Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/ChemSpider 392615
type: UnificationXref
id: 392615
db: ChemSpider

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

α-D-Glucose 1,6-bisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18148
xref: Reference/CAS 10139-18-1
xref: Reference/ChemSpider 74362
xref: Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
xref: Reference/PubChem-compound 82400
xref: Reference/HMDB HMDB0003514
xref: Reference/KEGG Compound C00660
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C001910

Reference/BioCyc GLUCURONATE
type: UnificationXref
id: GLUCURONATE
db: BioCyc

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Reference/CAS 88070-93-3
type: UnificationXref
id: 88070-93-3
db: CAS

Reference/CAS 6556-12-3
type: UnificationXref
id: 6556-12-3
db: CAS

Reference/PubChem-compound 6133
type: UnificationXref
id: 6133
db: PubChem-compound

Reference/KEGG Compound C00208
type: UnificationXref
id: C00208
db: KEGG Compound

Compound/PW C001851 Extracellular Space/Stoichiometry/4.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 4.0

Protein/15738 Cytosol/Stoichiometry/8.0
type: Stoichiometry
physical entity: UTP--glucose-1-phosphate uridylyltransferase
stoichiometric coefficient: 8.0

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Pancreatic alpha-amylase
type: Protein
cellular location: Extracellular Space
entity reference: Pancreatic alpha-amylase

Reference/CAS 53188-23-1
type: UnificationXref
id: 53188-23-1
db: CAS

Reference/PubChem-compound 53477771
type: UnificationXref
id: 53477771
db: PubChem-compound

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Compound/PW C001405 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Isovalerylglucuronide
stoichiometric coefficient: 1.0

Reference/UniProt O70199
type: UnificationXref
id: O70199
db: UniProt

UDP-glucuronosyltransferase 2B1
type: Protein
cellular location: Endoplasmic Reticulum
entity reference: UDP-glucuronosyltransferase 2B1

Reference/ChemSpider 5743
type: UnificationXref
id: 5743
db: ChemSpider

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

NADH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADH

UTP--glucose-1-phosphate uridylyltransferase
type: Complex
component stoichiometry: Protein/15738 Cytosol/Stoichiometry/8.0
cellular location: Cytosol
component: UTP--glucose-1-phosphate uridylyltransferase

Reference/ChEBI CHEBI 17200
type: UnificationXref
id: CHEBI:17200
db: ChEBI

Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
type: UnificationXref
id: ALPHA-GLUCOSE-16-BISPHOSPHATE
db: BioCyc

Reference/PubChem-compound 439177
type: UnificationXref
id: 439177
db: PubChem-compound

Reference/ChemSpider 9166684
type: UnificationXref
id: 9166684
db: ChemSpider

SubPathwayInteraction108666
type: Interaction
name: SubPathway108666Reaction
name: SubPathwayReaction
participant: Glucose 6-phosphate

ChemicalStructure/PW C001083
type: ChemicalStructure
structure format: SMILES

Sucrase-isomaltase, intestinal
type: Protein
cellular location: Cytosol
entity reference: Sucrase-isomaltase, intestinal

Reference/ChEBI CHEBI 28102
type: UnificationXref
id: CHEBI:28102
db: ChEBI

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Uridine 5'-diphosphate

Reference/BioCyc CPD0-971
type: UnificationXref
id: CPD0-971
db: BioCyc

Reference/PubChem-compound 53477679
type: UnificationXref
id: 53477679
db: PubChem-compound

Reference/BioCyc UDP-GLUCURONATE
type: UnificationXref
id: UDP-GLUCURONATE
db: BioCyc

Reference/PubChem-compound 6031
type: UnificationXref
id: 6031
db: PubChem-compound

Reference/UniProt P09875
type: UnificationXref
id: P09875
db: UniProt

Reference/CAS 133-89-1
type: UnificationXref
id: 133-89-1
db: CAS

Reference/ChemSpider 704
type: UnificationXref
id: 704
db: ChemSpider

Compound/PW C001083 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000152
type: UnificationXref
id: PW000152
db: PathWhiz

Reference/KEGG Compound C00103
type: UnificationXref
id: C00103
db: KEGG Compound

Compound/PW C000746 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucuronic acid
stoichiometric coefficient: 1.0

Compound/PW C001144 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 2.0

Reference/PubChem-compound 439165
type: UnificationXref
id: 439165
db: PubChem-compound

Glycogen phosphorylase, liver form
type: Protein
cellular location: Cytosol
entity reference: Glycogen phosphorylase, liver form

Rattus norvegicus
type: BioSource
xref: Reference/TAXONOMY 10116

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine 5'-diphosphate

Compound/PW C000192 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine triphosphate
stoichiometric coefficient: 1.0

Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (Glycogen debranching enzyme, glycogen storage disease type III) (Predicted), isoform CRA_a
type: Protein
cellular location: Cytosol
entity reference: Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (Glycogen debranching enzyme, glycogen storage disease type III) (Predicted), isoform CRA_a

Uridine diphosphate glucuronic acid
type: SmallMoleculeReference
xref: Reference/BioCyc UDP-GLUCURONATE
xref: Reference/CAS 2616-64-0
xref: Reference/PubChem-compound 17473
xref: Reference/HMDB HMDB0000935
xref: Reference/ChEBI CHEBI 17200
xref: Reference/ChemSpider 16522
xref: Reference/KEGG Compound C00167
chemical formula: C15H22N2O18P2
molecular weight: 580.0343
structure: ChemicalStructure/PW C000746

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5768
type: UnificationXref
id: 5768
db: ChemSpider

Reference/ChemSpider 389526
type: UnificationXref
id: 389526
db: ChemSpider

Reference/CAS 59-56-3
type: UnificationXref
id: 59-56-3
db: CAS

Glyceric acid 1,3-biphosphate
type: SmallMoleculeReference
xref: Reference/CAS 1981-49-3
xref: Reference/ChemSpider 663
xref: Reference/BioCyc DPG
xref: Reference/HMDB HMDB0001270
xref: Reference/KEGG Compound C00236
xref: Reference/PubChem-compound 683
chemical formula: C3H8O10P2
molecular weight: 265.95926
structure: ChemicalStructure/PW C000983

