db: ChemSpider

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/BioCyc CPD-8475
type: UnificationXref
id: CPD-8475
db: BioCyc

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

ChemicalStructure/PW C000856
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 28632
type: UnificationXref
id: CHEBI:28632
db: ChEBI

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/ChEBI CHEBI 27668
type: UnificationXref
id: CHEBI:27668
db: ChEBI

Reference/CAS 79171-48-5
type: UnificationXref
id: 79171-48-5
db: CAS

Reference/ChEBI CHEBI 27540
type: UnificationXref
id: CHEBI:27540
db: ChEBI

Reference/KEGG Compound C01944
type: UnificationXref
id: C01944
db: KEGG Compound

Compound/PW C001959 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Dodecenoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 14902
type: UnificationXref
id: 14902
db: ChemSpider

Coenzyme A
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Coenzyme A

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

3-Oxotetradecanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: 3-Oxotetradecanoyl-CoA

Reference/PathWhiz PW122088
type: UnificationXref
id: PW122088
db: PathWhiz

Reference/ChEBI CHEBI 27537
type: UnificationXref
id: CHEBI:27537
db: ChEBI

ReactionCatalysis137392
type: Catalysis
controller: Palmitoyl-protein thioesterase 1
controlled: 3.1.2.22
control type: ACTIVATION

Palmitoyl-protein thioesterase 1
type: Protein
cellular location: Mitochondrion
entity reference: Palmitoyl-protein thioesterase 1

ReactionCatalysis137390
type: Catalysis
controller: Trans-2-enoyl-CoA reductase, mitochondrial
controlled: 1.3.1.38
control type: ACTIVATION

ReactionCatalysis137391
type: Catalysis
controller: Trans-2-enoyl-CoA reductase, mitochondrial
controlled: 1.3.1.38
control type: ACTIVATION

ChemicalStructure/PW C001928
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C01832
type: UnificationXref
id: C01832
db: KEGG Compound

Octanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Octanoyl-CoA

Reference/PubChem-compound 449118
type: UnificationXref
id: 449118
db: PubChem-compound

Reference/CAS 122364-86-7
type: UnificationXref
id: 122364-86-7
db: CAS

Compound/PW C002001 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxododecanoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 27402
type: UnificationXref
id: CHEBI:27402
db: ChEBI

Reference/ChEBI CHEBI 27648
type: UnificationXref
id: CHEBI:27648
db: ChEBI

Compound/PW C001998 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxytetradecanoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C000845 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Octanoyl-CoA
stoichiometric coefficient: 1.0

NADH
type: SmallMolecule
cellular location: Mitochondrion
entity reference: NADH

Reference/BioCyc T2-DECENOYL-COA
type: UnificationXref
id: T2-DECENOYL-COA
db: BioCyc

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Reference/ChemSpider 145018
type: UnificationXref
id: 145018
db: ChemSpider

Reference/CAS 10018-93-6
type: UnificationXref
id: 10018-93-6
db: CAS

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/ChEBI CHEBI 28325
type: UnificationXref
id: CHEBI:28325
db: ChEBI

Compound/PW C000146 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Butyryl-CoA
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Butyryl-CoA

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

ReactionCatalysis137389
type: Catalysis
controller: Trans-2-enoyl-CoA reductase, mitochondrial
controlled: 1.3.1.38
control type: ACTIVATION

Reference/UniProt Q9QYD4
type: UnificationXref
id: Q9QYD4
db: UniProt

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

ReactionCatalysis137385
type: Catalysis
controller: Trans-2-enoyl-CoA reductase, mitochondrial
controlled: 1.3.1.38
control type: ACTIVATION

ReactionCatalysis137386
type: Catalysis
controller: Trans-2-enoyl-CoA reductase, mitochondrial
controlled: 1.3.1.38
control type: ACTIVATION

ReactionCatalysis137387
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

Protein/15144 Mitochondrion/Stoichiometry/6.0
type: Stoichiometry
physical entity: Enoyl-CoA hydratase, mitochondrial
stoichiometric coefficient: 6.0

Reference/BioCyc CPD-7222
type: UnificationXref
id: CPD-7222
db: BioCyc

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/ChEBI CHEBI 15491
type: UnificationXref
id: CHEBI:15491
db: ChEBI

Reference/ChemSpider 389499
type: UnificationXref
id: 389499
db: ChemSpider

Reference/ChemSpider 389498
type: UnificationXref
id: 389498
db: ChemSpider

Reference/ChEBI CHEBI 27466
type: UnificationXref
id: CHEBI:27466
db: ChEBI

ReactionCatalysis137384
type: Catalysis
controller: Trans-2-enoyl-CoA reductase, mitochondrial
controlled: 1.3.1.38
control type: ACTIVATION

Reference/ChemSpider 26332261
type: UnificationXref
id: 26332261
db: ChemSpider

Compound/PW C002003 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxodecanoyl-CoA
stoichiometric coefficient: 1.0

ReactionCatalysis137235
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction147049
control type: ACTIVATION

Reference/ChemSpider 4444333
type: UnificationXref
id: 4444333
db: ChemSpider

Reference/ChemSpider 4444334
type: UnificationXref
id: 4444334
db: ChemSpider

ChemicalStructure/PW C001719
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis137237
type: Catalysis
controller: Acetyl-CoA acyltransferase
controlled: 2.3.1.16
control type: ACTIVATION

Reference/ChemSpider 4444335
type: UnificationXref
id: 4444335
db: ChemSpider

ReactionCatalysis137232
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

Reference/ChemSpider 4444331
type: UnificationXref
id: 4444331
db: ChemSpider

Compound/PW C001996 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Hydroxyhexadecanoyl-CoA
stoichiometric coefficient: 1.0

ReactionCatalysis137234
type: Catalysis
controller: 3-hydroxyacyl-CoA dehydrogenase type-2
controlled: Reaction147049
control type: ACTIVATION

Compound/PW C002010 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2E)-Tetradecenoyl-CoA
stoichiometric coefficient: 1.0

Reference/PubChem-compound 46173176
type: UnificationXref
id: 46173176
db: PubChem-compound

Reference/CAS 6244-92-4
type: UnificationXref
id: 6244-92-4
db: CAS

ChemicalStructure/PW C001959
type: ChemicalStructure
structure format: SMILES

Reference/CAS 10018-94-7
type: UnificationXref
id: 10018-94-7
db: CAS

ReactionCatalysis137246
type: Catalysis
controller: Trifunctional enzyme, mitochondrial
controlled: Reaction147053
control type: ACTIVATION

Reference/CAS 1066-12-2
type: UnificationXref
id: 1066-12-2
db: CAS

Reference/PubChem-compound 15667
type: UnificationXref
id: 15667
db: PubChem-compound

ReactionCatalysis137248
type: Catalysis
controller: Acetyl-CoA acyltransferase
controlled: 2.3.1.16
control type: ACTIVATION

ReactionCatalysis137244
type: Catalysis
controller: Enoyl-CoA hydratase, mitochondrial
controlled: 4.2.1.17
control type: ACTIVATION

ReactionCatalysis137245
type: Catalysis
controller: 3-hydroxyacyl-CoA dehydrogenase type-2
controlled: Reaction147053
control type: ACTIVATION

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Compound/PW C002005 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Oxooctanoyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C000721 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS