C20H32O2
Arachidonic acid
304.24023
CHEBI:15843
ChEBI
Interaction2090
Growth factor receptor-bound protein 2 activates Son of sevenless homolog 1
Cyclic AMP-dependent transcription factor ATF-4
Unknown
direct_interaction
Gonadoliberin
Q29W20
UniProt
1.0
Phosphate_Dual specificity mitogen-activated protein kinase kinase 7 (Bos taurus)
Inositol 1,4,5-trisphosphate receptor type 1
Q2KJE6
UniProt
Q2KIC2
UniProt
P04837
UniProt
9913
TAXONOMY
Inositol 1,4,5-trisphosphate receptor type 1
Phosphate_Dual specificity mitogen-activated protein kinase kinase 7 (Bos taurus)
Mitogen-activated protein kinase 13
1.0
Ternary complex (LRRC7, CAMK2a, ACTN4)
1.0
Mitogen-activated protein kinase 1
Aurora kinase A
Q7M2U0
UniProt
P01217
UniProt
A5D7D1
UniProt
C10H12N5O6P
cAMP
329.05252
Guanine nucleotide-binding protein subunit alpha-11
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
cAMP-dependent protein kinase catalytic subunit alpha
Phosphate_Mitogen-activated protein kinase 1 (Bos taurus)
Cyclic AMP-dependent transcription factor ATF-4
C00219
KEGG Compound
C00575
KEGG Compound
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
E1BIN8
UniProt
Rap guanine nucleotide exchange factor 2
Activated CDC42 kinase 1
1.0
A6QLK6
UniProt
Protein kinase C alpha type
1.0
O4P
Phosphate
94.95342
5851
ChemSpider
Mitogen-activated protein kinase 13
266
ChemSpider
Transport10250
false
Calcium (?) Transport: Bos taurus, Cell, Endoplasmic Reticulum to Bos taurus, Cell, Cytoplasm
LEFT_TO_RIGHT
Adenylate cyclase type 1
Tyrosine-protein kinase Fyn
Cytosolic phospholipase A2
1.0
Q2KI66
UniProt
2.0
DG
1.0
PW122188
PathWhiz
SMILES
[O-]P([O-])([O-])=O
Tyrosine-protein kinase Fyn
Heparin binding EGF like growth factor
GO:0005886
GENE ONTOLOGY
Mitogen-activated protein kinase 13
Voltage-depenent L-type calcium channel
C00009
KEGG Compound
Alpha-actinin-4
HMDB0001429
HMDB
Mitogen-activated protein kinase 14 (Bos taurus)_Phosphate
Q3T0N5
UniProt
CHEBI:18367
ChEBI
Heparin binding EGF like growth factor
1032
ChemSpider
Dual specificity mitogen-activated protein kinase kinase 6
HMDB0000464
HMDB
Transcription factor AP-1
Gonadotropin-releasing hormone receptor
Protein kinase C complex
Protein kinase C beta type
Activated CDC42 kinase 1
1.0
GO:0005634
GENE ONTOLOGY
Phosphate_Mitogen-activated protein kinase 1 (Bos taurus)
Heparin binding EGF like growth factor
Epidermal growth factor receptor
CHEBI:17489
ChEBI
O77627
UniProt
A7YY51
UniProt
CAMP
BioCyc
72 kDa type IV collagenase
4.0
Q3T0M4
UniProt
444899
PubChem-compound
Extracellular Space
Calmodulin
Unknown
Interaction2118
Epidermal growth factor receptor activates Growth factor receptor-bound protein 2
14127-61-8
CAS
SMILES
[Ca++]
1.0
GRB2-related adapter protein
2.0
DG
1.0
Ras-related protein Rap-1b
Matrix metalloproteinase-14
Guanine nucleotide-binding protein subunit alpha-11
Protein kinase C alpha type
Gonadotropin-releasing hormone receptor
GO:0005615
GENE ONTOLOGY
Dual specificity mitogen-activated protein kinase kinase 3 (Bos taurus)_Phosphate
CHEBI:29108
ChEBI
GO:0005737
GENE ONTOLOGY
Protein kinase C beta type
72 kDa type IV collagenase
P19754
UniProt
60-92-4
CAS
Arachidonic acid
cAMP
Q1XD55
UniProt
Activated CDC42 kinase 1
Endoplasmic Reticulum
A5D7N0
UniProt
Interaction2134
Voltage-dependent L-type calcium channel activates Protein kinase C complex
Interaction2135
Protein kinase C complex activates Voltage-depenent L-type calcium channel
Interaction2136
MMP2-MMP14 activates Proheparin-binding EGF-like growth factor
CPD-8587
BioCyc
Interaction2137
Proheparin-binding EGF-like growth factor activates Epidermal growth factor receptor