Reference/PubChem-compound 444791
type: UnificationXref
id: 444791
db: PubChem-compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/KEGG Compound C00236
type: UnificationXref
id: C00236
db: KEGG Compound

Reference/ChemSpider 388311
type: UnificationXref
id: 388311
db: ChemSpider

Compound/PW C000170 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00597
type: UnificationXref
id: C00597
db: KEGG Compound

Compound/PW C000193 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucose
stoichiometric coefficient: 1.0

Sucrase-isomaltase, intestinal
type: ProteinReference
xref: Reference/UniProt P23739
organism: Rattus norvegicus

Phosphoglucomutase 2-like 1
type: ProteinReference
xref: Reference/UniProt D3Z955
organism: Rattus norvegicus

D-Fructose
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-535
xref: Reference/ChEBI CHEBI 28645
xref: Reference/ChemSpider 388775
xref: Reference/PubChem-compound 439709
xref: Reference/KEGG Compound C02336
xref: Reference/HMDB HMDB0000660
xref: Reference/CAS 53188-23-1
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000517

Reference/UniProt P09811
type: UnificationXref
id: P09811
db: UniProt

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/UniProt F1LQ84
type: UnificationXref
id: F1LQ84
db: UniProt

Reference/BioCyc Beta-D-Glucuronides
type: UnificationXref
id: Beta-D-Glucuronides
db: BioCyc

Transport8039
type: Transport
participant stoichiometry: Compound/PW C000517 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: D-Fructose
spontaneous: false
left: D-Fructose
name: D-Fructose (→) Transport: Rattus norvegicus, Extracellular Space to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Protein/15740 Cytosol/Stoichiometry/6.0
type: Stoichiometry
physical entity: UDP-glucose 6-dehydrogenase
stoichiometric coefficient: 6.0

Compound/PW C000177 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sucrose
stoichiometric coefficient: 1.0

Reference/ChemSpider 388322
type: UnificationXref
id: 388322
db: ChemSpider

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Pancreatic alpha-amylase
type: ProteinReference
xref: Reference/UniProt P00689
organism: Rattus norvegicus

Transport8041
type: Transport
participant stoichiometry: Compound/PW C000605 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000605 Extracellular Space/Stoichiometry/1.0
right: Glycogen
spontaneous: false
left: Glycogen
name: Glycogen (→) Transport: Rattus norvegicus, Extracellular Space to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Phosphoglucomutase 2-like 1
type: Protein
cellular location: Cytosol
entity reference: Phosphoglucomutase 2-like 1

Glycogen [starch] synthase, liver
type: ProteinReference
xref: Reference/UniProt Q99MF8
organism: Rattus norvegicus

Transport8042
type: Transport
participant stoichiometry: Compound/PW C000107 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000107 Cytosol/Stoichiometry/1.0
right: D-Maltose
spontaneous: false
left: D-Maltose
name: D-Maltose (→) Transport: Rattus norvegicus, Extracellular Space to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

α-D-Glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003345
xref: Reference/ChemSpider 71358
xref: Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
xref: Reference/PubChem-compound 79025
xref: Reference/ChEBI CHEBI 17925
xref: Reference/CAS 492-62-6
xref: Reference/KEGG Compound C00267
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C001851

Reference/BioCyc GLC-1-P
type: UnificationXref
id: GLC-1-P
db: BioCyc

1,4-alpha-glucan-branching enzyme
type: ProteinReference
organism: Rattus norvegicus

Compound/PW C000201 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

Transport8040
type: Transport
participant stoichiometry: Compound/PW C001851 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Cytosol/Stoichiometry/1.0
right: α-D-Glucose
spontaneous: false
left: α-D-Glucose
name: α-D-Glucose (→) Transport: Rattus norvegicus, Extracellular Space to Rattus norvegicus, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Glycogen
type: SmallMoleculeReference
xref: Reference/BioCyc CPD0-971
xref: Reference/KEGG Compound C00182
xref: Reference/PubChem-compound 439177
xref: Reference/HMDB HMDB0000757
xref: Reference/CAS 9005-79-2
xref: Reference/ChEBI CHEBI 28087
xref: Reference/ChemSpider 388322
chemical formula: C24H42O21
molecular weight: 666.22186
structure: ChemicalStructure/PW C000605

Reference/ChemSpider 388775
type: UnificationXref
id: 388775
db: ChemSpider

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/HMDB HMDB0002091
type: UnificationXref
id: HMDB0002091
db: HMDB

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/BioCyc FRUCTOSE-6P
type: UnificationXref
id: FRUCTOSE-6P
db: BioCyc

Reference/KEGG Compound C00015
type: UnificationXref
id: C00015
db: KEGG Compound

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Extracellular Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005615

α-D-Glucose
type: SmallMolecule
cellular location: Extracellular Space
entity reference: α-D-Glucose

Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (Glycogen debranching enzyme, glycogen storage disease type III) (Predicted), isoform CRA_a
type: ProteinReference
xref: Reference/UniProt D4AEH9
organism: Rattus norvegicus

Glucose-6-phosphate isomerase
type: Protein
cellular location: Cytosol
entity reference: Glucose-6-phosphate isomerase

Reference/KEGG Compound C00029
type: UnificationXref
id: C00029
db: KEGG Compound

Reference/PubChem-compound 62698
type: UnificationXref
id: 62698
db: PubChem-compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00267
type: UnificationXref
id: C00267
db: KEGG Compound

Reference/KEGG Compound C02336
type: UnificationXref
id: C02336
db: KEGG Compound

Reference/HMDB HMDB0001586
type: UnificationXref
id: HMDB0001586
db: HMDB

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0003403
type: UnificationXref
id: HMDB0003403
db: HMDB

Reference/HMDB HMDB0000258
type: UnificationXref
id: HMDB0000258
db: HMDB

ChemicalStructure/PW C000177
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 28087
type: UnificationXref
id: CHEBI:28087
db: ChEBI

