3α,7α,12α-Trihydroxy-5β-cholestanoic acid
Lysosomal acid lipase/cholesteryl ester hydrolase
Peroxisomal multifunctional enzyme type 2
3 α,7 α,24-Trihydroxy-5β-cholestanoyl-CoA
3 beta-hydroxysteroid dehydrogenase type 7
Cholesterol (→) Transport: Rattus norvegicus, Extracellular Space to Rattus norvegicus, Liver, Cell
CE(22:2(13Z,16Z)) (→) Transport: Rattus norvegicus, Extracellular Space to Rattus norvegicus, Liver, Cell
7a-Hydroxy-5b-cholestan-3-one + NAD → 3a,7a-Dihydroxy-5b-cholestane + NADP
7a-Hydroxy-cholestene-3-one + NADPH ← 7a-Hydroxy-5b-cholestan-3-one + NADP
3a,7a-Dihydroxy-5b-cholestane + 3 NADPH + 3 Oxygen → 3 α,7 α,26-Trihydroxy-5β-cholestane + 3 NADP + 3 Water
3 α,7 α,26-Trihydroxy-5β-cholestane → 3a,7a-Dihydroxy-5b-cholestan-26-al
3a,7a-Dihydroxy-5b-cholestan-26-al → 3α,7α-Dihydroxycoprostanic acid
3α,7α-Dihydroxycoprostanic acid + Adenosine triphosphate + Coenzyme A → 3'-AMP + 3a,7a-Dihydroxy-5b-cholestanoyl-CoA + Pyrophosphate
3a,7a-Dihydroxy-5b-cholestanoyl-CoA → 3a,7a-Dihydroxy-5b-cholestanoyl-CoA
3a,7a-Dihydroxy-5b-cholestanoyl-CoA + Water → 3a,7a-Dihydroxy-5b-cholest-24-enoyl-CoA
3 α,7 α,24-Trihydroxy-5β-cholestanoyl-CoA → Chenodeoxycholoyl-CoA + Water
Chenodeoxycholoyl-CoA + Coenzyme A → Chenodeoxycholoyl-CoA + Propionyl-CoA
Chenodeoxycholoyl-CoA + Taurine → Taurochenodesoxycholic acid
Chenodeoxycholoyl-CoA + Glycine → Chenodeoxycholic acid glycine conjugate + Glycocholic acid
Adenosine triphosphate + Chenodeoxycholoyl-CoA + Cholic acid → 3'-AMP + Chenodeoxycholic acid + Pyrophosphate
7a-Hydroxycholesterol + NAD → 7a-Hydroxy-cholestene-3-one + NADH
7a-Hydroxy-cholestene-3-one + NADPH + Oxygen → 7a,12a-Dihydroxy-cholestene-3-one + NADP + Water
Cholesterol + NADPH + Oxygen → 7a-Hydroxycholesterol + NADP + Water
CE(22:2(13Z,16Z)) + Water → Cholesterol + Palmitic acid
7a,12a-Dihydroxy-cholestene-3-one + NADPH → 7a,12a-Dihydroxy-5b-cholestan-3-one + NADP
5-b-Cholestane-3a ,7a ,12a-triol + 3 NADPH + 3 Oxygen → 27-Deoxy-5b-cyprinol + 3 NADP + 4 Water
7a,12a-Dihydroxy-5b-cholestan-3-one + NADP → 5-b-Cholestane-3a ,7a ,12a-triol + NADPH
27-Deoxy-5b-cyprinol + 3 NADPH + 3 Oxygen → 3a,7a,12a-Trihydroxy-5b-cholestan-26-al + 3 NADP + 4 Water
3a,7a,12a-Trihydroxy-5b-cholestan-26-al → 3α,7α,12α-Trihydroxy-5β-cholestanoic acid
3α,7α,12α-Trihydroxy-5β-cholestanoic acid + Adenosine triphosphate + Coenzyme A → 3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA + Adenosine diphosphate + Pyrophosphate
3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA → 3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA
3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA + Acceptor + Water → 3a,7a,12a-Trihydroxy-5b-cholest-24-enoyl-CoA + Reduced acceptor
3a,7a,12a,24-Tetrahydroxy-5b-cholestanoyl-CoA + NAD → 3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA + NADH
Choloyl-CoA + Taurine → Coenzyme A + Taurocholic acid
Choloyl-CoA + Glycine → Coenzyme A + Glycocholic acid
3'-AMP + Choloyl-CoA + Pyrophosphate → Adenosine triphosphate + Cholic acid + Coenzyme A
Cholesterol + NADPH + Oxygen → 24-Hydroxycholesterol + NADP + Water
24-Hydroxycholesterol + NADPH + Oxygen → (24R)-Cholest-5-ene-3-β,7-α,24-triol + NADP + Water
25-Hydroxycholesterol + NADPH + Oxygen → 7-a,25-Dihydroxycholesterol + NADP + Water
Cholesterol + 3 NADPH + 3 Oxygen → 27-Hydroxycholesterol + 3 NADP + 4 Water
27-Hydroxycholesterol + NADPH + Oxygen → 7-a,27-Dihydroxycholesterol + NADP + Water
27-Hydroxycholesterol + 3 NADPH + 3 Oxygen → 3 β-Hydroxy-5-cholestenoate + 3 NADP + 4 Water
3 β-Hydroxy-5-cholestenoate + NADPH + Oxygen → 3β,7α-Dihydroxy-5-cholestenoate + NADP + Water
3β,7α-Dihydroxy-5-cholestenoate + NAD → 7α-Hydroxy-3-oxo-4-cholestenoate + NADH
3a,7a,12a-Trihydroxy-5b-cholest-24-enoyl-CoA + Water → 3a,7a,12a,24-Tetrahydroxy-5b-cholestanoyl-CoA
3a,7a,12a-Trihydroxy-5b-24-oxocholestanoyl-CoA + Coenzyme A → Choloyl-CoA + Propionyl-CoA
AH2 + Cholesterol + Oxygen → 25-Hydroxycholesterol + A + Water
7-a,27-Dihydroxycholesterol + NADP → 7 α,26-Dihydroxy-4-cholesten-3-one + NADPH
3a,7a-Dihydroxy-5b-cholest-24-enoyl-CoA + Water → 3 α,7 α,24-Trihydroxy-5β-cholestanoyl-CoA
25-hydroxycholesterol 7-alpha-hydroxylase
Bile acid-CoA:amino acid N-acyltransferase
27-Deoxy-5b-cyprinol → 5b-Cyprinol sulfate