Dual specificity mitogen-activated protein kinase kinase 6
Interaction2130
Calmodulin-like protein 6 activates Ternary complex (LRRC7, CAMK2a, ACTN4)
Alpha-actinin-4
Leucine-rich repeat-containing protein 7
Interaction2131
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta1 activates DG
Interaction2132
DG activates Protein kinase C complex
Interaction2133
Calcium activates Voltage-dependent L-type calcium channel
P00517
UniProt
Calcium/calmodulin-dependent protein kinase type II subunit delta
Phospholipase D2
Interaction2138
Son of sevenless homolog 1 activates GTPase HRas
Epidermal growth factor receptor
Interaction2139
Cytosolic phospholipase A2 beta activates Arachidonic acid
A2VE60
UniProt
Calcium
1.0
Glycoprotein hormones alpha chain
Mitogen-activated protein kinase 1
IP3
Follitropin subunit beta
Phosphatidic Acid
392692
ChemSpider
ETS translocation variant 1
Lutropin subunit beta
Transcription factor AP-1
Phosphate
Interaction2123
Guanine nucleotide-binding protein alpha activates Adenylate cyclase type 1
Interaction2124
Adenylate cyclase type 1 activates cAMP
Interaction2125
cAMP activates cAMP-dependent protein kinase catalytic subunit alpha
Interaction2126
Guanine nucleotide-binding protein subunit alpha-11 activates 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta1
Glycoprotein hormones alpha chain
1.0
A0JNB0
UniProt
Bos taurus
Interaction2127
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta1 activates IP3
Interaction2128
IP3 activates Inositol 1,4,5-trisphosphate receptor type 1
Leucine-rich repeat-containing protein 7
Gonadoliberin
Interaction2129
Calcium activates Calmodulin-like protein 6
Gonadotropin-releasing hormone receptor
ETS translocation variant 1
Cytoplasm
Rap guanine nucleotide exchange factor 2
Serine/threonine-protein kinase 4
Phospholipase D2
Protein kinase C complex
Interaction2150
Mitogen-activated protein kinase kinase kinase 2 activates Dual specificity mitogen-activated protein kinase kinase 3 (Bos taurus) + Phosphate
Interaction2151
Dual specificity mitogen-activated protein kinase kinase 3 (Bos taurus) + Phosphate activates Mitogen-activated protein kinase 14 (Bos taurus) + Phosphate
O02742
UniProt
Interaction2156
Phosphate + Mitogen-activated protein kinase 1 (Bos taurus) activates Phosphate + Early growth response protein 1 (Bos taurus) + ELK1 (Bos taurus)
SMILES
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
Interaction2157
Phosphate + Early growth response protein 1 (Bos taurus) + ELK1 (Bos taurus) activates Lutropin subunit beta
Interaction2158
Phosphate + Early growth response protein 1 (Bos taurus) + ELK1 (Bos taurus) activates Glycoprotein hormones alpha chain
Interaction2159
Phosphate + Early growth response protein 1 (Bos taurus) + ELK1 (Bos taurus) activates Follitropin subunit beta
Interaction2152
Protein kinase C complex activates RAF proto-oncogene serine/threonine-protein kinase (Bos taurus) + Phosphate
Calcium/calmodulin-dependent protein kinase type II subunit delta
Interaction2153
GTPase HRas activates RAF proto-oncogene serine/threonine-protein kinase (Bos taurus) + Phosphate
Interaction2154
RAF proto-oncogene serine/threonine-protein kinase (Bos taurus) + Phosphate activates Dual specificity mitogen-activated protein kinase kinase 1 (Bos taurus) + Phosphate
Phosphatidic Acid
Interaction2155
Dual specificity mitogen-activated protein kinase kinase 1 (Bos taurus) + Phosphate activates Phosphate + Mitogen-activated protein kinase 1 (Bos taurus)
cAMP-dependent protein kinase catalytic subunit alpha
RAF proto-oncogene serine/threonine-protein kinase
Ras-related protein Rap-1b
GO:0005783
GENE ONTOLOGY
Cell division control protein 42 homolog