Compound/PW C001851 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Reference/PubChem-compound 10991489
type: UnificationXref
id: 10991489
db: PubChem-compound

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Glucokinase
type: Protein
cellular location: Cytosol
entity reference: Glucokinase

Dextrin
type: SmallMoleculeReference
xref: Reference/ChemSpider 56445
xref: Reference/KEGG Compound C00721
xref: Reference/PubChem-compound 62698
xref: Reference/HMDB HMDB0006857
xref: Reference/CAS 9004-53-9
chemical formula: C18H32O16
molecular weight: 504.16904
structure: ChemicalStructure/PW C002975

Isovalerylglucuronide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 137383
xref: Reference/ChemSpider 121058
xref: Reference/HMDB HMDB0002091
xref: Reference/BioCyc Beta-D-Glucuronides
xref: Reference/CAS 88070-93-3
chemical formula: C11H18O8
molecular weight: 278.10016
structure: ChemicalStructure/PW C001405

Reference/KEGG Compound C00167
type: UnificationXref
id: C00167
db: KEGG Compound

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Sucrose
type: SmallMolecule
cellular location: Cytosol
entity reference: Sucrose

Compound/PW C000193 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucose
stoichiometric coefficient: 1.0

Compound/PW C000201 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

Reference/CAS 9004-53-9
type: UnificationXref
id: 9004-53-9
db: CAS

Uridine 5'-diphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17659
xref: Reference/PubChem-compound 6031
xref: Reference/CAS 58-98-0
xref: Reference/HMDB HMDB0000295
xref: Reference/KEGG Compound C00015
xref: Reference/ChemSpider 5809
xref: Reference/BioCyc UDP
chemical formula: C9H14N2O12P2
molecular weight: 404.0022
structure: ChemicalStructure/PW C000201

Isovalerylglucuronide
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Isovalerylglucuronide

Reference/BioCyc UTP
type: UnificationXref
id: UTP
db: BioCyc

Reference/ChemSpider 5903
type: UnificationXref
id: 5903
db: ChemSpider

3-Phosphoglyceric acid
type: SmallMoleculeReference
xref: Reference/BioCyc G3P
xref: Reference/PubChem-compound 724
xref: Reference/ChEBI CHEBI 17050
xref: Reference/ChemSpider 704
xref: Reference/CAS 820-11-1
xref: Reference/KEGG Compound C00597
xref: Reference/HMDB HMDB0000807
chemical formula: C3H7O7P
molecular weight: 185.99294
structure: ChemicalStructure/PW C000644

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChEBI CHEBI 16077
type: UnificationXref
id: CHEBI:16077
db: ChEBI

Reference/ChEBI CHEBI 4170
type: UnificationXref
id: CHEBI:4170
db: ChEBI

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/KEGG Compound C00182
type: UnificationXref
id: C00182
db: KEGG Compound

Reference/UniProt Q9QWR1
type: UnificationXref
id: Q9QWR1
db: UniProt

Reference/CAS 492-62-6
type: UnificationXref
id: 492-62-6
db: CAS

Compound/PW C001851 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Reference/ChemSpider 16522
type: UnificationXref
id: 16522
db: ChemSpider

NAD
type: SmallMolecule
cellular location: Cytosol
entity reference: NAD

Reference/ChEBI CHEBI 18148
type: UnificationXref
id: CHEBI:18148
db: ChEBI

Reference/UniProt P06760
type: UnificationXref
id: P06760
db: UniProt

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C002021 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Fructose 6-phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc DPG
type: UnificationXref
id: DPG
db: BioCyc

Reference/ChEBI CHEBI 16084
type: UnificationXref
id: CHEBI:16084
db: ChEBI

Compound/PW C000721 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 2.0

Compound/PW C001207 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 1-phosphate
stoichiometric coefficient: 1.0

Compound/PW C001851 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00191
type: UnificationXref
id: C00191
db: KEGG Compound

Reference/ChemSpider 663
type: UnificationXref
id: 663
db: ChemSpider

α-D-Glucose
type: SmallMolecule
cellular location: Cytosol
entity reference: α-D-Glucose

Reference/CAS 9005-82-7
type: UnificationXref
id: 9005-82-7
db: CAS

Reference/ChEBI CHEBI 17050
type: UnificationXref
id: CHEBI:17050
db: ChEBI

Amylose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003403
xref: Reference/CAS 9005-82-7
xref: Reference/KEGG Compound C00718
xref: Reference/PubChem-compound 53477771
xref: Reference/ChEBI CHEBI 28102
chemical formula: C14H26O11
molecular weight: 370.14752
structure: ChemicalStructure/PW C001872

Reference/HMDB HMDB0000163
type: UnificationXref
id: HMDB0000163
db: HMDB

Reference/UniProt Q99MF8
type: UnificationXref
id: Q99MF8
db: UniProt

3-Phosphoglyceric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 3-Phosphoglyceric acid

Reference/HMDB HMDB0000286
type: UnificationXref
id: HMDB0000286
db: HMDB

Reference/HMDB HMDB0000285
type: UnificationXref
id: HMDB0000285
db: HMDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

D-Maltose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 47937
xref: Reference/BioCyc MALTOSE
xref: Reference/KEGG Compound C00208
xref: Reference/ChemSpider 9166684
xref: Reference/HMDB HMDB0000163
xref: Reference/CAS 69-79-4
xref: Reference/PubChem-compound 10991489
chemical formula: C12H22O11
molecular weight: 342.1162
structure: ChemicalStructure/PW C000107

Reference/PubChem-compound 724
type: UnificationXref
id: 724
db: PubChem-compound

Compound/PW C000746 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucuronic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/CAS 58-98-0
type: UnificationXref
id: 58-98-0
db: CAS

UDP-glucose 6-dehydrogenase
type: Complex
component stoichiometry: Protein/15740 Cytosol/Stoichiometry/6.0
cellular location: Cytosol
component: UDP-glucose 6-dehydrogenase

Reference/KEGG Compound C00075
type: UnificationXref
id: C00075
db: KEGG Compound

UTP--glucose-1-phosphate uridylyltransferase
type: Protein
cellular location: Cytosol
entity reference: UTP--glucose-1-phosphate uridylyltransferase

Reference/PathWhiz PW122100
type: UnificationXref
id: PW122100
db: PathWhiz

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0000295
type: UnificationXref
id: HMDB0000295
db: HMDB

Reference/ChemSpider 5809
type: UnificationXref
id: 5809
db: ChemSpider

UDP-glucose 6-dehydrogenase
type: Protein
cellular location: Cytosol
entity reference: UDP-glucose 6-dehydrogenase

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

SubPathwayInteraction108667
type: Interaction
name: SubPathwayReaction
name: SubPathway108667Reaction
participant: Glucose 6-phosphate

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/KEGG Compound C00089
type: UnificationXref
id: C00089
db: KEGG Compound

Glucose 1-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001586
xref: Reference/PubChem-compound 439165
xref: Reference/CAS 59-56-3
xref: Reference/BioCyc GLC-1-P
xref: Reference/ChEBI CHEBI 16077
xref: Reference/KEGG Compound C00103
xref: Reference/ChemSpider 388311
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001207

Compound/Generic20 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Alcohol
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00092
type: UnificationXref
id: C00092
db: KEGG Compound

Reference/ChemSpider 71358
type: UnificationXref
id: 71358
db: ChemSpider

Reference/BioCyc G3P
type: UnificationXref
id: G3P
db: BioCyc

Reference/UniProt P17711
type: UnificationXref
id: P17711
db: UniProt

Reference/HMDB HMDB0001270
type: UnificationXref
id: HMDB0001270
db: HMDB

D-Fructose
type: SmallMolecule
cellular location: Extracellular Space
entity reference: D-Fructose

Reference/ChEBI CHEBI 47937
type: UnificationXref
id: CHEBI:47937
db: ChEBI

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/CAS 56-73-5
type: UnificationXref
id: 56-73-5
db: CAS

Compound/PW C000107 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Maltose
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003345
type: UnificationXref
id: HMDB0003345
db: HMDB

Hexokinase-2
type: ProteinReference
xref: Reference/UniProt Q9QWR1
organism: Rattus norvegicus

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/HMDB HMDB0006857
type: UnificationXref
id: HMDB0006857
db: HMDB

Glucose-6-phosphate isomerase
type: ProteinReference
xref: Reference/UniProt Q6P6V0
organism: Rattus norvegicus

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

ChemicalStructure/PW C000193
type: ChemicalStructure
structure format: SMILES

β-D-Fructose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: β-D-Fructose 6-phosphate

ChemicalStructure/PW C000192
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Compound/PW C001851 Extracellular Space/Stoichiometry/3.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 3.0

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Compound/PW C001420 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/UniProt D3Z955
type: UnificationXref
id: D3Z955
db: UniProt

ChemicalStructure/PW C002021
type: ChemicalStructure
structure format: SMILES

Compound/PW C001207 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 1-phosphate
stoichiometric coefficient: 1.0

Sucrase-isomaltase, intestinal
type: Protein
cellular location: Extracellular Space
entity reference: Sucrase-isomaltase, intestinal

Reference/UniProt P38652
type: UnificationXref
id: P38652
db: UniProt

Reference/CAS 820-11-1
type: UnificationXref
id: 820-11-1
db: CAS

ChemicalStructure/PW C000082
type: ChemicalStructure
structure format: SMILES

Hexokinase-2
type: Protein
cellular location: Cytosol
entity reference: Hexokinase-2

Reference/BioCyc SUCROSE
type: UnificationXref
id: SUCROSE
db: BioCyc

Reference/BioCyc CPD-535
type: UnificationXref
id: CPD-535
db: BioCyc

Glucose-6-phosphate isomerase
type: Complex
component stoichiometry: Protein/16127 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Glucose-6-phosphate isomerase

Compound/PW C000983 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glyceric acid 1,3-biphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Mucopolysaccharidosis VII. Sly Syndrome
type: Pathway
pathway order: PathwayEnzymeReaction/2115059
pathway order: PathwayEnzymeReaction/2115058
pathway order: PathwayEnzymeReaction/2115057
pathway order: PathwayEnzymeReaction/2115056
pathway order: PathwayTransport/2115064
pathway order: PathwayTransport/2115063
pathway order: PathwayTransport/2115066
pathway order: PathwayTransport/2115065
pathway order: PathwayEnzymeReaction/2115051
pathway order: PathwayEnzymeReaction/2115050
pathway order: PathwayEnzymeReaction/2115055
pathway order: PathwayEnzymeReaction/2115054
pathway order: PathwayEnzymeReaction/2115053
pathway order: PathwayEnzymeReaction/2115052
pathway order: PathwayEnzymeReaction/2115048
pathway order: PathwayEnzymeReaction/2115047
pathway order: PathwayEnzymeReaction/2115046
pathway order: PathwayEnzymeReaction/2115045
pathway order: PathwayEnzymeReaction/2115049
pathway order: PathwaySubPathway/108666
pathway order: PathwaySubPathway/108667
pathway order: PathwayEnzymeReaction/2115062
pathway order: PathwayEnzymeReaction/2115061
pathway order: PathwayEnzymeReaction/2115060
pathway order: PathwayEnzymeReaction/2115044
pathway order: PathwayEnzymeReaction/2115043
pathway component: ReactionCatalysis138226
pathway component: ReactionCatalysis138225
pathway component: ReactionCatalysis138228
pathway component: ReactionCatalysis138227
pathway component: 2.4.1.1
pathway component: ReactionCatalysis138224
pathway component: 2.4.1.17
pathway component: ReactionCatalysis138223
pathway component: 3.2.1.31
pathway component: ReactionCatalysis138229
pathway component: 2.7.1.1
pathway component: 5.3.1.9
pathway component: Reaction147959
pathway component: ReactionCatalysis137444
pathway component: ReactionCatalysis138237
pathway component: ReactionCatalysis137445
pathway component: ReactionCatalysis138236
pathway component: ReactionCatalysis137446
pathway component: ReactionCatalysis138238
pathway component: ReactionCatalysis138233
pathway component: ReactionCatalysis138232
pathway component: 2.7.1.106
pathway component: ReactionCatalysis138235
pathway component: ReactionCatalysis137443
pathway component: 5.4.2.2
pathway component: ReactionCatalysis138234
pathway component: 2.4.1.11
pathway component: 2.4.1.18
pathway component: Transport8039
pathway component: Reaction147964
pathway component: 3.2.1.1
pathway component: Reaction147966
pathway component: Reaction147967
pathway component: Reaction147968
pathway component: Reaction147969
pathway component: Transport8041
pathway component: Transport8042
pathway component: 1.1.1.22
pathway component: 2.7.7.9
pathway component: Glycolysis
pathway component: 2.7.1.2
pathway component: ReactionCatalysis138231
pathway component: Gluconeogenesis
pathway component: ReactionCatalysis138230
pathway component: Transport8040
xref: Reference/PathWhiz PW122100
xref: Reference/SMPDB SMP0120839
organism: Rattus norvegicus