SMP0120925
SMPDB
P32236
UniProt
Interaction2140
Phospholipase D1 activates Phosphatidic Acid
Lutropin subunit beta
Interaction2145
Gonadotropin-releasing hormone receptor activates Guanine nucleotide-binding protein alpha
Interaction2146
cAMP-dependent protein kinase catalytic subunit alpha activates Cyclic AMP-dependent transcription factor ATF-4 (Bos taurus) + Phosphate
Interaction2147
Cyclic AMP-dependent transcription factor ATF-4 (Bos taurus) + Phosphate activates Follitropin subunit beta
Interaction2148
Cyclic AMP-dependent transcription factor ATF-4 (Bos taurus) + Phosphate activates Lutropin subunit beta
Interaction2141
Proto-oncogene tyrosine-protein kinase Src activates Cell division control protein 42 homolog
Interaction2142
Cell division control protein 42 homolog activates Mitogen-activated protein kinase kinase kinase 1
Phosphate_Mitogen-activated protein kinase 8 (Bos taurus)
Q2KJ93
UniProt
Interaction2143
Progonadoliberin-1 activates Gonadotropin-releasing hormone receptor
Early growth response protein 1
Interaction2144
Gonadotropin-releasing hormone receptor activates Guanine nucleotide-binding protein subunit alpha-11
IP3
GO:0016020
GENE ONTOLOGY
SMILES
NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O
Protein kinase C beta type
Interaction2149
Cyclic AMP-dependent transcription factor ATF-4 (Bos taurus) + Phosphate activates Glycoprotein hormones alpha chain
F1MSG6
UniProt
Aurora kinase A
Mitogen-activated protein kinase 1
Cytosolic phospholipase A2
Adenylate cyclase type 1
Cell division control protein 42 homolog
C00076
KEGG Compound
RAF proto-oncogene serine/threonine-protein kinase (Bos taurus)_Phosphate
Inositol 1,4,5-trisphosphate receptor type 1
CA%2b2
BioCyc
HMDB0000058
HMDB
Serine/threonine-protein kinase 4
Q2TA47
UniProt
Protein kinase C alpha type
Ca
Calcium
39.96259
MMP2-MMP14
Cell Membrane
Interaction2160
Mitogen-activated protein kinase kinase kinase 1 activates Phosphate + Dual specificity mitogen-activated protein kinase kinase 7 (Bos taurus)
Interaction2161
Phosphate + Dual specificity mitogen-activated protein kinase kinase 7 (Bos taurus) activates Phosphate + Mitogen-activated protein kinase 8 (Bos taurus)
14265-44-2
CAS
Interaction2162
Phosphate + Mitogen-activated protein kinase 8 (Bos taurus) activates Phosphate + Transcription factor AP-1 (Bos taurus)
Phosphate_Transcription factor AP-1 (Bos taurus)
271
PubChem-compound
Interaction2163
Phosphate + Transcription factor AP-1 (Bos taurus) activates Lutropin subunit beta
Interaction2164
Phosphate + Transcription factor AP-1 (Bos taurus) activates Glycoprotein hormones alpha chain
Phosphate
Interaction2165
Phosphate + Transcription factor AP-1 (Bos taurus) activates Follitropin subunit beta
Calcium
F1MCA7
UniProt
Calmodulin
Follitropin subunit beta
GnRH Signaling Pathway
Q08DV7
UniProt
P04409
UniProt
Membrane
GRB2-related adapter protein
P10894
UniProt
1.0
P04651
UniProt
Q9GLE5
UniProt
Q9GLE4
UniProt
Q5E9X2
UniProt
Early growth response protein 1
1.0
cAMP-dependent protein kinase catalytic subunit alpha
1.0
HMDB0001043
HMDB
Q3ZCH6
UniProt
Nucleus
Cyclic AMP-dependent transcription factor ATF-4 (Bos taurus)_Phosphate
506-32-1
CAS
1061
PubChem-compound
RAF proto-oncogene serine/threonine-protein kinase
Dual specificity mitogen-activated protein kinase kinase 1 (Bos taurus)_Phosphate
6076
PubChem-compound
Matrix metalloproteinase-14
1.0
Phosphate_Early growth response protein 1 (Bos taurus)_ELK1 (Bos taurus)
Calcium
Q2HJF7
UniProt
Q2TA06
UniProt
Unknown
1.0
IP3
ARACHIDONIC_ACID
BioCyc
Q0VBW7
UniProt
1.0
1.0
Dual specificity mitogen-activated protein kinase kinase 6