Reference/PubChem-compound 439709
type: UnificationXref
id: 439709
db: PubChem-compound

Reference/CAS 2616-64-0
type: UnificationXref
id: 2616-64-0
db: CAS

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/CAS 1981-49-3
type: UnificationXref
id: 1981-49-3
db: CAS

Reference/CAS 10139-18-1
type: UnificationXref
id: 10139-18-1
db: CAS

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108666
pathway component: SubPathwayInteraction108666
xref: Reference/SMPDB SMP0000040
xref: Reference/PathWhiz PW000146
name: SubPathway

Isovalerylglucuronide
type: SmallMolecule
cellular location: Lysosome
entity reference: Isovalerylglucuronide

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/HMDB HMDB0000660
type: UnificationXref
id: HMDB0000660
db: HMDB

Glycogen [starch] synthase, liver
type: Protein
cellular location: Cytosol
entity reference: Glycogen [starch] synthase, liver

Lysosome
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005764

Alcohol
type: SmallMolecule
cellular location: Lysosome
entity reference: Alcohol

Reference/KEGG Compound C05345
type: UnificationXref
id: C05345
db: KEGG Compound

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/HMDB HMDB0001401
type: UnificationXref
id: HMDB0001401
db: HMDB

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

ReactionCatalysis137444
type: Catalysis
controller: Phosphoglucomutase-1
controlled: 5.4.2.2
control type: ACTIVATION

ReactionCatalysis137445
type: Catalysis
controller: UTP--glucose-1-phosphate uridylyltransferase
controlled: 2.7.7.9
control type: ACTIVATION

ReactionCatalysis137446
type: Catalysis
controller: UDP-glucose 6-dehydrogenase
controlled: 1.1.1.22
control type: ACTIVATION

Reference/ChEBI CHEBI 15713
type: UnificationXref
id: CHEBI:15713
db: ChEBI

ReactionCatalysis137443
type: Catalysis
controller: Glucokinase
controlled: 2.7.1.2
control type: ACTIVATION

Pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyrophosphate

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

ChemicalStructure/PW C001405
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5988
type: UnificationXref
id: 5988
db: PubChem-compound

ChemicalStructure/PW C002975
type: ChemicalStructure
structure format: SMILES

Compound/PW C000644 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Phosphoglyceric acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 137383
type: UnificationXref
id: 137383
db: PubChem-compound

Amylose
type: SmallMolecule
cellular location: Cytosol
entity reference: Amylose

ChemicalStructure/PW C000201
type: ChemicalStructure
structure format: SMILES

Glycogen phosphorylase, liver form
type: ProteinReference
xref: Reference/UniProt P09811
organism: Rattus norvegicus

Glucose 1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glucose 1-phosphate

Reference/PubChem-compound 683
type: UnificationXref
id: 683
db: PubChem-compound

Uridine diphosphate glucose
type: SmallMoleculeReference
xref: Reference/BioCyc UDP-GLUCOSE
xref: Reference/KEGG Compound C00029
xref: Reference/PubChem-compound 53477679
xref: Reference/CAS 133-89-1
xref: Reference/HMDB HMDB0000286
chemical formula: C15H24N2O17P2
molecular weight: 566.055
structure: ChemicalStructure/PW C000193

Reference/BioCyc UDP-GLUCOSE
type: UnificationXref
id: UDP-GLUCOSE
db: BioCyc

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Uridine triphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6133
xref: Reference/CAS 63-39-8
xref: Reference/ChemSpider 5903
xref: Reference/ChEBI CHEBI 15713
xref: Reference/KEGG Compound C00075
xref: Reference/HMDB HMDB0000285
xref: Reference/BioCyc UTP
chemical formula: C9H15N2O15P3
molecular weight: 483.96854
structure: ChemicalStructure/PW C000192

Reference/SMPDB SMP0000040
type: UnificationXref
id: SMP0000040
db: SMPDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

Reference/GENE ONTOLOGY GO 0005886
type: UnificationXref
id: GO:0005886
db: GENE ONTOLOGY

Reference/GENE ONTOLOGY GO 0005764
type: UnificationXref
id: GO:0005764
db: GENE ONTOLOGY

Compound/PW C000517 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Fructose
stoichiometric coefficient: 1.0

Beta-glucuronidase
type: Protein
cellular location: Lysosome
entity reference: Beta-glucuronidase

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

D-Maltose
type: SmallMolecule
cellular location: Extracellular Space
entity reference: D-Maltose

β-D-Fructose 6-phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440641
xref: Reference/ChemSpider 389526
xref: Reference/ChEBI CHEBI 16084
xref: Reference/KEGG Compound C05345
xref: Reference/BioCyc FRUCTOSE-6P
xref: Reference/HMDB HMDB0003971
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C002021

D-Glucuronic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00191
xref: Reference/BioCyc GLUCURONATE
xref: Reference/ChemSpider 392615
xref: Reference/HMDB HMDB0000127
xref: Reference/PubChem-compound 444791
xref: Reference/ChEBI CHEBI 42717
xref: Reference/CAS 6556-12-3
chemical formula: C6H10O7
molecular weight: 194.04265
structure: ChemicalStructure/PW C000082

Reference/PubChem-compound 17473
type: UnificationXref
id: 17473
db: PubChem-compound

UDP-glucuronosyltransferase 2B1
type: ProteinReference
xref: Reference/UniProt P09875
organism: Rattus norvegicus

Gluconeogenesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway108667
pathway component: SubPathwayInteraction108667
xref: Reference/SMPDB SMP0000128
xref: Reference/PathWhiz PW000152
name: SubPathway

Reference/HMDB HMDB0003971
type: UnificationXref
id: HMDB0003971
db: HMDB

Reference/UniProt P00689
type: UnificationXref
id: P00689
db: UniProt

Beta-glucuronidase
type: ProteinReference
xref: Reference/UniProt P06760
organism: Rattus norvegicus

Compound/PW C000605 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycogen
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000107
type: ChemicalStructure
structure format: SMILES

α-D-Glucose 1,6-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: α-D-Glucose 1,6-bisphosphate

Reference/PubChem-compound 440641
type: UnificationXref
id: 440641
db: PubChem-compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

Compound/PW C000082 Lysosome/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glucuronic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5958
type: UnificationXref
id: 5958
db: PubChem-compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Sucrose
type: SmallMoleculeReference
xref: Reference/BioCyc SUCROSE
xref: Reference/CAS 57-50-1
xref: Reference/HMDB HMDB0000258
xref: Reference/ChemSpider 5768
xref: Reference/KEGG Compound C00089
xref: Reference/PubChem-compound 5988
xref: Reference/ChEBI CHEBI 17992
chemical formula: C12H22O11
molecular weight: 342.1162
structure: ChemicalStructure/PW C000177

Reference/ChemSpider 74362
type: UnificationXref
id: 74362
db: ChemSpider

ChemicalStructure/PW C001207
type: ChemicalStructure
structure format: SMILES

Compound/PW C001405 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Isovalerylglucuronide
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005615
type: UnificationXref
id: GO:0005615
db: GENE ONTOLOGY

Reference/HMDB HMDB0000127
type: UnificationXref
id: HMDB0000127
db: HMDB

Reference/HMDB HMDB0003514
type: UnificationXref
id: HMDB0003514
db: HMDB

Reference/ChEBI CHEBI 17925
type: UnificationXref
id: CHEBI:17925
db: ChEBI

Reference/ChemSpider 56445
type: UnificationXref
id: 56445
db: ChemSpider

Phosphoglucomutase-1
type: ProteinReference
xref: Reference/UniProt P38652
organism: Rattus norvegicus

Reference/SMPDB SMP0000128
type: UnificationXref
id: SMP0000128
db: SMPDB

Endoplasmic Reticulum
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005783

D-Maltose
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Maltose

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/TAXONOMY 10116
type: UnificationXref
id: 10116
db: TAXONOMY

ChemicalStructure/PW C000605
type: ChemicalStructure
structure format: SMILES

Compound/PW C000517 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Fructose
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000807
type: UnificationXref
id: HMDB0000807
db: HMDB

Reference/BioCyc UDP
type: UnificationXref
id: UDP
db: BioCyc

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/ChEBI CHEBI 28645
type: UnificationXref
id: CHEBI:28645
db: ChEBI

Compound/PW C001872 Cytosol/Stoichiometry/4.0
type: Stoichiometry
physical entity: Amylose
stoichiometric coefficient: 4.0

Reference/CAS 9005-79-2
type: UnificationXref
id: 9005-79-2
db: CAS

Reference/KEGG Compound C00718
type: UnificationXref
id: C00718
db: KEGG Compound

UTP--glucose-1-phosphate uridylyltransferase
type: ProteinReference
xref: Reference/UniProt F1LQ84
organism: Rattus norvegicus

Reference/UniProt D4AEH9
type: UnificationXref
id: D4AEH9
db: UniProt

Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00092
xref: Reference/BioCyc GLC-6-P
xref: Reference/HMDB HMDB0001401
xref: Reference/PubChem-compound 5958
xref: Reference/ChemSpider 5743
xref: Reference/CAS 56-73-5
xref: Reference/ChEBI CHEBI 4170
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001083

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Protein/16127 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glucose-6-phosphate isomerase
stoichiometric coefficient: 2.0

Reference/KEGG Compound C00721
type: UnificationXref
id: C00721
db: KEGG Compound

Glycogen
type: SmallMolecule
cellular location: Extracellular Space
entity reference: Glycogen

UDP-glucose 6-dehydrogenase
type: ProteinReference
xref: Reference/UniProt O70199
organism: Rattus norvegicus

Reference/HMDB HMDB0000935
type: UnificationXref
id: HMDB0000935
db: HMDB

Reference/ChEBI CHEBI 42717
type: UnificationXref
id: CHEBI:42717
db: ChEBI

Reference/ChEBI CHEBI 17992
type: UnificationXref
id: CHEBI:17992
db: ChEBI

1.1.1.22
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000193 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000746 Cytosol/Stoichiometry/1.0
right: NADH
right: Uridine diphosphate glucuronic acid
spontaneous: false
EC number: 1.1.1.22
left: NAD
left: Uridine diphosphate glucose
left: Water
name: 2 NAD + Uridine diphosphate glucose + Water → 2 NADH + Uridine diphosphate glucuronic acid
conversion direction: LEFT_TO_RIGHT

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

ChemicalStructure/PW C000983
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C(=O)OP(O)(O)=O

2.7.7.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000192 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000193 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/1.0
right: Pyrophosphate
right: Uridine diphosphate glucose
spontaneous: false
EC number: 2.7.7.9
left: Glucose 1-phosphate
left: Uridine triphosphate
name: Glucose 1-phosphate + Uridine triphosphate → Pyrophosphate + Uridine diphosphate glucose
conversion direction: LEFT_TO_RIGHT

5.4.2.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001207 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001083 Cytosol/Stoichiometry/1.0
right: Glucose 6-phosphate
spontaneous: false
EC number: 5.4.2.2
left: Glucose 1-phosphate
name: Glucose 1-phosphate ↔ Glucose 6-phosphate
conversion direction: REVERSIBLE

2.7.1.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001083 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Glucose 6-phosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.1.2
left: Adenosine triphosphate
left: α-D-Glucose
name: Adenosine triphosphate + α-D-Glucose → Adenosine diphosphate + Glucose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Uridine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine triphosphate

D-Fructose
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Fructose

Phosphoglucomutase-1
type: Protein
cellular location: Cell Membrane
entity reference: Phosphoglucomutase-1

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

ChemicalStructure/PW C001910
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Uridine diphosphate glucuronic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine diphosphate glucuronic acid

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Glucose 1-phosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Glucose 1-phosphate

Compound/PW C001910 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose 1,6-bisphosphate
stoichiometric coefficient: 1.0

Reference/GENE ONTOLOGY GO 0005783
type: UnificationXref
id: GO:0005783
db: GENE ONTOLOGY

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Water
type: SmallMolecule
cellular location: Lysosome
entity reference: Water

Reference/PubChem-compound 82400
type: UnificationXref
id: 82400
db: PubChem-compound

1,4-alpha-glucan-branching enzyme
type: Protein
cellular location: Cytosol
entity reference: 1,4-alpha-glucan-branching enzyme

Reference/CAS 69-79-4
type: UnificationXref
id: 69-79-4
db: CAS

Uridine diphosphate glucose
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Uridine diphosphate glucose

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/BioCyc GLC-6-P
type: UnificationXref
id: GLC-6-P
db: BioCyc

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ReactionCatalysis138226
type: Catalysis
controller: Phosphoglucomutase 2-like 1
controlled: 2.7.1.106
control type: ACTIVATION

ReactionCatalysis138225
type: Catalysis
controller: Sucrase-isomaltase, intestinal
controlled: Reaction147959
control type: ACTIVATION

ReactionCatalysis138228
type: Catalysis
controller: Glycogen [starch] synthase, liver
controlled: 2.4.1.11
control type: ACTIVATION

Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glucose 6-phosphate
name: SubPathwayInput

ReactionCatalysis138227
type: Catalysis
controller: Phosphoglucomutase-1
controlled: 5.4.2.2
control type: ACTIVATION

D-Glucuronic acid
type: SmallMolecule
cellular location: Lysosome
entity reference: D-Glucuronic acid

ReactionCatalysis138224
type: Catalysis
controller: Glucose-6-phosphate isomerase
controlled: 5.3.1.9
control type: ACTIVATION

ReactionCatalysis138223
type: Catalysis
controller: Hexokinase-2
controlled: 2.7.1.1
control type: ACTIVATION

Reference/PathWhiz PW000146
type: UnificationXref
id: PW000146
db: PathWhiz

Uridine diphosphate glucose
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine diphosphate glucose

Uridine diphosphate glucuronic acid
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Uridine diphosphate glucuronic acid

ChemicalStructure/PW C000644
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C(O)=O

Dextrin
type: SmallMolecule
cellular location: Extracellular Space
entity reference: Dextrin

ReactionCatalysis138229
type: Catalysis
controller: 1,4-alpha-glucan-branching enzyme
controlled: 2.4.1.18
control type: ACTIVATION

2.7.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002021 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: β-D-Fructose 6-phosphate
spontaneous: false
EC number: 2.7.1.1
left: D-Fructose
left: Adenosine triphosphate
name: Adenosine triphosphate + D-Fructose → Adenosine diphosphate + β-D-Fructose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

5.3.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002021 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001083 Cytosol/Stoichiometry/1.0
right: Glucose 6-phosphate
spontaneous: false
EC number: 5.3.1.9
left: β-D-Fructose 6-phosphate
name: β-D-Fructose 6-phosphate ↔ Glucose 6-phosphate
conversion direction: REVERSIBLE

Alcohol
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 30879

Reaction147959
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000177 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: Sucrose
right: Water
spontaneous: false
left: D-Fructose
left: α-D-Glucose
name: D-Fructose + α-D-Glucose ← Sucrose + Water
conversion direction: RIGHT_TO_LEFT

Compound/PW C002975 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dextrin
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 30879
type: UnificationXref
id: CHEBI:30879
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Cell Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005886

ReactionCatalysis138237
type: Catalysis
controller: UDP-glucuronosyltransferase 2B1
controlled: 2.4.1.17
control type: ACTIVATION

ReactionCatalysis138236
type: Catalysis
controller: Glycogen phosphorylase, liver form
controlled: 2.4.1.1
control type: ACTIVATION

Reference/ChemSpider 121058
type: UnificationXref
id: 121058
db: ChemSpider

ReactionCatalysis138238
type: Catalysis
controller: Beta-glucuronidase
controlled: 3.2.1.31
control type: ACTIVATION

ReactionCatalysis138233
type: Catalysis
controller: Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (Glycogen debranching enzyme, glycogen storage disease type III) (Predicted), isoform CRA_a
controlled: Reaction147967
control type: ACTIVATION

ReactionCatalysis138232
type: Catalysis
controller: Sucrase-isomaltase, intestinal
controlled: Reaction147966
control type: ACTIVATION

2.7.1.106
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000644 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000983 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001910 Cytosol/Stoichiometry/1.0
right: α-D-Glucose 1,6-bisphosphate
right: 3-Phosphoglyceric acid
spontaneous: false
EC number: 2.7.1.106
left: Glucose 1-phosphate
left: Glyceric acid 1,3-biphosphate
name: Glucose 1-phosphate + Glyceric acid 1,3-biphosphate → 3-Phosphoglyceric acid + α-D-Glucose 1,6-bisphosphate
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc MALTOSE
type: UnificationXref
id: MALTOSE
db: BioCyc

ReactionCatalysis138235
type: Catalysis
controller: Amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (Glycogen debranching enzyme, glycogen storage disease type III) (Predicted), isoform CRA_a
controlled: Reaction147969
control type: ACTIVATION

5.4.2.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000193 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cell Membrane/Stoichiometry/1.0
right: Glucose 1-phosphate
spontaneous: false
EC number: 5.4.2.2
left: Uridine diphosphate glucose
name: Uridine diphosphate glucose → Glucose 1-phosphate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis138234
type: Catalysis
controller: Sucrase-isomaltase, intestinal
controlled: Reaction147968
control type: ACTIVATION

2.4.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000193 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001872 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000201 Cytosol/Stoichiometry/1.0
right: Amylose
right: Uridine 5'-diphosphate
spontaneous: false
EC number: 2.4.1.11
left: Uridine diphosphate glucose
name: Uridine diphosphate glucose → Amylose + Uridine 5'-diphosphate
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

2.4.1.18
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001872 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000605 Cytosol/Stoichiometry/1.0
right: Glycogen
spontaneous: false
EC number: 2.4.1.18
left: Amylose
name: Amylose → Glycogen
conversion direction: LEFT_TO_RIGHT

Reaction147964
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001851 Extracellular Space/Stoichiometry/4.0
participant stoichiometry: Compound/PW C000605 Extracellular Space/Stoichiometry/1.0
right: Glycogen
spontaneous: false
left: α-D-Glucose
name: 4 α-D-Glucose → Glycogen
conversion direction: LEFT_TO_RIGHT

3.2.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002975 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000605 Extracellular Space/Stoichiometry/1.0
right: Dextrin
spontaneous: false
EC number: 3.2.1.1
left: Glycogen
name: Glycogen → Dextrin
conversion direction: LEFT_TO_RIGHT

Glyceric acid 1,3-biphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glyceric acid 1,3-biphosphate

Reaction147966
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002975 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Extracellular Space/Stoichiometry/3.0
right: α-D-Glucose
spontaneous: false
left: Dextrin
name: Dextrin → 3 α-D-Glucose
conversion direction: LEFT_TO_RIGHT

Reaction147967
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001872 Cytosol/Stoichiometry/4.0
participant stoichiometry: Compound/PW C000605 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Cytosol/Stoichiometry/2.0
right: Glycogen
right: α-D-Glucose
spontaneous: false
left: Amylose
name: 4 Amylose → Glycogen + 2 α-D-Glucose
conversion direction: LEFT_TO_RIGHT

Reaction147968
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000107 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Cytosol/Stoichiometry/2.0
right: α-D-Glucose
spontaneous: false
left: D-Maltose
name: D-Maltose → 2 α-D-Glucose
conversion direction: LEFT_TO_RIGHT

Reaction147969
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000107 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851 Cytosol/Stoichiometry/2.0
right: α-D-Glucose
spontaneous: false
left: D-Maltose
name: D-Maltose → 2 α-D-Glucose
conversion direction: LEFT_TO_RIGHT

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Phosphoglucomutase-1
type: Protein
cellular location: Cytosol
entity reference: Phosphoglucomutase-1

ChemicalStructure/PW C001872
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 79025
type: UnificationXref
id: 79025
db: PubChem-compound

ReactionCatalysis138231
type: Catalysis
controller: Pancreatic alpha-amylase
controlled: 3.2.1.1
control type: ACTIVATION

ReactionCatalysis138230
type: Catalysis
controller: Sucrase-isomaltase, intestinal
controlled: Reaction147964
control type: ACTIVATION

Compound/PW C000605 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycogen
stoichiometric coefficient: 1.0

2.4.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001872 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000605 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Amylose
right: Glucose 1-phosphate
spontaneous: false
EC number: 2.4.1.1
left: Phosphate
left: Glycogen
name: Glycogen + Phosphate → Amylose + Glucose 1-phosphate
conversion direction: LEFT_TO_RIGHT

2.4.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000201 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000746 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001405 Endoplasmic Reticulum/Stoichiometry/1.0
right: Isovalerylglucuronide
right: Uridine 5'-diphosphate
spontaneous: false
EC number: 2.4.1.17
left: Uridine diphosphate glucuronic acid
name: Uridine diphosphate glucuronic acid → Isovalerylglucuronide + Uridine 5'-diphosphate
conversion direction: LEFT_TO_RIGHT

3.2.1.31
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000082 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001405 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Lysosome/Stoichiometry/1.0
participant stoichiometry: Compound/Generic20 Lysosome/Stoichiometry/1.0
right: D-Glucuronic acid
right: Alcohol
spontaneous: false
EC number: 3.2.1.31
left: Water
left: Isovalerylglucuronide
name: Isovalerylglucuronide + Water → Alcohol + D-Glucuronic acid
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000746
type: ChemicalStructure
structure format: SMILES

Compound/PW C001872 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Amylose
stoichiometric coefficient: 1.0

Compound/PW C000107 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Maltose
stoichiometric coefficient: 1.0

Glycogen
type: SmallMolecule
cellular location: Cytosol
entity reference: Glycogen

Reference/UniProt P23739
type: UnificationXref
id: P23739
db: UniProt

Reference/CAS 63-39-8
type: UnificationXref
id: 63-39-8
db: CAS

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/CAS 57-50-1
type: UnificationXref
id: 57-50-1
db: CAS

Reference/ChEBI CHEBI 17659
type: UnificationXref
id: CHEBI:17659
db: ChEBI

Reference/KEGG Compound C00660
type: UnificationXref
id: C00660
db: KEGG Compound

Reference/HMDB HMDB0000757
type: UnificationXref
id: HMDB0000757
db: HMDB

ChemicalStructure/PW C000517
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)[C@H](O)[C@H](O)C(=O)CO

Reference/UniProt Q6P6V0
type: UnificationXref
id: Q6P6V0
db: UniProt

ChemicalStructure/PW C001851
type: ChemicalStructure
structure format: SMILES

Glucokinase
type: ProteinReference
xref: Reference/UniProt P17711
organism: Rattus norvegicus

Reference/SMPDB SMP0120839
type: UnificationXref
id: SMP0120839
db: SMPDB